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Exercise and Parkinson disease

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https://www.readbyqxmd.com/read/29916576/validity-and-reliability-of-textile-system-sensoria-for-posturographic-measurements
#1
Giovanni D'Addio, Luigi Iuppariello, Paolo Bifulco, Bernardo Lanzillo, Nicola Pappone, Mario Cesarelli
OBJECTIVES: Smart fabrics and interactive textiles are a relatively new area of research, with many potential applications in the field of biomedical engineering. The ability of smart textiles to interact with the body provides a novel means to sense the wearer's physiology and respond to the needs of the wearer. Physiological signals, such as heart rate, breathing rates, and activity levels, are useful indicators of health status. These signals can be measured by means of textile-based sensors integrated into smart clothing which has the ability to keep a digital record of the patient's physiological responses since his or her last clinical visit, allowing doctors to make a more accurate diagnosis...
December 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29915907/a-survey-of-application-of-complementary-and-alternative-medicine-in-chinese-patients-with-parkinson-s-disease-a-pilot-study
#2
Xue-Wei Pan, Xiao-Guang Zhang, Xia-Chan Chen, Qi Lu, Ying-Si Hu, Li-Ya Han, Jian-le Zheng, Jie Jin, Guo-Qing Zheng
OBJECTIVE: To investigate the prevalence and spectrum of complementary and alternative medicine (CAM) application and its related-factors in Parkinson's disease (PD) patients in China. METHODS: A structured questionnaire regarding the use of CAMs was administered to PD patients by face-to-face interview. Demographic and social variables, clinical characteristics and treatments, and the related factors of PD were also surveyed. RESULTS: Ninety out of 113 patients (79...
June 18, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29895328/glucocorticoid-dependent-redd1-expression-reduces-muscle-metabolism-to-enable-adaptation-under-energetic-stress
#3
Florian A Britto, Fabienne Cortade, Yassine Belloum, Marine Blaquière, Yann S Gallot, Aurélie Docquier, Allan F Pagano, Elodie Jublanc, Nadia Bendridi, Christelle Koechlin-Ramonatxo, Béatrice Chabi, Marc Francaux, François Casas, Damien Freyssenet, Jennifer Rieusset, Sophie Giorgetti-Peraldi, Gilles Carnac, Vincent Ollendorff, François B Favier
BACKGROUND: Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized as a negative regulator of muscle mass through inhibition of the Akt/mTORC1 signaling pathway. REDD1 expression is notably induced following glucocorticoid secretion, which is a component of energy stress responses. RESULTS: Unexpectedly, we show here that REDD1 instead limits muscle loss during energetic stresses such as hypoxia and fasting by reducing glycogen depletion and AMPK activation...
June 12, 2018: BMC Biology
https://www.readbyqxmd.com/read/29889088/improvement-in-upper-limb-updrs-motor-scores-following-fast-paced-arm-exercise-a-pilot-study
#4
Shelly Levy-Tzedek, Dan Arbelle, Dan Forman, Yair Zlotnik
BACKGROUND: The symptoms of patients with Parkinson's disease (PD) have been shown to improve when they perform fast-paced rhythmic cycling movements with their lower limbs. OBJECTIVE: Our goal in this pilot experiment was to test the feasibility and the benefits of a short exercise program involving fast-paced rhythmic movements of the upper limb for patients with PD. METHODS: We used an experimental procedure that elicits large, fast-paced movements by the participants without the direct instructions to do so by the experimenter...
June 6, 2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29886075/a-high-intensity-multi-component-agility-intervention-improves-parkinson-s-patients-clinical-and-motor-symptoms
#5
József Tollár, Ferenc Nagy, Norbert Kovács, Tibor Hortobágyi
OBJECTIVE: To determine the effects of a high-intensity exercise therapy using sensorimotor and visual stimuli on non-demented Parkinson's disease (PD) patients' clinical symptoms, mobility, and standing balance DESIGN: Randomized clinical intervention, using a before-after trial design. SETTING: University hospital setting. PARTICIPANTS: 72 PD patients with Hoehn-Yahr stage of 2 to 3, of whom 64 were randomized, and 55 completed the study...
June 7, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29885877/the-effects-of-mindfulness-meditation-based-complex-exercise-program-on-motor-and-non-motor-symptoms-and-quality-of-life-in-patients-with-parkinson-s-disease
#6
Hye Gyeong Son, Eun Ok Choi
No abstract text is available yet for this article.
June 7, 2018: Asian Nursing Research
https://www.readbyqxmd.com/read/29874566/hallmarks-of-brain-aging-adaptive-and-pathological-modification-by-metabolic-states
#7
REVIEW
Mark P Mattson, Thiruma V Arumugam
During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network activity, dysregulation of neuronal Ca2+ homeostasis, the accrual of oxidatively modified molecules and organelles, and inflammation. These alterations render the aging brain vulnerable to Alzheimer's and Parkinson's diseases and stroke. Emerging findings are revealing mechanisms by which sedentary overindulgent lifestyles accelerate brain aging, whereas lifestyles that include intermittent bioenergetic challenges (exercise, fasting, and intellectual challenges) foster healthy brain aging...
June 5, 2018: Cell Metabolism
https://www.readbyqxmd.com/read/29867337/commentary-an-interactive-videogame-for-arm-and-hand-exercise-in-people-with-parkinson-s-disease-a-randomized-controlled-trial
#8
COMMENT
Veeral Desai, Arnav Gupta, Michael Wong
No abstract text is available yet for this article.
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29849887/epigenetic-modifications-of-the-%C3%AE-synuclein-gene-and-relative-protein-content-are-affected-by-ageing-and-physical-exercise-in-blood-from-healthy-subjects
#9
Simona Daniele, Barbara Costa, Deborah Pietrobono, Chiara Giacomelli, Caterina Iofrida, Maria Letizia Trincavelli, Jonathan Fusi, Ferdinando Franzoni, Claudia Martini
Epigenetic regulation may contribute to the beneficial effects of physical activity against age-related neurodegeneration. For example, epigenetic alterations of the gene encoding for α -synuclein ( SNCA ) have been widely explored in both brain and peripheral tissues of Parkinson's disease samples. However, no data are currently available about the effects of physical exercise on SNCA epigenetic regulation in ageing healthy subjects. The present paper explored whether, in healthy individuals, age and physical activity are related to blood intron1- SNCA ( SNCAI1 ) methylation, as well as further parameters linked to such epigenetic modification (total, oligomeric α -synuclein and DNA methyltransferase concentrations in the blood)...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29796338/tai-chi-for-reducing-dual-task-gait-variability-a-potential-mediator-of-fall-risk-in-parkinson-s-disease-a-pilot-randomized-controlled-trial
#10
Gloria Vergara-Diaz, Kamila Osypiuk, Jeffrey M Hausdorff, Paolo Bonato, Brian J Gow, Jose Gv Miranda, Lewis R Sudarsky, Daniel Tarsy, Michael D Fox, Paula Gardiner, Cathi A Thomas, Eric A Macklin, Peter M Wayne
Objectives: To assess the feasibility and inform design features of a fully powered randomized controlled trial (RCT) evaluating the effects of Tai Chi (TC) in Parkinson's disease (PD) and to select outcomes most responsive to TC assessed during off-medication states. Design: Two-arm, wait-list controlled RCT. Settings: Tertiary care hospital. Subjects: Thirty-two subjects aged 40-75 diagnosed with idiopathic PD within 10 years...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29791244/the-need-for-mapping-personal-goals-to-exercise-dosage-in-community-based-exercise-programs-for-people-with-parkinson-s-disease
#11
Allison L Amateis, Chelsea L Boesel, Bryan P Ehnert, Abby S Evans, Katheryn E Hurst, Katie L Marek, Amanda C Sullivan, Kathryn R Zalewski, Wendy E Huddleston
PURPOSE: Community-based exercise can support long-term management of Parkinson's disease, although it is not known if personal goals are met in these programs. The objectives of this study were to: (1) examine the goals of community based exercise programs from the participant and instructor perspectives; (2) establish the extent to which these programs meet self-described exercise outcomes; and (3) explore participant and instructor perspectives on barriers to meeting exercise expectations...
May 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29785199/physical-exercise-for-parkinson-s-disease-clinical-and-experimental-evidence
#12
REVIEW
Alessandro Oliveira de Carvalho, Alberto Souza Sá Filho, Eric Murillo-Rodriguez, Nuno Barbosa Rocha, Mauro Giovanni Carta, Sergio Machado
Background: National projections about the increase in the elderly population over 60 years bring with it an increase in the number of people affected by Parkinson's Disease (PD), making it an important public health problem. Therefore, the establishment of effective strategies for intervention in people with PD needs to be more clearly investigated. Objective: The study aimed to report the effectiveness of exercise on functional capacity and neurobiological mechanisms in people with PD...
2018: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29779721/evaluation-of-an-ontology-based-system-for-computerized-cognitive-rehabilitation
#13
Anna Alloni, Silvana Quaglini, Silvia Panzarasa, Elena Sinforiani, Sara Bernini
OBJECTIVES: This paper describes the results of a randomized clinical trial about the effectiveness of a computerized rehabilitation treatment on a sample of 31 patients affected by Parkinson disease. METHODS: Computerized exercises were administered by the therapists to the intervention group (n = 17) through the CoRe tool, which automatically generates a big variety of exercises leveraging on a stimuli set (words, sounds and images) organized into a dedicated ontology...
July 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29754837/effects-of-exercise-on-gait-and-motor-imagery-in-people-with-parkinson-disease-and-freezing-of-gait
#14
Peter S Myers, Marie E McNeely, Kristen A Pickett, Ryan P Duncan, Gammon M Earhart
INTRODUCTION: Exercise improves gait in Parkinson disease (PD), but whether exercise differentially affects people with PD with (freezers) and without freezing of gait (non-freezers) remains unclear. This study examines exercise's effects on gait performance, neural correlates related to these effects, and potential neural activation differences between freezers and non-freezers during motor imagery (MI) of gait. METHODS: Thirty-seven participants from a larger exercise intervention completed behavioral assessments and functional magnetic resonance imaging (fMRI) scans before and after a 12-week exercise intervention...
May 8, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29753113/cardiovascular-responses-during-resistance-exercise-in-patients-with-parkinson-disease
#15
Roberto Miyasato, Carla Silva-Batista, Tiago Peçanha, David A Low, Marco T de Mello, Maria E Piemonte, Carlos Ugrinowitsch, Cláudia L M Forjaz, Hélcio Kanegusuku
BACKGROUND: Patients with Parkinson disease (PD) present cardiovascular autonomic dysfunction which impairs blood pressure control. However, cardiovascular responses during resistance exercise are unknown in these patients. OBJECTIVE: Investigate the cardiovascular responses during resistance exercise performed with different muscle masses, in patients with PD. DESIGN: Two groups, repeated-measures design. SETTING: Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo...
May 9, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29746848/nitric-oxide-alterations-in-cardiovascular-system-of-rats-with-parkinsonism-induced-by-6-ohda-and-submitted-to-previous-exercise
#16
Lorena de Jager, Eric Diego Turossi Amorim, Bruno Fernando Cruz Lucchetti, Fernanda Novi Cortegoso Lopes, Carlos Cesar Crestani, Phileno Pinge-Filho, Marli Cardoso Martins-Pinge
Studies showed that physical exercise decreases the risk of developing Parkinson's disease (PD) as slowing its progression. During aerobic training, nitric oxide (NO) increases in the substantia nigra pars compacta (SNpc) of individuals with PD. However, no study has evaluated the effects of exercise on peripheral NO levels and its modulatory effects on cardiovascular dysfunctions of subjects with PD. Trained (T) or sedentary (S) animals underwent stereotactic surgery for bilateral 6-hydroxydopamine (6-OHDA) or vehicle microinfusion (Sham group)...
May 7, 2018: Life Sciences
https://www.readbyqxmd.com/read/29746402/update-in-therapeutic-strategies-for-parkinson-s-disease
#17
Jaime Kulisevsky, Lais Oliveira, Susan H Fox
PURPOSE OF REVIEW: To review recent advances in therapeutics for motor and nonmotor symptoms of Parkinson's disease. RECENT FINDINGS: Neuroprotection remains a large area of investigation with preliminary safety data on alpha synuclein immunotherapy and glucagon-like peptide-1 agonists. Novel Monoamine Oxidase B and Caetchol-O-methyltransferase-inhibitors for motor fluctuations have shown benefit and are recently approved for clinical use. Long-acting amantadine has also been approved to reduce dyskinesia...
May 8, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29737443/romberg-ratio-coefficient-in-quiet-stance-and-postural-control-in-parkinson-s-disease
#18
Teresa Paolucci, Marco Iosa, Giovanni Morone, Matteo Delle Fratte, Stefano Paolucci, Vincenzo M Saraceni, Ciro Villani
The aim of this study was to determine the function of visual afference in postural control in Parkinson patients. We enrolled 29 patients and 30 healthy controls. The stabilometry test was performed for posture and balance and Romberg ratio coefficients were calculated. In addition, the Berg Balance Scale and the 6-Minute Walking Test were administered to assess balance and functional exercise capacity; the Unified Parkinson's Disease Rating Scale was used to determine the stage of the disease; and the Short Form (SF)-36 Health Survey was given to collect information on quality of life...
May 8, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29729611/accuracy-of-wearable-physical-activity-trackers-in-people-with-parkinson-s-disease
#19
Robyn M Lamont, Hannah L Daniel, Caitlyn L Payne, Sandra G Brauer
INTRODUCTION: The purpose of this study was to determine the accuracy of the Fitbit Charge HR™ and Garmin vívosmart® HR in measuring steps and reflecting intensity of activity in people with Parkinson's disease (PD). METHODS: Thirty-three people with mild-moderate PD performed six, two-minute indoor walks at their self-selected walking pace, and at target cadences of 60, 80, 100, 120 and 140 beats/min. A 500 m outdoor walk with terrain challenges was also performed...
April 24, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29725348/dynamic-neuro-cognitive-imagery-improves-mental-imagery-ability-disease-severity-and-motor-and-cognitive-functions-in-people-with-parkinson-s-disease
#20
Amit Abraham, Ariel Hart, Isaac Andrade, Madeleine E Hackney
People with Parkinson's disease (PD) experience kinesthetic deficits, which affect motor and nonmotor functions, including mental imagery. Imagery training is a recommended, yet underresearched, approach in PD rehabilitation. Dynamic Neuro-Cognitive Imagery (DNI™) is a codified method for imagery training. Twenty subjects with idiopathic PD (Hoehn and Yahr stages I-III) were randomly allocated into DNI training (experimental; n = 10) or in-home learning and exercise program (control; n = 10). Both groups completed at least 16 hours of training within two weeks...
2018: Neural Plasticity
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