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https://www.readbyqxmd.com/read/28101352/shear-wave-elastography-and-contrast-enhanced-ultrasonography-in-the-diagnosis-of-thyroid-malignant-nodules
#1
Mei Chen, Ke-Qin Zhang, You-Feng Xu, Sheng-Min Zhang, Yong Cao, Wei-Qun Sun
The aim of the present study was to evaluate the value of shear wave elastography (SWE) and contrast-enhanced ultrasonography (CEUS) in the diagnosis of thyroid malignant nodules. A total of 253 patients with 319 thyroid nodules were subjected to two-dimensional ultrasound (2DUS) and CEUS examinations prior to thyroidectomy between March, 2014 and December, 2015. Young's modulus value for each nodule on 2DUS and CEUS images were recorded. The sensitivity, specificity and accuracy of 2DUS, SWE and CEUS in the diagnosis of thyroid malignant nodules were assessed...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28096725/added-value-of-contrast-enhanced-ultrasound-on-biopsies-of-focal-hepatic-lesions-invisible-on-fusion-imaging-guidance
#2
Tae Wook Kang, Min Woo Lee, Kyoung Doo Song, Mimi Kim, Seung Soo Kim, Seong Hyun Kim, Sang Yun Ha
OBJECTIVE: To assess whether contrast-enhanced ultrasonography (CEUS) with Sonazoid can improve the lesion conspicuity and feasibility of percutaneous biopsies for focal hepatic lesions invisible on fusion imaging of real-time ultrasonography (US) with computed tomography/magnetic resonance images, and evaluate its impact on clinical decision making. MATERIALS AND METHODS: The Institutional Review Board approved this retrospective study. Between June 2013 and January 2015, 711 US-guided percutaneous biopsies were performed for focal hepatic lesions...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28070162/contrast-enhanced-ultrasonography-in-evaluation-of-the-therapeutic-effect-of-chemotherapy-for-patients-with-liver-metastases
#3
Naoyuki Ueda, Haruki Nagira, Naoko Sannomiya, Saeko Ikunishi, Yuiko Hattori, Akira Kamida, Yuki Koyanagi, Kenta Shimabayashi, Kengo Sato, Hiroaki Saito, Yasuaki Hirooka
BACKGROUND: The therapeutic effect of chemotherapy for liver metastases is currently determined by changes in tumor diameter depicted on computed tomography (CT) and magnetic resonance imaging, but it cannot accurately determine if there is central necrosis. Furthermore, due to the risk of radiation exposure and high cost, frequent examination using these methods places a heavy burden on patients. Meanwhile, real-time observation of blood flow and vessel morphology within tumors has become possible by contrast-enhanced ultrasonography (CEUS)...
December 2016: Yonago Acta Medica
https://www.readbyqxmd.com/read/28060884/contrast-enhanced-ultrasound-with-vegfr2-targeted-microbubbles-for-monitoring-regorafenib-therapy-effects-in-experimental-colorectal-adenocarcinomas-in-rats-with-dce-mri-and-immunohistochemical-validation
#4
Ralf Stefan Eschbach, Dirk-Andre Clevert, Heidrun Hirner-Eppeneder, Michael Ingrisch, Matthias Moser, Jessica Schuster, Dina Tadros, Moritz Schneider, Philipp Maximilian Kazmierczak, Maximilian Reiser, Clemens C Cyran
OBJECTIVES: To investigate contrast-enhanced ultrasound (CEUS) with VEGFR2-targeted microbubbles for monitoring therapy effects of regorafenib on experimental colon carcinomas in rats with correlation to dynamic contrast-enhanced MRI (DCE-MRI) and immunohistochemistry. MATERIALS AND METHODS: Human colorectal adenocarcinoma xenografts (HT-29) were implanted subcutaneously in n = 21 (n = 11 therapy group; n = 10 control group) female athymic nude rats (Hsd: RH-Foxn1rnu)...
2017: PloS One
https://www.readbyqxmd.com/read/28034569/evaluation-of-hepatocellular-carcinoma-tumor-vascularity-using-contrast-enhanced-ultrasonography-as-a-predictor-for-local-recurrence-following-radiofrequency-ablation
#5
Tomohiro Ishii, Kazushi Numata, Yoshiteru Hao, Nobutaka Doba, Koji Hara, Masaaki Kondo, Katsuaki Tanaka, Shin Maeda
PURPOSE: The purpose of this study was to evaluate whether the hypervascularity of hepatocellular carcinomas (HCCs) on contrast-enhanced ultrasonography (CEUS) prior to radiofrequency ablation (RFA) is a significant risk factor for local recurrence after RFA. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained. Overall, 208 patients (mean age, 71.7 years; range, 50-87 years; 137 men, 71 women) with 282 HCCs treated with RFA were analyzed retrospectively...
December 21, 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/28032907/multiparametric-sonography-of-hematologic-malignancies-of-the-testis-grayscale-color-doppler-and-contrast-enhanced-ultrasound-and-strain-elastographic-appearances-with-histologic-correlation
#6
Carolina Kachramanoglou, Vasileios Rafailidis, Marianna Philippidou, Michele Bertolotto, Dean Y Huang, Annamaria Deganello, Maria E Sellars, Paul S Sidhu
Primary testicular lymphoma is rare and appears with nonspecific findings on grayscale and color Doppler sonography. We present 8 patients further examined with contrast-enhanced sonography, strain elastography, and histologic analysis after orchiectomy. Seven of 8 patients had a diagnosis of large B-cell lymphoma, and 1 of 8 had a diagnosis of granulocytic sarcoma, with solitary lesions (2 of 8), multiple lesions (3 of 8), or entire testicular involvement (3 of 8). Lesions appeared hypoechoic (7 of 8) or isoechoic (1 of 8), all with increased vascularity on color Doppler sonography and a nonbranching linear pattern of intratumoral vessels (7 of 8)...
December 29, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28029495/an-algorithm-of-image-heterogeneity-with-contrast-enhanced-ultrasound-in-differential-diagnosis-of-solid-thyroid-nodules
#7
Lifang Jin, Changsong Xu, Xueqian Xie, Fan Li, Xiuhong Lv, Lianfang Du
Enhancement heterogeneity on contrast-enhanced ultrasonography (CEUS) is used to differentiate between benign and malignant thyroid nodules. In this study, we used an algorithm to quantify enhancement heterogeneity of solid thyroid nodules on CEUS. The heterogeneity value (HV) is calculated as standard deviation/mean intensity × 100 (using Adobe Photoshop). The heterogeneity ratio (HR) is calculated as the ratio of the HV of the nodule to that of the surrounding parenchyma. Three phases-ascending, peak and descending phases-were studied...
October 28, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28024660/a-novel-approach-to-detecting-postpartum-hemorrhage-using-contrast-enhanced-ultrasound
#8
Kenji Imai, Tomomi Kotani, Hiroyuki Tsuda, Tomoko Nakano, Akihiro Hirakawa, Fumitaka Kikkawa
The aim of this study was to estimate the efficacy of contrast-enhanced ultrasound (CEUS) in detecting postpartum hemorrhage (PPH) after cesarean section. This is the first study of CEUS in obstetric hemorrhage. A total of 37 patients, operated at Nagoya University Hospital, underwent CEUS. We evaluated the findings of CEUS, which were qualitatively defined as positive when pooling or leakage of contrast agent was observed in the uterine cavity, by measuring the amount of bleeding during the first 4 h after cesarean section...
December 23, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28017583/three-dimensional-contrast-enhanced-ultrasound-improves-endoleak-detection-and-classification-after-endovascular-aneurysm-repair
#9
Christopher Lowe, Abeera Abbas, Steven Rogers, Lee Smith, Jonathan Ghosh, Charles McCollum
BACKGROUND: Three-dimensional contrast-enhanced ultrasound (3D-CEUS) is a novel technology allowing surgeons to view duplex ultrasound images in three dimensions with ultrasound contrast highlighting blood flow in endoleaks after endovascular aneurysm repair (EVAR). It potentially reduces the need for computed tomography angiography (CTA) and catheter angiography. This study compares 3D-CEUS with both CTA and the final vascular multidisciplinary team (MDT) diagnosis using all available imaging...
December 22, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28009476/testing-the-efficacy-of-contrast-enhanced-ultrasound-in-detecting-transplant-rejection-using-a-murine-model-of-heart-transplantation
#10
Krisztina Fischer, Shunsuke Ohori, F Can Meral, Mayuko Uehara, Silvia Giannini, Takaharu Ichimura, R Neal Smith, Ferenc A Jolesz, Indira Guleria, Yongzhi Zhang, Philip Jason White, Nathan J McDannold, Karin Hoffmeister, Michael M Givertz, Reza Abdi
One of the key unmet needs to improve long-term outcomes of heart transplantation is to develop accurate, non-invasive and practical diagnostic tools to detect transplant rejection. Early intra-graft inflammation and endothelial cell injuries occur prior to advanced transplant rejection. We developed a novel diagnostic imaging platform to detect early declines in micro-vascular perfusion (MP) of cardiac transplants using Contrast Enhanced Ultrasonography (CEUS). The efficacy of CEUS in detecting transplant rejection was tested in a murine model of heart transplants, a standard preclinical model of solid organ transplant...
December 23, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/28008454/intra-arterial-contrast-enhanced-ultrasound-ia-ceus-for-localization-of-hepatocellular-carcinoma-hcc-supply-during-transarterial-chemoembolization-tace-a-case-series
#11
Ilya Lekht, Megha Nayyar, Brian Luu, Phillip L Guichet, Jessica Ho, Ramon Ter-Oganesyan, Michael Katz, Mittul Gulati
Transarterial chemoembolization (TACE) is a proven catheter-based locoregional therapy for treatment of hepatocellular carcinoma (HCC). Drug-eluting bead TACE involves delivering micrometer-sized particles preloaded with doxorubicin directly to the tumor via its arterial blood supply and results in vascular embolization with intra-tumoral drug release. Effective therapy requires mapping of the tumor arterial supply, which in some cases cannot be accomplished with conventional angiographic techniques alone. Contrast-enhanced ultrasound (CEUS) is an imaging technique which utilizes microbubble contrast agents to demonstrate blood flow and tissue perfusion, enabling tumor visualization in real time...
December 23, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27999819/detection-of-the-single-session-complete-ablation-rate-by-contrast-enhanced-ultrasound-during-ultrasound-guided-laser-ablation-for-benign-thyroid-nodules-a-prospective-study
#12
Shuhua Ma, Ping Zhou, Xiaomin Wu, Shuangming Tian, Yongfeng Zhao
This study aimed to investigate the single-session complete ablation rate of ultrasound-guided percutaneous laser ablation (LA) for benign thyroid nodules. LA was performed in 90 patients with 118 benign thyroid nodules. Contrast-enhanced ultrasound (CEUS) was used to evaluate complete nodule ablation one day after ablation. Thyroid nodule volumes, thyroid functions, clinical symptoms and complications were evaluated 1, 3, 6, 12, and 18 months after ablation. Results showed that all benign thyroid nodules successfully underwent LA...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27995384/quantitative-imaging-by-pixel-based-contrast-enhanced-ultrasound-reveals-a-linear-relationship-between-synovial-vascular-perfusion-and-the-recruitment-of-pathogenic-il-17a-f-il-23-cd161-cd4-t-helper-cells-in-psoriatic-arthritis-joints
#13
Ugo Fiocco, Roberto Stramare, Veronica Martini, Alessandro Coran, Francesco Caso, Luisa Costa, Mara Felicetti, Gaia Rizzo, Matteo Tonietto, Anna Scanu, Francesca Oliviero, Bernd Raffeiner, Maristella Vezzù, Francesca Lunardi, Raffaele Scarpa, David Sacerdoti, Leopoldo Rubaltelli, Leonardo Punzi, Andrea Doria, Enrico Grisan
To develop quantitative imaging biomarkers of synovial tissue perfusion by pixel-based contrast-enhanced ultrasound (CEUS), we studied the relationship between CEUS synovial vascular perfusion and the frequencies of pathogenic T helper (Th)-17 cells in psoriatic arthritis (PsA) joints. Eight consecutive patients with PsA were enrolled in this study. Gray scale CEUS evaluation was performed on the same joint immediately after joint aspiration, by automatic assessment perfusion data, using a new quantification approach of pixel-based analysis and the gamma-variate model...
December 20, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27986175/contrast-enhanced-ultrasound-in-focal-liver-lesions-where-do-we-stand
#14
Tommaso Vincenzo Bartolotta, Federica Vernuccio, Adele Taibbi, Roberto Lagalla
Contrast-enhanced ultrasound (CEUS) represents a significant breakthrough in sonography, and it is being increasingly used for the evaluation of focal liver lesions (FLLs). Currently, CEUS is included as a part of the suggested diagnostic workup of FLLs, resulting in a better patient management and delivering cost-effective therapy. After a brief technical note, contrast-enhancement patterns of different types of benign and malignant FLLs, along with hepatic pseudolesions, are described and discussed based on our experience and literature data...
December 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27983547/factors-associated-with-initial-incomplete-ablation-for-benign-thyroid-nodules-after-radiofrequency-ablation-first-results-of-ceus-evaluation
#15
Chong-Ke Zhao, Hui-Xiong Xu, Feng Lu, Li-Ping Sun, Ya-Ping He, Le-Hang Guo, Xiao-Long Li, Xiao-Wan Bo, Wen-Wen Yue
OBJECTIVE: To assess the factors associated with initial incomplete ablation (ICA) after radiofrequency ablation for benign thyroid nodules (BTNs). MATERIALS AND METHODS: 69 BTNs (mean volume 6.35±5.66 ml, range 1.00-25.04 ml) confirmed by fine-needle aspiration cytology (FNAC) in fifty-four patients were treated with ultrasound-guided percutaneous radiofrequency ablation (RFA) and the local treatment efficacy was immediately assessed by intra-procedural contrast-enhanced ultrasound (CEUS)...
December 14, 2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27981306/contrast-enhanced-ultrasound-and-computed-tomography-assessment-of-hepatocellular-carcinoma-after-transcatheter-arterial-chemo-embolization-a-systematic-review
#16
REVIEW
Cheng-Jeng Tai, Ming-Te Huang, Chih-Hsiung Wu, Chen-Jei Tai, Yeu-Ching Shi, Chun-Chao Chang, Yu-Jia Chang, Li-Jen Kuo, Po-Lei Wei, Ray-Jade Chen, Hung-Yi Chiou
BACKGROUND AND AIMS: Contrast-enhanced ultrasound (CEUS) and contrast-enhanced computed tomography (CECT) are used to assess the response of hepatocellular carcinoma after transarterial chemoembolization. Our aim was to perform a systematic review to compare CEUS and CECT for therapeutic response assessment to transarterial chemoembolization in the treatment of hepatocellular carcinoma. METHOD: PubMed, Embase, and the Cochrane Library databases were searched from inception until January 1, 2016...
December 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27981275/the-impact-of-microbubble-enhanced-therapeutic-ultrasound-combined-with-prothrombin-on-microwave-ablation-in-the-rabbit-liver
#17
Ying Shi, Xinyue Liu, Zhenli Luo, Fen Gu, Jianguo He, Ping Yan, Junwang Zhang, Xiaodong Zhou
AIM: This study aimed to investigate the effect of microbubble-enhanced ultrasound (MEUS) combined with prothrombin on regional hepatic circulation and microwave ablation (MWA) in rabbit livers. MATERIALS AND METHODS: High-pressureamplitude therapeutic ultrasound (TUS) was used to treat 52 surgically exposed livers of healthy New Zealand rabbits: 13 livers were treated with MEUS alone, 13 with MEUS and prothrombin (PMEUS), 13 with ultrasound plus normal saline and 13 with ultrasound plus prothrombin as controls...
December 5, 2016: Medical Ultrasonography
https://www.readbyqxmd.com/read/27973352/contrast-enhanced-ultrasound-by-real-time-spatiotemporal-filtering-of-ultrafast-images
#18
Yann Desailly, Anne-Marie Tissier, Jean-Michel Correas, Frédéric Wintzenrieth, Mickaël Tanter, Olivier Couture
Contrast enhanced ultrasound (CEUS) takes advantage of the nonlinear behaviour of injected microbubbles. If these contrast techniques yield good specificity between bubbles and tissues, they suffer some drawbacks, inherently linked to their dependence on nonlinear content. In recent years, plane-wave ultrasound reached frame rates of up to 20 000 fps. In this study we propose a linear technique for CEUS that takes advantage of these very high frame rates to separate bubbles from tissue without requiring nonlinearities...
January 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27965719/what-is-the-role-of-contrast-enhanced-ultrasound-in-the-evaluation-of-the-endoleak-of-aortic-endoprostheses-a-comparison-between-ceus-and-ct-on-a-widespread-scale
#19
E David, V Cantisani, H Grazhdani, L Di Marzo, L Venturini, F Fanelli, M Di Segni, N Di Leo, L Brunese, F Calliada, M Ciccariello, A Bottari, G Ascenti, F D'Ambrosio
OBJECTIVE: To evaluate the accuracy of contrast-enhanced ultrasound (CEUS) in comparison to CT angiography (CTA) to identify and classify endoleaks following abdominal aortic aneurism repair with endoprosthesis. MATERIALS AND METHODS: A retrospective analysis of 181 patients treated with EVAR, from September 2009 to September 2014, was performed. Patients were evaluated with CEUS, CTA and angiography in the cases requiring treatment. Sac diameter, sac integrity, identification and classification of endoleaks were taken into consideration...
December 2016: Journal of Ultrasound
https://www.readbyqxmd.com/read/27959806/bayesian-quantification-of-contrast-enhanced-ultrasound-images-with-adaptive-inclusion-of-an-irreversible-component
#20
Gaia Rizzo, Matteo Tonietto, Marco Castellaro, Bernd Raffeiner, Alessandro Coran, Ugo Fiocco, Roberto Stramare, Enrico Grisan
Contrast Enhanced Ultrasound (CEUS) is a sensitive imaging technique to assess tissue vascularity and it can be particularly useful in early detection and grading of arthritis. In a recent study we have shown that a Gamma-variate can accurately quantify synovial perfusion and it is flexible enough to describe many heterogeneous patterns. However, in some cases the heterogeneity of the kinetics can be such that even the Gamma model does not properly describe the curve, with a high number of outliers.
December 8, 2016: IEEE Transactions on Medical Imaging
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