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tinnitus types

Masafumi Kobayashi, Maiko Miyagawa, Shin-Ya Nishio, Hideaki Moteki, Taro Fujikawa, Kenji Ohyama, Hirofumi Sakaguchi, Ikuyo Miyanohara, Akiko Sugaya, Yasushi Naito, Shin-Ya Morita, Yukihiko Kanda, Masahiro Takahashi, Kotaro Ishikawa, Yuki Nagano, Tetsuya Tono, Chie Oshikawa, Chiharu Kihara, Haruo Takahashi, Yoshihiro Noguchi, Shin-Ichi Usami
A heterozygous mutation in the Wolfram syndrome type 1 gene (WFS1) causes autosomal dominant nonsyndromic hereditary hearing loss, DFNA6/14/38, or Wolfram-like syndrome. To date, more than 40 different mutations have been reported to be responsible for DFNA6/14/38. In the present study, WFS1 variants were screened in a large series of Japanese hearing loss (HL) patients to clarify the prevalence and clinical characteristics of DFNA6/14/38 and Wolfram-like syndrome. Massively parallel DNA sequencing of 68 target genes was performed in 2,549 unrelated Japanese HL patients to identify genomic variations responsible for HL...
2018: PloS One
Jasper V Smit, Bart J Pielkenrood, Remo A G J Arts, Miranda L Janssen, Yasin Temel, Robert J Stokroos
Purpose: The field of neuromodulation is currently seeking to treat a wide range of disorders with various types of invasive devices. In recent years, several preclinical trials and case reports in humans have been published on their potential for chronic tinnitus. However, studies to obtain insight into patients' willingness to undergo these treatments are scarce. The aim of this survey study was to find out whether tinnitus patients are willing to undergo invasive neuromodulation when taking its risks, costs, and potential benefits into account...
March 5, 2018: American Journal of Audiology
Pedro Helo Dos Santos Neto, Johnni Oswaldo Zamponi, Rogério Hamerschmidt, Gislaine Richter Minhoto Wiemes, Marcio S Rassi, Luis A B Borba
Hearing loss is the most common symptom of vestibular schwannomas (VSs). The management of these lesions includes observation, radiosurgery, and microsurgical resection. Hearing preservation and rehabilitation are the major challenges after the tumor treatment. A 43-year-old man with previous left-sided profound hearing loss and tinnitus presented with a 2-mm left-sided intracanalicular VS. The decision was made to perform a simultaneous cochlear implantation (CI) and microsurgical resection of the tumor. The patient did well postoperatively, with significant improvement of tinnitus, sound localization, and speech recognition in noise...
March 2018: Neurosurgical Focus
Vishakha W Rawool, Chelsea Campbell
OBJECTIVE: This investigation was designed to determine the effectiveness of earmuffs worn by a single individual during shooting practice. DESIGN: Single subject experimental design. STUDY SAMPLE: A 21-year old female recreational shooter, who practiced shooting on a regular basis while using earmuffs participated in the study. She reported occasional noise exposures of other types including car races and demolition derbies but no hearing difficulties or symptoms such as tinnitus...
February 28, 2018: International Journal of Audiology
Hong-Qun Wang, Li Jie, Huai-Yin Shi
BACKGROUND: Low-grade malignant endolymphatic sac tumor (ELST) is a rare neoplasm, occurring in the inner ear and invading the temporal bone. This study aims to investigate the clinicopathological features of low-grade malignant ELSTs. METHODS: The clinicopathological data of 21 patients with low-grade malignant ELSTs were collected and analyzed. RESULTS: The patients were aged 16-71 years, with an average age of 40.3 years and a median age of 39 years, and the male to female ratio was 1:1...
December 14, 2017: Pathology, Research and Practice
Siamak Sabour
Purpose: The purpose of this letter, in response to Hall, Mehta, and Fackrell (2017), is to provide important knowledge about methodology and statistical issues in assessing the reliability and validity of an audiologist-administered tinnitus loudness matching test and a patient-reported tinnitus loudness rating. Method: The author uses reference textbooks and published articles regarding scientific assessment of the validity and reliability of a clinical test to discuss the statistical test and the methodological approach in assessing validity and reliability in clinical research...
February 20, 2018: American Journal of Audiology
Maryam Emadi, Mohammad Rezaei, Sirvan Najafi, Ali Faramarzi, Farhad Farahani
The aim of this study was to investigate the possible role of cochlear outer hair cell function with TEOAE and DPOAE tests in patients with normal hearing and tinnitus. 25 tinnitus patients with normal hearing sensitivity selected as study group. Control group consist of 50 normal hearing subjects without tinnitus. All subjects had thresholds below 25 dBHL at frequencies 250-8,000 Hz, tympanogram type A and normal acoustic reflex thresholds. TEOAE were recorded with click stimulus at 80 dB SPL at 1,000, 2,000, 3,000 and 4000 Hz...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
Kathleen C M Campbell, Colleen G Le Prell
Ototoxicity diagnosis and management has historically been approached using a variety of methods. However, in recent years a consensus on useful and practical approaches has been developed through clinical guidelines of the American Speech Language Hearing Association, the American Academy of Audiology, and multiple clinical trials published in peer-reviewed literature. Some of the guidelines and approaches are used to detect and monitor ototoxicity, while others are used to grade adverse events. Some of the audiologic measures are primary, while others are adjunct measures and may be tailored to the specific needs of the patient or clinical trial...
February 6, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Mustafa Aslıer, Nesibe Gül Yüksel Aslıer
Objective: The aim of this study is to identify the otologic injuries due to handmade explosive-welded blast travma in the law enforcement officers during the combat operations in the curfew security region and to specify the disorders that Otolaryngology and Head Neck Surgery (OHNS) physicians can face during such operations. Methods: Medical records of patients in law enforcement who were initially treated by OHNS physicians of Silopi State Hospital during combat operations, between December 14, 2015 and January 15, 2016 were reviewed...
June 2017: Turkish Archives of Otorhinolaryngology
Edoardo Covelli, Guido Trasimeni, Chiara Filippi, Valerio Fabiani, Simonetta Monini, Luigi Volpini, Maurizio Barbara
To the best of our knowledge, only 2 cases of a simultaneous contralateral vestibular schwannoma (VS) and middle ear paraganglioma (MEP) have previously been reported in literature. We report the third case observed in a 43-year-old male, who presented with an 11-year history of right-sided hearing loss and a 1-year history of left-sided pulsatile tinnitus. A magnetic resonance imaging (MRI) showed a VS on the right side and computer tomography (CT) identified a Fisch type A1 paraganglioma on the left side...
December 2017: Journal of International Advanced Otology
Jin Li, Yi Zhang, Xinxing Fu, Jingtao Bi, Yanhong Li, Bo Liu, Luo Zhang
BACKGROUND: The association between type 2 diabetes mellitus (T2DM) and hearing loss has not been fully investigated and there is little information on the effects of pre-diabetes on alterations in auditory function in Chinese subjects. METHODS: The study recruited 51 patients with T2DM, 55 patients with pre-diabetes and 43 control subjects. Auditory function was assessed by pure tone audiometry (PTA) tests and distortion product of otoacoustic emissions (DPOAEs)...
January 18, 2018: Acta Oto-laryngologica
Stefania Barozzi, Umberto Ambrosetti, Susanna Løve Callaway, Thomas Behrens, Silvia Passoni, Luca Del Bo
BACKGROUND: In Tinnitus Retraining Therapy (TRT) sound stimulation is conventionally performed with low-level broadband sound generators; since the patient has to receive it for many hours in a day, it is important that the sound is tolerable and agreeable to the patient. A clinical trial was undertaken to evaluate the effect of different colour sound generators on tinnitus. The colour of a sound refers to the power spectrum of the signal. The sound generators used in this study provide the option to choose the preferred or most acceptable sound among white, red and pink noise...
December 1, 2017: International Tinnitus Journal
Sujoy Kumar Makar, Geetha Mukundan, Geeta Gore
OBJECTIVE: To observe cochlear and brainstem function in normal hearing ears with tinnitus using DPOAE and ABR audiometry. DESIGN: Case-control study. SAMPLE SIZE: Included 60 normal hearing male patients with age less than 45 years; control group consisted of 30 patients without tinnitus and the study group consisted of those with unilateral tinnitus of at least 6 month duration. Pure tone audiometry, tinnitus matching (pitch & loudness), DPOAE (SNR & Amplitude) and ABR results of absolute latency of wave I, III and V, with IPL difference of I-III, III-V & I-V, and ILD-V were investigated...
December 1, 2017: International Tinnitus Journal
Ismail Aytac, Elif Baysal, Secaattin Gulsen, Koray Tumuklu, Cengiz Durucu, Lütfi Semih Mumbuc, MUzaffer Kanlikama
OBJECTIVE: Tinnitus is described as the perception of sound without any external acoustic stimulation. Any pathology of auditory pathways or any system of the human body may result with tinnitus. The pathophysiology of tinnitus accompanying the disorders of auditory system is not fully understood and there is not any particular effective treatment method has been specified. Tinnitus masking therapy has been reported as an effective treatment modality in the treatment of tinnitus. In this study, the results of tinnitus masking treatment on the parameters were evaluated prospectively...
December 1, 2017: International Tinnitus Journal
Józef Mierzwiński, Justyna Kosowska, Justyna Tyra, Karolina Haber, Maria Drela, Dariusz Paczkowski, Paweł Burduk
BACKGROUND: Fibrous dysplasia is a slowly progressive benign fibro-osseous disorder that involves one or multiple bones with a unilateral distribution in most cases. It is a lesion of unknown etiology, uncertain pathogenesis, and diverse histopathology. Temporal bone involvement is the least frequently reported type, especially in children. We reviewed available articles regarding fibrous dysplasia with temporal bone involvement in children and added four patients aged 7 to 17 years who were diagnosed and treated in our institution from 2006 to 2017...
January 15, 2018: World Journal of Surgical Oncology
Steffen Rosahl, Christopher Bohr, Michael Lell, Klaus Hamm, Heinrich Iro
Vestibular schwannomas (VS) expand slowly in the internal auditory canal, in the cerebellopontine angle, inside the cochlear and the labyrinth. Larger tumors can displace and compress the brainstem. With an annual incidence of 1:100,000 vestibular schwannoma represent 6-7% of all intracranial tumors. In the cerebellopontine angle they are by far the most neoplasm with 90% of all lesions located in this region. Magnetic resonance imaging (MRI), audiometry, and vestibular diagnostics are the mainstays of the clinical workup for patients harboring tumors...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
Leonardo Renieri, Caterina Michelozzi, Waleed Brinjikji, Jean Darcout, Adrien Guenego, Ivan Vukasinovic, Philippe Tall, Fabrice Bonneville, Anne-Christine Januel, Christophe Cognard
BACKGROUND AND PURPOSE: Type I and IIa dural arteriovenous fistulas (DAVFs) have a low hemorrhagic risk, but are often the cause of debilitating tinnitus that requires treatment. While Onyx® and PHIL™ (Precipitating hydrophobic injectable liquid) transarterial embolization represent the first endovascular option, there are occasional cases where performing angioplasty and stenting of the affected sinus may lead to satisfactory results. MATERIAL AND METHODS: We retrospectively analyzed four consecutive cases of patients with DAVF-induced pulsatile tinnitus secondary to type I and II DAVFs who were treated with angioplasty and stenting of the sinus only...
December 14, 2017: Clinical Neuroradiology
M Singh, M Kaur, B Singh, K Singh, A Singh, A Kaur
OBJECTIVE: The aim of the study was to study the closure of dry central type of tympanic membrane perforations by chemical cautery and improvement of hearing, to analyse the effect of Gelfoam on nonhealing small tympanic membrane perforations, and to examine the relevance of conservative means of closure of tympanic membrane perforations as an office procedure. MATERIALS AND METHODS: In this study, 100 patients attending the outpatient department were enrolled. Cautery of perforation margin was carried out with 50% trichloroacetic acid (TCA)...
October 2017: Nigerian Journal of Clinical Practice
Lindsey Tutaj, Derek J Hoare, Magdalena Sereda
OBJECTIVES: In most cases, tinnitus is accompanied by some degree of hearing loss. Current tinnitus management guidelines recognize the importance of addressing hearing difficulties, with hearing aids being a common option. Sound therapy is the preferred mode of audiological tinnitus management in many countries, including in the United Kingdom. Combination instruments provide a further option for those with an aidable hearing loss, as they combine amplification with a sound generation option...
November 17, 2017: Ear and Hearing
Hanna Sahlsten, Tero Taiminen, Max Karukivi, Noora Sjösten, Johanna Nikkilä, Juuso Virtanen, Janika Paavola, Juho Joutsa, Katri Niinivirta-Joutsa, Mari Takala, Anu Holm, Esa Rauhala, Eliisa Löyttyniemi, Reijo Johansson, Satu K Jääskeläinen
OBJECTIVE: Chronic tinnitus has been associated with several psychiatric disorders. Only few studies have investigated these disorders using validated diagnostic interviews. The aims were to diagnose psychiatric and personality disorders with structured interviews, to assess self-rated psychiatric symptoms and elucidate temporal relations between psychiatric disorders and tinnitus. DESIGN: Current and lifetime DSM-IV diagnoses of axis-I (psychiatric disorders) and axis-II (personality disorders) were assessed using structured clinical interviews (SCID-I and -II)...
November 30, 2017: International Journal of Audiology
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