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https://www.readbyqxmd.com/read/28637862/multicenter-registry-analysis-of-center-characteristics-associated-with-technique-failure-in-patients-on-incident-peritoneal-dialysis
#1
Htay Htay, Yeoungjee Cho, Elaine M Pascoe, Darsy Darssan, Annie-Claire Nadeau-Fredette, Carmel Hawley, Philip A Clayton, Monique Borlace, Sunil V Badve, Kamal Sud, Neil Boudville, Stephen P McDonald, David W Johnson
BACKGROUND AND OBJECTIVES: Technique failure is a major limitation of peritoneal dialysis. Our study aimed to identify center- and patient-level predictors of peritoneal dialysis technique failure. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: All patients on incident peritoneal dialysis in Australia from 2004 to 2014 were included in the study using data from the Australia and New Zealand Dialysis and Transplant Registry. Center- and patient-level characteristics associated with technique failure were evaluated using Cox shared frailty models...
June 21, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28633661/prevalence-of-arthritis-according-to-age-sex-and-socioeconomic-status-in-six-low-and-middle-income-countries-analysis-of-data-from-the-world-health-organization-study-on-global-ageing-and-adult-health-sage-wave-1
#2
Sharon L Brennan-Olsen, S Cook, M T Leech, S J Bowe, P Kowal, N Naidoo, I N Ackerman, R S Page, S M Hosking, J A Pasco, M Mohebbi
BACKGROUND: In higher income countries, social disadvantage is associated with higher arthritis prevalence; however, less is known about arthritis prevalence or determinants in low to middle income countries (LMICs). We assessed arthritis prevalence by age and sex, and marital status and occupation, as two key parameters of socioeconomic position (SEP), using data from the World Health Organization Study on global AGEing and adult health (SAGE). METHODS: SAGE Wave 1 (2007-10) includes nationally-representative samples of older adults (≥50 yrs), plus smaller samples of adults aged 18-49 yrs...
June 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28614843/elementary-school-teachers-vocal-dose-muscle-bioenergetics-and-training-implications
#3
Audrey G Smith, Mary J Sandage, David D Pascoe, Laura W Plexico, Italo R Lima, Guanqun Cao
Purpose: Translating exercise-science methodology for determination of muscle bioenergetics, we hypothesized that the temporal voice-use patterns for classroom and music teachers would indicate a reliance on the immediate energy system for laryngeal skeletal-muscle metabolism. It was hypothesized that the music-teacher group would produce longer voiced segments than the classroom teachers. Method: Using a between- and within-group multivariate analysis-of-variance design (5 classroom teachers; 7 music teachers), we analyzed fundamental-frequency data-collected via an ambulatory phonation monitor-for length (seconds) of voiced and nonvoiced intervals...
June 15, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28610112/the-weevil-genera-i-nyphaeba-i-pascoe-and-i-pantiala-i-pascoe-and-the-problems-of-an-unstable-nomenclature-in-orphaned-taxa
#4
Alexander Riedel
The genera Nyphaeba Pascoe and Pantiala Pascoe of Cryptorhynchinae are redescribed and revised. Lectotypes are designated for the names Nyphaeba monommoides Pascoe and Pantiala illusa Pascoe. This facilitates the description of Nyphaeba mimica sp. n. represented by two paralectotypes of Pantiala illusa. Both genera are excluded from the subtribe Tylodina Lacordaire based on their possession of wings and a distinct metanepisternum. The following new combination for a species originally described in Pantiala is proposed: Nyphaeba germari (Faust)...
March 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610006/three-new-species-of-i-psyrassa-i-pascoe-1866-coleoptera-cerambycidae-cerambycinae
#5
Antonio Santos-Silva, Juan Pablo Botero, Carlos Taboada-Verona
Currently, Psyrassa Pascoe, 1866 includes 37 species distributed mainly in southern United States to Central America (Monné 2016; Tavakilian and Chevillotte 2016). Only four species occur in northern South America: P. meridionalis Martins, 2005 (Ecuador); P. rufescens Nonfried, 1894 (Brazil); P. testacea Linsley, 1935 (Colombia, Venezuela, French Guiana); and P. subglabra Linsley, 1935 (Ecuador).
April 7, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609879/a-revision-of-the-new-zealand-weevil-genus-irenimus-pascoe-1876-coleoptera-curculionidae-entiminae
#6
Samuel D J Brown
The taxonomy of the New Zealand weevil genus Irenimus Pascoe, 1876 is revised, resulting in a narrower concept of the genus than has been considered in recent decades. In total, the genus now contains only seven species. In addition to the type species, I. parilis Pascoe, 1876, the genus contains I. duplex (Broun, 1904) and five newly described species: I. aniptus new species (type locality, Oamaru, DN), I. crinitus new species (type locality, Hakataramea Valley, SC), I. minimus new species (type locality, Alexandra, CO), I...
May 8, 2017: Zootaxa
https://www.readbyqxmd.com/read/28590023/unravelling-the-impact-of-early-life-exposures-on-lung-structure-and-function-in-the-developmental-origins-of-asthma
#7
EDITORIAL
Christopher D Pascoe
No abstract text is available yet for this article.
June 7, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28560269/fractures-in-indigenous-compared-to-non-indigenous-populations-a-systematic-review-of-rates-and-aetiology
#8
REVIEW
Sharon L Brennan-Olsen, Sara Vogrin, William D Leslie, Rita Kinsella, Maree Toombs, Gustavo Duque, Sarah M Hosking, Kara L Holloway, Brianna J Doolan, Lana J Williams, Richard S Page, Julie A Pasco, Shae E Quirk
BACKGROUND: Compared to non-indigenous populations, indigenous populations experience disproportionately greater morbidity, and a reduced life expectancy; however, conflicting data exist regarding whether a higher risk of fracture is experienced by either population. We systematically evaluate evidence for whether differences in fracture rates at any skeletal site exist between indigenous and non-indigenous populations of any age, and to identify potential risk factors that might explain these differences...
June 2017: Bone Reports
https://www.readbyqxmd.com/read/28538845/-spatial-analysis-of-gestational-anemia-in-peru-2015
#9
Akram Hernández-Vásquez, Diego Azañedo, Daniel A Antiporta, Sandra Cortés
Objectives: To establish regional prevalences of anemia in pregnant women receiving care at public clinics in Peru in 2015 and identify high-prevalence district conglomerates. Materials and Methods: An ecological study was carried out on data from pregnant women with anemia registered on the Nutritional Status Information System (SIEN) who received care in 7703 public clinics in 2015. Regional and district prevalences of gestational anemia were calculated. District conglomerates with a high prevalence of gestational anemia were identified using the Moran Index...
January 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28534669/reply-to-lipworth-and-jabbal-and-to-singh-and-vestbo
#10
David A Lipson, Helen Barnacle, Ruby Birk, Noushin Brealey, Nicholas Locantore, David A Lomas, Andrea Ludwig-Sengpiel, Rajat Mohindra, Maggie Tabberer, Chang-Qing Zhu, Steven J Pascoe
No abstract text is available yet for this article.
May 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28512055/first-plasma-and-tissue-pharmacokinetic-study-of-the-ysnsg-cyclopeptide-a-new-integrin-antagonist-using-microdialysis
#11
Florian Slimano, Zoubir Djerada, Salim Bouchene, Laurence Van Gulick, Sylvie Brassart-Pasco, Sylvain Dukic
The YSNSG peptide is a synthetic peptide targeting αvβ3 integrin. This peptide exhibits promising activity in vitro and in vivo against melanoma. To determine pharmacokinetic parameters and predictive active doses in the central nervous system (CNS) and subcutaneous tissue (SC), we conducted microdialysis coupled with pharmacokinetic modeling and Monte Carlo simulation. After a recovery period of surgical procedures, a microdialysis probe was inserted in the caudate and in subcutaneous tissue. Plasma samples and dialysates collected 5h after YSNSG intravenous administration (10mg/kg) were analyzed by UPLC-MS/MS...
May 13, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28493321/local-genes-for-local-bacteria-evidence-of-allopatry-in-the-genomes-of-transatlantic-campylobacter-populations
#12
Ben Pascoe, Guillaume Méric, Koji Yahara, Helen Wimalarathna, Susan Murray, Matthew D Hitchings, Emma L Sproston, Catherine D Carrillo, Eduardo N Taboada, Kerry K Cooper, Steven Huynh, Alison J Cody, Keith A Jolley, Martin C J Maiden, Noel D McCarthy, Xavier Didelot, Craig T Parker, Samuel K Sheppard
The genetic structure of bacterial populations can be related to geographical locations of isolation. In some species, there is a strong correlation between geographical distance and genetic distance, which can be caused by different evolutionary mechanisms. Patterns of ancient admixture in Helicobacter pylori can be reconstructed in concordance with past human migration, whereas in Mycobacterium tuberculosis it is the lack of recombination that causes allopatric clusters. In Campylobacter, analyses of genomic data and molecular typing have been successful in determining the reservoir host species, but not geographical origin...
May 10, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28478726/pattern-of-psychotropic-medication-use-over-two-decades-in-australian-women
#13
Amanda L Stuart, Mohammadreza Mohebbi, Julie A Pasco, Shae E Quirk, Sharon L Brennan-Olsen, Michael Berk, Lana J Williams
OBJECTIVE: Few population-based studies have been used to investigate secular trends in psychotropic medication use. Therefore, the aim of this study was to examine psychotropic medication use over time using data from the Geelong Osteoporosis Study, an on-going, population-based, cohort study of Australian women. METHODS: Of the 1494 women recruited at Time 1 (1993-1997), self-reported medication use from Time 2 (2004-2008) and/or Time 3 (2011-2014) was available for 889 women...
May 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28414852/-access-to-oral-health-services-in-children-under-twelve-years-of-age-in-peru-2014
#14
Akram Hernández-Vásquez, Diego Azañedo, Deysi Díaz-Seijas, Guido Bendezú-Quispe, Hugo Arroyo-Hernández, Stalin Vilcarromero, Andrés A Agudelo-Suárez
The aim of the study was to explore the patterns of dental health services access in children under twelve years of age in Peru. Data from 25,285 children under 12 years who participated in the Demographic and Family Health Survey of 2014 were reviewed. An exploratory spatial analysis was performed to project the proportions of children with access to dental health services, according to national regions, type of health service and urban or rural place of residence. The results show that of the total sample, 26...
July 2016: Salud Colectiva
https://www.readbyqxmd.com/read/28408714/association-between-peritoneal-glucose-exposure-and-peritonitis-in-peritoneal-dialysis-patients-the-balanz-trial
#15
Melissa Nataatmadja, Yeoungjee Cho, Elaine M Pascoe, Darsy Darssan, Carmel M Hawley, David W Johnson
♦Background: Glucose is the primary osmotic medium used in most peritoneal dialysis (PD) solutions, and exposure to glucose has been shown to exert detrimental effects both locally, at the peritoneal membrane, and systemically. Moreover, high dialysate glucose exposure may predispose patients to an increased risk of peritonitis, perhaps as a result of impaired host defences, vascular disease, and damage to the peritoneal membrane. ♦ Methods: In this post-hoc analysis of a multicenter, multi-national, open-label randomized controlled trial of neutral pH, low-glucose degradation product (GDP) versus conventional PD solutions (balANZ trial), the relationship between peritonitis rates of low (< 123...
April 13, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28401838/poverty-early-care-and-stress-reactivity-in-adolescence-findings-from-a-prospective-longitudinal-study-in-south-africa
#16
R M Pasco Fearon, Mark Tomlinson, Robert Kumsta, Sarah Skeen, Lynne Murray, Peter J Cooper, Barak Morgan
A considerable body of evidence suggests that early caregiving may affect the short-term functioning and longer term development of the hypothalamic-pituitary-adrenocortical axis. Despite this, most research to date has been cross-sectional in nature or restricted to relatively short-term longitudinal follow-ups. More important, there is a paucity of research on the role of caregiving in low- and middle-income countries, where the protective effects of high-quality care in buffering the child's developing stress regulation systems may be crucial...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28393350/randomised-trial-of-a-parent-mediated-intervention-for-infants-at-high-risk-for-autism-longitudinal-outcomes-to-age-3%C3%A2-years
#17
J Green, A Pickles, G Pasco, R Bedford, M W Wan, M Elsabbagh, V Slonims, T Gliga, E J H Jones, C H M Cheung, T Charman, M H Johnson
BACKGROUND: There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. METHODS: A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention...
April 10, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28384393/d-cysteine-ligands-control-metal-geometries-within-de-novo-designed-three-stranded-coiled-coils
#18
Leela Ruckthong, Anna F A Peacock, Cherilyn E Pascoe, Lars Hemmingsen, Jeanne A Stuckey, Vincent L Pecoraro
Although metal ion binding to naturally occurring l-amino acid proteins is well documented, understanding the impact of the opposite chirality (d-)amino acids on the structure and stereochemistry of metals is in its infancy. We examine the effect of a d-configuration cysteine within a designed l-amino acid three-stranded coiled coil in order to enforce a precise coordination number on a metal center. The d chirality does not alter the native fold, but the side-chain re-orientation modifies the sterics of the metal binding pocket...
April 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28375647/fulfil-trial-once-daily-triple-therapy-in-patients-with-chronic-obstructive-pulmonary-disease
#19
David A Lipson, Helen Barnacle, Ruby Birk, Noushin Brealey, Nicholas Locantore, David A Lomas, Andrea Ludwig-Sengpiel, Rajat Mohindra, Maggie Tabberer, Chang-Qing Zhu, Steven J Pascoe
RATIONALE: Randomized data comparing triple therapy with dual inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) therapy in patients with chronic obstructive pulmonary disease (COPD) are limited. OBJECTIVES: We compared the effects of once-daily triple therapy on lung function and health-related quality of life with twice-daily ICS/LABA therapy. METHODS: FULFIL was a randomized, double-blind, double-dummy study comparing 24 weeks of once-daily triple therapy (fluticasone furoate/umeclidinium/vilanterol 100 μg/62...
April 4, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28348870/bayesian-identification-of-bacterial-strains-from-sequencing-data
#20
Aravind Sankar, Brandon Malone, Sion C Bayliss, Ben Pascoe, Guillaume Méric, Matthew D Hitchings, Samuel K Sheppard, Edward J Feil, Jukka Corander, Antti Honkela
Rapidly assaying the diversity of a bacterial species present in a sample obtained from a hospital patient or an environmental source has become possible after recent technological advances in DNA sequencing. For several applications it is important to accurately identify the presence and estimate relative abundances of the target organisms from short sequence reads obtained from a sample. This task is particularly challenging when the set of interest includes very closely related organisms, such as different strains of pathogenic bacteria, which can vary considerably in terms of virulence, resistance and spread...
August 2016: Microbial Genomics
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