keyword
MENU ▼
Read by QxMD icon Read
search

Chd epidemiology

keyword
https://www.readbyqxmd.com/read/28196953/prevalence-and-patterns-of-congenital-heart-diseases-in-africa-a-systematic-review-and-meta-analysis-protocol
#1
Aurel T Tankeu, Jean Joel R Bigna, Jobert Richie N Nansseu, Leopold Ndemnge Aminde, Celestin Danwang, Mazou N Temgoua, Jean Jacques N Noubiap
INTRODUCTION: Congenital heart diseases (CHD) are common causes of cardiovascular morbidity and mortality among young children and adolescents living in Africa. Accurate epidemiological data are needed in order to evaluate and improve preventive strategies. This review aims to determine the prevalence of CHD and their main patterns in Africa. METHODS AND ANALYSIS: This systematic review and meta-analysis will include cross-sectional, case-control and cohort studies of populations residing inside African countries, which have reported the prevalence of CHD, confirmed by an echocardiographic examination and/or describing different patterns of these abnormalities in Africa...
February 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28189076/depression-social-support-and-long-term-risk-for-coronary-heart-disease-in-a-13-year-longitudinal-epidemiological-study
#2
Richard T Liu, Evelyn M Hernandez, Zoë M Trout, Evan M Kleiman, Melanie L Bozzay
Depression has been linked with long-term risk for a variety of physical health ailments, including coronary heart disease (CHD). Little is known about resilience factors that may attenuate this relationship. The current study assessed whether social support moderates the long-term risk for CHD associated with this disorder. Data were drawn from the Americans' Changing Lives study, a nationally representative longitudinal survey of adults in the United States. Participants (unweighted n=1636) completed initial assessments of functional social support, body mass index, recent history of major depression, CHD, hypertension, and diabetes...
February 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28181463/reproducibility-of-an-extensive-self-report-questionnaire-used-in-secondary-coronary-prevention
#3
Kari Peersen, John Munkhaugen, Lars Gullestad, Toril Dammen, Torbjorn Moum, Jan Erik Otterstad
AIMS: Self-reported information from questionnaires is frequently used in clinical epidemiological studies, but few provide information on the reproducibility of instruments applied in secondary coronary prevention studies. This study aims to assess the test-retest reproducibility of the questionnaire applied in the cross-sectional NORwegian CORonary (NOR-COR) Prevention Study. METHODS: In the NOR-COR study 1127 coronary heart disease (CHD) patients completed a self-report questionnaire consisting of 249 questions, of which there are both validated instruments and de novo questions...
January 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28135244/genome-wide-association-analysis-identifies-novel-blood-pressure-loci-and-offers-biological-insights-into-cardiovascular-risk
#4
Helen R Warren, Evangelos Evangelou, Claudia P Cabrera, He Gao, Meixia Ren, Borbala Mifsud, Ioanna Ntalla, Praveen Surendran, Chunyu Liu, James P Cook, Aldi T Kraja, Fotios Drenos, Marie Loh, Niek Verweij, Jonathan Marten, Ibrahim Karaman, Marcelo P Segura Lepe, Paul F O'Reilly, Joanne Knight, Harold Snieder, Norihiro Kato, Jiang He, E Shyong Tai, M Abdullah Said, David Porteous, Maris Alver, Neil Poulter, Martin Farrall, Ron T Gansevoort, Sandosh Padmanabhan, Reedik Mägi, Alice Stanton, John Connell, Stephan J L Bakker, Andres Metspalu, Denis C Shields, Simon Thom, Morris Brown, Peter Sever, Tõnu Esko, Caroline Hayward, Pim van der Harst, Danish Saleheen, Rajiv Chowdhury, John C Chambers, Daniel I Chasman, Aravinda Chakravarti, Christopher Newton-Cheh, Cecilia M Lindgren, Daniel Levy, Jaspal S Kooner, Bernard Keavney, Maciej Tomaszewski, Nilesh J Samani, Joanna M M Howson, Martin D Tobin, Patricia B Munroe, Georg B Ehret, Louise V Wain
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) among UK Biobank participants of European ancestry with independent replication in other cohorts, and robust validation of 107 independent loci. We also identify new independent variants at 11 previously reported blood pressure loci. In combination with results from a range of in silico functional analyses and wet bench experiments, our findings highlight new biological pathways for blood pressure regulation enriched for genes expressed in vascular tissues and identify potential therapeutic targets for hypertension...
January 30, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28126509/-cardiac-rehabilitation-for-children-and-adults-with-congenital-heart-disease
#5
Pascal Amedro, Arthur Gavotto, Charlène Bredy, Sophie Guillaumont
Advances in heart surgery over the past 30 years have significantly improved the prognosis of congenital heart diseases (CHD). Therefore, the epidemiology of CHD has changed dramatically with a shift of mortality from pediatrics to adulthood and an increased prevalence of complex CHD. Today, caregivers and patients focus their interests to new perspectives: improving the quality of life, practicing sports, improving psychosocial care. Cardiac rehabilitation is completely integrated in these new therapeutic strategies...
January 23, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28125802/saturated-fat-consumption-and-risk-of-coronary-heart-disease-and-ischemic-stroke-a-science-update
#6
Joyce A Nettleton, Ingeborg A Brouwer, Johanna M Geleijnse, Gerard Hornstra
At a workshop to update the science linking saturated fatty acid (SAFA) consumption with the risk of coronary heart disease (CHD) and ischemic stroke, invited participants presented data on the consumption and bioavailability of SAFA and their functions in the body and food technology. Epidemiological methods and outcomes were related to the association between SAFA consumption and disease events and mortality. Participants reviewed the effects of SAFA on CHD, causal risk factors, and surrogate risk markers...
January 27, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28086762/prevalence-and-risk-factors-of-congenital-heart-defects-among-live-births-a-population-based-cross-sectional-survey-in-shaanxi-province-northwestern-china
#7
Leilei Pei, Yijun Kang, Yaling Zhao, Hong Yan
BACKGROUND: Nearly half of the population of Northwest China live in Shaanxi province, but population-based data on the epidemiologic characteristics of congenital heart defects (CHD) in this population is limited. The study aimed to investigate the prevalence and epidemiologic characteristics of the CHD among infants born between 2010 and 2013 in Shaanxi province. METHODS: Infants born between 2010 and 2013 in Shaanxi province were surveyed using a stratified multi-stage sampling method...
January 13, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28057253/hiv-and-ischemic-heart-disease
#8
REVIEW
Ahmed Vachiat, Keir McCutcheon, Nqoba Tsabedze, Don Zachariah, Pravin Manga
The association of coronary heart disease (CHD) and human immunodeficiency virus (HIV) infection has been well recognized for many years. The etiology of the increased prevalence of CHD in HIV-infected populations is the result of complex interactions among the viral infection, host factors, traditional risk factors, and therapies for HIV. As the HIV population is living longer, largely attributable to combination antiretroviral therapy, there is concern about the effect of the rising prevalence of CHD on morbidity and mortality, as well its effect on health systems around the world...
January 3, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28054441/dietary-total-flavonoids-intake-and-risk-of-mortality-from-all-causes-and-cardiovascular-disease-in-the-general-population-a-systematic-review-and-meta-analysis-of-cohort-studies
#9
REVIEW
Xue-Ming Liu, Yu-Jian Liu, Yao Huang, Hong-Jie Yu, Shuai Yuan, Bo-Wen Tang, Pei-Gang Wang, Qi-Qiang He
AIM: Epidemiologic studies assessing the association between dietary total flavonoids intake and the risk of mortality from cardiovascular disease (CVD) and all causes have yielded inconsistent results. Therefore, we conducted a dose-response meta-analysis to investigate this association. METHOD: We searched PubMed and Embase databases from January 1966 through May 2016 and examined the references of retrieved articles to identify relevant prospective cohort studies...
January 5, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28051024/association-of-chronic-kidney-disease-with-coronary-heart-disease-and-stroke-risks-in-patients-with-type-2-diabetes-mellitus-an-observational-cross-sectional-study-in-hangzhou-china
#10
Xue Sun, Jie He, Xiao-Li Ji, Yi-Ming Zhao, Han-Yu Lou, Xiao-Xiao Song, Li-Zhen Shan, Ying-Xiu Kang, Wen-Heng Zeng, Xiao-Hong Pang, Song-Zhao Zhang, Yue Ding, Yue-Zhong Ren, Peng-Fei Shan
BACKGROUND: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD). However, the association between CKD and CVD risk in patients with type 2 diabetes mellitus (T2DM) in China has not yet been well investigated. This study aimed to determine the association of CKD with the risks of coronary heart disease (CHD) and stroke in a Chinese population with T2DM. METHODS: A total of 1401 inpatients with T2DM at the Second Affiliated Hospital of Zhejiang University School of Medicine between April 2008 and November 2013 were included in this study...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28035059/significant-association-between-functional-microrna-polymorphisms-and-coronary-heart-disease-susceptibility-a-comprehensive-meta-analysis-involving-16484-subjects
#11
Xu Liu, Lianghao You, Ruizhi Zhou, Jian Zhang
Molecular epidemiological studies suggest that microRNA polymorphisms may be associated with an increased risk of coronary heart disease (CHD). However, the results of these studies were inconsistent and inconclusive. To derive a more precise evaluation, we performed a meta-analysis focused on the associations between microRNA polymorphisms and CHD risk. PubMed, Embase, CNKI and Wanfang databases were searched. Odds ratios (ORs) with 95% confidence intervals (CIs) were applied to assess the association between microRNA-146a rs2910164, microRNA-196a2 rs11614913, microRNA-499 rs3746444 and microRNA-149 rs71428439 polymorphisms and CHD susceptibility...
January 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28002548/absolute-rates-of-heart-failure-coronary-heart-disease-and-stroke-in-chronic-kidney-disease-an-analysis-of-3-community-based-cohort-studies
#12
Nisha Bansal, Ronit Katz, Cassianne Robinson-Cohen, Michelle C Odden, Lorien Dalrymple, Michael G Shlipak, Mark J Sarnak, David S Siscovick, Leila Zelnick, Bruce M Psaty, Bryan Kestenbaum, Adolfo Correa, Maryam Afkarian, Bessie Young, Ian H de Boer
Importance: Cardiovascular disease is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). Understanding the relative contributions of cardiovascular disease event types to the excess burden of cardiovascular disease is important for developing effective strategies to improve outcomes. Objective: To determine absolute rates and risk differences of incident heart failure (HF), coronary heart disease (CHD), and stroke in participants with vs without CKD...
December 21, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27990414/what-is-new-in-genetics-of-congenital-heart-defects
#13
REVIEW
Maria Cristina Digilio, Bruno Marino
Epidemiological studies, clinical observations, and advances in molecular genetics are contributing to the understanding of the etiology of congenital heart defects (CHDs). Several phenotype-genotype correlation studies have suggested that specific morphogenetic mechanisms put in motion by genes can result in a specific cardiac phenotype. The use of new technologies has increased the possibility of identification of new genes and chromosomal loci in syndromic and non-syndromic CHDs. There are a number of methods available for genetic research studies of CHDs, including cytogenetic analysis, linkage and association studies, copy number variation (CNV) and DNA micro-array analysis, and whole exome sequencing...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27940953/genetic-invalidation-of-lp-pla2-as-a-therapeutic-target-large-scale-study-of-five-functional-lp-pla2-lowering-alleles
#14
John M Gregson, Daniel F Freitag, Praveen Surendran, Nathan O Stitziel, Rajiv Chowdhury, Stephen Burgess, Stephen Kaptoge, Pei Gao, James R Staley, Peter Willeit, Sune F Nielsen, Muriel Caslake, Stella Trompet, Linda M Polfus, Kari Kuulasmaa, Jukka Kontto, Markus Perola, Stefan Blankenberg, Giovanni Veronesi, Francesco Gianfagna, Satu Männistö, Akinori Kimura, Honghuang Lin, Dermot F Reilly, Mathias Gorski, Vladan Mijatovic, Patricia B Munroe, Georg B Ehret, Alex Thompson, Maria Uria-Nickelsen, Anders Malarstig, Abbas Dehghan, Thomas F Vogt, Taishi Sasaoka, Fumihiko Takeuchi, Norihiro Kato, Yoshiji Yamada, Frank Kee, Martina Müller-Nurasyid, Jean Ferrières, Dominique Arveiler, Philippe Amouyel, Veikko Salomaa, Eric Boerwinkle, Simon G Thompson, Ian Ford, J Wouter Jukema, Naveed Sattar, Chris J Packard, Abdulla Al Shafi Majumder, Dewan S Alam, Panos Deloukas, Heribert Schunkert, Nilesh J Samani, Sekar Kathiresan, Børge G Nordestgaard, Danish Saleheen, Joanna Mm Howson, Emanuele Di Angelantonio, Adam S Butterworth, John Danesh
AIMS: Darapladib, a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), has not reduced risk of cardiovascular disease outcomes in recent randomized trials. We aimed to test whether Lp-PLA2 enzyme activity is causally relevant to coronary heart disease. METHODS: In 72,657 patients with coronary heart disease and 110,218 controls in 23 epidemiological studies, we genotyped five functional variants: four rare loss-of-function mutations (c.109+2T > C (rs142974898), Arg82His (rs144983904), Val279Phe (rs76863441), Gln287Ter (rs140020965)) and one common modest-impact variant (Val379Ala (rs1051931)) in PLA2G7, the gene encoding Lp-PLA2...
December 11, 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27872105/multiethnic-exome-wide-association-study-of-subclinical-atherosclerosis
#15
Pradeep Natarajan, Joshua C Bis, Lawrence F Bielak, Amanda J Cox, Marcus Dörr, Mary F Feitosa, Nora Franceschini, Xiuqing Guo, Shih-Jen Hwang, Aaron Isaacs, Min A Jhun, Maryam Kavousi, Ruifang Li-Gao, Leo-Pekka Lyytikäinen, Riccardo E Marioni, Ulf Schminke, Nathan O Stitziel, Hayato Tada, Jessica van Setten, Albert V Smith, Dina Vojinovic, Lisa R Yanek, Jie Yao, Laura M Yerges-Armstrong, Najaf Amin, Usman Baber, Ingrid B Borecki, J Jeffrey Carr, Yii-Der Ida Chen, L Adrienne Cupples, Pim A de Jong, Harry de Koning, Bob D de Vos, Ayse Demirkan, Valentin Fuster, Oscar H Franco, Mark O Goodarzi, Tamara B Harris, Susan R Heckbert, Gerardo Heiss, Udo Hoffmann, Albert Hofman, Ivana Išgum, J Wouter Jukema, Mika Kähönen, Sharon L R Kardia, Brian G Kral, Lenore J Launer, Joe Massaro, Roxana Mehran, Braxton D Mitchell, Thomas H Mosley, Renée de Mutsert, Anne B Newman, Khanh-Dung Nguyen, Kari E North, Jeffrey R O'Connell, Matthijs Oudkerk, James S Pankow, Gina M Peloso, Wendy Post, Michael A Province, Laura M Raffield, Olli T Raitakari, Dermot F Reilly, Fernando Rivadeneira, Frits Rosendaal, Samantha Sartori, Kent D Taylor, Alexander Teumer, Stella Trompet, Stephen T Turner, Andre G Uitterlinden, Dhananjay Vaidya, Aad van der Lugt, Uwe Völker, Joanna M Wardlaw, Christina L Wassel, Stefan Weiss, Mary K Wojczynski, Diane M Becker, Lewis C Becker, Eric Boerwinkle, Donald W Bowden, Ian J Deary, Abbas Dehghan, Stephan B Felix, Vilmundur Gudnason, Terho Lehtimäki, Rasika Mathias, Dennis O Mook-Kanamori, Bruce M Psaty, Daniel J Rader, Jerome I Rotter, James G Wilson, Cornelia M van Duijn, Henry Völzke, Sekar Kathiresan, Patricia A Peyser, Christopher J O'Donnell
BACKGROUND: The burden of subclinical atherosclerosis in asymptomatic individuals is heritable and associated with elevated risk of developing clinical coronary heart disease. We sought to identify genetic variants in protein-coding regions associated with subclinical atherosclerosis and the risk of subsequent coronary heart disease. METHODS AND RESULTS: We studied a total of 25 109 European ancestry and African ancestry participants with coronary artery calcification (CAC) measured by cardiac computed tomography and 52 869 participants with common carotid intima-media thickness measured by ultrasonography within the CHARGE Consortium (Cohorts for Heart and Aging Research in Genomic Epidemiology)...
December 2016: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/27821413/lipoprotein-a-a-historical-appraisal
#16
REVIEW
Karam M Kostner, Gert M Kostner
Initially, lipoprotein (a) [Lp(a)] was believed to be a genetic variant of lipoprotein (Lp)-B. Because its lipid moiety is almost identical to LDL, Lp(a) has been deliberately considered to be highly atherogenic. Lp(a) was detected in 1963 by Kare Berg, and individuals who were positive for this factor were called Lpa(+) Lpa(+) individuals were found more frequently in patients with coronary heart disease than in controls. After the introduction of quantitative methods for monitoring of Lp(a), it became apparent that Lp(a), in fact, is present in all individuals, yet to a greatly variable extent...
January 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/27815926/hypertension-is-a-risk-factor-for-several-types-of-heart-disease-review-of-prospective-studies
#17
Yoshihiro Kokubo, Chisa Matsumoto
Many prospective cohort studies have demonstrated that hypertension is a strong risk factor for total mortality and cardiovascular disease (CVD). Heart disease includes coronary heart disease (CHD), heart failure, atrial fibrillation, valvular disease, sudden cardiac death (SCD), sick sinus syndrome (SSS), cardiomyopathy, and aortic aneurysms. Most of the epidemiologic prospective studies of heart disease focused on coronary/ischemic heart disease. Here we comprehensively reviewed the association between hypertension and the above-mentioned heart diseases...
November 5, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27812514/association-between-genetic-variations-affecting-mean-telomere-length-and-the-prevalence-of-hypertension-and-coronary-heart-disease-in-koreans
#18
Jean Kyung Paik, Ryungwoo Kang, Yoonsu Cho, Min-Jeong Shin
In this study, we investigated whether the single nucleotide polymorphisms (SNPs) associated with telomere length (TL) were associated with the incidence of hypertension (HTN)/coronary heart disease (CHD) and cardiovascular risk factors in the Korean population. Data from 5,705 (ages 39-70) participants in the Korean Genome Epidemiology Study (rural Ansung and urban Ansan cohorts) were studied. Twelve SNPs known to be associated with telomere biology were tested for an association with HTN/CHD. As results, no significant associations were found between the selected TL-related SNPs and prevalence of HTN and CHD...
October 2016: Clinical Nutrition Research
https://www.readbyqxmd.com/read/27773540/secondary-cv-prevention-in-south-america-in-a-community-setting-the-pure-study
#19
Alvaro Avezum, Gustavo B F Oliveira, Fernando Lanas, Patricio Lopez-Jaramillo, Rafael Diaz, J Jaime Miranda, Pamela Seron, Paul A Camacho-Lopez, Andres Orlandini, Antonio Bernabe-Ortiz, Antônio Cordeiro Mattos, Shofiqul Islam, Sumathy Rangarajan, Koon Teo, Salim Yusuf
BACKGROUND: Despite the availability of evidence-based therapies, there is no information on the use of medications for the secondary prevention of cardiovascular disease in urban and rural community settings in South America. OBJECTIVES: This study sought to assess the use, and its predictors, of effective secondary prevention therapies in individuals with a history of coronary heart disease (CHD) or stroke. METHODS: In the PURE (Prospective Urban Rural Epidemiological) study, we enrolled 24,713 individuals from South America ages 35 to 70 years from 97 rural and urban communities in Argentina, Brazil, Chile, and Colombia...
October 20, 2016: Global Heart
https://www.readbyqxmd.com/read/27758973/evolution-of-chagas-disease-in-brazil-epidemiological-perspective-and-challenges-for-the-future-a-critical-review
#20
Rafael Bello Corassa, Carmen Aceijas, Paula Aryane Brito Alves, Hemda Garelick
AIMS: This article aimed to provide a critical review of the evolution of Chagas' disease (ChD) in Brazil, its magnitude, historical development and management, and challenges for the future. METHODS: A literature search was performed using PubMed, SciELO and Google Scholar and throughout collected articles' references. Narrative analysis was structured around five main themes identified: vector transmission, control programme, transfusion, oral and congenital transmission...
October 10, 2016: Perspectives in Public Health
keyword
keyword
11277
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"