keyword
https://read.qxmd.com/read/38528653/contrast-free-endovascular-aneurysm-repair-combined-with-fibrin-sealant-filling-for-treating-abdominal-aortic-aneurysm-technical-note
#1
JOURNAL ARTICLE
Longtu Zhu, Wenying Guo, Li Chen, Hao Zhang, Bing Xu, Zhichen Ding, Qingsheng Lu, Lei Zhang
INTRODUCTION: Endovascular aneurysm repair using iodinated contrast agents risks contrast-induced nephropathy, especially in high-risk patients. This technical note describes a contrast-free endovascular aneurysm repair (EVAR) protocol using preoperative imaging measurement and fibrin sealant (FS) filling. TECHNIQUE: Preoperative imaging measurement and intraoperative guidewire manipulation facilitated anatomical identification without contrast. After endograft deployment, the aneurysm sac was filled with FS if endoleak was indicated by pressure fluctuations...
March 25, 2024: Journal of Endovascular Therapy
https://read.qxmd.com/read/38526065/the-effect-of-the-concurrent-use-of-dexmedetomidine-dex-during-the-perioperative-period-on-the-renal-function-of-patients-following-craniocerebral-interventional-surgery
#2
JOURNAL ARTICLE
Lu Qian, Nianqiang Hu, Yijin Yu
BACKGROUND: Craniocerebral interventional surgery is a common and essential treatment for cerebrovascular diseases. Despite continuous progress in interventional diagnosis and treatment technology, there is no effective method to alleviate contrast-induced kidney injuries. In this retrospective cohort study, we investigated the effect of the concurrent use of Dexmedetomidine (DEX) during the perioperative period on the renal function of patients following craniocerebral interventional surgery...
March 25, 2024: International Journal of Neuroscience
https://read.qxmd.com/read/38524741/does-metabolic-syndrome-increase-contrast-induced-nephropathy-in-patients-with-normal-renal-function
#3
JOURNAL ARTICLE
Hasan Shemirani, Ali Hosseini
BACKGROUND: Contrast-induced nephropathy (CIN) is associated with increased mortality and morbidity in patients undergoing coronary angiography (CAG) and percutaneous coronary intervention. This study aimed to compare the incidence of CIN in two groups of patients with and without metabolic syndrome (Mets) with baseline normal renal function. MATERIALS AND METHODS: In this case - control study, 260 patient candidates for CAG, 130 patients with Mets and 130 patients without Mets participated, and their serum creatinine (Cr) level before and the 48 and 72 h after the angiography was measured...
2024: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://read.qxmd.com/read/38513060/inorganic-nitrate-benefits-contrast-induced-nephropathy-after-coronary-angiography-for-acute-coronary-syndromes-the-nitrate-cin-trial
#4
JOURNAL ARTICLE
Daniel A Jones, Anne-Marie Beirne, Matthew Kelham, Lucinda Wynne, Mervyn Andiapen, Krishnaraj S Rathod, Tipparat Parakaw, Jessica Adams, Annastazia Learoyd, Kamran Khan, Thomas Godec, Paul Wright, Sotiris Antoniou, Andrew Wragg, Muhammad Yaqoob, Anthony Mathur, Amrita Ahluwalia
BACKGROUND AND AIMS: Contrast-induced nephropathy (CIN), also known as contrast-associated acute kidney injury (CA-AKI) underlies a significant proportion of the morbidity and mortality following coronary angiographic procedures in high-risk patients and remains a significant unmet need. In pre-clinical studies inorganic nitrate, which is chemically reduced in vivo to nitric oxide, is renoprotective but this observation is yet to be translated clinically. In this study, the efficacy of inorganic nitrate in the prevention of CIN in high-risk patients presenting with acute coronary syndromes (ACS) is reported...
March 21, 2024: European Heart Journal
https://read.qxmd.com/read/38510924/underutilization-of-left-heart-catheterization-in-kidney-transplant-patients-presenting-with-non-st-segment-elevation-myocardial-infarction
#5
JOURNAL ARTICLE
Ahmad Mustafa, Samer Asmar, Chapman Wei, John Afif, Shahkar Khan, Taqi Rizvi, Radu Grovu, Mitchell Weinberg, Suzanne El-Sayegh
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of mortality in kidney transplant (KT) patients. The perceived risk of contrast-induced nephropathy (CIN) may create a reluctance to perform coronary angiography in patients presenting with non-ST segment elevation myocardial infarction (NSTEMI). METHODS: National Inpatient Sample (NIS) Database was used to sample individuals presenting with NSTEMI. Patients were stratified into KT and Non-KT cohorts...
June 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38488664/prognostic-role-of-neutrophil-to-lymphocyte-ratio-in-contrast-induced-nephropathy-a-systematic-review-and-meta-analysis
#6
REVIEW
Tao He, Behnood Mohammadpour, Matthew Willman, Shirin Yaghoobpoor, Jonathan Willman, Brandon Lucke-Wold, Sarina Aminizadeh, Shokoufeh Khanzadeh, Aida Bazrgar, Arshin Ghaedi
This meta-analysis assessed the use of the neutrophil-to-lymphocyte ratio (NLR) as a means of early detection of contrast-induced nephropathy (CIN) following diagnostic or therapeutic procedures. We used Web of Science, PubMed, and Scopus to conduct a systematic search. There was no limitation regarding language or date of publication. We reported standardized mean difference (SMD) with a 95% confidence interval (CI). Due to high heterogeneity, a random-effects model was used, and the Newcastle-Ottawa scale was used for quality assessment...
March 15, 2024: Angiology
https://read.qxmd.com/read/38476886/programmed-cell-death-4-blocks-autophagy-and-promotes-dopaminergic-neuronal-injury-in-parkinson-s-disease
#7
JOURNAL ARTICLE
Guiling Cao, Tao Kang, Nini Li, Peng Li
Dysregulation of autophagy has previously been associated with the formation of toxic proteins, such as α-synuclein, in patients with Parkinson's disease (PD). In addition, it has been indicated that programmed cell death 4 (PDCD4) can inhibit autophagy in certain conditions, such as diabetic nephropathy, atherosclerosis and cardiac hypertrophy. Therefore, the hypothesis that PDCD4 can promote dopaminergic neuron damage through autophagy was proposed. To explore this hypothesis, the present study treated human neuroblastoma SK-N-SH cells with 1-methyl-4-phenylpyridinium (MPP+ ) to establish an in vitro model of PD...
April 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38467037/n-acetylcysteine-to-reduce-mortality-for-patients-requiring-cardiac-catheterization-or-cardiac-surgery-a-systematic-review-and-meta-analysis
#8
JOURNAL ARTICLE
Clement Gakuba, Alexandru-Daniel Dumitrascu, Pierre-Emmanuel Marson, Damien Legallois, Jean-Luc Hanouz, Denis Vivien, Sara Martinez De Lizarrondo, Maxime Gauberti, Damiano Cerasuolo
Multimers of von Willebrand factor (VWF) play a critical role in various processes inducing morbidity and mortality in cardiovascular risk patients. With the ability to reduce VWF multimers, N-acetylcysteine (NAC) could reduce mortality in patients undergoing coronary catheterization or cardiac surgery. However, its impact in perioperative period has never been studied so far in regard of its potential cardiovascular benefits. Then, four databases were searched for randomized controlled trials that compared in-hospital mortality between an experimental group, with NAC, and a control group without NAC, in patients undergoing coronary catheterization or cardiac surgery...
March 6, 2024: Journal of Cardiovascular Pharmacology
https://read.qxmd.com/read/38462389/the-effect-of-ctca-guided-selective-invasive-graft-assessment-on-coronary-angiographic-parameters-and-outcomes-insights-from-the-bypass-ctca-trial
#9
JOURNAL ARTICLE
Matthew Kelham, Anne-Marie Beirne, Krishnaraj S Rathod, Mervyn Andiapen, Lucinda Wynne, Rohini Ramaseshan, Annastazia E Learoyd, Nasim Forooghi, James C Moon, Ceri Davies, Christos V Bourantas, Andreas Baumbach, Charlotte Manisty, Andrew Wragg, Amrita Ahluwalia, Francesca Pugliese, Anthony Mathur, Daniel A Jones
BACKGROUND: Computed tomography cardiac angiography (CTCA) is recommended for the evaluation of patients with prior coronary artery bypass graft (CABG) surgery. The BYPASS-CTCA study demonstrated that CTCA prior to invasive coronary angiography (ICA) in CABG patients leads to significant reductions in procedure time and contrast-induced nephropathy (CIN), alongside improved patient satisfaction. However, whether CTCA information was used to facilitate selective graft cannulation at ICA was not protocol mandated...
March 9, 2024: Journal of Cardiovascular Computed Tomography
https://read.qxmd.com/read/38443965/amelioration-of-diabetic-nephropathy-in-mice-by-a-single-intravenous-injection-of-human-mesenchymal-stromal-cells-at-early-and-later-disease-stages-is-associated-with-restoration-of-autophagy
#10
JOURNAL ARTICLE
Jingjing He, Boxin Liu, Xiaofeng Du, Yan Wei, Desheng Kong, Baofeng Feng, Ruiyun Guo, Ernest Amponsah Asiamah, Matthew D Griffin, Sean O Hynes, Sanbing Shen, Yan Liu, Huixian Cui, Jun Ma, Timothy O'Brien
BACKGROUND AND AIMS: Mesenchymal stromal cells (MSCs) a potentially effective disease-modulating therapy for diabetic nephropathy (DN) but their clinical translation has been hampered by incomplete understanding of the optimal timing of administration and in vivo mechanisms of action. This study aimed to elucidate the reno-protective potency and associated mechanisms of single intravenous injections of human umbilical cord-derived MSCs (hUC-MSCs) following shorter and longer durations of diabetes...
March 5, 2024: Stem Cell Research & Therapy
https://read.qxmd.com/read/38440007/evaluating-the-differential-risk-of-contrast-induced-nephropathy-among-diabetic-and-non-diabetic-patients-following-percutaneous-coronary-intervention
#11
JOURNAL ARTICLE
Fahad R Khan, Tariq Nawaz, Wasim Sajjad, Sadam Hussain, Muhammad Amin, Hassan Ali
Background Contrast-induced nephropathy (CIN) significantly complicates percutaneous coronary intervention (PCI), with a higher prevalence in diabetic patients. This study compares the incidence of CIN in diabetic and non-diabetic patients undergoing PCI. Material and methods Conducted at Lady Reading Hospital, Peshawar, PAK, from January to December 2023, this observational study involved 450 adult patients with coronary artery disease (CAD) undergoing PCI. The cohort was categorized based on diabetes status, excluding patients with chronic kidney disease and those on renal replacement therapy...
February 2024: Curēus
https://read.qxmd.com/read/38411168/efficacy-of-nicorandil-and-ranolazine-in-prevention-of-contrast-induced-nephropathy-in-patients-with-mild-to-moderate-renal-dysfunction-a-randomized-controlled-trial
#12
JOURNAL ARTICLE
Jamal Yusuf, Gyan Prakash, Safal Safal, Vimal Mehta, Saibal Mukhopadhyay
INTRODUCTION: Contrast-induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI). There is conflicting evidence regarding efficacy of nicorandil in CIN prevention. With respect to ranolazine, there is physiological possibility as well as data in animal study regarding its protective effect against CIN; there is, however, no human data till date. AIM AND OBJECTIVES: To assess the efficacy of nicorandil and ranolazine in preventing CIN...
February 20, 2024: Coronary Artery Disease
https://read.qxmd.com/read/38404852/prevalence-of-contrast-induced-nephropathy-after-primary-percutaneous-coronary-intervention-at-a-tertiary-referral-hospital
#13
JOURNAL ARTICLE
Zahra Masoomi, Ali Mohammad Nasirian, Mansoor Namazi, Moein Zangiabadian, Abdoreza Dayani, Mohammad Shahidi, Hossein Saghafi, Amir Ghaffari Jolfayi
OBJECTIVE: This study aimed to quantify the incidence of Contrast-induced nephropathy (CIN) in patients undergoing primary percutaneous coronary intervention (PPCI) due to acute ST-elevation myocardial infarction (STEMI). METHODS: From April 2019 to March 2022, a prospective, observational study enrolled 213 consecutive STEMI patients referred to a tertiary hospital for PPCI. Participants were divided into tow groups based on the presence or absence of contrast-induced nephropathy...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38385425/kidney-transplant-recipient-with-cerebral-paradoxical-embolism-following-recurrent-idiopathic-deep-vein-thrombosis-and-pulmonary-embolism-case-report-and-review-of-the-literature
#14
REVIEW
Osama Gheith, Hassanen Abo Atya, Ayman Maher Nagib, Ahmed Sami, Prasad Nair, Medhat Alawady, Khaja M Sharfuddin, Ahmed Fathy, Wesam Mattar, Ahmed Abass, Abdulwahab Mahmoud, Mohamed Al Ajmi, Torki Al Otaibi
Paradoxical embolism occurs when a thrombus crosses an intracardiac defect into the systemic circulation. Here, we present the case of a 35-yearold male kidney transplant recipient with a cerebral paradoxical embolism associated with a spontaneous venous thromboembolism. This patient had recurrent deep venous thrombosis and showering emboli to the lung and paradoxically to the brain through patent foramen ovale, and we treated him successfully. The role of bubble echocardiography was essential in diagnosis to avoid contrast-induced nephropathy...
January 2024: Experimental and Clinical Transplantation
https://read.qxmd.com/read/38357976/tetramethylpyrazine-attenuates-renal-tubular-epithelial-cell-ferroptosis-in-contrast-induced-nephropathy-by-inhibiting-transferrin-receptor-and-intracellular-reactive-oxygen-species
#15
JOURNAL ARTICLE
Zhongqiang Zhu, Jun Li, Zhiyong Zhi Song, Tonglu Tong Li, Zongping Zong Li, Xuezhong Gong
Contrast-induced nephropathy (CIN) is a leading cause of hospital-acquired acute kidney injury (AKI). Recently ferroptosis was reported to be crucial for AKI pathogenesis. Our previous studies indicated antioxidant tetramethylpyrazine (TMP) prevent CIN in vivo. However, whether ferroptosis is involved in TMP nephroprotective mechanism against CIN is unclear. In present study we investigated the role of renal tubular epithelial cell ferroptosis in TMP reno-protective effect against CIN and the molecular mechanisms by which TMP regulates ferroptosis...
February 14, 2024: Clinical Science (1979-)
https://read.qxmd.com/read/38357177/values-of-serum-neutrophil-gelatinase-associated-lipocalin-and-cystatin-c-after-percutaneous-coronary-intervention-for-early-diagnosis-of-contrast-induced-nephropathy
#16
JOURNAL ARTICLE
Ping Luo, Wei Ao, Dikai Xiang, Jian Wang, Jia Liu
OBJECTIVE: Serum creatinine (SCr) is not a sensitive and reliable index for the early diagnosis of acute kidney injury caused by contrast-induced nephropathy (CIN). The aim of this study was to explore the values of serum neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (Cys-C) after percutaneous coronary intervention (PCI) for the early diagnosis of CIN. METHODS: Three hundred patients receiving PCI from January 2018 to December 2020 were assigned to a CIN group (n=25) and a non-CIN group (n=275), respectively...
September 2023: African Health Sciences
https://read.qxmd.com/read/38349134/the-association-and-utility-of-left-ventricular-end-diastolic-pressure-in-predicting-the-development-of-and-in-managing-contrast-induced-nephropathy-in-patients-undergoing-coronary-angiography
#17
JOURNAL ARTICLE
Gaspar Del Rio-Pertuz, Natnicha Leelaviwat, Poemlarp Mekraksakit, Juthipong Benjanuwattra, Kenneth Nugent
Contrast-induced nephropathy (CIN) is a significant complication in patients undergoing coronary angiography, and its development is associated with increased morbidity and mortality. Left ventricular end-diastolic pressure (LVEDP) provides one index of left heart filling status. An elevated LVEDP can reflect volume overload or abnormal diastolic function and indicates a cardiac disorder. Data on the association between an elevated LVEDP and CIN are limited and have had conflicting results. We systematically searched the databases PubMed, Embase, and Scopus for full-text articles from database inception to May 2022...
February 13, 2024: Cardiology in Review
https://read.qxmd.com/read/38322630/the-treatment-of-coronary-artery-disease-in-patients-with-chronic-kidney-disease-gaps-challenges-and-solutions
#18
REVIEW
Ilya Losin, Keren-Cohen Hagai, David Pereg
BACKGROUND: Chronic kidney disease (CKD) is associated with a high burden of coronary artery disease (CAD), which remains the leading cause of death in CKD patients. Despite the high cardiovascular risk, ACS patients with renal dysfunction are less commonly treated with guideline-based medical therapy and are less frequently referred for coronary revascularization. SUMMARY: The management of CAD is more challenging in patients with CKD than in the general population due to concerns regarding side effects and renal toxicity, as well as uncertainty regarding clinical benefit of guideline-based medical therapy and interventions...
February 2024: Kidney Diseases
https://read.qxmd.com/read/38318774/the-roles-of-autophagy-in-the-treatment-of-diabetic-nephropathy-with-rapamycin
#19
JOURNAL ARTICLE
Ya Fu, Liang Zhang, Shupei Qin, Meng Tang, Yanxia Hao, Xuedong Chen, Yan Wang, Ting Zhou, Yuemei Xue, Long Cheng, Na Liu, Qifeng Jia, Yangyang Chen, Li Li
BACKGROUND: Rapamycin is known to induce autophagy, promote cell survival and inhibit the progression of diabetic nephropathy (DN). OBJECTIVES: The aim of this study was to examine the role of autophagy in the treatment of DN with rapamycin to provide the basis for the DN treatment with rapamycin. MATERIAL AND METHODS: Human mesangial cells (HMC) were cultured in a constant temperature incubator with 5% CO2, at 37°C and saturated humidity...
February 6, 2024: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://read.qxmd.com/read/38304292/fenestrated-endovascular-aortic-repair-of-a-superior-mesenteric-artery-aneurysm-using-carbon-dioxide-angiography-and-intravascular-ultrasound
#20
Darren Van Essen, Sarah M Taylor, Lavraj Lidher, Jeffrey G Grab, Henry Walton, Jeffery A Clark
Superior mesenteric artery aneurysms are rare; however, current guidelines suggest they all require repair due to the high rupture and mortality rates, and endovascular repair is an effective management strategy. Iodinated contrast traditionally used in endovascular repair can cause significant complications, including severe allergic reactions and contrast-induced nephropathy in patients with chronic renal disease. Therefore, other imaging methods should be used during endovascular procedures to reduce these risks...
April 2024: Journal of Vascular Surgery Cases and Innovative Techniques
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