keyword
https://read.qxmd.com/read/38530771/clinical-practice-guidelines-for-prevention-and-treatment-of-postoperative-gastrointestinal-disorder-with-integrated-traditional-chinese-and-western-medicine-2023
#1
JOURNAL ARTICLE
Jianjun Xue, Ziqing Xu, Qiang Wang, Huaijing Hou, Lili Wei, Jie Zhang, Xiaohong Zhao, Liping Chen, Fanfan Ding, Li Ma, Yongqiang Zhao, Yingbin Wang, Daqing Ma, Tianjun Wang, Renyu Liu, Tong J Gan, Nicky Robinson, Yurasek Frank, Fan Su, Yongliang Chi, Dianhui Yang, Shujuan Liu, Suyang Cui, Yousong Wei, Zhiqiang Chen, You Qin, Lixing Cao, Guiping Chen, Kuanyong Shu, Zhongqing Xiao, Hui Zhang, Jianbo Yu, Zhiqian Hu, Huakun Cheng, Wuhua Ma, Guokai Liu, Xiuli Wang, Xinghua Cao, Ju Gao, Gaoyin Kong, Qing Tao, Baohua Wang, Junlu Wang, Hong Li, Cuixia Lyu, Zhiming Zhang, Tianzuo Li, Kehu Yang
Postoperative gastrointestinal disorder (POGD) was a common complication after surgery under anesthesia. Strategies in combination with Traditional Chinese Medicine and Western medicine showed some distinct effects but standardized clinical practice guidelines were not available. Thus, a multidisciplinary expert team from various professional bodies including the Perioperative and Anesthesia Professional Committees of the Chinese Association of Integrative Medicine (CAIM), jointly with Gansu Province Clinical Research Center of Integrative Anesthesiology/Anesthesia and Pain Medical Center of Gansu Provincial Hospital of Traditional Chinese Medicine and WHO Collaborating Center for Guideline Implementation and Knowledge Translation/Chinese Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) Center/Gansu Provincial Center for Medical Guideline Industry Technology/Evidence-based Medicine Center of Lanzhou University, was established to develop evidence-based guidelines...
March 26, 2024: Journal of Evidence-based Medicine
https://read.qxmd.com/read/38490894/opioid-prescribing-rate-for-nonoperative-distal-radius-fractures-and-clinician-response-to-a-clinical-decision-support-alert
#2
JOURNAL ARTICLE
Ben Averkamp, Katherine Li, Meghan K Wally, Tamar Roomian, Christopher Griggs, Michael Runyon, Joseph R Hsu, Rachel B Seymour, Michael Beuhler, Michael J Bosse, Manuel Castro, Michael Gibbs, Steven Jarrett, Daniel Leas, Susan Odum, Ziqing Yu, James Rachal, Animita Saha, D Matthew Sullivan, Brad Watling
BACKGROUND: Opioids are commonly prescribed for the management of acute orthopedic trauma pain, including nonoperative distal radius fractures. OBJECTIVES: This prospective study aimed to determine if a clinical decision support intervention influenced prescribing decisions for patients with known risk factors. We sought to quantify frequency of opioid prescriptions for acute nonoperative distal radius fractures treated. METHODS: We performed a prospective study at one large health care system...
December 22, 2023: Journal of Emergency Medicine
https://read.qxmd.com/read/38488456/vasorin-exocytosed-from-glioma-cells-facilitates-angiogenesis-via-vegfr2-akt-signaling-pathway
#3
JOURNAL ARTICLE
Ying Zhong, Hui Kang, Ziqing Ma, Jiayu Li, Zixi Qin, Zixuan Zhang, Peiwen Li, Ying Zhong, Lihui Wang
Glioma is a highly vascularized tumor of the central nervous system. Angiogenesis plays a predominant role in glioma progression and is considered an important therapeutic target. Our previous study showed that vasorin (VASN), a transmembrane protein, is overexpressed in glioma and promotes angiogenesis; however, the potential mechanism remains unclear. In this study, we found that human vascular endothelial cells (hECs) co-cultured with VASN-overexpressing glioma cells exhibited accelerated migration ability and increased expression of VASN originated from glioma cells...
March 15, 2024: Molecular Cancer Research: MCR
https://read.qxmd.com/read/38468490/nsun2-promotes-colorectal-cancer-progression-by-enhancing-skil-mrna-stabilization
#4
JOURNAL ARTICLE
Shaomin Zou, Yizhi Huang, Ziqing Yang, Jieping Zhang, Manqi Meng, Yijing Zhang, Junyan Feng, Rui Sun, Weiyao Li, Wencong Wang, Jesús García-Foncillas López, Lekun Fang
BACKGROUND: NOP2/Sun domain 2 (NSUN2) is one of the important RNA methyltransferases catalyzing 5-methylcytosine (m5C) formation and participates in many critical bioprocesses. However, the roles and underlying molecular mechanisms of NSUN2-mediated m5C modification in colorectal cancer (CRC) remain unclear. METHODS: To explore the NSUN2 expression in CRC, fresh tissue samples were collected and Nsun2 knockout mouse was constructed. In vitro and in vivo functional assays were conducted to assess the role of NSUN2...
March 2024: Clinical and Translational Medicine
https://read.qxmd.com/read/38466602/learning-rates-of-deep-nets-for-geometrically-strongly-mixing-sequence
#5
JOURNAL ARTICLE
Yueyang Men, Liang Li, Ziqing Hu, Yongli Xu
The great success of deep learning poses an urgent challenge to establish the theoretical basis for its working mechanism. Recently, research on the convergence of deep neural networks (DNNs) has made great progress. However, the existing studies are based on the assumption that the samples are independent, which is too strong to be applied to many real-world scenarios. In this brief, we establish a fast learning rate for the empirical risk minimization (ERM) on DNN regression with dependent samples, and the dependence is expressed in terms of geometrically strongly mixing sequence...
March 11, 2024: IEEE Transactions on Neural Networks and Learning Systems
https://read.qxmd.com/read/38438907/transmembrane-protein-176b-regulates-amino-acid-metabolism-through-the-pi3k-akt-mtor-signaling-pathway-and-promotes-gastric-cancer-progression
#6
JOURNAL ARTICLE
Jing Li, ZiQing Fang, Emre Dal, Hao Zhang, KeXun Yu, MengDi Ma, MingLiang Wang, Ruochuan Sun, MingDian Lu, HuiZhen Wang, YongXiang Li
BACKGROUND: The present study aimed to investigate the expression level, biological function, and underlying mechanism of transmembrane protein 176B (TMEM176B) in gastric cancer (GC). METHODS: TMEM176B expression was detected by quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting (WB). The function of TMEM176B was determined by various in vitro assays including colony formation, 5-ethynyl-2'-deoxyuridine (EdU), Transwell, and flow cytometry...
March 4, 2024: Cancer Cell International
https://read.qxmd.com/read/38434342/reliability-validity-and-responsiveness-of-the-simplified-chinese-version-of-the-knee-injury-and-osteoarthritis-outcome-score-in-patients-after-total-knee-arthroplasty
#7
JOURNAL ARTICLE
Runlan Yao, Liying Yang, Jianhua Wang, Qiao Zhou, Xucheng Li, Ziqing Yan, Yanfen Fu
OBJECTIVES: The Knee Injury and Osteoarthritis Outcome Score (KOOS) has been utilized to evaluate short- and long-term outcomes in individuals following knee injuries, such as those with anterior cruciate ligament reconstruction and knee osteoarthritis, but has not yet been applied to individuals undergoing total knee arthroplasty (TKA) in China. The aim of this study was to assess the psychometric properties of the Simplified Chinese version of the KOOS in Chinese individuals undergoing TKA...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38428081/intelligent-chemical-profiling-of-73-edible-flowers-by-liquid-chromatography-high-resolution-mass-spectrometry-combined-with-hrms-database-and-their-authentication-based-on-large-scale-fingerprints
#8
JOURNAL ARTICLE
Ziqing Li, Jianqing Zhang, Lin Yang, Xiaolan Li, Qian Meng, Yun Li, Shuai Yao, Wenlong Wei, Qirui Bi, Hua Qu, Yaling An, De-An Guo
A commercial high-resolution MS database "TCM-PCDL" was innovatively introduced to automatically identify multi-components in 73 edible flowers rapidly and accurately by liquid chromatography-high resolution mass spectrometry, which can be time-consuming and labor-intensive in traditional manual method. The database encompasses over 2565 natural products with various energy levels. Unknown compounds can be identified through direct matching and scoring MS2 spectra with database. A total of 870 compounds were identified from 73 flowers, with polyphenols constituting up to 75%...
February 6, 2024: Food Chemistry
https://read.qxmd.com/read/38420800/-ppp3cb-inhibits-cell-proliferation-and-the-warburg-effect-in-bladder-cancer-by-blocking-pdhk1
#9
JOURNAL ARTICLE
Xiangmin Qiu, Ziqing Jiang, Yu Luo, Dayu Tian, Tao Song, Qianyin Li
BACKGROUND: Cancer treatment has recently shifted towards metabolic approaches aimed at enhancing therapeutic efficacy. Somewhat surprisingly, a known regulator of energy metabolism in normal tissues, PPP3CB , is down-regulated in bladder cancer. This suggests that PPP3CB could exert an inhibitory effect on bladder cancer through its role in energy metabolism. METHODS: To explore the above hypothesis, we employed non-targeted metabolism screening in bladder cancer cells with knockdown of PPP3CB ...
February 4, 2024: Frontiers in Bioscience (Landmark Edition)
https://read.qxmd.com/read/38410569/comparison-of-safety-and-anxiety-depression-in-computed-tomography-guided-hook-wire-localization-versus-electromagnetic-navigation-bronchoscopy-guided-localization-a-retrospective-cohort-study
#10
JOURNAL ARTICLE
Tian Xia, Yongsen Li, Ziqing Shen, Ziyao Fang, Jun Chen, Shu Pan, Kunpeng Feng, Jing Huang, Cheng Ding, Jun Zhao
BACKGROUND: The utilization of computed tomography (CT)-guided localization and electromagnetic navigation bronchoscopy (ENB)-guided localization has gained significant traction in the localization of pulmonary nodules before video-assisted thoracoscopic surgery (VATS). This study aimed to ascertain the precision and safety of the two groups in the preoperative resection of isolated nodules in small peripheral lungs. Furthermore, we examined the subsequent outcomes pertaining to the decline in lung function and alterations in anxiety and depression following resection utilizing both localization techniques...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38401668/accumulation-of-nmda-receptors-in-accumbal-neuronal-ensembles-mediates-increased-conditioned-place-preference-for-cocaine-after-prolonged-withdrawal
#11
JOURNAL ARTICLE
Ziqing Huai, Bing Huang, Guanhong He, Haibo Li, Yonghui Liu, Qiumin Le, Feifei Wang, Lan Ma, Xing Liu
Cue-induced cocaine craving gradually intensifies following abstinence, a phenomenon known as the incubation of drug craving. Neuronal ensembles activated by initial cocaine use, are critically involved in this process. However, the mechanisms by which neuronal changes occurring in the ensembles after withdrawal contribute to incubation remain largely unknown. Here we labeled neuronal ensembles in the shell of NAc (NAcSh) activated by cocaine conditioned place preference (CPP) training. NAcSh ensembles showed an increasing activation induced by CPP test after 21-day withdrawal...
February 22, 2024: Progress in Neurobiology
https://read.qxmd.com/read/38394815/chiral-ligands-and-photothermal-synergistic-effects-of-inorganic-nanoparticles-for-bacteria-killing
#12
JOURNAL ARTICLE
Yuchao Du, Yarong Gu, Wenhe Wang, Yutao Jiang, Xiaosheng Fang, Ziqing Li, Lili Niu, Lijuan Zhao
As the drawbacks of antibiotics in treating bacterial infections emerged, physical methods such as near-infrared-activated (NIR-activated) bacterial killing, have attracted great interests for their advantages of no resistance, short action time and few side effects. In this manuscript, NIR-activated bacteria-killing performance of chiral copper sulphide nanoparticles (L-/d-CuS NPs) was investigated using linearly polarized light (LPL) and circularly polarized light (CPL) as illumination sources, respectively...
February 18, 2024: Journal of Colloid and Interface Science
https://read.qxmd.com/read/38373462/mechanistic-study-of-transcription-factor-sox18-during-heart-development
#13
JOURNAL ARTICLE
Jianxin Liang, Imtiaz Ul Hassan, Man Yee Cheung, Lei Feng, Yi-Jyun Lin, Qi Long, Chengdong Wang, Yuyue Ding, Ziqing Wang, Yuan Zhang, Yulong Li, Donghao Guo, Xiaofang Guo, Thomas Chi Bun Wong, Muhammad Kaleem Samma, Zixin Rong, Xufeng Qi, Dongqing Cai, Sai-Ming Ngai, Hui Zhao
Heart development is a delicate and complex process regulated by coordination of various signaling pathways. In this study, we investigated the role of sox18 in heart development by modulating Wnt/β-Catenin signaling pathways. Our spatiotemporal expression analysis revealed that sox18 is mainly expressed in the heart, branchial arch, pharyngeal arch, spinal cord, and intersegmental vessels at the tailbud stage of Xenopus tropicalis embryo. Overexpression of sox18 in the X. tropicalis embryos causes heart edema, while loss-of-function of sox18 can change the signal of developmental heart marker gata4 at different stages, suggesting that sox18 plays an essential role in the development of the heart...
February 17, 2024: General and Comparative Endocrinology
https://read.qxmd.com/read/38363033/the-effect-of-bioactivity-of-airway-epithelial-cells-using-methacrylated-gelatin-scaffold-loaded-with-exosomes-derived-from-bone-marrow-mesenchymal-stem-cells
#14
JOURNAL ARTICLE
Yongsen Li, Zhike Chen, Tian Xia, Haoxin Wan, Yi Lu, Cheng Ding, Fangbiao Zhang, Ziqing Shen, Shu Pan
The current evidence provides support for the involvement of bone marrow mesenchymal stem cells (BMSCs) in the regulation of airway epithelial cells. However, a comprehensive understanding of the underlying biological mechanisms remains elusive. This study aimed to isolate and characterize BMSC-derived exosomes (BMSC-Exos) and epithelial cells (ECs) through primary culture. Subsequently, the impact of BMSC-Exos on ECs was assessed in vitro, and sequencing analysis was conducted to identify potential molecular mechanisms involved in these interactions...
February 16, 2024: Journal of Biomedical Materials Research. Part A
https://read.qxmd.com/read/38358085/identification-of-the-novel-hla-c-03-132-02-allele-in-a-chinese-individual-by-next-generation-sequencing
#15
JOURNAL ARTICLE
Ziqing Wang, Yamin Sun, Yiqing Kang, Jianbin Li, Zheng Liu
Compared with the HLA-C*03:132:01 allele, HLA-C*03:132:02 shows one nucleotide substitution at position 270A>C.
February 2024: HLA
https://read.qxmd.com/read/38347637/connexin32-gap-junction-channels-deliver-mir155-3p-to-mediate-pyroptosis-in-renal-ischemia-reperfusion-injury
#16
JOURNAL ARTICLE
Liubing Chen, Hongyi Fang, Xiaoyun Li, Peiling Yu, Yu Guan, Cuicui Xiao, Zhizhao Deng, Ziqing Hei, Chaojin Chen, Chenfang Luo
OBJECTIVES: To explore whether the gap junction (GJ) composed by connexin32(Cx32) mediated pyroptosis in renal ischemia-reperfusion(I/R) injury via transmitting miR155-3p, with aim to provide new strategies for the prevention and treatment of acute kidney injury (AKI) after renal I/R. METHODS: 8-10 weeks of male C57BL/ 6 wild-type mice and Cx32 knockdown mice were divided into two groups respectively: control group and renal I/R group. MCC950 (50 mg/kg...
February 12, 2024: Cell Communication and Signaling: CCS
https://read.qxmd.com/read/38344291/effects-of-functional-correction-training-on-movement-patterns-and-physical-fitness-in-male-college-students
#17
JOURNAL ARTICLE
Zhiyong Zhang, Lunxin Chen, Ziqing Qin, Jiaxin He, Chong Gao, Jian Sun, Jiancai Chen, Duanying Li
The objective of this study is to investigate the effects of functional corrective training and static stretching on the quality of movement patterns and physical fitness in college students. The study was conducted with 30 male college students from a university in Guangzhou, China. The participants were randomly assigned to either the functional corrective training group (FCT, n = 15, age = 20.93 ± 0.85, BMI = 22.07 ± 2.33) or the static stretching group (SS, n = 13, age = 20.85 ± 0.86, BMI = 21...
2024: PeerJ
https://read.qxmd.com/read/38334061/electroacupuncture-ameliorates-neuroinflammation-by-inhibiting-trpv4-channel-in-ischemic-stroke
#18
JOURNAL ARTICLE
Xueqi Ren, Xinyi Gao, Ziqing Li, Yangyang Ding, Ao Xu, Lixia Du, Yufang Yang, Deheng Wang, Zhifei Wang, Shi Shu
AIMS: We investigated the potential mechanisms underlying the therapeutic efficacy of electroacupuncture (EA) at the Shuigou (GV26) and Baihui (GV20) acupoints in the treatment of ischemic stroke. METHODS: We assessed the therapeutic effects of EA on MCAO mice through behavioral studies and TTC staining. Various techniques, such as RT-PCR, immunofluorescence, and Western blots, were employed to evaluate the activation and polarization of microglia/macrophages, and changes in the TRPV4 ion channel...
February 2024: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/38333440/comparison-of-dosage-of-glucocorticoid-in-idiopathic-membranous-nephropathy-a-systematic-review-and-network-meta-analysis
#19
REVIEW
Yanhua Li, Ziqing Gao, Jianhong Zhu, Jianan Su, Pengwei Chen, Jiande Li, Min Feng
PURPOSE: Idiopathic membranous nephropathy (IMN) with moderate risk or above was recommended to receive immunosuppressive therapy. We attempted to evaluate the optimal dose of glucocorticoid when combined with evidence-proven effective immunosuppressants by network meta-analysis. METHODS: A systematic review of the literature was conducted in PubMed, Embase, Cochrane Library, and ClinicalTrials.gov from inception until January 2022. Randomized controlled trials (RCTs) in IMN limited to supportive care, glucocorticoids, cyclophosphamide, chlorambucil, calcineurin inhibitors (CNIs), and rituximab were screened...
January 2024: Curēus
https://read.qxmd.com/read/38331803/adipose-derived-stem-cells-in-immune-related-skin-disease-a-review-of-current-research-and-underlying-mechanisms
#20
REVIEW
Tianyi Sun, Cheng Zhou, Feng Lu, Ziqing Dong, Jianhua Gao, Bin Li
Adipose-derived stem cells (ASCs) are a critical adult stem cell subpopulation and are widely utilized in the fields of regenerative medicine and stem cell research due to their abundance, ease of harvest, and low immunogenicity. ASCs, which are homologous with skin by nature, can treat immune-related skin diseases by promoting skin regeneration and conferring immunosuppressive effects, with the latter being the most important therapeutic mechanism. ASCs regulate the immune response by direct cell-cell communication with immune cells, such as T cells, macrophages, and B cells...
February 8, 2024: Stem Cell Research & Therapy
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