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https://www.readbyqxmd.com/read/29245097/inverted-v-shaped-high-tibial-osteotomy-for-severe-tibia-vara-associated-with-turner-syndrome-a-case-report-and-review-of-literature
#1
Daisuke Abe, Satoshi Hamai, Ken Okazaki, Masato Yoshimoto, Takashi Komatsu, Yasuharu Nakashima
INTRODUCTION: Severe cases of genu varum represent a major challenge in obtaining normal configuration of the proximal tibia and overall limb alignment. PRESENTATION OF CASE: We performed inverted V-shaped high tibial osteotomy (HTO) by using a locking plate for recurrent severe bilateral tibia vara in a 15-year-old female patient with Turner syndrome. Preoperative medial proximal tibial angle (MPTA) and standing femorotibial angle (FTA) of the right/left legs were 67°/69° and 197°/203°, respectively...
December 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29244812/optimal-occlusion-uniformly-partitions-red-blood-cells-fluxes-within-a-microvascular-network
#2
Shyr-Shea Chang, Shenyinying Tu, Kyung In Baek, Andrew Pietersen, Yu-Hsiu Liu, Van M Savage, Sheng-Ping L Hwang, Tzung K Hsiai, Marcus Roper
In animals, gas exchange between blood and tissues occurs in narrow vessels, whose diameter is comparable to that of a red blood cell. Red blood cells must deform to squeeze through these narrow vessels, transiently blocking or occluding the vessels they pass through. Although the dynamics of vessel occlusion have been studied extensively, it remains an open question why microvessels need to be so narrow. We study occlusive dynamics within a model microvascular network: the embryonic zebrafish trunk. We show that pressure feedbacks created when red blood cells enter the finest vessels of the trunk act together to uniformly partition red blood cells through the microvasculature...
December 15, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29243933/new-aspects-of-the-gold-nanorod-formation-mechanism-via-seed-mediated-methods-revealed-by-md-simulations
#3
Jos Eacute Silva, Mario Roberto Meneghetti
New aspects of the formation and growth mechanism of gold nanorods (AuNRs) during seed-mediated colloidal synthesis are revealed from the results of molecular dynamics simulations. The model systems consist of cetyltrimethylammonium bromide (CTAB) units adsorbed on low-index (Au(110), Au(100) and Au(111)) and high-index (Au(250)) gold surfaces. The CTAB units are adsorbed as adjacent cylindrical micelles when the relative number of adsorbed bromide ions is small. At later AuNR growth stages, the number of bromide ions increases as the [AuBr2]- species pass through the channels between the adsorbed micelles on the gold surface...
December 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29243668/chemotactic-droplet-swimmers-in-complex-geometries
#4
Chenyu Jin, Babak Vajdi Hokmabad, Kyle Anthony Baldwin, Corinna Charlotte Maass
Chemotaxis and auto-chemotaxis are key mechanisms in the dynamics of micro-organisms, e.g. in the acquisition of nutrients and in the communication between individuals, influencing the collective behaviour. However, chemical signalling and the natural environment of biological swimmers are generally complex, making them hard to access analytically. We present a well-controlled, tunable artificial model to study chemotaxis and autochemotaxis in complex geometries, using microfluidic assays of self-propelling oil droplets in an aqueous surfactant solution...
December 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29243659/comparative-study-of-the-serum-measurement-of-pth-on-roche-cobas-e411%C3%A2-versus-the-abbott-architect-ci8200%C3%A2
#5
Mohammed Bensalah, Ouardia Bouayadi, Nawal Rahmani, Amina Lyagoubi, Somiya Lamrabat, Mohammed Choukri
Parathormone (PTH) is the main hormone of phosphocalcic homeostasis. It is synthesized and secreted by the parathyroid glands. PTH has become a routine test in the medical biology laboratory. However, its measurement presents analytical difficulties with the various marketed kits. The aim of this work is to present the results of a comparative study between the PTH measurment on Abbott architect ci8200 and on Roche's Cobas e411 automaton. It is a prospective study carried out for 252 hospitalized patients in the various departments of the University Hospital Center Mohammed VI of Oujda...
December 15, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29243416/partial-correlation-based-functional-connectivity-analysis-for-functional-near-infrared-spectroscopy-signals
#6
Ata Akın
A theoretical framework, a partial correlation-based functional connectivity (PC-FC) analysis to functional near-infrared spectroscopy (fNIRS) data, is proposed. This is based on generating a common background signal from a high passed version of fNIRS data averaged over all channels as the regressor in computing the PC between pairs of channels. This approach has been employed to real data collected during a Stroop task. The results show a strong significance in the global efficiency (GE) metric computed by the PC-FC analysis for neutral, congruent, and incongruent stimuli (NS, CS, IcS; GEN=0...
December 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29243212/controlling-centriole-numbers-geminin-family-members-as-master-regulators-of-centriole-amplification-and-multiciliogenesis
#7
REVIEW
Marina Arbi, Dafni-Eleftheria Pefani, Stavros Taraviras, Zoi Lygerou
To ensure that the genetic material is accurately passed down to daughter cells during mitosis, dividing cells must duplicate their chromosomes and centrosomes once and only once per cell cycle. The same key steps-licensing, duplication, and segregation-control both the chromosome and the centrosome cycle, which must occur in concert to safeguard genome integrity. Aberrations in genome content or centrosome numbers lead to genomic instability and are linked to tumorigenesis. Such aberrations, however, can also be part of the normal life cycle of specific cell types...
December 14, 2017: Chromosoma
https://www.readbyqxmd.com/read/29243038/what-performance-analysts-need-to-know-about-research-trends-in-association-football-2012-2016-a-systematic-review
#8
REVIEW
Hugo Sarmento, Filipe Manuel Clemente, Duarte Araújo, Keith Davids, Allistair McRobert, António Figueiredo
BACKGROUND: Evolving patterns of match analysis research need to be systematically reviewed regularly since this area of work is burgeoning rapidly and studies can offer new insights to performance analysts if theoretically and coherently organized. OBJECTIVE: The purpose of this paper was to conduct a systematic review of published articles on match analysis in adult male football, identify and organize common research topics, and synthesize the emerging patterns of work between 2012 and 2016, according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines...
December 14, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29242772/fungal-nomenclature-evolving-changes-adopted-by-the-19th-international-botanical-congress-in-shenzhen-2017-and-procedures-for-the-fungal-nomenclature-session-at-the-11th-international-mycological-congress-in-puerto-rico-2018
#9
David L Hawksworth, Tom W May, Scott A Redhead
This article summarizes the key changes in the rules relating to the nomenclature of fungi made at the XIX International Botanical Congress in Shenzhen, China, in July 2017. Most significant was the decision to transfer decision-making on matters related only to the naming of fungi from International Botanical to International Mycological Congresses (IMCs). The rules relating to fungi are to be grouped together in a separate section of the International Code of Nomenclature for algae, fungi, and plants (ICN)...
December 2017: IMA Fungus
https://www.readbyqxmd.com/read/29242014/anti-ige-treatment-with-oral-immunotherapy-in-multifood-allergic-participants-a-double-blind-randomised-controlled-trial
#10
Sandra Andorf, Natasha Purington, Whitney M Block, Andrew J Long, Dana Tupa, Erica Brittain, Amanda Rudman Spergel, Manisha Desai, Stephen J Galli, Kari C Nadeau, R Sharon Chinthrajah
BACKGROUND: Despite progress in single food oral immunotherapy, there is little evidence concerning the safety and efficacy of treating individuals with multiple food (multifood) allergies. We did a pilot study testing whether anti-IgE (omalizumab) combined with multifood oral immunotherapy benefited multifood allergic patients. METHODS: We did a blinded, phase 2 clinical trial at Stanford University. We enrolled participants, aged 4-15 years, with multifood allergies validated by double-blind, placebo-controlled food challenges to their offending foods...
December 11, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29241737/derivatization-of-honokiol-by-integrated-acetylation-and-methylation-for-improved-cutaneous-delivery-and-anti-inflammatory-potency
#11
Jia-You Fang, Tse-Hung Huang, Chi-Feng Hung, Yu-Ling Huang, Ibrahim A Aljuffali, Wei-Chun Liao, Chwan-Fwu Lin
A set of honokiol derivatives was synthesized to evaluate skin permeation and bioactivity. The reaction for derivatization included acetylation and methylation. The anti-inflammatory activity against neutrophils and macrophages was examined. The experimental setup for the assessment of cutaneous absorption was the in vitro Franz diffusion assembly. Honokiol and its derivatives significantly downregulated superoxide anion and elastase production in neutrophils, with honokiol showing the greatest inhibition. All derivatives could be completely hydrolyzed to the parent compounds after passing into the skin...
December 11, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29241473/-chris-arie-and-piet-three-politically-active-dutch-physicians-in-the-20th-century
#12
J G J Huurman
Chris Mol, Arie Querido and Piet Muntendam were three socially and politically active medical doctors in the 20th century. Inspired by different sources (Catholicism, and the social democratic and progressive-liberal movements), these doctors strove to improve public health in the Netherlands. Up to about 1940 they were primarily traditional doctors caring for individual patients. After World War Two their scope widened, eventually to the wider society. The life histories of the three main characters are remarkably intertwined...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29240455/development-and-evaluation-of-a-student-initiated-test-preparation-program-for-the-usmle-step-1-examination
#13
Lindsay F Schwartz, Matthew Lineberry, Yoon Soo Park, Carol S Kamin, Abbas A Hyderi
PROBLEM: Studies have documented performance on the United States Medical Licensing Examination® (USMLE) Step 1 exam as an important factor that residency program directors consider when deciding which applicants to interview and rank. Therefore, success on this exam, though only one aspect of applicant evaluation, is important in determining future career prospects for medical students. Unfortunately, mean test scores at the University of Illinois College of Medicine at Chicago (UIC) have historically been below the national average...
December 14, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/29240195/sub-rayleigh-resolution-ghost-imaging-by-spatial-low-pass-filtering
#14
Xi-Hao Chen, Fan-Hui Kong, Qiang Fu, Shao-Ying Meng, Ling-An Wu
A sub-Rayleigh resolution ghost imaging experiment is performed via post-detection spatial low-pass filtering of the instantaneous intensity. A super-resolution reconstructed image has been achieved, in which the spatial resolution can exceed the Rayleigh diffraction limit by more than a factor of two. The resolution depends on the filter threshold, and the Rayleigh limit can be exceeded for a wide choice of threshold values. The setup is simple and easy to implement, which is an advantage for practical applications...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29240108/wavelength-measurement-by-fourier-analysis-of-interference-fringes-through-a-plane-parallel-plate
#15
Choonghwan Lee, Heejoo Choi, Jiung Kim, Myoungsik Cha, Jonghan Jin
When a diverging laser beam passed through a plane parallel glass plate, interference fringes were observed; analysis of these fringes provided accurate estimation of the source wavelength. The fringes had a unique angular range of uniform fringe density. Fourier transform of the fringes in this range directly provided wavelength information. Reference lasers were used to establish a calibration between the fringe density and wavenumber, with which we estimated the wavelength of a test laser. An accuracy of 4...
December 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29239856/bioinspired-nanoparticle-spray-coating-for-superhydrophobic-flexible-materials-with-oil-water-separation-capabilities
#16
Nicasio R Geraldi, Linzi E Dodd, Ben Xu, David Wood, Gary Wells, Glen McHale, Michael I Newton
Much of the inspiration for the creation of superhydrophobic surfaces has come from nature, from plant such as the Sacred Lotus (Nulembo nucifera), where the micro-scale papillae epidermal cells on the surfaces of the leaves are covered with nano-scale epicuticular wax crystalloids. The combination of the surface roughness and the hydrophobic wax coating produces a superhydrophobic wetting state on the leaves allowing them to self-clean and easily shed water. Here a simple scale-up carbon nanoparticle spray coating is presented that mimics the surface of the Sacred Lotus leaves and can be applied to a wide variety of materials, complex structures, and flexible substrates, rendering them superhydrophobic, with contact angles above 160°...
December 14, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/29239841/totally-intra-corporeal-pringle-maneuver-during-laparoscopic-liver-resection
#17
Andrea Laurenzi, Daniel Cherqui, Rodrigo Figueroa, René Adam, Eric Vibert, Antonio Sa Cunha
INTRODUCTION: Laparoscopic resection has gained a significant place in liver surgery. As in open liver resection, bleeding control during hepatic transection remains a major issue and it represents the main reason for conversion to laparotomy. Pringle maneuver (PM) remains the standard inflow occlusion technique and a specific step-by-step description of totally intracorporeal laparoscopic PM is described. METHODS: The technique includes placement of a tape around the hepatoduodenal which is then passed through a plastic drain...
November 24, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29239735/burns-centre-and-fire-services-what-information-can-be-exchanged-to-manage-the-burn-patient
#18
O Pujji, B Nizar, J Bechar, D North, S Jeffery
AIM: To describe the experience of using a "Burns Extrication Form" at a regional Burns Centre. Communication between the fire services and burns team previously has been regarded as poor. Significant information is collected by the fire services at the scene and this can aid the management of the patient. METHODS: The Burns Extrication Form was devised to provide a clear framework of communication between the two services. Information regarding time frames, exposure to heat & smoke, fire loading (potential severity of a fire in a given space by measuring amount of combustible material in confined space), building construction, chemicals involved is passed to the medical team through this form through a National Health Service mailbox...
November 24, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29239410/uptake-and-transcytosis-of-functionalized-superparamagnetic-iron-oxide-nanoparticles-in-an-in-vitro-blood-brain-barrier-model
#19
Angela Ivask, Emily H Pilkington, Thomas Blin, Aleksandr Käkinen, Heiki Vija, Meeri Visnapuu, John F Quinn, Michael R Whittaker, Ruirui Qiao, Thomas P Davis, Pu Chun Ke, Nicolas H Voelcker
Two major hurdles in nanomedicine are the limited strategies for synthesizing stealth nanoparticles and the poor efficacy of the nanoparticles in translocating across the blood brain barrier (BBB). Here we examined the uptake and transcytosis of iron oxide nanoparticles (IONPs) grafted with biomimetic phosphorylcholine (PC) brushes in an in vitro BBB model system, and compared them with bare, PEG or PC-PEG mixture grafted IONPs. Hyperspectral imaging indicated IONP co-localization with cells. Quantitative analysis with total reflection X-ray fluorescence spectrometry showed that after 24 h, 78% of PC grafted, 68-69% of PEG or PC-PEG grafted, and 30% of bare IONPs were taken up by the BBB...
December 14, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29239250/history-off-hand-bunnell-s-no-man-s-land
#20
J Joris Hage
BACKGROUND: To date, it remains unclear what inspired Dr Sterling Bunnell to start using the typical World War I military term no-man's land in hand surgical context, only in 1948. To commemorate that Bunnell passed away 60 years ago on August 20, I report on my quest to clarify this. METHODS: An extensive bibliography of Bunnell was made up by use of the McDowell Series of Plastic Surgery Indexes and cross-checked by use of a PubMed search. Bunnell's round-robin letters were searched for in the Sterling Bunnell Hand Surgery Archives of the California Pacific Medical Center Health Services Library in San Francisco, California...
December 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
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