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Demodex mite

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https://www.readbyqxmd.com/read/29900778/successful-treatment-of-generalized-demodicosis-in-red-handed-tamarins-saguinus-midas-using-a-single-administration-of-oral-fluralaner
#1
Sarah M Churgin, Foo Khong Lee, Kristin Groenvold, Ramesh C Kovi, Kam Yan Cheung, Paolo R Martelli, Cert Zoo
  Two adult sibling red-handed tamarins ( Saguinus midas) presented with weight loss and multifocal skin masses. A skin biopsy revealed pyogranulomatous dermatitis with intrafollicular Demodex sp. mites. Subsequent skin scrapes confirmed the presence of live mites within lesions. Initial treatment with topical and oral ivermectin was unsuccessful, and lesions continued to progress. A single dose of fluralaner (Bravecto®, Merck Animal Health, Kenilworth, New Jersey, 07033, USA; 28.125 mg po) was administered to each animal approximately 5 mo after initial presentation...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29883220/the-rapid-effect-of-pulsed-dye-laser-on-demodex-density-of-facial-skin
#2
Ragıp Ertaş, Ozan Yaman, M Reşat Akkuş, Emin Özlü, Atıl Avcı, Yılmaz Ulaş, Kemal Ozyurt, Mustafa Atasoy
BACKGROUND: Recently, treatment with acaricides, which is aimed at reducing excessive proliferation of demodex mites, has gained popularity due to its providing a significant improvement in the symptoms of diseases, such as rosacea, seborrhoeic dermatitis, and perioral dermatitis. The effect of IPL on demodex mites was reported in skin biopsy specimens in three patients; however, to the best of our knowledge, no study exists to date, which evaluates the effect of pulsed dye laser (PDL) on demodex density (Dd) in larger patient group...
June 8, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29728826/skin-mites-in-mice-mus-musculus-high-prevalence-of-myobia-sp-acari-arachnida-in-robertsonian-mice
#3
Natalia Sastre, Oriol Calvete, Jessica Martínez-Vargas, Nuria Medarde, Joaquim Casellas, Laura Altet, Armand Sánchez, Olga Francino, Jacint Ventura
Myobia sp. and Demodex sp. are two skin mites that infest mice, particularly immunodeficient or transgenic lab mice. In the present study, wild house mice from five localities from the Barcelona Roberstonian system were analysed in order to detect skin mites and compare their prevalence between standard (2n = 40) and Robertsonian mice (2n > 40). We found and identified skin mites through real-time qPCR by comparing sequences from the mitochondrial 16S rRNA and the nuclear 18S rRNA genes since no sequences are available so far using the mitochondrial gene...
May 4, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29713140/better-detection-of-demodex-mites-by-l%C3%A3-ffler-s-alkaline-methylene-blue-staining-in-patients-with-blepharitis
#4
Katsuji Kiuchi
Purpose: To determine whether the Löffler's alkaline methylene blue staining method is better than no staining in detecting Demodex mites in the eyelashes of patients with blepharitis. Materials and methods: Eyelashes were collected from 22 patients with blepharitis. The mean age of the patients was 82.5±6.2 years (± SD) with a range from 71 to 93 years. Eyelashes were epilated by forceps and placed individually on microscope slides. The number of Demodex mites was determined by conventional optical microscopy before and immediately after the addition of the methylene blue staining solution...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29667560/can-the-tea-tree-oil-australian-native-plant-melaleuca-alternifolia-cheel-be-an-alternative-treatment-for-human-demodicosis-on-skin
#5
Nelson Siu Kei Lam, Xin Xin Long, Robert C Griffin, Mu-Kai Chen, James Cg Doery
Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes the topical treatments of TTO and T4O in human demodicosis, their possible mechanism of actions, side-effects and potential resistance in treating this condition. Although current treatments other than TTO and T4O are relatively effective in controlling the demodex mite population and the related symptoms, more research on the efficacy and drug delivery technology is needed in order to assess its potential as an alternative treatment with minimal side-effect profile, low toxicity and low risk of demodex resistance...
April 18, 2018: Parasitology
https://www.readbyqxmd.com/read/29648591/analysis-of-the-effect-of-temperature-on-protein-abundance-in-demodex-associated-bacillus-oleronius
#6
Amie Maher, Kara Staunton, Kevin Kavanagh
A potential role for bacteria in the induction of rosacea has been suggested. The aim of this work was to characterise the effect of temperature on the production of immunostimulatory proteins by Bacillus oleronius-a bacterium to which rosacea patients show sera reactivity and which was originally isolated from a Demodex mite from a rosacea patient. The affected skin of rosacea patients is at a higher temperature than unaffected skin, and it was postulated that this might alter the protein expression pattern of B...
June 1, 2018: Pathogens and Disease
https://www.readbyqxmd.com/read/29603309/the-status-of-demodex-cornei-description-of-the-species-and-developmental-stages-and-data-on-demodecid-mites-in-the-domestic-dog-canis-lupus-familiaris
#7
J N Izdebska, L Rolbiecki
Demodecosis canina is one of the most important dog parasitoses, but its aetiology is still not well known. There are currently two known species of demodecid mite specific to the domestic dog Canis lupus familiaris Linnaeus, 1758 (Carnivora: Canidae). These are Demodex canis Leydig, 1859 (Acariformes: Demodecidae) and Demodex injai Desch & Hillier, 2003. There have also been many reports of the so-called 'short form', considered to be a separate species functioning under the name Demodex cornei nomen nudum, for which, however, no formal valid description has been documented...
March 30, 2018: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/29593809/the-impact-of-age-sex-blepharitis-rosacea-and-rheumatoid-arthritis-on-demodex-mite-infection
#8
Aleksandra Sędzikowska, Maciej Osęka, Piotr Skopiński
Introduction: Two human-specific Demodex species have been described: Demodex folliculorum and Demodex brevis . A medical condition caused by the presence of Demodex is called demodicosis. Material and methods: The study material comprised eyelashes collected from 1499 patients. Results: Demodex sp. infection was revealed in 47% of patients (487 women and 216 men). We determined the following rates of infection by age groups: 1-25 (8% of infected subjects), 26-40 (36%), 41-55 (50%), 56-70 (67%), over 70 (77%)...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29555007/comparison-of-diagnostic-methods-and-sampling-sites-for-the-detection-of-demodex-musculi
#9
Melissa A Nashat, Rodolfo J Ricart Arbona, Elyn R Riedel, Olga Francino, Lluis Ferrer, Kerith R Luchins, Neil S Lipman
Demodex mites are microscopic, cigar-shaped, follicular mites often regarded as commensal microfauna in mammals. Although Demodex spp. can cause dermatologic disease in any immunocompromised mammal, they are rarely reported in laboratory mice. Recent identification of Demodex musculi in a colony of immunodeficient mice with dermatitis afforded us the opportunity to investigate the comparative sensitivity of 4 antemortem diagnostic techniques to detect D. musculi-superficial skin scrape (SSS), tape impression (TI), fur pluck (FP), and deep skin scrape (DSS)-which we performed on 4 anatomic sites (face, interscapular region [IS], caudal ventrum [CV], and caudal dorsum [CD]) in 46 mice...
March 1, 2018: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/29544355/ivermectin-1-cd5024-for-the-treatment-of-rosacea
#10
Dev R Sahni, Steven R Feldman, Sarah L Taylor
Rosacea is a chronic and recurrent disease with a variety of cutaneous manifestations. The disorder is a centrofacial inflammatory dermatosis with significant financial, physical and psychological impacts. There are a number of topical, oral and systemic treatments available. Yet, treatment for rosacea remains difficult. The multifactorial nature of the disease combined with an incomplete understanding of the pathophysiology is challenging for providers and patients. Areas covered: This article provides an in-depth review of rosacea treatment and emerging use of ivermectin 1% cream for papulopustular rosacea based on multiple clinical trials...
April 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29532463/demodex-mites-modulate-sebocyte-immune-reaction-possible-role-in-the-pathogenesis-of-rosacea
#11
N Lacey, A Russell-Hallinan, C C Zouboulis, F C Powell
Rosacea is a common facial skin disorder affecting middle-aged adults. Its aetiology is unknown and pathogenesis uncertain. Activation of the host innate immune response has been identified as important. The Demodex mite population in the skin of these patients is significantly higher than in subjects with normal skin suggesting they may be of etiological importance in this disorder. Little is known of the role of these mites in human skin and their potential to interact with the host immune system has not been elucidated...
March 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29498895/assays-for-detection-and-identification-of-the-causative-agent-of-mange-in-free-ranging-black-bears-ursus-americanus
#12
Sarah K Peltier, Justin D Brown, Mark A Ternent, Heather Fenton, Kevin D Niedringhaus, Michael J Yabsley
Three mite species ( Demodex ursi, Ursicoptes americanus, and Sarcoptes scabiei) have been associated with mange in black bears ( Ursus americanus). Since the early 1990s, the number and geographic distribution of mange cases in black bears in Pennsylvania has increased; however, the causative mites have yet to be completely defined. We evaluated several diagnostic approaches for detection and identification of mites in 72 black bears with severe lesions consistent with mange. Sarcoptes scabiei was morphologically identified in skin scrapes from 66 of the bears; no mites were identified in the remaining six...
March 2, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29478301/papulopustular-rosacea-and-rosacea-like-demodicosis-two-phenotypes-of-the-same-disease
#13
F M N Forton, V De Maertelaer
BACKGROUND: Papulopustular rosacea and rosacea-like demodicosis have numerous similarities, but they are generally considered as two distinct entities, mainly because the causal role of the Demodex mite in the development of rosacea is not yet widely accepted. Several clinical characteristics are traditionally considered to differentiate the two conditions; for example, papulopustular rosacea is typically characterized by central facial papulopustules and persistent erythema, whereas small superficial papulopustules and follicular scales rather suggest rosacea-like demodicosis...
February 25, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29469533/-investigation-on-demodex-infection-status-and-influencing-factors-in-medical-students-in-wuhu-city
#14
Zhao Ru-Juan, Yang Xue-Rong, Zhao Ying, Pan Yi-Ning, Xu Wen-Ting, Hu Ting-Ting, Yang Yan, Zhao Jin-Hong
OBJECTIVE: To investigate the Demodex infection status and influencing factors in medical students in Wuhu City. METHODS: The mite specimens were collected by the cellophane tape method, and the influencing factors were investigated through the questionnaires. RESULTS: A total of 316 medical students were surveyed, 117 students were infected with Demodex mite, and the total infection rate was 37.03%. There was no significant difference between the male and female in the infection rate ( χ 2 = 0...
April 28, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29426737/-demodex-genus-colonizing-parasites-of-healthy-people-or-mites-associated-with-ocular-pathology
#15
Florencia Mongi, Laura Laconte, Rodolfo D Casero
Demodex folliculorum and Demodex brevis are mites that are responsible for human demodicosis affecting skin and frequently linked to ocular diseasess. The aim of this work was to determine the association between Demodex sp. and eyelid and eyelash diseases and to establish the predisposing factors for acquiring this parasitic disease. Eyelashes from symptomatic and asymptomatic patients (n=72) between 9 and 82 years old were analyzed, where 53% were positive for Demodex sp., of which 66% manifested ocular symptoms and pathologies, blepharitis and dry eye being prevalent...
February 6, 2018: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29380184/ocular-demodex-folliculorum-prevalence-and-associated-symptoms-in-an-irish-population
#16
Orla Murphy, Veronica O'Dwyer, Aoife Lloyd-McKernan
PURPOSE: To investigate the prevalence of ocular Demodex folliculorum (DF) in an Irish population. To validate a modified Ocular Surface Disease Index questionnaire and employ it to evaluate the relationship between dry eye symptoms and the presence of DF. METHODS: One hundred and fifty-six subjects were enrolled in an epidemiological cross-sectional prevalence study. Each subject completed a novel questionnaire on ocular symptoms and was assessed for the presence of DF...
January 29, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29364436/investigation-of-demodex-folliculorum-frequency-in-patients-with-polycystic-ovary-syndrome
#17
Ayla Eser, Seval Erpolat, Ikbal Kaygusuz, Hatice Balci, Aydin Kosus
BACKGROUND: Background: Demodex mites are acari that reside in the pilosebaceous unit of the skin and have been associated with skin disorders. OBJECTIVE: The objective of this study was to investigate the prevalence of Demodex folliculorum (D. folliculorum) mites in polycystic ovary syndrome patients as well as to examine the relationship between Demodex infestation and the presence of acne and oily or dry skin types in polycystic ovary syndrome patients. METHODS: 41 polycystic ovary syndrome patients and 47 non-polycystic ovary syndrome control subjects were enrolled in the study...
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29283119/demodex-and-rosacea-is-there-a-relationship
#18
COMPARATIVE STUDY
Diana Gonzalez-Hinojosa, Alejandro Jaime-Villalonga, Gustavo Aguilar-Montes, Lorena Lammoglia-Ordiales
PURPOSE: The objective of the study is to compare the frequency of Demodex on the eyelash follicle of patients with rosacea and referents without rosacea or ophthalmological disorders. METHODS: This is a comparative, open, observational, and cross-sectional study that included 41 patients diagnosed with rosacea and 41 referents without rosacea diagnosis or ophthalmic alterations. The individuals underwent a slit-lamp examination in which two eyelashes per eyelid were removed with fine forceps...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29194776/endosymbiosis-and-its-significance-in-dermatology
#19
REVIEW
K Kubiak, H Sielawa, W Chen, E Dzika
Proposed at the beginning of the twentieth century to explain the origin of eukaryotic organelles from prokaryotes, endosymbiosis is now medically defined by various interaction patterns between microorganisms and their residing hosts, best exemplified by the bacterial endosymbiont Wolbachia identified in arthropods and filarial nematodes, which can influence normal development, reproduction, survival and transmission of the hosts. Based on the transmission modes, vertical or horizontal, and the function of the endosymbionts, the host-symbiont dependence can be divided into primary or secondary...
March 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29089049/efficacy-of-lotilaner-credelio%C3%A2-a-novel-oral-isoxazoline-against-naturally-occurring-mange-mite-infestations-in-dogs-caused-by-demodex-spp
#20
Daniel E Snyder, Scott Wiseman, Julian E Liebenberg
BACKGROUND: The oral systemic efficacy of lotilaner (Credelio™, Elanco) was evaluated against Demodex spp. in naturally infested dogs with generalized demodicosis. METHODS: In this study, 10 dogs with clinical signs of generalized demodicosis and positive for Demodex spp. mites based on skin scrapings were assigned to a single group orally treated with lotilaner (minimum dose of 20 mg/kg) on Days 0, 28 and 56. RESULTS: For lotilaner-treated dogs, pre-treatment mite counts based on skin scrapings performed at five different sites were reduced by > 99...
November 1, 2017: Parasites & Vectors
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