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https://www.readbyqxmd.com/read/28723743/analysis-of-hpv-distribution-in-patients-with-cervical-precancerous-lesions-in-western-china
#1
Kemin Li, Rutie Yin, Qingli Li, Danqing Wang
Cervical human papillomavirus (HPV) infection is a dangerous disease, whose subtypes exhibit different distribution patterns in particular countries, regions, and races. In this study, the HPV distribution in patients with cervical precancerous lesions in Western China was investigated to assess a probability for prevention of cervical cancer and the clinical application of an HPV vaccine in China. The retrospective study of patients with different HPV subtypes and cervical precancerous lesions, who have undergone loop eelectrosurgical excision procedure, cold knife conization, or a total hysterectomy in our hospital from January 2016 to August 2016, was performed...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28578185/management-of-low-grade-cervical-mullerian-adenosarcoma-in-a-14-year-old-girl
#2
Julia K Shinnick, Natasha Kumar, Lindsey Beffa, Katherine Miller, Mary Alexandra M Friedman, Elizabeth Kalife, Paul DiSilvestro, Cara Mathews
BACKGROUND: Mullerian adenosarcomas of the cervix are composed of benign epithelial and malignant stromal components. The purpose of this report is to describe the clinical and histologic difficulties in diagnosis and to propose fertility preserving management of low grade lesions. CASE: A 14-year-old girl presented with a friable lesion found to originate from the anterior cervical lip. Initially, clinical suspicion was for sarcoma botryoides, however, pathologic evaluation revealed a low grade cervical Mullerian adenosarcoma...
May 31, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28511455/cervical-conization-and-the-risk-of-preterm-birth-a-population-based-multicentric-trial-of-turkish-cohort
#3
Ali Galip Zebitay, Emre Sinan Güngör, Gülsah Ilhan, Orkun Çetin, Cem Dane, Canan Furtuna, Fatma Ferda Verit Atmaca, Merve Tuna
INTRODUCTION: Cold Knife Conization (CKC) is one of the most effective methods for the treatment of Cervical Intraepithelial Neoplasia (CIN). Some studies showed a relation between preterm birth and the treatment of CIN; on the other hand, other studies do not show such a relationship. AIM: The present study was conducted with the aim to investigate the pregnancy outcomes of Turkish women regarding demographic characteristics, obstetric history, removed tissue, and residual cervical length after CKC and to determine the effect of removed cervical tissue volume and height on preterm birth...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28125627/comparison-of-cold-knife-conization-versus-loop-electrosurgical-excision-for-cervical-adenocarcinoma-in-situ-acis-a-systematic-review-and-meta-analysis
#4
REVIEW
Yanming Jiang, Changxian Chen, Li Li
OBJECTIVE: The objective of this systematic review was to conduct a more comprehensive literature search and meta-analysis of original studies to evaluate the efficacy and safety of the loop electrosurgical excision procedure (LEEP) versus cold-knife conization (CKC) in conservative surgical treatment of cervical adenocarcinoma in situ (ACIS) for women who have not completed childbearing. METHODS: Systematic searches were conducted in the PUBMED, EMBASE, Cochrane, and China National Knowledge Infrastructure (CNKI) databases to identify all potential studies involving patients with ACIS treated with LEEP versus CKC published until December 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28109160/antibiotics-for-infection-prevention-after-excision-of-the-cervical-transformation-zone
#5
REVIEW
Chumnan Kietpeerakool, Bandit Chumworathayi, Jadsada Thinkhamrop, Butsakorn Ussahgij, Pisake Lumbiganon
BACKGROUND: Excision of the transformation zone of the cervix is the most commonly used approach to treat cervical precancerous lesions (cervical intraepithelial neoplasia (CIN)) to reduce the risk of developing cervical cancer. As the excision of the transformation zone leaves a raw area on the cervix, there is a risk of infection following the procedure. The incidence of infection after cold knife conization (CKC) is 36%, whereas the incidence for large loop excision of the transformation zone (LLETZ, also known as loop electrical excision procedure (LEEP)) is much lower (0...
January 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28099704/high-risk-human-papillomavirus-infection-clearance-following-conization-among-patients-with-cervical-intraepithelial-neoplasm-grade-3-aged-at-least-45%C3%A2-years
#6
Guorui Zhang, Jinghe Lang, Keng Shen, Lan Zhu, Yang Xiang
OBJECTIVE: To investigate high-risk human papillomavirus (HPV) infection clearance rates following successful cold knife conization and factors predictive of HPV clearance among patients with cervical intraepithelial neoplasm grade 3. METHOD: The present retrospective study analyzed clinical data from patients aged at least 45 years with cervical intraepithelial neoplasm grade 3 who had undergone successful cold knife conization and attended regular follow-up at Peking Union Medical College Hospital, China, between January 1, 2002 and December 31, 2012...
January 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27984378/analysis-of-conservative-surgical-treatment-and-prognosis-of-microinvasive-squamous-cell-carcinoma-of-the-cervix-stage-ia1-results-of-follow-up-to-20-years
#7
Caio Augusto Hartman, Julio Cesar Teixeira, Sergio Bruno Barbosa, Stephanye Mariano Figueiredo, Liliana Aparecida Lucci De Angelo Andrade, Joana Froes Bragança Bastos
OBJECTIVE: The aim of this study was to evaluate the prognosis and recurrence of microinvasive squamous cervical (MIC) cancer stage IA1 in women treated conservatively or by hysterectomy, and followed-up to 20 years. METHODS: It was studied in a cohort of 139 women with MIC, 41 definitively managed by conization and 98 by hysterectomy from January 1994 to December 2003 and followed-up until 2013. The definitive treatment, age, conization technique (loop electrosurgical excision procedure or cold knife conization), cone margin, residual disease in hysterectomy specimen, and the association with recurrence (intraepithelial cervical neoplasia grade 3/intraepithelial vaginal neoplasia grade 3 or worse, and microinvasive or worse) were analyzed...
February 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27977541/loop-electrosurgical-excision-procedure-instead-of-cold-knife-conization-for-cervical-intraepithelial-neoplasia-in-women-with-unsatisfactory-colposcopic-examinations-a-systematic-review-and-meta-analysis
#8
REVIEW
Sherif A El-Nashar, Sherif A Shazly, Matthew R Hopkins, Jamie N Bakkum-Gamez, Abimbola O Famuyide
OBJECTIVES: This meta-analysis compared loop electrosurgical excision procedure (LEEP) with cold-knife conization (CKC) for treating cervical intraepithelial neoplasia (CIN) in patients with unsatisfactory colposcopic examinations. MATERIAL AND METHODS: A literature search on MEDLINE, EMBASE, Cochrane Systematic Reviews, CENTRAL, Web of Science, and Scopus databases was conducted from inception until April 2015. We included clinical trials and cohort studies comparing CKC with LEEP for treating CIN...
April 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27824756/adverse-pregnancy-outcomes-after-treatment-for-cervical-intraepithelial-neoplasia
#9
Tone Bjørge, Gry B Skare, Line Bjørge, Ameli Tropé, Stefan Lönnberg
OBJECTIVE: To explore associations between specific treatments for intraepithelial or early invasive cervical lesions and adverse pregnancy outcomes. METHODS: We conducted a population-based cohort study in which treatment data from the Cancer Registry of Norway were linked to the Medical Birth Registry of Norway to identify adverse pregnancy outcomes. All women (n=545,243) with singleton births (N=943,321) in Norway during 1998-2014 were included; 9,554 of births were in women treated before delivery...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27679120/comparison-of-clinical-outcomes-of-bovie-blade-versus-cold-knife-conization-as-a-treatment-modality-of-high-grade-cervical-intraepithelial-neoplasia
#10
J Hong, K A So, J W Kim
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27651725/optimal-cone-size-to-predict-positive-surgical-margins-after-cold-knife-conization-ckc-and-the-risk-factors-for-residual-disease
#11
Murat Öz, Nilüfer Çetinkaya, Elmas Korkmaz, Kerem Doğa Seçkin, Mehmet Mutlu Meydanlı, Tayfun Güngör
OBJECTIVE: To determine the optimal cone size to achieve a reliable sensitivity and specificity for clear surgical margins after cold knife conization (CKC). MATERIAL AND METHODS: The medical reports of patients who had high-grade cervical intraepithelial lesions, carcinoma in situ, or stage 1A1 microinvasive carcinoma in their CKC specimens between June 2008 and January 2015 were reviewed retrospectively. RESULTS: In total, 315 women fulfilled the inclusion criteria...
2016: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/27418835/meta-analysis-of-cold-knife-conization-versus-loop-electrosurgical-excision-procedure-for-cervical-intraepithelial-neoplasia
#12
Yan-Ming Jiang, Chang-Xian Chen, Li Li
OBJECTIVE: This meta-analysis aimed to compare the superiority of loop electrosurgical excision procedure (LEEP) or large loop excision of the transformation zone (LLETZ) versus cold-knife conization (CKC) in the surgical treatment of cervical intraepithelial neoplasia (CIN). METHODS: Systematic searches were performed in the MEDLINE, EMBASE, Cochrane databases, and the China National Knowledge Infrastructure Databases to identify all potential articles involving patients with CIN treated with LEEP/LLETZ or CKC published up to February 2016...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27356480/-a-retrospective-study-on-the-outcomes-of-the-oncology-fertility-and-pregnancy-in-patients-with-early-stage-cervical-cancer-after-undergoing-the-fertility-sparing-treatments
#13
COMPARATIVE STUDY
Y X Sun, Q Liu, K J Liu, P Q Li, Z J Hu
OBJECTIVE: To explore the outcomes of the oncology, the fertility and pregnancy on patients with early-stage cervical cancer after undergoing fertility-sparing treatments, and to investigate its value on clinical treatment. METHODS: A total of 29 patients with cervical cancer (stage Ⅰa2-Ⅰb1) who had undergone the fertility- sparing treatments in Renji Hospital, School of Medicine, Shanghai Jiaotong University from February 2010 to September 2015 were analyzed retrospectively...
June 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27008241/procedures-of-cervical-conization-a-national-survey-among-italian-colposcopy-units
#14
Francesco Sopracordevole, Jacopo DI Giuseppe, Francesca Mancioli, Giovanni DE Piero, Monica Buttignol, Andrea Ciavattini
BACKGROUND: The recent evolution of surgical techniques, anesthesia and treatment strategies has led to a decrease in the number of cervical conization procedures performed in ordinary hospitalization or with anesthetics other than local infiltration anesthesia of the cervix. Conization should be as least invasive as possible, favor women's compliance and resumption of normal daily activities after surgery. We evaluated various aspects of patient care revolving around conization (technical, healthcare, and administrative aspects) in the clinical practice of 26 Italian colposcopy units...
April 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/26894378/predictive-factors-for-residual-disease-in-hysterectomy-specimens-after-conization-in-early-stage-cervical-cancer
#15
A S M Wong, W H Li, T H Cheung
OBJECTIVE: To identify predictive factors for residual disease in hysterectomy specimens after a loop electrical excision procedure (LEEP) or cold knife conization in early-stage cervical cancer. STUDY DESIGN: A retrospective review was undertaken of the clinical records and pathology reports of 108 consecutive patients who were diagnosed with early invasive cervical cancer stage IA1 to IB1 by cold knife conization or LEEP, and underwent subsequent hysterectomy or radical hysterectomy at the Gynae-oncology Unit, Queen Elizabeth Hospital between 2000 and 2012...
April 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26868062/world-health-organization-guidelines-for-treatment-of-cervical-intraepithelial-neoplasia-2-3-and-screen-and-treat-strategies-to-prevent-cervical-cancer
#16
Nancy Santesso, Reem A Mustafa, Holger J Schünemann, Marc Arbyn, Paul D Blumenthal, Joanna Cain, Michael Chirenje, Lynette Denny, Hugo De Vuyst, Linda O'Neal Eckert, Sara E Forhan, Eduardo L Franco, Julia C Gage, Francisco Garcia, Rolando Herrero, José Jeronimo, Enriquito R Lu, Silvana Luciani, Swee Chong Quek, Rengaswamy Sankaranarayanan, Vivien Tsu, Nathalie Broutet
BACKGROUND: It is estimated that 1%-2% of women develop cervical intraepithelial neoplasia grade 2-3 (CIN 2-3) annually worldwide. The prevalence among women living with HIV is higher, at 10%. If left untreated, CIN 2-3 can progress to cervical cancer. WHO has previously published guidelines for strategies to screen and treat precancerous cervical lesions and for treatment of histologically confirmed CIN 2-3. METHODS: Guidelines were developed using the WHO Handbook for Guideline Development and the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach...
March 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/26863789/-colposcopy-assisted-laser-microsurgery-for-cervical-pathology
#17
I Karagyozov
AIM: A short presentation of the method--laser microsurgery and analysis of the achieved results. MATERIALS AND METHODS: 631 laser procedures were done for 3 years (2008- 2011) at Tokuda hospital outpatient department. These procedures were divided as follows: 607 laser vaporizations and 24 laser conisations. Indications for vaporizations were: CINI-114 patients, CIN II--26 patients, CIN III (without invasion of the cervical os) -26 patients and 422 patients were done laser vaporization for different reasons-papiloma, leucoplakia, atypical vessels and so on...
2015: Akusherstvo i Ginekologii︠a︡
https://www.readbyqxmd.com/read/26643302/systematic-reviews-and-meta-analyses-of-benefits-and-harms-of-cryotherapy-leep-and-cold-knife-conization-to-treat-cervical-intraepithelial-neoplasia
#18
REVIEW
Nancy Santesso, Reem A Mustafa, Wojtek Wiercioch, Rohan Kehar, Shreyas Gandhi, Yaolong Chen, Adrienne Cheung, Jessica Hopkins, Rasha Khatib, Bin Ma, Ahmad A Mustafa, Nancy Lloyd, Darong Wu, Nathalie Broutet, Holger J Schünemann
BACKGROUND: Cervical intraepithelial neoplasia (CIN) stage 2-3 is a premalignant lesion that can progress to cervical cancer in 10-20 years if untreated. OBJECTIVES: To conduct systematic reviews of randomized and nonrandomized studies for effects of cryotherapy, loop electrosurgical excision procedure (LEEP), and cold knife conization (CKC) as treatment for CIN 2-3. SEARCH STRATEGY: Medline, Embase, and other databases were searched to February 2012 for benefits, and to July 2012 for harms...
March 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/26461233/multiple-papillomavirus-infection-and-size-of-colposcopic-lesions-among-women-with-cervical-intraepithelial-neoplasia
#19
Arsenio Spinillo, Barbara Gardella, Anna Daniela Iacobone, Stefania Cesari, Paola Alberizzi, Enrico Maria Silini
OBJECTIVE: The aim of the study was to evaluate the association between the size of cervical lesions as detected by colposcopy and multiple human papillomavirus (HPV) infection in subjects with cervical intraepithelial neoplasia (CIN). METHODS: A case series of 898 subjects with CIN diagnosed by histopathology and infected by high-risk HPV. Human papillomavirus genotypes were identified using the INNO-LIPA genotyping system. RESULTS: The rates of CIN 1, CIN 2, and CIN 3+ lesions were 53...
January 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/26418271/an-analysis-of-the-outcomes-of-cervical-cone-biopsies-performed-in-a-low-resource-setting
#20
COMPARATIVE STUDY
C A Okonkwo, D O Selo-Ojeme
Following skills transfer to this low resource setting, we carried out a descriptive analysis of the outcomes of all cone biopsies performed for women with cervical intra-epithelial neoplasia 3 (CIN 3). We also compared two methods of cone biopsy. All the women had follow-up smear tests at 6 and 18 months. There were no cases of CIN 3 at follow-up. 80% had normal smears at 18 months and 20% had CIN 1. Compared with knife cone biopsy, women who had an electric knife (hand-held diathermy blade) cone biopsy had a significantly smaller volume of mean blood loss (55...
2015: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
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