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Sjogren ultrasound

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https://www.readbyqxmd.com/read/27900604/assessment-of-interstitial-lung-disease-in-sj%C3%A3-gren-s-syndrome-by-lung-ultrasound-a-pilot-study-of-correlation-with-high-resolution-chest-tomography
#1
Pablo Guisado Vasco, Gonzalo de Luna Cardenal, Isabel Martín Garrido, José Manuel Luque Pinilla, Guadalupe Fraile Rodríguez, Juan José Nava Mateo, Daniel Carnevalli Ruiz
The background of this study is to assess the accuracy of lung ultrasound (LUS) to diagnose interstitial lung disease (ILD) in Sjögren's syndrome (Sjs), in patients who have any alterations in pulmonary function tests (PFT) or respiratory symptoms. LUS was correlated with chest tomography (hrCT), considering it as the imaging gold standard technique to diagnose ILD. This is a pilot, multicenter, cross-sectional, and consecutive-case study. The inclusion criteria are ≥18 years old, Signs and symptoms: according to ACEG 2002 criteria, respiratory symptoms (dyspnea, cough), or any alterations in PFR...
November 29, 2016: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/27749218/serum-calprotectin-is-a-biomarker-of-carotid-atherosclerosis-in-patients-with-primary-sj%C3%A3-gren-s-syndrome
#2
Gabriela M Balarini, Eliana Zandonade, Leandro Tanure, Gilda A Ferreira, Wildner M Sardenberg, Érica V Serrano, Cleia C Dias, Túlio P Navarro, Hilde H Nordal, Piotr M Mydel, Johan G Brun, Karl A Brokstad, Eva Gerdts, Roland Jonsson, Valéria Valim
OBJECTIVES: We aimed to identify the association of carotid atherosclerosis with the traditional risk factors, disease features, cytokine profile, and calprotectin in patients with primary Sjögren's syndrome (pSS). METHODS: 63 primary pSS patients and 63 age- and sex-matched healthy controls underwent carotid ultrasound, clinical and laboratory examination. The presence of carotid plaques was taken as carotid atherosclerosis. The covariates of carotid atherosclerosis were identified in univariate and multivariate regressions...
September 8, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27738293/image-segmentation-and-machine-learning-for-detection-of-abdominal-free-fluid-in-focused-assessment-with-sonography-for-trauma-examinations-a-pilot-study
#3
Anna R Sjogren, Megan M Leo, James Feldman, Joseph T Gwin
The objective of this pilot study was to test the feasibility of automating the detection of abdominal free fluid in focused assessment with sonography for trauma (FAST) examinations. Perihepatic views from 10 FAST examinations with positive results and 10 FAST examinations with negative results were used. The sensitivity and specificity compared to manual classification by trained physicians was evaluated. The sensitivity and specificity (95% confidence interval) were 100% (69.2%-100%) and 90.0% (55.5%-99...
November 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27576331/how-is-the-ultrasound-in-rheumatology-used-implemented-and-applied-in-latin-american-centers-results-from-a-multicenter-study
#4
Marwin Gutierrez, Cristina Hernandez-Diaz, Lucio Ventura-Rios, Lina María Saldarriaga-Rivera, Santiago Ruta, Magaly Alva, Claudia Mora -Trujillo, Wilkerson Pérez, Henry Terrazas, Rodolfo Del Carmen Arape Toyo, Maritza Quintero, Carla Solano, Oscar Sedano Santiago, Janet Grisel Huamán Sotomayor, Cesar Cefferino, Guillermo E Py, Marcelo J Audisio, Walter Javier Spindler, Horacio Berman, Carla Airoldi, Rómulo Wong, Ana Laura Álvarez Del Castillo Araujo, Mario E Díaz, Carmen Cerón Villaquiran, Rubén Darío Mantilla, José Alexandre Mendonça, Inês Guimarães da Silveira, Aline Defaveri do Prado, Melissa Cláudia Bisi, Violeta Rosario, Jeannette Medrano-Sánchez, Roberto Muñoz-Louis, Ana Cecilia Lozada-Navarro, Araceli Bernal, Maribel Lozano, Carlos Pineda
This study aimed to perform an overview of how ultrasound (US) is being used, implemented, and applied in rheumatologic centers in Latin America (LA). A retrospective, multicenter 1-year experience study was undertaken. Eighteen centers from eight countries were involved. The following information were collected: demographic data, indication to perform an US examination, physician that required the examination, and the anatomical region required for the examination. A total of 7167 patients underwent an US examination...
August 30, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27528574/multiobserver-reliability-of-ultrasound-assessment-of-salivary-glands-in-patients-with-established-primary-sj%C3%A3-gren-syndrome
#5
Nemanja Damjanov, Vera Milic, Juan Carlos Nieto-González, Iustina Janta, Lina Martínez-Estupiñan, Belén Serrano, Carmen Mata, María Montoro, Denisa Stanciu, Jelena Marinković-Erić, Francisco Javier López-Longo, Luis Carreño, Esperanza Naredo
OBJECTIVE: To evaluate the multiobserver reliability of salivary gland ultrasonography (SGUS) for scoring greyscale (GS) parenchymal inhomogeneity and parenchymal color Doppler (CD) signal in patients with established primary Sjögren syndrome (pSS). METHODS: The study comprised 2 multiobserver reliability assessments in patients with pSS in 2 European centers. The first reliability exercise was performed on 24 patients with pSS and 8 controls who were independently evaluated with GS and CD US by 5 observers at the Institute of Rheumatology, Belgrade, Serbia...
October 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/26770534/cross-sectional-comparison-of-ultrasonography-scoring-systems-for-primary-sjogren-s-syndrome
#6
Dongfang Lin, Weiqiang Yang, Xinghua Guo, Junyan Cao, Qing Lv, Ou Jin, Yuqiong Wu, Jieruo Gu
To choose the best ultrasound scoring system for clinic practice, ultrasound was performed for 94 cases with suspected primary Sjogren's syndrome (pSS) and 3 US scoring systems created by Hocevar, Salaffi, Millic were employd to assess for bilateral parotid glands and submandibular glands. The US evaluation was blinded to the final diagnosis of pSS according to 2002 classification criteria. 44 cases were finally diagnosed with pSS, 14 were diagnosed with secondary Sjogren's syndrome, and 36 were diagnosed with Sicca syndromes...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26675053/the-usefulness-of-ultrasound-in-the-diagnostics-of-sj%C3%A3-gren-s-syndrome
#7
REVIEW
Fadhil Saied, Monika Włodkowska-Korytkowska, Maria Maślińska, Brygida Kwiatkowska, Wojciech Kunisz, Patrycja Smorawińska, Iwona Sudoł-Szopińska
Sjögren's syndrome is an autoimmune exocrinopathy which manifests itself with dryness of the eyes and the oral cavity. These symptoms comprise a so-called sicca syndrome (xerostomia and xerophthalmia). Two forms of this disease may be distinguished: primary Sjögren's syndrome which affects salivary glands and secondary Sjögren's syndrome with other autoimmune diseases present such as rheumatoid arthritis, systemic lupus erythematosus or systemic scleroderma. The diagnosis is based on the classification criteria established in 2002 by a group of American and European scientists (American-European Consensus Group), which involve the interview and physical examination as well as serological, histopathological and radiological tests...
June 2013: Journal of Ultrasonography
https://www.readbyqxmd.com/read/26673524/the-usefulness-of-ultrasound-in-the-diagnostics-of-sj%C3%A3-grens-s-syndrome
#8
Marcin Szkudlarek
No abstract text is available yet for this article.
December 2013: Journal of Ultrasonography
https://www.readbyqxmd.com/read/26660860/ultrasound-of-the-salivary-glands-is-a-strong-predictor-of-labial-gland-biopsy-histopathology-in-patients-with-sicca-symptoms
#9
Elisa Astorri, Nurhan Sutcliffe, Polly S Richards, Krishna Suchak, Costantino Pitzalis, Michele Bombardieri, Anwar R Tappuni
BACKGROUND: The international classification criteria for Sjögren's syndrome necessitate the presence of either extractable nuclear antibody or a characteristic focal inflammatory infiltrate in a minor salivary gland. Thus, patients who are extractable nuclear antibody-negative will need to have a labial salivary gland biopsy, which is an invasive procedure associated with morbidity. The aim of this study was to evaluate the viability of ultrasound imaging of the major salivary glands as a predictor of the histology to explore whether ultrasound can help in stratifying Sjögren's patients and reduce the need for biopsy...
July 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/26626630/focal-myositis-presenting-as-pseudothrombophlebitis-of-the-arm
#10
REVIEW
Susana Roverano, Alberto Ortiz, Sergio Paira
We described a 21-year-old woman with a diagnosis of Sjögren syndrome that came for consultation with a localized mass over her left arm of fast growth. Lab results were normal; a Doppler ultrasound showed the presence of partial thrombosis in the left axillary vein; a magnetic resonance imaging showed edema on the biceps muscle and the biopsy of the mass disclosed the presence of severe lymphocyte infiltrate within the connective tissue and scarce muscle fibers. Immunostaining showed positive results for antígeno comun leucocitario in spanish (leukocyte common antigen) (ACL) and CD3...
April 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/26608250/-clinical-usefulness-of-salivary-gland-ultrasonography-in-sj%C3%A3-gren-s-syndrome-where-are-we-now
#11
D Cornec, V Devauchelle-Pensec, A Saraux, S Jousse-Joulin
Salivary gland ultrasonography is a simple, noninvasive and inexpensive procedure, which provides valuable information for the diagnosis of primary Sjögren's syndrome (pSS). The main sonographic characteristic of the major salivary glands (parotid and submandibular) in pSS patients is the heterogeneity of the parenchyma, with the appearance of hypoechoic areas. Numerous studies published over the past 20 years report a sensitivity of 70% and a specificity of more than 90% for the diagnosis of pSS. Before the widespread use of this procedure in daily practice and its integration into classification criteria of the disease, it has yet to be validated in terms of reproducibility and a consensus score should be established...
March 2016: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/26445930/low-intensity-pulsed-ultrasound-rescues-insufficient-salivary-secretion-in-autoimmune-sialadenitis
#12
Minami Sato, Shingo Kuroda, Karima Qurnia Mansjur, Ganzorig Khaliunaa, Kumiko Nagata, Shinya Horiuchi, Toshihiro Inubushi, Yoshiko Yamamura, Masayuki Azuma, Eiji Tanaka
INTRODUCTION: Low-intensity pulsed ultrasound (LIPUS) has been known to promote bone healing by nonthermal effects. In recent studies, LIPUS has been shown to reduce inflammation in injured soft tissues. Xerostomia is one of the most common symptoms in Sjögren syndrome (SS). It is caused by a decrease in the quantity or quality of saliva. The successful treatment of xerostomia is still difficult to achieve and often unsatisfactory. The aim of this study is to clarify the therapeutic effects of LIPUS on xerostomia in SS...
2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/26374590/mediastinal-sarcoidosis-diagnosed-by-endobronchial-ultrasound-in-a-patient-with-sj%C3%A3-gren-s-syndrome
#13
Augusto Carbonari, Marco Camunha, Fabio Marioni, Mauro Saieg, Lucio Rossini
No abstract text is available yet for this article.
July 2015: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/26368934/which-and-how-many-patients-should-be-included-in-randomised-controlled-trials-to-demonstrate-the-efficacy-of-biologics-in-primary-sj%C3%A3-gren-s-syndrome
#14
Valérie Devauchelle-Pensec, Jacques-Eric Gottenberg, Sandrine Jousse-Joulin, Jean-Marie Berthelot, Aleth Perdriger, Eric Hachulla, Pierre Yves Hatron, Xavier Puechal, Véronique Le Guern, Jean Sibilia, Laurent Chiche, Vincent Goeb, Olivier Vittecoq, Claire Larroche, Anne Laure Fauchais, Gilles Hayem, Jacques Morel, Charles Zarnitsky, Jean Jacques Dubost, Philippe Dieudé, Jacques Olivier Pers, Divi Cornec, Raphaele Seror, Xavier Mariette, Emmanuel Nowak, Alain Saraux
OBJECTIVE: The goal of this study was to determine how the choice of the primary endpoint influenced sample size estimates in randomised controlled trials (RCTs) of treatments for primary Sjögren's syndrome (pSS). METHODS: We reviewed all studies evaluating biotechnological therapies in pSS to identify their inclusion criteria and primary endpoints. Then, in a large cohort (ASSESS), we determined the proportion of patients who would be included in RCTs using various inclusion criteria sets...
2015: PloS One
https://www.readbyqxmd.com/read/26245278/il-17-sequestration-via-salivary-gland-gene-therapy-in-a-mouse-model-of-sjogren-s-syndrome-suppresses-disease-associated-expression-of-the-putative-autoantigen-klk1b22
#15
Changgong Wu, Zhimin Wang, Lee Zourelias, Hiteshi Thakker, Michael J Passineau
INTRODUCTION: IL-17 has a putative role in the pathophysiology of Sjogren's syndrome (SS) and has been shown to be upregulated in the salivary glands of affected individuals. Sequestration of IL-17 with Adenoviral-mediated gene therapy has previously shown a benefit upon the SS-like phenotype in the Aec1/Aec2 mouse model. We sought to understand the proteomic consequences of IL-17 sequestration in the salivary gland of this mouse model as a means of illuminating the role of IL-17 in SS-like disease...
2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/26181602/gastric-crystal-storing-histiocytosis-detected-with-asymptomatic-sj%C3%A3-gren-s-syndrome-report-of-a-case-and-summary
#16
Yutaka Yano, Takashi Nagahama, Toshiyuki Matsui, Kenta Chuman, Masao Takeichi, Fumihito Hirai, Kenshi Yao, Nobuaki Nishimata, Seiji Haraoka, Akinori Iwashita
Crystal-storing histiocytosis (CSH) localized to the stomach is very rare, with only two cases reported to date. The present patient was a 55-year-old woman with no noteworthy symptoms. An area of discoloration was seen in the greater curvature of the gastric body on upper endoscopy by a local physician, and CSH was strongly suspected on biopsy examination. On upper endoscopy performed at our hospital, a flat, whitish, finely granular membrane with a diameter of 10 mm was seen in the greater curvature of the gastric body on white light observation...
June 2013: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/26149284/advances-in-salivary-gland-gene-therapy-oral-and-systemic-implications
#17
REVIEW
Bruce J Baum, Ilias Alevizos, John A Chiorini, Ana P Cotrim, Changyu Zheng
INTRODUCTION: Much research demonstrates the feasibility and efficacy of gene transfer to salivary glands. Recently, the first clinical trial targeting a salivary gland was completed, yielding positive safety and efficacy results. AREAS COVERED: There are two major disorders affecting salivary glands: radiation damage following treatment for head and neck cancers and Sjögren's syndrome (SS). Salivary gland gene transfer has also been employed in preclinical studies using transgenic secretory proteins for exocrine (upper gastrointestinal tract) and endocrine (systemic) applications...
2015: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/26022533/salivary-gland-ultrasonography-a-highly-specific-tool-for-the-early-diagnosis-of-primary-sj%C3%A3-gren-s-syndrome
#18
COMPARATIVE STUDY
Chiara Baldini, Nicoletta Luciano, Gaia Tarantini, Rachele Pascale, Francesca Sernissi, Marta Mosca, Davide Caramella, Stefano Bombardieri
INTRODUCTION: Recently, a great interest has arisen for salivary gland ultrasonography (SGUS) as a valuable tool for the assessment of major salivary gland involvement in primary Sjögren's syndrome (pSS. The aims of this study were to test the accuracy of SGUS for the early detection of pSSand to compare the diagnostic performance of SGUS with minor salivary gland biopsy (MSGB) and unstimulated salivary flow (USFR) in this context. METHOD: Patients with suspected pSS and symptoms duration of ≤5 years were consecutively enrolled in this study...
May 28, 2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/25988616/diagnostic-properties-of-ultrasound-of-major-salivary-glands-in-sj%C3%A3-gren-s-syndrome-a-meta-analysis
#19
K Delli, P U Dijkstra, A J Stel, H Bootsma, A Vissink, F K L Spijkervet
OBJECTIVE: To perform a systematic review and meta-analysis on studies examining the properties of ultrasonography of major salivary glands for diagnosing Sjögren's syndrome. MATERIALS AND METHODS: We searched for the literature on eight databases. The quality of included articles was assessed with the QUADAS-2 tool. Publication bias, pooled sensitivity, specificity, diagnostic odds ratio, and 95% confidence intervals (95%CI) were calculated. Meta-regression analysis was performed...
September 2015: Oral Diseases
https://www.readbyqxmd.com/read/25926425/subclinical-articular-involvement-in-primary-sj%C3%A3-gren-s-syndrome-assessed-by-ultrasonography-and-its-negative-association-with-anti-centromere-antibody
#20
Takanori Fujimura, Takashi Fujimoto, Ryota Hara, Naoki Shimmyo, Yasunori Kobata, Akira Kido, Yasuhiro Akai, Yasuhito Tanaka
OBJECTIVES: To evaluate the subclinical articular involvement in patients with primary Sjögren's syndrome (pSS) using musculoskeletal ultrasound (MSUS), and to correlate the findings with laboratory results and clinical manifestations. METHODS: Forty-eight consecutive patients with pSS were enrolled. The bilateral metacarpophalangeal, proximal interphalangeal, and interphalangeal joints were examined using MSUS, and the synovial hypertrophy and power Doppler signal were recorded for each joint using semi-quantitative scores (0 = normal, 1 = mild change compared with undamaged joint, 2 = moderate change, and 3 = severe change)...
2015: Modern Rheumatology
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