keyword
MENU ▼
Read by QxMD icon Read
search

order set or order sets or carepath or care path

keyword
https://www.readbyqxmd.com/read/27904174/on-the-history-of-classification-in-dermatology
#1
Amiya Kumar Mukhopadhyay
Since the early days of cutaneous medicine, naming of the entities had remained a confusing subject. Earlier texts of all ancient civilisations are almost similar in this topic The Biblical controversy regarding the actual translational meaning of the original Hebrew term Zara 'at has become a centre of controversy amongst many research scholars of the medical history. Similar debate exists about the Ayurvedic term Kustha---- whether it meant leprosy or stood for a number of skin affliction is a matter of controversy...
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27903444/design-of-an-elastin-layered-dermal-regeneration-template
#2
Suzanne M Mithieux, Anthony S Weiss
: We demonstrate a novel approach for the production of tunable quantities of elastic fibers. We also show that exogenous tropoelastin is rate-limiting for elastin synthesis regardless of the age of the dermal fibroblast donor. Additionally, we provide a strategy to further enhance synthesis by older cells through the application of conditioned media. We show that this approach delivers an elastin layer on one side of the leading dermal repair template for contact with the deep dermis in order to deliver prefabricated elastic fibers to a physiologically appropriate site during subsequent surgery...
November 26, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27901290/early-life-trauma-post-traumatic-stress-disorder-and-allostatic-load-in-a-sample-of-american-indian-adults
#3
Zaneta Thayer, Celestina Barbosa-Leiker, Michael McDonell, Lonnie Nelson, Dedra Buchwald, Spero Manson
OBJECTIVES: Among American Indians, prior research has found associations between early life trauma and the development of post-traumatic stress disorder (PTSD) in adulthood. Given the physiological changes associated with PTSD, early life trauma could indirectly contribute to chronic disease risk. However, the impact of early life trauma on adult physical health in this population has not been previously investigated. METHODS: We evaluated associations among early life trauma, PTSD, and 13 physiological biomarkers that index cardiovascular, metabolic, neuroendocrine, anthropometric, and immune function in adulthood by conducting correlation and structural equation modeling path analyses (N = 197)...
November 30, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27900526/the-prospective-associations-between-self-efficacy-and-depressive-symptoms-from-early-to-middle-adolescence-a-cross-lagged-model
#4
Yuli R Tak, Steven M Brunwasser, Anna Lichtwarck-Aschoff, Rutger C M E Engels
Over the course of adolescence, an increasing number of adolescents experience depression. In order to effectively target depression, identifying risk factors for depressive symptoms is pivotal. Since low levels of self-efficacy were associated with higher levels of depressive symptoms in previous studies, the current study investigated the bidirectional and prospective associations between depressive symptoms and academic, social and emotional self-efficacy from early to mid adolescence in a cross-lagged path model...
November 29, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27897399/density-functional-theory-research-on-the-reduction-mechanism-for-the-solvent-additive-in-sodium-ion-battery
#5
Qi Liu, Daobin Mu, Borong Wu, Lei Wang, Liang Gai, Feng Wu
Solid electrolyte interface (SEI) film in Na-ion battery is closely related to capacity fading and cycling stability of the battery. However, there is less study on SEI film of Na-ion battery and the mechanism of SEI film formation is unclear. The mechanism for the reduction of ethylene carbonate (EC), propylene carbonate (PC), vinylene carbonate (VC), ethylene sulfite (ES), 1,3-propylene sulfite (PS) and fluorinated ethylene carbonate (FEC) is studied by density functional theory (DFT) method. The reaction activation energy, Gibbs free energies and enthalpies, structures of the transition states etc...
November 29, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27896968/exploring-the-reproducibility-of-probabilistic-causal-molecular-network-models
#6
Ariella Cohain, Aparna A Divaraniya, Kuixi Zhu, Joseph R Scarpa, Andrew Kasarskis, Jun Zhu, Rui Chang, Joel T Dudley, Eric E Schadt
Network reconstruction algorithms are increasingly being employed in biomedical and life sciences research to integrate large-scale, high-dimensional data informing on living systems. One particular class of probabilistic causal networks being applied to model the complexity and causal structure of biological data is Bayesian networks (BNs). BNs provide an elegant mathematical framework for not only inferring causal relationships among many different molecular and higher order phenotypes, but also for incorporating highly diverse priors that provide an efficient path for incorporating existing knowledge...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27896347/first-principles-study-of-pressure-induced-structural-phase-transitions-in-mnf2
#7
S López-Moreno, A H Romero, J Mejía-López, A Muñoz
In this work we report a complete structural and magnetic characterization of crystalline MnF2 under pressure obtained using first principle calculations. Density functional theory was used as the theoretical framework, within the generalized gradient approximation plus the Hubbard formalism (GGA+U) necessary to describe the strong correlations present in this material. The vibrational, the magnetic exchange couplings and the structural characterization of MnF2 in the rutile ground state structure and potential high pressure phases are reported...
November 29, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27893757/assessing-the-acetabular-cup-implant-primary-stability-by-impact-analyses-a-cadaveric-study
#8
Adrien Michel, Romain Bosc, Jean-Paul Meningaud, Philippe Hernigou, Guillaume Haiat
BACKGROUND: The primary stability of the acetabular cup (AC) implant is an important determinant for the long term success of cementless hip surgery. However, it remains difficult to assess the AC implant stability due to the complex nature of the bone-implant interface. A compromise should be found when inserting the AC implant in order to obtain a sufficient implant stability without risking bone fracture. The aim of this study is to evaluate the potential of impact signals analyses to assess the primary stability of AC implants inserted in cadaveric specimens...
2016: PloS One
https://www.readbyqxmd.com/read/27892914/the-effects-of-transformational-leadership-and-mediating-factors-on-the-organizational-success-using-structural-equation-modeling-a-case-study
#9
Ramin Ravangard, Sakine Karimi, Payam Farhadi, Zahra Sajjadnia, Nasrin Shokrpour
This study was undertaken to determine the effects of transformational leadership (TL) and mediating factors on organizational success (OS) from the administrative, financial, and support employees' perspective in teaching hospitals affiliated with Shiraz University of Medical Sciences using structural equation modeling. Three hundred administrative and financial employees were selected, using stratified sampling proportional to size and simple random sampling. Data were collected using 5 questionnaires and analyzed using SPSS 21...
January 2016: Health Care Manager
https://www.readbyqxmd.com/read/27890532/what-governs-successful-performance-of-a-complex-whole-body-movement-the-kovacs-release-regrasp-on-horizontal-bar
#10
Michael J Hiley, Maurice R Yeadon
The Kovacs is a release and regrasp skill performed on the horizontal bar in men׳s artistic gymnastics. It is a popular skill in elite competitive gymnastics with over 40% of male gymnasts performing a variation of the Kovacs at the London 2012 Olympics. In the qualifying competition 84% of Kovacs were successfully regrasped, with the remaining 16% resulting in a fall. The aim of the present study was to determine why some gymnasts are more successful than others at regrasping the bar, with a secondary aim to determine how a less successful gymnast could alter his technique in order to become more successful...
November 16, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27881953/connectomic-analysis-of-brain-networks-novel-techniques-and-future-directions
#11
REVIEW
J Leonie Cazemier, Francisco Clascá, Paul H E Tiesinga
Brain networks, localized or brain-wide, exist only at the cellular level, i.e., between specific pre- and post-synaptic neurons, which are connected through functionally diverse synapses located at specific points of their cell membranes. "Connectomics" is the emerging subfield of neuroanatomy explicitly aimed at elucidating the wiring of brain networks with cellular resolution and a quantified accuracy. Such data are indispensable for realistic modeling of brain circuitry and function. A connectomic analysis, therefore, needs to identify and measure the soma, dendrites, axonal path, and branching patterns together with the synapses and gap junctions of the neurons involved in any given brain circuit or network...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27878643/the-evolution-of-drug-design-at-merck-research-laboratories
#12
Frank K Brown, Edward C Sherer, Scott A Johnson, M Katharine Holloway, Bradley S Sherborne
On October 5, 1981, Fortune magazine published a cover article entitled the "Next Industrial Revolution: Designing Drugs by Computer at Merck". With a 40+ year investment, we have been in the drug design business longer than most. During its history, the Merck drug design group has had several names, but it has always been in the "design" business, with the ultimate goal to provide an actionable hypothesis that could be tested experimentally. Often the result was a small molecule but it could just as easily be a peptide, biologic, predictive model, reaction, process, etc...
November 23, 2016: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/27878166/mechanism-of-excited-state-deactivation-of-indan-1-ylidene-and-fluoren-9-ylidene-malononitriles
#13
Leandro A Estrada, Antonio Francés-Monerris, Igor Schapiro, Massimo Olivucci, Daniel Roca-Sanjuán
Herein, we report complementary computational and experimental evidence supporting the existence, for indan-1-ylidene malononitrile and fluoren-9-ylidene malononitrile, of a non-radiative decay channel involving double bond isomerisation motion. The results of UV-Vis transient absorption spectroscopy highlight that the decay takes place within hundreds of picoseconds. In order to understand the related molecular mechanism, photochemical reaction paths were computed by employing multiconfigurational quantum chemistry...
November 23, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27877874/growth-condition-dependence-of-unintentional-oxygen-incorporation-in-epitaxial-gan
#14
Felix Schubert, Steffen Wirth, Friederike Zimmermann, Johannes Heitmann, Thomas Mikolajick, Stefan Schmult
Growth conditions have a tremendous impact on the unintentional background impurity concentration in gallium nitride (GaN) synthesized by molecular beam epitaxy and its resulting chemical and physical properties. In particular for oxygen identified as the dominant background impurity we demonstrate that under optimized growth stoichiometry the growth temperature is the key parameter to control its incorporation and that an increase by 55 °C leads to an oxygen reduction by one order of magnitude. Quantitatively this reduction and the resulting optical and electrical properties are analyzed by secondary ion mass spectroscopy, photoluminescence, capacitance versus voltage measurements, low temperature magneto-transport and parasitic current paths in lateral transistor test structures based on two-dimensional electron gases...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27877042/effects-of-carbopol-%C3%A2-934-proportion-on-nanoemulsion-gel-for-topical-and-transdermal-drug-delivery-a-skin-permeation-study
#15
Yin Zheng, Wu-Qing Ouyang, Yun-Peng Wei, Shahid Faraz Syed, Chao-Shuang Hao, Bo-Zhen Wang, Yan-Hong Shang
Nanoemulsions (NEs) are used as transdermal drug delivery systems for systematic therapeutic purposes. We hypothesized that the skin permeation profile of an NE could be modulated by incorporating it into a hydrogel containing differing proportions of thickening agent. The objectives of this study were as follows: 1) to determine the stability and skin irritability of NE gels (NGs) containing 1%, 2%, and 3% (w/w) Carbopol(®) 934 (CP934) (termed NG1, NG2, and NG3, respectively); 2) to compare the skin permeation profiles and drug deposition patterns of the NGs; and 3) to visualize the drug delivery routes of the NGs...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27874101/molecular-mechanism-of-carbon-nanotube-to-activate-subtilisin-carlsberg-in-polar-and-non-polar-organic-media
#16
Liyun Zhang, Yuzhi Li, Yuan Yuan, Yuanyuan Jiang, Yanzhi Guo, Menglong Li, Xuemei Pu
In the work, we mainly used molecular dynamics (MD) simulation and protein structure network (PSN) to study subtilisin Carlsberg (SC) immobilized onto carbon nanotube (CNT) in water, acetonitrile and heptane solvents, in order to explore activation mechanism of enzymes in non-aqueous media. The result indicates that the affinity of SC with CNT follows the decreasing order of water > acetonitrile > heptane. The overall structure of SC and the catalytic triad display strong robustness to the change of environments, responsible for the activity retaining...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27874019/long-range-synchrony-and-emergence-of-neural-reentry
#17
Hanna Keren, Shimon Marom
Neural synchronization across long distances is a functionally important phenomenon in health and disease. In order to access the basis of different modes of long-range synchrony, we monitor spiking activities over centimetre scale in cortical networks and show that the mode of synchrony depends upon a length scale, λ, which is the minimal path that activity should propagate through to find its point of origin ready for reactivation. When λ is larger than the physical dimension of the network, distant neuronal populations operate synchronously, giving rise to irregularly occurring network-wide events that last hundreds of milliseconds to several seconds...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27873092/molecular-high-order-harmonic-spectra-and-its-application-to-the-generation-of-the-isolated-attosecond-pulse
#18
Li-Qiang Feng, Hang Liu, Wenliang Li, Rich-Samuel Castle
Molecular high-order harmonic generation (HHG) spectra from H2(+) and its application to the generation of the isolated attosecond pulses (IAPs) have been numerically investigated. Results show that (i) the 7th harmonic order is enhanced with the nuclei around the equilibrium internuclear, and as the internuclear distance increased, this enhanced harmonic produces a red-shift (even disappearance). Theoretical analyses show that the electronic transition between the ground and the 1st excited states is responsible for the red-shift enhanced harmonic...
December 2016: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/27872299/the-emergence-of-longevous-populations
#19
Fernando Colchero, Roland Rau, Owen R Jones, Julia A Barthold, Dalia A Conde, Adam Lenart, Laszlo Nemeth, Alexander Scheuerlein, Jonas Schoeley, Catalina Torres, Virginia Zarulli, Jeanne Altmann, Diane K Brockman, Anne M Bronikowski, Linda M Fedigan, Anne E Pusey, Tara S Stoinski, Karen B Strier, Annette Baudisch, Susan C Alberts, James W Vaupel
The human lifespan has traversed a long evolutionary and historical path, from short-lived primate ancestors to contemporary Japan, Sweden, and other longevity frontrunners. Analyzing this trajectory is crucial for understanding biological and sociocultural processes that determine the span of life. Here we reveal a fundamental regularity. Two straight lines describe the joint rise of life expectancy and lifespan equality: one for primates and the second one over the full range of human experience from average lifespans as low as 2 y during mortality crises to more than 87 y for Japanese women today...
November 21, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27872280/graphene-oxide-based-efficient-and-scalable-solar-desalination-under-one-sun-with-a-confined-2d-water-path
#20
Xiuqiang Li, Weichao Xu, Mingyao Tang, Lin Zhou, Bin Zhu, Shining Zhu, Jia Zhu
Because it is able to produce desalinated water directly using solar energy with minimum carbon footprint, solar steam generation and desalination is considered one of the most important technologies to address the increasingly pressing global water scarcity. Despite tremendous progress in the past few years, efficient solar steam generation and desalination can only be achieved for rather limited water quantity with the assistance of concentrators and thermal insulation, not feasible for large-scale applications...
November 21, 2016: Proceedings of the National Academy of Sciences of the United States of America
keyword
keyword
112646
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"