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Ferit Kuscu, Aslihan Ulu, Ayse S Inal, Bedia M Suntur, Hande Aydemir, Serdar Gul, Kenan Ecemis, Suheyla Komur, Behice Kurtaran, Ozlem Ozkan Kuscu, Yesim Tasova
BACKGROUND Improper use of antimicrobials can cause adverse drug events and high costs. The purpose of this study was to investigate the frequency and potential drug-drug interactions associated with antimicrobials among hospitalized patients. MATERIAL AND METHODS This study was conducted on the same day in 5 different hospitals in Turkey. We included patients aged ³18 years who received at least 1 antimicrobial drug and at least 1 of any other drug. The Micromedex® online drug reference system was used to control and describe the interactions...
June 20, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Ze-Tian Shen, Xin-Hu Wu, Bing Li, Jun-Shu Shen, Zhen Wang, Jing Li, Xi-Xu Zhu
The above article, published in the Journal of Cellular and Molecular Medicine on 14 September 2016 in Wiley Online Library (, and in Volume 19, pp. 2136-2142, has been retracted by agreement between the authors, the journal Editor in Chief, Stefan Constantinescu, and John Wiley & Sons Ltd. The retraction has been agreed due to unattributed overlap of the language used in the "Materials and method" and "Discussion" sections of this study and the following article published in Lung Cancer: "CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians" by Ping Zhan, Jing Wang, Yu Zhang, Li-Xin Qiu, Su-feng Zhao, Qian Qian, Shu-Zhen Wei, Li-Ke Yu and Yong Song, Volume 69, 2010, pages 19-25...
July 2018: Journal of Cellular and Molecular Medicine
Blanka Halamoda-Kenzaoui, Uwe Holzwarth, Gert Roebben, Alessia Bogni, Susanne Bremer-Hoffmann
Appropriate documentary standards and reference materials are crucial building blocks for the development of innovative products. In order to support the emerging sector of nanomedicine, relevant standards must be identified and/or developed before the products will enter into the regulatory approval process. The anticipation of standardization needs requires a good understanding on the regulatory information requirements that can be triggered by the particularities of nanomedicines. However, robust datasets allowing firm conclusions on regulatory demands are not yet available due to a lack of regulatory experience with innovative products...
June 20, 2018: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
Renata Urban-Chmiel, Andrzej Wernicki, Jacek Wawrzykowski, Andrzej Puchalski, Anna Nowaczek, Marta Dec, Diana Stęgierska, Mohammed Mijbas Mohammed Alomari
The aim of study was to isolate, characterize and analyse the protein profiles of Myoviridae-like bacteriophages obtained from M. haemolytica using MALDI TOF mass spectrometry. The material consisted of the M. haemolytica reference strain ATCC® BAA410, reference serotypes A1, A2, A5, A6, A7, A9, and A11, and wild-type isolates of serotype A1. Bacteriophage morphology was examined with a transmission electron microscope. The proteins were separated in SDS-PAGE and two-dimensional electrophoresis and characterized by MALDI-TOF...
June 19, 2018: AMB Express
Tigst Demeke, Monika Eng
Droplet digital PCR (ddPCR) has been used for absolute quantification of genetically engineered (GE) events. Absolute quantification of GE events by duplex ddPCR requires the use of appropriate primers and probes for target and reference gene sequences in order to accurately determine the amount of GE materials. Single copy reference genes are generally preferred for absolute quantification of GE events by ddPCR. Study has not been conducted on a comparison of reference genes for absolute quantification of GE canola events by ddPCR...
May 2018: Biomolecular Detection and Quantification
Yingqi Wan, Lihan Chen
Crossmodal assimilation effect refers to the prominent phenomenon by which ensemble mean extracted from a sequence of task-irrelevant distractor events, such as auditory intervals, assimilates/biases the perception (such as visual interval) of the subsequent task-relevant target events in another sensory modality. In current experiments, using visual Ternus display, we examined the roles of temporal reference, materialized as the time information accumulated before the onset of target event, as well as the attentional modulation in crossmodal temporal interaction...
2018: Frontiers in Computational Neuroscience
Muhammad Awais Naeem, Andac Armutlulu, Qasim Imtiaz, Felix Donat, Robin Schäublin, Agnieszka Kierzkowska, Christoph R Müller
Calcium looping, a CO2 capture technique, may offer a mid-term if not near-term solution to mitigate climate change, triggered by the yet increasing anthropogenic CO2 emissions. A key requirement for the economic operation of calcium looping is the availability of highly effective CaO-based CO2 sorbents. Here we report a facile synthesis route that yields hollow, MgO-stabilized, CaO microspheres featuring highly porous multishelled morphologies. As a thermal stabilizer, MgO minimized the sintering-induced decay of the sorbents' CO2 capacity and ensured a stable CO2 uptake over multiple operation cycles...
June 19, 2018: Nature Communications
Leandro José de Assis, Mevlut Ulas, Laure Nicolas Annick Ries, Nadia Ali Mohamed El Ramli, Ozlem Sarikaya-Bayram, Gerhard H Braus, Ozgur Bayram, Gustavo Henrique Goldman
The attachment of one or more ubiquitin molecules by SCF (<u>S</u>kp-<u>C</u>ullin-<u>F</u>-box) complexes to protein substrates targets them for subsequent degradation by the 26S proteasome, allowing the control of numerous cellular processes. Glucose-mediated signaling and subsequent carbon catabolite repression (CCR) are processes relying on the functional regulation of target proteins, ultimately controlling the utilization of this carbon source. In the filamentous fungus Aspergillus nidulans , CCR is mediated by the transcription factor CreA, which modulates the expression of genes encoding biotechnologically relevant enzymes...
June 19, 2018: MBio
E Cunha, T T Lopez-Capp, R Inojosa, S R Marques, L O C Moraes, E Liberti, C E P Machado, L A S de Paiva, L Francesquini Júnior, E Daruge Junior, E Almeida Junior, E Soriano
This short communication aims to inform the scientific community of the existence of seven identified osteological collections in Brazil, most of which are housed in universities: 21st Century Collection of the Center for Studies in Forensic Anthropology, Recife; Identified Skeletal Collection of Sergipanos of the University Tiradentes, Aracaju; Identified Skull Collection of the State of Bahia, Aracaju; Osteological and Tomographic Collection - Prof. Dr. Eduardo Daruge, Piracicaba; Osteological Collection of the Institute of Teaching and Research in Forensic Sciences, Guarulhos; Identified Skull Collection of the Anatomy Museum Alfonso Bovero, São Paulo; and the Identified Skull Collection, São Paulo...
May 31, 2018: Forensic Science International
Timothy A Carey, David Sirett, Deborah Russell, John S Humphreys, John Wakerman
BACKGROUND: Visiting services address the problem of workforce deficit and access to effective primary health care services in isolated remote and rural locations. Little is known about their impact or effectiveness and thereby the extent to which they are helping to reduce the disparity in access and health outcomes between people living in remote areas compared with people living in urban regions of Australia. The objective of this study was to answer the question "What is the impact or effectiveness when different types of primary health care services visit, rather than reside in, rural and remote communities?" METHOD: We conducted a systematic review of peer-reviewed literature from established databases...
June 19, 2018: BMC Health Services Research
Andrea Koschinsky, Luise Heinrich, Klaus Boehnke, J Christopher Cohrs, Till Markus, Maor Shani, Pradeep Singh, Karen Smith Stegen, Welf Werner
Deep-sea mining refers to the retrieval of marine mineral resources such as manganese nodules, ferromanganese crusts and seafloor massive sulfide deposits, which contain a variety of metals that serve as crucial raw materials for a range of applications, from electronic devices to renewable energy technologies to construction materials. With the intent of decreasing dependence on imports, supporting the economy and potentially even overcoming the environmental problems related to conventional terrestrial mining, a number of public and private institutions have re-discovered their interest in exploring the prospects of deep-sea mining, which had been deemed economically and technically unfeasible in the early 1980 s...
June 19, 2018: Integrated Environmental Assessment and Management
Xiao Zhang, Wei Tan, Fiona Smail, Michael De Volder, Norman Fleck, Adam Boies
Some assemblies of nanomaterials, like carbon nanotube (CNT) sheet or film, always show outstanding and anisotropic thermal properties. However, there is still a lack of comprehensive thermal conductivity (κ) characterizations on CNT sheets, as well as lack of estimations of their true contributions on thermal enhancement of polymer composites when used as additives. Always, these characterizations were hindered by the low heat capacity, anisotropic thermal properties or low electrical conductivity of assemblies and their nanocomposites...
June 19, 2018: Nanotechnology
Katharina Brehmer, Torkel B Brismar, Fabian Morsbach, Anders Svensson, Per Stål, Antonios Tzortzakakis, Nikolaos Voulgarakis, Michael A Fischer
Purpose To develop and evaluate a triple arterial phase CT liver protocol with a similar radiation dose to that of standard single arterial phase CT in study subjects suspected of having hepatocellular carcinoma (HCC). Materials and Methods The study consisted of a retrospective part A for protocol development (n = 15) and a prospective part B to evaluate diagnostic accuracy (n = 38). All 53 participants underwent perfusion CT with 50 mL contrast material between August 2013 and September 2014. Group B underwent an additional standard multiphasic liver CT examination with 120 mL of contrast material (range, 70-143 mL)...
June 19, 2018: Radiology
Reza Saberi, Vahideh Moin-Vaziri, Homa Hajjaran, Maryam Niyyati, Niloofar Taghipour, Farnaz Kheirandish, Alireza Abadi
Background & objectives: Ilam province is one of the oldest known endemic foci of zoonotic cutaneous leishmani- asis (CL) in Iran; and the recent studies have shown an increasing trend in the number of cases from the region. This study was aimed to investigate the parasite species and genetic diversity of isolates obtained from CL patients based on the N-acetylglucosamine-1-phosphate transferase (nagt) gene. Methods: Exudate materials were collected from the swollen margin of the skin lesions of the patients suspected with CL who were referred to health centers laboratory of Mehran, Dehloran, Ilam and Malekshahi cities in the Ilam province...
January 2018: Journal of Vector Borne Diseases
Manuel Contreras Llanes, Manuel Jesús Gázquez González, Silvia María Pérez Moreno, Juan Pedro Bolívar Raya
This work is focused on the manufacture of commercial cement using as additive ilmenite mud, a waste generated during TiO2 pigment production. The cements were produced by adding different proportions of mud (2.5, 5 and 10 wt%) to ordinary Portland cement (OPC). The ilmenite mud and the ilmenite mud cements (IMCs) were characterised physico-chemically by X-ray fluorescence (XRF), inductively coupled plasma mass spectrometry (ICP-MS) and X-ray diffraction (XRD). Moreover, the technological properties of the IMCs were evaluated and compared with a reference material (OPC)...
June 19, 2018: Environmental Science and Pollution Research International
Fleur T van Beek, Rob Edam, Bob W J Pirok, Wim J L Genuit, Peter J Schoenmakers
Heavy oil refers to the part of crude oil that is not amenable to further distillation. Processing of these materials to useful products provides added value, but requires advanced technology as well as extensive characterization in order to optimize the yield of the most profitable products. The use of comprehensive two-dimensional liquid chromatography (LC × LC) was investigated for the characterization of de-asphalted short residue, also called maltenes. Initial studies were performed on a polycyclic aromatic hydrocarbon standard, an aromatic extract of hydrowax, and the fractions obtained after solvent fractionation of the maltenes...
June 5, 2018: Journal of Chromatography. A
María Eugenia Parron-Rubio, Francisca Perez-García, Antonio Gonzalez-Herrera, María Dolores Rubio-Cintas
Concrete consumption greatly exceeds the use of any other material in engineering. This is due to its good properties as a construction material and the availability of its components. Nevertheless, the present worldwide construction increases and the high-energy consumption for cement production means a high environmental impact. On the other hand, one of the main problems in the iron and steel industry is waste generation and byproducts that must be properly processed or reused to promote environmental sustainability...
June 17, 2018: Materials
Antonio Scarano, Felice Lorusso, Merla Arcangelo, Camillo D'Arcangelo, Renato Celletti, Pablo Santos de Oliveira
Purpose: Post-operative pain and swelling are frequently observed after sinus lift procedures. The aim of the present study was the clinical evaluation of swelling and pain of two different sinus flap lift techniques using a visual analogue scale (VAS), verbal rating scale (VRS), and infrared thermal imaging (i.e., thermography). Materials Methods : A randomized controlled trial was conducted with 15 patients (30 sinuses in total) randomly allocated into two groups. For the sinuses of Group I a trapezoidal flap was used, while for Group II a modified triangular flap without anterior release was utilized...
June 16, 2018: International Journal of Environmental Research and Public Health
Elsebeth Stenager, Erik Christiansen, Gitte Handberg, Børge Jensen
Background There are several studies about the relationship between depression and chronic non-malignant pain. These studies have shown that up to 50% of chronic pain patients are suffering from depression. It is, therefore, reasonable to expect that pain patients would also have an increased risk of suicidal behaviour. This problem is not well studied. Since 1990 the Centre for Suicide Research, Odense, Denmark has registered all suicide attempts in patients residing in the Region of Funen, Denmark. The Pain Clinic, Odense University Hospital receives patients with chronic pain from the entire Region of Southern Denmark...
December 29, 2017: Scandinavian Journal of Pain
Samaa Al Sayegh, Tove Filén, Mats Johansson, Susanne Sandström, Gisela Stiewe, Stephen Butler
Background and purpose This case of a 42 year old woman with lower extremity Complex Regional Pain Syndrome (CRPS) after a twisting injury of the ankle, effectively treated with the addition of mirror therapy to a rehabilitation programme, prompted a literature review of both CRPS and mirror therapy. Mirror therapy is a newer adjunct to other forms of pain control and functional restoration for treatment of CRPS as well as other difficult clinical problems. This was a required group project as part of a university based course in chronic pain for healthcare workers...
December 29, 2017: Scandinavian Journal of Pain
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