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https://www.readbyqxmd.com/read/29779813/negative-role-of-malnutrition-in-cell-mediated-immune-response-pneumocystis-jirovecii-pneumonia-pcp-in-a-severely-malnourished-hiv-negative-patient-with-anorexia-nervosa
#1
Mouna Hanachi, Vanessa Bohem, Pauline Bemer, Nadja Kayser, Pierre de Truchis, Jean-Claude Melchior
It is generally acknowledged that malnutrition is a propensity factor for secondary infections in different clinical situations (malnutrition-associated infections in hospitalized patients and malnourished children in developing countries). However, it is not clear how malnutrition might facilitate the development of opportunistic infections in human immunodeficiency virus (HIV)-negative patients without a definite etiology (disease or treatment) of impaired cell-mediated immune response. We report here on a case of Pneumocystis jirovecii pneumonia in an HIV-negative patient suffering from anorexia nervosa with extreme malnutrition, which had a favorable outcome despite the severity of her respiratory failure...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29771994/prevalence-outcome-and-quality-of-care-among-children-hospitalized-with-severe-acute-malnutrition-in-kenyan-hospitals-a-multi-site-observational-study
#2
Susan Gachau, Grace Irimu, Philip Ayieko, Samuel Akech, Ambrose Agweyu, Mike English
BACKGROUND: Severe acute malnutrition (SAM) remains a major cause of admission and inpatient mortality worldwide in children aged less than 5 years. In this study, we explored SAM prevalence and outcomes in children admitted in 13 Kenyan hospitals participating in a Clinical Information Network (CIN). We also describe their immediate in-patient management. METHODS: We analyzed data for children aged 1-59 months collected retrospectively from medical records after discharge...
2018: PloS One
https://www.readbyqxmd.com/read/29756960/socio-demographic-variables-and-underlying-pathologies-associated-to-nutritional-status-of-hospitalized-children-in-a-secondary-tertiary-level-hospital
#3
Nelly Carolina Muñoz Esparza, Edgar Manuel Vasquez-Garibay, Alfredo Larrosa-Haro, Enrique Romero-Velarde
OBJECTIVE: the purpose was to evaluate the nutritional status in hospitalized children according to their socio-demographic variables, underlying pathology and based on hospital length of stay. METHODS: seven-hundred and sixty-three hospitalized patients of the Civil Hospital of Guadalajara Dr. Juan I. Menchaca were included in a cross-sectional study. The following anthropometric indices were taken: weight/length, weight/height, weight/age, length/age, height/age, head circumference/age and BMI/age...
February 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29749331/colonoscopic-decompression-of-childhood-sigmoid-and-cecal-volvulus
#4
Iraj Shahramian, Ali Bazil, Danial Ebadati, Karim Rostami, Mojtaba Delaramnasab
Cases of colonic volvulus in children are infrequently described in the literature. Here we describe the case of three patients with colonic volvulus. The first patient was a 10-year-old girl with abdominal dilation and pain and no bowel movement for 48 h. Her abdominal X-ray showed the coffee bean sign adjacent to the diaphragm, which was compatible with a diagnosis of cecal volvulus. The second patient was a 4-year-old boy with a history of chronic constipation during the past year and with no bowel movement for 24 h...
March 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29746496/pharyngeal-colonization-and-drug-resistance-profiles-of-morraxella-catarrrhalis-streptococcus-pneumoniae-staphylococcus-aureus-and-haemophilus-influenzae-among-hiv-infected-children-attending-art-clinic-of-felegehiwot-referral-hospital-ethiopia
#5
Wondemagegn Mulu, Endalew Yizengaw, Megbaru Alemu, Daniel Mekonnen, Derese Hailu, Kassaw Ketemaw, Bayeh Abera, Mulugeta Kibret
BACKGROUND: Asymptomatic pharyngeal colonization by potential bacteria is the primary reservoir for bacterial species within a population and is considered a prerequisite for development of major childhood diseases such as sinusitis, otitis media, pneumonia, bacteremia, and meningitis. However, there is dearth of data on the colonization and drug resistance pattern of the main bacterial pathogens in the pharynx of HIV infected children in Ethiopia. Therefore, this study determined the pharyngeal colonization and drug resistance profile of bacterial pathogens in HIV infected children attending ART clinic of Felegehiwot Referral Hospital (FHRH), Amhara Region, Ethiopia...
2018: PloS One
https://www.readbyqxmd.com/read/29740973/findings-from-a-cluster-randomised-trial-of-unconditional-cash-transfers-in-niger
#6
Victoria L Sibson, Carlos S Grijalva-Eternod, Garba Noura, Julia Lewis, Kwanli Kladstrup, Hassan Haghparast-Bidgoli, Jolene Skordis-Worrall, Tim Colbourn, Joanna Morrison, Andrew J Seal
Unconditional cash transfers (UCTs) are used as a humanitarian intervention to prevent acute malnutrition, despite a lack of evidence about their effectiveness. In Niger, UCT and supplementary feeding are given during the June-September "lean season," although admissions of malnourished children to feeding programmes may rise from March/April. We hypothesised that earlier initiation of the UCT would reduce the prevalence of global acute malnutrition (GAM) in children 6-59 months old in beneficiary households and at population level...
May 8, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29736993/children-with-cerebral-palsy-in-ghana-malnutrition-feeding-challenges-and-caregiver-quality-of-life
#7
Sarah Polack, Mel Adams, David O'banion, Marjolein Baltussen, Sandra Asante, Marko Kerac, Melissa Gladstone, Maria Zuurmond
AIM: To assess feeding difficulties and nutritional status among children with cerebral palsy (CP) in Ghana, and whether severity of feeding difficulties and malnutrition are independently associated with caregiver quality of life (QoL). METHOD: This cross-sectional survey included 76 children with CP (18mo-12y) from four regions of Ghana. Severity of CP was classified using the Gross Motor Function Classification System and anthropometric measures were taken. Caregivers rated their QoL (using the Pediatric Quality of Life Inventory Family Impact Module) and difficulties with eight aspects of child feeding...
May 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29732931/determinants-of-the-global-prices-of-ready-to-use-therapeutic-foods
#8
Jakub Kakietek
BACKGROUND: A therapy based on ready-to-use therapeutic food (RUTF) in outpatient settings is considered the gold standard in the treatment of severe acute malnutrition in children younger than 5 years. The price of RUTF is the key cost driver of the therapy. However, no studies to date have systematically examined the determinants of RUTF prices. OBJECTIVE: This article presents the first analysis of factors associated with the prices of RUTF, focusing on the impact of competition and tendering...
January 1, 2018: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/29726948/children-with-poor-linear-growth-are-at-risk-for-repeated-relapse-to-wasting-after-recovery-from-moderate-acute-malnutrition
#9
Heather C Stobaugh, Beatrice L Rogers, Irwin H Rosenberg, Patrick Webb, Kenneth M Maleta, Mark J Manary, Indi Trehan
Background: Nutrition programs frequently approach wasting and stunting as 2 separate conditions with distinct causes and effects. Although several cross-sectional studies have identified an association between the 2 conditions, longitudinal studies are useful to quantify the risk of acute malnutrition based on the trajectory of linear growth. Objective: We analyzed data from a longitudinal study to explore associations between linear growth and relapse to acute malnutrition in high-risk children during the year after recovery from moderate acute malnutrition (MAM)...
May 3, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29722846/high-dose-vitamin-d3-in-the-treatment-of-severe-acute-malnutrition-a-multicenter-double-blind-randomized-controlled-trial
#10
Javeria Saleem, Rubeena Zakar, Muhammad Z Zakar, Mulugeta Belay, Marion Rowe, Peter M Timms, Robert Scragg, Adrian R Martineau
Background: Vitamin D deficiency is common in children with severe acute malnutrition, in whom it is associated with severe wasting. Ready-to-use therapeutic food (the standard treatment) contains modest amounts of vitamin D that do not reliably correct deficiency. Objective: The aim of this study was to determine whether high-dose oral vitamin D3 enhances weight gain and development in children with uncomplicated severe acute malnutrition. Design: We conducted a randomized placebo-controlled trial of high-dose vitamin D3 supplementation in children aged 6-58 mo with uncomplicated severe acute malnutrition in Pakistan...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29715324/correction-characterizing-the-metabolic-phenotype-of-intestinal-villus-blunting-in-zambian-children-with-severe-acute-malnutrition-and-persistent-diarrhea
#11
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0192092.].
2018: PloS One
https://www.readbyqxmd.com/read/29701632/household-food-insecurity-as-a-predictor-of-stunted-children-and-overweight-obese-mothers-scowt-in-urban-indonesia
#12
Trias Mahmudiono, Triska Susila Nindya, Dini Ririn Andrias, Hario Megatsari, Richard R Rosenkranz
(1) Background : The double burden of malnutrition has been increasing in countries experiencing the nutrition transition. This study aimed to determine the relationship between household food insecurity and the double burden of malnutrition, defined as within-household stunted child and an overweight/obese mother (SCOWT). (2) Methods : A cross-sectional survey was conducted in the urban city of Surabaya, Indonesia in April and May 2015. (3) Results : The prevalence of child stunting in urban Surabaya was 36...
April 26, 2018: Nutrients
https://www.readbyqxmd.com/read/29693557/continuous-glucose-monitoring-in-resource-constrained-settings-for-hypoglycaemia-detection-looking-at-the-problem-from-the-other-side-of-the-coin
#13
Rubao Bila, Rosauro Varo, Lola Madrid, Antonio Sitoe, Quique Bassat
The appearance, over a decade ago, of continuous glucose monitoring (CGM) devices has triggered a patient-centred revolution in the control and management of diabetes mellitus and other metabolic conditions, improving the patient’s glycaemic control and quality of life. Such devices, the use of which remains typically restricted to high-income countries on account of their elevated costs, at present show very limited implantation in resource-constrained settings, where many other urgent health priorities beyond diabetes prevention and management still need to be resolved...
April 25, 2018: Biosensors
https://www.readbyqxmd.com/read/29692662/changes-in-the-chemical-composition-of-mineralised-teeth-in-children-after-antineoplastic-treatment
#14
Ewa Krasuska-Sławińska, Bożenna Dembowska-Bagińska, Agnieszka Brożyna, Dorota Olczak-Kowalczyk, Elżbieta Czarnowska, Agnieszka Sowińska
Introduction: Chemotherapy, neoplasms, and their complications linked to malabsorption, malnutrition, and metabolic disorders may lead to improper tooth development and frequent severe caries in patients during/after antineoplastic treatment and to a more frequent improper tooth development in patients undergoing chemotherapy during odontogenesis. However, the causes of these abnormalities remain unknown; there are no studies on the impact of antineoplastic treatment and its complications on the chemical composition of mineralised teeth...
2018: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29690916/combined-protocol-for-acute-malnutrition-study-compas-in-rural-south-sudan-and-urban-kenya-study-protocol-for-a-randomized-controlled-trial
#15
Jeanette Bailey, Natasha Lelijveld, Bethany Marron, Pamela Onyoo, Lara S Ho, Mark Manary, André Briend, Charles Opondo, Marko Kerac
BACKGROUND: Acute malnutrition is a continuum condition, but severe and moderate forms are treated separately, with different protocols and therapeutic products, managed by separate United Nations agencies. The Combined Protocol for Acute Malnutrition Study (ComPAS) aims to simplify and unify the treatment of uncomplicated severe and moderate acute malnutrition (SAM and MAM) for children 6-59 months into one protocol in order to improve the global coverage, quality, continuity of care and cost-effectiveness of acute malnutrition treatment in resource-constrained settings...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29688090/high-and-low-body-mass-index-may-predict-severe-disease-course-in-children-with-inflammatory-bowel-disease
#16
Anat Yerushalmy-Feler, Amir Ben-Tov, Yael Weintraub, Achiya Amir, Tut Galai, Hadar Moran-Lev, Shlomi Cohen
OBJECTIVES: Inflammatory bowel disease (IBD) has been historically associated with underweight and malnutrition. The impact of both underweight and obesity on the clinical course of IBD in adults is controversial. This study described the association between body mass index (BMI) at diagnosis to disease course in children with IBD. METHODS: We reviewed the medical records of children with IBD from the database of the 'Dana-Dwek' Children's Hospital between 2010 and 2016...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29678205/management-of-severe-acute-malnutrition-by-cow-milk-in-resource-constraints-settings-experience-of-the-nutritional-centre-of-the-university-clinics-of-graben
#17
Mupenzi Mumbere, F Katsuva Mbahweka, B P Furaha Nzanzu
BACKGROUND: Severe acute malnutrition is defined as a weight for height z-score < - 3 standard deviation. Since 2000, joint efforts of the World Health Organization and United Nations Children's Fund allowed to standardize the management of acute malnutrition by improving outcome and preventing complications with the introduction of therapeutic milk and ready-to-use therapeutic foods. However, in the Democratic Republic of Congo, many health facilities face therapeutic milk shortage while managing severe acute malnutrition...
April 20, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29670006/diets-and-feeding-practices-during-the-first-1000-days-window-in-the-phnom-penh-and-north-eastern-districts-of-cambodia
#18
Somphos Vicheth Som, Sophonneary Prak, Arnaud Laillou, Ludovic Gauthier, Jacques Berger, Etienne Poirot, Frank T Wieringa
Although several health and development indicators have improved significantly in Cambodia, inadequate breastfeeding and inappropriate complementary feeding practices leave many children at high risk of malnutrition during the early stages of life. In 2014, the prevalence of wasting and stunting among Cambodian children under 5 were 10% and 32%, respectively. Thus, a strong focus on improving feeding practices within the first 1000 days window to reduce child malnutrition prevalence in Cambodia is needed. This cross-sectional study assessed the current feeding practices among of women of reproductive age, pregnant women, lactating women and children less than 24 months living in six districts from Phnom Penh and two rural provinces in the North East of Cambodia...
April 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29667569/ethnic-and-age-differences-in-prediction-of-mortality-by-mid-upper-arm-circumference-in-children-below-3-years-of-age-in-nepal
#19
Avni Gupta, James M Tielsch, Subarna K Khatry, Steven C LeClerq, Luke C Mullany, Joanne Katz
OBJECTIVE: To assess ethnicity- and age-modified associations between mid-upper arm circumference (MUAC) and mortality in Nepalese children and whether sociodemographic factors explain these associations. DESIGN: Secondary data analysis of children followed until 3 years of age. Estimated mortality hazard ratios (HR) for MUAC<11·5cm (recommended cut-off for identifying severe acute malnutrition among children ≥6 months old) compared with ≥11·5cm in younger (<6 months) and older children (≥6 months) of Pahadi and Madhesi ethnicity, adjusting for sex, socio-economic status (SES) and mother's education using Cox proportional hazard models...
April 18, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29658318/what-makes-children-with-cerebral-palsy-vulnerable-to-malnutrition-findings-from-the-bangladesh-cerebral-palsy-register-bcpr
#20
Israt Jahan, Mohammad Muhit, Tasneem Karim, Hayley Smithers-Sheedy, Iona Novak, Cheryl Jones, Nadia Badawi, Gulam Khandaker
PURPOSE: To assess the nutritional status and underlying risk factors for malnutrition among children with cerebral palsy in rural Bangladesh. MATERIALS AND METHODS: We used data from the Bangladesh Cerebral Palsy Register; a prospective population based surveillance of children with cerebral palsy aged 0-18 years in a rural subdistrict of Bangladesh (i.e., Shahjadpur). Socio-demographic, clinical and anthropometric measurements were collected using Bangladesh Cerebral Palsy Register record form...
April 16, 2018: Disability and Rehabilitation
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