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Exercise and Parkinson disease

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https://www.readbyqxmd.com/read/27922660/combined-vision-and-wearable-sensors-based-system-for-movement-analysis-in-rehabilitation
#1
Sofija Spasojević, Tihomir V Ilić, Slađan Milanović, Veljko Potkonjak, Aleksandar Rodić, José Santos-Victor
BACKGROUND: Traditional rehabilitation sessions are often a slow, tedious, disempowering and non-motivational process, supported by clinical assessment tools, i.e. evaluation scales that are prone to subjective rating and imprecise interpretation of patient's performance. Poor patient motivation and insufficient accuracy are thus critical factors that can be improved by new sensing / processing technologies. OBJECTIVES: We aim to develop a portable and affordable system, suitable for home rehabilitation, which combines vision-based and wearable sensors...
December 6, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27912936/effects-of-mind-body-exercises-on-the-physiological-and-psychosocial-well-being-of-individuals-with-parkinson-s-disease-a-systematic-review-and-meta-analysis
#2
REVIEW
JoJo Yan Yan Kwok, Kai Chow Choi, Helen Yue Lai Chan
OBJECTIVES: The effects of mind-body exercises on individuals with chronic illnesses have attracted increasing attention. However, little effort had been made to systematically review the effects of these mind-body exercises on individuals with Parkinson's disease (PD). This review aimed to appraise the current evidence of the effects of mind-body exercises on the physiological and psychological outcomes for the PD population. DESIGN: Systematic review and meta-analysis of randomized controlled trials...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27909646/the-neural-mechanisms-of-meditative-practices-novel-approaches-for-healthy-aging
#3
REVIEW
Bianca P Acevedo, Sarah Pospos, Helen Lavretsky
OBJECTIVES: Meditation has been shown to have physical, cognitive, and psychological health benefits that can be used to promote healthy aging. However, the common and specific mechanisms of response remain elusive due to the diverse nature of mind-body practices. METHODS: In this review, we aim to compare the neural circuits implicated in focused-attention meditative practices that focus on present-moment awareness to those involved in active-type meditative practices (e...
2016: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/27908782/adaptive-responses-of-neuronal-mitochondria-to-bioenergetic-challenges-roles-in-neuroplasticity-and-disease-resistance
#4
REVIEW
Sophia M Raefsky, Mark P Mattson
An important concept in neurobiology is "neurons that fire together, wire together" which means that the formation and maintenance of synapses is promoted by activation of those synapses. Very similar to the effects of the stress of exercise on muscle cells, emerging findings suggest that neurons respond to activity by activating signaling pathways (e.g., Ca(2+), CREB, PGC-1α, NF-κB) that stimulate mitochondrial biogenesis and cellular stress resistance. These pathways are also activated by aerobic exercise and food deprivation, two bioenergetic challenges of fundamental importance in the evolution of the brains of all mammals, including humans...
November 29, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/27893480/high-speed-resistance-training-modifies-load-velocity-and-load-power-relationships-in-parkinson-s-disease
#5
Meng Ni, Joseph F Signorile
Muscle power is a major neuromuscular factor affecting motor function and independence in patients with Parkinson's disease; and it is commonly targeted using high-speed exercise. This study examined the changes in velocities (Vpp) and percent loads (%1RMpp) at peak power, as well as load-velocity (L-V) and load-power (L-P) relationships, resulting from resistance training due to exercise choice and loading in older Parkinson's patients. Fourteen older adults with mild to moderate Parkinson's disease participated in a 12-week randomized controlled power training trial...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27891159/effects-of-health-qigong-exercises-on-relieving-symptoms-of-parkinson-s-disease
#6
Xiao Lei Liu, Shihui Chen, Yongtai Wang
The purpose of this study was to investigate the effects of Health Qigong on the treatment and releasing symptoms of Parkinson's disease (PD). Fifty-four moderate PD patients (N = 54) were randomly divided into experimental and control groups. Twenty-eight PD patients were placed in the experimental group in which the prescribed medication plus Health Qigong exercise will be used as intervention. The other 26 PD patients as the control group were treated only with regular medication. Ten-week intervention had been conducted for the study, and participants completed the scheduled exercises 5 times per week for 60 minutes each time (10 minutes for warm-up, 40 minutes for the exercise, and 10 minutes for cooldown)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27879959/balance-versus-resistance-training-on-postural-control-in-patients-with-parkinson-s-disease-a-randomised-controlled-trial
#7
Suhaila M Santos, Rubens A Da Silva, Marcelle B Terra, Isabela A Almeida, Lucio B De Melo, Henrique B Ferraz
BACKGROUND: Evidences have shown that physiotherapy programs may improve the balance of individuals with Parkinson's disease (PD); although it is not clear which specific exercise program is better. AIM: Compare the effectiveness of balance versus resistance training on postural control measures in PD patients. DESIGN: Randomised controlled trial. SETTING: The study was conducted in a physiotherapy outpatient clinic of a university hospital...
November 23, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27858719/regular-exercise-quality-of-life-and-mobility-in-parkinson-s-disease-a%C3%A2-longitudinal-analysis-of-national-parkinson-foundation-quality-improvement-initiative-data
#8
Miriam R Rafferty, Peter N Schmidt, Sheng T Luo, Kan Li, Connie Marras, Thomas L Davis, Mark Guttman, Fernando Cubillos, Tanya Simuni
BACKGROUND: Research-based exercise interventions improve health-related quality of life (HRQL) and mobility in people with Parkinson's disease (PD). OBJECTIVE: To examine whether exercise habits were associated with changes in HRQL and mobility over two years. METHODS: We identified a cohort of National Parkinson Foundation Quality Improvement Initiative (NPF-QII) participants with three visits. HRQL and mobility were measured with the Parkinson's Disease Questionnaire (PDQ-39) and Timed Up and Go (TUG)...
November 14, 2016: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/27852513/premorbid-exercise-engagement-and-motor-reserve-in-parkinson-s-disease
#9
Mun K Sunwoo, Ji E Lee, Jin Y Hong, Byung S Ye, Hye S Lee, Jungsu S Oh, Jae S Kim, Phil H Lee, Young H Sohn
BACKGROUND: Life-long experiences of cognitive activity could enhance cognitive reserve, which may lead individuals to show less cognitive deficits in Alzheimer's disease, despite similar pathological changes. We performed this study to test whether premorbid physical activity may enhance motor reserve in Parkinson's disease (PD) (i.e., less motor deficits despite similar degrees of dopamine depletion). METHODS: We assessed engagement in premorbid leisure-time exercise among 102 drug naive PD patients who had been initially diagnosed at our hospital by dopamine transporter scanning...
November 1, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/27851668/instability-resistance-training-improves-neuromuscular-outcome-in-parkinson-s-disease
#10
Carla Silva-Batista, Daniel Montie Corcos, Renato Barroso, Fabian J David, Hélcio Kanegusuku, Cláudia Forjaz, Marco Túlio de Mello, Hamilton Roschel, Valmor Tricoli, Carlos Ugrinowitsch
PURPOSE: This study compared the effects of resistance training (RT) and resistance training with instability (RTI) on neuromuscular and total training volume (TTV) outcomes obtained as part of the Instability Resistance Training Trial in Parkinson's disease (IRRT-PD). It also used a linear multiple regression (forward stepwise method) to identify the contribution of neuromuscular outcomes to previously published improvements in the timed-up-and-go-test and the Unified Parkinson's Disease Rating Scale, motor subscale score (UPDRS-III)...
November 16, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27845808/use-of-complementary-health-approaches-in-individuals-with-parkinson-s-disease
#11
Ju Young Shin, Ryan T Pohlig, Barbara Habermann
Parkinson's disease (PD) is neurodegenerative and requires ongoing therapy. The purpose of the current study was two-fold: to (a) describe the prevalence, types, and associated factors of complementary health approaches (CHA) used in individuals with PD; and (b) explore reasons for CHA use. A self-administered, cross-sectional survey was used. The response rate was 61.9% (N = 135), and 74.1% of participants used CHA for either PD or general health. The most widely used CHA included exercise, yoga, massage, vitamins, coenzyme Q10, and coconut oil...
November 15, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27837101/phase-ii-randomised-controlled-trial-of-a-6-month-self-managed-community-exercise-programme-for-people-with-parkinson-s-disease
#12
Johnny Collett, Marloes Franssen, Andy Meaney, Derick Wade, Hooshang Izadi, Martin Tims, Charlotte Winward, Marko Bogdanovic, Andrew Farmer, Helen Dawes
BACKGROUND: Evidence for longer term exercise delivery for people with Parkinson's disease (PwP) is deficient. AIM: Evaluate safety and adherence to a minimally supported community exercise intervention and estimate effect sizes (ES). METHODS: 2-arm parallel phase II randomised controlled trial with blind assessment. PwP able to walk ≥100 m and with no contraindication to exercise were recruited from the Thames valley, UK, and randomised (1:1) to intervention (exercise) or control (handwriting) groups, via a concealed computer-generated list...
November 11, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27834670/resistance-training-with-instability-is-more-effective-than-resistance-training-in-improving-spinal-inhibitory-mechanisms-in-parkinson-s-disease
#13
Carla Silva-Batista, Eugenia Casella Tavares Mattos, Daniel M Corcos, Jessica M Wilson, Charles J Heckman, Helcio Kanegusuku, Maria Elisa Pimentel Piemonte, Marco Túlio de Mello, Claudia Lucia de Moraes Forjaz, Hamilton Roschel, Valmor Alberto Tricoli, Carlos Ugrinowitsch
BACKGROUND: This study assessed: 1) the effects of 12 weeks of resistance training (RT) and resistance training with instability (RTI) on presynaptic inhibition (PSI) and disynaptic reciprocal inhibition (DRI) of patients with Parkinson's disease (PD); 2) the effectiveness of RT and RTI in moving PSI and DRI values of patients towards values of age-matched healthy controls (HC [Z-score analysis]); and 3) associations between PSI and DRI changes and clinical outcomes changes previously published...
November 10, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27822467/a-kinect-based-physiotherapy-and-assessment-platform-for-parkinson-s-disease-patients
#14
Ioannis Pachoulakis, Nikolaos Xilourgos, Nikolaos Papadopoulos, Anastasia Analyti
We report on a Kinect-based, augmented reality, real-time physiotherapy platform tailored to Parkinson's disease (PD) patients. The platform employs a Kinect sensor to extract real-time 3D skeletal data (joint information) from a patient facing the sensor (at 30 frames per second). In addition, a small collection of exercises practiced in traditional physiotherapy for PD patients has been implemented in the Unity 3D game engine. Each exercise employs linear or circular movement patterns and poses very light-weight processing demands on real-time computations...
2016: Journal of Medical Engineering
https://www.readbyqxmd.com/read/27816415/neuroprotective-effects-of-endurance-exercise-against-neuroinflammation-in-mptp-induced-parkinson-s-disease-mice
#15
Yongchul Jang, Jung-Hoon Koo, Insu Kwon, Eun-Bum Kang, Hyun-Seob Um, Hideaki Soya, Youngil Lee, Joon-Yong Cho
Parkinson's disease (PD) is one of the main degenerative neurological disorders accompanying death of dopaminergic neurons prevalent in aged population. Endurance exercise (EE) has been suggested to confer neurogenesis and mitigate the degree of seriousness of PD. However, underlying molecular mechanisms responsible for exercise-mediated neuroprotection against PD remain largely unknown. Given the relevant interplay between elevated α-synuclein and neuroinflammation in a poor prognosis and vicious progression of PD and anti-inflammatory effects of EE, we hypothesized that EE would reverse motor dysfunction and cell death caused by PD...
November 2, 2016: Brain Research
https://www.readbyqxmd.com/read/27814622/interventions-in-parkinson-s-disease-role-of-executive-function
#16
Abhimanyu Mahajan, Jennifer A Deal, Michelle Carlson
The cortico-striatal network plays a major role in executive functions (EF), and is believed to play a role in the pathophysiology of Parkinson's disease (PD). However, the tools to assess EF are limited. This review assesses the impact of all PD interventions, namely, pharmacotherapy, physical exercise and Deep Brain Stimulation (DBS) surgery on EF. The effect of PD pharmacotherapy varies with the drug class, neuropsychological test used and the affected dopamine receptor family. There appears to be a benefit of aerobic exercise on EF, including judgment and attention...
January 1, 2017: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/27807532/effects-of-therapeutic-tai-chi-on-functional-fitness-and-activities-of-daily-living-in-patients-with-parkinson-disease
#17
Hye-Jung Choi
The purpose of the study is to investigate the effects of therapeutic Tai chi (TTC) on the functional fitness status and activities of daily living (ADL) of patients with Parkinson disease (PD). The participants were clinically stable PDs in Hoehn and Yahr stage 1-2. These patients were randomly assigned to either the TTC group (n=11) or the control (CON) group (n=9). The TTC exercised at the clinic 2 times a week and performed home-based activity 1 time per week for 12 weeks. All the PDs were evaluated for functional fitness test and ADL screen before and after the 12-week trial...
October 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/27790107/do-dopaminergic-impairments-underlie-physical-inactivity-in-people-with-obesity
#18
REVIEW
Alexxai V Kravitz, Timothy J O'Neal, Danielle M Friend
Obesity is associated with physical inactivity, which exacerbates the negative health consequences of obesity. Despite a wide consensus that people with obesity should exercise more, there are few effective methods for increasing physical activity in people with obesity. This lack is reflected in our limited understanding of the cellular and molecular causes of physical inactivity in obesity. We hypothesize that impairments in dopamine signaling contribute to physical inactivity in people with obesity, as in classic movement disorders such as Parkinson's disease...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27787472/resistance-training-improves-sleep-quality-in-subjects-with-moderate-parkinson-s-disease
#19
Carla Silva-Batista, Leandro Campos de Brito, Daniel M Corcos, Hamilton Roschel, Marco Túlio de Mello, Maria Elisa Pimentel Piemonte, Valmor Tricoli, Carlos Ugrinowitsch
The objectives of this study were to test if 12 weeks of progressive resistance training (RT) improves sleep quality and muscle strength in subjects with moderate Parkinson's disease (PD) and if sleep quality values of subjects with moderate PD are closer to those of age-matched healthy controls (HC) at post-training. This was a randomized controlled trial conducted between March 2013 and September 2014. Twenty-two subjects with moderate PD were randomly assigned to a non-exercising control group (n=11) or a RT group (n=11)...
October 13, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27782011/reviewing-the-evidence-in-pursuit-of-a-framework-for-parkinson-disease-rehabilitation-with-games
#20
Aslihan Tece Bayrak, Burkhard Wünsche, Christof Lutteroth
Exercise gaming has been receiving a significant interest from both consumers and researchers. Be it for the purposes of weight loss, physical fitness or even just enjoyment, the potential of games to support rehabilitation has also been under investigation for a while. Due to our aging society, game based therapies could be a solution for optimizing resources and reducing rehabilitation costs. This paper aims to discuss the potential capacity of games as systems to enhance the relation of physical exercise and cognition for the rehabilitation of Parkinson Disease...
2016: Studies in Health Technology and Informatics
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