keyword
MENU ▼
Read by QxMD icon Read
search

icad

keyword
https://www.readbyqxmd.com/read/29707662/molecular-analysis-of-immune-evasion-cluster-iec-genes-and-intercellular-adhesion-gene-cluster-ica-among-methicillin-resistant-and-methicillin-sensitive-isolates-of-staphylococcus-aureus
#1
R Ahmadrajabi, S Layegh-Khavidaki, D Kalantar-Neyestanaki, Y Fasihi
Introduction: Resistance to antibiotics and presence of virulence factors play an important role in increased mortality associated with infection due to Staphylococcus aureus. In this study, we determine antibiotic resistance pattern, presence of the icaADBC locus as well as biofilm formation and distribution and diversity the immune evasion cluster (IEC) genes in clinical isolate of S. aureus from Kerman, Iran. Materials and methods: During 15 months, 100 clinical isolates S...
December 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/29674236/sub-lethal-ultraviolet-b-irradiation-and-poly-i-c-treatment-synergistically-induced-apoptosis-of-hacat-cells-through-nf-%C3%AE%C2%BAb-pathway
#2
Wuxiyar Otkur, Weiwei Liu, Jinda Wang, Xingfan Jia, Dianchao Huang, Fang Wang, Toshihiko Hayashi, Shin-Ichi Tashiro, Satoshi Onodera, Takashi Ikejima
Ultraviolet B (UVB) irradiation exerts multiple effects on skin cells, inducing apoptosis, senescence and carcinogenesis. Toll-like receptor 3, a member of pattern recognition receptors, is reported to initiate inflammation by recognizing double-strand RNA (dsRNA) released from UVB-irradiated cells. It has not been studied, however, whether apoptosis induction in UVB irradiation is attributed to TLR3 activation. Here, we report on the pro-apoptotic role of TLR3 in UVB-irradiated epidermal cells. Poly I:C, an analogue of dsRNA that activates TLR3, was used in combination with sub-lethal UVB (4...
April 16, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29626333/cross-sectional-associations-of-reallocating-time-between-sedentary-and-active-behaviours-on-cardiometabolic-risk-factors-in-young-people-an-international-children-s-accelerometry-database-icad-analysis
#3
Bjørge Herman Hansen, Sigmund Alfred Anderssen, Lars Bo Andersen, Maria Hildebrand, Elin Kolle, Jostein Steene-Johannessen, Susi Kriemler, Angie S Page, Jardena J Puder, John J Reilly, Luis B Sardinha, Esther M F van Sluijs, Niels Wedderkopp, Ulf Ekelund
INTRODUCTION: Sedentary time and time spent in various intensity-specific physical activity are co-dependent, and increasing time spent in one behaviour requires decreased time in another. OBJECTIVE: The aim of the present study was to examine the theoretical associations with reallocating time between categories of intensities and cardiometabolic risk factors in a large and heterogeneous sample of children and adolescents. METHODS: We analysed pooled data from 13 studies comprising 18,200 children and adolescents aged 4-18 years from the International Children's Accelerometry Database (ICAD)...
April 6, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29602616/intracranial-large-and-medium-artery-atherosclerotic-disease-and-stroke
#4
REVIEW
Sami Al Kasab, Colin P Derdeyn, Waldo R Guerrero, Kaustubh Limaye, Amir Shaban, Harold P Adams
BACKGROUND: Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide and is associated with a high risk of stroke recurrence. We sought to perform a literature review of the epidemiology, pathophysiology, and treatment options. METHODS: A literature review on recent studies evaluating the epidemiology, risk factors, clinical presentation, and treatment was reviewed. ICAD is particularly common in Africa and Asia. RESULTS: Although the medical management of ICAD has improved over the past decade, a subgroup of patients with ICAD remains at significantly high risk of stroke recurrence, and newer studies that aim at improving our understanding of ICAD and evaluating new treatment methods are currently under way...
March 27, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29531880/internal-carotid-artery-dissection-with-lidocaine-nerve-block-injection-trauma-a-rare-case-report
#5
Naureen Narula, Faraz Siddiqui, Nakul Katyal, Akshay Avula, Michel Chalhoub
Internal carotid artery dissection (ICAD) accounts for 25% of cerebrovascular accidents in young and middle-aged patients. Dissection occurs when the intimal wall of an artery is damaged as a result of trauma or defect. ICAD development after dental work is a relatively uncommon phenomenon. Our study highlights a rare presentation of ICAD that resulted from a direct lidocaine nerve block injection in a patient undergoing pulpotomy for a right maxillary second premolar tooth. We have described the case and reviewed the literature on this rare but potentially life-threatening phenomenon...
January 5, 2018: Curēus
https://www.readbyqxmd.com/read/29429115/frequency-of-enterotoxins-toxic-shock-syndrome-toxin-1-and-biofilm-formation-genes-in-staphylococcus-aureus-isolates-from-cows-with-mastitis-in-the-northeast-of-brazil
#6
F N Costa, N O Belo, E A Costa, G I Andrade, L S Pereira, I A Carvalho, R L Santos
Staphylococcus aureus is among the microorganisms more frequently associated with subclinical bovine mastitis. S. aureus may produce several virulence factors. This study aimed at determining the frequency of virulence factors such as enterotoxins, toxic shock syndrome toxin 1, and ica adhesion genes. In addition, we assessed antimicrobial drug resistance in S. aureus isolated from clinical and subclinical cases of mastitis. A total of 88 cows with clinical or subclinical mastitis were sampled, resulting in 38 S...
February 10, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29392583/a-comprehensive-tool-for-measuring-mammographic-density-changes-over-time
#7
Mikael Eriksson, Jingmei Li, Karin Leifland, Kamila Czene, Per Hall
BACKGROUND: Mammographic density is a marker of breast cancer risk and diagnostics accuracy. Density change over time is a strong proxy for response to endocrine treatment and potentially a stronger predictor of breast cancer incidence. We developed STRATUS to analyse digital and analogue images and enable automated measurements of density changes over time. METHOD: Raw and processed images from the same mammogram were randomly sampled from 41,353 healthy women...
February 1, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29388540/comparative-characterisation-of-the-biofilm-production-abilities-of-staphylococcus-epidermidis-isolated-from-human-skin-and-platelet-concentrates
#8
COMPARATIVE STUDY
Mariam Taha, Carissa Kohnen, Shruti Mallya, Yuntong Kou, Adriana Zapata, Sandra Ramirez-Arcos
PURPOSE: Staphylococcus epidermidis is the predominant contaminant of platelet concentrates (PCs), a blood product used to treat patients with platelet deficiencies. This microorganism is able to form surface-attached aggregates (biofilms) in human skin. Herein, the abundance of S. epidermidis biofilm-producers in contaminated PCs compared to skin isolates was explored. Furthermore, the potential positive selection of S. epidermidis biofilm-producers during the blood donation process and PC manufacturing was investigated...
February 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29351199/biofilm-forming-potential-of-staphylococcus-aureus-isolated-from-clinical-mastitis-cases-in-new-zealand
#9
Shirli Notcovich, Gina DeNicolo, Steve H Flint, Norman B Williamson, Kristene Gedye, Alex Grinberg, Nicolas Lopez-Villalobos
Biofilm formation is of growing concern in human and animal health. However, it is still unclear how biofilms are related to mastitis infections in dairy cattle. In this study, a comparison between two tests for biofilm formation and the association between biofilm and the presence of genes associated with biofilm formation were investigated for 92 Staphylococcus aureus isolates from clinical mastitis cases. Congo red agar (CRA) and microtitre test assay (MTA) in vitro phenotypic tests were used to evaluate biofilm formation...
January 19, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29280751/different-genotypes-of-adhesion-operon-genes-in-staphylococcus-epidermidis-isolates-from-various-ocular-infections
#10
Mehrnoush Sharifinejad, Narjes Shokatpour, Farshad Farnaghi, Zohreh Abedinyfar, Fahimeh Asadi Amoli, Farahnoosh Doustdar
BACKGROUND: Staphylococcus epidermidis is one of the common causes of bacterial keratitis and post-operation infections. One of the most important virulence factors of S. epidermidis is biofilm formation. Poly-N-acetylglucosamine (PNAG) production is critical for biofilm formation in S. epidermidis. The intercellular adhesion (ica) operon is formed by icaA, icaD, icaB, and icaC genes, which participate in the biosynthesis of PNAG. Strains of S. epidermidis from different infections show different genotypes in relation to adhesion operon genes...
December 26, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29279888/prevalence-of-systemic-atherosclerosis-burdens-and-overlapping-stroke-etiologies-and-their-associations-with-long-term-vascular-prognosis-in-stroke-with-intracranial-atherosclerotic-disease
#11
Takao Hoshino, Leila Sissani, Julien Labreuche, Gregory Ducrocq, Philippa C Lavallée, Elena Meseguer, Céline Guidoux, Lucie Cabrejo, Cristina Hobeanu, Fernando Gongora-Rivera, Pierre-Jean Touboul, Philippe Gabriel Steg, Pierre Amarenco
Importance: Patients who have experienced stroke with intracranial atherosclerotic disease (ICAD) may also have concomitant atherosclerosis in different arterial beds and other possible causes for ischemic stroke. However, little is known about the frequency and prognostic effect of such overlapping diseases. Objectives: To describe the prevalence of systemic atherosclerotic burdens and overlapping stroke etiologies and their contributions to long-term prognoses among patients who have experienced stroke with ICAD...
February 1, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29233683/caspase-mediated-cleavage-of-x-ray-repair-cross-complementing-group-4-promotes-apoptosis-by-enhancing-nuclear-translocation-of-caspase-activated-dnase
#12
Yumi Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi Matsui, Ryo Sakasai, Mitsumasa Hashimoto, Yasuhito Ishigaki, Yoshihisa Matsumoto, Kuniyoshi Iwabuchi
X-ray repair cross-complementing group 4 (XRCC4), a repair protein for DNA double-strand breaks, is cleaved by caspases during apoptosis. In this study, we examined the role of XRCC4 in apoptosis. Cell lines, derived from XRCC4-deficient M10 mouse lymphoma cells and stably expressing wild-type XRCC4 or caspase-resistant XRCC4, were established and treated with staurosporine (STS) to induce apoptosis. In STS-induced apoptosis, expression of wild-type, but not caspase-resistant, XRCC4 in XRCC4-deficient cells enhanced oligonucleosomal DNA fragmentation and the appearance of TUNEL-positive cells by promoting nuclear translocation of caspase-activated DNase (CAD), a major nuclease for oligonucleosomal DNA fragmentation...
January 15, 2018: Experimental Cell Research
https://www.readbyqxmd.com/read/29178841/multiresistant-st59-sccmec-iv-t437-clone-with-strong-biofilm-forming-capacity-was-identified-predominantly-in-mrsa-isolated-from-chinese-children
#13
Xin Yang, Suyun Qian, Kaihu Yao, Lijuan Wang, Yingchao Liu, Fang Dong, Wenqi Song, Jinghui Zhen, Wei Zhou, Hong Xu, Hongyan Zheng, Wenting Li
BACKGROUND: This study aimed to investigate the clinical and molecular epidemiology and biofilm formation of Staphylococcus aureus (SA) isolated from pediatricians in China. METHODS: SA strains were isolated from Beijing Children's hospital from February 2016 to January 2017. Isolates were typed by multilocus sequence typing (MLST), spa and SCCmec typing (for Methicillin-resistant SA [MRSA] only). Antimicrobial susceptibility testing was performed by agar dilution method except sulphamethoxazole/trimethoprim (E-test method)...
November 25, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29147634/intracranial-ischemic-infarct-due-to-blunt-force-trauma-in-a-high-school-football-player
#14
Brandon I Esianor, Ali S Haider, Margaret I Engelhardt, Tijani Osumah, Steven Vayalumkal, Richa Thakur, Dean Leonard, Jeffrey Haithcock, Kennith F Layton
Ischemic stroke is an uncommon cause of death among teenagers and young adults; however, the etiologies differ when compared to ischemic strokes in older individuals. Large-vessel atherosclerosis and small-vessel disease causing ischemic stroke are rare for the teenage population, while cervicocerebral arterial dissections account for up to 20% of ischemic strokes. Here, we present the case of a 16-year-old male who developed internal carotid artery dissection (ICAD) after a head injury and subsequently developed ischemic stroke and seizures...
September 7, 2017: Curēus
https://www.readbyqxmd.com/read/29146499/antimicrobial-resistance-and-virulence-genes-profiling-of-methicillin-resistant-staphylococcus-aureus-isolates-in-a-burn-center-a-5-year-study
#15
Bei Jiang, Supeng Yin, Bo You, Yali Gong, Guangtao Huang, Zichen Yang, Yulong Zhang, Yu Chen, Jing Chen, Zhiqiang Yuan, Xiaomei Hu, Yizhi Peng
Methicillin-resistant S. aureus (MRSA) has attracted more and more attention in recent years, especially in burn medical centers. Here we conducted a 5-year period study to evaluate the MRSA infection in our burn center. The staphylococcal chromosomal cassette mec (SCCmec) typing, antimicrobials susceptibility and virulence profiles were also performed among the MRSA isolates. Of the 259 S. aureus isolates, 239 (92.28%) isolates were identified as MRSA. A decreased trend of MRSA isolation rate over time was found (P = 0...
January 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29102741/physics-aspects-of-the-papillon-technique-five-decades-later
#16
Li Heng Liang, Nada Tomic, Te Vuong, Saad Aldelaijan, Hamed Bekerat, Francois DeBlois, Jan Seuntjens, Slobodan Devic
PURPOSE: The Papillon technique using 50-kVp soft X-rays to treat rectal adenocarcinomas was developed and clinically implemented in the 1960s. We describe differences between accurate dosimetry and clinical implementation of this technique that is extending from its very inception to date. METHODS AND MATERIALS: A renaissance of the Papillon technique occurred with two recently introduced 50-kVp systems: Papillon+ by Ariane and a custom-made rectal applicator (consisting of a surface applicator inserted into a proctoscope) by iCAD's Xoft Axxent Electronic Brachytherapy (eBT) System (iCad, Inc...
January 2018: Brachytherapy
https://www.readbyqxmd.com/read/29094154/racial-differences-in-prevalence-and-risk-for-intracranial-atherosclerosis-in-a-us-community-based-population
#17
Ye Qiao, Fareed K Suri, Yiyi Zhang, Li Liu, Rebecca Gottesman, Alvaro Alonso, Eliseo Guallar, Bruce A Wasserman
Importance: Intracranial atherosclerotic disease (ICAD) is an important cause of stroke; however, little is known about racial differences in ICAD prevalence and its risk factors. Objective: To determine racial differences in ICAD prevalence and the risk factors (both midlife and concurrent) associated with its development in a large, US community-based cohort. Design, Setting, and Participants: Analysis of 1752 black and white participants recruited from the Atherosclerosis Risk in Communities (ARIC) cohort study who underwent 3-dimensional intracranial vessel wall magnetic resonance imaging from October 18, 2011 to December 30, 2013; data analysis was performed from October 18, 2011 to May 13, 2015...
December 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29027868/posttraumatic-complications-in-pediatric-skull-fracture-dural-sinus-thrombosis-arterial-dissection-and-cerebrospinal-fluid-leakage
#18
Adedamola Adepoju, Matthew A Adamo
OBJECTIVE Skull fracture is associated with several intracranial injuries. The object of this study was to determine the rate of fracture associated with venous thrombosis, intracranial arterial dissection (ICAD), and cerebrospinal fluid (CSF) leakage in pediatric patients. Further, the authors aimed to highlight the features of pediatric skull fracture that predict poor neurological outcomes. METHOD In this retrospective study, the authors evaluated the records of 258 pediatric patients who had incurred a traumatic skull fracture in the period from 2009 to 2015...
December 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28993906/antiangiogenesis-and-medical-therapy-failure-in-intracranial-atherosclerosis
#19
Nestor R Gonzalez, Raymond Liou, Florian Kurth, Hao Jiang, Jeffrey Saver
Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide and the one with the worst prognosis. In this study, we assessed the hypothesis that the balance of circulating pro- and antiangiogenic factors plays a role in the evolution of the disease and can be used as a potential marker for the disease course and a target for treatment. Seventy-four patients with severe ICAD were enrolled in this prospective observational study, medically optimized, and followed for 6 months...
February 2018: Angiogenesis
https://www.readbyqxmd.com/read/28987852/factors-associated-with-90-day-outcomes-of-patients-with-acute-posterior-circulation-stroke-treated-by-mechanical-thrombectomy
#20
Gang Luo, Dapeng Mo, Xu Tong, David S Liebeskind, Ligang Song, Ning Ma, Feng Gao, Xuan Sun, Xuelei Zhang, Bo Wang, Baixue Jia, Alejandro Fernandez-Escobar, Zhongrong Miao
BACKGROUND AND OBJECTIVE: Early recanalization of acute posterior circulation stroke caused by large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. This study investigated the prognostic factors of acute posterior circulation stroke caused by large intracranial arterial occlusion when treated with stent-retriever thrombectomy. METHODS: A total of 69 patients from March 2012 to November 2016 were included in the study...
January 2018: World Neurosurgery
keyword
keyword
112923
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"