Read by QxMD icon Read


Erman Aytac, David W Dietz, Jean Ashburn, Feza H Remzi
BACKGROUND: Patients with Crohn's disease have a higher failure rate after ileal pouch surgery compared with their counterparts with ulcerative colitis. OBJECTIVE: We hypothesized that risk of continent ileostomy failure can be stratified based on the timing of Crohn's disease diagnosis and aimed to assess long-term outcomes. DESIGN: This was a retrospective cohort study. SETTINGS: The investigation took place in a high-volume, specialized colorectal surgery department...
May 2017: Diseases of the Colon and Rectum
Michael A Ashburn, Rachel L Levine
Objective.:  The objective of this project was to develop core competencies for education on opioids and addiction to be used in all Pennsylvania medical schools. Methods.:  The Pennsylvania Physician General created a task force that was responsible for the creation of the core competencies. A literature review was completed, and a survey of graduating medical students was conducted. The task force then developed, reviewed, and approved the core competencies...
March 2, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Ferran Prados, John Ashburner, Claudia Blaiotta, Tom Brosch, Julio Carballido-Gamio, Manuel Jorge Cardoso, Benjamin N Conrad, Esha Datta, Gergely Dávid, Benjamin De Leener, Sara M Dupont, Patrick Freund, Claudia A M Gandini Wheeler-Kingshott, Francesco Grussu, Roland Henry, Bennett A Landman, Emil Ljungberg, Bailey Lyttle, Sebastien Ourselin, Nico Papinutto, Salvatore Saporito, Regina Schlaeger, Seth A Smith, Paul Summers, Roger Tam, Marios C Yiannakas, Alyssa Zhu, Julien Cohen-Adad
An important image processing step in spinal cord magnetic resonance imaging is the ability to reliably and accurately segment grey and white matter for tissue specific analysis. There are several semi- or fully-automated segmentation methods for cervical cord cross-sectional area measurement with an excellent performance close or equal to the manual segmentation. However, grey matter segmentation is still challenging due to small cross-sectional size and shape, and active research is being conducted by several groups around the world in this field...
March 7, 2017: NeuroImage
Volkan Ozben, Luca Stocchi, Jean Ashburn, Xiaobo Liu, Emre Gorgun
AIM: The aim of this study was to investigate the impact of restrictive versus liberal transfusion strategy on anastomotic leakage and infectious complications after rectal cancer surgery. METHODS: Patients undergoing restorative proctectomy for rectal cancer between 01/2008 and 12/2013 were divided into four groups according to the perioperative lowest haemoglobin (Hgb) level and transfusion status: Group 1 with Hgb level ≥10 g/dL, Group 2 ≥7 and <10 g/dL, who did not receive transfusion, and Group 3 with Hgb level ≥7 and <10 g/dL and Group 4 <7 g/dL, both of which received a transfusion...
February 26, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
N Hollingshead, L Ashburn-Nardo, J Stewart, G Maupomé, A Hirsh
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
Loraine J Bacchus, Manuela Colombini, Manuel Contreras Urbina, Emma Howarth, Frances Gardner, Jeannie Annan, Kim Ashburn, Bernadette Madrid, Ruti Levtov, Charlotte Watts
Intimate partner violence (IPV) and child maltreatment (CM) by a parent or caregiver are prevalent and overlapping issues with damaging consequences for those affected. This scoping review aimed to identify opportunities for greater coordination between IPV and CM programmes in low- and middle-income countries (LMIC). Nine bibliographic databases were searched and grey literature was identified through the scoping review team. Eligible studies were published in English; described primary prevention programmes in LMIC that addressed IPV and CM, or addressed one form of violence, but reported outcomes for the other; reported IPV and CM outcomes; and evaluated with any study design...
February 2, 2017: Psychology, Health & Medicine
Gabriel Ziegler, Gerard R Ridgway, Sarah-Jayne Blakemore, John Ashburner, Will Penny
Here we introduce a multivariate framework for characterising longitudinal changes in structural MRI using dynamical systems. The general approach enables modelling changes of states in multiple imaging biomarkers typically observed during brain development, plasticity, ageing and degeneration, e.g. regional gray matter volume of multiple regions of interest (ROIs). Structural brain states follow intrinsic dynamics according to a linear system with additional inputs accounting for potential driving forces of brain development...
February 15, 2017: NeuroImage
Jessica Philpott, Jean Ashburn, Bo Shen
No abstract text is available yet for this article.
January 2017: Inflammatory Bowel Diseases
Catherine E Callinan, Mark D Neuman, Kim E Lacy, Claudia Gabison, Michael A Ashburn
This study reports the results of a researcher-administered survey with 115 patients receiving chronic opioid therapy (>90 days) to obtain information regarding how chronic opioid therapy was started. Chronic opioids were started after surgery (27.0%, 95% confidence interval [CI], 18.5-35.5) or for the treatment of acute injury-related pain (27.0%, 95% CI, 18.5-35.5). Many who initiated opioid therapy after surgery reported postoperative complications (61.3%, 95% CI, 50.8-71.8) and many with injury-related pain reported follow-up corrective surgery (58...
December 3, 2016: Journal of Pain: Official Journal of the American Pain Society
Jeffrey M Ashburner, Alan S Go, Yuchiao Chang, Margaret C Fang, Lisa Fredman, Katie M Applebaum, Daniel E Singer
OBJECTIVES: To provide greater understanding of the "real world" effect of anticoagulation on stroke risk over several years. DESIGN: Cohort study. SETTING: Anticoagulation and Risk Factors in Atrial Fibrillation Study community-based cohort. PARTICIPANTS: Adults with nonvalvular atrial fibrillation (AF) between 1996 and 2003 (13,559). MEASUREMENTS: All events were clinician adjudicated. Extended Cox regression with longitudinal warfarin exposure was used to estimate cause-specific hazard ratios (HRs) for thromboembolism and the competing risk event (all cause death)...
January 2017: Journal of the American Geriatrics Society
Gemma L Holliday, Rebecca Davidson, Eyal Akiva, Patricia C Babbitt
The Gene Ontology (GO) (Ashburner et al., Nat Genet 25(1):25-29, 2000) is a powerful tool in the informatics arsenal of methods for evaluating annotations in a protein dataset. From identifying the nearest well annotated homologue of a protein of interest to predicting where misannotation has occurred to knowing how confident you can be in the annotations assigned to those proteins is critical. In this chapter we explore what makes an enzyme unique and how we can use GO to infer aspects of protein function based on sequence similarity...
2017: Methods in Molecular Biology
Andrew S Hwang, Steven J Atlas, Johan Hong, Jeffrey M Ashburner, Adrian H Zai, Richard W Grant, Clemens S Hong
BACKGROUND: A better understanding of the attributes of patients who require more effort to manage may improve risk adjustment approaches and lead to more efficient resource allocation, improved patient care and health outcomes, and reduced burnout in primary care clinicians. OBJECTIVE: To identify and characterize high-effort patients from the physician's perspective. DESIGN: Cohort study. PARTICIPANTS: Ninety-nine primary care physicians in an academic primary care network...
March 2017: Journal of General Internal Medicine
Kim Ashburn, Brad Kerner, Dickens Ojamuge, Rebecka Lundgren
Violence against women and violence against children in Uganda are recognized as significant public health concerns. Exposure to violence at home as a child can increase the likelihood of perpetrating or experiencing violence later in life. These two forms of violence share similar risk factors and often, but not always, co-occur at the household level. Parenting programs have shown promise in reducing physical child punishment. Targeting men has also been proven effective in transforming attitudes related to gender roles and expectations and intimate partner violence (IPV) against women...
October 13, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
Catherine Bowen, Ann Ashburn, Mark Cole, Margaret Donovan-Hall, Malcolm Burnett, Judy Robison, Louis Mamode, Ruth Pickering, Dan Bader, Dorit Kunkel
BACKGROUND: Ill-fitting shoes have been implicated as a risk factor for falls but research to date has focused on people with arthritis, diabetes and the general older population; little is known about people with neurological conditions. This survey for people with stroke and Parkinson's explored people's choice of indoor and outdoor footwear, foot problems and fall history. METHODS: Following ethical approval, 1000 anonymous postal questionnaires were distributed to health professionals, leads of Parkinson's UK groups and stroke clubs in the wider Southampton area, UK...
2016: Journal of Foot and Ankle Research
Brownsyne Tucker Edmonds, Fatima McKenzie, MacKenzie B Austgen, Leslie Ashburn-Nardo, Marianne S Matthias, Adam T Hirsh
OBJECTIVE: Describe obstetrical providers' management of a hypothetical case on chronic pain in pregnancy and determine whether practices differ based on patient race. DESIGN AND SETTING: This was a self-administered survey at a clinical conference. SUBJECTS: Seventy-six obstetrician-gynecologists and one nurse practitioner were surveyed. METHODS: A case-vignette described a pregnant patient presenting with worsening chronic lower back pain, requesting an opioid refill and increased dosage...
August 14, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Sachin J Shah, Patrick Cronin, Clemens S Hong, Andrew S Hwang, Jeffrey M Ashburner, Benjamin I Bearnot, Calvin A Richardson, Blair W Fosburgh, Alexandra B Kimball
BACKGROUND: No-shows, or missed appointments, are a problem for many medical practices. They result in fragmented care and reduce access for all patients. OBJECTIVE: To determine whether telephone reminder calls targeted to patients at high risk of no-show can reduce no-show rates. DESIGN: Single-center randomized controlled trial. PARTICIPANTS: A total of 2247 primary care patients in a hospital-based primary care clinic at high risk of no-show (>15 % risk) for their appointment in 7 days...
December 2016: Journal of General Internal Medicine
Sanja Percac-Lima, Jeffrey M Ashburner, Adrian H Zai, Yuchiao Chang, Sarah A Oo, Erica Guimaraes, Steven J Atlas
IMPORTANCE: Patient navigation (PN) to improve cancer screening in low-income and racial/ethnic minority populations usually focuses on navigating for single cancers in community health center settings. OBJECTIVE: We evaluated PN for breast, cervical, and colorectal cancer screening using a population-based information technology (IT) system within a primary care network. DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial conducted from April 2014 to December 2014 in 18 practices in an academic primary care network...
July 1, 2016: JAMA Internal Medicine
K Sun, I Zeimpekis, C Hu, N M J Ditshego, O Thomas, M R R de Planque, H M H Chong, H Morgan, P Ashburn
In this work, we investigate how the sensitivity of a nanowire or nanoribbon sensor is influenced by the subthreshold slope of the sensing transistor. Polysilicon nanoribbon sensors are fabricated with a wide range of subthreshold slopes and the sensitivity is characterized using pH measurements. It is shown that there is a strong relationship between the sensitivity and the device subthreshold slope. The sensitivity is characterized using the current sensitivity per pH, which is shown to increase from 1.2% ph(-1) to 33...
July 15, 2016: Nanotechnology
Jean H Ashburn, Matthew F Kalady
Radiotherapy not only plays a pivotal role in the cancer care pathways of many patients with pelvic malignancies, but can also lead to significant injury of normal tissue in the radiation field (pelvic radiation disease) that is sometimes as challenging to treat as the neoplasms themselves. Acute symptoms are usually self-limited and respond to medical therapy. Chronic symptoms often require operative intervention that is made hazardous by hostile surgical planes and unforgiving tissues. Management of these challenging patients is best guided by the utmost caution and humility...
June 2016: Clinics in Colon and Rectal Surgery
Michael A Ashburn
No abstract text is available yet for this article.
July 2016: Pharmacoepidemiology and Drug Safety
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"