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infected mediastinitis

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https://www.readbyqxmd.com/read/28642818/nivolumab-as-salvage-treatment-in-a-patient-with-hiv-related-relapsed-refractory-hodgkin-lymphoma-and-liver-failure-with-encephalopathy
#1
Jose D Sandoval-Sus, Francis Mogollon-Duffo, Ankita Patel, Nathan Visweshwar, Damian A Laber, Richard Kim, Michael V Jagal
BACKGROUND: We report the first case to our knowledge of a patient with relapsed/refractory classical hodgkin lymphoma and liver failure with encephalopathy along with human immunodeficiency virus/acquired immunodeficiency syndrome infection, successfully treated with nivolumab without major side effects and encouraging prolonged disease control. CASE PRESENTATION: In December 2015, at the time of the patient's progression from his Hodgkin lymphoma after fourth line treatment, he developed persistent fevers, abdominal distension, jaundice and worsening of his liver function tests...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28636733/idiopathic-pretracheal-deep-neck-space-infection-with-mediastinal-extension-a-series-of-3-cases-and-review-of-the-literature
#2
Samuel Roberts, Lyndon Chan, Robert Eisenberg
Idiopathic pretracheal deep neck space infection is an extremely rare condition with potentially devastating complications. We present a series of 3 cases of pretracheal deep neck space infection that arose in the absence of trauma or a congenital lesion and that exhibited mediastinal spread. To the best of our knowledge, these cases represent the first reported series of this rare condition to be published in the English-language literature. All cultures grew Streptococcus milleri, and all patients had a favorable outcome...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28631657/citrobacter-freundii-as-a-cause-of-acute-suppurative-thyroiditis-in-an-immunocompetent-adult-female
#3
Gursimran Kaur Mohi, Priya Datta, Jagdish Chander, Arjun Das
Acute suppurative thyroiditis (AST) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. The most common cause of AST is bacterial, and the most common bacteria are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella species. Due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. Here, we describe a case of a 40-year-old female with AST caused by Citrobacter freundii...
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28618847/a-fatal-aortic-arch-rupture-due-to-descending-necrotizing-mediastinitis-in-a-24-year-old-woman
#4
Fabien Lareyre, Charlotte Cohen, Serge Declemy, Juliette Raffort, Hervé Quintard
Descending necrotizing mediastinitis (DNM) is a life-threatening disease which often develops from a purulent infection of the oral cavity and is associated with high rates of mortality. Here we report the case of a young patient who died from an aortic arch rupture in context of DNM developed from an odontogenic infection caused by Prevotella buccae. Based on the current knowledge on this very rare vascular complication, we discuss factors that may have contributed to this fatal issue and future issues to optimize care provided to patients...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28610889/high-resolution-ct-findings-of-pulmonary-tuberculosis-in-liver-transplant-patients
#5
R Schuhmacher Neto, I L Giacomelli, C Schuller Nin, J da Silva Moreira, A Comaru Pasqualotto, E Marchiori, K Loureiro Irion, B Hochhegger
AIM: To assess the high-resolution computed tomography (HRCT) findings in liver transplant patients diagnosed with pulmonary Mycobacterium tuberculosis infection. MATERIALS AND METHODS: The HRCT findings from 19 patients diagnosed with pulmonary tuberculosis infection after liver transplantation were reviewed. The patients included were 12 men and seven women, age range 23-65 years; mean age 57 years. The diagnosis was established with Mycobacterium tuberculosis detection in bronchoalveolar lavage, sputum, or biopsy...
June 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28610562/end-stage-renal-disease-a-risk-factor-of-deep-neck-infection-a-nationwide-follow-up-study-in-taiwan
#6
Geng-He Chang, Ming-Shao Tsai, Chia-Yen Liu, Meng-Hung Lin, Yao-Te Tsai, Cheng-Ming Hsu, Yao-Hsu Yang
BACKGROUND: Uremia is likely a risk factor for deep neck infection (DNI). However, only a few relevant cases have been reported, and evidence sufficient to support this hypothesis is lacking. The aim of the study is to investigate the effects of end-stage renal disease (ESRD) on DNI. METHODS: We used the database of the Registry for Catastrophic Illness Patients (RFCIP), a subset of the National Health Insurance Research Database (NHIRD) in Taiwan, to conduct a retrospective follow-up study...
June 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28592080/-complete-revascularization-for-multi-vessel-coronary-diseases-through-lower-ministernotomy-on-beating-heart-off-pump-surgery
#7
Z B Xiao, Y Zhang, J Z Guo, Y Y Li, Y P Zhang
Objective: To discuss a novel method of complete revascularization for multi-vessel coronary diseases on beating heart off-pump surgery through lower ministernotomy. Methods: Clinical data of 79 patients underwent ministernotomy off-pump coronary artery bypass from January 2015 to May 2016 at Department of Cardiac Surgery, Heart Center, Beijing Friendship Hospital, Capital Medical University were analyzed retrospectively. There were 62 male and 17 female patients, with an average age of (65±9) years. All the patients were multi-vessel coronary diseases and planned to receive coronary artery bypass grafting...
June 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28588368/two-cases-of-esophageal-injury-following-anterior-cervical-discectomy-and-fusion-one-overt-and-one-covert
#8
Prasad Krishnan, Rajaraman Kartikueyan, Sachinkumar Maheshbhai Patel, Partha Pratim Bose, Kanchan Kumar Mukherjee
Esophageal perforation is a dreaded complication of anterior cervical spinal surgery. A 52-year-old diabetic man had undergone a surgery for a C6-C7 disc prolapse and developed spiking fever with chills and rigor on the 7th postoperative day. No cause could be found out but a CT scan of thorax done in the course of investigations revealed pneumomediastimum. The patient succumbed on the 10th day after surgery. Autopsy revealed the cause of death to be mediastinitis following iatrogenic esophageal perforation...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28579789/a-retrograde-y-stenting-of-the-trachea-for-treatment-of-mediastinal-fistula-in-an-unusual-situation
#9
Wolfgang Hohenforst-Schmidt, Paul Zarogoulidis, Michael Steinheimer, Thomas Schneider, Naim Benhassen, Holger Rupprecht, Lutz Freitag
INTRODUCTION: Stents have been used for quite some time for the treatment of benign and malignant airway stenosis. Silicon stents are preferred for benign situations, whereas metallic self-expanding stents are preferred for malignant comorbidities. PATIENT AND METHODS: In general, stents can be placed in different approach directions, although in pulmonary medicine it is logical to apply only antegrade techniques - until now. A 63-year-old patient, 168 cm height and 53 kg weight on referral, suffered chronical diseases...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28556943/infected-mediastinal-bronchogenic-cyst-successfully-treated-by-eus-fna-drainage-via-esophagus
#10
I O Davarashvili, Yulia Epstein, Tawfik Khoury
A 61-year old female admitted with complaints of 10 days of productive cough and fever of 38 °C. She was started on antibiotics with oral cefuroxime 500 mg and azithromycin 500 mg. An X-Ray showed mediastinal mass with an air-fluid within. The patient was referred to our institution due to a suspicion of lung abscess. This article is protected by copyright. All rights reserved.
May 29, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28551896/-review-of-common-pathogens-in-the-bone-and-blood-cultures-and-antibiotic-treatment-in-patients-with-sternal-osteomyelitis
#11
Michal Benkler, Ori Shulman, Yoav Avrahamy, David Mendes, Yoav Arus, Ron Fishel, Amos Leviav, Dana Egozi
AIMS: This study concentrates on microbiological data collection of deep sternal wounds to delineate early and correct antibiotic therapy. BACKGROUND: Deep sternal wound infection, mediastinitis and sternal osteomyelitis are devastating and life-threatening complications of median-sternotomy incisions after cardiac surgical procedures. The incidence of surgical wound infection in sternotomies should be similar to that in any clean surgical procedure (i.e. approximately 2%)...
February 2017: Harefuah
https://www.readbyqxmd.com/read/28548623/pneumocystis-carinii-infection-with-severe-pneumomediastinum-and-lymph-node-involvement-in-a-whippet-mixed-breed-dog
#12
Christiane Weissenbacher-Lang, Andrea Fuchs-Baumgartinger, Andrea Klang, Sibylle Kneissl, Armin Pirker, Sarina Shibly, Stephanie von Ritgen, Herbert Weissenböck, Frank Künzel
A 3.5-y-old Whippet mixed-breed dog was presented with a history of respiratory distress, exercise intolerance, and generalized demodicosis. Hematologic alterations included marked leukocytosis and neutrophilia. Radiographic examination showed a diffuse interstitial and mild peripheral alveolar lung pattern and pneumomediastinum. Because the cytologic examination of the bronchoalveolar aspirate was not diagnostic and a persistent perforation of the upper respiratory tract could not be ruled out, the dog was submitted to thoracoscopy, and subsequently the left cranial lung lobe as well as mediastinal and sternal lymph nodes were resected...
May 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28538579/the-split-pectoralis-flap-combining-the-benefits-of-pectoralis-major-advancement-and-turnover-techniques-in-one-flap
#13
Rodger H Brown, Safa E Sharabi, Katarzyna E Kania, Larry H Hollier, Shayan A Izaddoost
BACKGROUND: The pectoralis major is a versatile flap used as an advancement or turnover flap for sternal wound treatment. The advancement flap provides suboptimal inferior sternal coverage and poorly fills mediastinal dead space. The turnover flap covers the inferior sternum and fills dead space but requires disinsertion of the muscle from the humerus, resulting in functional loss and cosmetic deformity. METHODS: The authors describe a new technique of splitting the pectoralis muscle along its fibers, using the superior portion as an advancement flap and the inferior portion as a turnover flap...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28528049/an-old-solution-for-a-new-problem-eloesser-flap-management-of-infected-defibrillator-patches
#14
Heidi B Schubmehl, Huan Huan Sun, Jessica S Donington, Deane E Smith, Eugene A Grossi
Cardiac surgery patients with infected implantable cardioverter defibrillator hardware face high morbidity with both surgical and nonoperative management options. We present a case of infected epicardial patch defibrillator leads in a patient with prohibitively high risk of death with open surgical removal. As a less morbid alternative, an Eloesser flap was used to convert his presenting mediastinal empyema necessitans into a chronic, manageable wound.
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28523179/a-case-of-video-assisted-thoracoscopic-resection-of-malignant-transformation-of-pulmonary-recurrent-respiratory-papillomatosis
#15
Dana A Dominguez, David T Martin, Jeffrey B Velotta
Recurrent respiratory papillomatosis (RRP) is a disease of the respiratory tract caused by infection with the human papillomavirus (HPV) and is characterized by multiple recurring papillomas throughout the respiratory tract. Although rare, extra laryngeal involvement carries the risk of malignant transformation in 3-7% of adults. We report the case of a patient with unmonitored juvenile onset RRP with pulmonary involvement found to have malignant transformation to squamous cell carcinoma (SCC). Incidentally found on chest radiography for mild chest wall trauma, she was found to have a large left lower lobe mass with pathology consistent with SCC...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28512099/mitral-valve-vegetation-diagnosed-with-oesophageal-ultrasound-with-bronchoscope-eus-b
#16
Ajoe John Kattoor, Yogita M Rochlani, Kevin Kuriakose, Nikhil K Meena
Oesophageal ultrasound with bronchoscope (EUS-B) is designed to evaluate mediastinal structures. We describe a case of a 78-year-old woman who presented with altered mental status for 2 weeks. CT head revealed a subacute infarct in the right middle cerebral artery distribution. She was also found to have a lung mass on chest imaging. EUS-B-guided fine needle aspiration demonstrated the presence of adenocarcinoma in station 7 lymph node and in the mass. Immunohistochemistry confirmed it to be a lung primary as the Thyroid Transcription Factor-1 (TTF-1) was strongly positive...
May 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28502887/open-surgical-treatment-of-secondary-aorto-esophageal-and-aortobronchial-fistula-after-thoracic-endovascular-aortic-repair-and-esophagocoloplasty-in-a-second-procedure
#17
Milos Sladojevic, Milos Bjelovic, Nikola Ilic, Perica Mutavdzic, Igor Koncar, Marko Dragas, Lazar Davidovic
INTRODUCTION: Aorto-esophageal (AEF) and aortobronchial fistula (ABF) after TEVAR are rare complications with catastrophic consequences without treatment. In this case report we presented a patient with AEF and ABF after TEVAR successfully treated with endograft explantation and replaced by Dacron graft followed by esophagectomy and left principal bronchus repairing. CASE REPORT: We report a patient with AEF and ABF after TEVAR who was evaluated due to dysphagia and chest pain followed by hematemesis and hemoptysis...
May 11, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28464950/illumina-miseq-16s-amplicon-sequence-analysis-of-bovine-respiratory-disease-associated-bacteria-in-lung-and-mediastinal-lymph-node-tissue
#18
Dayle Johnston, Bernadette Earley, Paul Cormican, Gerard Murray, David Anthony Kenny, Sinead Mary Waters, Mark McGee, Alan Kieran Kelly, Matthew Sean McCabe
BACKGROUND: Bovine respiratory disease (BRD) is caused by growth of single or multiple species of pathogenic bacteria in lung tissue following stress and/or viral infection. Next generation sequencing of 16S ribosomal RNA gene PCR amplicons (NGS 16S amplicon analysis) is a powerful culture-independent open reference method that has recently been used to increase understanding of BRD-associated bacteria in the upper respiratory tract of BRD cattle. However, it has not yet been used to examine the microbiome of the bovine lower respiratory tract...
May 2, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28460201/deep-sternal-wound-infections-a-severe-complication-after-cardiac-surgery
#19
A Morgante, F Romeo
Sternal Wound Infections (SWI) represent a dangerous complication after cardiac surgery entailing significantly longer hospital stays and worse short-term survival, especially in case of deep infections (DSWI) with the onset of osteomielitis or mediastinitis. The real incidence of SWI can be estimated between 0.25% and 10%; among the risk factors for sternal dehiscences after a longitudinal median sternotomy, several experiences underline the role of diabetes as an independent risk factor for post-operative infections, especially in patients affected by COPD with higher BMI...
January 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28458871/candida-parapsilosis-associated-with-cervical-necrotizing-fasciitis-and-descending-mediastinitis
#20
Chung-Ching Lee, Wing-Kei Choi, Jimmy Yu-Wai Chan
BACKGROUND: This report presents an immunocompetent lady suffering from Candida parapsilosis associated with polybacterial cervical necrotizing fasciitis and descending mediastinitis. A literature review and management of invasive candidiasis is discussed. METHODS: A 57-year-old healthy lady presented with cervical necrotizing fasciitis and descending mediastinitis. She was promptly managed with emergency debridement. Both blood and tissue culture yielded multiple microorganisms including C...
April 2017: Journal of Surgical Case Reports
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