Read by QxMD icon Read

Delayed graft function meta

Angelo Territo, Alex Mottrie, Ronney Abaza, Craig Rogers, Mani Menon, Mahendra Bhandari, Rajesh Ahlawat, Alberto Breda
INTRODUCTION: For the treatment of patients with end-stage renal disease, kidney transplantation is preferred to renal replacement modalities such as hemodialysis and peritoneal dialysis. Although open surgery remains the gold standard, minimally invasive approaches have recently been applied in transplant kidney surgery. Despite growing enthusiasm and potential benefits of robotic kidney transplant, many aspects of this novel technique remain controversial. Aim of this study was to analyze the current status and future developments in robotic-assisted surgery for kidney transplantation...
November 30, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Ahmer M Hameed, Henry C Pleass, Germaine Wong, Wayne J Hawthorne
BACKGROUND: The two main options for renal allograft preservation are static cold storage (CS) and machine perfusion (MP). There has been considerably increased interest in MP preservation of kidneys, however conflicting evidence regarding its efficacy and associated costs have impacted its scale of clinical uptake. Additionally, there is no clear consensus regarding oxygenation, and hypo- or normothermia, in conjunction with MP, and its mechanisms of action are also debated. The primary aims of this article were to elucidate the benefits of MP preservation with and without oxygenation, and/or under normothermic conditions, when compared with CS prior to deceased donor kidney transplantation...
October 2016: Medicine (Baltimore)
X Du, W Wang, Z-J Sun, L L Su, X-D Zhang
BACKGROUND: The aim of this study was to evaluate the effects of a single high dose of the anti-T-lymphocyte globulin Fresenius (ATG-F), given before kidney transplantation, on the prevention of acute rejection response and infections and on the survival rate of the renal graft and patient. METHODS: Databases including PubMed, Embase, and the Cochrane Library were searched to identify randomized controlled trials relevant to studying the presurgical use of a single high dose of ATG-F...
July 2016: Transplantation Proceedings
Marcel Zorgdrager, Christina Krikke, Sybrand H Hofker, Henri G D Leuvenink, Robert A Pol
BACKGROUND: The use of grafts with multiple renal arteries (MRA) in renal transplantation has not been clearly established. MATERIAL/METHODS: A systematic literature review used predefined terms to search PubMed, EMBASE, and the Cochrane Library for all studies since 1985 that included more than 50 MRA grafts. A total of 23 studies, comprising a total of 18,289 patients, were eligible to be included in the meta-analysis. RESULTS: Patients who received an MRA graft compared to single renal artery (SRA) grafts showed significantly higher complication rates (13...
2016: Annals of Transplantation: Quarterly of the Polish Transplantation Society
Maozhi Tang, Tianyi Li, Hong Liu
BACKGROUND: Peritoneal dialysis (PD) and hemodialysis (HD) have been considered the 2 standard pre-transplant dialysis modalities in patients awaiting kidney transplantation. However, the impact of pretransplant dialysis on the short- and long-term post-transplant outcomes remains controversial. METHODS: We searched PubMed, EMBASE and the Cochrane central register of controlled trials for this review. Twelve studies were identified by strict screening for the meta-analysis...
2016: Blood Purification
Reza Gholamnezhadjafari, Reza Falak, Nader Tajik, Reza Aflatoonian, Abbas Ali Keshtkar, Abbas Rezaei
INTRODUCTION: Studies have shown that FTY720 has inconsistent effects in kidney transplant recipients. Several review articles on FTY720 have been published, but most have focused on the mechanism of action of FTY720. Therefore, this review aims to evaluate and determine the beneficial and harmful effects of FTY720 therapy in kidney transplant recipients. METHODS AND ANALYSIS: We electronically searched the following databases: PubMed, Scopus, the Web of Sciences, EMBASE, Cochrane databases and the Cochrane Central Registry of Controlled Trials...
2016: BMJ Open
Bulang He, Alexandra Bremner, Ying Han, Jeffrey M Hamdorf
OBJECTIVES: Laparoscopic living-donor nephrectomy is now widely used because of its many beneficial features. Currently, there are 2 major techniques: the laparoscopic intraperitoneal approach and the retroperitoneoscopic approach. There is no evidence to support one particular approach over another. Therefore, in this study, we conducted a systematic literature review with the aim of defining which technique is superior. MATERIALS AND METHODS: The Embase, PubMed, and Cochrane literature databases were searched for English language articles published between January 1994 and January 2013 using the terms "laparoscopic donor nephrectomy," "retroperitoneoscopic donor nephrectomy," and "live donor nephrectomy...
April 2016: Experimental and Clinical Transplantation
Anshuman Sood, David N Hakim, Nadey S Hakim
OBJECTIVES: The prevalence of obesity is increasing rapidly and globally, yet systemic reviews on this topic are scarce. Our meta-analysis and systemic review aimed to assess how obesity affects 5 postoperative outcomes: biopsy-proven acute rejection, patient death, allograft loss, type 2 diabetes mellitus after transplant, and delayed graft function. MATERIALS AND METHODS: We evaluated peer-reviewed literature from 22 medical databases. Studies were included if they were conducted in accordance with the Meta-analysis of Observational Studies in Epidemiology criteria, only examined postoperative outcomes in adult patients, only examined the relation between recipient obesity at time of transplant and our 5 postoperative outcomes, and had a minimum score of > 5 stars on the Newcastle-Ottawa scale for nonrandomized studies...
April 2016: Experimental and Clinical Transplantation
Alexander Decruyenaere, Philippe Decruyenaere, Patrick Peeters, Frank Vermassen
BACKGROUND Kidney transplantation is the preferred treatment for patients with end-stage renal disease. Delayed graft function (DGF) is a common complication and is associated with short- and long-term outcomes. Several predictive models for DGF have been developed. MATERIAL AND METHODS 497 kidney transplantations from deceased donors at our center between 2005-2011 are included. Firstly, the predictive accuracy of the existing models proposed by Irish et al. (M1), Jeldres et al. (M2), Chapal et al. (M3), and Zaza et al...
2015: Annals of Transplantation: Quarterly of the Polish Transplantation Society
Kun Wang, Peijin Zhang, Xianlin Xu, Min Fan
OBJECTIVES: We assessed the safety and efficacy of right versus left laparoscopic living-donor nephrectomy. Few clinical controlled studies have compared the right and left side, and most trials have a small sample number and varied results. A meta-analysis of published trials was performed to determine the effects of the 2 different approaches. MATERIALS AND METHODS: Major databases including Medline (PubMed), Embase, Ovid, and Cochrane were searched to identify studies comparing right and left laparoscopic living-donor nephrectomy (January 2000 to January 2014)...
June 2015: Experimental and Clinical Transplantation
Christopher J Hill, Aisling E Courtney, Christopher R Cardwell, Alexander P Maxwell, Giuseppe Lucarelli, Massimiliano Veroux, Frederico Furriel, Robert M Cannon, Ellen K Hoogeveen, Mona Doshi, Jennifer A McCaughan
BACKGROUND: The prevalence of obesity is increasing globally and is associated with chronic kidney disease and premature mortality. However, the impact of recipient obesity on kidney transplant outcomes remains unclear. This study aimed to investigate the association between recipient obesity and mortality, death-censored graft loss and delayed graft function (DGF) following kidney transplantation. METHODS: A systematic review and meta-analysis was conducted using Medline, Embase and the Cochrane Library...
August 2015: Nephrology, Dialysis, Transplantation
Jeffrey A Lafranca, Jan N M IJermans, Michiel G H Betjes, Frank J M F Dor
BACKGROUND: Whether overweight or obese end stage renal disease (ESRD) patients are suitable for renal transplantation (RT) is often debated. The objective of this review and meta-analysis was to systematically investigate the outcome of low versus high BMI recipients after RT. METHODS: Comprehensive searches were conducted in MEDLINE OvidSP, Web of Science, Google Scholar, Embase, and CENTRAL (the Cochrane Library 2014, issue 8). We reviewed four major guidelines that are available regarding (potential) RT recipients...
2015: BMC Medicine
John Hardman, Jameel Muzaffar, Paul Nankivell, Chris Coulson
OBJECTIVE: To study the effectiveness of Type 1 tympanoplasty for chronic tympanic membrane perforations in the pediatric age group and to investigate factors influencing its success. DATA SOURCES: Searches were conducted of the MEDLINE database and the Cochrane Database of Systematic Reviews using terms focused around tympanoplasty and children. Searches were performed on June 23, 2014 and limited to English language entries since January 1, 1997. STUDY SELECTION: Studies reporting tympanoplasty closure rates in children 18 years and younger, with a minimum follow-up of 6 months, were included...
June 2015: Otology & Neurotology
Hui Xin, Yu-Zheng Ge, Ran Wu, Qian Yin, Liu-Hua Zhou, Jiang-Wei Shen, Tian-Ze Lu, Zhi-Kai Hu, Min Wang, Chang-Cheng Zhou, Jian-Ping Wu, Wen-Cheng Li, Jia-Geng Zhu, Rui-Peng Jia
PURPOSE: Current evidence suggests that preconditioning with erythropoietin (EPO) can protect against ischemia reperfusion injury in rodents. However, randomized controlled trials (RCTs) assessing the efficacy and safety of high-dose EPO in kidney transplantation have yielded inconclusive results. Herein, we performed a meta-analysis of RCTs to assess whether the administration of high-dose EPO can improve graft function and the potential adverse events. METHODS: Relevant RCT studies that investigated high-dose EPO on graft function after kidney transplantation were comprehensively searched in Pubmed, Embase, and Cochrane Library until July 10, 2014...
February 2015: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Beatrice Coupes, Declan G de Freitas, Stephen A Roberts, Ian Read, Hany Riad, Paul E C Brenchley, Michael L Picton
BACKGROUND: Extended criteria donor (ECD) and donation after circulatory death (DCD) kidneys are at increased risk of delayed graft function (DGF). Experimental evidence suggests that erythropoietin (EPO) attenuates renal damage in acute kidney injury. This study piloted the administration of high dose recombinant human EPO-beta at implantation of ECD and DCD kidneys, and evaluated biomarkers of kidney injury post-transplant. METHODS: Forty patients were randomly assigned to receive either rhEPO-b (100,000 iu) (n = 19 in the intervention group, as 1 patient was un-transplantable post randomisation), or placebo (n = 20) in this, double blind, placebo-controlled trial at Manchester Royal Infirmary from August 2007 to June 2009...
February 3, 2015: BMC Research Notes
Georgios Vlachopanos, Theodoros I Kassimatis, Athanasios Agrafiotis
Delayed graft function (DGF) due to ischemia-reperfusion injury is a major early complication of kidney transplantation (KT). Recombinant human erythropoietin (rHuEPO) has been shown to exert nephroprotective action in animal models. We conducted a meta-analysis to explore the impact of rHuEPO on DGF in KT. Eligible studies comparing perioperative high-dose rHuEPO with placebo or no therapy for prevention of DGF were identified through MEDLINE, CENTRAL, and Transplant Library. Their design and data were assessed by two independent reviewers...
March 2015: Transplant International: Official Journal of the European Society for Organ Transplantation
Yingzi Ming, Mingjie Shao, Tingting Tian, Xingguo She, Hong Liu, Shaojun Ye, Qifa Ye
BACKGROUND: Our goal was to evaluate the outcomes of kidney transplants from controlled cardiac death donors compared with brain death donors by conducting a meta-analysis of cohort studies. METHODS: The PubMed database and EMBASE were searched from January 1980 to July 2013 to identify studies that met pre-stated inclusion criteria. Reference lists of retrieved articles were also reviewed. Two authors independently extracted information on the designs of the studies, the characteristics of the study participants, and outcome assessments...
2014: Chinese Medical Journal
Marta Nedbálková, Jan Svojanovský, Karel Trnavský, Milan Kuman, Jiří Jarkovský, Michal Karpíšek, Miroslav Souček
INTRODUCTION: Metabolic syndrome is a risk factor for cardiovascular diseases. Higher risk of the metabolic syndrome and its components in patients after kidney transplantation is caused by immunosuppressive therapy. THE AIM OF OUR STUDY was to evaluate the prevalence of the metabolic syndrome and its components in kidney transplant recipients and to analyse their influence on allograft function and albuminuria. PATIENTS, METHOD AND RESULTS: In the study we monitored 69 patients after cadaveric kidney transplantation...
March 2014: Vnitr̆ní Lékar̆ství
Massimo Del Fabbro, Valentina Ceresoli
AIMS: The use of tilted implants has recently gained popularity as a feasible option for the treatment of edentulous jaws by means of implant-supported rehabilitations without recurring to grafting procedures. The aim of this review was to compare the crestal bone level change around axially placed vs. tilted implants supporting fixed prosthetic reconstructions for the rehabilitation of partially and fully edentulous jaws, after at least 1 year of function. MATERIALS AND METHODS: An electronic search of databases plus a hand search on the most relevant journals up to January 2014 was performed...
2014: European Journal of Oral Implantology
Bruna B Nicoletto, Natasha K O Fonseca, Roberto C Manfro, Luiz Felipe S Gonçalves, Cristiane Bauermann Leitão, Gabriela C Souza
BACKGROUND: The effects of obesity on outcomes reported after kidney transplantation have been controversial. The purpose of this systematic review and meta-analysis was to elucidate this issue. METHODS: MEDLINE, EMBASE, Cochrane Library, and gray literature were searched up to August 6, 2013. Studies that compared obese and nonobese patients who underwent kidney transplantation and evaluated one of these outcomes-delayed graft function (DGF), acute rejection, graft or patient survival at 1 or 5 years after transplantation, or death by cardiovascular disease (CVD)-were included...
July 27, 2014: Transplantation
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"