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https://www.readbyqxmd.com/read/28727629/an-automated-inpatient-split-dose-bowel-preparation-system-improves-colonoscopy-quality-and-reduces-repeat-procedures
#1
Rena Yadlapati, Elyse R Johnston, Adam B Gluskin, Dyanna L Gregory, Rachel Cyrus, Lindsay Werth, Jody D Ciolino, David P Grande, Rajesh N Keswani
BACKGROUND/GOALS: Inpatient colonoscopy preparations are often inadequate, compromising patient safety and procedure quality, while resulting in greater hospital costs. The aims of this study were to: (1) design and implement an electronic inpatient split-dose bowel preparation order set; (2) assess the intervention's impact upon preparation adequacy, repeated colonoscopies, hospital days, and costs. STUDY: We conducted a single center prospective pragmatic quasiexperimental study of hospitalized adults undergoing colonoscopy...
July 19, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28727616/iterative-reconstruction-may-improve-diagnosis-of-gout-an-ex-vivo-bio-phantom-dual-energy-computed-tomography-study
#2
Torsten Diekhoff, Maximilian Kotlyarov, Jürgen Mews, Bernd Hamm, Kay-Geert Armin Hermann
OBJECTIVES: We hypothesize that, compared with filtered back projection (FBP), iterative reconstruction (IR) increases the detected volume of uric acid, which serves as a measure of the sensitivity of the method, and therefore allows examinations with lower radiation exposure. Thus, the aim of our study was to evaluate the role of IR in dual-energy computed tomography (DECT) for gout assessment and volumetry in an ex vivo gout model using an epoxy phantom and a biophantom. MATERIALS AND METHODS: We prepared specimens with different concentrations of monosodium uric acid in ultrasound gel (30%-50%) and inserted them into an epoxy-based phantom and a porcine foreleg...
July 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28727551/inverse-rendering-and-relighting-from-multiple-color-plus-depth-images
#3
Siying Liu, Minh N Do
We propose a novel relighting approach that takes advantage of multiple color plus depth images acquired from a consumer camera. Assuming distant illumination and Lambertian reflectance, we model the reflected light field in terms of spherical harmonic coefficients of the Bi-directional Reflectance Distribution Function (BRDF) and lighting. We make use of the noisy depth information together with color images taken under different illumination conditions to refine surface normals inferred from depth. We first perform refinement on the surface normals using the first order spherical harmonics...
July 18, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28727328/-how-to-use-microbiological-diagnostic-tests-in-a-hospital-setting
#4
Romain Martischang, Mohamed Abbas, Stephan Harbarth, Benedikt Huttner, Jacques Schrenzel
Microbiological cultures provide essential information to guide the antibiotic therapy. However, their results might be misleading for physicians and drive useless treatment, sometimes harmful for patients. Recommendations highlight the importance of clinical signs in order to take into account the pre-test probability when interpreting the results. This combination will improve the predictive value of microbiological tests. The sampling strategy is also important to avoid an overuse of these tests but also misleading results through a reduction of contaminants...
April 12, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28726971/an-environment-for-guideline-based-decision-support-systems-for%C3%A2-outpatients-monitoring
#5
Elisa M Zini, Giordano Lanzola, Paolo Bossi, Silvana Quaglini
OBJECTIVES: We propose an architecture for monitoring outpatients that relies on mobile technologies for acquiring data. The goal is to better control the onset of possible side effects between the scheduled visits at the clinic. METHODS: We analyze the architectural components required to ensure a high level of abstraction from data. Clinical practice guidelines were formalized with Alium, an authoring tool based on the PROforma language, using SNOMED-CT as a terminology standard...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726937/novel-nanoparticles-with-cr-3-substituted-ferrite-for-self-regulating-temperature-hyperthermia
#6
Wei Zhang, Xudong Zuo, Ying Niu, Chengwei Wu, Shuping Wang, Shui Guan, S Ravi P Silva
For hyperthermia to be used under clinical conditions for cancer therapeutics the temperature regulation needs to be precise and accurately controllable. In the case of the metal nanoparticles used for such activities, a high coercivity is a prerequisite in order to couple more energy in a single heating cycle for efficient and faster differential heating. The chemically stable Co-Zn ferrite nanoparticles have typically not been used in such self-regulating hyperthermia temperature applications to date due to their low Curie temperature usually accompanied by a poor coercivity...
July 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28726645/chronic-myeloid-leukemia-expected-relapse-s-clinical-laboratory-indexes
#7
T Kirtava, D Ghirdaladze, T Vatsadze
Today Chronic Myeloid Leukemia (CML) relapse's final assessment and monitoring in the whole world is implemented by BCR-ABL gene quantitative detection - during the polymerase chain reaction (by PSR means). Implementation of this monitoring materially and technically is not often available and remission during years is being assessed using monthly clinical-laboratory data. Proceeding from this, the goal of our work was to find the clinical-laboratory features, indicating the expected relapse and require the urgent molecular research carry out...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726485/annals-express-20%C3%AE-and-20%C3%AE-dihydrocortisone-may-interfere-in-lc-ms-ms-determination-of-cortisol-in-saliva-and-urine
#8
Marlen Israelsson, Ralph Brattsand, Goran Brattsand
BACKGROUND: LC-MS/MS methods offer high selectivity in cortisol determinations. However, endogenous steroid metabolites may still interfere and compromise the results, for example in the diagnosis of Cushing´s syndrome. Erroneously elevated cortisol may, in particular, be misleading at the low concentrations found in salivary samples obtained at late night and after dexamethasone suppression. METHODS: Interferences in our LC-MS/MS method used for determination of cortisol in saliva and urine were identified by comparing their retention times and mass spectra with those of pure candidate substances...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28726374/impact-of-thermal-annealing-on-organic-photovoltaic-cells-using-regioisomeric-donor-acceptor-acceptor-molecules
#9
Tao Zhang, Han Han, Yunlong Zou, Ying-Chi Lee, Hiroya Oshima, Ken-Tsung Wong, Russell J Holmes
We report a promising set of donor-acceptor-acceptor (D-A-A) electron-donor materials based on coplanar thieno[3,2-b]/[2,3-b]indole, benzo[c][1,2,5]thiadiazole, and dicyanovinylene, which are found to show broadband absorption with high extinction coefficients. The role of the regioisomeric electron-donating thienoindole moiety on the physical and structural properties is examined. Bulk heterojunction (BHJ) organic photovoltaic cells (OPVs) based on the thieno[2,3-b]indole-based electron donor NTU-2, using C70 as an electron acceptor, show a champion power conversion efficiency of 5...
July 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28726156/remote-monitoring-and-consultation-of-inpatient-populations-with-diabetes
#10
REVIEW
Robert J Rushakoff, Joshua A Rushakoff, Zachary Kornberg, Heidemarie Windham MacMaster, Arti D Shah
PURPOSE OF REVIEW: Inpatient hyperglycemia is common and is linked to increased morbidity and mortality. We review current and innovative ways diabetes specialists consult in the management of inpatient diabetes. RECENT FINDINGS: With electronic medical records (EMRs), remote monitoring and intervention may improve the management of inpatient hyperglycemia. Automated reports allow monitoring of glucose levels and allow diabetes teams to intervene through formal or remote consultation...
September 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28726050/a-single-center-study-a%C3%AE-42-p-tau181-csf-ratio-to-discriminate-ad-from-ftd-in-clinical-setting
#11
Andrea Vergallo, Cecilia Carlesi, Cristina Pagni, Filippo Sean Giorgi, Filippo Baldacci, Lucia Petrozzi, Roberto Ceravolo, Gloria Tognoni, Gabriele Siciliano, Ubaldo Bonuccelli
Abnormal levels of beta amyloid (Aβ42) and tau protein concentrations in the cerebral spinal fluid (CSF) have been largely described in Alzheimer's disease (AD). Thus, CSF analysis of these biomarkers has been incorporated in recent AD diagnostic criteria, and it is increasingly performed for neurodegenerative dementia diagnostic workout in clinical setting. Nevertheless, the precise biomarkers CSF features in neurodegenerative dementia, either AD or Frontotemporal dementia (FTD), are still not fully clear today...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28725928/structural-modification-of-cuminaldehyde-thiosemicarbazone-increases-inhibition-specificity-toward-aflatoxin-biosynthesis-and-sclerotia-development-in-aspergillus-flavus
#12
Francesca Degola, Franco Bisceglie, Marianna Pioli, Sabrina Palmano, Lisa Elviri, Giorgio Pelosi, Tiziana Lodi, Francesco Maria Restivo
Aspergillus flavus is an opportunistic mold that represents a serious threat for human and animal health due to its ability to synthesize and release, on food and feed commodities, different toxic secondary metabolites. Among them, aflatoxin B1 is one of the most dangerous since it is provided with a strong cancerogenic and mutagenic activity. Controlling fungal contamination on the different crops that may host A. flavus is considered a priority by sanitary authorities of an increasing number of countries due also to the fact that, owing to global temperature increase, the geographic areas that are expected to be prone to experience sudden A...
July 19, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28725882/group-based-active-learning-of-classification-models
#13
Zhipeng Luo, Milos Hauskrecht
Learning of classification models from real-world data often requires additional human expert effort to annotate the data. However, this process can be rather costly and finding ways of reducing the human annotation effort is critical for this task. The objective of this paper is to develop and study new ways of providing human feedback for efficient learning of classification models by labeling groups of examples. Briefly, unlike traditional active learning methods that seek feedback on individual examples, we develop a new group-based active learning framework that solicits label information on groups of multiple examples...
May 2017: Proceedings of the ... International Florida AI Research Society Conference
https://www.readbyqxmd.com/read/28725848/exploring-inpatients-experiences-of-healing-and-healing-spaces-a-mixed-methods-study
#14
Lorissa MacAllister, Dawn Bellanti, Bonnie R Sakallaris
In order to understand a patient's healing experience it is essential to understand the elements that they, the patient, believes contributed to their healing. Previous research has focused on symptom reducers or contributors through environment such as stress. A person's experience of healing happens over time not instantaneous. Therefore, in this study, the interviews with patients happened after forty-eight hours of hospitalization. This mixed methods study describes the experiences of seventeen inpatients from two healthcare systems using a phenomenological approach combined with evidence based design evaluation methods to document the setting...
December 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28725791/quality-improvement-intervention-for-reduction-of-redundant-testing
#15
Alan M Ducatman, Danyel H Tacker, Barbara S Ducatman, Dustin Long, Peter L Perrotta, Hannah Lawther, Kelly Pennington, Owen Lander, Mary Warden, Conard Failinger, Kevin Halbritter, Ronald Pellegrino, Marney Treese, Jeffrey A Stead, Eric Glass, Lauren Cianciaruso, Konrad C Nau
Laboratory data are critical to analyzing and improving clinical quality. In the setting of residual use of creatine kinase M and B isoenzyme testing for myocardial infarction, we assessed disease outcomes of discordant creatine kinase M and B isoenzyme +/troponin I (-) test pairs in order to address anticipated clinician concerns about potential loss of case-finding sensitivity following proposed discontinuation of routine creatine kinase and creatine kinase M and B isoenzyme testing. Time-sequenced interventions were introduced...
January 2017: Acad Pathol
https://www.readbyqxmd.com/read/28725441/taking-the-lead-from-our-colleagues-in-medical-education-the-use-of-images-of-the-in-vivo-setting-in-teaching-concepts-of-pharmaceutical-science
#16
Louise E Curley, Julia Kennedy, Jordan Hinton, Ali Mirjalili, Darren Svirskis
Despite pharmaceutical sciences being a core component of pharmacy curricula, few published studies have focussed on innovative methodologies to teach the content. This commentary identifies imaging techniques which can visualise oral dosage forms in-vivo and observe formulation disintegration in order to achieve a better understanding of in-vivo performance. Images formed through these techniques can provide students with a deeper appreciation of the fate of oral formulations in the body compared to standard disintegration and dissolution testing, which is conducted in-vitro...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28725188/using-virtual-reality-to-assess-ethical-decisions-in-road-traffic-scenarios-applicability-of-value-of-life-based-models-and-influences-of-time-pressure
#17
Leon R Sütfeld, Richard Gast, Peter König, Gordon Pipa
Self-driving cars are posing a new challenge to our ethics. By using algorithms to make decisions in situations where harming humans is possible, probable, or even unavoidable, a self-driving car's ethical behavior comes pre-defined. Ad hoc decisions are made in milliseconds, but can be based on extensive research and debates. The same algorithms are also likely to be used in millions of cars at a time, increasing the impact of any inherent biases, and increasing the importance of getting it right. Previous research has shown that moral judgment and behavior are highly context-dependent, and comprehensive and nuanced models of the underlying cognitive processes are out of reach to date...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28724937/bootstrap-quantification-of-estimation-uncertainties-in-network-degree-distributions
#18
Yulia R Gel, Vyacheslav Lyubchich, L Leticia Ramirez Ramirez
We propose a new method of nonparametric bootstrap to quantify estimation uncertainties in functions of network degree distribution in large ultra sparse networks. Both network degree distribution and network order are assumed to be unknown. The key idea is based on adaptation of the "blocking" argument, developed for bootstrapping of time series and re-tiling of spatial data, to random networks. We first sample a set of multiple ego networks of varying orders that form a patch, or a network block analogue, and then resample the data within patches...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724423/effectiveness-and-cost-effectiveness-of-telephone-based-cognitive-behavioural-therapy-in-primary-care-study-protocol-of-tide-telephone-intervention-for-depression
#19
Birgit Watzke, Elisa Haller, Maya Steinmann, Daniela Heddaeus, Martin Härter, Hans-Helmut König, Karl Wegscheider, Thomas Rosemann
BACKGROUND: Despite the availability of evidence-based treatments for depression, a large proportion of patients remains untreated or adequate treatment is initiated with delay. This situation is particularly critical in primary care, where not only most individuals first seek help for their mental health problems, but also depressive disorders - particularly mild to moderate levels of severity - are highly prevalent given the high comorbidity of chronic somatic conditions and depression...
July 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28724359/the-burden-of-hiv-on-tuberculosis-patients-in-the-volta-region-of-ghana-from-2012-to-2015-implication-for-tuberculosis-control
#20
Eric Osei, Joyce Der, Richard Owusu, Philip Kofie, Wisdom Kudzo Axame
BACKGROUND: The impact of HIV on TB, and the implications for TB control, has been acknowledged as a public health challenge. It is imperative therefore to assess the burden of HIV on TB patients as an indicator for monitoring the control efforts of the two diseases in this part of the world. This study aimed at determining the burden of HIV infection in TB patients. METHODS: We conducted a retrospective review of TB registers in five districts of the Volta Region of Ghana...
July 19, 2017: BMC Infectious Diseases
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