Edward L Barnes, Michael S Dunn, Jean Ashburn, Amy Barto, Richard Bloomfeld, Ashley Cairns, Kurren Mehta, Pooja Patel, Jennifer Dziwis, Scott Esckilsen, Reza Rahbar, Timothy S Sadiq, John S Hanson, Hans H Herfarth
INTRODUCTION: Our understanding of the epidemiology of inflammatory conditions of the pouch and effectiveness of treatment is largely based on selected populations. We created a state-level registry to evaluate the incidence of pouchitis and the effectiveness of treatments utilized in an initial episode of pouchitis. METHODS: In a state-level retrospective cohort of all patients undergoing proctocolectomy with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) between January 1, 2018 and December 31, 2020, we evaluated the incidence of pouchitis and compared the proportion of patients developing recurrent pouchitis and chronic antibiotic dependent pouchitis (CADP) according to initial antibiotic therapy...
December 26, 2023: Clinical and Translational Gastroenterology