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https://www.readbyqxmd.com/read/28640793/intraoperative-computed-tomography-ct-for-treating-giant-carotid-intracavernous-aneurysms
#1
Zhe Xue, Fuyu Wang, Zhenghui Sun, Hui Zhang, Chen Wu, Dongsheng Kong, Bainan Xu
BACKGROUND Giant carotid intracavernous aneurysm refers to those lesions larger than 2.5 cm and derived from a cavernous segment, accounting for about 30% of all intracranial tumors. Dynamic CT perfusion imaging (PCT) is a common method recently employed to evaluate cerebral perfusion. This study investigated the efficacy and clinical application of intraoperative CT in the surgery for giant symptomatic carotid intracavernous aneurysm. MATERIAL AND METHODS A retrospective analysis was performed on 23 cases with giant symptomatic carotid intracavernous aneurysm...
June 22, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28640750/in-vivo-monitoring-of-infection-via-implantable-microsensors-a-pilot-study
#2
Andrej Ring, Heiko Sorg, Andreas Weltin, Daniel J Tilkorn, Jochen Kieninger, Gerald Urban, Jörg Hauser
The most common complication after implantation of foreign material is infection, leading to implant failure and severe patient discomfort. Smoldering-infections proceed inapparently and might not get verified by radiological diagnostics. Early identification of this type of infection might significantly reduce the rate of complications. Therefore, we manufactured a microsensor strip in a hybrid of thin-film and laminate technology in a wafer-level process. It comprises electrochemical, amperometric microsensors for glucose, oxygen and lactate as well as an integrated reference electrode...
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28640694/assessment-of-rectal-tumors-with-shear-wave-elastography-before-surgery-comparison-with-endorectal-us
#3
Li-Da Chen, Wei Wang, Jian-Bo Xu, Jian-Hui Chen, Xin-Hua Zhang, Hui Wu, Jin-Ning Ye, Jin-Ya Liu, Zhi-Qiang Nie, Ming-De Lu, Xiao-Yan Xie
Purpose To compare the value of endorectal ultrasonography (US) with shear-wave elastography (SWE) in staging rectal tumors before surgery. Materials and Methods This prospective study was approved by the institutional review board and written informed consent was obtained. In a pilot cohort from April 2015 to January 2016, 70 patients with rectal adenocarcinomas and/or adenomas confirmed with histopathologic examination underwent both endorectal US and SWE. Tumor stiffness and three regions of reference backgrounds, as well as tumor stiffness ratios (SRs) versus these backgrounds, were analyzed...
June 21, 2017: Radiology
https://www.readbyqxmd.com/read/28640693/evaluation-of-screening-us-detected-breast-masses-by-combined-use-of-elastography-and-color-doppler-us-with-b-mode-us-in-women-with-dense-breasts-a-multicenter-prospective-study
#4
Su Hyun Lee, Jin Chung, Hye Young Choi, Seon Hyeong Choi, Eun Bi Ryu, Kyung Hee Ko, Hye Ryoung Koo, Jeong Seon Park, Ann Yi, Ji Hyun Youk, Eun Ju Son, A Jung Chu, Jung Min Chang, Nariya Cho, Myoung-Jin Jang, Shin Ho Kook, Eun Suk Cha, Woo Kyung Moon
Purpose To investigate the value of the combined use of elastography and color Doppler ultrasonography (US) with B-mode US for evaluation of screening US-detected breast masses in women with dense breasts. Materials and Methods This prospective, multicenter study included asymptomatic women with dense breasts who were referred for screening US between November 2013 and December 2014. Eligible women had a newly detected breast mass at conventional B-mode US screening, for which elastography and color Doppler US were performed...
June 21, 2017: Radiology
https://www.readbyqxmd.com/read/28636805/a-hybrid-phantom-system-for-patient-skin-and-organ-dosimetry-in-fluoroscopically-guided-interventions
#5
David Borrego, Daniel Siragusa, Stephen Balter, Wesley E Bolch
To investigate calibrations for improved estimates of skin dose and to develop software for computing absorbed organ doses for fluoroscopically guided interventions (FGIs) with the use of radiation dose structured reports (RDSR) and the UF/NCI family of hybrid computational phantoms METHODS AND MATERIALS: Institutional review board approval was obtained for this retrospective study in which ten RDSRs were selected for their high cumulative reference air kerma values. Skin doses were computed using the University of Florida's rapid in-clinic peak skin dose algorithm (or UF-RIPSA)...
June 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28635869/-the-topical-problems-of-expert-mistakes-and-evaluation-of-the-quality-of-forensic-medical-expertises-based-on-the-analysis-of-the-reports-published-in-the-journal-sudebno-meditsinskaya-ekspertiza-forensic-medical-expertise-during-the-period-from-1958-till
#6
L A Shmarov
The objective of the present study was the thematic analysis of the reports published in the journal 'Sudebno-meditsinskaya ekspertiza' (Forensic Medical Expertise) during the period from 1958 till 2015 that contain the authors' characteristics of the mistakes made in connection with the performance of various forms of forensic medical expertise with special reference to their quality and time schedules. A total of 268 issues of the journal were looked through from which 25 articles were selected dealing with the analysis of expert mistakes...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28635631/ag-nanoparticles-drop-casting-modification-of-screen-printed-electrodes-for-the-simultaneous-voltammetric-determination-of-cu-ii-and-pb-ii
#7
Clara Pérez-Ràfols, Julio Bastos-Arrieta, Núria Serrano, José Manuel Díaz-Cruz, Cristina Ariño, Joan de Pablo, Miquel Esteban
A new silver nanoparticle modified screen-printed electrode was developed and applied to the simultaneous determination of Pb(II) and Cu(II). Two different types of silver nanoparticles with different shapes and sizes, Ag nanoseeds and Ag nanoprisms, were microscopically characterized and three different carbon substrates, graphite, graphene and carbon nanofibers, were tested. The best analytical performance was achieved for the combination of Ag nanoseeds with a carbon nanofiber modified screen-printed electrode...
June 21, 2017: Sensors
https://www.readbyqxmd.com/read/28635177/engineering-human-bone-grafts-with-new-macroporous-calcium-phosphate-cement-scaffolds
#8
Martina Sladkova, Michael Palmer, Caroline Öhman, Jiayi Cheng, Shoug Al-Ansari, Munerah Saad, Håkan Engqvist, Giuseppe Maria de Peppo
Bone engineering opens the possibility to grow large amounts of tissue products by combining patient-specific cells with compliant biomaterials. Decellularized tissue matrices represent suitable biomaterials but availability, long processing time, excessive cost, and concerns on pathogen transmission have led to the development of biomimetic synthetic alternatives. We recently fabricated calcium phosphate cement (CPC) scaffolds with variable macroporosity using a facile synthesis method with minimal manufacturing steps, and demonstrated long-term biocompatibility in vitro...
June 21, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28635171/replacing-paps-in-vitro-phase-ii-sulfation-of-steroids-with-the-liver-s9-fraction-employing-atp-and-sodium-sulfate
#9
Sumudu A Weththasinghe, Christopher C Waller, Han Ling Fam, Bradley J Stevenson, Adam T Cawley, Malcolm D McLeod
In vitro technologies provide the capacity to study drug metabolism where in vivo studies are precluded due to ethical or financial constraints. The metabolites generated by in vitro studies can assist anti-doping laboratories to develop protocols for the detection of novel substances that would otherwise evade routine screening efforts. In addition, professional bodies such as the Association of Official Racing Chemists (AORC) currently permit the use of in vitro derived reference materials for confirmation purposes providing additional impetus for the development of cost effective in vitro metabolism platforms...
June 21, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28635135/the-gene-expression-landscape-of-pine-seedling-tissues
#10
Rafael A Cañas, Zhen Li, M Belén Pascual, Vanessa Castro-Rodríguez, Concepción Ávila, Lieven Sterck, Yves Van de Peer, Francisco M Cánovas
Conifers dominate vast regions of the Northern hemisphere. They are the main source of raw materials for timber industry as well as a wide range of biomaterials. Despite their inherent difficulties as experimental models for classical plant biology research, the technological advances in genomics research are enabling fundamental studies on these plants. The use of laser capture microdissection followed by transcriptomic analysis is a powerful tool for unravelling the molecular and functional organization of conifer tissues and specialized cells...
June 21, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28634759/current-applications-of-high-resolution-mass-spectrometry-for-the-analysis-of-new-psychoactive-substances-a-critical-review
#11
REVIEW
Daniel Pasin, Adam Cawley, Sergei Bidny, Shanlin Fu
The proliferation of new psychoactive substances (NPS) in recent years has resulted in the development of numerous analytical methods for the detection and identification of known and unknown NPS derivatives. High-resolution mass spectrometry (HRMS) has been identified as the method of choice for broad screening of NPS in a wide range of analytical contexts because of its ability to measure accurate masses using data-independent acquisition (DIA) techniques. Additionally, it has shown promise for non-targeted screening strategies that have been developed in order to detect and identify novel analogues without the need for certified reference materials (CRMs) or comprehensive mass spectral libraries...
June 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28633591/approaches-in-topical-ocular-drug-delivery-and-developments-in-the-use-of-contact-lenses-as-drug-delivery-devices
#12
Prina Mehta, Rita Haj-Ahmad, Ali Al-Kinani, Muhammad Sohail Arshad, Ming-Wei Chang, Raid G Alany, Zeeshan Ahmad
Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies, smart polymeric systems and multimodal functionalities. The intended target for specific treatment of disease is the key defining developing parameter. One such area which has undergone significant advancements relates to ocular delivery. This has been expedited by the development of material advancement, mechanistic concepts and through the deployment of advanced process technologies. This review will focus on the developments within lens-based drug delivery while touching on conventional and current methods of topical ocular drug delivery...
July 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28632826/-pyogenic-liver-abscess-in-children-clinical-experience-in-a-pediatric-reference-center
#13
Carolina Carballo, Claudia Cazes, Mariana Matsuda, M Laura Praino, Noemí Rivas, Eduardo López
INTRODUCTION: Liver abscess is a serious and an uncommon pediatric disease. OBJECTIVE AND METHOD: Description of 20 pediatric patients with liver abscess admitted in "Ricardo Gutierrez" Children's Hospital, a Tertiary Reference Center of Buenos Aires, between 2009 and 2015. RESULTS: The hospitalization rate was 35/100.000 admissions. Median age was 5 years old, male/female ratio 4/1. Five patients (25%) had predisposing factors. Median days at diagnosis were 12...
April 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28632499/model-based-sphere-localization-mbsl-in-x-ray-projections
#14
Stefan Sawall, Joscha Maier, Carsten Leinweber, David Prox, Carsten Funck, Jan Kuntz, Marc Kachelriess
The detection of spherical markers in x-ray projections is an important task in a variety of applications, e.g. geometric calibration and detector distortion correction. Therein, the projection of the sphere center on the detector is of particular interest as the used spherical beads are no ideal point-like objects. Only few methods have been proposed to estimate this respective position on the detector with sufficient accuracy and surrogate positions, e.g. the center of gravity, are used, impairing the results of subsequent algorithms...
June 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28632488/vector-borne-pathogens-in-stray-dogs-in-northeastern-turkey
#15
Esin Guven, Hamza Avcioglu, Seyda Cengiz, Armagan Hayirli
This experiment was carried out to attain prevalence and molecular characterization of pathogens causing canine vector-borne diseases (CVBDs) including babesiosis, hepatozoonosis, leishmaniasis, filariosis (Dirofilaria immitis, Dirofilaria repens, and Acanthocheilonema reconditum), ehrlichiosis (Ehrlichia canis), and anaplasmosis (Anaplasma platys) in stray dogs. The study material consisted of 133 asymptomatic female (n = 96) and male (n = 37) stray dogs (≤1 year old, n = 16 and 1-6 years old, n = 117) housed in the Animal Care and Rehabilitation Center, Erzurum, Northeastern Turkey...
June 20, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28629531/survey-of-traditional-dai-medicine-reveals-species-confusion-and-potential-safety-concerns-a-case-study-on-radix-clerodendri-japonicum
#16
Bao-Zhong Duan, Hai-Lan Fang, Xi-Wen Li, Lin-Fang Huang, Wang Ping, Shi-Lin Chen
The adulteration of herbal products is a threat to consumer safety. In the present study, we surveyed the species composition of commercial Radix Clerodendri Japonicum products using DNA barcoding as a supervisory method. A reference database for plant-material DNA-barcode was successfully constructed with 48 voucher samples from 12 Clerodendrum species. The database was used to identify 27 Radix Clerodendri Japonicum decoction piece samples purchased from drug stores and hospitals. The DNA sequencing results revealed that only 1 decoction piece (3...
June 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28629097/emerging-bone-tissue-engineering-via-polyhydroxyalkanoate-pha-based-scaffolds
#17
REVIEW
Janice Lim, Mingliang You, Jian Li, Zibiao Li
Polyhydroxyalkanoates (PHAs) are a class of biodegradable polymers derived from microorganisms. On top of their biodegradability and biocompatibility, different PHA types can contribute to varying mechanical and chemical properties. This has led to increasing attention to the use of PHAs in numerous biomedical applications over the past few decades. Bone tissue engineering refers to the regeneration of new bone through providing mechanical support while inducing cell growth on the PHA scaffolds having a porous structure for tissue regeneration...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28628887/determining-concentrations-of-elements-with-different-reaction-channels-in-photon-activation
#18
Z J Sun, K Okafor, S Isa
In photon activation, same element may be activated by the bremsstrahlung beam through different nuclear reaction channels and produce different radioisotopes. These radioisotopes follow their own decay schemes and generate characteristic gamma rays. This phenomenon usually is an interference in spectra analysis, but it also offers a theoretical feasibility to determine the concentration of one element through different reaction channels. To realize this theoretical feasibility, we conducted series of photon activation experiments with sample and reference of known concentrations...
June 13, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28628420/value-of-multiparametric-us-in-the-assessment-of-intratesticular-lesions
#19
Thomas Auer, Tobias De Zordo, Christian Dejaco, Leonhard Gruber, Renate Pichler, Werner Jaschke, Vikram S Dogra, Friedrich Aigner
Purpose To evaluate the diagnostic accuracy of multiparametric ultrasonography (US) consisting of gray-scale US, color Doppler US, strain elastography, and contrast agent-enhanced US in the assessment of intratesticular lesions. Materials and Methods Institutional review board approval was obtained for this retrospective study. From January 2012 to December 2015, 55 focal testicular lesions that were indeterminate on gray-scale US scans were further characterized with color Doppler US, strain elastography, and contrast-enhanced US...
June 16, 2017: Radiology
https://www.readbyqxmd.com/read/28626487/identification-of-the-chemical-constituents-in-simiao-wan-and-rat-plasma-after-oral-administration-by-gc-ms-and-lc-ms
#20
Yunshuang Fan, Yamei Li, Yuanyuan Wu, Lixin Li, Yuming Wang, Yubo Li
Simiao Wan (SMW), an important multiherbal formula used in traditional Chinese medicine, is extensively used to treat rheumatoid arthritis. However, the knowledge of the bioactive components of SMW remains unclear. Thus, gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were used to analyze the chemical constituents of volatile and nonvolatile extracts of SMW, as well as its absorbed components in rat plasma after oral SMW administration. Identification of several compounds was enabled by comparison of retention times, MS spectra, and MS/MS spectral data with the standard substance and reference materials reported in the literature...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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