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Pulmonary arterial hypertention

Mengxi Li, Jiaze Shu, Wenju Lu, Nanshan Zhong, Jian Wang
No abstract text is available yet for this article.
October 2014: Chinese Journal of Tuberculosis and Respiratory Diseases
Hua Liu, Tao-Tao Huang, Jian-Hua Lin
BACKGROUND: Pregnant women with heart disease are at high risk. Studies of risk factors of these patients are of great significance to improve maternal and fetal outcomes. In this paper, we try to discuss the main risk factors of cardiac events in pregnant women with heart disease and to establish a risk assessment system. METHODS: A retrospective analysis was carried out for pregnancies in 1741 women with heart disease who delivered in Shanghai Obstetrical Cardiology Intensive Care Center between January 1993 and September 2010...
October 2012: Chinese Medical Journal
Zhuang Tian, Yong-Tai Liu, Quan Fang, Chao Ni, Tai-Bo Chen, Li-Gang Fang, Peng Gao, Xiu-Chun Jiang, Meng-Tao Li, Xiao-Feng Zeng
BACKGROUND: Hemodynamic evaluation is crucial for the management of patients with pulmonary hypertention. Clinicians often prefer a rapid and non-invasive method. This study aimed to examine the feasibility of transthoracic echocardiography for the measurements of hemodynamic parameters in patients with pulmonary hypertension. METHODS: A prospective single-center study was conducted among 42 patients with pulmonary hypertension caused by different diseases. Transthoracic echocardiography and right-heart catheterization were performed within 24 hours...
June 2011: Chinese Medical Journal
Yo Ueda, Yuko Takahashi, Hiroyuki Yamashita, Hiroshi Kaneko, Akio Mimori
We report a 43-year-old female who developed pulmonary arterial hypertension (PAH) during intensive immunosuppressive therapy for systematic lupus erythematosus (SLE). She was diagnosed as SLE at the age of 32 years based on serological and hematological abnormalities, oral ulcers, and facial erythema. She experienced frequent flare-ups of disseminated discoid lupus between the ages of 33 and 36 years and developed immune thrombocytopenia at the age of 39 years. In 2007 when she was 43 years old, she developed lupus nephritis (LN) with elevated serum anti-double stranded DNA antibodies and urine protein of less than 1 g/day...
2011: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
W J Randerath
Diagnosis and treatment of sleep related breathing disorders have become an essential challenge of internal medicine. They are highly important clinically because of the impairment of daytime performance, attention and concentration with elevated risk of accidents in workplace and traffic and because of their consequences on cardiovascular and metabolic disorders. The obstructive sleep apnoea syndrome (OSAS) has proven to be one of the most important risk factors for arteriosclerosis, especially in the cerebral vessels...
April 2011: Deutsche Medizinische Wochenschrift
Mayuko Uehara, Yosuke Kuroda, Syunsuke Ohori, Toru Mawatari, Kiyofumi Morishita
Pulmonary trunk aneurysm is generally associated with congenital cardiac defects, pulmonary hypertension, or infection. Idiopathic pulmonary trunk aneurysm without any associated diseases is a rare lesion and has seldom been reported. Here, we report a case of a 68-year-old woman with idiopathic pulmonary trunk aneurysm. The maximum diameter of the aneurysm was 53 mm while she was 142 cm in height. We successfully performed aneurysmorrhaphy and her postoperative course was uneventful. Aneurysmorrhaphy was an effective technique for idiopathic pulmonary trunk aneurysm without pulmonary hypertention...
July 2010: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Antoni Bruzgielewicz, Ewelina Sielska-Badurek, Ewa Osuch-Wójcikiewicz, Marta Grotthuss
INTRODUCTION: Tracheotomy is one of the most oldest operations in surgery. Percutaneous dilational tracheotomy has become increasingly popular as an alternative to standard tracheotomy over the last 30 years. It is particularly useful in patients who require prolonged mechanical ventilation, in the intensive care units. Percutaneous tracheotomy is a technique that can be performed at the bedside. It is cost effective, minimally invasive and can be done rapidly. CASE REPORT: We report a case of subglottic stenosis after percutaneous tracheotomy...
May 2009: Otolaryngologia Polska
Li Wei, Tong Liu, Bin Liu, Xian-Min Wang, Liang Zhao, Tong-Fu Zhou
OBJECTIVE: It has been shown that triptolide can attenuate pulmonary arterial hypertension in rats. This study was designed to investigate the therapeutic effect of triptolide on pulmonary hypertension in rats and possible mechanisms. METHODS: Sixty Sprague-Dawley (SD) rats were randomly divided into 6 groups: normal control, model, continuous triptolide-treated, delayed triptolide-treated and two placebo groups for continuous and delayed fashions (n=10 each). The rats from the last 5 groups were injected with monocrotaline (MCT, 60 mg/kg) on day 7 after left pneumonectomy...
October 2007: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Makoto Takiguchi, M Yashima, T Takeuchi, S Adachi, H Goto, N Kuwabara, T Kuwahara
It is not uncommon that valve disease is complicated with Kawasaki disease (KD). However, it is rare to show normal coronary arteries simultaneously. We experienced a case of valvuloplasty towards the mitral regurgitation (MR) followed immediately after KD showing normal coronary arteries. A 3 year-old-female, with a diagnosis of KD at 4 months after birth, was referred to our hospital 5 months after birth. The echocardiography detected a moderate MR. The preoperative catheterization at 2.5 years old showed grade III MR, enlargement of left atrium and left ventricle, pulmonary capillary wedge pressure (PCWP) = 12 mmHg, left ventricular ejection fraction (LVEF) = 675, and normal coronary arteries...
September 2004: Kyobu Geka. the Japanese Journal of Thoracic Surgery
H Nakano, H Aizawa, H Inoue, S Takata, T Minami, N Hara, T Watanabe, K Sueishi
In March 1995, a 54-year-old woman was admitted to a hospital because of exertional dyspnea and her condition was diagnosed as primary pulmonary hypertension. In September 1996, respiratory difficulty and hemosputum were woted. The chest computed tomographic scan showed diffuse micronodular opacities, and she was admitted to our hospital for examination of other pulmonary conditions giving rise to pulmonary hypertention. However no lung biopsy could be performed, because the pulmonary arterial pressure was too high...
July 2001: Nihon Kokyūki Gakkai Zasshi, the Journal of the Japanese Respiratory Society
B Fang, C Wang, H Dai
OBJECTIVE: To study hemodynamic the effects of intravenous diltiazem on COPD induced pulmonary hypertention. METHODS: 11 cases in exacerbation stage were chosen to study. Swan-Ganz catheterization were taken for hemodynamic monitoring. RESULTS: After the administration of diltiazem, pulmonary vascular resistance, pulmonary pressure, right artrial pressure and heart rate decreased significantly (the extents decreased were 14.0 kPa.s-1.L-1, 0...
October 1998: Zhonghua Yi Xue za Zhi [Chinese medical journal]
X A Li, M Wang, K Lu
Microspheres were injected intraportally to block intrahepatic portal radicals and to produce a new rat model of portal hypertention. Different sized microspheres (15 microns, 40 microns, 80 microns) were injected into the portal vein. The resultant changes in arterial, portal, hepatic venous and splenic pulp pressures were monitored. The results showed that a small-dose injection of 80 microns microspheres (1.8 x 10(5)) produced a steady state portal venous pressure of 2.53 +/- 0.17 kPa, and all rats showed a normal arterial pressure...
January 1997: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
J Liu, P Y Wang, D C Luo, Z H Yu, B Y Sun
The effects of hypoxia on the bovine pulmonary arterial smooth muscle cell (PASM) proliferation and serotonin transporter gene expression were investigated using 3H-Thymidine incorporation, immunocytochemical staining and mRNA dot blot hybridyzation, the results were as follows, PASM 3H-Thymidine incorporation increased in response to anoxia for 24 h (P < 0.05). The anoxia-induced increased in DNA synthesis of PASM was significantly stimulated by 5-HT (100, 10 and 1 mumol/L) (P < 0.001), but 5-HT did not increase 3H-TdR incorporation under normoxic condition...
June 1997: Sheng Li Xue Bao: [Acta Physiologica Sinica]
B Wang, S Cui, B Yang, C Zhou, W Ding
The paper deals with the treatment of the pulmonary artery hypertention in rats caused by monocrotaline with garlicin, liqustrazine and berbamine and studies the relationship between the function and structure of pulmonary artery and pulmonary artery hypertension before and after use of hypotensive agents. The results show that there is a close relationship between the function and structure of pulmonary artery and pulmonary hypertension, and the inhibitory effect of garlicin is the strongest among the three herbal medicines...
December 1996: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
N Nagae, K Yokoyama, Y Okada, M Otutomo
The patient was 43 years old female who was administrated by shortness of breath. Preoperative data including immunological examinations identified as SLE. Cardia angiogram showed PAPVC of the right pulmonary veins returned to the right atrium without ASD. Pulmonary hypertention was found with cardiac catheterizations. Open lung biopsy identified pulmonary hypertention caused by shunt volume load, but not by SLE. Surgical correction was accomplished by creating ASD and constructing a baffle to direct the blood flow from the right pulmonary veins to the left atrium...
April 1989: Rinshō Kyōbu Geka, Japanese Annals of Thoracic Surgery
M Friedman, S Y Wang, F W Sellke, W E Cohn, R M Weintraub, R G Johnson
BACKGROUND: Total cardiopulmonary bypass, in an ovine model, is associated with increased pulmonary thromboxane A2 production, cellular sequestration of white cells and platelets, transient pulmonary hypertention, and increased lung lymph flow and lymph protein clearance when compared with respective findings with partial cardiopulmonary bypass. This study evaluates the effect of neutrophil adhesion blockade on lung injury after cardiopulmonary bypass. METHODS: Two groups of anesthetized sheep were placed on total cardiopulmonary bypass without assisted ventilation...
February 1996: Journal of Thoracic and Cardiovascular Surgery
G J Peckham, W W Fox
Indwelling pulmonary artery catheters were used for continuous monitoring of pulmonary artery pressure in ten infants with severe persistent pulmonary hypertention of the newborn. The labile nature of pulmonary artery pressure, with changes up to 50 mm Hg, was documented. Pulmonary artery pressure in the eight infants with suprasystemic pulmonary hypertension was analyzed at the time of maximum decrease in pressure (mean 36.1 mm Hg) and physiologic measurements were compared over an eight-hour period. During the study period when the infants were hyperventilated, as the Paco2 decreased from 48...
December 1978: Journal of Pediatrics
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