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Andrew S Hwang, Steven J Atlas, Johan Hong, Jeffrey M Ashburner, Adrian H Zai, Richard W Grant, Clemens S Hong
BACKGROUND: A better understanding of the attributes of patients who require more effort to manage may improve risk adjustment approaches and lead to more efficient resource allocation, improved patient care and health outcomes, and reduced burnout in primary care clinicians. OBJECTIVE: To identify and characterize high-effort patients from the physician's perspective. DESIGN: Cohort study. PARTICIPANTS: Ninety-nine primary care physicians in an academic primary care network...
October 21, 2016: Journal of General Internal Medicine
Kim Ashburn, Brad Kerner, Dickens Ojamuge, Rebecka Lundgren
Violence against women and violence against children in Uganda are recognized as significant public health concerns. Exposure to violence at home as a child can increase the likelihood of perpetrating or experiencing violence later in life. These two forms of violence share similar risk factors and often, but not always, co-occur at the household level. Parenting programs have shown promise in reducing physical child punishment. Targeting men has also been proven effective in transforming attitudes related to gender roles and expectations and intimate partner violence (IPV) against women...
October 13, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
Catherine Bowen, Ann Ashburn, Mark Cole, Margaret Donovan-Hall, Malcolm Burnett, Judy Robison, Louis Mamode, Ruth Pickering, Dan Bader, Dorit Kunkel
BACKGROUND: Ill-fitting shoes have been implicated as a risk factor for falls but research to date has focused on people with arthritis, diabetes and the general older population; little is known about people with neurological conditions. This survey for people with stroke and Parkinson's explored people's choice of indoor and outdoor footwear, foot problems and fall history. METHODS: Following ethical approval, 1000 anonymous postal questionnaires were distributed to health professionals, leads of Parkinson's UK groups and stroke clubs in the wider Southampton area, UK...
2016: Journal of Foot and Ankle Research
Brownsyne Tucker Edmonds, Fatima McKenzie, MacKenzie B Austgen, Leslie Ashburn-Nardo, Marianne S Matthias, Adam T Hirsh
OBJECTIVE: Describe obstetrical providers' management of a hypothetical case on chronic pain in pregnancy and determine whether practices differ based on patient race. DESIGN AND SETTING: This was a self-administered survey at a clinical conference. SUBJECTS: Seventy-six obstetrician-gynecologists and one nurse practitioner were surveyed. METHODS: A case-vignette described a pregnant patient presenting with worsening chronic lower back pain, requesting an opioid refill and increased dosage...
August 14, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Sachin J Shah, Patrick Cronin, Clemens S Hong, Andrew S Hwang, Jeffrey M Ashburner, Benjamin I Bearnot, Calvin A Richardson, Blair W Fosburgh, Alexandra B Kimball
BACKGROUND: No-shows, or missed appointments, are a problem for many medical practices. They result in fragmented care and reduce access for all patients. OBJECTIVE: To determine whether telephone reminder calls targeted to patients at high risk of no-show can reduce no-show rates. DESIGN: Single-center randomized controlled trial. PARTICIPANTS: A total of 2247 primary care patients in a hospital-based primary care clinic at high risk of no-show (>15 % risk) for their appointment in 7 days...
August 8, 2016: Journal of General Internal Medicine
Sanja Percac-Lima, Jeffrey M Ashburner, Adrian H Zai, Yuchiao Chang, Sarah A Oo, Erica Guimaraes, Steven J Atlas
IMPORTANCE: Patient navigation (PN) to improve cancer screening in low-income and racial/ethnic minority populations usually focuses on navigating for single cancers in community health center settings. OBJECTIVE: We evaluated PN for breast, cervical, and colorectal cancer screening using a population-based information technology (IT) system within a primary care network. DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial conducted from April 2014 to December 2014 in 18 practices in an academic primary care network...
July 1, 2016: JAMA Internal Medicine
K Sun, I Zeimpekis, C Hu, N M J Ditshego, O Thomas, M R R de Planque, H M H Chong, H Morgan, P Ashburn
In this work, we investigate how the sensitivity of a nanowire or nanoribbon sensor is influenced by the subthreshold slope of the sensing transistor. Polysilicon nanoribbon sensors are fabricated with a wide range of subthreshold slopes and the sensitivity is characterized using pH measurements. It is shown that there is a strong relationship between the sensitivity and the device subthreshold slope. The sensitivity is characterized using the current sensitivity per pH, which is shown to increase from 1.2% ph(-1) to 33...
July 15, 2016: Nanotechnology
Jean H Ashburn, Matthew F Kalady
Radiotherapy not only plays a pivotal role in the cancer care pathways of many patients with pelvic malignancies, but can also lead to significant injury of normal tissue in the radiation field (pelvic radiation disease) that is sometimes as challenging to treat as the neoplasms themselves. Acute symptoms are usually self-limited and respond to medical therapy. Chronic symptoms often require operative intervention that is made hazardous by hostile surgical planes and unforgiving tissues. Management of these challenging patients is best guided by the utmost caution and humility...
June 2016: Clinics in Colon and Rectal Surgery
Michael A Ashburn
No abstract text is available yet for this article.
July 2016: Pharmacoepidemiology and Drug Safety
Perry G Fine, Michael A Ashburn
No abstract text is available yet for this article.
June 2016: Anesthesiology Clinics
Pam Enderby, Anand Pandyan, Audrey Bowen, David Hearnden, Ann Ashburn, Paul Conroy, Pip Logan, Carl Thompson, Jacqueline Winter
AIM: To explore the use, meaning and value of the term "rehabilitation potential". METHOD: The authors of this commentary met to discuss concerns relating to the pressure on health service staff created by reduced length of stay in acute settings of those who have suffered a stroke and the need to determine the potential of a patient for rehabilitation in order to inform discharge arrangements. Points raised at this meeting were shared with an email group who over a 12-month period contributed to this paper...
April 30, 2016: Disability and Rehabilitation
Patrick Freund, Karl Friston, Alan J Thompson, Klaas E Stephan, John Ashburner, Dominik R Bach, Zoltan Nagy, Gunther Helms, Bogdan Draganski, Siawoosh Mohammadi, Martin E Schwab, Armin Curt, Nikolaus Weiskopf
No abstract text is available yet for this article.
June 2016: Brain: a Journal of Neurology
Marco Crescentini, Michele Rossi, Peter Ashburn, Marta Lombardini, Enrico Sangiorgi, Hywel Morgan, Marco Tartagni
Silicon nanowires are label-free sensors that allow real-time measurements. They are economical and pave the road for point-of-care applications but require complex readout and skilled personnel. We propose a new model and technique for sensing nanowire sensors using alternating currents (AC) to capture both magnitude and phase information from the sensor. This approach combines the advantages of complex impedance spectroscopy with the noise reduction performances of lock-in techniques. Experimental results show how modifications of the sensors with different surface chemistries lead to the same direct-current (DC) response but can be discerned using the AC approach...
2016: Biosensors
Chunxiao Hu, Ioannis Zeimpekis, Kai Sun, Sally Anderson, Peter Ashburn, Hywel Morgan
We describe a low cost thin-film transistor (TFT) nanoribbon sensor for detection of the inflammatory biomarker C-reactive protein (CRP) in human serum via a miniature bead-based enzyme-linked immunosorbent assay (ELISA). The TFT nanoribbon sensor measures the reaction products from the ELISA via pH changes. The bead-based ELISA decouples the protein functionalization steps from the sensor surface, increasing the signal and simplifying the assay. The ability to directly sense proteins in human serum in this way overcomes the Debye length limitation associated with nanowire and nanoribbon biosensors...
May 3, 2016: Analytical Chemistry
Michael A Ashburn, Lee A Fleisher
No abstract text is available yet for this article.
March 2016: Healthcare
Emma Stack, Rachel King, Balazs Janko, Malcolm Burnett, Nicola Hammersley, Veena Agarwal, Sion Hannuna, Alison Burrows, Ann Ashburn
Self-report underpins our understanding of falls among people with Parkinson's (PwP) as they largely happen unwitnessed at home. In this qualitative study, we used an ethnographic approach to investigate which in-home sensors, in which locations, could gather useful data about fall risk. Over six weeks, we observed five independently mobile PwP at high risk of falling, at home. We made field notes about falls (prior events and concerns) and recorded movement with video, Kinect, and wearable sensors. The three women and two men (aged 71 to 79 years) having moderate or severe Parkinson's were dependent on others and highly sedentary...
2016: BioMed Research International
I Zeimpekis, K Sun, C Hu, N M J Ditshego, O Thomas, M R R de Planque, H M H Chong, H Morgan, P Ashburn
We demonstrate the advantages of dual-gate polysilicon nanoribbon biosensors with a comprehensive evaluation of different measurement schemes for pH and protein sensing. In particular, we compare the detection of voltage and current changes when top- and bottom-gate bias is applied. Measurements of pH show that a large voltage shift of 491 mV pH(-1) is obtained in the subthreshold region when the top-gate is kept at a fixed potential and the bottom-gate is varied (voltage sweep). This is an improvement of 16 times over the 30 mV pH(-1) measured using a top-gate sweep with the bottom-gate at a fixed potential...
April 22, 2016: Nanotechnology
Jill Ashburner, Jenny Ziviani, Sylvia Rodger, Elizabeth A Hinder, Linda Cartmill, Jessica White, Sandy Vickerstaff
INTRODUCTION: Research suggests that learning gained through training is infrequently implemented in the workplace. A short-term postcourse comentoring program was developed with the aim of facilitating workplace implementation of learning after a 3-day course for occupational therapists. The program was evaluated for usefulness, successes, challenges, recommended improvements, and associations with changes in self-rated knowledge and confidence. METHOD: Two months after the course, 42 participants completed an evaluation of the comentoring program with closed- and open-ended questions addressing usefulness, successes, challenges, pairing preferences, and recommendations...
2015: Journal of Continuing Education in the Health Professions
Xiangrui Li, Paul S Morgan, John Ashburner, Jolinda Smith, Christopher Rorden
BACKGROUND: Clinical imaging data are typically stored and transferred in the DICOM format, whereas the NIfTI format has been widely adopted by scientists in the neuroimaging community. Therefore, a vital initial step in processing the data is to convert images from the complicated DICOM format to the much simpler NIfTI format. While there are a number of tools that usually handle DICOM to NIfTI conversion seamlessly, some variations can disrupt this process. NEW METHOD: We provide some insight into the challenges faced with image conversion...
May 1, 2016: Journal of Neuroscience Methods
Sanja Percac-Lima, Jeffrey M Ashburner, Jo-Anne O Shepard, Inga T Lennes, Dorothy E Rimmelin, Steven J Atlas
PURPOSE: Diagnostic chest CT frequently results in abnormal findings that require follow-up. We assessed the timeliness of follow-up after CT abnormalities were identified in symptomatic smokers at high risk for developing lung cancer. METHODS: In an academic primary care network, we identified current smokers aged 55-79 years who received a diagnostic chest CT to evaluate symptoms during 2012. Medical chart abstraction identified radiologist recommendations and follow-up care...
May 2016: Journal of the American College of Radiology: JACR
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