keyword
MENU ▼
Read by QxMD icon Read
search

muscle architecture

keyword
https://www.readbyqxmd.com/read/29150270/m-biceps-femoris-a-wolf-in-sheep-s-clothing-the-downside-of-a-lower-limb-injury-prevention-training
#1
Thomas Ertelt, Thomas Gronwald
Both, hamstring and ACL injuries are among the most typical injuries, particularly in change of direction and high speed running sports. They're also difficult to treat. Therefore, in the past few years, sports medicine practitioners and exercise scientists have mainly been focusing on the development and implementation of preventive programs in order to reduce the number of lower limb injuries, mainly by improving knee alignment. A number of studies have been able to prove the success of these training interventions, which are mainly addressing sensorimotor abilities and plyometric activities...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29146686/specific-force-of-the-vastus-lateralis-in-adults-with-achondroplasia
#2
David Thomas Sims, Gladys L Onambele-Pearson, Adrian Burden, Carl Payton, Christopher I Morse
Achondroplasia is a clinical condition defined by shorter stature and disproportionate limb length. Force production in able-bodied individuals (controls) is proportional to muscle size, but given the disproportionate nature of Achondroplasia, normalising to anatomical cross sectional area (ACSA) is inappropriate. The aim of this study was to assess specific force of the vastus lateralis (VL) in 10 adults with Achondroplasia (22 ±3 yrs) and 18 gender matched controls (22 ±2 yrs). Isometric torque (iMVCτ) of the dominant knee extensors (KE) and in vivo measures of VL muscle architecture, volume, activation and patella tendon moment arm were used to calculate VL physiological CSA (PCSA), fascicle force and specific force in both groups...
November 16, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29146092/ultrasonographic-evaluation-of-changes-in-the-muscle-architecture-of-the-gastrocnemius-with-botulinum-toxin-treatment-for-lower-extremity-spasticity-in-children-with-cerebral-palsy
#3
Akihiro Kawano, Taiichiro Yanagizono, Ichiro Kadouchi, Tetsuya Umezaki, Etsuo Chosa
BACKGROUND: Botulinum toxin A treatment involves injecting botulinum toxin A to relax muscle spasticity. Using ultrasonography, this study examined changes in the muscle architecture before and after treatment to evaluate the influence of botulinum toxin A injection on muscles. METHODS: The participants included 18 children (mean age, 6.2 years) with cerebral palsy who were treated with botulinum toxin A for lower extremity spasticity and 27 healthy children (mean age, 6...
November 13, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29142168/background-data-on-nod-shi-scid-il-2r%C3%AE-null-mice-nog-mice
#4
Kenichiro Kasahara, Yachiyo Fukunaga, Saori Igura, Rie Andoh, Tsubasa Saito, Isamu Suzuki, Hiroyuki Kanemitsu, Daisuke Suzuki, Ken Goto, Daichi Nakamura, Masahiro Mochizuki, Masahiko Yasuda, Ryo Inoue, Kazutoshi Tamura, Mariko Nagatani
To obtain background data of NOD/Shi-scid IL-2Rγ(null) (NOG) mice, severely immunedeficient mice, a total of 120 animals were examined at 7, 26 and 52 weeks-old (20 mice/sex/group). The survival rate at 52 weeks-old was 95% (19/20) in both sexes. Clinically, circling behavior in one direction along the cage wall was observed in males after 8 weeks and females after 47 weeks-old, and hunchback position was found in males after 32 weeks-old. Hematologically, lymphocyte count markedly decreased at all ages, while white blood cell count increased in several mice at 52 weeks-old...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/29140178/infraspinatus-cross-sectional-area-and-shoulder-range-of-motion-change-following-live-game-baseball-pitching
#5
Brett S Pexa, Eric D Ryan, Elizabeth E Hibberd, Elizabeth Teel, Terri Jo Rucinski, Joseph B Myers
CONTEXT: Following a baseball pitching bout, changes can occur to glenohumeral range of motion that could be linked to injury. These effects are in part due to the posterior shoulder's eccentric muscle activity, which can disrupt muscle contractile elements and lead to changes in muscle cross sectional area (CSA), as measured by ultrasound. OBJECTIVE: To assess changes in muscle CSA, and range of motion immediately before and after pitching, and days 1-5 following pitching...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29139316/association-of-gastrocnemius-muscle-stiffness-with-passive-ankle-joint-stiffness-and-sex-related-difference-in-the-joint-stiffness
#6
Kintaro Chino, Hideyuki Takashi
Passive ankle joint stiffness is affected by all structures located within and over the joint, and is greater in men than in women. Localized muscle stiffness can be assessed by ultrasound shear wave elastography, and muscle architecture such as fascicle length and pennation angle can be measured by B-mode ultrasonography. Thus, we assessed localized muscle stiffness of the medial gastrocnemius (MG) with consideration of individual variability in the muscle architecture, and examined the association of the muscle stiffness with passive ankle joint stiffness and the sex-related difference in the joint stiffness...
November 15, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29116573/an-evidence-based-framework-for-strengthening-exercises-to-prevent-hamstring-injury
#7
REVIEW
Matthew N Bourne, Ryan G Timmins, David A Opar, Tania Pizzari, Joshua D Ruddy, Casey Sims, Morgan D Williams, Anthony J Shield
Strength training is a valuable component of hamstring strain injury prevention programmes; however, in recent years a significant body of work has emerged to suggest that the acute responses and chronic adaptations to training with different exercises are heterogeneous. Unfortunately, these research findings do not appear to have uniformly influenced clinical guidelines for exercise selection in hamstring injury prevention or rehabilitation programmes. The purpose of this review was to provide the practitioner with an evidence-base from which to prescribe strengthening exercises to mitigate the risk of hamstring injury...
November 7, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29112569/stromal-cell-derived-factor-1-plasmid-regenerates-both-smooth-and-skeletal-muscle-after-anal-sphincter-injury-in-the-long-term
#8
Li Sun, Mei Kuang, Marc Penn, Margot S Damaser, Massarat Zutshi
BACKGROUND: Regenerating muscle at a time remote from injury requires re-expression of cytokines to attract stem cells to start and sustain the process of repair. OBJECTIVE: We aimed to evaluate the sustainability of muscle regeneration after treatment with a nonviral plasmid expressing stromal cell-derived factor 1. DESIGN: This was a randomized study. SETTINGS: The study was conducted with animals in a single research facility...
December 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29110545/serum-from-ccl4-induced-acute-rat-injury-model-induces-differentiation-of-adscs-towards-hepatic-cells-and-reduces-liver-fibrosis
#9
Maria Tayyab Baig, Gibran Ali, Sana Javaid Awan, Umara Shehzad, Azra Mehmood, Sadia Mohsin, Shaheen N Khan, Sheikh Riazuddin
Cellular therapies hold promise to alleviate liver diseases. This study explored the potential of allogenic serum isolated from rat with acute CCl4 injury to differentiate adipose derived stem cells (ADSCs) towards hepatic lineage. Acute liver injury was induced by CCl4 which caused significant increase in serum levels of VEGF, SDF1α and EGF. ADSCs were preconditioned with 3% serum isolated from normal and acute liver injury models. ADSCs showed enhanced expression of hepatic markers (AFP, albumin, CK8 and CK19)...
November 7, 2017: Growth Factors
https://www.readbyqxmd.com/read/29098300/-ultrasound-of-muscular-diseases-in-children-and-adolescents
#10
REVIEW
L von Rohden, Julian H W Jürgens
BACKGROUND: The increasing number of treatable hereditary neuromuscular diseases in children requires a diagnostic tool that can quickly, safely, and noninvasively identify affected patients directly after birth or when showing initial clinical symptoms. With clinical analysis alone, this is very difficult. IMAGING MODALITY: Near-field sonography of skeletal muscles has gradually become established as a successful method over the last 35 years. METHODOLOGICAL INNOVATIONS: Examination is performed using a strictly standardized protocol in isotopic muscle regions and with standardized sections and application parameters...
November 2, 2017: Der Radiologe
https://www.readbyqxmd.com/read/29097688/diverse-coordinate-frames-on-sensorimotor-areas-in-visuomotor-transformation
#11
Yusuke Fujiwara, Jongho Lee, Takahiro Ishikawa, Shinji Kakei, Jun Izawa
The visuomotor transformation during a goal-directed movement may involve a coordinate transformation from visual 'extrinsic' to muscle-like 'intrinsic' coordinate frames, which might be processed via a multilayer network architecture composed of neural basis functions. This theory suggests that the postural change during a goal-directed movement task alters activity patterns of the neurons in the intermediate layer of the visuomotor transformation that recieves both visual and proprioceptive inputs, and thus influence the multi-voxel pattern of the blood oxygenation level dependent signal...
November 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29081541/a-continuum-mechanics-based-musculo-mechanical-model-for-esophageal-transport
#12
Wenjun Kou, Boyce E Griffith, John E Pandolfino, Peter J Kahrilas, Neelesh A Patankar
In this work, we extend our previous esophageal transport model using an immersed boundary (IB) method with discrete fiber-based structural model, to one using a continuum mechanics-based model that is approximated based on finite elements (IB-FE). To deal with the leakage of flow when the Lagrangian mesh becomes coarser than the fluid mesh, we employ adaptive interaction quadrature points to deal with Lagrangian-Eulerian interaction equations based on a previous work (Griffith and Luo [1]). In particular, we introduce a new anisotropic adaptive interaction quadrature rule...
October 1, 2017: Journal of Computational Physics
https://www.readbyqxmd.com/read/29074967/a-proteomic-analysis-provides-novel-insights-into-the-stress-responses-of-caenorhabditis-elegans-towards-nematicidal-cry6a-toxin-from-bacillus-thuringiensis
#13
Bing Wang, Haiwen Wang, Jing Xiong, Qiaoni Zhou, Huan Wu, Liqiu Xia, Lin Li, Ziquan Yu
Cry6A represents a novel family of nematicidal crystal proteins from Bacillus thuringiensis. It has distinctive architecture as well as mechanism of action from Cry5B, a highly focused family of nematicidal crystal proteins, and even from other insecticidal crystal proteins containing the conserved three-domain. However, how nematode defends against Cry6A toxin remains obscure. In this study, the global defense pattern of Caenorhabditis elegans against Cry6Aa2 toxin was investigated by proteomic analysis. In response to Cry6Aa2, 12 proteins with significantly altered abundances were observed from worms, participating in innate immune defense, insulin-like receptor (ILR) signaling pathway, energy metabolism, and muscle assembly...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29074566/actomyosin-contractility-regulators-stabilize-the-cytoplasmic-bridge-between-the-two-primordial-germ-cells-during-c-elegans-embryogenesis
#14
Eugénie Goupil, Rana Amini, David H Hall, Jean-Claude Labbé
Stable cytoplasmic bridges arise from failed cytokinesis, the last step of cell division, and are a key feature of syncytial architectures in the germ line of most metazoans. Whereas the C. elegans germ line is syncytial, its formation remains poorly understood. We found that the germline precursor blastomere, P4, fails cytokinesis, leaving a stable cytoplasmic bridge between the two daughter cells, Z2 and Z3 Depletion of several regulators of actomyosin contractility resulted in a regression of the membrane partition between Z2 and Z3, indicating that they are required to stabilize the cytoplasmic bridge...
October 26, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/29069594/columnar-intrinsic-cues-shape-premotor-input-specificity-in-locomotor-circuits
#15
Myungin Baek, Chiara Pivetta, Jeh-Ping Liu, Silvia Arber, Jeremy S Dasen
Control of movement relies on the ability of circuits within the spinal cord to establish connections with specific subtypes of motor neuron (MN). Although the pattern of output from locomotor networks can be influenced by MN position and identity, whether MNs exert an instructive role in shaping synaptic specificity within the spinal cord is unclear. We show that Hox transcription-factor-dependent programs in MNs are essential in establishing the central pattern of connectivity within the ventral spinal cord...
October 24, 2017: Cell Reports
https://www.readbyqxmd.com/read/29058612/skeletal-muscle-mechanics-energetics-and-plasticity
#16
REVIEW
Richard L Lieber, Thomas J Roberts, Silvia S Blemker, Sabrina S M Lee, Walter Herzog
The following papers by Richard Lieber (Skeletal Muscle as an Actuator), Thomas Roberts (Elastic Mechanisms and Muscle Function), Silvia Blemker (Skeletal Muscle has a Mind of its Own: a Computational Framework to Model the Complex Process of Muscle Adaptation) and Sabrina Lee (Muscle Properties of Spastic Muscle (Stroke and CP) are summaries of their representative contributions for the session on skeletal muscle mechanics, energetics and plasticity at the 2016 Biomechanics and Neural Control of Movement Conference (BANCOM 2016)...
October 23, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29057578/label-free-imaging-of-redox-status-and-collagen-deposition-showing-metabolic-differences-in-the-heart
#17
Janna L Morrison, Alexandra Sorvina, Jack R T Darby, Christie A Bader, Mitchell C Lock, Mike Seed, Tim Kuchel, Sally E Plush, Douglas A Brooks
The heart has high metabolic demand to maintain function. The primary source of energy supply to support correct contractile muscle function differs between a fetus and an adult. In fetal life, ATP is primarily generated by glycolysis and lactate oxidation, whereas following birth there is a shift towards a reliance on mitochondrial metabolism and fatty acid oxidation. This change in metabolic status is an adaptation to different fuel availability, oxygenation and growth patterns. Here, we have employed two-photon excitation fluorescence microscopy to define the relationship between two critical metabolic co-factors NAD(P)H and FAD, effectively utilising a redox ratio to differentiate between the metabolic status in fetal (proliferative) and adult (quiescent/hypertrophic) hearts...
October 23, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29042325/characterize-a-typically-dscam-with-alternative-splicing-in-mud-crab-scylla-paramamosain
#18
Wenshi Li, Xixiang Tang, Yan Chen, Wanwei Sun, Yan Liu, Yi Gong, Xiaobo Wen, Shengkang Li
As a member of the immunoglobulin superfamily, Down syndrome cell adhesion molecule (Dscam) could function in the innate immunity of invertebrates. Recently, it is shown that arthropod Dscams play similar functions as antibodies in the adaptive immune system. Dscam could produce thousands of isoforms by alternative splicing and specifically bind to various pathogens. In the present study, we cloned the first Dscam from mud crab Scylla paramamosain (SpDscam), with full-length cDNA 7363 bp containing an open reading frame (ORF) of 6069bp and encoding 2022 amino acids, which had typical domain architecture as other arthropods, i...
October 16, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29039043/layer-dependent-role-of-collagen-recruitment-during-loading-of-the-rat-bladder-wall
#19
Fangzhou Cheng, Lori A Birder, F Aura Kullmann, Jack Hornsby, Paul N Watton, Simon Watkins, Mark Thompson, Anne M Robertson
In this work, we re-evaluated long-standing conjectures as to the source of the exceptionally large compliance of the bladder wall. Whereas these conjectures were based on indirect measures of loading mechanisms, in this work we take advantage of advances in bioimaging to directly assess collagen fibers and wall architecture during biaxial loading. A custom biaxial mechanical testing system compatible with multiphoton microscopy was used to directly measure the layer-dependent collagen fiber recruitment in bladder tissue from 9 male Fischer rats (4 adult and 5 aged)...
October 16, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29031337/physiologic-changes-of-the-musculoskeletal-system-with-aging-a-brief-review
#20
REVIEW
Walter R Frontera
Aging is one of the important challenges of modern society. Advanced adult age is associated with changes in many physiologic systems. Of particular interest is the musculoskeletal system because it directly contributes to mobility and functional independence. Skeletal muscle mass and strength decline with age. These changes are mostly due to a reduction in the number of muscle fibers and cellular and molecular changes that reduce the force-generation process. Bone mass and architecture are compromised and may result in fractures...
November 2017: Physical Medicine and Rehabilitation Clinics of North America
keyword
keyword
112870
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"