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https://www.readbyqxmd.com/read/29313223/impact-of-a-population-health-management-intervention-on-disparities-in-cardiovascular-disease-control
#1
Aisha James, Seth A Berkowitz, Jeffrey M Ashburner, Yuchiao Chang, Daniel M Horn, Sandra M O'Keefe, Steven J Atlas
BACKGROUND: Healthcare systems use population health management programs to improve the quality of cardiovascular disease care. Adding a dedicated population health coordinator (PHC) who identifies and reaches out to patients not meeting cardiovascular care goals to these programs may help reduce disparities in cardiovascular care. OBJECTIVE: To determine whether a program that used PHCs decreased racial/ethnic disparities in LDL cholesterol and blood pressure (BP) control...
January 8, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29285681/outcomes-of-ileal-pouch-anal-anastomosis-without-primary-diverting-loop-ileostomy-if-postoperative-sepsis-develops
#2
O A Lavryk, T L Hull, L C Duraes, L Stocchi, J H Ashburn, D Liska, E Gorgun, H Kessler
BACKGROUND: The aim of the present study was to assess the short-term and long-term consequences of diverting loop ileostomy (DLI) omission in ileal pouch-anal anastomosis (IPAA) surgery complicated by postoperative pelvic sepsis. METHODS: This was a retrospective review of a prospectively maintained database. Of 4031 patients who underwent IPAA in 1983-2014, 357 developed IPAA-related pelvic sepsis with or without anastomotic dehiscence. Patients with Crohn's disease or cancer were excluded...
December 28, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29261239/chronic-disease-outcomes-from-primary-care-population-health-program-implementation
#3
Jeffrey M Ashburner, Daniel M Horn, Sandra M O'Keefe, Adrian H Zai, Yuchiao Chang, Neil W Wagle, Steven J Atlas
OBJECTIVES: We implemented a health information technology-enabled population health management program for chronic disease management in academic hospital-affiliated primary care practices, then compared quality-of-care outcome measures among practices assigned a central population health coordinator (PHC) and those not assigned a PHC. STUDY DESIGN: Quasi-experimental. METHODS: Central PHCs were nonrandomly assigned to 8 of 18 practices. They met with physicians, managed lists of patients not at goal in chronic disease registries, and performed administrative tasks...
December 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29238829/the-role-of-gabapentin-in-multimodal-postoperative-pain-management
#4
Michael A Ashburn, Lee A Fleisher
No abstract text is available yet for this article.
December 13, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29165824/measurement-of-social-norms-affecting-modern-contraceptive-use-a-literature-review
#5
Elizabeth Costenbader, Rachel Lenzi, Rebecca B Hershow, Kim Ashburn, Donna R McCarraher
As a critical building block to developing social norms interventions to support healthy family planning and other reproductive health behaviors, we conducted a literature review to identify and evaluate social norm measures related to modern contraceptive use. Of 174 articles reviewed in full, only 17 studies met our criteria for inclusion. Across these articles, no single measure of norms was used in more than one study; failure to specify the boundaries of who was engaging in and influencing the behaviors of interest contributed to the variation...
November 22, 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/29154627/distinct-kinematic-markers-of-demonstration-and-joint-action-coordination-evidence-from-virtual-xylophone-playing
#6
Luke McEllin, G√ľnther Knoblich, Natalie Sebanz
When performing joint actions, people modulate instrumental actions to provide additional information for a coactor (Pezzulo, Donnarumma, & Dindo, 2013). Similarly, demonstrators adjust instrumental actions to make them more informative for novice learners (Brand, Baldwin, & Ashburn, 2002). It is unknown whether the kinematic modulations performed to facilitate prediction in joint action coordination and the modulations performed to transmit information about the structure of novel actions are unique, or whether a general type of modulation can take on multiple functions...
November 20, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29135694/impact-of-prostate-cancer-and-its-treatment-on-the-outcomes-of-ileal-pouch-anal-anastomosis
#7
Lei Lian, Jean Ashburn, Erick M Remer, Feza H Remzi, Manoj Monga, Bo Shen
BACKGROUND: There are scant published data in the impact of prostate cancer and its treatment on functional outcomes and quality of life (QOL) in patients with ileal pouch-anal anastomosis (IPAA). The aim of the study was to evaluate the influence of prostate cancer and its treatment on functional outcomes and QOL in patients with IPAA. METHODS: Patients with IPAA with prostate cancer were compared to age and pouch duration-matched controls without prostate cancer in a 1:2 ratio...
December 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29100938/generative-diffeomorphic-modelling-of-large-mri-data-sets-for-probabilistic-template-construction
#8
Claudia Blaiotta, Patrick Freund, M Jorge Cardoso, John Ashburner
In this paper we present a hierarchical generative model of medical image data, which can capture simultaneously the variability of both signal intensity and anatomical shapes across large populations. Such a model has a direct application for learning average-shaped probabilistic tissue templates in a fully automated manner. While in principle the generality of the proposed Bayesian approach makes it suitable to address a wide range of medical image computing problems, our work focuses primarily on neuroimaging applications...
October 31, 2017: NeuroImage
https://www.readbyqxmd.com/read/29030455/optimal-deep-brain-stimulation-site-and-target-connectivity-for-chronic-cluster-headache
#9
Harith Akram, Sarah Miller, Susie Lagrata, Marwan Hariz, John Ashburner, Tim Behrens, Manjit Matharu, Ludvic Zrinzo
OBJECTIVE: To investigate the mechanism of action of deep brain stimulation for refractory chronic cluster headache and the optimal target within the ventral tegmental area. METHODS: Seven patients with refractory chronic cluster headache underwent high spatial and angular resolution diffusion MRI preoperatively. MRI-guided and MRI-verified electrode implantation was performed unilaterally in 5 patients and bilaterally in 2. Volumes of tissue activation were generated around active lead contacts with a finite-element model...
October 13, 2017: Neurology
https://www.readbyqxmd.com/read/28967376/a-very-early-rehabilitation-trial-after-stroke-avert-a-phase-iii-multicentre-randomised-controlled-trial
#10
Peter Langhorne, Olivia Wu, Helen Rodgers, Ann Ashburn, Julie Bernhardt
BACKGROUND: Mobilising patients early after stroke [early mobilisation (EM)] is thought to contribute to the beneficial effects of stroke unit care but it is poorly defined and lacks direct evidence of benefit. OBJECTIVES: We assessed the effectiveness of frequent higher dose very early mobilisation (VEM) after stroke. DESIGN: We conducted a parallel-group, single-blind, prospective randomised controlled trial with blinded end-point assessment using a web-based computer-generated stratified randomisation...
September 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28933613/a-randomized-controlled-feasibility-trial-exploring-partnered-ballroom-dancing-for-people-with-parkinson-s-disease
#11
D Kunkel, C Fitton, L Roberts, R M Pickering, H C Roberts, R Wiles, S Hulbert, J Robison, A Ashburn
OBJECTIVE: To determine the feasibility of a Dance Centre delivering a programme of mixed dances to people with Parkinson's and identify suitable outcomes for a future definitive trial. DESIGN: A two-group randomized controlled feasibility trial. METHODS: People with Parkinson's were randomized to a control or experimental group (ratio 15:35), alongside usual care. In addition, participants in the experimental group danced with a partner for one hour, twice-a-week for 10 weeks; professional dance teachers led the classes and field-notes were kept...
October 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28876021/first-principles-study-of-the-mn-doping-effect-on-the-physical-and-chemical-properties-of-mullite-family-al2sio5
#12
Qingbo Wang, Chaoping Liang, Yongping Zheng, Nickolas Ashburn, Young Jun Oh, Fantai Kong, Chenxi Zhang, Yifan Nie, Jian Sun, Kaihua He, Yu Ye, Rong Chen, Bin Shan, Kyeongjae Cho
Transition metal (TM) modification is a common strategy for converting an earth-abundant mineral into a cost-effective catalyst for industrial applications. Among a variety of minerals, Al2SiO5, which has three phases, andalusite, sillimanite and kyanite, is emerging as a promising candidate for new catalyst development. In this paper, we use Mn to demonstrate the rationale of 3d TM doping at the Al sites in each of these three phases through first-principles calculations and the cluster expansion method. The results of cluster expansion show that Mn has a strong site preference for the six-coordinated Al octahedral chains in the andalusite and sillimanite phases, while distributing randomly in the kyanite phase...
September 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28862645/a-sub-30-mph-resolution-thin-film-transistor-based-nanoribbon-biosensing-platform
#13
Ioannis Zeimpekis, Konstantinos I Papadimitriou, Kai Sun, Chunxiao Hu, Peter Ashburn, Hywel Morgan, Themistoklis Prodromakis
We present a complete biosensing system that comprises a Thin Film Transistor (TFT)-based nanoribbon biosensor and a low noise, high-performance bioinstrumentation platform, capable of detecting sub-30 mpH unit changes, validated by an enzymatic biochemical reaction. The nanoribbon biosensor was fabricated top-down with an ultra-thin (15 nm) polysilicon semiconducting channel that offers excellent sensitivity to surface potential changes. The sensor is coupled to an integrated circuit (IC), which combines dual switched-capacitor integrators with high precision analog-to-digital converters (ADCs)...
September 1, 2017: Sensors
https://www.readbyqxmd.com/read/28852524/fecal-microbiota-transplantation-for-clostridium-difficile-infection-in-patients-with-ileal-pouches
#14
Nan Lan, Jean Ashburn, Bo Shen
Background:Clostridium difficile infection (CDI) in patients with ileal pouch-anal anastomosis (IPAA) has been increasingly recognized. The aim of this study was to evaluate the outcome of fecal microbiota transplantation (FMT) in patients with pouch and CDI. Methods: All consecutive patients that underwent FMT for CDI from 2012 to 2016 were extracted from our IRB-approved, prospectively maintained Registry of Pouch Disorders. The primary outcome was negative stool tests for Clostridium difficile after FMT and the secondary outcomes were symptomatic and endoscopic responses...
August 2017: Gastroenterology Report
https://www.readbyqxmd.com/read/28795112/real-time-fmri-data-for-testing-opennft-functionality
#15
Yury Koush, John Ashburner, Evgeny Prilepin, Ronald Sladky, Peter Zeidman, Sergei Bibikov, Frank Scharnowski, Artem Nikonorov, Dimitri Van De Ville
Here, we briefly describe the real-time fMRI data that is provided for testing the functionality of the open-source Python/Matlab framework for neurofeedback, termed Open NeuroFeedback Training (OpenNFT, Koush et al. [1]). The data set contains real-time fMRI runs from three anonymized participants (i.e., one neurofeedback run per participant), their structural scans and pre-selected ROIs/masks/weights. The data allows for simulating the neurofeedback experiment without an MR scanner, exploring the software functionality, and measuring data processing times on the local hardware...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28711737/subthalamic-deep-brain-stimulation-sweet-spots-and-hyperdirect-cortical-connectivity-in-parkinson-s-disease
#16
Harith Akram, Stamatios N Sotiropoulos, Saad Jbabdi, Dejan Georgiev, Philipp Mahlknecht, Jonathan Hyam, Thomas Foltynie, Patricia Limousin, Enrico De Vita, Marjan Jahanshahi, Marwan Hariz, John Ashburner, Tim Behrens, Ludvic Zrinzo
OBJECTIVES: Firstly, to identify subthalamic region stimulation clusters that predict maximum improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and secondly, to map-out the cortical fingerprint, mediated by the hyperdirect pathways which predict maximum efficacy. METHODS: High angular resolution diffusion imaging in twenty patients with advanced Parkinson's disease was acquired prior to bilateral subthalamic nucleus deep brain stimulation...
July 12, 2017: NeuroImage
https://www.readbyqxmd.com/read/28693744/changes-in-use-of-anticoagulation-in-patients-with-atrial-fibrillation-within-a-primary-care-network-associated-with-the-introduction-of-direct-oral-anticoagulants
#17
MULTICENTER STUDY
Jeffrey M Ashburner, Daniel E Singer, Steven A Lubitz, Leila H Borowsky, Steven J Atlas
Atrial fibrillation (AF) and the decision to anticoagulate is a common problem faced by primary care physicians. Oral anticoagulation (OAC) is underused, despite its clear benefits with regard to stroke prevention. We examined OAC usage between 2010 and 2015, following the introduction of direct oral anticoagulants (DOACs) and specifically assessed whether more patients were anticoagulated over time. The study cohort included adult patients aged 18 and older with AF cared for in an 18-practice primary care network between 2010 and 2015...
September 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28681450/-the-optimization-of-superficial-planning-target-volumes-ptvs-with-helical-tomotherapy-jacmp-15-6-2014
#18
M Ashburner, G S Tudor
No abstract text is available yet for this article.
July 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28649492/relationship-between-brainstem-neurodegeneration-and-clinical-impairment-in-traumatic-spinal-cord-injury
#19
Patrick Grabher, Claudia Blaiotta, John Ashburner, Patrick Freund
BACKGROUND: Brainstem networks are pivotal in sensory and motor function and in recovery following experimental spinal cord injury (SCI). OBJECTIVE: To quantify neurodegeneration and its relation to clinical impairment in major brainstem pathways and nuclei in traumatic SCI. METHODS: Quantitative MRI data of 30 chronic traumatic SCI patients (15 with tetraplegia and 15 with paraplegia) and 23 controls were acquired. Patients underwent a full neurological examination...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28645842/opennft-an-open-source-python-matlab-framework-for-real-time-fmri-neurofeedback-training-based-on-activity-connectivity-and-multivariate-pattern-analysis
#20
Yury Koush, John Ashburner, Evgeny Prilepin, Ronald Sladky, Peter Zeidman, Sergei Bibikov, Frank Scharnowski, Artem Nikonorov, Dimitri Van De Ville
Neurofeedback based on real-time functional magnetic resonance imaging (rt-fMRI) is a novel and rapidly developing research field. It allows for training of voluntary control over localized brain activity and connectivity and has demonstrated promising clinical applications. Because of the rapid technical developments of MRI techniques and the availability of high-performance computing, new methodological advances in rt-fMRI neurofeedback become possible. Here we outline the core components of a novel open-source neurofeedback framework, termed Open NeuroFeedback Training (OpenNFT), which efficiently integrates these new developments...
June 21, 2017: NeuroImage
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