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https://www.readbyqxmd.com/read/28339685/information-needs-of-generalists-and-specialists-using-online-best-practice-algorithms-to-answer-clinical-questions
#1
David A Cook, Kristi J Sorensen, Jane A Linderbaum, Laurie J Pencille, Deborah J Rhodes
Objective: : To better understand clinician information needs and learning opportunities by exploring the use of best-practice algorithms across different training levels and specialties. Methods: : We developed interactive online algorithms (care process models [CPMs]) that integrate current guidelines, recent evidence, and local expertise to represent cross-disciplinary best practices for managing clinical problems. We reviewed CPM usage logs from January 2014 to June 2015 and compared usage across specialty and provider type...
February 19, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28339314/an-analysis-of-ems-and-ed-detection-of-stroke
#2
Ian Medoro, David C Cone
BACKGROUND AND PURPOSE: Studies have shown a reduction in time-to-CT and improved process measures when EMS personnel notify the ED of a "stroke alert" from the field. However, there are few data on the accuracy of these EMS stroke alerts. The goal of this study was to examine diagnostic test performance of EMS and ED stroke alerts and related process measures. METHODS: The EMS and ED records of all stroke alerts in a large tertiary ED from August 2013-January 2014 were examined and data abstracted by one trained investigator, with data accuracy confirmed by a second investigator for 15% of cases...
March 24, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28329559/factors-correlated-with-residents-decisions-to-enter-academic-dermatology
#3
Brenda M Morales-Pico, Cary C Cotton, Dean S Morrell
The demand for dermatologic services and training at academic medical centers has outpaced the growth in the field's academic workforce. Recruitment of graduating residents has been proposed as a solution to the shortage of academic dermatologists. The purpose of this study was to further our current understanding of the factors that support the recruitment and retention of academicians. A survey questionnaire was mailed to graduates of the dermatology residency program at the University of North Carolina, and data were gathered retrospectively from participants' residency application materials...
November 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28327987/pssmhcpan-a-novel-pssm-based-software-for-predicting-class-i-peptide-hla-binding-affinity
#4
Geng Liu, Dongli Li, Zhang Li, Si Qiu, Wenhui Li, Cheng-Chi Chao, Naibo Yang, Handong Li, Zhen Cheng, Xin Song, Le Cheng, Xiuqing Zhang, Jian Wang, Huanming Yang, Kun Ma, Yong Hou, Bo Li
Background: Predicting peptides binding affinity with human leukocyte antigen (HLA) is a crucial step in developing powerful antitumor vaccine for cancer immunotherapy. Currently available methods work quite well in predicting peptide binding affinity with HLA alleles such as HLA-A*0201, HLA-A*0101, and HLA-B*0702 in terms of sensitivity and specificity. However, quite a few types of HLA alleles that are present in majority of human populations including HLA-A*0202, HLA-A*0203, HLA-A*6802, HLA-B*5101, HLA-B*5301, HLA-B*5401 and HLA-B*5701 still cannot be predicted with satisfactory accuracy using currently available methods...
March 15, 2017: GigaScience
https://www.readbyqxmd.com/read/28327141/the-first-nationwide-survey-of-md-phds-in-the-social-sciences-and-humanities-training-patterns-and-career-choices
#5
Seth M Holmes, Jennifer Karlin, Scott D Stonington, Diane L Gottheil
BACKGROUND: While several articles on MD-PhD trainees in the basic sciences have been published in the past several years, very little research exists on physician-investigators in the social sciences and humanities. However, the numbers of MD-PhDs training in these fields and the number of programs offering training in these fields are increasing, particularly within the US. In addition, accountability for the public funding for MD-PhD programs requires knowledge about this growing population of trainees and their career trajectories...
March 21, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28325053/-iatrogenic-biliary-tract-lesions-requiring-surgical-reconstruction-presentation-and-classification-of-the-lesions-their-reconstruction-and-evaluation-of-the-results
#6
M Straka, E Holášková, L Burda, M Vávrová, P Fojtík, M Škrovina
INTRODUCTION: The incidence of biliary duct injuries requiring surgical reconstruction has stabilised between 0.30.7%. Biliary reconstruction in the hands of a trained hepatobiliary surgeon may lead to better short- and long-term outcomes in patients with this infrequent, but serious complication. METHODS: This study presents a retrospective analysis of single surgeon experience with biliary injury repair during the period of 20072016. Extramucosal hepaticojejunostomy on the excluded segment of the jejunal loop was performed without the use of any transanastomotic drain...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28324205/levels-of-intervention-how-are-they-used-in-quebec-hospitals
#7
Marjolaine Frenette, Jocelyne Saint-Arnaud, Karim Serri
In order to promote better practices and communication around end-of-life decision-making, several Canadian hospitals in the province of Quebec have developed a tool called "Levels of Intervention" (LOI). No work to date has been published demonstrating improvement since these forms were implemented. The purpose of the present study was to obtain information about the use of LOI forms across Quebec hospitals and to identify gaps in practice as well as areas for improvement. A retrospective study was undertaken of 299 charts of patients who had died in three Quebec hospitals with a LOI ordered...
March 21, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28321602/does-the-sense-of-coherence-modifies-the-relationship-of-oral-clinical-conditions-and-oral-health-related-quality-of-life
#8
Fernanda W Machado, Ana Paula Perroni, Gustavo G Nascimento, Marília L Goettems, Noéli Boscato
PURPOSE: This cross-sectional study aimed to evaluate the association of demographic and clinical characteristics, Sense of Coherence (SOC), clinical conditions (number of teeth, and use of and need for dental prostheses), and Oral Health-Related Quality of Life (OHRQoL); and if the SOC modifies the relationship of clinical conditions and OHRQoL in a sample of elders. METHODS: Trained dentists assessed the participants' oral health and conducted interviews (n = 110)...
March 20, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28321138/student-preparation-for-pgy1-residency-training-by-us-colleges-of-pharmacy-survey-of-the-residency-program-director-perspective
#9
Alyssa B Mutz, Jacob Beyer, Whitney L Dickson, Irina Gutman, Filiz Yucebay, Marcie Lepkowsky, Juliana Chan, Kristen Carter, Christopher L Shaffer, Patrick D Fuller
Purpose: To evaluate current residents' level of preparation by US colleges of pharmacy for postgraduate year 1 (PGY1) residency training from the perspective of residency program directors (RPDs). Methods: RPDs were asked in an electronic survey questionnaire to rate PGY1 pharmacy residents' abilities in 4 domains: communication, clinical knowledge, interpersonal/time-management skills, and professionalism/leadership. Results: One hundred ninety-seven RPDs of the American Society of Health-System Pharmacists (ASHP)-accredited PGY1 programs completed the survey...
February 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/28317658/minimally-invasive-pancreatoduodenectomy
#10
Michael L Kendrick, Jony van Hilst, Ugo Boggi, Thijs de Rooij, R Matthew Walsh, Herbert J Zeh, Steven J Hughes, Yoshiharu Nakamura, Charles M Vollmer, David A Kooby, Horacio J Asbun
BACKGROUND: Minimally invasive pancreatoduodenectomy (MIPD) is increasingly performed with several institutional series and comparative studies reported. The aim was to conduct an assessment of the best-evidence and expert opinion on the current status and future challenges of MIPD. METHODS: A systematic review of the literature was performed and best-evidence presented at a State-of-the-Art conference on Minimally Invasive Pancreatic Resection. Expert panel discussion and audience response activity was used to assess perceived value and future direction...
March 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28317507/effects-of-a-hybrid-online-and-in-person-training-program-designed-to-reduce-alcohol-sales-to-obviously-intoxicated-patrons
#11
Traci L Toomey, Kathleen M Lenk, Darin J Erickson, Keith J Horvath, Alexandra M Ecklund, Dawn M Nederhoff, Shanda L Hunt, Toben F Nelson
OBJECTIVE: Overservice of alcohol (i.e., selling alcohol to intoxicated patrons) continues to be a problem at bars and restaurants, contributing to serious consequences such as traffic crashes and violence. We developed a training program for managers of bars and restaurants, eARM™, focusing on preventing overservice of alcohol. The program included online and face-to-face components to help create and implement establishment-specific policies. METHOD: We conducted a large, randomized controlled trial in bars and restaurants in one metropolitan area in the midwestern United States to evaluate effects of the eARM program on the likelihood of selling alcohol to obviously intoxicated patrons...
March 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28293256/ranking-support-vector-machine-with-kernel-approximation
#12
Kai Chen, Rongchun Li, Yong Dou, Zhengfa Liang, Qi Lv
Learning to rank algorithm has become important in recent years due to its successful application in information retrieval, recommender system, and computational biology, and so forth. Ranking support vector machine (RankSVM) is one of the state-of-art ranking models and has been favorably used. Nonlinear RankSVM (RankSVM with nonlinear kernels) can give higher accuracy than linear RankSVM (RankSVM with a linear kernel) for complex nonlinear ranking problem. However, the learning methods for nonlinear RankSVM are still time-consuming because of the calculation of kernel matrix...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28293194/quantification-of-internal-stress-strain-fields-in-human-tendon-unraveling-the-mechanisms-that-underlie-regional-tendon-adaptations-and-mal-adaptations-to-mechanical-loading-and-the-effectiveness-of-therapeutic-eccentric-exercise
#13
REVIEW
Constantinos N Maganaris, Panagiotis Chatzistergos, Neil D Reeves, Marco V Narici
By virtue of their anatomical location between muscles and bones, tendons make it possible to transform contractile force to joint rotation and locomotion. However, tendons do not behave as rigid links, but exhibit viscoelastic tensile properties, thereby affecting the length and contractile force in the in-series muscle, but also storing and releasing elastic stain energy as some tendons are stretched and recoiled in a cyclic manner during locomotion. In the late 90s, advancements were made in the application of ultrasound scanning that allowed quantifying the tensile deformability and mechanical properties of human tendons in vivo...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28289974/sage-s-advice-application-of-a-standardized-train-the-trainer-model-for-faculty-involved-in-a-society-of-american-gastrointestinal-and-endoscopic-surgeons-sages-hands-on-course
#14
Susannah M Wyles, Erin Schwarz, Jonathan Dort, Nabil Tariq, Tom Cecil, Mark G Coleman, John Paige, Brian J Dunkin
INTRODUCTION: Currently, no prerequisite teaching qualification is required to serve as faculty for SAGES hands-on courses (SAGES-HOC). The Lapco-Train-the-Trainers (Lapco-TT) is a course for surgical trainers, in which delegates learn a standardized teaching technique for skills acquisition. The aims of this study were to 1) determine if this curriculum could be delivered in a day course to SAGES-HOC faculty and 2) assess the impact of such training on learners' educational experience taught by this faculty at a subsequent SAGES-HOC...
March 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28289680/synergy-repetition-training-versus-task-repetition-training-in-acquiring-new-skill
#15
Vrajeshri Patel, Jamie Craig, Michelle Schumacher, Martin K Burns, Ionut Florescu, Ramana Vinjamuri
Traditionally, repetitive practice of a task is used to learn a new skill, exhibiting as immediately improved performance. Research suggests, however, that a more experience-based rather than exposure-based training protocol may allow for better transference of the skill to related tasks. In synergy-based motor control theory, fundamental motor skills, such as hand grasping, are represented with a synergy subspace that captures essential motor patterns. In this study, we propose that motor-skill learning through synergy-based mechanisms may provide advantages over traditional task repetition learning...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28289296/methods-used-by-colleges-and-schools-of-pharmacy-to-prepare-student-pharmacists-for-careers-in-academia
#16
Seena L Haines, Eliza A Dy-Boarman, Kalin M Clifford, Maria A Summa, Megan N Willson, Jaclyn A Boyle, Michael J Peeters
Objective. To identify the methods used by US colleges and schools of pharmacy to prepare student pharmacists for academic careers. Method. An 18-item survey instrument was developed and distributed to US colleges and schools of pharmacy. Representatives were asked about faculty responsibilities, experiences in academia currently offered to student pharmacists, and representatives' perception of their student pharmacists' preparedness for careers in academia, including barriers in current programming. Results...
February 25, 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28286168/predcar-site-carbonylation-sites-prediction-in-proteins-using-support-vector-machine-with-resolving-data-imbalanced-issue
#17
Md Al Mehedi Hasan, Jinyan Li, Shamim Ahmad, Md Khademul Islam Molla
The carbonylation is found as an irreversible post-translational modification and considered a biomarker of oxidative stress. It plays major role not only in orchestrating various biological processes but also associated with some diseases such as Alzheimer's disease, diabetes, and Parkinson's disease. However, since the experimental technologies are costly and time-consuming to detect the carbonylation sites in proteins, an accurate computational method for predicting carbonylation sites is an urgent issue which can be useful for drug development...
March 9, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28283358/identify-and-analysis-crotonylation-sites-in-histone-by-using-support-vector-machines
#18
Wang-Ren Qiu, Bi-Qian Sun, Hua Tang, Jian Huang, Hao Lin
OBJECTIVE: Lysine crotonylation (Kcr) is a newly discovered histone posttranslational modification, which is specifically enriched at active gene promoters and potential enhancers in mammalian cell genomes. Although lysine crotonylation sites can be correctly identified with high-resolution mass spectrometry, the experimental methods are time-consuming and expensive. Therefore, it is necessary to develop computational methods to deal with this problem. METHODS: We proposed a new encoding scheme named position weight amino acid composition to extract sequence information of histone around crotonylation sites...
March 7, 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/28281118/evaluation-of-different-time-schedules-in-training-with-the-da-vinci-simulator
#19
C Güldner, A Orth, P Dworschak, I Diogo, M Mandapathil, A Teymoortash, U Walliczek-Dworschak
BACKGROUND: This prospective study analyzed the effect of different time schedules in training on the main performance outcomes: overall score, time to complete, and economy of motion. METHODS: The study was performed on the da Vinci Skills Simulator from December 2014 to April 2016. Forty robotic novices were randomized into two groups of 20 participants, which trained in the same three exercises but with different intervals between their training sessions. Each group performed training in Peg Board 1 in their first week, Match Board 2 in their second week, and Ring and Rail 2 in their third week...
March 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28281117/game-based-training-improves-the-surgeon-s-situational-awareness-in-the-operation-room-a-randomized-controlled-trial
#20
Maurits Graafland, Willem A Bemelman, Marlies P Schijven
BACKGROUND: Equipment-related malfunctions directly relate to one-fourth of the adverse events in the surgical theater. A serious game trains residents to recognize and respond to equipment problems in minimally invasive surgery (MIS). These include disturbed vision, gas transport, electrocautery, and pathophysiological disturbances. This randomized controlled trial explores whether game-based training improves surgical residents' response to equipment-related problems during surgery...
March 9, 2017: Surgical Endoscopy
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