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https://www.readbyqxmd.com/read/28103455/-epidemiological-and-demographic-characteristics-of-patients-with-head-and-neck-tumours-in-the-northern-portugal-impact-on-survival
#1
Roberto Estêvão, Tiago Santos, Ana Ferreira, Anabela Machado, João Fernandes, Eurico Monteiro
INTRODUCTION: In Portugal there are still no epidemiological and demographic studies conducted in patients with of the head and neck tumors. The objectives of this analysis are to describe the epidemiological and demographics of patients with malignant tumors of the head and neck referred to an Ear, Nose and Throat department of an oncology center in the North of Portugal and also assess the impact of these characteristics on survival. MATERIAL AND METHODS: Retrospective study of patients referred between January 2011 and December 2013 to the Ear, Nose and Throat Department of an oncology center (Instituto Português de Oncologia do Porto),...
October 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28101158/prevalence-of-carbapenemases-among-high-level-aminoglycoside-resistant-acinetobacter-baumannii-isolates-in-a-university-hospital-in-china
#2
Yanhong Wang, Min Shen, Jingni Yang, Min Dai, Yaowen Chang, Chi Zhang, Guangxin Luan, Baodong Ling, Xu Jia
The prevalence of aminoglycoside resistant enzymes has previously been reported and extended-spectrum β-lactamase among Acinetobacter baumannii. To track the risk of multidrug-resistant A. baumannii, the present study aimed to determine the prevalence of carbapenemases in high-level aminoglycoside resistant A. baumannii over two years. A total of 118 strains of A. baumannii were consecutively collected in the First Affiliated Hospital of Chengdu Medical College, Chengdu, China. These isolates were investigated on the genetic basis of their resistance to aminoglycosides...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28100689/effectiveness-and-duration-of-protection-of-one-dose-of-a-meningococcal-conjugate-vaccine
#3
Amanda C Cohn, Jessica R MacNeil, Lee H Harrison, Ruth Lynfield, Arthur Reingold, William Schaffner, Elizabeth R Zell, Brian Plikaytis, Xin Wang, Nancy E Messonnier
BACKGROUND: Meningococcal conjugate vaccines were licensed beginning in 2005 on the basis of serologic end points and recommended for use in adolescents. A single dose at age 11 to 12 years was expected to provide protection through late adolescence. We conducted a case-control evaluation of vaccine effectiveness (VE) and duration of protection of a meningococcal (groups A, C, W, and Y) polysaccharide diphtheria toxoid conjugate vaccine (MenACWY-D). METHODS: Cases of culture- or polymerase chain reaction-confirmed serogroup A, C, W, and Y meningococcal disease among adolescents were identified through meningococcal disease surveillance sites in the United States from January 1, 2006, through August 31, 2013...
January 18, 2017: Pediatrics
https://www.readbyqxmd.com/read/28100229/surveillance-of-life-long-antibiotics-a-review-of-antibiotic-prescribing-practices-in-an-australian-healthcare-network
#4
Jillian S Y Lau, Christopher Kiss, Erika Roberts, Kylie Horne, Tony M Korman, Ian Woolley
BACKGROUND: The rise of antimicrobial use in the twentieth century has significantly reduced morbidity due to infection, however it has also brought with it the rise of increasing resistance. Some patients are on prolonged, if not "life-long" course of antibiotics. The reasons for this are varied, and include non-infectious indications. We aimed to study the characteristics of this potential source of antibiotic resistance, by exploring the antibiotic dispensing practices and describing the population of patients on long-term antibiotic therapy...
January 18, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28099520/oral-medications-enhance-adherence-to-surveillance-for-hepatocellular-carcinoma-and-survival-in-chronic-hepatitis-b-patients
#5
Joon Yeul Nam, Jeong-Hoon Lee, Hwi Young Kim, Jieun E Kim, Dong Hyeon Lee, Young Chang, Hyeki Cho, Jeong-Ju Yoo, Minjong Lee, Young Youn Cho, Yuri Cho, EunJu Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon
BACKGROUND/AIMS: Regular surveillance for hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients is essential to detect HCC earlier and to improve prognosis. This study investigated whether prescription of oral medication contributes to adherence to surveillance, early tumor detection, and overall survival (OS). METHODS: A total of 401 CHB patients who were newly diagnosed with HCC were included: 134 patients received no medication (group 1), 151 received hepatoprotective agents such as ursodeoxycholic acid and silymarin (group 2), and 116 received antiviral agents (group 3) at two years before HCC diagnosis...
2017: PloS One
https://www.readbyqxmd.com/read/28098539/incidence-of-norovirus-associated-diarrhea-shanghai-china-2012-2013
#6
Jianxing Yu, Chuchu Ye, Shengjie Lai, Weiping Zhu, Zike Zhang, Qibin Geng, Caoyi Xue, Weizhong Yang, Shuyu Wu, Aron J Hall, Qiao Sun, Zhongjie Li
We conducted sentinel-based surveillance for norovirus in the Pudong area of Shanghai, China, during 2012-2013, by analyzing 5,324 community surveys, 408,024 medical records, and 771 laboratory-confirmed norovirus infections among 3,877 diarrhea cases. Our analysis indicated an outpatient incidence of 1.5/100 person-years and a community incidence of 8.9/100 person-years for norovirus-associated diarrhea.
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28097680/development-of-a-novel-algorithm-for-detecting-glucocorticoid-induced-diabetes-mellitus-using-a-medical-information-database
#7
T Imatoh, K Sai, K Hori, K Segawa, J Kawakami, M Kimura, Y Saito
WHAT IS KNOWN AND OBJECTIVE: Glucocorticoid-induced diabetes mellitus (GIDM) increases the risk of diabetes mellitus (DM)-related complications but is generally difficult to detect in clinical settings. The criteria for diagnosing GIDM have not been established. Recently, medical information databases (MIDs) have been used in post-marketing surveillance (PMS) studies. We conducted a pharmacoepidemiological study to develop an algorithm for detecting GIDM using MID. METHODS: We selected 1214 inpatients who were newly prescribed with a typical glucocorticoid, prednisolone, during hospitalization from 2008 to 2014 from an MID of Hamamatsu University Hospital in Japan...
January 18, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28096903/anxiety-and-depression-symptoms-among-women-attending-group-based-patient-education-courses-for-hereditary-breast-and-ovarian-cancer
#8
Wenche Listøl, Hildegunn Høberg-Vetti, Geir Egil Eide, Cathrine Bjorvatn
BACKGROUND: Women carrying BRCA-mutations are facing significant challenges, including decision making regarding surveillance and risk-reducing surgery. They often report that they are left alone with these important decisions. In order to enhance the genetic counselling session we organized a group-based patient education (GPE) course for women with BRCA-mutations. The study aims were to characterize women attending a group-based patient education (GPE) course for hereditary breast and ovarian cancer, consider the usefulness of the course, evaluate symptoms of anxiety and depression among the participants, and finally investigate whether their levels of anxiety and depression changed from before to after the course session...
2017: Hereditary Cancer in Clinical Practice
https://www.readbyqxmd.com/read/28096455/multicenter-prospective-study-on-device-associated-infection-rates-and-bacterial-resistance-in-intensive-care-units-of-venezuela-international-nosocomial-infection-control-consortium-inicc-findings
#9
Gabriel D Empaire, Maria E Guzman Siritt, Victor D Rosenthal, Fernando Pérez, Yvis Ruiz, Claudia Díaz, Gabriela Di Silvestre, Evelyn Salinas, Nelva Orozco
BACKGROUND: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety in the intensive care unit (ICU). METHODS: A DA-HAI surveillance study was conducted by the International Nosocomial Infection Control Consortium (INICC) in two adult medical/surgical ICUs at two hospitals in Caracas, Venezuela, in different periods from March 2008 to April 2015, using the US Centers for Disease Control and Prevention's National Healthcare Safety Network (CDC/NHSN) definitions and criteria, and INICC methods...
January 2017: International Health
https://www.readbyqxmd.com/read/28095142/epidemiology-of-national-collegiate-athletic-association-women-s-lacrosse-injuries-2009-10-through-2014-15
#10
Zachary Y Kerr, Andrew E Lincoln, Shane V Caswell, David A Klossner, Nina Walker, Thomas P Dompier
CONTEXT: Participation in collegiate women's lacrosse has increased dramatically, but little recent epidemiological data exists regarding injuries. OBJECTIVE: Describe the epidemiology of National Collegiate Athletic Association (NCAA) women's lacrosse injuries during the 2009-10 through 2014-15 academic years. SETTING: Aggregate injury and exposure data collected from 40 women's lacrosse programs providing 83 team-seasons of data. PATIENTS OR OTHER PARTICIPANTS: Collegiate women's lacrosse student-athletes...
January 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28093797/adverse-reactions-to-dietary-supplements-containing-red-yeast-rice-assessment-of-cases-from-the-italian-surveillance-system
#11
Gabriela Mazzanti, Paola Angela Moro, Emanuel Raschi, Roberto Da Cas, Francesca Menniti-Ippolito
AIMS: Red yeast rice (RYR) is contained in dietary supplements for patients with dyslipidemia. RYR supplements contain monacolin K, which is chemically identical to lovastatin, a licensed drug with a well-known risk profile. We aim to describe the safety profile of RYR by analysing spontaneous reports of suspected adverse reactions (ARs). METHODS: Within the Italian Surveillance System of Natural Health Products, suspected ARs were collected and evaluated by a multidisciplinary group of experts to assess causality using the WHO-UMC system or the CIOMS/RUCAM score, for hepatic reactions...
January 17, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28091866/review-of-diagnostic-challenges-in-occupational-asthma
#12
REVIEW
Jacques A Pralong, Andre Cartier
PURPOSE OF REVIEW: Occupational asthma (OA) is one of the most frequent occupational diseases and its diagnosis is often difficult. This review summarizes its current diagnostic challenges. RECENT FINDINGS: OA is associated with significant health and socio-economic burden. It is underdiagnosed and physicians need to adopt a stepwise approach to confirm the diagnosis. Although early removal from exposure to the offending agent is associated with a better prognosis, physicians should try to confirm the diagnosis of work-related asthma before taking a worker off work...
January 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28089304/management-of-prostate-cancer-in-elderly-patients-recommendations-of-a-task-force-of-the-international-society-of-geriatric-oncology
#13
REVIEW
Jean-Pierre Droz, Gilles Albrand, Silke Gillessen, Simon Hughes, Nicolas Mottet, Stéphane Oudard, Heather Payne, Martine Puts, Gilbert Zulian, Lodovico Balducci, Matti Aapro
CONTEXT: Prostate cancer is the most frequent male cancer. Since the median age of diagnosis is 66 yr, many patients require both geriatric and urologic evaluation if treatment is to be tailored to individual circumstances including comorbidities and frailty. OBJECTIVE: To update the 2014 International Society of Geriatric Oncology (SIOG) guidelines on prostate cancer in men aged >70 yr. The update includes new material on health status evaluation and the treatment of localised, advanced, and castrate-resistant disease...
January 11, 2017: European Urology
https://www.readbyqxmd.com/read/28087585/standard-based-comprehensive-detection-of-adverse-drug-reaction-signals-from-nursing-statements-and-laboratory-results-in-electronic-health-records
#14
Suehyun Lee, Jiyeob Choi, Hun-Sung Kim, Grace Juyun Kim, Kye Hwa Lee, Chan Hee Park, Jongsoo Han, Dukyong Yoon, Man Young Park, Rae Woong Park, Hye-Ryun Kang, Ju Han Kim
OBJECTIVE: We propose 2 Medical Dictionary for Regulatory Activities-enabled pharmacovigilance algorithms, MetaLAB and MetaNurse, powered by a per-year meta-analysis technique and improved subject sampling strategy. MATRIALS AND METHODS: This study developed 2 novel algorithms, MetaLAB for laboratory abnormalities and MetaNurse for standard nursing statements, as significantly improved versions of our previous electronic health record (EHR)-based pharmacovigilance method, called CLEAR...
January 13, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28081329/daily-surveillance-with-early-warning-scores-help-predicthospital-mortality-in-medical-wards
#15
Mine Durusu Tanrıöver, Burçin Halaçlı, Bilgin Sait, Serpil Öcal, Arzu Topeli
BACKGROUND/AIM: To analyze the potency of a modified early warning score (EWS) to help predict hospital mortality when used for surveillance in nonacute medical wards. MATERIALS AND METHODS: Patients in internal medicine wards were prospectively recruited. First, highest, and last scores; and mean daily score recordings and values were recorded. Nurses calculated scores for each patient upon admission and every 4 h. The last score was the score before death, discharge, or transfer to another ward...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28080959/sentinel-surveillance-of-imported-dengue-via-travellers-to-europe-2012-to-2014-tropnet-data-from-the-denguetools-research-initiative
#16
Andreas Neumayr, Jose Muñoz, Mirjam Schunk, Emmanuel Bottieau, Jakob Cramer, Guido Calleri, Rogelio López-Vélez, Andrea Angheben, Thomas Zoller, Leo Visser, Núria Serre-Delcor, Blaise Genton, Francesco Castelli, Marjan Van Esbroeck, Alberto Matteelli, Laurence Rochat, Elena Sulleiro, Florian Kurth, Federico Gobbi, Francesca Norman, Ilaria Torta, Jan Clerinx, David Poluda, Miguel Martinez, Antonia Calvo-Cano, Maria Paz Sanchez-Seco, Annelies Wilder-Smith, Christoph Hatz, Leticia Franco
We describe the epidemiological pattern and genetic characteristics of 242 acute dengue infections imported to Europe by returning travellers from 2012 to 2014. The overall geographical pattern of imported dengue (South-east Asia > Americas > western Pacific region > Africa) remained stable compared with 1999 to 2010. We isolated the majority of dengue virus genotypes and epidemic lineages causing outbreaks and epidemics in Asia, America and Africa during the study period. Travellers acted as sentinels for four unusual dengue outbreaks (Madeira, 2012-13; Luanda, 2013; Dar es Salaam, 2014; Tokyo, 2014)...
January 5, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28079746/sentinel-surveillance-for-expedited-partner-therapy-prescriptions-using-pharmacy-data-in-2-new-york-city-neighborhoods-2015
#17
Ebiere Okah, Vibhuti Arya, Meighan Rogers, Michelle Kim, Julia Ann Schillinger
BACKGROUND: Expedited partner therapy (EPT) for Chlamydia trachomatis (Ct) is the practice of providing Ct-infected patients with medication, or prescription (prescription-EPT) to deliver to their sex partners without first examining those partners. New York City (NYC) providers commonly use prescription-EPT, yet NYC pharmacists report only occasional receipt of EPT prescriptions. This project assessed the frequency of EPT prescriptions filled in 2 NYC neighborhoods. METHODS: The 2 NYC facilities reporting the most frequent use of prescription-EPT were identified from Ct provider case reports and contacted to ascertain their EPT practices...
February 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28079643/validation-of-retention-in-hiv-care-status-using-the-new-york-city-hiv-surveillance-registry-and-clinical-care-data-from-a-large-hiv-care-center
#18
Rituparna Pati, Rebekkah S Robbins, Sarah L Braunstein
CONTEXT: Improving retention in care is a key element of the National HIV/AIDS Strategy (NHAS). However, definitions for measuring retention in care are not standardized. OBJECTIVE: To compare measures of retention based on both clinic visit data and HIV laboratory surveillance data. DESIGN: Retrospective cohort study. SETTING: New York City (NYC), New York. PARTICIPANTS: We matched adult patients with HIV infection seen at the Spencer Cox Center for Health (SCC) in 2010 or 2011 with the NYC HIV Surveillance Registry...
January 11, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28079594/impact-of-concurrent-medication-use-on-pancreatic-cancer-survival-seer-medicare-analysis
#19
Muhammad S Beg, Arjun Gupta, David Sher, Sadia Ali, Saad Khan, Ang Gao, Tyler Stewart, Chul Ahn, Jarett Berry, Eric M Mortensen
OBJECTIVES: Preclinical studies have suggested that non-antineoplastic medication use may impact pancreatic cancer biology. We examined the association of several medication classes on pancreatic cancer survival in a large medical claims database. MATERIALS AND METHODS: Histologically confirmed pancreatic adenocarcinoma diagnosed between 2006 and 2009 were analyzed from the Surveillance, Epidemiology, and End Results-Medicare database with available part D data...
January 10, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28078665/computerized-pharmacy-surveillance-and-alert-system-for-drug-related-problems
#20
O Ferrández, O Urbina, S Grau, J Mateu-de-Antonio, M Marin-Casino, J Portabella, S Mojal, M Riu, E Salas
WHAT IS KNOWN AND OBJECTIVE: Because of the impact of drug-related problems (DRPs) on morbidity and mortality, there is a need for computerized strategies to increase drug safety. The detection and identification of the causes of potential DRPs can be facilitated by the incorporation of a pharmacy warning system (PWS) in the computerized prescriber order entry (CPOE) and its application in the routine validation of inpatient drug therapy. A limited number of studies have evaluated a clinical decision support system to monitor drug treatment...
January 12, 2017: Journal of Clinical Pharmacy and Therapeutics
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