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https://www.readbyqxmd.com/read/29142969/elucidation-of-renal-scars-in-children-with%C3%A2-vesicoureteral-reflux-using-contrast-enhanced-ultrasound-a-pilot%C3%A2-study
#1
David S Hains, Harris L Cohen, M Beth McCarville, Ellen E Ellison, Amy Huffman, Stacey Glass, Aslam H Qureshi, Keith R Pierce, Ashlyn L Cahill, Ashley Dixon, Noel Delos Santos
Introduction: Vesicoureteral reflux is a common disorder in children but can result in kidney scarring following acute pyelonephritis. The gold standard diagnostic to detect renal scars in children is (99m)Tc-dimercaptosuccinic acid (DMSA) scintigraphy. DMSA has a number of limitations including radiation exposure, need for sedation, and radiotracer supply shortages. Contrast-enhanced ultrasound (CEUS) is a technique whereby biocompatible microspheres of inert gas are administered i.v...
May 2017: KI Reports
https://www.readbyqxmd.com/read/29142190/detection-of-atherosclerotic-plaques-in-the-rabbit-aorta-using-ultrasound-microbubbles-conjugated-to-interleukin-18-antibodies
#2
Zhen-Zhen Jiang, Xia-Tian Liu, Cai-Ye Ma, Cong He, Xing-Yun Li, Chuan-Lin Hou, Zu-Sheng Cheng, Guo-Yuan Xia
BACKGROUND The purpose of the study was to investigate the ability of microbubbles (MBs) targeting interleukin-18 (IL-18) to detect plaques in a rabbit atherosclerotic plaque model. MATERIAL AND METHODS A rabbit atherosclerotic plaque model was established. The locations of the atherosclerotic plaques were verified by two-dimensional scanning and color Doppler flow imaging. An IL-18 antibody was conjugated to naked MBs (MBc) using the biotin-streptavidin conjugation method, resulting in the formation of MBIL-18...
November 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29138385/parameters-for-contrast-enhanced-ultrasound-ceus-of-enlarged-superficial-lymph-nodes-for-the-evaluation-of-therapeutic-response-in-lymphoma-a-preliminary-study
#3
Lei Xin, Zhimei Yan, Xiaojuan Zhang, Yichen Zang, Zhaoyan Ding, Hongwei Xue, Cheng Zhao
BACKGROUND The aims of this preliminary study were to evaluate contrast-enhanced ultrasound (CEUS) imaging and the therapeutic response of enlarged superficial lymph nodes in patients with lymphoma before and after chemotherapy and to determine the most useful CEUS response parameters. MATERIAL AND METHODS Forty-three patients with lymphoma, with 43 enlarged superficial lymph nodes, underwent CEUS and conventional ultrasound (US), before treatment and after the first three cycles of chemotherapy. Clinical responses included overall response (OR) and no response (NR)...
November 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29137375/impact-of-tumor-size-and-cirrhotic-background-for-differentiating-hcc-and-icc-with-ceus-does-it-matter-for-patients-undergoing-hepatectomy
#4
Chen Jin, Xiao-Yun Zhang, Jia-Wu Li, Chuan Li, Wei Peng, Tian-Fu Wen, Yan Luo, Qiang Lu, Xiao-Fei Zhong, Jing-Yi Zhang, Lv-Nan Yan, Jia-Yin Yang
Objectives: The aim of this study was to investigate the role of contrast-enhanced ultrasound (CEUS) in differentiating hepatocellular carcinoma (HCC) vs. intrahepatic cholangiocarcinoma (ICC) and primary liver cancer vs. benign liver lesions for surgical decision making. Methods: Data from 328 patients (296 primary liver cancer patients: 232 HCC and 64 ICC patients and 32 benign hepatic lesion patients) who underwent hepatectomy at our center were retrospectively collected from 2010 to 2015...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29133247/contrast-enhanced-ultrasound-identifies-hepatocellular-carcinoma-in-cirrhosis-a-large-multicenter-retrospective-study
#5
Eleonora Terzi, Massimo Iavarone, Maurizio Pompili, Letizia Veronese, Giuseppe Cabibbo, Mirella Fraquelli, Laura Riccardi, Ludovico De Bonis, Angelo Sangiovanni, Simona Leoni, Maria Assunta Zocco, Sandro Rossi, Nicola Alessi, Stephanie R Wilson, Fabio Piscaglia, Alessandro Granito, Veronica Salvatore, Francesco Tovoli, Matteo Angelo Manini, Gian Lodovico Rapaccini, Maria Elena Ainora, Valentina Ravetta, Giorgia Ghittoni, Agostino Ventra, Giuseppe Mogavero
BACKGROUND & AIMS: The use of contrast enhanced ultrasound (CEUS) for the diagnosis of hepatocellular carcinoma (HCC) in cirrhosis was questioned for the risk of false positive diagnosis in case of cholangiocarcinoma. The American College of Radiology has recently released a scheme (CEUS LI-RADS) classifying lesions at risk for HCC investigated by CEUS. Aim of the present study was to validate this LI-RADS scheme for the diagnosis of HCC. METHODS: A total of 1006 nodules in 848 patients with chronic liver disease at risk for HCC collected in 5 Italian centers were retrospectively analyzed...
November 10, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29131073/an-introduction-to-contrast-enhanced-ultrasound-for-nephrologists
#6
Emily H Chang
Contrast-enhanced ultrasound (CEUS) is an emerging technology with no known nephrotoxicity. CEUS has been utilized in cardiac and abdominal imaging for decades in Asia and Europe and has recently received greater attention in the United States with its approval for characterization of indeterminate liver lesions. Emerging data suggest that CEUS has potential as a diagnostic imaging tool among individuals who have contraindications to CT and MRI. Few nephrologists are aware of CEUS and even fewer are aware of its potential applications among individuals with kidney disease...
November 9, 2017: Nephron
https://www.readbyqxmd.com/read/29126753/usefulness-of-contrast-enhanced-ultrasound-in-differentiating-inflammatory-bowel-disease-from-colon-cancer
#7
Fan Zhang, Li-Ying Miao, Hui-Yu Ge, Shi Tan, Zhi-Qiang Li, Bo Zhao
To evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) in differential diagnosis of inflammatory bowel disease (IBD) and colon cancer, we enrolled 51 patients with thickened bowel walls (13 with IBD and 38 with colon cancer). Ultrasound and CEUS were performed and both qualitative and quantitative features were analyzed. The intestinal wall stratification was preserved in 63.6% of the IBD group but in only 2.6% of the colon cancer group (p <0.01). On CEUS, disordered enhancement and heterogeneous enhancement were shown in only 9...
November 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29126395/contrast-enhanced-ultrasound-of-small-cell-carcinoma-in-urinary-bladder-a-case-report-and-review-of-literature
#8
Meixiang Zhang, Chengcheng Niu, Ming Zhang, Qinghai Peng, Minzhi Ouyang
BACKGROUND: Small cell carcinoma of the urinary bladder (SCCB) is a relatively rare malignant bladder tumor, and few reports have investigated the microvasculature of SCCB imaged using contrast-enhanced ultrasound (CEUS). CASE PRESENTATION: A 63-year-old female was admitted to our hospital after experiencing painless gross hematuria for one week. The gray-scale ultrasound (US) demonstrated a 4.8 × 3.4 × 3.6-cm(3) hypoechoic mass in the apex of the urinary bladder with a wide base and an irregular surface; the mass did not move with changes in body position...
November 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29125333/enhanced-pre-operative-axillary-staging-using-intradermal-microbubbles-and-contrast-enhanced-ultrasound-to-detect-and-biopsy-sentinel-lymph-nodes-in-breast-cancer-a-potential-replacement-for-axillary-surgery
#9
Karina Cox, Sian Taylor-Phillips, Nisha Sharma, Jennifer Weeks, Philippa Mills, Ali Sever, Adrian Lim, Isobel Haigh, Mohamed Hashem, Tania D'Silva, Keshthra Satchithananda, Mengxing Tang, Matthew Wallis
OBJECTIVE: To compare the experience of 4 UK Centres in the use of intradermal microbubbles and contrast enhanced ultrasound (CEUS) to pre-operatively identify and biopsy sentinel lymph nodes (SLN) in patients with breast cancer. METHODS: In all centres, breast cancer patients had a microbubble/ CEUS SLN core biopsy prior to axillary surgery and patients in Centres 1 and 2 had a normal grey-scale axillary ultrasound. Data was collected between 2010 and 2016; 1361 from Centre 1 (prospective, sequential), 376 from Centre 2 (retrospective, sequential), 122 from Centre 3 (retrospective, selected) and 48 from Centre 4 (prospective, selected)...
November 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29122222/imaging-features-of-combined-hepatocellular-cholangiocarcinoma-on-contrast-enhanced-ultrasound-correlation-with%C3%A2-clinicopathological-findings
#10
J Ye, X Xie, Y Lin, B Liu, W Wang, X Huang, G Huang
AIM: To evaluate the relationship between the imaging features of combined hepatocellular-cholangiocarcinoma (CHC) on contrast-enhanced ultrasound (CEUS) and clinicopathological findings. MATERIALS AND METHODS: From August 2004 to August 2016, 40 patients (29 males, 11 females; mean age 52.8±11.2 years) with histopathologically proven CHC were investigated. The CEUS imaging features and clinicopathological findings of CHC were analysed and compared retrospectively...
November 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29122221/qualitative-and-quantitative-contrast-enhanced-ultrasonography-for-the-characterisation-of-non-palpable-testicular-tumours
#11
A Luzurier, F Maxwell, J M Correas, G Benoit, V Izard, S Ferlicot, J P Teglas, M F Bellin, L Rocher
AIM: To assess the diagnostic performance of conventional ultrasound (US) and contrast-enhanced ultrasonography (CEUS) in the differential diagnosis of non-palpable intratesticular tumours. MATERIALS AND METHODS: The local ethics review board approved the protocol, and all of the patients provided written informed consent. Between December 2011 and February 2014, men with non-palpable testicular tumours and normal tumour markers who were referred for surgery were included...
November 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29110052/contrast-enhanced-ultrasonography-for-assessment-of-tubular-atrophy-interstitial-fibrosis-in-immunoglobulin-a-nephropathy-a-preliminary-clinical-study
#12
Wenqi Yang, Shan Mou, Yao Xu, Jing Du, Li Xu, Fenghua Li, Hongli Li
PURPOSE: To investigate the potential of contrast-enhanced ultrasonography (CEUS) for evaluating the severity of tubular atrophy/interstitial fibrosis (TA/IF) in immunoglobulin A nephropathy (IgAN) patients. MATERIALS AND METHODS: A total of 80 patients with IgAN and 33 healthy adults were investigated. Patients were divided into three groups according to the TA/IF (T) grade of the Oxford classification: T0 (n = 28), T1 (n = 35), and T2 (n = 17). Patients and control subjects underwent conventional ultrasound (US) and CEUS...
November 6, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29108077/characterization-of-focal-liver-lesions-using-ceus-and-mri-with-liver-specific-contrast-media-experience-of-a-single-radiologic-center
#13
Lukas Philipp Beyer, Florian Wassermann, Benedikt Pregler, Katharina Michalik, Janine Rennert, Isabel Wiesinger, Christian Stroszczynski, Philipp Wiggermann, Ernst Michael Jung
Aim The purpose of this study was to compare contrast-enhanced ultrasound (CEUS), magnetic resonance imaging (MRI) using liver-specific contrast agent and a combination of both for the characterization of focal liver lesions (FLL). Methods 83 patients with both benign and malignant liver lesions were examined using CEUS and MRI after the intravenous administration of liver-specific contrast media. All patients had inconclusive results from prior imaging examinations. Histopathological specimens could be obtained in 53 patients...
November 6, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29105814/late-onset-type-i-endoleak-characterized-by-contrast-enhanced-ultrasound-after-endovascular-repair-of-aortic-aneurysm
#14
John Nathan Gifford, Hsueh Wen Cheong, Wey Chyi Teoh
We report in the case of a patient with an intra-abdominal aortic aneurysm treated with endovascular aneurysm repair (EVAR) who developed renal impairment during the period of follow up. The repair was complicated with an early-onset type II endoleak which later evolved into a late-onset type I endoleak. It was treated with proximal extension of stent graft, with treatment success and follow-up documented on contrast enhanced ultrasound (CEUS). This case illustrates the usefulness of CEUS in post-EVAR surveillance and emphasizes the need for life-long monitoring as late-onset complications are not uncommon...
November 4, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29104644/contrast-enhanced-ultrasonography-features-of-papillary-thyroid-carcinoma-for-predicting-cervical-lymph-node-metastasis
#15
Ying Liu, Hong Zhou, Peng Yang, Yang Zhou, Jian Wu, Changyu Chen, Ming Ye, Jing Luo
The present study was performed to evaluate the predictive value of contrast-enhanced ultrasonography (CEUS) for the risk of cervical lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC). Between May 2014 and November 2016, 42 patients who received surgery for suspicious PTCs were enrolled in the present study. Each individual underwent CEUS with conventional ultrasound (US), preoperative US-guided fine needle aspiration and personalized surgery. Subsequently, the microvascular density (MVD) of all surgical specimens was measured...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29103478/liver-investigations-updating-on-us-technique-and-contrast-enhanced-ultrasound-ceus
#16
REVIEW
Valentina Battaglia, Rosa Cervelli
Over the past few years, the cross sectional imaging techniques (Computed Tomography - CT and Magnetic Resonance - MR) have improved, allowing a more efficient study of focal and diffuse liver diseases. Many papers had been published about the results of a routinely clinical use of the dual source/dual energy CT techniques and the use of hepatobiliary contrast agents in MR liver studies. As a consequence, these new improvements have diverted the attention away from the Ultrasound technique and its technical and conceptual evolutions...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29100457/nanobubbles-as-ultrasound-contrast-agent-for-facilitating-small-cell-lung-cancer-imaging
#17
Jin-Ping Wang, Xiao-Lin Zhou, Ji-Ping Yan, Rong-Qin Zheng, Wei Wang
Background: This study is to investigate whether liposome-loaded nanobubbles (NBs) have the potentials to carry anti-pro-gastrin releasing peptide (proGRP) antibody and enhance ultrasound imaging of small cell lung cancer (SCLC). Methods: NBs were loaded with an antibody against SCLC (H446 cell line). A nude mouse model of SCLC tumor was established by a subcutaneous injection of tumor cell suspension in the dorsal skin. Images for contrast-enhanced ultrasound (CEUS) of xenograft tumors in the model were obtained through an intravenous injection of blank and targeting NBs...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29097912/automated-generation-of-reliable-blood-velocity-parameter-maps-from-contrast-enhanced-ultrasound-data
#18
Benjamin Theek, Tatjana Opacic, Diana Möckel, Georg Schmitz, Twan Lammers, Fabian Kiessling
Objectives: The purpose of this study was the automated generation and validation of parametric blood flow velocity maps, based on contrast-enhanced ultrasound (CEUS) scans. Materials and Methods: Ethical approval for animal experiments was obtained. CEUS destruction-replenishment sequences were recorded in phantoms and three different tumor xenograft mouse models. Systematic pixel binning and intensity averaging was performed to generate parameter maps of blood flow velocities with different pixel resolution...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29094174/contrast-enhanced-ultrasound-of-malignant-liver-lesions
#19
Isabelle Durot, Stephanie R Wilson, Jürgen K Willmann
Contrast-enhanced ultrasound (CEUS) is a safe, relatively inexpensive, and widely available imaging technique using dedicated imaging ultrasound sequences and FDA-approved contrast microbubbles that allow detection and characterization of malignant focal liver lesions with high diagnostic accuracy. CEUS provides dynamic real-time imaging with high spatial and temporal capability, allowing for unique contributions to the already established protocols for diagnosing focal liver lesions using CT and MR imaging...
November 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29082796/thermal-ablation-of-hepatocellular-carcinoma-in-patients-with-abnormal-coagulation-function
#20
Qiannan Huang, Erjiao Xu, Lei Tan, Qingjing Zeng, Rongqin Zheng, Kai Li
OBJECTIVE: To evaluate the safety of thermal ablation for hepatocellular carcinoma (HCC) in patients with abnormal coagulation function. METHODS: Fifty-seven HCC tumours in 50 patients were treated with thermal ablation. All patients had a meted platelet count <50 × 10(9)/L or international normalised ratio (INR) ≥ 1.7. Gastroscopy before ablation, platelet concentrate or fresh frozen plasma transfusion during ablation and contrast enhanced ultrasoundgraphy (CEUS)-guided ablation to cease needle tract bleeding were performed to reduce haemorrhage...
October 30, 2017: International Journal of Hyperthermia
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