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Demodex mite

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https://www.readbyqxmd.com/read/29648591/analysis-of-the-effect-of-temperature-on-protein-abundance-in-demodex-associated-bacillus-oleronius
#1
Amie Maher, Kara Staunton, Kevin Kavanagh
A potential role for bacteria in the induction of rosacea has been suggested. The aim of this work was to characterize the effect of temperature on the production of immunostimulatory proteins by Bacillus oleronius-a bacterium to which rosacea patients show sera reactivity and which was originally isolated from a Demodex mite from a rosacea patient. The affected skin of rosacea patients is at a higher temperature than unaffected skin and it was postulated that this might alter the protein expression pattern of B...
April 10, 2018: Pathogens and Disease
https://www.readbyqxmd.com/read/29603309/the-status-of-demodex-cornei-description-of-the-species-and-developmental-stages-and-data-on-demodecid-mites-in-the-domestic-dog-canis-lupus-familiaris
#2
J N Izdebska, L Rolbiecki
Demodecosis canina is one of the most important dog parasitoses, but its aetiology is still not well known. There are currently two known species of demodecid mite specific to the domestic dog Canis lupus familiaris Linnaeus, 1758 (Carnivora: Canidae). These are Demodex canis Leydig, 1859 (Acariformes: Demodecidae) and Demodex injai Desch & Hillier, 2003. There have also been many reports of the so-called 'short form', considered to be a separate species functioning under the name Demodex cornei nomen nudum, for which, however, no formal valid description has been documented...
March 30, 2018: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/29593809/the-impact-of-age-sex-blepharitis-rosacea-and-rheumatoid-arthritis-on-demodex-mite-infection
#3
Aleksandra Sędzikowska, Maciej Osęka, Piotr Skopiński
Introduction: Two human-specific Demodex species have been described: Demodex folliculorum and Demodex brevis . A medical condition caused by the presence of Demodex is called demodicosis. Material and methods: The study material comprised eyelashes collected from 1499 patients. Results: Demodex sp. infection was revealed in 47% of patients (487 women and 216 men). We determined the following rates of infection by age groups: 1-25 (8% of infected subjects), 26-40 (36%), 41-55 (50%), 56-70 (67%), over 70 (77%)...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29555007/comparison-of-diagnostic-methods-and-sampling-sites-for-the-detection-of-demodex-musculi
#4
Melissa A Nashat, Rodolfo J Ricart Arbona, Elyn R Riedel, Olga Francino, Lluis Ferrer, Kerith R Luchins, Neil S Lipman
Demodex mites are microscopic, cigar-shaped, follicular mites often regarded as commensal microfauna in mammals. Although Demodex spp. can cause dermatologic disease in any immunocompromised mammal, they are rarely reported in laboratory mice. Recent identification of Demodex musculi in a colony of immunodeficient mice with dermatitis afforded us the opportunity to investigate the comparative sensitivity of 4 antemortem diagnostic techniques to detect D. musculi-superficial skin scrape (SSS), tape impression (TI), fur pluck (FP), and deep skin scrape (DSS)-which we performed on 4 anatomic sites (face, interscapular region [IS], caudal ventrum [CV], and caudal dorsum [CD]) in 46 mice...
March 1, 2018: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/29544355/ivermectin-1-cd5024-for-the-treatment-of-rosacea
#5
Dev R Sahni, Steven R Feldman, Sarah L Taylor
Rosacea is a chronic and recurrent disease with a variety of cutaneous manifestations. The disorder is a centrofacial inflammatory dermatosis with significant financial, physical and psychological impacts. There are a number of topical, oral and systemic treatments available. Yet, treatment for rosacea remains difficult. The multifactorial nature of the disease combined with an incomplete understanding of the pathophysiology is challenging for providers and patients. Areas covered: This article provides an in-depth review of rosacea treatment and emerging use of ivermectin 1% cream for papulopustular rosacea based on multiple clinical trials...
April 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29532463/demodex-mites-modulate-sebocyte-immune-reaction-possible-role-in-the-pathogenesis-of-rosacea
#6
N Lacey, A Russell-Hallinan, C C Zouboulis, F C Powell
Rosacea is a common facial skin disorder affecting middle-aged adults. Its aetiology is unknown and pathogenesis uncertain. Activation of the host innate immune response has been identified as important. The Demodex mite population in the skin of these patients is significantly higher than in subjects with normal skin suggesting they may be of etiological importance in this disorder. Little is known of the role of these mites in human skin and their potential to interact with the host immune system has not been elucidated...
March 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29498895/assays-for-detection-and-identification-of-the-causative-agent-of-mange-in-free-ranging-black-bears-ursus-americanus
#7
Sarah K Peltier, Justin D Brown, Mark A Ternent, Heather Fenton, Kevin D Niedringhaus, Michael J Yabsley
Three mite species ( Demodex ursi, Ursicoptes americanus, and Sarcoptes scabiei) have been associated with mange in black bears ( Ursus americanus). Since the early 1990s, the number and geographic distribution of mange cases in black bears in Pennsylvania has increased; however, the causative mites have yet to be completely defined. We evaluated several diagnostic approaches for detection and identification of mites in 72 black bears with severe lesions consistent with mange. Sarcoptes scabiei was morphologically identified in skin scrapes from 66 of the bears; no mites were identified in the remaining six...
March 2, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29478301/papulopustular-rosacea-and-rosacea-like-demodicosis-two-phenotypes-of-the-same-disease
#8
F M N Forton, V De Maertelaer
BACKGROUND: Papulopustular rosacea and rosacea-like demodicosis have numerous similarities but they are generally considered as two distinct entities, mainly because the causal role of the Demodex mite in the development of rosacea is not yet widely accepted. Several clinical characteristics are traditionally considered to differentiate the two conditions; for example, papulopustular rosacea is typically characterised by central facial papulopustules and persistent erythema, whereas small superficial papulopustules and follicular scales rather suggest rosacea-like demodicosis...
February 25, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29469533/-investigation-on-demodex-infection-status-and-influencing-factors-in-medical-students-in-wuhu-city
#9
Zhao Ru-Juan, Yang Xue-Rong, Zhao Ying, Pan Yi-Ning, Xu Wen-Ting, Hu Ting-Ting, Yang Yan, Zhao Jin-Hong
OBJECTIVE: To investigate the Demodex infection status and influencing factors in medical students in Wuhu City. METHODS: The mite specimens were collected by the cellophane tape method, and the influencing factors were investigated through the questionnaires. RESULTS: A total of 316 medical students were surveyed, 117 students were infected with Demodex mite, and the total infection rate was 37.03%. There was no significant difference between the male and female in the infection rate ( χ 2 = 0...
April 28, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29426737/-demodex-genus-colonizing-parasites-of-healthy-people-or-mites-associated-with-ocular-pathology
#10
Florencia Mongi, Laura Laconte, Rodolfo D Casero
Demodex folliculorum and Demodex brevis are mites that are responsible for human demodicosis affecting skin and frequently linked to ocular diseasess. The aim of this work was to determine the association between Demodex sp. and eyelid and eyelash diseases and to establish the predisposing factors for acquiring this parasitic disease. Eyelashes from symptomatic and asymptomatic patients (n=72) between 9 and 82 years old were analyzed, where 53% were positive for Demodex sp., of which 66% manifested ocular symptoms and pathologies, blepharitis and dry eye being prevalent...
February 6, 2018: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29380184/ocular-demodex-folliculorum-prevalence-and-associated-symptoms-in-an-irish-population
#11
Orla Murphy, Veronica O'Dwyer, Aoife Lloyd-McKernan
PURPOSE: To investigate the prevalence of ocular Demodex folliculorum (DF) in an Irish population. To validate a modified Ocular Surface Disease Index questionnaire and employ it to evaluate the relationship between dry eye symptoms and the presence of DF. METHODS: One hundred and fifty-six subjects were enrolled in an epidemiological cross-sectional prevalence study. Each subject completed a novel questionnaire on ocular symptoms and was assessed for the presence of DF...
January 29, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29364436/investigation-of-demodex-folliculorum-frequency-in-patients-with-polycystic-ovary-syndrome
#12
Ayla Eser, Seval Erpolat, Ikbal Kaygusuz, Hatice Balci, Aydin Kosus
BACKGROUND: Background: Demodex mites are acari that reside in the pilosebaceous unit of the skin and have been associated with skin disorders. OBJECTIVE: The objective of this study was to investigate the prevalence of Demodex folliculorum (D. folliculorum) mites in polycystic ovary syndrome patients as well as to examine the relationship between Demodex infestation and the presence of acne and oily or dry skin types in polycystic ovary syndrome patients. METHODS: 41 polycystic ovary syndrome patients and 47 non-polycystic ovary syndrome control subjects were enrolled in the study...
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29283119/demodex-and-rosacea-is-there-a-relationship
#13
Diana Gonzalez-Hinojosa, Alejandro Jaime-Villalonga, Gustavo Aguilar-Montes, Lorena Lammoglia-Ordiales
PURPOSE: The objective of the study is to compare the frequency of Demodex on the eyelash follicle of patients with rosacea and referents without rosacea or ophthalmological disorders. METHODS: This is a comparative, open, observational, and cross-sectional study that included 41 patients diagnosed with rosacea and 41 referents without rosacea diagnosis or ophthalmic alterations. The individuals underwent a slit-lamp examination in which two eyelashes per eyelid were removed with fine forceps...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29194776/endosymbiosis-and-its-significance-in-dermatology
#14
REVIEW
K Kubiak, H Sielawa, W Chen, E Dzika
Proposed at the beginning of the twentieth century to explain the origin of eukaryotic organelles from prokaryotes, endosymbiosis is now medically defined by various interaction patterns between microorganisms and their residing hosts, best exemplified by the bacterial endosymbiont Wolbachia identified in arthropods and filarial nematodes, which can influence normal development, reproduction, survival and transmission of the hosts. Based on the transmission modes, vertical or horizontal, and the function of the endosymbionts, the host-symbiont dependence can be divided into primary or secondary...
March 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29089049/efficacy-of-lotilaner-credelio%C3%A2-a-novel-oral-isoxazoline-against-naturally-occurring-mange-mite-infestations-in-dogs-caused-by-demodex-spp
#15
Daniel E Snyder, Scott Wiseman, Julian E Liebenberg
BACKGROUND: The oral systemic efficacy of lotilaner (Credelio™, Elanco) was evaluated against Demodex spp. in naturally infested dogs with generalized demodicosis. METHODS: In this study, 10 dogs with clinical signs of generalized demodicosis and positive for Demodex spp. mites based on skin scrapings were assigned to a single group orally treated with lotilaner (minimum dose of 20 mg/kg) on Days 0, 28 and 56. RESULTS: For lotilaner-treated dogs, pre-treatment mite counts based on skin scrapings performed at five different sites were reduced by > 99...
November 1, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29066489/demodex-as-a-delivery-vector-for-topical-targeted-medications-in-the-skin-for-early-melanoma-and-non-melanoma-skin-cancer
#16
Stephen L Strobel
The potential utilization of Demodex mites as delivery vectors for cytotoxic medications directed to early skin cancer is proposed. Potential benefits, proof of concept, and limitations are discussed.
September 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29055903/significant-correlation-between-meibomian-gland-dysfunction-and-keratitis-in-young-patients-with-demodex-brevis-infestation
#17
Lingyi Liang, Yan Liu, Xiaohu Ding, Hongmin Ke, Chuan Chen, Scheffer C G Tseng
AIMS: To report the clinical characteristics and correlation between meibomian gland dysfunction (MGD) and keratitis in young patients with ocular demodicosis. METHODS: Observational case series of 60 patients younger than 35 years with ocular demodicosis, of which the diagnosis was based on microscopic counting of Demodex folliculorum and D. brevis of epilated lashes. Severity of keratitis and MGD was graded by photography and meibography, respectively, in a masked fashion...
October 21, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29054722/the-eyelids-and-tear-film-in-contact-lens-discomfort
#18
Jaya Sowjanya Siddireddy, Ajay Kumar Vijay, Jacqueline Tan, Mark Willcox
PURPOSE: To investigate characteristics of the eyelid margins, meibomian glands and the tear film of contact lens wearers, and to determine whether these characteristics were related to symptoms of contact lens discomfort. METHODS: A cross sectional study was performed on thirty existing daily wear soft contact lens wearers (6 male; 24 female) with median age of 23 years (range 18-41). Eyelid signs and tear film characteristics were evaluated during a single visit and subjects completed the contact lens and dry eye questionnaire (CLDEQ-8) to evaluate ocular discomfort...
October 17, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29035242/the-effect-of-skin-sebum-ph-and-moisture-on-demodex-infestation-in-acne-vulgaris-and-rosacea-patients
#19
Nergiz Turan, Yelda Kapıcıoğlu, Gülbahar Saraç
OBJECTIVE: Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. in acne vulgaris and rosacea patients. METHODS: This study focused on 30 patients each with acne vulgaris and rosacea. As a control group, 60 healthy individuals were included. RESULTS: In acne vulgaris patients, when compared to those with Demodex mite more than 5 /cm2 in each area, less than 5/cm2 were found to be oily, acidic, dry or very dry...
September 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28940244/demodicosis-in-two-patients-with-a-previous-history-of-langerhans-cell-histiocytosis
#20
Marcial Álvarez-Salafranca, Asunción Vicente, Carolina Prat Torres, Andrea Combalia, Manuel Monsonís, Veronica Paola Celis-Passini, María Antonia González-Enseñat
Demodex mites are commensal organisms rarely found in healthy children. Human demodicosis can be classified as a primary or a secondary form. The secondary form in children usually affects severely immunodepressed children. To our knowledge, this is the first report of human demodicosis associated with Langerhans cell histiocytosis. These cases show that this skin disorder can occur months after completing chemotherapy, without recurrence of the systemic disease.
November 2017: Pediatric Dermatology
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