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https://www.readbyqxmd.com/read/29147634/intracranial-ischemic-infarct-due-to-blunt-force-trauma-in-a-high-school-football-player
#1
Brandon I Esianor, Ali S Haider, Margaret I Engelhardt, Tijani Osumah, Steven Vayalumkal, Richa Thakur, Dean Leonard, Jeffrey Haithcock, Kennith F Layton
Ischemic stroke is an uncommon cause of death among teenagers and young adults; however, the etiologies differ when compared to ischemic strokes in older individuals. Large-vessel atherosclerosis and small-vessel disease causing ischemic stroke are rare for the teenage population, while cervicocerebral arterial dissections account for up to 20% of ischemic strokes. Here, we present the case of a 16-year-old male who developed internal carotid artery dissection (ICAD) after a head injury and subsequently developed ischemic stroke and seizures...
September 7, 2017: Curēus
https://www.readbyqxmd.com/read/29146499/antimicrobial-resistance-and-virulence-genes-profiling-of-methicillin-resistant-staphylococcus-aureus-isolates-in-a-burn-center-a-5-year-study
#2
Bei Jiang, Supeng Yin, Bo You, Yali Gong, Guangtao Huang, Zichen Yang, Yulong Zhang, Yu Chen, Jing Chen, Zhiqiang Yuan, Xiaomei Hu, Yizhi Peng
Methicillin-resistant S. aureus (MRSA) has attracted more and more attention in recent years, especially in burn medical centers. Here we conducted a 5-year period study to evaluate the MRSA infection in our burn center. The staphylococcal chromosomal cassette mec (SCCmec) typing, antimicrobials susceptibility and virulence profiles were also performed among the MRSA isolates. Of the 259 S. aureus isolates, 239 (92.28%) isolates were identified as MRSA. A decreased trend of MRSA isolation rate over time was found (P = 0...
November 13, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29102741/physics-aspects-of-the-papillon-technique-five-decades-later
#3
Li Heng Liang, Nada Tomic, Te Vuong, Saad Aldelaijan, Hamed Bekerat, Francois DeBlois, Jan Seuntjens, Slobodan Devic
PURPOSE: The Papillon technique using 50-kVp soft X-rays to treat rectal adenocarcinomas was developed and clinically implemented in the 1960s. We describe differences between accurate dosimetry and clinical implementation of this technique that is extending from its very inception to date. METHODS AND MATERIALS: A renaissance of the Papillon technique occurred with two recently introduced 50-kVp systems: Papillon+ by Ariane and a custom-made rectal applicator (consisting of a surface applicator inserted into a proctoscope) by iCAD's Xoft Axxent Electronic Brachytherapy (eBT) System (iCad, Inc...
November 1, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29094154/racial-differences-in-prevalence-and-risk-for-intracranial-atherosclerosis-in-a-us-community-based-population
#4
Ye Qiao, Fareed K Suri, Yiyi Zhang, Li Liu, Rebecca Gottesman, Alvaro Alonso, Eliseo Guallar, Bruce A Wasserman
Importance: Intracranial atherosclerotic disease (ICAD) is an important cause of stroke; however, little is known about racial differences in ICAD prevalence and its risk factors. Objective: To determine racial differences in ICAD prevalence and the risk factors (both midlife and concurrent) associated with its development in a large, US community-based cohort. Design, Setting, and Participants: Analysis of 1752 black and white participants recruited from the Atherosclerosis Risk in Communities (ARIC) cohort study who underwent 3-dimensional intracranial vessel wall magnetic resonance imaging from October 18, 2011 to December 30, 2013; data analysis was performed from October 18, 2011 to May 13, 2015...
November 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29027868/posttraumatic-complications-in-pediatric-skull-fracture-dural-sinus-thrombosis-arterial-dissection-and-cerebrospinal-fluid-leakage
#5
Adedamola Adepoju, Matthew A Adamo
OBJECTIVE Skull fracture is associated with several intracranial injuries. The object of this study was to determine the rate of fracture associated with venous thrombosis, intracranial arterial dissection (ICAD), and cerebrospinal fluid (CSF) leakage in pediatric patients. Further, the authors aimed to highlight the features of pediatric skull fracture that predict poor neurological outcomes. METHOD In this retrospective study, the authors evaluated the records of 258 pediatric patients who had incurred a traumatic skull fracture in the period from 2009 to 2015...
October 13, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28993906/antiangiogenesis-and-medical-therapy-failure-in-intracranial-atherosclerosis
#6
Nestor R Gonzalez, Raymond Liou, Florian Kurth, Hao Jiang, Jeffrey Saver
Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide and the one with the worst prognosis. In this study, we assessed the hypothesis that the balance of circulating pro- and antiangiogenic factors plays a role in the evolution of the disease and can be used as a potential marker for the disease course and a target for treatment. Seventy-four patients with severe ICAD were enrolled in this prospective observational study, medically optimized, and followed for 6 months...
October 9, 2017: Angiogenesis
https://www.readbyqxmd.com/read/28987852/factors-associated-with-90-day-outcomes-of-patients-with-acute-posterior-circulation-stroke-treated-by-mechnical-thrombectomy
#7
Gang Luo, Dapeng Mo, Xu Tong, David S Liebeskind, Ligang Song, Ning Ma, Feng Gao, Xuan Sun, Xuelei Zhang, Bo Wang, Baixue Jia, Alejandro Fernandez-Escobar, Zhongrong Miao
BACKGROUND AND PURPOSE: Early recanalization of acute posterior circulation stroke due to large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. The study investigated the prognostic factors of acute posterior circulation stroke due to large intracranial arterial occlusion when treated withstent retriever thrombectomy. METHODS: A total of 69 patients from March 2012 to November 2016 were included in the study...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28899572/hypoglossal-nerve-palsy-in-the-course-of-dissection-of-the-internal-carotid-arteries-case-reports
#8
Magdalena Torbus-Paluszczak, Sebastian Mucha, Maciej Wawrzyńczyk, Krystyna Pierzchała, Wojciech Bartman, Monika Adamczyk-Sowa
Internal carotid artery dissection (ICAD) has become an increasingly recognized cause of cerebrovascular accidents in young and middle-aged patients. We report 2 cases of hypoglossal nerve palsy in the course of dissection of the internal carotid arteries. The first patient was admitted to the Department of Neurology due to swallowing difficulty, speech articulation disorders and numbness of the right half of the tongue for 4 weeks. Extracranial vessel ultrasound (US) and transcranial colour Doppler (TCD) visualized thrombus causing occlusion of the right internal carotid artery (RICA)...
August 30, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28892140/biofilm-formation-and-its-relationship-with-the-molecular-characteristics-of-food-related-methicillin-resistant-staphylococcus-aureus-mrsa
#9
Alberto Vergara, Giovanni Normanno, Pierluigi Di Ciccio, Francesca Pedonese, Roberta Nuvoloni, Antonio Parisi, Gianfranco Santagada, Angelo Colagiorgi, Emanuela Zanardi, Sergio Ghidini, Adriana Ianieri
The capability to produce biofilm is an important persistence and dissemination mechanism of some foodborne bacteria. This paper investigates the relationship between some molecular characteristics (SCCmec, ST, spa-type, agr-type, cna, sarA, icaA, icaD, clfA, fnbA, fnbB, hla, hlb) of 22 food-related methicillin-resistant Staphylococcus aureus (MRSA) strains and their ability to form biofilm on stainless steel and polystyrene. Five (22.7%, 5/22) strains were able to synthesize biofilm on polystyrene, and one of these (4...
October 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28815313/epidemiology-and-cerebrovascular-events-related-to-cervical-and-intracranial-arteries-dissection-the-experience-of-the-city-of-pisa
#10
N Giannini, L Ulivi, M Maccarrone, V Montano, G Orlandi, E Ferrari, C Cravcenco, U Bonuccelli, M Mancuso
Spontaneous dissection of cervical arteries (sCAD) is a major cause of ischemic stroke in young patients, with an incidence varying from 1.7 to 3/100,000/year for extracranial internal carotid artery (ICAD) and 1 to 1.9/100,000/year for extracranial vertebral artery (VAD). Reliable epidemiological data on stroke incidence related to sCAD are scarce in Italy. This study aims to evaluate the incidence, clinical features, and outcome of cerebrovascular events related to sCAD and spontaneous intracranial arteries dissections (sIAD) in the city of Pisa (Italy)...
November 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28783429/characterization-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-cc398-and-mecc-positive-cc130-from-zoo-animals-in-the-united-kingdom
#11
Alessio Bortolami, Ranieri Verin, Julian Chantrey, Michela Corrò, Ian Ashpole, Javier Lopez, Dorina Timofte
Little is known about the characteristics and diseases associated with methicillin-resistant Staphylococcus aureus (MRSA) in nondomestic animals. Four presumptive MRSA isolates, obtained from clinical (n = 3) and surveillance specimens (n = 1) from dwarf (Helogale parvula) and yellow mongooses (Cynictis penicillata) from a United Kingdom zoo, were analyzed by PCR for detection of mecA and mecC-mediated methicillin resistance, and virulence genes. Isolates were genotyped by multilocus sequence typing (MLST) and staphylococcal cassette chromosome mec (SCCmec) and spa sequence typing...
October 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28782888/physical-activity-and-sedentary-time-associations-with-metabolic-health-across-weight-statuses-in-children-and-adolescents
#12
Nicholas Kuzik, Valerie Carson, Lars Bo Andersen, Luís B Sardinha, Anders Grøntved, Bjørge Herman Hansen, Ulf Ekelund
OBJECTIVE: The aim of this study was to examine the prevalence of metabolic health across weight statuses and the associations of physical activity and sedentary time within and across metabolic health-weight status groups. METHODS: Six studies (n = 4,581) from the International Children's Accelerometry Database were used. Sedentary time, light physical activity, and moderate to vigorous physical activity (MVPA) were accelerometer derived. Individuals were classified with normal weight (NW), overweight, or obesity...
August 7, 2017: Obesity
https://www.readbyqxmd.com/read/28765481/carotid-dissection-presenting-as-a-prolonged-cluster-like-headache-in-a-patient-with-episodic-cluster-headache
#13
Ahmed Mohamed Elhfnawy, László Solymosi, Claudia Sommer
We present a patient with known episodic cluster headache, who presented with cluster-like headache in the course of internal carotid artery dissection (ICAD) and discuss possible pathophysiological links between the two diseases. It is well known that cluster-like headache could be the presenting symptom of ICAD. However, ICAD occurring in a patient with a known episodic cluster headache was only once previously described. In the end of the manuscript, we propose red flags to help clinicians differentiate between primary cluster headache and cluster-like attacks masking underlying ICAD...
July 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28757274/phenotypic-and-genotypic-characterization-of-biofilm-formation-among-staphylococcus-aureus-isolates-from-clinical-specimens-an-atomic-force-microscopic-afm-study
#14
Pelin Aslani Menareh Bazari, Sahar Honarmand Jahromy, Shohreh Zare Karizi
INTRODUCTION: Staphylococcus aureus is a major cause of nosocomial infections. Biofilm formation is an important factor for bacterial pathogenesis. Its mechanisms are complex and include of many genes depends on expression of icaADBC operon involved in the synthesis of a polysaccharide intercellular adhesion. AIM: The aim of study was to investigate biofilm forming ability of Staphylococcus aureus strains by phenotypic and genotypic methods. Also Atomic Force microscope (AFM) was used to visualize biofilm formation...
July 27, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28710384/prospective-evaluation-of-the-diagnostic-value-of-plasma-apelin-12-levels-for-differentiating-patients-with-moyamoya-and-intracranial-atherosclerotic-diseases
#15
Wei Hu, Wan Jiang, Li Ye, Yanghua Tian, Bing Shen, Kai Wang
Patients with moyamoya disease (MMD) or intracranial atherosclerotic disease (ICAD) experience similar cerebral ischaemic events. However, MMD patients show greater angiogenesis and arteriogenesis, which play crucial roles in collateral circulation development to enhance clinical prognosis and outcome. Apelins have been associated with angiogenesis and arteriogenesis. Therefore, the aim of the present study was to determine whether apelin levels were higher in patients with MMD than in patients with ICAD or in healthy controls...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28707667/-the-activity-of-proapoptotic-genes-increases-after-renal-ischemia-reperfusion
#16
O I Kit, D I Vodolazhsky, S N Dimitriadi, D S Kutilin, N N Timoshkina, E N Gudueva, E M Frantsiyants
According to the World Health Organization, pathologies associated with ischemia/reperfusion occupy the leading position in the structure of mortality. The efficiency of localized kidney cancer surgery is limited by the damaging effects of prolonged warm ischemia and reperfusion. Ischemia/reperfusion damage to renal tissue may be related to changes in the expression profiles of pro- and antiapoptotic genes. Here, we have presented the longitudinal expression profiles of apoptosis-related genes in tissues of left and right (intact) kidneys of male rats exposed to unilateral ischemia followed by reperfusion...
May 2017: Molekuliarnaia Biologiia
https://www.readbyqxmd.com/read/28702117/balloon-angioplasty-for-intracranial-atherosclerotic-disease-a-multicenter-study
#17
Lakshmi Sudha Prasanna Karanam, Mukesh Sharma, Anand Alurkar, Sridhar Reddy Baddam, Vijaya Pamidimukkala, Raghavasarma Polavarapu
AIM: To evaluate the role and efficacy of the balloon angioplasty in intracranial atherosclerotic disease (ICAD) in patients who presented with acute stroke due to vessel occlusion and in patients with symptomatic disease despite optimum medical management. METHODS: From 2013 to 2016, a total of 39 patients (24 males and 15 females with a mean age of 64.5 years) underwent balloon angioplasty over a period of 2 years and 8 months in three different institutions in India...
June 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/28698870/current-status-and-future-perspective-of-stenting-for-symptomatic-intracranial-atherosclerotic-disease-a-meta-analysis
#18
REVIEW
Zhong-Hao Li, Zhen-Hua Zhou, Xian-Jin Zhu, Wei Liu, Ya-Wen Chen, Zi-Yao Chen, Zun-Jing Liu
The aim of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty and stenting (PTAS) for intracranial atherosclerotic disease (ICAD) by conducting a meta-analysis. Two independent observers searched PubMed, EMBASE, and Cochrane Library for relevant studies up to 31 December 2016. A meta-analysis was conducted using Review Manager 5.3. Three studies involving 581 cases were included. The meta-analysis indicated that any stroke (RR = 3.13; 95% CI: 1.80-5.42), ischemic stroke (RR = 2...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28571985/host-pathogen-interactions-in-bovine-mammary-epithelial-cells-and-hela-cells-by-staphylococcus-aureus-isolated-from-subclinical-bovine-mastitis
#19
Ivana G Castilho, Stéfani Thais Alves Dantas, Hélio Langoni, João P Araújo, Ary Fernandes, Fernanda C L Alvarenga, Leandro Maia, Didier Q Cagnini, Vera L M Rall
Staphylococcus aureus is a common pathogen that causes subclinical bovine mastitis due to several virulence factors. In this study, we analyzed S. aureus isolates collected from the milk of cows with subclinical mastitis that had 8 possible combinations of bap, icaA, and icaD genes, to determine their capacity to produce biofilm on biotic (bovine primary mammary epithelial cells and HeLa cells) and abiotic (polystyrene microplates) surfaces, and their ability to adhere to and invade these cells. We also characterized isolates for microbial surface components recognizing adhesive matrix molecules (MSCRAMM) and agr genes, and for their susceptibility to cefquinome sulfate in the presence of biofilm...
May 29, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28558747/weather-and-children-s-physical-activity-how-and-why-do-relationships-vary-between-countries
#20
Flo Harrison, Anna Goodman, Esther M F van Sluijs, Lars Bo Andersen, Greet Cardon, Rachel Davey, Kathleen F Janz, Susi Kriemler, Lynn Molloy, Angie S Page, Russ Pate, Jardena J Puder, Luis B Sardinha, Anna Timperio, Niels Wedderkopp, Andy P Jones
BACKGROUND: Globally most children do not engage in enough physical activity. Day length and weather conditions have been identified as determinants of physical activity, although how they may be overcome as barriers is not clear. We aim to examine if and how relationships between children's physical activity and weather and day length vary between countries and identify settings in which children were better able to maintain activity levels given the weather conditions they experienced...
May 30, 2017: International Journal of Behavioral Nutrition and Physical Activity
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