Yasunori Iwata, Yusuke Nakade, Masashi Kinoshita, Hemragul Sabit, Riho Nakajima, Kengo Furuichi, Masashi Mita, Maiko Nakane, Norihiko Sakai, Shinji Kitajima, Tadashi Toyama, Taro Miyagawa, Akinori Hara, Miho Shimizu, Kouichi Sato, Megumi Oshima, Shiori Nakagawa, Yuta Yamamura, Hisayuki Ogura, Yoshitaka Koshino, Mitsutoshi Nakada, Takashi Wada
INTRODUCTION: The number of patients with chronic kidney disease (CKD) is increasing worldwide. Cognitive impairment is one of the comorbidities of CKD. With the increased number of aged population, novel biomarkers of impaired cognitive function are required. Intra-body profile of amino acid (AA) is reportedly altered in patients with CKD. Although some AAs act as neurotransmitters in the brain, it is not clear whether altered AA profile are associated with cognitive function in patients with CKD...
April 2023: Kidney Diseases