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https://www.readbyqxmd.com/read/28338786/recombination-mediated-host-adaptation-by-avian-staphylococcus-aureus
#1
Susan Murray, Ben Pascoe, Guillaume Méric, Leonardos Mageiros, Koji Yahara, Matthew D Hitchings, Yasmin Friedmann, Thomas S Wilkinson, Fraser J Gormley, Dietrich Mack, James E Bray, Sarah Lamble, Rory Bowden, Keith A Jolley, Martin C J Maiden, Sarah Wendlandt, Stefan Schwarz, Jukka Corander, J Ross Fitzgerald, Samuel K Sheppard
Staphylococcus aureus are globally disseminated among farmed chickens causing skeletal muscle infections, dermatitis and septicaemia. The emergence of poultry-associated lineages has involved zoonotic transmission from humans to chickens but questions remain about the specific adaptations that promote proliferation of chicken pathogens. We characterised genetic variation in a population of genome-sequenced S. aureus isolates of poultry and human origin. Genealogical analysis identified a dominant poultry-associated sequence cluster within the CC5 clonal complex...
February 28, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28327847/-evolution-and-regional-differences-in-mortality-due-to-suicide-in-peru-2004-2013
#2
Akram Hernández-Vásquez, Diego Azañedo, Juan Rubilar-González, Bertha Huarez, Leandro Grendas
The aim of this study was to estimate and analyze the evolution of mortality rates due to suicide in Peru between 2004 and 2013. National death records from the Peruvian Ministry of Health were analyzed, calculating the regional mortality rates due to suicide standardized by age. Similarly, rates grouped in 5-year periods were geospatially projected. There were 3,162 cases of suicide (67.2% men); the age range with the highest incidence was 20 to 29 years (28.7%) and 49.2% were due to poisoning. Suicide rates increased from 0...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28327171/the-association-of-time-and-medications-with-changes-in-bone-mineral-density-in-the-2%C3%A2-years-after-critical-illness
#3
Neil R Orford, Michael Bailey, Rinaldo Bellomo, Julie A Pasco, Claire Cattigan, Tania Elderkin, Sharon L Brennan-Olsen, David J Cooper, Mark A Kotowicz
BACKGROUND: Critical illness is associated with increased risk of fragility fracture and loss of bone mineral density (BMD), although the impact of medication exposures (bone anti-fracture therapy or glucocorticoids) and time remain unexplored. The objective of this study was to describe the association of time after ICU admission, and post-ICU administration of bone anti-fracture therapy or glucocorticoids after critical illness, with change in BMD. METHODS: In this prospective observational study, conducted in a tertiary hospital ICU, we studied adult patients requiring mechanical ventilation for at least 24 hours and measured BMD annually for 2 years after ICU discharge...
March 21, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28325967/some-taxonomic-notes-on-the-genus-oberea-dejean-1835-from-asia-coleoptera-cerambycidae-lamiinae
#4
Zhu Li, Giulio Cuccodoro, Li Chen
In the current work, the following taxonomic changes of genus Oberea Dejean, 1835 are proposed: Oberea flavescens Breuning, 1947, rest. stat.; Oberea toi Gressitt, 1939, rest. stat.; Oberea sylvia Pascoe, 1858, rest. stat.; Oberea taiwana Matsushita, 1933 = Oberea taihokuensis Breuning, 1962, syn. n.; Oberea sumbana Breuning, 1961 = Oberea antennata Franz, 1972, syn. n.; Oberea brevithorax Gressitt, 1939 is newly recorded from Vietnam.
2017: ZooKeys
https://www.readbyqxmd.com/read/28316636/the-siesta-trial-a-randomized-study-investigating-the-efficacy-safety-and-tolerability-of-acupressure-versus-sham-therapy-for-improving-sleep-quality-in-patients-with-end-stage-kidney-disease-on-hemodialysis
#5
Kunyu Shen, Yeoungjee Cho, Elaine M Pascoe, Carmel M Hawley, Veronica Oliver, Kathryn M Hughes, Richard Baer, Jeremy Frazier, Elizabeth Jarvis, Ken-Soon Tan, Xusheng Liu, Glenda Gobe, David W Johnson
Objectives. To compare the effectiveness of real acupressure versus sham acupressure therapy in improving sleep quality in patients receiving hemodialysis (HD) or hemodiafiltration (HDF). Methods. A multicenter, single-blind, randomized controlled trial was conducted in two Australian dialysis units located in Princess Alexandra Hospital and Logan Hospital, respectively. Forty-two subjects with self-reported poor sleep quality were randomly assigned to real (n = 21) or sham (n = 21) acupressure therapy delivered thrice weekly for four consecutive weeks during routine dialysis sessions...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28289256/global-change-parasite-transmission-and-disease-control-lessons-from-ecology
#6
REVIEW
Joanne Cable, Iain Barber, Brian Boag, Amy R Ellison, Eric R Morgan, Kris Murray, Emily L Pascoe, Steven M Sait, Anthony J Wilson, Mark Booth
Parasitic infections are ubiquitous in wildlife, livestock and human populations, and healthy ecosystems are often parasite rich. Yet, their negative impacts can be extreme. Understanding how both anticipated and cryptic changes in a system might affect parasite transmission at an individual, local and global level is critical for sustainable control in humans and livestock. Here we highlight and synthesize evidence regarding potential effects of 'system changes' (both climatic and anthropogenic) on parasite transmission from wild host-parasite systems...
May 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28279677/ready-willing-and-able-a-survey-of-clinicians-perceptions-about-domestic-violence-screening-in-a-regional-hospital-emergency-department
#7
Elham Saberi, Nicole Eather, Sharene Pascoe, Mary-Louise McFadzean, Frances Doran, Marie Hutchinson
BACKGROUND: Domestic violence (DV) has significant health impacts for victims and their families. Despite evidence that routine screening increases the identification of DV and opportunities for support; routine screening is uncommon in Australian emergency departments (EDs). This study explored ED clinicians' level of support for DV screening; current screening practices; and perceived barriers and readiness to screen prior to a pilot intervention. METHODS: Census survey of 76 ED clinicians...
March 6, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28278518/the-actin-regulator-zyxin-reinforces-airway-smooth-muscle-and-accumulates-in-airways-of-fatal-asthmatics
#8
Sonia R Rosner, Christopher D Pascoe, Elizabeth Blankman, Christopher C Jensen, Ramaswamy Krishnan, Alan L James, John G Elliot, Francis H Green, Jeffrey C Liu, Chun Y Seow, Jin-Ah Park, Mary C Beckerle, Peter D Paré, Jeffrey J Fredberg, Mark A Smith
Bronchospasm induced in non-asthmatic human subjects can be easily reversed by a deep inspiration (DI) whereas bronchospasm that occurs spontaneously in asthmatic subjects cannot. This physiological effect of a DI has been attributed to the manner in which a DI causes airway smooth muscle (ASM) cells to stretch, but underlying molecular mechanisms-and their failure in asthma-remain obscure. Using cells and tissues from wild type and zyxin-/- mice we report responses to a transient stretch of physiologic magnitude and duration...
2017: PloS One
https://www.readbyqxmd.com/read/28264364/notes-on-the-genera-i-antinia-i-pascoe-1871-and-i-dermatodina-i-faust-1895-with-description-of-i-d-boroveci-i-sp-nov-from-thailand-coleoptera-curculionidae-entiminae
#9
Jarosław Kania, Agata Piwnik
The generic status of Dermatodina Faust, 1895 is restored and characters distinguishing this genus from Antinia Pascoe, 1871 are discussed. A new species, Dermatodina boroveci sp. nov., is described from Thailand. A checklist of species placed within the two genera is provided.
February 16, 2017: Zootaxa
https://www.readbyqxmd.com/read/28250962/the-herts-and-minds-study-evaluating-the-effectiveness-of-mentalization-based-treatment-mbt-as-an-intervention-for-children-in-foster-care-with-emotional-and-or-behavioural-problems-a-phase-ii-feasibility-randomised-controlled-trial
#10
Nick Midgley, Sarah Jane Besser, Helen Dye, Pasco Fearon, Tim Gale, Kiri Jefferies-Sewell, Karen Irvine, Joyce Robinson, Solange Wyatt, David Wellsted, Sally Wood
BACKGROUND: A significant proportion of children in the social care system in England present with mental health problems, with the majority experiencing some form of emotional and behavioural difficulties. The most effective treatments for these children are currently unknown, partly due to a lack of robust, controlled studies. Researchers have identified a number of obstacles to conducting well-designed research with this population, making the need to test the feasibility of a randomised controlled trial especially important...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28246138/association-between-bipolar-spectrum-disorder-and-bone-health-a-meta-analysis-and-systematic-review-protocol
#11
Vinoomika Chandrasekaran, Sharon L Brennan-Olsen, Amanda L Stuart, Julie A Pasco, Michael Berk, Jason M Hodge, Lana J Williams
INTRODUCTION: Bipolar spectrum disorder is a chronic, episodic illness, associated with significant personal, social and economic burden. It is estimated to affect ∼2.4% of the population worldwide and is commonly associated with psychological and/or physiological comorbidities. Osteoporosis is one such comorbidity, a disease of bone that is asymptomatic until a fracture occurs. This systematic review attempts to capture, collate, assess and discuss the literature investigating the association between bipolar spectrum disorder and bone health...
February 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28245854/development-of-the-systemic-lupus-erythematosus-steroid-questionnaire-ssq-a-novel-patient-reported-outcome-tool-to-assess-the-impact-of-oral-steroid-treatment
#12
Susan D Mathias, Pamela Berry, Jane De Vries, Anca Askanase, Katie Pascoe, Hilary H Colwell, David J Chang
BACKGROUND: Oral glucocorticoids (steroids) are the mainstay of treatment for systemic lupus erythematosus (SLE), but their use is often associated with short- and long-term side effects. Following a literature review and discussions with patients with SLE, clinicians, and payers, a need was identified for a comprehensive SLE-specific tool that can be used to evaluate the side effects and benefits of steroids over time from a patient perspective. The objective of this study was to develop a patient-reported outcome (PRO) measure to assess general impact (baseline burden), benefits, side effects, and impacts associated with the use of oral steroids in patients with SLE...
February 28, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28245280/serotonin-transporter-gene-slc6a4-polymorphism-and-susceptibility-to-a-home-visiting-maternal-infant-attachment-intervention-delivered-by-community-health-workers-in-south-africa-reanalysis-of-a-randomized-controlled-trial
#13
Barak Morgan, Robert Kumsta, Pasco Fearon, Dirk Moser, Sarah Skeen, Peter Cooper, Lynne Murray, Greg Moran, Mark Tomlinson
BACKGROUND: Clear recognition of the damaging effects of poverty on early childhood development has fueled an interest in interventions aimed at mitigating these harmful consequences. Psychosocial interventions aimed at alleviating the negative impacts of poverty on children are frequently shown to be of benefit, but effect sizes are typically small to moderate. However, averaging outcomes over an entire sample, as is typically done, could underestimate efficacy because weaker effects on less susceptible individuals would dilute estimation of effects on those more disposed to respond...
February 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28236319/history-of-childhood-abuse-and-mother-infant-interaction-a-systematic-review-of-observational-studies
#14
Kyla Vaillancourt, Susan Pawlby, R M Pasco Fearon
Literature that has examined maternal self-reported history of abuse and an observational assessment of infant-mother interaction were reviewed. Electronic databases were searched, and studies that met predefined criteria were included. Fourteen (12 independent samples) studies were included and assessed for quality using the Effective Public Health Practice Project tool (National Collaborating Centre for Methods and Tools, 2008). Ten of the 14 studies found a direct or an indirect relationship between self-reported abuse and observed caregiving...
March 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28225511/treatment-satisfaction-in-systemic-lupus-erythematosus-development-of-a-patient-reported-outcome-measure
#15
Susan D Mathias, Pamela Berry, Katie Pascoe, Jane de Vries, Anca D Askanase, Hilary H Colwell, David J Chang
OBJECTIVE: The aim of this study was to develop a patient-reported outcome measure specific for systemic lupus erythematosus (SLE) to assess patient satisfaction with treatment, treatment options, and medical care. METHODS: Patients with SLE were recruited from four US rheumatology practices. Concept elicitation interviews identified aspects that patients considered important and relevant regarding satisfaction with treatment and medical care. Concept elicitation interviews and clinical input were used to draft the Lupus Satisfaction Questionnaire (LSQ)...
March 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28225146/effect-of-the-microstructure-of-the-functional-layers-on-the-efficiency-of-perovskite-solar-cells
#16
REVIEW
Fuzhi Huang, Alexander R Pascoe, Wu-Qiang Wu, Zhiliang Ku, Yong Peng, Jie Zhong, Rachel A Caruso, Yi-Bing Cheng
The efficiencies of the hybrid organic-inorganic perovskite solar cells have been rapidly approaching the benchmarks held by the leading thin-film photovoltaic technologies. Arguably, one of the most important factors leading to this rapid advancement is the ability to manipulate the microstructure of the perovskite layer and the adjacent functional layers within the device. Here, an analysis of the nucleation and growth models relevant to the formation of perovskite films is provided, along with the effect of the perovskite microstructure (grain sizes and voids) on device performance...
February 22, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28209459/progressive-subcortical-calcifications-secondary-to-venous-hypertension-in-an-intracranial-dural-arteriovenous-fistula
#17
Heather M Pascoe, Elaine H Lui, Peter Mitchell, Frank Gaillard
Intracranial dural arteriovenous fistulas (dAVF) are acquired lesions, with the most commonly reported findings on CT haemorrhage or focal oedema. We describe a case of progressive subcortical calcification on CT secondary to venous hypertension from a high grade dAVF.
February 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28209359/safety-and-efficacy-of-fimasartan-in-mexican-patients-with-grade-1-2-essential-hypertension
#18
Ernesto G Cardona-Muñoz, Agustín López-Alvarado, Ignacio Conde-Carmona, Gerardo Sánchez-Mejorada, Sara Pascoe-González, Ramiro G Banda-Elizondo, Armando García-Castillo, Guillermo González-Gálvez, Raúl G Velasco-Sánchez, Maricela Vidrio-Velázquez, José L Leiva-Pons, Efraín Villeda-Espinosa, Arturo Guerra-López, Ramón M Esturau-Santalo
OBJECTIVE: To evaluate efficacy and safety of 60mg and 120mg Fimasartan (FMS) alone or combined with 12.5mg hydrochlorothiazide (HCTZ) in Mexican population. METHODS: Six month, treat-to-target, open study in subjects with grade 1-2 hypertension. Subjects were initially treated with 60mg FMS once daily; on week 8, those with Diastolic Blood Pressure (DBP) <90mmHg continued on the same FMS dose during the rest of the study while those with DBP ≥90mmHg were randomized to either 120mg FMS or 60mg FMS+12...
February 10, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28207315/diagnosis-of-lumbosacral-diskospondylosis-in-a-bucking-bull-assisted-by-high-definition-thermal-and-nuclear-scintigraphic-imaging
#19
Marc Caldwell, Thomas Passler, Ram C Purohit, David Pascoe, Dwight F Wolfe
CASE DESCRIPTION An 8-year-old Brahman-cross bull was evaluated for left hind limb lameness of 2 months' duration. The lameness was first noticed during a rodeo bucking performance, immediately after the bull appeared to land inappropriately on the affected limb. CLINICAL FINDINGS Physical examination findings revealed left hind limb lameness, ataxia, and left-sided epaxial muscle atrophy. Palpation per rectum along the lumbar portion of the vertebral column revealed evidence of exostosis of the ventral aspect...
March 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28205536/genomic-structure-and-insertion-sites-of-helicobacter-pylori-prophages-from-various-geographical-origins
#20
Filipa F Vale, Alexandra Nunes, Mónica Oleastro, João P Gomes, Daniel A Sampaio, Raquel Rocha, Jorge M B Vítor, Lars Engstrand, Ben Pascoe, Elvire Berthenet, Samuel K Sheppard, Matthew D Hitchings, Francis Mégraud, Jamuna Vadivelu, Philippe Lehours
Helicobacter pylori genetic diversity is known to be influenced by mobile genomic elements. Here we focused on prophages, the least characterized mobile elements of H. pylori. We present the full genomic sequences, insertion sites and phylogenetic analysis of 28 prophages found in H. pylori isolates from patients of distinct disease types, ranging from gastritis to gastric cancer, and geographic origins, covering most continents. The genome sizes of these prophages range from 22.6-33.0 Kbp, consisting of 27-39 open reading frames...
February 16, 2017: Scientific Reports
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