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transcutaneous bilirubin

Mor Cucuy, Ada Juster-Reicher, Orna Flidel, Eric Shinwell
BACKGROUND: Transcutaneous bilirubinometry (TcB) is routinely used to monitor jaundice in term and near-term infants. However, before 35 weeks gestation, the technique has not been widely adopted. AIM: The aim of this study is to study the correlation between TcB and total serum bilirubin (TsB) before, during, and after phototherapy in preterm infants born before 35 weeks' gestation. METHODS: Jaundice was monitored in infants born before 35 weeks' gestation by simultaneous measurements of TsB and TcB assessed by a Drager Jaundice Meter JM-103 (Draeger Medical, Inc...
April 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
Pareshkumar Thakkar, Hardas Chavda, Vikas Doshi
OBJECTIVE: To develop nomogram of Transcutaneous Bilirubin among healthy term and late-preterm neonates during first 96 hours of age. OBJECTIVE: HASH(0x39b5560) DESIGN: Prospective longitudinal study. SETTING: Neonatal unit of a tertiary care Hospital of Central Gujarat, India. PARTICIPANTS: 1075 healthy term and late preterm neonates (≥35weeks). INTERVENTION: Six-hourly transcutaneous bilirubin was obtained from birth to 96 hour of life using Drager JM 103 Transcutaneous Bilirubinometer...
March 29, 2017: Indian Pediatrics
Denise F Jones, Abigail R McRea, James D Knowles, Feng-Chang Lin, Erin Burnette, Lara A Reller, Jacob A Lohr
The American Academy of Pediatrics recommends screening newborns ≥35 weeks' gestation with total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) to detect hyperbilirubinemia. Retrospective studies show TcB measurements strongly correlate with TSB; however, few prospective trials document this relationship. Furthermore, Dräger's newest TcB instrument, JM-105, remains unstudied in the United States. We measure TcB on foreheads and sternums of newborns using JM-105 and Bilichek devices within 30 minutes of TSB measurement...
March 1, 2017: Clinical Pediatrics
Li Wang, Arianne Y K Albert, Benjamin Jung, Keyvan Hadad, Martha E Lyon, Melanie Basso
BACKGROUND: Neonatal hyperbilirubinemia has traditionally been screened by either total serum bilirubin or transcutaneous bilirubin. Whole blood bilirubin (TwB) by the GEM Premier 4000® blood gas analyzer (GEM) is a relatively new technology and it provides fast bilirubin results with a small sample volume and can measure co-oximetry and other analytes. Our clinical study was to evaluate the reliability of TwB measured by the GEM and identify analytical and clinical factors that may contribute to possible bias...
March 29, 2017: BMC Pediatrics
K L Fine, W A Carey, J A W Schuster, S C Bryant, W J Cook, B S Karon
OBJECTIVE: The objective of this study is to determine the impact of postnatal age on the bias between transcutaneous (TcB) and total serum bilirubin (TSB), and evaluate a TcB screening protocol. STUDY DESIGN: Preterm and term infants had paired TcB and TSB performed on days 1 to 3 of life; a subset of preterm infants had measurements on days 4 to 7. Sensitivity and specificity of TcB (plotted on an age-specific TSB nomogram) for prediction of high-intermediate (HIR) or high-risk TSB were calculated...
February 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
Bolajoko O Olusanya, Cecilia A Mabogunje, Donald O Imosemi, Abieyuwa A Emokpae
BACKGROUND: The use of transcutaneous bilirubin (TcB) as a screening tool, based on relevant population-specific nomogram, or proxy for total serum bilirubin (TSB) levels in assessing the risk of subsequent hyperbilirubinemia is supported by several clinical guidelines on the management of neonatal hyperbilirubinemia. However, while TcB has been found to significantly over-estimate TSB in neonates of African-American ancestry, with variations across TcB devices, no nomogram has been specifically reported for this racial group...
2017: PloS One
Yoshinori Katayama, Masahiro Enomoto, Shin Kikuchi, Atsuko Takei, Hitoshi Ikegami, Hirotaka Minami, Yong Kye Lee
BACKGROUND: We tested whether direct transcutaneous bilirubin (TcB) measurement from an area unexposed to phototherapy is reliable to estimate total serum bilirubin (TSB) in neonates during phototherapy and whether it contributes to a reduction in TSB blood sampling when deciding to discontinue phototherapy. METHODS: We performed a retrospective observational study in term neonates who received phototherapy in the mother's room. TSB and TcB from the neonate's sternum were measured before and during phototherapy and compared with a linear regression analysis and a Bland-Altman plot, respectively...
January 24, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
Bolajoko O Olusanya, Abieyuwa A Emokpae
BACKGROUND: Routine and timely determination of total serum bilirubin (TSB) remains a challenge in many resource-limited countries with substantial burden of severe neonatal hyperbilirubinemia. Limited evidence exists on the potential usefulness of transcutaneous bilirubin (TcB) to identify infants who may require phototherapy based on possible treatment criteria in such settings. OBJECTIVE: To compare the number of infants requiring phototherapy across different TSB criteria and determine the predictive performance of TcB under each criterion...
January 11, 2017: Neonatology
D D Zhao, D Huang, X Y Gao
No abstract text is available yet for this article.
January 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Kalpana Bhardwaj, Tiffany Locke, Anne Biringer, Allyson Booth, Elizabeth Kathleen Darling, Shelley Dougan, Jane Harrison, Stephen Hill, Ana Johnson, Susan Makin, Beth Potter, Thierry Lacaze-Masmonteil, Julian Little
hyperbilirubinemia [2], every newborn should be assessed for the risk of developing severe hyperbilirubinemia with the help of predischarge total serum bilirubin or transcutaneous bilirubin measurements and/or assessments of clinical risk factors. The aim of this rapid review is 1) to review the evidence for 1) predicting and preventing severe hyperbilirubinemia and bilirubin encephalopathy, 2) determining the efficacy of home/community treatments (home phototherapy) in the prevention of severe hyperbilirubinemia, and 3) non-invasive/transcutaneous methods for estimating serum bilirubin level...
January 10, 2017: Current Pediatric Reviews
Bernice van den Esker-Jonker, Lieve den Boer, Rianne M C Pepping, Jolita Bekhof
BACKGROUND: For evaluation of jaundiced neonates, serum bilirubin (SB) or transcutaneous bilirubinometry (TcB) is used. Few data are available on the quantitative reduction of blood sampling by using TcB. METHODS: We conducted a randomized controlled trial in hospitalized jaundiced neonates ≥32 weeks' gestational age. In the intervention group, TcB was used and in the control group the decision to obtain a blood sample for SB was based on visual and clinical assessment...
December 2016: Pediatrics
Manish Jain, Akash Bang, Anju Tiwari, Shuchi Jain
BACKGROUND: Neonatal jaundice is a common problem. We evaluated the utility and best cut-off values of 24-and 48-hour transcutaneous bilirubin indices (TcBI) in predicting subsequent significant hyperbilirubinemia and evaluated various associated maternal and fetal risk factors. METHODS: TcBI at 24 and 48 hours and serum bilirubin levels at 72 hours of age were obtained for healthy, term, appropriate for gestational age neonates. Neonates with prematurity, birth weight <2500 g, ABO or Rh incompatibility, onset of clinical jaundice <24 hours, clinical suspicion of septicemia, positive pressure ventilation at birth, admission in neonatal intensive care unit and contraindications for BiliChek were excluded...
November 23, 2016: World Journal of Pediatrics: WJP
L Murli, A Thukral, M J Sankar, S Vishnubhatla, A K Deorari, V K Paul, A Sakariah, Dolma, R Agarwal
OBJECTIVE: To determine the agreement between transcutaneous bilirubin (TcB) measured from shielded skin and serum total bilirubin (STB) in infants (34 to 41 weeks of gestation) with hyperbilirubinemia receiving phototherapy (PT). STUDY DESIGN: In this prospective cohort study, we shielded a small area of skin on sternum using a commercial photo-opaque patch (BilEclipseTM, Philips Respironics, Murrysville, PA, USA). The TcB from the shielded skin (TcBs) and STB were measured at four time points-before initiation, 12 and 24 h during and once after (12 h) cessation of PT...
October 20, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Bolajoko O Olusanya, Donald O Imosemi, Abieyuwa A Emokpae
BACKGROUND AND OBJECTIVE: Transcutaneous bilirubin (TcB) correlates positively with total serum bilirubin (TSB) across different racial populations. However, little is known about the pattern of divergence between TcB and TSB at individual patient-level and the relationship with TcB measuring techniques among African neonates. This study, therefore, investigates TcB-TSB discrepancies and the contribution of 2 models of transcutaneous bilirubinometers to the observed divergence in a black African population...
September 2016: Pediatrics
Z H Rong, F Luo, L Y Ma, L Chen, L Wu, W Liu, L Z Du, X P Luo
OBJECTIVE: To verify the accuracy of a smart phone software application, which is an automated image-based bilirubin (AIB) testing technique for testing peripheral blood total bilirubin (TB) in term and late preterm neonates. METHOD: During July 2015 to January 2016, jaundiced neonates were enrolled from department of neonatology in Tongji Hospital, Children's Hospital of Zhejiang University School of Medicine and Shenzhen Bao'an Maternal and Child Health Hospital...
August 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Amandine Rubio, Chloé Epiard, Maya Gebus, Michel Deiber, Sylvain Samperiz, Céline Genty, Anne Ego, Thierry Debillon
BACKGROUND: Transcutaneous bilirubin (TcB) is a validated test for systematic screening of neonatal hyperbilirubinemia and monitoring term and near-term infants under phototherapy. OBJECTIVES: To evaluate TcB diagnostic accuracy for very preterm neonates. METHODS: Total serum bilirubin (TSB) and TcB measurements were performed prospectively in a multicenter sample of newborns <30 weeks of gestational age (GA). TcB sensitivity, specificity, predictive values, and likelihood ratios for the detection of neonates requiring phototherapy were calculated over the first 15 days of life, with or without phototherapy, with the expectation of achieving a detection rate of hyperbilirubinemia of over 95%...
2017: Neonatology
Ruben Bromiker, Barbara Medoff-Cooper, Hadar Flor-Hirsch, Michael Kaplan
BACKGROUND: Mothers of hyperbilirubinemic newborns frequently report to us that their infant is feeding poorly. As poor feeding in an extremely hyperbilirubinemic newborn may be an early sign of bilirubin encephalopathy, we hypothesized that neonatal hyperbilirubinemia would suppress the volume of feed ingested and diminish sucking parameters in comparison with minimally jaundiced neonates. OBJECTIVE: To determine whether hyperbilirubinemia does diminish feeding and sucking in neonates...
August 2016: Early Human Development
Serdar Umit Sarici, Omer Gunes, Esad Koklu, Muhittin A Serdar
OBJECTIVE: We aimed to develop a transcutaneous bilirubin (TcB) nomogram for assessment of the risk of significant hyperbilirubinemia and prolonged jaundice during the first month of life in term and late-preterm Turkish newborns. METHODS: On the basis of the daily (3rd, 7th, 15th and 30th days) TcB measurements, 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentiles, and 5 percentile tracks were obtained. TcB measurements were made by a transcutaneous bilirubinometer (JaundiceDetector JH20-1C)...
February 2017: Journal of Tropical Pediatrics
Ghulam Nabi, Saad Alsaedi
[No Abstract Available].
July 2016: Saudi Medical Journal
L Casnocha Lucanova, K Matasova, M Zibolen, P Krcho
OBJECTIVE: We tested the accuracy of transcutaneous bilirubin (TcB) measure in newborns undergoing phototherapy. STUDY DESIGN: In a prospective study of 150 term Caucasian neonates, 255 measurements of total serum bilirubin (TSB) and TcB concentration were obtained 2 h after discontinuing phototherapy. TcB measurements obtained on the forehead, sternum, abdomen and covered lower abdomen were statistically compared with the corresponding TSB. RESULT: TcB consistently underestimated TSB levels significantly...
October 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
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