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https://www.readbyqxmd.com/read/28445557/us-adult-illicit-cannabis-use-cannabis-use-disorder-and-medical-marijuana-laws-1991-1992-to-2012-2013
#1
Deborah S Hasin, Aaron L Sarvet, Magdalena Cerdá, Katherine M Keyes, Malka Stohl, Sandro Galea, Melanie M Wall
Importance: Over the last 25 years, illicit cannabis use and cannabis use disorders have increased among US adults, and 28 states have passed medical marijuana laws (MML). Little is known about MML and adult illicit cannabis use or cannabis use disorders considered over time. Objective: To present national data on state MML and degree of change in the prevalence of cannabis use and disorders. Design, Participants, and Setting: Differences in the degree of change between those living in MML states and other states were examined using 3 cross-sectional US adult surveys: the National Longitudinal Alcohol Epidemiologic Survey (NLAES; 1991-1992), the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; 2001-2002), and the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III; 2012-2013)...
April 26, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28445489/video-quality-assessment-using-motion-compensated-temporal-filtering-and-manifold-feature-similarity
#2
Yang Song, Mei Yu, Gangyi Jiang, Feng Shao, Zongju Peng
Well-performed Video quality assessment (VQA) method should be consistent with human visual systems for better prediction accuracy. In this paper, we propose a VQA method using motion-compensated temporal filtering (MCTF) and manifold feature similarity. To be more specific, a group of frames (GoF) is first decomposed into a temporal high-pass component (HPC) and a temporal low-pass component (LPC) by MCTF. Following this, manifold feature learning (MFL) and phase congruency (PC) are used to predict the quality of temporal LPC and temporal HPC respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28445263/acupuncture-for-enhancing-early-recovery-of-bowel-function-in-cancer-protocol-for-a-systematic-review
#3
Yi-Hua Liu, Yang Ye, Jia-Bin Zheng, Xue-Qian Wang, Ying Zhang, Hong-Sheng Lin
BACKGROUND: Cancer patients undergoing surgical procedure often suffer from bowel dysfunction and postoperative ileus (POI). Cancer management for early recovery of bowel function is still a challenging topic. Acupuncture has been commonly used in a variety of gastrointestinal diseases. The aim of this study is to evaluate the effects of acupuncture therapy to reduce the duration of POI and enhance bowel function in cancer patients. METHODS: We will systematically screen all randomized controlled trials (RCTs) published through electronically and hand searching...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444965/serum-free-light-chain-quantitative-assays-dilemma-of-a-biomarker
#4
Giovanni Cigliana, Francesca Gulli, Cecilia Napodano, Krizia Pocino, Elena De Santis, Luigi Colacicco, Iole Cordone, Laura Conti, Umberto Basile
BACKGROUND: Serum free light chains detection assays are consistently meeting greater interest for the diagnosis and monitoring of monoclonal gammopathies and plasma cell dyscrasias. Nowadays, there are neither standardized methods nor reference material for the determination of free light chains; for this reason, it is important to compare two different assays used in clinical laboratory. METHODS: We evaluated 300 serum samples from patients with B-cell disorders and compared the analytical performances of both assay...
April 26, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28444939/continuous-ambulatory-peritoneal-dialysis-ascitic-and-pleural-body-fluids-evaluation-with-the-mindray-bc-6800-hematology-analyzer
#5
Oscar Fuster, Belinda Andino, Amparo Pardo, Begoña Laiz
BACKGROUND: Accurate evaluation of hematology analyzers is recommended before these devices can be broadly introduced for the routine testing of continuous ambulatory peritoneal dialysis (CAPD), ascitic, and pleural fluids. METHODS: We evaluated the performance of Mindray BC-6800 for white blood cell (WBC) and differential cell count in 50 CAPD, 60 ascitic and 40 pleural compared with manual microscopy. Within-run precision, limit of blank (LoB), limit of detection (LoD), limit of quantitation (LoQ), and carryover were assessed...
April 26, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28444772/multi-atlas-approach-with-local-registration-goodness-weighting-for-mri-based-electron-density-mapping-of-head-and-neck-anatomy
#6
Reza Farjam, Neelam Tyagi, Harini Veeraraghavan, Aditya Apte, Kristen Zakian, Margie A Hunt, Joseph O Deasy
PURPOSE: The growing use of magnetic resonance imaging (MRI) as a substitute for computed tomography-based treatment planning requires the development of effective algorithms to generate electron density maps for treatment planning and patient setup verification. The purpose of this work was to develop a method to synthesize computerized tomography (CT) for MR-only radiotherapy of head and neck cancer patients. METHODS: The algorithm is based on registration of multiple patient datasets containing both MRI and CT images (a "multi-atlas" algorithm)...
April 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28444650/-newborn-screening-on-cystic-fibrosis-in-germany-comparison-of-the-new-screening-protocol-with-an-alternative-protocol
#7
Olaf Sommerburg, Mirjam Stahl, Jutta Hammermann, Jürgen G Okun, Andreas Kulozik, Georg Hoffmann, Marcus Mall
Background For the new cystic fibrosis (CF) newborn screening program in Germany the Federal Joint Committee (G-BA) implemented a new screening protocol using immunoreactive trypsinogen (IRT) as first and pancreatitis associated protein (PAP) as second tier. Gene analysis with a panel of 31 CFTR-mutations is used as third tier to increase the positive predictive value (PPV) which is known to be low in pure biochemical IRT/PAP protocols. Methods For post hoc analysis the data pool (n=372 906) of a study evaluating a pure biochemical IRT/PAP protocol was used for assessment of the 3-step G-BA protocol in comparison with an alternative screening protocol recommended by the authors...
March 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28444594/bio-transformation-and-stabilization-of-arsenic-as-in-contaminated-soil-using-arsenic-oxidizing-bacteria-and-fecl3-amendment
#8
Santosh Kumar Karn, Xiangliang Pan, Ian R Jenkinson
A combination of biological and chemical methods was applied in the present study to evaluate the removal of arsenic (As) from contaminated soil. The treatment involved As-oxidizing microbes aimed of transforming the more toxic As (III) to less toxic As (V) in the soil. FeCl3 was added at three different concentrations (1, 2, and 3%) to stabilize the As (V). Leaching of the treated soil was investigated by making a soil column and passing tap water through it to determine solubility. Experimental results indicated that the bacterial activity had a pronounced positive effect on the transformation of As, and decreased the soluble exchangeable fraction from 50 to 0...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28443571/numerical-optimization-of-the-position-in-femoral-head-of-proximal-locking-screws-of-proximal-femoral-nail-system-biomechanical-study
#9
Mehmet Nuri Konya, Özgür Verim
BACKGROUND: Proximal femoral fracture rates are increasing due to osteoporosis and traffic accident. Proximal femoral nails are routinely used in the treatment of these fractures on the proximal femur. AIMS: The present study aimed to compare various combination and to determine ideal proximal lag screw (PLS) position on the pertrochanteric fractures (AO classification 31-A1) of femur by using optimised finite element analysis. STUDY DESIGN: Biomechanical Study...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28443390/an-integrative-index-for-predicting-extubation-outcomes-after-successful-completion-of-a-spontaneous-breathing-trial-in-an-adult-medical-intensive-care-unit
#10
Tsung-Ju Wu, Judith Shu-Chu Shiao, Hsin-Liang Yu, Ruay-Sheng Lai
BACKGROUND: Among respiratory predictors, rapid shallow breathing index (RSBI) has been a commonly used respiratory parameter to predict extubation outcomes. However, the outcome of prediction remains inconsistent. Regarding nonrespiratory predictors, serum albumin, hemoglobin, bicarbonate, and patients' alertness have been reported to be associated with successful weaning or extubation. We aimed to develop an integrative index combining commonly used predictors in the adult medical intensive care units (MICUs) and to compare the predictability of the index with RSBI...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28443296/data-of-sperm-entry-inability-in-drosophila-melanogaster-ovarian-follicles-that-are-depleted-of-s36-chorionic-protein
#11
Athanassios D Velentzas, Panagiotis D Velentzas, Stamatia Katarachia, Vassiliki E Mpakou, Issidora S Papassideri, Dimitrios J Stravopodis
This paper presents data associated with the research article entitled "Targeted downregulation of s36 protein unearths its cardinal role in chorion biogenesis and architecture during Drosophila melanogaster oogenesis" [1]. Drosophila chorion is produced by epithelial follicle cells and one of its functional serving role is egg fertilization through the micropyle, a specialized narrow channel at the anterior tip of the egg [2]. Sperm entry during fertilization is necessary for the egg to complete meiosis [3]...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28443188/intestinal-obstruction-induced-by-peach-stone-in-stenosis-of-sigmoid-colon-by-adenocarcinoma-a-case-report-and-literature-review
#12
Argos Soares de Matos Filho, Clarissa Santos Neto, Andreia Souto da Motta, Isabela de Alencar E Lombardi, Ronielly Araújo Rocha
INTRODUCTION: Intestinal obstruction is the second among the most frequent acute abdominal conditions of the non-traumatic surgical pathologies. It is Found in 20% of patients admitted to the emergency care services with acute abdominal pain. It often results in high morbidity and mortality. PRESENTATION OF CASE: We report a case of a foreign body resulting in a colon obstruction, concomitant with the diagnosis of a sigmoid cancer in a 47-year-old female. DISCUSSION: There are only a few cases of Intestinal Obstruction Induced by Peach Stone in Stenosis of Sigmoid Colon by Adenocarcinoma reported in the world literature...
May 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28442663/histochemical-assessment-for-osteoblastic-activity-coupled-with-dysfunctional-osteoclasts-in-c-src-deficient-mice
#13
Hisashi Toray, Tomoka Hasegawa, Naoko Sakagami, Erika Tsuchiya, Ai Kudo, Shen Zhao, Yasuhito Moritani, Miki Abe, Taiji Yoshida, Tomomaya Yamamoto, Tsuneyuki Yamamoto, Kimimitsu Oda, Nobuyuki Udagawa, Paulo Henrique Luiz de Freitas, Minqi Li
Since osteoblastic activities are believed to be coupled with osteoclasts, we have attempted to histologically verify which of the distinct cellular circumstances, the presence of osteoclasts themselves or bone resorption by osteoclasts, is essential for coupled osteoblastic activity, by examining c-fos(-/-) or c-src(-/-) mice. Osteopetrotic c-fos deficient (c-fos(-/-)) mice have no osteoclasts, while c-src deficient (c-src(-/-)) mice, another osteopetrotic model, develop dysfunctional osteoclasts due to a lack of ruffled borders...
2017: Biomedical Research
https://www.readbyqxmd.com/read/28442244/automatic-high-resolution-infarct-detection-using-volumetric-multiphase-dual-energy-ct
#14
Veit Sandfort, Alan C Kwan, Comfort Elumogo, Davis M Vigneault, Rolf Symons, Amir Pourmorteza, Kelly Rice, Cynthia Davies-Venn, Mark A Ahlman, Chia-Ying Liu, Stefan L Zimmerman, David A Bluemke
OBJECTIVES: Late contrast enhancement CT (LCE-CT) visualizes the presence of myocardial infarcts. Differentiation of the contrast-enhanced infarct from blood pool is challenging. We developed a novel method using data from first pass CT angiography (CTA) imaging to enable automatic infarct detection. MATERIALS AND METHODS: A canine model of myocardial infarction was produced in 11 animals. Two months later, first pass CTA (90 kVp) and LCE-CT (dual energy 90 kVp/150 kVp tin filtered) were performed...
April 18, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28442183/assessment-of-competence-in-evar-stent-graft-sizing-and-selection
#15
M Strøm, L Lönn, B Bech, T V Schroeder, L Konge
OBJECTIVES AND BACKGROUND: The aims of this study were to develop a test of competence in endovascular aortic repair (EVAR) stent graft sizing and selection; to examine the test for evidence of validity; and to explore the experience required for the task. METHODS: The test was developed based on a literature review resulting in 22 anatomical assessment points and a graft selection. Validity evidence was explored in an international cross sectional study. Twenty-two consultants with varying levels of experience in the field (novices, intermediates, and experts) were presented with computed tomography angiography of the aortic vessels from three patients...
April 22, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28441870/protein-nanocellulose-interactions-in-paper-filters-for-advanced-separation-applications
#16
Simon Johan Gustafsson, Levon Manukyan, Albert Mihranyan
Protein-based pharmaceutics are widely explored for healthcare applications, and six out of ten best selling drugs today are biologicals. The goal of this work was to evaluate the protein nanocellulose interactions in paper filter for advanced separation applications such as virus removal filtration and bioprocessing. The protein recovery was measured for bovine serum albumin (BSA), γ-Globulin and Lysozyme using biuret total protein reagent and polyacrylamide gel electrophoresis (SDS-PAGE), and the throughput was characterized in terms of flux values from fixed volume filtrations at various protein concentrations and under worst-case experimental conditions...
April 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28441271/alternative-payment-models-and-urology
#17
Deborah R Kaye, David C Miller, Chad Ellimoottil
PURPOSE OF REVIEW: The Medicare Access and CHIP Reauthorization Act (MACRA) is a historic bill that was recently passed that establishes how quality measurement and practice patterns will affect physician reimbursement. Alternative payment models (APMs) are an essential component of MACRA and Medicare's vision of paying for high-value care. This review describes APMs in the context of MACRA and their impact on urology. RECENT FINDINGS: The majority of urologists will be affected by MACRA...
April 22, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28440949/regulations-and-policies-regarding-e-cigarettes
#18
REVIEW
Leila F Barraza, Kim E Weidenaar, Livia T Cook, Andrea R Logue, Michael T Halpern
Electronic cigarettes (e-cigarettes) are a growing public health concern because of a dramatic increase in use by adolescents and the uncertainty of potential health impacts. These health concerns and lack of an established federal regulatory scheme have led many local and state governments to address the regulatory void for e-cigarettes by incorporating them into the statutory definition of tobacco or by passing laws specific to the use of e-cigarettes. In August 2016, the US Food and Drug Administration issued a final rule deeming e-cigarettes within their authority; providing uniform requirements like premarket approval applications, Harmful and Potentially Harmful Constituents reporting, and warning labels; and establishing 18 years as a minimum age of purchase...
April 25, 2017: Cancer
https://www.readbyqxmd.com/read/28440941/ingestion-of-microplastics-by-fish-and-its-potential-consequences-from-a-physical-perspective
#19
Boris Jovanović
The European Marine Strategy Framework Directive and the United States Microbead Free Waters Act are credited for being ambitious in their goals for protecting the marine environment from microplastics pollution. As a result, the microplastic pollution of marine environments and the incidence of microplastic ingestion by fish is rapidly receiving an increase in overdue attention. This commentary summarizes recent discoveries regarding the potential negative effects of micro- and nanoplastic ingestion by fish...
May 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28440838/detection-and-sizing-of-nanoparticles-and-dna-on-pdms-nanofluidic-chips-based-on-differential-resistive-pulse-sensing
#20
Ran Peng, Dongqing Li
The RPS (Resistive Pulse Sensing) technique is a popular tool for the label-free detection of particles. This paper describes a simple, cost-effective PDMS nanofluidic chip for the detection and characterization of nanoparticles based on the differential RPS technique with high resolution and sensitivity. The chip is composed of two layers of PDMS slabs. Microchannel systems fabricated by the photolithography method on the top layer are used for sample loading and differential signal acquisition, and a straight nanochannel on the bottom layer fabricated by an unconventional approach bridging the gap between the microchannels works as an RPS sensing gate...
April 25, 2017: Nanoscale
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