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tinnitus on industry

James K Trevathan, Ali Yousefi, Hyung Ook Park, John J Bartoletta, Kip A Ludwig, Kendall H Lee, J Luis Lujan
Neurochemical changes evoked by electrical stimulation of the nervous system have been linked to both therapeutic and undesired effects of neuromodulation therapies used to treat obsessive-compulsive disorder, depression, epilepsy, Parkinson's disease, stroke, hypertension, tinnitus, and many other indications. In fact, interest in better understanding the role of neurochemical signaling in neuromodulation therapies has been a focus of recent government- and industry-sponsored programs whose ultimate goal is to usher in an era of personalized medicine by creating neuromodulation therapies that respond to real-time changes in patient status...
February 15, 2017: ACS Chemical Neuroscience
Thomas Winther Frederiksen, Cecilia Høst Ramlau-Hansen, Zara Ann Stokholm, Matias Brødsgaard Grynderup, Åse Marie Hansen, Søren Peter Lund, Jesper Kristiansen, Jesper Medom Vestergaard, Jens Peter Bonde, Henrik Albert Kolstad
PURPOSE: The purpose of this study was to evaluate the influence of occupational noise (current and cumulative doses) and psychosocial work factors (psychological demands and decision latitude) on tinnitus occurrence among workers, using objective and non-self-reported exposure measures to prevent reporting bias. METHODS: In a cross-sectional study, we analyzed data from a Danish survey from 2009 to 2010 that included 534 workers from children day care units and 10 manufacturing trades...
February 2017: International Archives of Occupational and Environmental Health
David V Gauvin, Joshua D Yoder, Rachel L Tapp, Theodore J Baird
Life experiences, industrial/environmental exposures, and administration of Food and Drug Administration (FDA)-approved drugs may have unintended but detrimental effects on peripheral and central auditory pathways. Most relevant to the readership of this journal is the role that drug treatments approved by the FDA as safe and effective appear to interact with 3 independent modes of toxicity within the small compartment of the ear. What may seem to be trivial drug-induced toxicity has the potential to change important measures of quality of life and functional capacity of mid- to late-life patients...
May 18, 2016: International Journal of Toxicology
Dana N Halevi-Katz, Erez Yaakobi, Hanna Putter-Katz
Noise-induced hearing loss (NIHL) has been extensively studied in industrial work environments. With the advent of new technologies, loud music has been increasingly affecting listeners outside of the industrial setting. Most research on the effects of music and hearing loss has focused on classical musicians. The purpose of the current study was to examine the relationship between the amount of experience a professional pop/rock/jazz musician has and objective and subjective variables of the musician's hearing loss...
May 2015: Noise & Health
Deborah A Hall, Haúla Haider, Dimitris Kikidis, Marzena Mielczarek, Birgit Mazurek, Agnieszka J Szczepek, Christopher R Cederroth
In Europe alone, over 70 million people experience tinnitus; for seven million people, it creates a debilitating condition. Despite its enormous socioeconomic relevance, progress in successfully treating the condition is somewhat limited. The European Union has approved funding to create a pan-European tinnitus research collaboration network (2014-2018). The goal of one working group is to establish an international standard for outcome measurements in clinical trials of tinnitus. Importantly, this would enhance tinnitus research by informing sample-size calculations, enabling meta-analyses, and facilitating the identification of tinnitus subtypes, ultimately leading to improved treatments...
2015: Trends in Hearing
Sofie Fredriksson, Oscar Hammar, Kjell Torén, Artur Tenenbaum, Kerstin Persson Waye
OBJECTIVE: There is a lack of research on effects of occupational noise exposure in traditionally female-dominated workplaces. Therefore, the aim of this study was to assess risk of noise-induced hearing-related symptoms among obstetrics personnel. DESIGN: A cross-sectional study was performed at an obstetric ward in Sweden including a questionnaire among all employees and sound level measurements in 61 work shifts at the same ward. PARTICIPANTS: 115 female employees responded to a questionnaire (72% of all 160 employees invited)...
2015: BMJ Open
Oliver C Steinbach
The present industry update covers the period 1 April-30 April 2013, with information sourced from company press releases, regulatory and patent agencies as well as the scientific literature. Next to the publication of a number of industry reports (MarketsandMarkets) on drug-delivery technology, companies and market projections, a number of original manuscripts from the nanotechnology field and its applicability for drug delivery, such as the use of silica-based nanoparticle and self-propelled 'microrockets', were received...
July 2013: Therapeutic Delivery
Berthold Langguth, Ana Belén Elgoyhen
INTRODUCTION: Tinnitus, the phantom perception of sound, is a highly prevalent disorder and treatment is elusive. AREAS COVERED: This review focuses on clinical research regarding pharmacological treatments for tinnitus. The authors searched PubMed databases for English language articles related to pharmacological treatment of tinnitus, published through August 2012. The keywords "tinnitus AND pharmacological treatment" and "tinnitus AND drugs" were used. The search focused on clinical trials, but was complemented by other articles and information from clinical trial registries...
December 2012: Expert Opinion on Pharmacotherapy
John Martin Hempel, Alexander Becker, Joachim Müller, Eike Krause, Alexander Berghaus, Thomas Braun
OBJECTIVE: To obtain clinical and audiometric findings in traumatic tympanic membrane perforations from a typical patient collective in a Western industrial nation because the appropriate data have an important relevance in medicolegal questions. STUDY DESIGN: Retrospective data collection. SETTING: Germany's largest university clinic for otorhinolaryngology, head and neck surgery. SUBJECT AND METHODS: From the medical records of 198 patients with traumatic tympanic membrane perforations, the following data were collected: demographic data, date and mechanism of the trauma, otoscopic findings and collateral injuries, kind of therapy and its results, pure tone audiometry, and statement of tinnitus or vertigo in the course...
October 2012: Otology & Neurotology
Christo Pantev, Hidehiko Okamoto, Henning Teismann
Music has increasingly been used as a tool for investigation of human cognition and its underlying brain mechanisms. However, music can be used also for neurorehabilitation. Chronic tinnitus is a symptom with high prevalence, especially in industrialized countries. There is evidence that the tinnitus perception is related to unfavorable cortical plastic changes. Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus. Because cortical organization can be modified by behavioral training, potentially via reversing maladaptive auditory cortex reorganization, we attempted to reduce tinnitus loudness by exposing chronic tinnitus patients to self-chosen, enjoyable music that was modified ("notched") to contain no energy in the frequency range surrounding the individual tinnitus frequency and thus attracting lateral inhibition to the brain area generating tinnitus...
April 2012: Annals of the New York Academy of Sciences
Emmanuel D Kitcher, Grace Ocansey, Daniel A Tumpi
Noise-induced hearing loss (NIHL) is an irreversible sensorineural hearing loss associated with exposure to high levels of excessive noise. This paper aims to assess the prevalence of early NIHL and the awareness of the effects of noise on health among stone crushing industry workers. This was a comparative cross-sectional study in Ghana of 140 workers from the stone crushing industry compared with a control group of 150 health workers. The stone workers and controls were evaluated using a structured questionnaire, which assessed symptoms of hearing loss, tinnitus, knowledge on the health hazards associated with work in noisy environment and the use of hearing protective device...
March 2012: Noise & Health
Berthold Langguth, Ana Belén Elgoyhen
One in ten adults has clinically significant subjective tinnitus, and for one in hundred, tinnitus severely affects their quality of life. Despite the significant unmet clinical need for a safe and effective drug targeting tinnitus relief, there is currently not a single FDA-approved drug on the market. Even a drug that produces a small but significant effect would have a huge therapeutic impact. In the last few years, there have been significant advances in i) the understanding of the pathophysiology of the different forms of tinnitus, ii) the establishment of valid animal models and iii) the development of clinical trial methodology...
December 2011: Expert Opinion on Emerging Drugs
Kyoo Sang Kim
In this article, current status of noise exposure in workplaces, trend of workers with noise-induced hearing loss (NIHL), and prevalence of NIHL in workers by industry and job category in Korea were reviewed. In addition, trends of research on the audiological effects such as hearing loss from noise and occupational hearing loss from non-noise in Korea were addressed through reports in industrial audiology. Though noise exposure level has improved, noise still shows the highest rate of cases exceeding exposure limit among workplace hazards...
December 2010: Journal of Korean Medical Science
David W Jang, Erika Johnson, Sujana S Chandrasekhar
EDUCATIONAL OBJECTIVE: At the conclusion of this presentation, the participants should be able to identify the principles behind the Neuromonics™ Tinnitus Treatment (NTT) and understand its strengths and potential shortfalls. OBJECTIVES: To describe the preliminary experience and efficacy of the NTT in an independent, non-industry sponsored private otology practice clinical study. STUDY DESIGN: Case series with retrospective chart review and post-intervention quality of life questionnaire...
2010: Laryngoscope
Tsafnat Test, Ayala Canfi, Arnona Eyal, Ilana Shoam-Vardi, Einat K Sheiner
OBJECTIVE: To assess connections between sleeping quality and hearing impairment due to prolonged exposure to industrial noise. DESIGN: Observational cross-sectional study. SETTING: Occupational clinic of the Clalit Health Services in Israel. PARTICIPANTS: 298 male volunteers occupationally exposed to harmful noise, who had an audiometric examination performed by an occupational nurse as a part of the national workers health supervision programs...
January 2011: Sleep
Stephen Tower
MoM hip bearings are being scrutinized due to high early failure rates and concerns that the results of the revision surgeries will be poor. However, orthopedic surgeons and the general medical community are unaware that patients with MoM bearings are also at risk for cobaltism. Medical providers need to know that hip arthroplasty implantees that present with symptom complexes that include tinnitus, deafness, vertigo, visual changes, rashes, hypothyroidism, tremor, dyspnea on exertion, mood disorders, dementia, heart failure, and peripheral neuropathy may be presenting arthroprosthetic cobaltism...
September 2010: Alaska Medicine
Fei Zhao, Vinaya K C Manchaiah, David French, Sharon M Price
It has been generally accepted that excessive exposure to loud music causes various hearing symptoms (e.g. tinnitus) and consequently leads to a risk of permanent hearing damage, known as noise-induced hearing loss (NIHL). Such potential risk of NIHL due to loud music exposure has been widely investigated in musicians and people working in music venues. With advancements in sound technology and rapid developments in the music industry, increasing numbers of people, particularly adolescents and young adults, are exposing themselves to music on a voluntary basis at potentially harmful levels, and over a substantial period of time, which can also cause NIHL...
January 2010: International Journal of Audiology
Jo-Anne M Abbott, Viktor Kaldo, Britt Klein, David Austin, Catherine Hamilton, Leon Piterman, Ben Williams, Gerhard Andersson
The effectiveness of a therapist-supported Internet intervention program for tinnitus distress in an industrial setting was evaluated using a cluster randomised design. Fifty-six Australian employees of two industrial organisations were randomly assigned, based on their work site (18 work sites from BP Australia and five from BHP Billiton), to either a cognitive behavioural therapy (CBT) program or an information-only control program. Participants were assessed at pre- and post-program, measuring tinnitus distress, depression, anxiety, stress, quality of life, and occupational health...
2009: Cognitive Behaviour Therapy
Luciara Giacobe Steinmetz, Bianca Simone Zeigelboim, Adriana Bender M Lacerda, Thaïs Catalani Morata, Jair M Marques
This study evaluated the interference of tinnitus on the quality of life for noise-exposed workers enrolled in a hearing conservation program. Noise measurements, a questionnaire, a Brazilian version of the Tinnitus Handicap Inventory (THI), and pure-tone audiometry were conducted with 52 participants (mean age, 29 years) who suffered from tinnitus. THI results indicated that tinnitus had the greatest influence in the functional scale (54%). Significant correlations (p < .05) were observed between the periodicity of tinnitus and noise exposure level; degree of tinnitus and exposure to chemicals; total THI score and the scores of the catastrophic, emotional, and functional scales; score of the emotional scale and the functional scale; and results of the THI and the general state of health...
2008: International Tinnitus Journal
Kamakshi V Gopal
Millions of people around the world are exposed to industrial organic solvents such as toluene and xylene in the manufacturing sectors. Solvents are neurotoxic substances that are detrimental to the functioning of the nervous system, including the central auditory nervous system (CANS). This study investigated hearing and auditory processing in seven individuals with a history of exposure to industrial solvents. A battery of audiological tests was administered to all subjects: pure tone, speech, and impedance audiometry, otoacoustic emissions tests, auditory brainstem responses, middle latency responses, as well as the SCAN-A and R-SPIN tests with low predictability sentence lists...
July 2008: Noise & Health
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