Neoreview

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Although necrotizing enterocolitis is a leading cause of morbidity and mortality among preterm infants, its underlying pathophysiology is not fully understood. Gut dysbiosis, an imbalance between commensal and pathogenic microbes, in the preterm infant is likely a major contributor to the development of necrotizing enterocolitis. In this review, we will discuss the increasing use of probiotics in the NICU, an intervention aimed to mitigate alterations in the gut microbiome. We will review the existing evidence regarding the safety and effectiveness of probiotics, and their potential to reduce rates of necrotizing enterocolitis in preterm infants...

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Dopamine has been used for half a century in adult and pediatric patients for the treatment of hypotension, as well as for the theoretical prevention of acute kidney injury (AKI). Although activation of renal dopamine receptors leads to increased urine output, there is no evidence that low-dose dopamine reduces the incidence of AKI, need for dialysis, or death. Dopamine administration is also associated with multiple adverse effects, particularly in preterm infants. Despite the lack of evidence for its use, as well as the known adverse effects of dopamine, many neonatologists still use low-dose dopamine to prevent or treat AKI in neonates...

Vaccine hesitancy became an important topic in the public discourse and academic research during the COVID-19 pandemic, but its history is as long as the history of immunization. One can find the same determinants of vaccine hesitancy, though in variable proportions, since the 1721 Boston smallpox epidemic. We aim to describe several historical immunization moments and analyze them using the vaccine hesitancy framework of the "5Cs" (ie, confidence, complacency, constraints, risk calculation, and collective responsibility)...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Although necrotizing enterocolitis is a leading cause of morbidity and mortality among preterm infants, its underlying pathophysiology is not fully understood. Gut dysbiosis, an imbalance between commensal and pathogenic microbes, in the preterm infant is likely a major contributor to the development of necrotizing enterocolitis. In this review, we will discuss the increasing use of probiotics in the NICU, an intervention aimed to mitigate alterations in the gut microbiome. We will review the existing evidence regarding the safety and effectiveness of probiotics, and their potential to reduce rates of necrotizing enterocolitis in preterm infants...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Dopamine has been used for half a century in adult and pediatric patients for the treatment of hypotension, as well as for the theoretical prevention of acute kidney injury (AKI). Although activation of renal dopamine receptors leads to increased urine output, there is no evidence that low-dose dopamine reduces the incidence of AKI, need for dialysis, or death. Dopamine administration is also associated with multiple adverse effects, particularly in preterm infants. Despite the lack of evidence for its use, as well as the known adverse effects of dopamine, many neonatologists still use low-dose dopamine to prevent or treat AKI in neonates...

No abstract text is available yet for this article.

Vaccine hesitancy became an important topic in the public discourse and academic research during the COVID-19 pandemic, but its history is as long as the history of immunization. One can find the same determinants of vaccine hesitancy, though in variable proportions, since the 1721 Boston smallpox epidemic. We aim to describe several historical immunization moments and analyze them using the vaccine hesitancy framework of the "5Cs" (ie, confidence, complacency, constraints, risk calculation, and collective responsibility)...

No abstract text is available yet for this article.

No abstract text is available yet for this article.