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Hot flashes in females

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https://www.readbyqxmd.com/read/28531316/a-comprehensive-method-to-quantify-adaptations-by-male-and-female-mice-with-hot-flashes-induced-by-the-neurokinin-b-receptor-agonist-senktide
#1
Ashley A Krull, Sarah A Larsen, Donald K Clifton, Genevieve Neal-Perry, Robert A Steiner
Vasomotor symptoms (VMS, or hot flashes) plague millions of reproductive age men and women who have natural or iatrogenic loss of sex steroid production. Many affected individuals are left without treatment options because of contraindications to hormone replacement therapy and the lack of equally effective non-hormonal alternatives. Moreover, development of safer, more effective therapies has been stymied by the lack of an animal model that recapitulates the hot flash phenomenon and enables direct testing of hypotheses regarding the pathophysiology underlying hot flashes...
May 22, 2017: Endocrinology
https://www.readbyqxmd.com/read/28488202/autonomic-control-of-body-temperature-and-blood-pressure-influences-of-female-sex-hormones
#2
REVIEW
Nisha Charkoudian, Emma C J Hart, Jill N Barnes, Michael J Joyner
Female reproductive hormones exert important non-reproductive influences on autonomic regulation of body temperature and blood pressure. Estradiol and progesterone influence thermoregulation both centrally and peripherally, where estradiol tends to promote heat dissipation, and progesterone tends to promote heat conservation and higher body temperatures. Changes in thermoregulation over the course of the menstrual cycle and with hot flashes at menopause are mediated by hormonal influences on neural control of skin blood flow and sweating...
May 9, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28331462/a-case-of-malignant-pheochromocytoma-presenting-7-years-after-the-initial-surgery
#3
Larsa Al-Omaishi, Jonathan Babin, Ralph L Corsetti
BACKGROUND: Pheochromocytoma (PHEO) is a rare tumor of the adrenal medulla and sympathetic ganglion that produces the catecholamines norepinephrine and epinephrine. Traditionally, approximately 10% of PHEOs were thought to be malignant, but recent developments in PHEO research have noted that specific genetic mutations are associated with higher risk of metastatic spread. CASE REPORT: We report the case of a 71-year-old female who presented with abdominal pain in September 2009 when she was 64 years old...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28219672/changes-in-cardiovascular-function-based-on-adrenalin-and-norepinephrine-metabolism-in-ovariectomized-rats
#4
Hai Jiang, Wenpei Bai, Wenjuan Wang, Jing Zhang, Ke Wang, Yao Liu, Shuya Liu, Jing Jia, Lihua Qin
Menopause is a cardiovascular risk factor in women, and cardiovascular changes during perimenopause can increase the risk. We observed the influence of plasma adrenalin and norepinephrine and their metabolites on the cardiovascular system and the rectification effect of estrogen in ovariectomized rats. Fifty-four adult female Sprague-Dawley rats were randomly divided into sham (Sham), ovariectomized (OVX), or ovariectomized+estrogen treatment groups (OVX+E), with 18 rats in each. The Sham and OVX groups were given normal saline and the OVX+E group was given estradiol valerate beginning 2weeks after ovariectomy and continuing for 4weeks...
May 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28156437/integrative-oncology-consultation-and-symptom-palliation-analysis-of-patient-reported-outcomes-at-a-comprehensive-cancer-center
#5
Jennifer Leigh McQuade, Richard T Lee, Jane Williams, Amy Spelman, Bryan Fellman, Yisheng Li, Eduardo Bruera, Lorenzo Cohen
84 Background: Patients (pts) receiving cancer care are increasingly interested in complementary health approaches to improve symptoms and quality of life. We report on demographics and patient reported outcomes in an integrative oncology (IO) clinic. METHODS: Pts presenting for IO consultation or follow-up completed: Measure Yourself Concerns and Wellbeing (MYCaW), Edmonton Symptom Assessment Scale (ESAS), Short Form 12 (SF-12) quality of life (QOL) scale, and an overall satisfaction questionnaire...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28054115/-risk-and-benefit-of-nutritional-supplements-for-the-treatment-of-postmenopausal-complaints
#6
Patrick Diel, Anne Kurrat, Christina Oden, Lars Hanke
Menopause is for many females associated with an occurrence of a variety of health complaints and a decrease in quality in life. Hot flashes, sleep disturbances and a variety of other symptoms result in a strong psychological strain. Hormone replacement therapy for treatment of climacteric complaints is discussed controversially regarding associated side effects. This is a major reason to propose treatment with plant derived extracts and compounds as an alternative. Such compounds are available either as drugs but mostly as nutritional supplements...
January 4, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27760084/effect-of-gua-sha-therapy-on-perimenopausal-syndrome-a-randomized-controlled-trial
#7
Fang Meng, Pei-Bei Duan, Junya Zhu, Qing-Qing Lou, Zhao-Hui Fang, Hong-Li An, Lan-Ying Liu, Yue Hu, Qian Hu
OBJECTIVE: This study aims to evaluate the effectiveness and safety of Gua sha therapy on perimenopausal symptoms, quality of life, and serum female hormones in participants with perimenopausal syndrome. METHODS: A prospective, randomized, controlled clinical trial was conducted at the First Affiliated Hospital of Nanjing University of Chinese Medicine in China. Eighty women with perimenopausal syndrome were recruited and randomized into an intervention group or a control group...
October 10, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27619737/the-middle-aged-ovariectomized-marmoset-callithrix-jacchus-as-a-model-of-menopausal-symptoms-preliminary-evidence
#8
Nicole J Gervais, Shaun S Viechweg, Jessica A Mong, Agnès Lacreuse
Menopausal women often suffer from hot flashes and sleep disturbances that significantly impact their quality of life. Both human and animal studies suggest that loss of estrogens during menopause contribute to these symptoms. In the female rat, both core body temperature (CBT) and sleep are sensitive to 17β-estradiol (E2) levels, but important differences between the rat and the human patterns limit the interpretation of the results. The sleep and thermoregulation of the common marmoset (Callithrix jacchus) more closely resemble human patterns...
November 19, 2016: Neuroscience
https://www.readbyqxmd.com/read/27585723/anxiety-reduction-among-breast-cancer-survivors-receiving-hypnotic-relaxation-therapy-for-hot-flashes
#9
Alisa J Johnson, Joel Marcus, Kimberly Hickman, Debra Barton, Gary Elkins
Anxiety is common among breast-cancer survivors. This analysis examined the effect of a hypnotic relaxation therapy, developed to reduce hot flashes, on anxiety levels of female breast-cancer survivors. Anxiety was assessed using a numeric analog scale and the Hospital Anxiety and Depression Scale-Anxiety subscale. Significant reductions in anxiety were found from pre- to postintervention for each weekly session and were predictive of overall reductions in anxiety from baseline to after the last intervention...
October 2016: International Journal of Clinical and Experimental Hypnosis
https://www.readbyqxmd.com/read/27327802/use-of-plant-based-therapies-and-menopausal-symptoms-a-systematic-review-and-meta-analysis
#10
REVIEW
Oscar H Franco, Rajiv Chowdhury, Jenna Troup, Trudy Voortman, Setor Kunutsor, Maryam Kavousi, Clare Oliver-Williams, Taulant Muka
IMPORTANCE: Between 40% and 50% of women in Western countries use complementary therapies to manage menopausal symptoms. OBJECTIVE: To determine the association of plant-based therapies with menopausal symptoms, including hot flashes, night sweats, and vaginal dryness. DATA SOURCES: The electronic databases Ovid MEDLINE, EMBASE, and Cochrane Central were systematically searched to identify eligible studies published before March 27, 2016. Reference lists of the included studies were searched for further identification of relevant studies...
June 21, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27184535/anti-m%C3%A3-llerian-hormone-in-female-adolescent-cancer-patients-before-during-and-after-completion-of-therapy-a-pilot-feasibility-study
#11
Abha A Gupta, Amy Lee Chong, Catherine Deveault, Jeffrey Traubici, Anne Marie Maloney, Samantha Knight, Armando Lorenzo, Lisa Allen
STUDY OBJECTIVE: Alkylating agents are implicated in premature ovarian insufficiency. To optimize counseling regarding future ovarian function in survivors of adolescent cancer, we describe anti-Müllerian hormone (AMH) levels in female adolescents at diagnosis, during, and shortly after completion of chemotherapy. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: This was a prospective single-institution study. Participants were a mixed population of newly diagnosed postmenarchal female adolescents with malignancy...
December 2016: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27152312/assessment-of-menopausal-symptoms-among-early-and-late-menopausal-midlife-bangladeshi-women-and-their-impact-on-the-quality-of-life
#12
Kawsar Ahmed, Papia Jahan, Israt Nadia, Farzana Ahmed, Abdullah-Al-Emran
OBJECTIVES: Every physical abnormal criterion has an impact on the health. Late menopause causes different physiological problems which alike early menopause. The research interest is associated with both early and late menopausal women of Bangladesh as only few menopausal studies available in South East Asia especially in Bangladesh. The aims of this study are not only to assess the symptoms of menopausal abnormality but also to determine the impact of these symptoms on the quality of life (QOL) of the female society in Bangladesh...
April 2016: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/27062801/-systematic-evaluation-of-clinical-application-of-dingkun-dan
#13
REVIEW
Yan-xia Chen, Kun Ma
Dingkun Dan is a representative of the classic gynecological medicine. With Tonifying the liver and kidney, supplementing Qi and nourishing blood, regulating menstruation Shuyu, promoting the role of pain. Used in treatment of liver and kidney deficiency, deficiency of both qi and blood, Qi stagnation and blood stasis caused by irregular menstruation, menstrual pain, uterine bleeding, leukorrhea with reddish discharge, bruise blood removal, infertility, and various postpartum deficiency and bone steaming hot flashes of gynecological common disease...
October 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/27024401/ask-the-doctor-i-am-76-years-old-and-still-get-hot-flashes-is-it-true-that-women-who-have-hot-flashes-many-years-after-menopause-are-more-likely-to-experience-heart-problems-than-those-whose-symptoms-end-early-in-menopause
#14
https://www.readbyqxmd.com/read/27015968/informing-hot-flash-treatment-decisions-for-breast-cancer-survivors-a-systematic-review-of-randomized-trials-comparing-active-interventions
#15
REVIEW
Claire Johns, Susan M Seav, Sally A Dominick, Jessica R Gorman, Hongying Li, Loki Natarajan, Jun James Mao, H Irene Su
Patient-centered decision making about hot flash treatments often incorporates a balance of efficacy and side effects in addition to patient preference. This systematic review examines randomized controlled trials (RCTs) comparing at least two non-hormonal hot flash treatments in breast cancer survivors. In July 2015, PubMed, SCOPUS, CINAHL, Cochrane, and Web of Science databases were searched for RCTs comparing active, non-hormonal hot flash treatments in female breast cancer survivors. Thirteen trials were included after identifying 906 potential studies...
April 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/26765933/hypothalamic-orexin-s-role-in-exacerbated-cutaneous-vasodilation-responses-to-an-anxiogenic-stimulus-in-a-surgical-menopause-model
#16
Lauren M Federici, Izabela Facco Caliman, Andrei I Molosh, Stephanie D Fitz, William A Truitt, Pascal Bonaventure, Janet S Carpenter, Anantha Shekhar, Philip L Johnson
Distressing symptoms such as hot flashes and sleep disturbances affect over 70% of women approaching menopause for an average of 4-7 years, and recent large cohort studies have shown that anxiety and stress are strongly associated with more severe and persistent hot flashes and can induce hot flashes. Although high estrogen doses alleviate symptoms, extended use increases health risks, and current non-hormonal therapies are marginally better than placebo. The lack of effective non-hormonal treatments is largely due to the limited understanding of the mechanisms that underlie menopausal symptoms...
March 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/26753476/soy-isoflavones-inulin-calcium-and-vitamin-d3-in-post-menopausal-hot-flushes-an-observational-study
#17
A Cianci, N Colacurci, A M Paoletti, A Perino, E Cicinelli, S Maffei, M Di Martino, R Daguati, M Stomati, M Pilloni, S G Vitale, E Ricci, F Parazzini
PURPOSE OF INVESTIGATION: To evaluate the effect of soy isoflavones and inulin (SII) on hot flushes (HF) and quality of life in a clinical setting, the authors conducted an observational study. MATERIALS AND METHODS: The authors performed an observational, prospective, multicentric study on women in peri-/post-menopause treated or untreated with a product present on the Italian market, consisting in a mixture of calcium (500 mg), vitamin D3 (300 IU), inulin (3 g) and soy isoflavones (40 mg)...
2015: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26742879/safety-and-effectiveness-of-endovenous-laser-ablation-combined-with-ligation-for-severe-saphenous-varicose-veins-in-japanese-patients
#18
Masafumi Izumi, Yuichi Ikeda, Hiroharu Yamashita, Yoshinari Asaoka, Mitsuhiro Fujishiro, Masahiro Shin, Yoshihisa Abo
Endovenous laser ablation (EVLA), which is a relatively new therapeutic option for saphenous varicose veins of the legs, is less invasive than conventional stripping surgery with ligation. In this study, we evaluated the safety and effectiveness of EVLA combined with ligation for severe saphenous varicose veins that were graded as ≥ C4 by the CEAP classification. We treated 119 Japanese patients (141 limbs) between July 2005 and December 2007 utilizing a 1320-nm Nd:YAG laser. The obliteration rate of the treated veins was found to be 100% over the entire follow-up period (2...
2016: International Heart Journal
https://www.readbyqxmd.com/read/26677587/-correlation-between-intensity-of-menopausal-symptoms-and-cognitive-domain-assessed-with-cns-vs-tests
#19
Iwona Bojar, Alfred Owoc, Mariusz Witczak, Beata Pięta
INTRODUCTION: Numerous publications suggest that many cognitive domains deteriorate with age. As far as postmenopausal women are concerned, the question remains whether the process is caused only by an ageing brain or also by the menopause. The objective of this research was to analyze a possible correlation between intensity and duration of menopausal symptoms and the level of cognitive domains measured with CNS-VS tests among post-menopausal women. METHODOLOGY: The group under examination included 383 postmenopausal women (at least 2 years after their last menstruation) from South-Eastern Poland...
October 2015: Ginekologia Polska
https://www.readbyqxmd.com/read/26625564/estradiol-the-emerging-evidence-for-a-protective-role-against-insulin-resistance-and-obesity
#20
Bruce Biundo, Margaret Gogola
Estrogen therapy is a well-known and commonly used symptomatic treatment of hot flashes, night sweats and vaginal dryness associated with menopause. The most active estrogen, estradiol, is also understood to have a protective effect against osteoporosis. Like many hormones, though, estradiol has many roles in the body, both in males and females, and studies of these roles continue to emerge. A major function of estradiol involves obesity, insulin resistance, and cardiovascular disease; studies have shown the beneficial effects of estradiol in these areas, and this is somewhat at variance with traditional belief...
July 2015: International Journal of Pharmaceutical Compounding
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