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https://www.readbyqxmd.com/read/28632205/speckle-modulating-optical-coherence-tomography-in-living-mice-and-humans
#1
Orly Liba, Matthew D Lew, Elliott D SoRelle, Rebecca Dutta, Debasish Sen, Darius M Moshfeghi, Steven Chu, Adam de la Zerda
Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle noise), which imposes significant limitations on its diagnostic capabilities. Here we show speckle-modulating OCT (SM-OCT), a method based purely on light manipulation that virtually eliminates speckle noise originating from a sample. SM-OCT accomplishes this by creating and averaging an unlimited number of scans with uncorrelated speckle patterns without compromising spatial resolution...
June 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28628674/hepatic-microvascular-dysfunction-and-increased-advanced-glycation-end-products-are-components-of-non-alcoholic-fatty-liver-disease
#2
Evelyn Nunes Goulart da Silva Pereira, Raquel Rangel Silvares, Edgar Eduardo Ilaquita Flores, Karine Lino Rodrigues, Isalira Peroba Ramos, Igor José da Silva, Marcelo Pelajo Machado, Rosiane Aparecida Miranda, Carmen Cabanelas Pazos-Moura, Cassiano F Gonçalves-de-Albuquerque, Hugo Caire de Castro Faria-Neto, Eduardo Tibiriça, Anissa Daliry
BACKGROUND: This study aimed to investigate the pathophysiology of hepatic microcirculatory dysfunction in non-alcoholic fatty liver disease (NAFLD). METHODS: In Wistar rats, NAFLD model was induced by 20 weeks of high-fat diet (HFD) feeding. Rolling and adhesion of leukocytes and tissue perfusion in hepatic microcirculation were examined using in vivo microscopic and laser speckle contrast imaging (LSCI), respectively. Oxidative stress and inflamatory parameters were analysed by TBARs, catalase enzyme activity, RT-PCR and ELISA...
2017: PloS One
https://www.readbyqxmd.com/read/28627330/gpu-accelerated-kernel-regression-reconstruction-for-freehand-3d-ultrasound-imaging
#3
Tiexiang Wen, Ling Li, Qingsong Zhu, Wenjian Qin, Jia Gu, Feng Yang, Yaoqin Xie
Volume reconstruction method plays an important role in improving reconstructed volumetric image quality for freehand three-dimensional (3D) ultrasound imaging. By utilizing the capability of programmable graphics processing unit (GPU), we can achieve a real-time incremental volume reconstruction at a speed of 25-50 frames per second (fps). After incremental reconstruction and visualization, hole-filling is performed on GPU to fill remaining empty voxels. However, traditional pixel nearest neighbor-based hole-filling fails to reconstruct volume with high image quality...
July 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/28620822/digital-imaging-information-technology-for-biospeckle-activity-assessment-relative-to-bacteria-and-parasites
#4
Evelio E Ramírez-Miquet, Humberto Cabrera, Hilda C Grassi, Efrén de J Andrades, Isabel Otero, Dania Rodríguez, Juan G Darias
This paper reports on the biospeckle processing of biological activity using a visualization scheme based upon the digital imaging information technology. Activity relative to bacterial growth in agar plates and to parasites affected by a drug is monitored via the speckle patterns generated by a coherent source incident on the microorganisms. We present experimental results to demonstrate the potential application of this methodology for following the activity in time. The digital imaging information technology is an alternative visualization enabling the study of speckle dynamics, which is correlated to the activity of bacteria and parasites...
June 15, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28619445/effects-of-kallidinogenase-on-retinal-edema-and-size-of-non-perfused-areas-in-mice-with-retinal-vein-occlusion
#5
Anri Nishinaka, Shinichiro Fuma, Yuki Inoue, Masamitsu Shimazawa, Hideaki Hara
Kallidinogenase has been used to treat retinal vein occlusion (RVO) in patients, although there are no evidences on the effects of kallidinogenase on the retinal edema and the non-perfused areas in eyes with a RVO. We have established a murine RVO model with retinal edema and non-perfused areas. The purpose of this study was to evaluate the effects of kallidinogenase on the retinal edema and size of the non-perfused areas in the mouse RVO model. We evaluated the thickness of the retinal layers and size of the non-perfused areas, and the blood flow by laser speckle flowgraphy in RVO model...
May 27, 2017: Journal of Pharmacological Sciences
https://www.readbyqxmd.com/read/28616561/left-atrial-appendage-function-assessment-and-thrombus-identification
#6
Jacek Kurzawski, Agnieszka Janion-Sadowska, Marcin Sadowski
BACKGROUND: The diagnosis of thrombus in the left atrium in patients with persistent atrial fibrillation (AF) and may be inconsistent because of variability in thrombus morphology. In some cases it is challenging and requires unusual approach. New Doppler-derived methods might be helpful to identify such thrombi. We evaluated quantitative differences in mechanical function of the left atrial appendage (LAA) basal segments using tissue Doppler imaging (TDI)and speckle tracking echocardiography (STE) in patients with non-valvular AF with and without LAA thrombus and compared them with SR patients...
March 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616546/late-gadolinium-enhancement-does-occur-in-tako-tsubo-cardiomyopathy-a-quantitative-cardiac-magnetic-resonance-and-speckle-tracking-strain-study
#7
Niranjan Gaikwad, Thomas Butler, Ryan Maxwell, Elizabeth Shaw, Wendy E Strugnell, Jonathan Chan, Gemma A Figtree, Richard E Slaughter, Christian Hamilton-Craig
BACKGROUND: Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) has been recommended to distinguish Tako-tsubo cardiomyopathy (TTC) from either acute myocardial infarction or myocarditis. METHOD: 44 consecutive patients with confirmed Mayo Clinic criteria for TTC underwent CMR imaging at 1.5 Tesla during the acute phase. 10 patients who had CMRI to exclude scar related ventricular tachycardia, and had negative studies, were used as negative controls...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616541/accuracy-of-quantitative-echocardiographic-measures-of-right-ventricular-function-as-compared-to-cardiovascular-magnetic-resonance
#8
Christian R Hamilton-Craig, Kathy Stedman, Ryan Maxwell, Bonita Anderson, Tony Stanton, Jonathan Chan, Akira Yamada, Gregory M Scalia, Darryl J Burstow
BACKGROUND: Many echocardiographic parameters have been proposed to evaluate right ventricular (RV) systolic function. We comprehensively assessed a wide range of quantitative echocardiographic parameters in a single cohort compared with same-day cardiovascular magnetic resonance (CMR). METHODS AND RESULTS: 92 subjects were examined prospectively: Group 1 consisted of 46 healthy controls (21 males, 33.4 ± 11.4 years), Group 2 consisted of 46 patients (20 males, 38...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28615148/echocardiographic-assessments-of%C3%A2-longitudinal-left-ventricular-function-in%C3%A2-healthy-english-springer-spaniels
#9
D Dickson, R Shave, M Rishniw, M Patteson
OBJECTIVES: To establish reference intervals for echocardiographic measures of longitudinal left ventricular function in adult English Springer spaniel (ESS) dogs. ANIMALS: This study involved 42 healthy adult ESS. METHODS: Animals were prospectively recruited from a general practice population in the United Kingdom. Dogs were examined twice, at least 12 months apart, to exclude dogs with progressive cardiac disease. Mitral annular plane systolic excursion, tissue Doppler imaging mitral annular velocities and two-dimensional speckle-tracking echocardiographic left ventricular longitudinal strain and strain rate were measured...
June 11, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28614336/ergodic-and-non-ergodic-regimes-in-temporal-laser-speckle-imaging
#10
Pavel Zakharov
The non-ergodicity problem of temporal averaging in the laser speckle contrast imaging (LSCI) is discussed both theoretically and numerically. We demonstrate that temporal speckle statistics assessed within a finite time window might differ from the statistics of the speckle ensemble. The dependence of temporal speckle contrast on sample dynamics is non-monotonic and demonstrates regimes of negative (ergodic), as well as positive correlations with dynamics (non-ergodic). The ergodic regime is similar to an ensemble (spatial) averaging case and is typically assumed for interpretation of LSCI measurements...
June 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28613418/differences-in-optic-nerve-head-microcirculation-between-evening-and-morning-in-patients-with-coronary-artery-disease
#11
Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Yuichi Hori
PURPOSE: To determine whether differences or variation of blood flow in the optic nerve head (ONH) are independent risk factors for coronary artery disease (CAD). METHODS: We studied 144 consecutive patients whose ocular blood flow in the ONH was measured in the evening and morning by laser speckle flowgraphy (LSFG). We analysed the mean blur rate (MBR) throughout the ONH (MBR-A) and in the tissue (MBR-T) and vessels (MBR-V) in the ONH. We also evaluated the MBR-T, -V and -A values obtained in the evening and morning and the variation (Δ) between evening and morning values in each group...
June 14, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/28613174/mulog-or-how-to-apply-gaussian-denoisers-to-multi-channel-sar-speckle-reduction
#12
Charles-Alban Deledalle, Loic Denis, Sonia Tabti, Florence Tupin
Speckle reduction is a longstanding topic in synthetic aperture radar (SAR) imaging. Since most current and planned SAR imaging satellites operate in polarimetric, interferometric or tomographic modes, SAR images are multi-channel and speckle reduction techniques must jointly process all channels to recover polarimetric and interferometric information. The distinctive nature of SAR signal (complex-valued, corrupted by multiplicative fluctuations) calls for the development of specialized methods for speckle reduction...
June 8, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28610912/characteristics-of-cardiomyopathy-in-alstr%C3%A3-m-syndrome-prospective-single-center-data-on-38-patients
#13
Alessandra Brofferio, Vandana Sachdev, Hwaida Hannoush, Jan D Marshall, Jürgen K Naggert, Stanislav Sidenko, Anna Noreuil, Arlene Sirajuddin, Joy Bryant, Joan C Han, Andrew E Arai, William A Gahl, Meral Gunay-Aygun
BACKGROUND: Alström syndrome (AS) is a rare monogenetic disorder with multi-organ involvement. Complex metabolic disturbances are common and cardiomyopathy is a well-recognized feature in infants as well as in older children and adults. Although the mechanism of cardiomyopathy is not known, previous reports suggest that individuals with infantile-onset cardiac disease recover completely. METHODS: In this single center prospective series of 38 children and adults (age range 1...
May 30, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28610239/taxonomic-revision-of-the-speckled-crabs-genus-i-arenaeus-i-dana-1851-brachyura-portunidae-based-on-morphological-and-molecular-data
#14
Lucas L Zupolini, Tatiana Magalhães, Leonardo G Pileggi, Fernando L Mantelatto
The family Portunidae Rafinesque, 1815 presents a series of taxonomic problems such as paraphyletic groups, synonymizations, and unresolved complexes of cryptic species. Arenaeus Dana, 1851, encompasses only two species with mirrored distributions along the coasts of the Americas. Despite of comprising two widespread species, there is a scarcity of information on their biology and ecology and on the relationships with other genera in the family. Because of the lack of studies comprising both species and the imprecise or erroneous taxonomic descriptions for the species of Arenaeus, we conducted a thorough taxonomic revision of the genus and used data from fragments of the 16S rRNA and the cytochrome oxidase I (COI) genes to investigate the validity of Arenaeus cribrarius (Lamarck, 1818) and Arenaeus mexicanus                 (Gerstaecker, 1856)...
June 6, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610038/morphological-and-genetic-evolution-in-eastern-populations-of-the-i-macrhybopsis-i-i-aestivalis-i-complex-cypriniformes-cyprinidae-with-the-descriptions-of-four-new-species
#15
Carter R Gilbert, Richard L Mayden, Steven L Powers
For many years the North American cyprinid fish Macrhybopsis aestivalis (common name: Speckled Chub) was regarded as a single widespread and morphologically variable species, occurring in rivers throughout much of the Mississippi Valley and geographically adjacent eastern Gulf slope drainages, west to the Rio Grande basin in Texas, New Mexico, and Mexico. Eisenhour (1997) completed a morphological study of western populations of the Speckled Chub, the results of which appeared thereafter in published form (Eisenhour 1999, 2004)...
March 30, 2017: Zootaxa
https://www.readbyqxmd.com/read/28608400/myocardial-strain-assessment-using-velocity-vector-imaging-in-normally-grown-fetuses-at-term
#16
Amal A Alsolai, Larissa N Bligh, Ristan M Greer, Alexander Gooi, Sailesh Kumar
OBJECTIVES: The aim was to prospectively assess fetal myocardial deformation at term in normally grown fetuses, using Velocity Vector Imaging (VVI) 2D speckle-tracking technique and explore myocardial deformation changes over the last four weeks of pregnancy. METHODS: This was a prospective, observational, cohort study, at the Mater Mother's Hospital, Brisbane, Australia. A cohort of 276 women with uncomplicated singleton pregnancies underwent fortnightly ultrasound from 36 weeks until delivery...
June 13, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28607564/subclinical-left-ventricular-systolic-dysfunction-in-patients-with-metabolic-syndrome-a-case-control-study-using-two-dimensional-speckle-tracking-echocardiography
#17
Alireza Moaref, Majid Faraji, Maryam Tahamtan
BACKGROUND: The dramatic increase in the prevalence of metabolic syndrome is associated with more increased cardiovascular morbidity and mortality in this group. Some recent studies suggested that metabolic syndrome is associated with increased risk of subclinical left ventricular (LV) systolic dysfunction. In the present cross-sectional case-control study, the utility of two-dimensional speckle tracking echocardiography (STE) was examined to detect early LV systolic dysfunction in this population...
November 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28604934/use-of-kurtosis-for-locating-deep-blood-vessels-in-raw-speckle-imaging-using-a-homogeneity-representation
#18
Hayde Peregrina-Barreto, Elizabeth Perez-Corona, Jose Rangel-Magdaleno, Ruben Ramos-Garcia, Roger Chiu, Julio C Ramirez-San-Juan
No abstract text is available yet for this article.
June 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28602206/strain-rate-in-children-and-young-piglets-mirrors-changes-in-contractility-and-demonstrates-a-force-frequency-relationship
#19
Silvia V Alvarez, Etienne Fortin-Pellerin, Mohammed Alhabdan, Jesus S Lomelin, Michal Kantoch, Joseph Atallah, Lisa K Hornberger, James Y Coe, Po-Yin Cheung, Edythe B Tham, Kandice Mah, Lily Lin, Lindsay Mills, Nee S Khoo
BACKGROUND: In adult humans and pig models, strain rate (SR) correlates strongly with invasive measures of contractility but does not demonstrate a force-frequency relationship, which is a fundamental behavior of myocardial contraction. Given the considerable maturational changes of the myocardium from fetal stages to adulthood, extrapolation of adult findings to the young heart may not be appropriate. We sought to evaluate the SR response of the immature heart to increased heart rate (HR) and inotropic stimulation...
June 8, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28600827/differences-between-time-domain-and-fourier-domain-optical-coherence-tomography-in-imaging-tissues
#20
W Gao, X Wu
It has been numerously demonstrated that both time domain and Fourier domain optical coherence tomography (OCT) can generate high-resolution depth-resolved images of living tissues and cells. In this work, we compare the common points and differences between two methods when the continuous and random properties of live tissue are taken into account. It is found that when relationships that exist between the scattered light and tissue structures are taken into account, spectral interference measurements in Fourier domain OCT (FDOCT) is more advantageous than interference fringe envelope measurements in time domain OCT (TDOCT) in the cases where continuous property of tissue is taken into account...
June 9, 2017: Journal of Microscopy
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