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Aging and diet

Didem Dagdeviren, Zana Kalajzic, Douglas J Adams, Ivo Kalajzic, Alan Lurie, Maija I Mednieks, Arthur R Hand
OBJECTIVE: To determine if spaceflight and microgravity affect non-weight bearing bones and development and mineralization of teeth, reasoning that combining an organ and a cellular level approach can lead to greater insights about these effects. DESIGN: Mandibles and incisors of mice flown on the US STS-135 space shuttle mission and the Russian Bion-M1 satellite were studied using micro-computed tomography and immunohistochemistry. Ground controls were mice housed in standard vivarium cages and flight habitats...
June 7, 2018: Archives of Oral Biology
Gabriela Arandia, Daniela Sotres-Alvarez, Anna Maria Siega-Riz, Elva M Arredondo, Mercedes R Carnethon, Alan M Delamater, Linda C Gallo, Carmen R Isasi, Ashley N Marchante, David Pritchard, Linda Van Horn, Krista M Perreira
BACKGROUND: Acculturation among Hispanic/Latinos has been linked to deteriorating dietary quality that may contribute to obesity risks. This study examined the relationship between acculturation, ethnic identity, and dietary quality in U.S. Hispanic/Latino youth. METHODS: This cross-sectional study included 1298 Hispanic/Latino youth ages 8-16 from the Hispanic Community Health Study/Study of Latino Youth (HCHS/SOL Youth), an ancillary study of offspring of participants in the adult HCHS/SOL cohort...
June 18, 2018: Appetite
Brad J Schoenfeld, Brett S Nickerson, Colin D Wilborn, Stacie L Urbina, Sara B Hayward, James Krieger, Alan A Aragon, Grant M Tinsley
Schoenfeld, BJ, Nickerson, BS, Wilborn, CD, Urbina, SL, Hayward, SB, Krieger, J, Aragon, AA, and Tinsley, G. Comparison of multifrequency bioelectrical impedance vs. dual-energy x-ray absorptiometry for assessing body composition changes after participation in a 10-week resistance training program. J Strength Cond Res XX(X): 000-000, 2018-The purpose of this study was to assess the ability of multifrequency bioelectrical impedance analysis (MF-BIA) to determine alterations in total and segmental body composition across a 10-week resistance training (RT) program in comparison with the criterion reference dual-energy X-ray absorptiometry (DXA)...
June 20, 2018: Journal of Strength and Conditioning Research
Naoko A Chapman, Robert J Jacobs, Andrea J Braakhuis
A systematic literature review was conducted to evaluate the role of diet and food intake in age-related macular degeneration (AMD). Eighteen high-quality studies were identified. Adherence to a Mediterranean diet had decreased risk of AMD progression. An Oriental diet pattern had decreased association with AMD prevalence, whereas a Western diet pattern had increased association with AMD prevalence. High consumption of vegetables rich in carotenoids, and fatty fish containing omega-3 fatty acids was beneficial for those at risk of AMD...
June 21, 2018: Clinical & Experimental Ophthalmology
L S Donnelly, R L Shaw, M Pegington, C J Armitage, D G Evans, A Howell, M N Harvie
BACKGROUND: Weight-loss programmes requiring intermittent energy restriction offer an alternative to continuous energy restriction programmes that typically have low adherence. We reported greater weight loss, better adherence and spontaneous reduced energy intake on healthy eating days with intermittent as opposed to continuous energy restriction. The present study aims to explore why intermittent energy restriction diets exert these positive effects. METHODS: Semi-structured interviews were carried out with 13 women aged 39-62 years, who followed a 4-month intermittent energy restriction (2 days of low energy/low carbohydrate, 5 days of healthy eating)...
June 21, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
Hong-Fang Yang, Xiao-Jing Lin, Xiao-Hui Wang
OBJECTIVE: To investigate the effects of 4-week moderate aerobic exercise plus diet control on serum levels of total insulin-like growth factor 1(IGF-1) and IGF-1 binding protein-3 (IGFBP-3) as well as IGF-1 activity (reflected by molar ratio of IGF-1/IGFBP-3) in female obese adolescents and youths, and their possible role on fat loss, and improvement of glucose and lipid metabolism. METHODS: Nine female obese youths (age:18~19 y) and 30 female obese adolescents (age:14~16 y) were recruited and undertook 4-week aerobic exercise such as swimming and jogging (6 days/week, twice a day, 2 h/time with 5 min rest per 30 min exercise) with gradual increase of intensity from low (heart rate immediately post-exercise of 1st week:100~120 beats/min) to moderate (heart rate immediately post-exercise of 2nd -4th weeks:120~140 beats/min) level, combined with a diet intervention (total daily energy intake of 1 400 or 1 600 kcal according to basal metabolism rate) in Shanghai Dianfeng weight loss enclosed camp...
January 8, 2018: Chinese Journal of Applied Physiology
Fabián Campos, Johanna Abrigo, Francisco Aguirre, Bruno Garcés, Marco Arrese, Saul Karpen, Daniel Cabrera, Marcelo E Andía, Felipe Simon, Claudio Cabello-Verrugio
Sarcopenia is the loss of muscle mass and strength produced by aging or secondary to chronic diseases such as chronic liver disease (CLD). Although not all types of sarcopenia involve the same features, the most common are decreased fiber diameter and myosin heavy chain (MHC) levels, increased activity of ubiquitin-proteasome system (UPS) and reactive oxygen species (ROS). In this study, we aim to characterize the development of sarcopenia secondary to CLD induced by the hepatotoxin 5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)...
June 20, 2018: Pflügers Archiv: European Journal of Physiology
Bo Zhang, Feng Xu, Pingping Hu, Mingyuan Zhang, Kehui Tong, Gang Ma, Yuemei Xu, Liang Zhu, Jiande D Z Chen
BACKGROUND: Functional gastrointestinal disturbance occurs after abdominal surgeries and could last for an extended period of time in some cases. This study was designed (1) to evaluate the effects of needleless transcutaneous electrical acustimulation (TEA) on postoperative recovery, and (2) to investigate the mechanisms involving autonomic function in postoperative patients after removal of gastrointestinal cancers. METHODS: Forty-two patients (33 male, age: 69...
June 21, 2018: American Journal of Gastroenterology
Ahlke Heydemann
The interactions between nutrition and metabolism and skeletal muscle have long been known. Muscle is the major metabolic organ—it consumes more calories than other organs—and therefore, there is a clear need to discuss these interactions and provide some direction for future research areas regarding muscle pathologies. In addition, new experiments and manuscripts continually reveal additional highly intricate, reciprocal interactions between metabolism and muscle. These reciprocal interactions include exercise, age, sex, diet, and pathologies including atrophy, hypoxia, obesity, diabetes, and muscle myopathies...
June 20, 2018: Nutrients
S Pamela K Shiao, James Grayson, Amanda Lie, Chong Ho Yu
To personalize nutrition, the purpose of this study was to examine five key genes in the folate metabolism pathway, and dietary parameters and related interactive parameters as predictors of colorectal cancer (CRC) by measuring the healthy eating index (HEI) in multiethnic families. The five genes included methylenetetrahydrofolate reductase ( MTHFR ) 677 and 1298, methionine synthase ( MTR ) 2756, methionine synthase reductase ( MTRR 66), and dihydrofolate reductase ( DHFR ) 19bp , and they were used to compute a total gene mutation score...
June 20, 2018: Nutrients
Hua Jiang, Ai Zhao, Wenzhi Zhao, Shengjie Tan, Jian Zhang, Yumei Zhang, Peiyu Wang
BACKGROUND: This study aimed to comprehensively evaluate dietary diversity and its associated factors in Chinese preschoolers and explore whether the daily food consumption of children with different dietary diversity-associated characteristics met recommended dietary amounts. METHODS: A cross-sectional study covering seven cities and two villages was conducted and included 697 preschool children aged 3⁻7 years old. Dietary diversity score (DDS) and DDS 10 were calculated based on 24-h dietary recall...
June 20, 2018: Nutrients
Erin K Crowley, Caitriona M Long-Smith, Amy Murphy, Elaine Patterson, Kiera Murphy, Denise M O'Gorman, Catherine Stanton, Yvonne M Nolan
Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar "Western diet" have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health...
June 20, 2018: Marine Drugs
Meng Zhang, Yi Chu, Joseph Mowery, Brandon Konkel, Susana Galli, Alexander C Theos, Nady Golestaneh
Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to secondary photoreceptor degeneration. Recent studies have associated mitochondrial damage with AMD, and we have observed mitochondrial and autophagic dysfunction and repressed peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α in native RPE from AMD donor eyes and their respective induced pluripotent stem cell-derived RPE (AMD RPE-iPSC-RPE)...
June 20, 2018: Disease Models & Mechanisms
J M Gómez-Martin, J A Balsa, E Aracil, M Cuadrado-Ayuso, M Rosillo, G De la Peña, M A Lasunción, H F Escobar-Morreale, J I Botella-Carretero
BACKGROUND: The beneficial effects in lipid profiles after obesity surgery might be associated with the decrease in cardiovascular risk. However, direct comparison between different surgical techniques has not been extensively performed. METHODS: In the present study we compare 20 obese women submitted to laparoscopic Roux en Y gastric bypass (RYGB) with 20 women submitted to sleeve gastrectomy (SG). Twenty control women matched for age and baseline cardiovascular risk were also included...
June 20, 2018: Lipids in Health and Disease
Gilbert C Gee, A B de Castro, Catherine M Crespi, May C Wang, Karen Llave, Eleanor Brindle, Nanette R Lee, Maria Midea M Kabamalan, Anna K Hing
BACKGROUND: Immigrants to the United States are usually healthier than their U.S.-born counterparts, yet the health of immigrants declines with duration of stay in the U.S. This pattern is often seen for numerous health problems such as obesity, and is usually attributed to acculturation (the adoption of "American" behaviors and norms). However, an alternative explanation is secular trends, given that rates of obesity have been rising globally. Few studies of immigrants are designed to distinguish the effects of acculturation versus secular trends, in part because most studies of immigrants are cross-sectional, lack baseline data prior to migration, and do not have a comparison group of non-migrants in the country of origin...
June 20, 2018: BMC Public Health
Kathryn N Porter Starr, Shelley R McDonald, Aubrey Jarman, Melissa Orenduff, Richard Sloane, Carl F Pieper, Connie W Bales
Increases in rates of obesity in the older population are hastening the development of chronic illnesses, including chronic kidney disease (CKD). However, obesity reduction in older adults is besought with concerns about the long-term benefit/risk, especially regarding loss of muscle mass and its impact on function. Higher protein intakes have been advocated to help offset the tendency for loss of muscle during weight reduction but this raises concerns about possible negative effects on older kidneys. We assessed markers of renal function in venous blood samples collected during a six-month randomized controlled weight loss trial of higher protein intake in obese (n = 67; BMI ≥ 30 kg/m2 ) older (≥60 years) adults with physical frailty and age-normal renal status (glomerular filtration rate [GFR] ≥ 45); the Control diet (0...
June 20, 2018: Journal of Nutrition in Gerontology and Geriatrics
Xiao Zhang, Yunhui Gong, Peng Jia, Jieyi Zhang, Hongmei Xue, Liming Quan, Guo Tian, Jingyuan Xiong, Lishi Zhang, Yu Wang, Lin Zhang, Guo Cheng
Background: Little is known about the relationships between diet cost, dietary intake and obesity in Chinese populations. This study explored how diet cost was related to diet quality and obesity among school-aged children in Southwest China. Methods: Data from a cross-sectional study was analysed. Diet cost was estimated based on dietary intake assessed with 24-h dietary recalls and retail food prices. Diet quality was measured using the Chinese Children Dietary Index...
June 18, 2018: Journal of Public Health
Felipe Azevedo Ribeiro, Katherine Ivette Domenech-Pérez, Carmen Josefina Contreras-Castillo, Emery Karoline Wilkerson, Hope Reneé Voegele, Kellen Ballard Hart, Nicolas Jens Herrera, Chris Richard Calkins
The effects of feeding different dietary fat sources with modified distillers grains plus solubles (MDGS) on beef display life were evaluated. Steers (n = 256) were fed for 134 d on either a corn, 40% full-fat MDGS, 40% de-oiled MDGS, or 38% de-oiled MDGS plus 2% corn oil diet. Twenty-four United States Department of Agriculture Choice carcasses (3 head/pen) were randomly selected within each dietary treatment and strip loins were collected and aged for 2, 9, 16, or 23 d. Steaks from each aging period were placed under retail display (RD) conditions for 0, 4, and 7 d...
June 19, 2018: Journal of Animal Science
Alisson Diego Machado, Fernanda Silva Nogueira Dos Anjos, Maria Alice Muniz Domingos, Maria Del Carmen Bisi Molina, Dirce Maria Lobo Marchioni, Isabela Judith Martins Benseñor, Silvia Maria de Oliveira Titan
BACKGROUND: Despite evidence that diet is very important in relation to chronic kidney disease (CKD) progression, studies in this field are scarce and have focused only on some specific nutrients. We evaluated the energy, macronutrient and micronutrient intakes and dietary patterns of non-dialysis CKD participants in the PROGREDIR study. DESIGN AND SETTING: Cross-sectional study; CKD cohort, São Paulo, Brazil. METHODS: Baseline data on 454 participants in the PROGREDIR study were analyzed...
June 18, 2018: São Paulo Medical Journal, Revista Paulista de Medicina
Thomas V Chacko, Subhashini Ganesan
Compared to adults, assessment of dietary intake of school children has always been a great challenge in public health practice. Hence, this paper aims to share our experience in overcoming the problems in dietary assessment of large number of school children aged 6-17 years and the practicality of the tool for quickly identifying the broad gaps in the diet of individual Children for providing them dietary counseling. Based on the Indian Council of Medical Research/National Institute of Nutrition recommendations for balanced diet among school children, a simplified dietary gap assessment tool was developed to identify gross gaps in their diet and also a system of scoring it so as to measure effectiveness of the nutritional educational program...
April 2018: Indian Journal of Public Health
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