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https://www.readbyqxmd.com/read/29345146/quantitative-contrast-enhanced-ultrasound-for-monitoring-vedolizumab-therapy-in-inflammatory-bowel-disease-patients-a-pilot-study
#1
Ruediger S Goertz, Daniel Klett, Dane Wildner, Raja Atreya, Markus F Neurath, Deike Strobel
Background Microvascularization of the bowel wall can be visualized and quantified non-invasively by software-assisted analysis of derived time-intensity curves. Purpose To perform software-based quantification of bowel wall perfusion using quantitative contrast-enhanced ultrasound (CEUS) according to clinical response in patients with inflammatory bowel disease treated with vedolizumab. Material and Methods In a prospective study, in 18 out of 34 patients, high-frequency ultrasound of bowel wall thickness using color Doppler flow combined with CEUS was performed at baseline and after 14 weeks of treatment with vedolizumab...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29333116/is-there-a-role-for-contrast-enhanced-ultrasound-in-the-detection-and-biopsy-of-mri-only-visible-breast-lesions
#2
Aki Nykänen, Otso Arponen, Anna Sutela, Ritva Vanninen, Mazen Sudah
Background: This study aimed to evaluate the feasibility of contrast-enhanced ultrasound (CEUS) and CEUS-guided interventions in the diagnostics of MRI visible targeted US occult breast lesions. Patients and methods: This retrospective study examined 10 females with 10 occult, MRI only detected breast lesions between July 2014 and April 2017. Targeted second look US followed by CEUS with 2.4 ml of SonoVue® were performed for all of the lesions. After positive CEUS localization the same dose was repeated for confirmation and CEUS-guided interventions were performed...
December 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/29332247/practical-advantages-of-contrast-enhanced-ultrasound-in-abdominopelvic-radiology
#3
Praveen Ganti Ranganath, Michelle L Robbin, Susan J Back, Edward G Grant, David T Fetzer
Computed tomography (CT) and magnetic resonance imaging (MRI) are two of the workhorse modalities of abdominopelvic radiology. However, these modalities are not without patient- and technique-specific limitations that may prevent a timely and accurate diagnosis. Contrast-enhanced ultrasound (CEUS) is an effective, rapid, and cost-effective imaging modality with expanding clinical utility in the United States. In this pictorial essay, we provide a case-based discussion demonstrating the practical advantages of CEUS in evaluating a variety of pathologies in which CT or MRI was precluded or insufficient...
January 13, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29331357/differentiation-of-inflammatory-from-fibrotic-ileal-strictures-among-patients-with-crohn-s-disease-based-on-visual-analysis-feasibility-study-combining-conventional-b-mode-ultrasound-contrast-enhanced-ultrasound-and-strain-elastography
#4
Emilio Quaia, Antonio Giulio Gennari, Maria Assunta Cova, Edwin J R van Beek
The aim of this pilot study was to assess prospectively the feasibility of conventional B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) combined with real-time strain elastography (SE) in the differentiation of inflammatory from fibrotic ileal strictures among patients with Crohn's disease (CD) based on visual analysis. Twenty non-consecutive patients (15 male and 5 female; mean age ± standard deviation, 40.2 ± 10.22 y) with CD and stricture of the terminal ileal loop were scanned by conventional B-mode US and CEUS and, subsequently, by real-time SE...
January 10, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29322796/pitfalls-of-contrast-enhanced-ultrasound-ceus-in-determination-of-breast-tumor-biological-dignity
#5
V Lehotska, K Rauova, L Vanovcanova
The aim of this prospective study was to identify characteristics of breast lesions on contrast enhanced ultrasound (CEUS) that can be a source of diagnostic ambiguity and cause under- or overestimation of examined breast lesions. 215 women (range 23-76 y., mean age 53.16 y) with 215 breast lesions were examined by B-mode ultrasound, followed by CEUS and core biopsy. CEUS parameters: degree of opacification, character of washout and preliminary CEUS result (suspicious, non-suspicious, uncertain) were subsequently correlated with histopathological outcomes...
2018: Neoplasma
https://www.readbyqxmd.com/read/29312973/critical-appraisal-of-chinese-2017-guideline-on-the-management-of-hepatocellular-carcinoma
#6
REVIEW
Di-Yang Xie, Zheng-Gang Ren, Jian Zhou, Jia Fan, Qiang Gao
Hepatocellular carcinoma (HCC) is the fourth most common and the third most lethal cancer in China. An updated version of consensus-based recommendations on the management of HCC has been recently published by a multidisciplinary group of Chinese experts including liver surgeons, hepatic oncologists, radiologists and pathologists. Major changes have been made to the diagnostic criteria. In addition to dynamic multi-detector computed tomography (CT) and magnetic resonance imaging (MRI), gadoxetic acid-enhanced MRI and contrast-enhanced ultrasound (CEUS) are added to the diagnostic imaging tests...
December 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29307931/common-and-uncommon-features-of-focal-splenic-lesions-on-contrast-enhanced-ultrasound-a-pictorial-review
#7
Julia D Zavariz, Eleni Konstantatou, Annamaria Deganello, Diana Bosanac, Dean Y Huang, Maria E Sellars, Paul S Sidhu
The characterization of focal splenic lesions by ultrasound can be quite challenging. The recent introduction of contrast-enhanced ultrasound (CEUS) has come to play a valuable role in the field of imaging splenic pathologies, offering the possibility of an ionizing radiation-free investigation. Because CEUS has been incorporated into everyday clinical practice, malignant diseases such as focal lymphomatous infiltration, metastatic deposits, benign cysts, traumatic fractures, and hemangiomas can now be accurately depicted and characterized without the need for further imaging...
November 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/29299367/contrast-enhanced-ultrasound-guided-biopsies-of-liver-lesions-not-visualized-on-standard-b-mode-ultrasound-preliminary-experience
#8
Sasan Partovi, Ziang Lu, Rivka Kessner, Alice Yu, Yasmine Ahmed, Indravadan J Patel, Dean A Nakamoto, Nami Azar
Background: To assess the technical success of contrast enhanced ultrasound (CEUS) guided biopsies of liver lesions poorly visualized on B-mode ultrasound. Methods: Patients were selected during the procedure based on the real-time clinical scenario of unsatisfactory B-mode ultrasound lesion visualization and all patients would have otherwise undergone CT guided liver lesion biopsy. A total of 26 patients underwent CEUS guided biopsy and were included in this retrospective analysis...
December 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29290798/ultrasound-molecular-imaging-of-vegfr-2-in-clear-cell-renal-cell-carcinoma-tracks-disease-response-to-antiangiogenic-and-notch-inhibition-therapy
#9
Juan D Rojas, Fanglue Lin, Yun-Chen Chiang, Anna Chytil, Diana C Chong, Victoria L Bautch, W Kimryn Rathmell, Paul A Dayton
Metastatic clear-cell renal cell carcinoma (ccRCC) affects thousands of patients worldwide each year. Antiangiogenic therapy has been shown to have beneficial effects initially, but resistance is eventually developed. Therefore, it is important to accurately track the response of cancer to different therapeutics in order to appropriately adjust the therapy to maximize efficacy. Change in tumor volume is the current gold standard for determining efficacy of treatment. However, functional variations can occur much earlier than measurable volume changes...
2018: Theranostics
https://www.readbyqxmd.com/read/29282853/contrast-enhanced-ultrasound-using-bolus-injections-of-contrast-agent-for-assessment-of-postprandial-microvascular-blood-volume-in-human-skeletal-muscle
#10
Kenneth H Mertz, Jacob Bülow, Lars Holm
Methods capable of measuring blood flow in a tissue-specific manner are needed. The purpose of this study was to investigate whether contrast-enhanced ultrasound (CEUS) using bolus injections of SonoVue® is an useful method for assessing postprandial changes in microvascular perfusion in the vastus lateralis muscle. Ten healthy, young subjects were recruited for this study. Six subjects participated in washout and reproducibility protocols to assess washout time of SonoVue® and the reproducibility of the method when measuring microvascular blood volume (MBV)...
December 27, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29281991/superb-microvascular-imaging-smi-compared-with-conventional-ultrasound-for-evaluating-thyroid-nodules
#11
Ruigang Lu, Yuxin Meng, Yan Zhang, Wei Zhao, Xun Wang, Mulan Jin, Ruijun Guo
BACKGROUND: Superb microvascular imaging (SMI) for depiction of microvascular flow in thyroid nodules was compared with color/power Doppler imaging (CDI/PDI) and contrast-enhanced ultrasonography (CEUS). In addition, the diagnostic performance of conventional ultrasound combined with SMI for differentiating benign and malignant thyroid nodules was evaluated. METHODS: Preoperative conventional ultrasound consisting of gray-scale ultrasonography and CDI/PDI, followed by SMI and CEUS, was used to record 52 thyroid nodules...
December 28, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/29279500/hepatic-angiomyolipoma-staining-in-the-post-vascular-phase-of-contrast-enhanced-ultrasound-due-to-the-presence-of-macrophages
#12
Kei Endo, Hidekatsu Kuroda, Keisuke Kakisaka, Takayoshi Oikawa, Kei Sawara, Kazuyuki Ishida, Tamotsu Sugai, Yasuhiro Takikawa
A 47-year-old Japanese man was referred to hospital after the detection of a liver tumor. Dynamic computed tomography and Gd-EOB-DTPA-enhanced magnetic resonance imaging were consistent with a diagnosis of hepatocellular carcinoma (HCC). No perfusion defect was observed in the post-vascular phase of contrast-enhanced ultrasound (CEUS). Histopathological staining of the tumor cells was positive for antibodies against HMB-45 and CD68, confirming the diagnosis of hepatic angiomyolipoma (HAML). These findings indicated the presence of macrophages in HAML...
December 27, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29260278/role-of-contrast-enhanced-ultrasound-in-evaluation-of-the-bowel
#13
Alexandra Medellin, Christina Merrill, Stephanie R Wilson
Contrast-enhanced ultrasound (CEUS) of the gastrointestinal tract provides vascular information helpful for characterizing masses and other pathologies in and around the bowel, similar to contrast applications in other solid organs. However, the use of microbubble contrast agents for the bowel provides additional unique contributions as it gives both subjective and objective information about mural and mesenteric blood flow, invaluable for the determination of disease activity in those many patients affected by inflammatory bowel disease (IBD)...
December 19, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29245287/an-inflammatory-myofibroblastic-tumor-in-the-transplanted-liver-displaying-quick-wash-in-and-wash-out-on-contrast-enhanced-ultrasound-a-case-report
#14
Jing Shang, Yun-Yue Wang, Ying Dang, Xin-Juan Zhang, Yan Song, Li-Tao Ruan
RATIONALE: Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal neoplasm, and its presence in a grafted liver is exceedingly rare. PATIENT CONCERNS: A 54-year-old woman was admitted to our hospital with a half-month history of intermittent melena. She had undergone deceased-donor liver transplantation (LT) for hepatitis B virus related liver cirrhosis without hepatocellular carcinoma 5 months previously. DIAGNOSIS: Laboratory examination showed impaired liver and renal functions and Epstein-Barr virus (EBV) infection, but tumor markers within normal ranges...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29243129/contrast-enhanced-ultrasound-for-needle-biopsy-of-central-lung-cancer-with-atelectasis
#15
Zhikai Lei, Jun Lou, Lingyun Bao, Zhuying Lv
PURPOSE: Contrast-enhanced ultrasound (CEUS) can distinguish between central lung cancer and atelectatic lung tissue. The aim of this study was to explore the clinical value of CEUS for biopsy in patients with central lung cancer with obstructive atelectasis. METHODS: One hundred and twelve patients were selected and CEUS was performed to display central lung cancer and atelectatic lung tissue. The front edge of central lung cancer was punctured with a needle, avoiding the necrotic area, under the guidance of CEUS...
December 14, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29238867/a-direct-comparison-of-contrast-enhanced-ultrasound-and-dynamic-contrast-enhanced-magnetic-resonance-imaging-for-prostate-cancer-detection-and-prediction-of-aggressiveness
#16
Alexander D J Baur, Julia Schwabe, Julian Rogasch, Andreas Maxeiner, Tobias Penzkofer, Carsten Stephan, Marc Rudl, Bernd Hamm, Ernst-Michael Jung, Thom Fischer
INTRODUCTION: Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and contrast-enhanced ultrasound (CEUS) analyse tissue vascularization. We evaluated if CEUS can provide comparable information as DCE-MRI for the detection of prostate cancer (PCa) and prediction of its aggressiveness. MATERIAL AND METHODS: A post-hoc evaluation of 92 patients was performed. In each patient CEUS and DCE-MRI parameters of the most suspicious lesion identified on MRI were analysed...
December 13, 2017: European Radiology
https://www.readbyqxmd.com/read/29232725/value-of-contrast-enhanced-ultrasound-quantification-criteria-for-identifying-patients-not-responding-to-bevacizumab-based-therapy-for-colorectal-liver-metastases
#17
François Tranquart, Paul-Armand Dujardin, Olivier Bouché, Claude Marcus, Christophe Borg, Philippe Manzoni, Jean-Yves Douillard, Catherine Labbe-Devilliers, Eric Terrebonne, Denis Smith, Herve Trillaud, Olivier Capitain, Cristophe Aubé, Jean-Philippe Spano, Olivier Lucidarme, Aurélie Ferru, Jean-Pierre Tasu, Sylvain Manfredi, Aurore Bleuzen, Julie Léger, Thierry Lecomte
Purpose To evaluate changes in tumor vascularization parameters based on contrast-enhanced ultrasound (CEUS) quantification criteria of at least one visible liver metastasis as an early predictor of non-response to chemotherapy, including bevacizumab for colorectal cancer (CRC) liver metastases. Materials and Methods This multicenter prospective study included patients who received first-line bevacizumab-based chemotherapy. Tumor enhancement measured using CEUS within one liver metastasis and in relation to the surrounding healthy liver was quantified within 8 days before the first infusion of bevacizumab (E0), 24 hours after the end of the first infusion of bevacizumab (E1), in the 24 hours before the 2nd and 3 rd infusion of bevacizumab on day 15 (E2) and day 30 (E3), respectively, and after 2 months of treatment (E4)...
December 12, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29232723/biopsy-of-liver-target-lesions-under-contrast-enhanced-ultrasound-guidance-a-multi-center-study
#18
Giampiero Francica, Maria Franca Meloni, Ilario de Sio, Fulvia Terracciano, Eugenio Caturelli, Laura Riccardi, Paola Roselli, Maddalena Diana Iadevaia, Mariano Scaglione, Giovanni Lenna, Jason Chiang, Maurizio Pompili
Purpose To retrospectively characterize the prevalence and impact of contrast-enhanced ultrasound (CEUS) as a guidance technique for the biopsy of liver target lesions (LTLs) at six interventional ultrasound centers. Materials and Methods The six participating centers retrospectively selected all patients in whom biopsy needles were positioned in LTLs during CEUS. The prevalence of CEUS-guided biopsies at each center between 2005 and 2016, contrast agent consumption, procedure indications, diagnostic yield and complications were assessed...
December 12, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29230842/use-of-ultrasound-contrast-agents-in-relation-to-percutaneous-interventional-procedures-a-systematic-review-and-pictorial-essay
#19
REVIEW
Christian Pállson Nolsøe, Alexander Bjørneboe Nolsøe, Jeanett Klubien, Hans-Christian Pommergaard, Jacob Rosenberg, Maria Franca Meloni, Torben Lorentzen
The aim of this article is to provide an inventory of the use of contrast-enhanced ultrasound (CEUS) in relation to percutaneous interventional procedures. The article is structured into a systematic literature review followed by a clinical part relating to percutaneous CEUS-guided procedures. A literature search identified 3109 records. After abstract screening, 55 articles were analyzed and supplemented with pictorial material to explain the techniques. In conclusion, the best-evidenced indications for CEUS-guided interventions are biopsy and ablation of inconspicuous or B-mode-invisible tumors, intraprocedural ablation control and follow-up, as well as percutaneous transhepatic cholangiography and drainage procedures...
December 12, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29229267/intracavitary-contrast-enhanced-ultrasound-in-the-management-of-post-surgical-gastrointestinal-fistulas
#20
Er-Jiao Xu, Man Zhang, Kai Li, Zhong-Zhen Su, Ying-Lin Long, Qing-Jin Zeng, Huan-Yi Guo, Rong-Qin Zheng
The goal of this study was to investigate intracavitary contrast-enhanced ultrasound (IC-CEUS) measures in the management of post-surgical gastrointestinal (GI) fistula throughout detection, treatment and follow-up. From June 2010 to August 2016, patients who were administered ultrasound contrast agent (UCA) via a drainage tube for IC-CEUS were enrolled and retrospectively analyzed. They were suspected of having GI anastomotic fistulas or had been found to have fluid collections with ultrasound that were accompanied by abdominal pain or fever after surgical procedures...
December 8, 2017: Ultrasound in Medicine & Biology
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