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https://www.readbyqxmd.com/read/28628619/south-african-ebola-diagnostic-response-in-sierra-leone-a-modular-high-biosafety-field-laboratory
#1
Janusz T Paweska, Petrus Jansen van Vuren, Gunther H Meier, Chantel le Roux, Ousman S Conteh, Alan Kemp, Cardia Fourie, Prabha Naidoo, Serisha Naicker, Phumza Ohaebosim, Nadia Storm, Orienka Hellferscee, Lisa K Ming Sun, Busisiwe Mogodi, Nishi Prabdial-Sing, Desiree du Plessis, Deidre Greyling, Shayne Loubser, Mark Goosen, Stewart D McCulloch, Terence P Scott, Alexandra Moerdyk, Wesley Dlamini, Kelfala Konneh, Idrissa L Kamara, Dauda Sowa, Samuel Sorie, Brima Kargbo, Shabir A Madhi
BACKGROUND: In August 2014, the National Institute for Communicable Diseases (NICD) in South Africa established a modular high-biosafety field Ebola diagnostic laboratory (SA FEDL) near Freetown, Sierra Leone in response to the rapidly increasing number of Ebola virus disease (EVD) cases. METHODS AND FINDINGS: The SA FEDL operated in the Western Area of Sierra Leone, which remained a "hotspot" of the EVD epidemic for months. The FEDL was the only diagnostic capacity available to respond to the overwhelming demand for rapid EVD laboratory diagnosis for several weeks in the initial stages of the EVD crisis in the capital of Sierra Leone...
June 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28628441/novel-retinal-lesion-in-ebola-survivors-sierra-leone-2016
#2
Paul J Steptoe, Janet T Scott, Julia M Baxter, Craig K Parkes, Rahul Dwivedi, Gabriela Czanner, Matthew J Vandy, Fayiah Momorie, Alimamy D Fornah, Patrick Komba, Jade Richards, Foday Sahr, Nicholas A V Beare, Malcolm G Semple
We conducted a case-control study in Freetown, Sierra Leone, to investigate ocular signs in Ebola virus disease (EVD) survivors. A total of 82 EVD survivors with ocular symptoms and 105 controls from asymptomatic civilian and military personnel and symptomatic eye clinic attendees underwent ophthalmic examination, including widefield retinal imaging. Snellen visual acuity was <6/7.5 in 75.6% (97.5% CI 63%-85.7%) of EVD survivors and 75.5% (97.5% CI 59.1%-87.9%) of controls. Unilateral white cataracts were present in 7...
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28619418/corrigendum-to-there-s-no-app-for-that-assessing-the-impact-of-mhealth-on-the-supervision-motivation-engagement-and-satisfaction-of-community-health-workers-in-sierra-leone-annals-of-global-health-82-2016-936-949
#3
Frédérique Vallières, Eilish McAuliffe, Bianca van Bavel, P J Wall, Augustine Trye
No abstract text is available yet for this article.
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28611015/too-far-to-care-measuring-public-attention-and-fear-for-ebola-using-twitter
#4
Liza Gg van Lent, Hande Sungur, Florian A Kunneman, Bob van de Velde, Enny Das
BACKGROUND: In 2014, the world was startled by a sudden outbreak of Ebola. Although Ebola infections and deaths occurred almost exclusively in Guinea, Sierra Leone, and Liberia, few potential Western cases, in particular, caused a great stir among the public in Western countries. OBJECTIVE: This study builds on the construal level theory to examine the relationship between psychological distance to an epidemic and public attention and sentiment expressed on Twitter...
June 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28610609/estimation-of-basic-reproduction-number-of-the-middle-east-respiratory-syndrome-coronavirus-mers-cov-during-the-outbreak-in-south-korea-2015
#5
Hyuk-Jun Chang
BACKGROUND: In South Korea, an outbreak of Middle East respiratory syndrome (MERS) occurred in 2015. It was the second largest MERS outbreak. As a result of the outbreak in South Korea, 186 infections were reported, and 36 patients died. At least 16,693 people were isolated with suspicious symptoms. This paper estimates the basic reproduction number of the MERS coronavirus (CoV), using data on the spread of MERS in South Korea. METHODS: The basic reproduction number of an epidemic is defined as the average number of secondary cases that an infected subject produces over its infectious period in a susceptible and uninfected population...
June 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28606162/how-behavioural-science-can-contribute-to-health-partnerships-the-case-of-the-change-exchange
#6
REVIEW
Lucie M T Byrne-Davis, Eleanor R Bull, Amy Burton, Nimarta Dharni, Fiona Gillison, Wendy Maltinsky, Corina Mason, Nisha Sharma, Christopher J Armitage, Marie Johnston, Ged J Byrne, Jo K Hart
BACKGROUND: Health partnerships often use health professional training to change practice with the aim of improving quality of care. Interventions to change practice can learn from behavioural science and focus not only on improving the competence and capability of health professionals but also their opportunity and motivation to make changes in practice. We describe a project that used behavioural scientist volunteers to enable health partnerships to understand and use the theories, techniques and assessments of behavioural science...
June 12, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28588978/improving-ebola-infection-prevention-and-control-in-primary-healthcare-facilities-in-sierra-leone-a-single-group-pretest-post-test-mixed-methods-study
#7
Ruwan Ratnayake, Lara S Ho, Rashid Ansumana, Hannah Brown, Matthias Borchert, Laura Miller, Thomas Kratz, Shannon A McMahon, Foday Sahr
BACKGROUND: Accomplishing infection prevention and control (IPC) in health facilities in Sub-Saharan Africa is challenging. Owing to poor IPC, healthcare workers (HCWs) were frequently infected during Sierra Leone's Ebola epidemic. In late 2014, IPC was rapidly and nationally scaled up. We carried out workshops in sampled facilities to further improve adherence to IPC. We investigated HCW experiences and observed practice gaps, before and after the workshops. METHODS: We conducted an uncontrolled, before and after, mixed-methods study in eight health facilities in Bo and Kenema Districts during December 2014 and January 2015...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588973/responding-to-ever-changing-epidemiological-dynamics-of-ebola-virus-disease
#8
Yuki Maehira, Yohei Kurosaki, Tomoya Saito, Jiro Yasuda, Masayoshi Tarui, Denis J M Malvy, Tsutomu Takeuchi
With the incidence and mortality rates of Ebola virus disease (EVD) in Guinea, Liberia and Sierra Leone now at zero and reports of the largest and most complex EVD outbreak in history no longer on the front pages of newspapers worldwide, the urgency of that crisis seems to have subsided. During this lull after the storm and before the next one, the international community needs to engage in a 'lessons-learned' exercise with respect to our collective scientific, clinical and public health preparedness. This engagement must identify pragmatic, innovative mechanisms at multinational, national and community levels that allow research and development of next generation diagnostics and therapeutics, the safe and effective practice of medicine, and the maintenance of public health to keep pace with the rapid epidemiological dynamics of EVD and other deadly infectious diseases...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588965/long-shadow-of-fear-in-an-epidemic-fearonomic-effects-of-ebola-on-the-private-sector-in-nigeria
#9
Sulzhan Bali, Kearsley A Stewart, Muhammad Ali Pate
BACKGROUND: The already significant impact of the Ebola epidemic on Guinea, Liberia and Sierra Leone, was worsened by a fear of contagion that aggravated the health crisis. However, in contrast to other Ebola-affected countries, Nigeria fared significantly better due to its swift containment of the disease. The objective of our study was to describe the impact of Ebola on the Nigerian private sector. This paper introduces and defines the term fearonomic effect as the direct and indirect economic effects of both misinformation as well as fear-induced aversion behaviour, exhibited by individuals, organisations or countries during an outbreak or an epidemic...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588963/-once-there-is-life-there-is-hope-ebola-survivors-experiences-behaviours-and-attitudes-in-sierra-leone-2015
#10
Emilie Karafillakis, Mohamed F Jalloh, Azizeh Nuriddin, Heidi J Larson, Jimmy Whitworth, Shelley Lees, Kathy M Hageman, Paul Sengeh, Mohammad B Jalloh, Rebecca Bunnell, Dianna D Carroll, Oliver Morgan
BACKGROUND: In Sierra Leone, over 4000 individuals survived Ebola since the outbreak began in 2014. Because Ebola survivorship was largely unprecedented prior to this outbreak, little is known about survivor experiences during and post illness. METHODS: To assess survivors' experiences and attitudes related to Ebola, 28 in-depth interviews and short quantitative surveys with survivors from all four geographic regions of Sierra Leone were conducted in May 2015. RESULTS: Survivor experiences, emotions and attitudes changed over time as they moved from disease onset to treatment, discharge and life post-discharge...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588954/-women-and-babies-are-dying-but-not-of-ebola-the-effect-of-the-ebola-virus-epidemic-on-the-availability-uptake-and-outcomes-of-maternal-and-newborn-health-services-in-sierra-leone
#11
Susan A Jones, Somasundari Gopalakrishnan, Charles A Ameh, Sarah White, Nynke R van den Broek
BACKGROUND: We sought to determine the impact of the Ebola virus epidemic on the availability, uptake and outcome of routine maternity services in Sierra Leone. METHODS: The number of antenatal and postnatal visits, institutional births, availability of emergency obstetric care (EmOC), maternal deaths and stillbirths were assessed by month, by districts and by level of healthcare for 10 months during, and 12 months prior to, the Ebola virus disease (EVD) epidemic...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28584177/structural-drivers-of-vulnerability-to-zoonotic-disease-in-africa
#12
Vupenyu Dzingirai, Salome Bukachi, Melissa Leach, Lindiwe Mangwanya, Ian Scoones, Annie Wilkinson
This paper argues that addressing the underlying structural drivers of disease vulnerability is essential for a 'One Health' approach to tackling zoonotic diseases in Africa. Through three case studies-trypanosomiasis in Zimbabwe, Ebola and Lassa fever in Sierra Leone and Rift Valley fever in Kenya-we show how political interests, commercial investments and conflict and securitization all generate patterns of vulnerability, reshaping the political ecology of disease landscapes, influencing traditional coping mechanisms and affecting health service provision and outbreak responses...
July 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28584171/local-disease-ecosystem-livelihood-dynamics-reflections-from-comparative-case-studies-in-africa
#13
Melissa Leach, Bernard Bett, M Said, Salome Bukachi, Rosemary Sang, Neil Anderson, Noreen Machila, Joanna Kuleszo, Kathryn Schaten, Vupenyu Dzingirai, Lindiwe Mangwanya, Yaa Ntiamoa-Baidu, Elaine Lawson, Kofi Amponsah-Mensah, Lina M Moses, Annie Wilkinson, Donald S Grant, James Koninga
This article explores the implications for human health of local interactions between disease, ecosystems and livelihoods. Five interdisciplinary case studies addressed zoonotic diseases in African settings: Rift Valley fever (RVF) in Kenya, human African trypanosomiasis in Zambia and Zimbabwe, Lassa fever in Sierra Leone and henipaviruses in Ghana. Each explored how ecological changes and human-ecosystem interactions affect pathogen dynamics and hence the likelihood of zoonotic spillover and transmission, and how socially differentiated peoples' interactions with ecosystems and animals affect their exposure to disease...
July 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28583834/intervention-to-improve-awareness-of-the-risk-factors-for-osteonecrosis-of-the-jaw-in-patients-under-treatment-with-bisphosponates-randomised-clinical-trial
#14
Lucía García-Martínez, Rubén Martín-Payo, Alejandro Pelaz-García, Matilde Sierra-Vega, Luis Manuel Junquera-Gutiérrez
PURPOSE: To evaluate the effectiveness of a health education programme on knowledge and reduction of the risk factors for bisphosphonate-related osteonecrosis of the jaw. METHODS: An experimental study control group without intervention was performed with 60 subjects who had started treatment with bisphosphonates in the University Hospital of León from October to December 2014. Patients in the experimental group received a structured education intervention in two sessions...
June 2, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28570857/-even-when-you-are-afraid-you-stay-provision-of-maternity-care-during-the-ebola-virus-epidemic-a-qualitative-study
#15
Susan Jones, Betty Sam, Florence Bull, Steven Bagie Pieh, Jaki Lambert, Florence Mgawadere, Somasundari Gopalakrishnan, Charles A Ameh, Nynke van den Broek
OBJECTIVE: to explore nurse-midwives understanding of their role in and ability to continue to provide routine and emergency maternity services during the time of the Ebola virus disease epidemic in Sierra Leone. DESIGN: a hermenuetic phenomenological approach was used to discover the lived experiences of nurse-midwives through 66 face to face interviews. Following verbatim transcription, an iterative approach to data analysis was adopted using framework analysis to discover the essence of the lived experience...
May 22, 2017: Midwifery
https://www.readbyqxmd.com/read/28551366/modeling-spatial-invasion-of-ebola-in-west-africa
#16
Jeremy P D'Silva, Marisa C Eisenberg
The 2014-2015 Ebola Virus Disease (EVD) epidemic in West Africa was the largest ever recorded, representing a fundamental shift in Ebola epidemiology with unprecedented spatiotemporal complexity. To understand the spatiotemporal dynamics of EVD in West Africa, we developed spatial transmission models using a gravity-model framework at both the national and district-level scales, which we used to compare effectiveness of local interventions (e.g. local quarantine) and long-range interventions (e.g. border-closures)...
May 24, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28538353/fighting-ebola-in-sierra-leone
#17
Erin Kiser
No abstract text is available yet for this article.
June 2017: Nursing
https://www.readbyqxmd.com/read/28530618/robotic-colposacropexy
#18
Miguel Angel Ruiz-León, Lorena Fernández-Montarroso, Natalia Pérez-Romero, Isabel Galante-Romo, Luis Eduardo Resel-Folkersma, Jesús Moreno-Sierra
OBJECTIVES: To review the role of robot- assisted laparoscopic colposacropexy (RALCS) as a treatment for pelvic organ prolapse (POP) accordingly with the available literature and our own experience. METHODS: We have analyzed the studies with the results of robot-assisted colposacropexy (RALCS) and others in which this technique is compared with the abdominal (ACS) and/or the laparoscopic approach (LCS), including our own series. The main data collected are surgical time, blood loss, complications, clinical outcomes, quality of life and the different costs of LCS versus RALCS...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28521722/prevalence-and-risk-factors-for-human-immunodeficiency-virus-hiv-and-syphilis-infections-among-military-personnel-in-sierra-leone
#19
Djeneba Audrey Djibo, Foday Sahr, J Allen McCutchan, Sonia Jain, Maria Rosario G Araneta, Stephanie K Brodine, Richard A Shaffer
CONTEXT: HIV and syphilis infections are common in military personnel in sub-Saharan Africa, which impact combat preparedness and increase demands on the military health care system. The prevalence of HIV is estimated at 1.5% among the general population (15-49 years of age) of Sierra Leone, and the estimated syphilis prevalence ranged from 1.5% to 5.2% based on regional studies. We examined the prevalence and risk factors for these two common sexually transmitted infections in the Sierra Leone military personnel...
May 16, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28518027/measles-cases-during-ebola-outbreak-west-africa-2013-2106
#20
Francesca Colavita, Mirella Biava, Concetta Castilletti, Serena Quartu, Francesco Vairo, Claudia Caglioti, Chiara Agrati, Eleonora Lalle, Licia Bordi, Simone Lanini, Michela Delli Guanti, Rossella Miccio, Giuseppe Ippolito, Maria R Capobianchi, Antonino Di Caro
The recent Ebola outbreak in West Africa caused breakdowns in public health systems, which might have caused outbreaks of vaccine-preventable diseases. We tested 80 patients admitted to an Ebola treatment center in Freetown, Sierra Leone, for measles. These patients were negative for Ebola virus. Measles virus IgM was detected in 13 (16%) of the patients.
June 2017: Emerging Infectious Diseases
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