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Severe malnutrition children

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https://www.readbyqxmd.com/read/28231385/most-children-who-took-part-in-a-comprehensive-malnutrition-programme-in-madagascar-reached-and-maintained-the-recovery-threshold
#1
Magnin Margot, Beat Stoll, Rajaobelina Voahangy, Emilien Jeannot
AIM: The benefits of including nutritional education in programmes that tackle moderate and severe acute malnutrition remain poorly documented. This study in Madagascar evaluated the nutritional status of children who took part in an innovative programme that included maternal education, on completion and after a year. METHODS: Each year, this outpatient programme admits 2,400 malnourished children from 6-59 months in the lower districts of Antananarivo, Madagascar...
February 23, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28229100/diagnosis-of-tuberculosis-following-world-health-organization-recommended-criteria-in-severely-malnourished-children-presenting-with-pneumonia
#2
Mohammod Jobayer Chisti, Mohammed Abdus Salam, Abu S M S B Shahid, K M Shahunja, Sumon Kumar Das, Abu Syed Golam Faruque, Pradip Kumar Bardhan, Tahmeed Ahmed
Evidences on diagnosis of tuberculosis (TB) following the World Health Organization (WHO) criteria in children with severe acute malnutrition (SAM) are lacking. We sought to evaluate the WHO criteria for the diagnosis of TB in such children. In this prospective study, we enrolled SAM children aged <5 with radiological pneumonia. We collected induced sputum and gastric lavage for smear microscopy, mycobacterial culture, and Xpert MTB/RIF. Using the last 2 methods as the gold standard, we determined sensitivity, specificity, and positive and negative predictive values of WHO criteria (n = 388)...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28185414/severe-acute-malnutrition-in-children-aged-under-5%C3%A2-years-can-be-successfully-managed-in-a-non-emergency-routine-community-healthcare-setting-in-ghana
#3
Robert Akparibo, Janet Harris, Lindsay Blank, Mike J Campbell, Michelle Holdsworth
This study investigated the performance of community-based management of severe acute malnutrition (CMAM) within routine healthcare services in Ghana. This was a retrospective cohort study of n = 488 children (6-59 months) who had received CMAM. Data for recovery, default, and mortality rates were obtained from enrolment cards in 56 outpatient centres in Upper East region, Ghana. Satisfactory rates of recovery of 71.8% were reported. Children who were enrolled with higher mid-upper arm circumference (MUAC) ≥11...
February 10, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28176953/survival-status-and-predictors-of-mortality-among-severely-acute-malnourished-children-5-years-of-age-admitted-to-stabilization-centers-in-gedeo-zone-a-retrospective-cohort-study
#4
Tadele Girum, Mesfin Kote, Befikadu Tariku, Henok Bekele
Despite the existence of standard protocol, many stabilization centers (SCs) continue to experience high mortality of children receiving treatment for severe acute malnutrition. Assessing treatment outcomes and identifying predictors may help to overcome this problem. Therefore, a 30-month retrospective cohort study was conducted among 545 randomly selected medical records of children <5 years of age admitted to SCs in Gedeo Zone. Data was entered by Epi Info version 7 and analyzed by STATA version 11. Cox proportional hazards model was built by forward stepwise procedure and compared by the likelihood ratio test and Harrell's concordance, and fitness was checked by Cox-Snell residual plot...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28176232/celiac-disease-in-children-with-severe-acute-malnutrition-sam-a-hospital-based-study
#5
Neetu Beniwal, Gaurav Ameta, Chandra Kumar Chahar
OBJECTIVES: To evaluate the prevalence and clinical features of Celiac disease among children with severe acute malnutrition (SAM). METHODS: This prospective observational study was conducted in PBM Children Hospital, Bikaner from July 2012 through December 2013. All consecutively admitted children with SAM were recruited. All subjects were screened for Celiac disease by serological test for IgA-anti tissue Transglutaminase (IgA tTG) antibodies. All seropositive children underwent upper gastrointestinal endoscopy for small bowel biopsy for the confirmation...
February 8, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28166247/recovery-rate-and-associated-factors-of-children-age-6-to-59-months-admitted-with-severe-acute-malnutrition-at-inpatient-unit-of-bahir-dar-felege-hiwot-referral-hospital-therapeutic-feeding-unite-northwest-ethiopia
#6
Hanna Demelash Desyibelew, Abel Fekadu, Haile Woldie
BACKGROUND: Despite numerous advances made in improving child health and the clinical management protocols for treating severe acute malnutrition at treatment centers, evidences concerning the treatment outcomes are scarce. Therefore, this study was conducted to assess the recovery rate and associated factors of severely acute malnourished children of age 6 to 59 months admitted to inpatient therapeutic feeding unit at Felege Hiwot Referral Hospital. METHODS: We conducted a hospital-based cross-sectional study including 401 severely malnourished children who were admitted from September 2012 to January 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28164028/the-clinical-spectrum-of-severe-acute-malnutrition-in-children-in-cameroon-a-hospital-based-study-in-yaounde-cameroon
#7
Andreas Chiabi, Berthe Malangue, Seraphin Nguefack, Félicitée Nguefack Dongmo, Florence Fru, Virginie Takou, Fru Angwafo
BACKGROUND: Severe acute malnutrition (SAM) is a major health problem, and the cause of more than half of childhood deaths in children less than 5 years in developing countries. Globally, 20 million children under 5 years of age are severely malnourished according to the World Health Organization (WHO). In Cameroon, the prevalence of SAM remains high and estimated at 1.9% in 2011 and 1.3% in 2014. The aim of this study was to determine the epidemiology, clinical aspects and outcome of SAM at the Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH)...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28162141/child-maternal-and-household-level-correlates-of-nutritional-status-a-cross-sectional-study-among-young-samoan-children
#8
Courtney C Choy, Mayur M Desai, Jennifer J Park, Elizabeth A Frame, Avery A Thompson, Take Naseri, Muagututia S Reupena, Rachel L Duckham, Nicole C Deziel, Nicola L Hawley
OBJECTIVE: Young children are particularly vulnerable to malnutrition as nutrition transition progresses. The present study aimed to document the prevalence, coexistence and correlates of nutritional status (stunting, overweight/obesity and anaemia) in Samoan children aged 24-59 months. DESIGN: A cross-sectional community-based survey. Height and weight were used to determine prevalence of stunting (height-for-age Z-score +2) based on WHO growth standards. Anaemia was determined using an AimStrip Hemoglobin test system (Hb <110 g/l)...
February 6, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28148680/the-plasma-proteome-is-associated-with-anthropometric-status-of-undernourished-nepalese-school-aged-children
#9
Sun Eun Lee, Christine P Stewart, Kerry J Schulze, Robert N Cole, Lee S-F Wu, James D Yager, John D Groopman, Subarna K Khatry, Ramesh Kant Adhikari, Parul Christian, Keith P West
BACKGROUND: Malnutrition affects body growth, size, and composition of children. Yet, few functional biomarkers are known to be associated with childhood morphology. OBJECTIVE: This cross-sectional study examined associations of anthropometric indicators of height, musculature, and fat mass with plasma proteins by using proteomics in a population cohort of school-aged Nepalese children. METHODS: Height, weight, midupper arm circumference (MUAC), triceps and subscapular skinfolds, upper arm muscle area (AMA), and arm fat area (AFA) were assessed in 500 children 6-8 y of age...
February 1, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28125907/acceptability-and-efficacy-of-locally-produced-ready-to-use-therapeutic-food-nutreal-in-the-management-of-severe-acute-malnutrition-in-comparison-with-defined-food
#10
Babu Ram Thapa, Pooja Goyal, Jagadeesh Menon, Ajay Sharma
BACKGROUND: Severe acute malnutrition (SAM) is a salient health problem in India. Federation of Indian Chamber of Commerce and Industry (FICCI) Research and Analysis Centre, New Delhi, prepared nutreal equivalent to ready-to-use therapeutic food by World Health Organization (WHO) for the management of SAM and defined food like homemade diet. OBJECTIVE: To compare acceptability and efficacy of nutreal over defined food for the management of SAM. METHODS: One hundred twelve children aged less than 5 years with SAM were enrolled as per the standard of WHO...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28122629/bacteremia-caused-by-multidrug-resistant-bacteria-among-hospitalized-malnourished-children-in-mwanza-tanzania-a-cross-sectional-study
#11
Maimuna Ahmed, Mariam M Mirambo, Martha F Mushi, Adolfine Hokororo, Stephen E Mshana
BACKGROUND: Severe malnutrition has been known to increase susceptibility and severity of infections. Bacteremia in malnourished children has been found to increase morbidity and mortality especially if is due to multidrug resistant bacteria. Here, we report the prevalence of bacteremia among children under 5 years of age and the antibiotic susceptibility pattern of the isolates; the information that can be used by clinicians to guide on the empirical antibiotic treatment. FINDINGS: A total of 402 malnourished children were investigated for bacteremia...
January 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28115034/using-cross-sectional-surveys-to-estimate-the-number-of-severely-malnourished-children-needing-to-be-enrolled-in-specific-treatment-programmes
#12
Nancy M Dale, Mark Myatt, Claudine Prudhon, André Briend
OBJECTIVE: When planning severe acute malnutrition (SAM) treatment services, estimates of the number of children requiring treatment are needed. Prevalence surveys, used with population estimates, can directly estimate the number of prevalent cases but not the number of subsequent incident cases. Health managers often use a prevalence-to-incidence conversion factor (J) derived from two African cohort studies to estimate incidence and add the expected number of incident cases to prevalent cases to estimate expected SAM caseload for a given period...
January 24, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28090471/hair-zinc-level-analysis-and-correlative-micronutrients-in-children-presenting-with-malnutrition-and-poor-growth
#13
Tae Hwan Han, Jin Lee, Yong Joo Kim
PURPOSE: Zinc deficiency can induce serious clinical problems in the gastrointestinal (GI) system and immune system and can affect growth and development. It is more severe in younger patients. Chronic zinc deficiency is reflected more precisely in hair than in serum. We studied hair zinc levels and other hair and serum micronutrients in chronic malnourished children to identify which micronutrients are affected or correlated with the other ones. METHODS: Hair mineral analyses were performed in 56 children (age, 1-15 years) presenting with malnutrition, poor growth, poor appetite, anorexia, with/without other GI symptoms (diarrhea, abdominal pain, constipation) from August 2012 to March 2015...
December 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28079729/effect-of-probiotics-on-diarrhea-in-children-with-severe-acute-malnutrition-a-randomized-controlled-study-in-uganda
#14
Benedikte Grenov, Hanifa Namusoke, Betty Lanyero, Nicolette Nabukeera-Barungi, Christian Ritz, Christian Mølgaard, Henrik Friis, Kim F Michaelsen
OBJECTIVES: To assess the effect of probiotics on diarrhea during in- and outpatient treatment of children with severe acute malnutrition (SAM). METHODS: A randomized, double-blind, placebo-controlled study was conducted involving 400 children admitted with SAM. Patients received one daily dose of a blend of Bifidobacterium animalis subsp. lactis (BB-12) and Lactobacillus rhamnosus (LGG) (10 billion colony-forming units, 50:50) or placebo during hospitalization followed by an 8-12 week outpatient treatment period, depending on patients' recovery rate...
January 11, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28077108/wasting-underweight-and-stunting-among-children-with-congenital-heart-disease-presenting-at-mulago-hospital-uganda
#15
Anthony Batte, Peter Lwabi, Sulaiman Lubega, Sarah Kiguli, Kennedy Otwombe, Lucy Chimoyi, Violette Nabatte, Charles Karamagi
BACKGROUND: Children with congenital heart disease are at increased risk of malnutrition. The aim of this study was to describe the prevalence of wasting, underweight and stunting among children with congenital heart disease attending Mulago National Referral Hospital, Uganda. METHODS: A cross-sectional study among 194 children aged 0-15 years was conducted between August 2013 and March 2014. Anthropometric measurements and clinical assessments were carried out on all children...
January 11, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28068960/nutritional-status-among-primary-school-children-in-rural-sri-lanka-a-public-health-challenge-for-a-country-with-high-child-health-standards
#16
N P G C R Naotunna, M Dayarathna, H Maheshi, G S Amarasinghe, V S Kithmini, M Rathnayaka, L Premachandra, N Premarathna, P C Rajasinghe, G Wijewardana, T C Agampodi, S B Agampodi
BACKGROUND: Nutritional status of pre adolescent children is not widely studied in Sri Lanka. The purpose of this study was to determine the nutritional status among pre-adolescent school children in a rural province of Sri Lanka. METHODS: A school based cross sectional study was carried out in North Central Province in 100 rural schools, selected using multi stage cluster sampling with probability proportionate to size. Children in grade one to five were enrolled with a maximum cluster size of fifty...
January 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28052519/efficacy-of-world-health-organization-guideline-in-facility-based-reduction-of-mortality-in-severely-malnourished-children-from-low-and-middle-income-countries-a-systematic-review-and-meta-analysis
#17
Muttaquina Hossain, Mohammod J Chisti, Mohammod Iqbal Hossain, Mustafa Mahfuz, Mohammad Munirul Islam, Tahmeed Ahmed
AIM: Globally more than 19 million under-five children suffer from severe acute malnutrition (SAM). Data on efficacy of World Health Organization's (WHO's) guideline in reducing SAM mortality are limited. We aimed to assess the efficacy of WHO's facility-based guideline for the reduction of under-five SAM children mortality from low and middle income countries (LMICs). METHODS: A systematic search of literature published in 1980-2015 was conducted using electronic databases...
January 4, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28031190/risk-factors-for-death-in-children-during-inpatient-treatment-of-severe-acute-malnutrition-a-prospective-cohort-study
#18
Maren Jh Rytter, Esther Babirekere-Iriso, Hanifa Namusoke, Vibeke B Christensen, Kim F Michaelsen, Christian Ritz, Charlotte G Mortensen, Ezekiel Mupere, Henrik Friis
BACKGROUND: Children who receive in-hospital treatment of severe acute malnutrition often have high mortality rates, and the reasons are not well understood. OBJECTIVE: We assessed risk factors for death in children who were treated for malnutrition in a hospital. DESIGN: In a prospective observational study of 120 children who were receiving in-hospital treatment of severe acute malnutrition in Uganda with therapeutic formulas F-75 and F-100, we collected data on symptoms, clinical findings, plasma markers of refeeding syndrome (electrolytes and phosphate), and acute phase reactants, and recorded the nutritional therapy given in hospital...
December 28, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28030608/predicting-hospitalised-paediatric-pneumonia-mortality-risk-an-external-validation-of-risc-and-mrisc-and-local-tool-development-risc-malawi-from-malawi
#19
Shubhada Hooli, Tim Colbourn, Norman Lufesi, Anthony Costello, Bejoy Nambiar, Satid Thammasitboon, Charles Makwenda, Charles Mwansambo, Eric D McCollum, Carina King
BACKGROUND: Pneumonia is the leading infectious cause of under-5 mortality in sub-Saharan Africa. Clinical prediction tools may aide case classification, triage, and allocation of hospital resources. We performed an external validation of two published prediction tools and compared this to a locally developed tool to identify children admitted with pneumonia at increased risk for in-hospital mortality in Malawi. METHODS: We retrospectively analyzed the performance of the Respiratory Index of Severity in Children (RISC) and modified RISC (mRISC) scores in a child pneumonia dataset prospectively collected during routine care at seven hospitals in Malawi between 2011-2014...
2016: PloS One
https://www.readbyqxmd.com/read/28027633/pancreatic-exocrine-insufficiency-in-malnourished-children-and-those-with-persistent-diarrhoeae
#20
Ariani Dewi Widodo, Ina S Timan, Saptawati Bardosono, Widdy Winarta, Dwi Prasetyo, Agus Firmansyah
BACKGROUND AND OBJECTIVES: Persistent diarrhoea, a serious health problem, is closely related to malnutrition. Children with severe malnutrition have a 9-fold risk of death, and children with severe stunting have a 4-fold risk of death. Prolonged mucosal injury from diarrhoea causes reduced secretin and cholecystokinin secretion, which decreases stimulation to the pancreas, and is indicated by faecal elastase-1 levels. This further aggravates persistent diarrhoea and malnutrition because of the low levels of digestive enzyme production...
December 2016: Asia Pacific Journal of Clinical Nutrition
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