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electromechanical delay and stroke

Marta Gandolla, Simona Ferrante, Giancarlo Ferrigno, Davide Baldassini, Franco Molteni, Eleonora Guanziroli, Michele Cotti Cottini, Carlo Seneci, Alessandra Pedrocchi
OBJECTIVE: To design and implement an electromyography (EMG)-based controller for a hand robotic assistive device, which is able to classify the user's motion intention before the effective kinematic movement execution. METHODS: Multiple degrees-of-freedom hand grasp movements (i.e. pinching, grasp an object, grasping) were predicted by means of surface EMG signals, recorded from 10 bipolar EMG electrodes arranged in a circular configuration around the forearm 2-3 cm from the elbow...
September 27, 2016: Journal of International Medical Research
Serkan Ozturk, Selçuk Öztürk, Fatma Hizal Erdem, Alim Erdem, Selim Ayhan, İbrahim Dönmez, Mehmet Yazıcı
AIM: Heart rate (HR) reduction with ivabradine improves left ventricle filling by the prolongation of the diastolic time and increases stroke volume. But, it remains unclear what ivabradine's effect is on atrial conduction time and atrial mechanical functions. The aim of our study was to evaluate in stable outpatients with systolic heart failure (HF) the 3 months effect of ivabradine on atrial conduction time and mechanical functions. METHOD: We evaluated prospectively 43 (31 males, 12 females) patients with HF...
September 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Nermin Bayar, Çağın Mustafa Üreyen, Zehra Erkal, Selçuk Küçükseymen, Serkan Çay, Göksel Çağırcı, Şakir Arslan
OBJECTIVE: This study aimed to evaluate the association between the history of stroke/transient ischemic attack (TIA) and inter- and intra-atrial electromechanical delay (EMD) in patients with paroxysmal atrial fibrillation (PAF). METHODS: Patients diagnosed with PAF were included in this retrospective study. Patients who had a history of stroke or TIA were defined as the symptomatic group, whereas those who did not have such a history were defined as the asymptomatic group...
August 2016: Anatolian Journal of Cardiology
Sophie C H Van Malderen, Dirk Kerkhove, Dominic A M J Theuns, Caroline Weytjens, Steven Droogmans, Kaoru Tanaka, Dorien Daneels, Sonia Van Dooren, Marije Meuwissen, Maryse Bonduelle, Pedro Brugada, Guy Van Camp
BACKGROUND AND OBJECTIVES: Right ventricular (RV) conduction delay has been suggested as an underlying pathophysiological mechanism in Brugada syndrome (BS). In this cross-sectional study we non-invasively assessed the value of echocardiographic markers reflecting ventricular ejection delay to further assess electromechanical abnormalities in BS and to identify patients at risk for life-threatening arrhythmic events. Furthermore, we sought to assess differences in ejection delays between genders because male BS patients demonstrate a more malignant clinical phenotype...
July 15, 2015: International Journal of Cardiology
Mehmet Bülent Vatan, Sabiye Yılmaz, Mustafa Tarık Ağaç, Mehmet Akif Çakar, Hakan Erkan, Murat Aksoy, Saadet Demirtas, Ceyhun Varım, Ramazan Akdemir, Hüseyin Gündüz
BACKGROUND: CHA2DS2-VASc score is the most widely preferred method for prediction of stroke risk in patients with atrial fibrillation. We hypothesized that CHA2DS2-VASc score may represent atrial remodeling status, and therefore echocardiographic evaluation of left atrial electromechanical remodeling can be used to identify patients with high risk. METHODS: A total of 65 patients who had documented diagnosis of paroxysmal atrial fibrillation (PAF) were divided into three risk groups according to the CHA2DS2-VASc score: patients with low risk (score=0, group 1), with moderate risk (score=1, group 2), and with high risk score (score ≥2, group 3)...
November 2015: Journal of Cardiology
Yi-Chih Wang, Chih-Chieh Yu, Fu-Chun Chiu, Vincent Splett, Ruth Klepfer, Kathryn Hilpisch, Chia-Ti Tsai, Ling-Ping Lai, Juey-Jen Hwang, Jiunn-Lee Lin
OBJECTIVES: We tested the acute effects of resynchronization in heart failure patients with a normal (>50%) left ventricular (LV) ejection fraction (HFNEF) and mechanical dyssynchrony. METHODS: Twenty-four HFNEF patients (72 ± 6 years, 5 male) with mechanical dyssynchrony (standard deviation of electromechanical time delay among 12 LV segments >35 ms) were studied with temporary pacing catheters in the right atrium, LV, and right ventricle (RV), and high-fidelity catheters for pressure recording...
2015: Cardiology
Mehmet Ata Akıl, Eşref Akıl, Mehmet Zihni Bilik, Mustafa Oylumlu, Halit Acet, Abdülkadir Yıldız, Abdurrahman Akyüz, Faruk Ertaş, Nizamettin Toprak
OBJECTIVE: The aim of this study was to evaluate the relationship between atrial electromechanical delay (EMD) measured with tissue Doppler imaging (TDI) and left atrial (LA) mechanical functions in patients with ischemic stroke and compare them with healthy controls. METHODS: Thirty patients with ischemic stroke were enrolled into this cross-sectional, observational study. The control group consisted of 35 age- and gender-matched apparently healthy individuals patients...
July 2015: Anatolian Journal of Cardiology
Grant V Chow, Michael G Silverman, Richard S Tunin, Albert C Lardo, Saman Nazarian, David A Kass
BACKGROUND: Patients with acute myocardial infarction (MI), left bundle branch block (LBBB), and marked left ventricular (LV) decompensation suffer from nearly 50% early mortality. Whether cardiac resynchronization therapy (CRT) improves hemodynamic status in this condition is unknown. We tested CRT in this setting by using a canine model of delayed lateral wall (LW) activation combined with 2 hours of coronary artery occlusion-reperfusion. OBJECTIVE: This study aimed to evaluate the acute hemodynamic effects of CRT during and immediately after MI...
October 2014: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Francois Haddad, Julien Guihaire, Mehdi Skhiri, Andre Y Denault, Olaf Mercier, Shadi Al-Halabi, Bojan Vrtovec, Elie Fadel, Roham T Zamanian, Ingela Schnittger
AIMS: The objective of this study was to determine the factors independently associated with septal curvature in patients with pulmonary arterial hypertension (PAH). METHODS: Eighty-five consecutive patients with PAH who had an echocardiogram and a right heart catheterization within 24 hours of each others were included in the study. Septal curvature was assessed at the mid-papillary level using the eccentricity index (EI). Marked early systolic septal anterior motion was defined as a change in EI > 0...
July 2014: Echocardiography
Marc J van Houwelingen, Daphne Merkus, Jan Hofland, Jan Bakker, Robert Tenbrinck, Maaike Te Lintel Hekkert, Geert van Dijk, Arnold P G Hoeks, Dirk J Duncker
Recently, the ventilatory variation in pre-ejection period (ΔPEP) was found to be useful in the prediction of fluid-responsiveness of patients in shock. In the present study we investigated the behavior of the ventilation-induced variations in the systolic timing intervals in response to a graded hemorrhage protocol. The timing intervals studied included the ventilatory variation in ventricular electromechanical delay (ΔEMD), isovolumic contraction period (determined from the arterial pressure waveform, ΔAIC), pulse travel time (ΔPTT), and ΔPEP...
December 2013: American Journal of Physiology. Heart and Circulatory Physiology
Jimson Ngeo, Tomoya Tamei, Tomohiro Shibata, M F Felix Orlando, Laxmidhar Behera, Anupam Saxena, Ashish Dutta
Patients suffering from loss of hand functions caused by stroke and other spinal cord injuries have driven a surge in the development of wearable assistive devices in recent years. In this paper, we present a system made up of a low-profile, optimally designed finger exoskeleton continuously controlled by a user's surface electromyographic (sEMG) signals. The mechanical design is based on an optimal four-bar linkage that can model the finger's irregular trajectory due to the finger's varying lengths and changing instantaneous center...
2013: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Yuxuan Hu, Viatcheslav Gurev, Jason Constantino, Natalia Trayanova
BACKGROUND: The acute response to cardiac resynchronization therapy (CRT) has been shown to be due to 3 mechanisms: resynchronization of ventricular contraction, efficient preloading of the ventricles by a properly timed atrial contraction, and mitral regurgitation reduction. However, the contribution of each of the 3 mechanisms to the acute response to CRT, specifically stroke work improvement, has not been quantified. OBJECTIVE: To use a magnetic resonance image-based anatomically accurate 3-dimensional model of failing canine ventricular electromechanics to quantify the contribution of each of the 3 mechanisms to stroke work improvement and identify the predominant mechanisms...
December 2013: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Cinzia Valzania, Maria J Eriksson, Mauro Biffi, Giuseppe Boriani, Fredrik Gadler
PURPOSE: Quadripolar left ventricular (LV) leads allow for several pacing configurations in candidates for cardiac resynchronization therapy (CRT). Whether different pacing configurations may affect LV dyssynchrony and systolic function is not completely known. We aimed to evaluate the acute effects of different pacing vectors on LV electromechanical parameters in patients implanted with a quadripolar LV lead. METHODS: In this two-centre study, within 1 month of implantation 21 CRT patients (65 ± 8 years, 76 % men, 38 % ischemic) receiving a quadripolar LV lead (Quartet 1458Q, St Jude Medical) underwent LV capture threshold assessment, intracardiac electrogram optimization, and two-dimensional echocardiography during four pacing configurations: D1-P4, P4-RV coil, D1-RV coil, and P4-M2...
October 2013: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Yi-Chih Wang, Chih-Chieh Yu, Fu-Chun Chiu, Chia-Ti Tsai, Ling-Ping Lai, Juey-Jen Hwang, Jiunn-Lee Lin
BACKGROUND: The association between diastolic abnormality and postexercise contractile decompensation is uncertain in heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF). HYPOTHESIS: The higher mitral E/annular early diastolic velocity (E/e') is relevant to postexercise regional myocardial contractile maladaptation. METHODS: Seventy HF patients with LVEF <50 % (56 males, 58 ± 15 years) were studied pre- and postexercise using tissue Doppler echocardiography...
August 2013: Clinical Cardiology
Chien-Jung Chang, Yao-Chang Chen, Yung-Kuo Lin, Jen-Hung Huang, Shih-Ann Chen, Yi-Jen Chen
BACKGROUND: Rivaroxaban reduces stroke in patients with atrial fibrillation (AF). Left atrium (LA) plays a critical role in the pathophysiology of AF. However, the electromechanical effects of rivaroxaban on LA are not clear. RESULTS: Conventional microelectrodes and a whole-cell patch-clamp were used to record the action potentials (APs) and ionic currents in rabbit LA preparations and isolated single LA cardiomyocytes before and after the administration of rivaroxaban...
2013: Journal of Biomedical Science
Ahmet Akyel, Yusuf Tavil, Abdurrahman Tufan, Cagri Yayla, Arif Kaya, Mehme Engin Tezcan, Mehmet Akif Ozturk, Bulent Boyaci
PURPOSE: In this study we aimed to investigate myocardial function and atrial electromechanical properties by conventional and tissue doppler echocardiography in patients with primary Sjögren syndrome. METHODS: Forty patients with Sjögren syndrome (SS) and 25 age- and sex-matched healthy volunteers were enrolled in the study. Using transthoracic echocardiography, myocardial performance index and atrial electromechanical properties were measured. RESULTS: Basal characteristics were similar between two groups...
2012: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
Lovely Chhabra, Indu Srinivasan, Pooja Sareen, Curuchi Anand, David H Spodick
Interatrial block (IAB; P-wave duration ≥110 milliseconds) denotes a conduction delay between the two atria. IAB has been shown to have a strong correlation with atrial arrhythmias, left atrial enlargement, left atrial electromechanical dysfunction and cerebral thromboembolism. Our study sought to determine whether there was an increased incidence of IAB in patients with acute occlusive mesenteric ischemia. Medical records of patients admitted with a diagnosis of acute mesenteric ischemia (AMeI) from January 2009 to March 2011 were reviewed retrospectively...
July 2012: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Yi-Chih Wang, Chih-Chieh Yu, Fu-Chun Chiu, Ruth Klepfer, Kathryn Hilpisch, Vincent Splett, Chia-Ti Tsai, Ling-Ping Lai, Juey-Jen Hwang, Jiunn-Lee Lin
BACKGROUND: We hypothesized left ventricular (LV) dyssynchrony would affect postexercise accommodation of regional myocardial motion in patients with heart failure and a normal ejection fraction (HFNEF). METHODS AND RESULTS: Tissue-Doppler echocardiography was studied in 100 hypertensive patients with LV ejection fraction >50%. Among them, 70 HFNEF patients were classified into the systolic dyssynchrony (Dys: >65 ms difference of electromechanical delay between septal and lateral segments) (43 patients) and nondyssynchrony (Ndys: 27 patients) groups, and the other 30 patients were as the control (Ctrl)...
February 2012: Journal of Cardiac Failure
Islam Abd Elmoneem Elsherbiny
BACKGROUND: Arterial stiffness is strongly predictive for cardiovascular events in hypertensive individuals and it may increase the risk of stroke. This study was designed to evaluate the possible relationship between arterial stiffness and atrial electromechanical delay and P wave dispersion (PWD), as determinants of AF risk. MATERIALS AND METHODS: The study included 75 hypertensive patients and 45 healthy control subjects. Atrial electromechanical coupling (time interval from the onset of P wave on ECG to the beginning of A wave with tissue Doppler echocardiography [PA]), intraatrial and interatrial electromechanical delay (EMD) and PWD were measured...
2012: Internal Medicine
Fang Wang, Haoying Shi, Yaping Sun, Jufang Wang, Qing Yan, Wei Jin, Jianjun Zhang, Weidong Meng, Feng Zhang, Gang Chen, Baogui Sun
AIMS: This study aimed to explore if the right ventricular outflow tract (RVOT) pacing is superior to right ventricular apical (RVA) pacing on the overall left ventricular (LV) function and regional wall motion. METHODS AND RESULTS: Sixty patients with atrio-ventricular (AV) block and normal ejection fraction undergoing dual-chamber pacemaker implantation were randomized to permanent ventricular stimulation either in the RVOT or the RVA. Left ventricular volume, ejection fraction, and LV regional wall motion were assessed by echocardiography...
March 2012: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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