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https://www.readbyqxmd.com/read/29141250/a-small-supernumerary-marker-derived-from-the-pericentromeric-region-of-chromosome-5-case-report-and-delineation-of-partial-trisomy-5p-phenotype
#1
Letizia Camerota, Mariabernarda Pitzianti, Diana Postorivo, Anna M Nardone, Claudio Ligas, Costanzo Moretti, Augusto Pasini, Francesco Brancati
A 17-year-old girl presented with a distinct phenotype mainly featuring craniofacial dysmorphism, including a disproportioned large, round, elongated face; hypertelorism; deep-set eyes with short palpebral fissures; obesity (BMI 37), and a neuropsychiatric disorder with high-functioning autism. Postnatal conventional cytogenetic analyses from peripheral blood revealed a mosaic small supernumerary marker chromosome (sSMC) with a mos 47,XX,+mar[7]/46,XX[43] karyotype. By cenM-FISH technique, the sSMC was identified as a ring derivative of chromosome 5...
November 16, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/29141034/structure-of-the-human-chromosome-interaction-network
#2
Sergio Sarnataro, Andrea M Chiariello, Andrea Esposito, Antonella Prisco, Mario Nicodemi
New Hi-C technologies have revealed that chromosomes have a complex network of spatial contacts in the cell nucleus of higher organisms, whose organisation is only partially understood. Here, we investigate the structure of such a network in human GM12878 cells, to derive a large scale picture of nuclear architecture. We find that the intensity of intra-chromosomal interactions is power-law distributed. Inter-chromosomal interactions are two orders of magnitude weaker and exponentially distributed, yet they are not randomly arranged along the genomic sequence...
2017: PloS One
https://www.readbyqxmd.com/read/29140989/joint-approach-based-on-clinical-and-imaging-features-to-distinguish-non-neoplastic-from-neoplastic-pituitary-stalk-lesions
#3
Ji Ye Lee, Ji Eun Park, Woo Hyun Shim, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim, Jeong Hoon Kim, Ho Sung Kim
PURPOSE: Distinguishing non-neoplastic pituitary stalk lesions (non-NPSLs) from neoplastic pituitary stalk lesions (NPSLs) is a major concern in guiding treatment for a thickened pituitary stalk. Our study aimed to aid provide preoperative diagnostic assistance by combining clinical and magnetic resonance imaging (MRI) findings to distinguish non-NPSLs from NPSLs. MATERIALS AND METHODS: We recruited 158 patients with thickened pituitary stalk lesions visible on MRI...
2017: PloS One
https://www.readbyqxmd.com/read/29140977/low-cost-and-open-source-multi-fluorescence-imaging-system-for-teaching-and-research-in-biology-and-bioengineering
#4
Isaac Nuñez, Tamara Matute, Roberto Herrera, Juan Keymer, Timothy Marzullo, Timothy Rudge, Fernán Federici
The advent of easy-to-use open source microcontrollers, off-the-shelf electronics and customizable manufacturing technologies has facilitated the development of inexpensive scientific devices and laboratory equipment. In this study, we describe an imaging system that integrates low-cost and open-source hardware, software and genetic resources. The multi-fluorescence imaging system consists of readily available 470 nm LEDs, a Raspberry Pi camera and a set of filters made with low cost acrylics. This device allows imaging in scales ranging from single colonies to entire plates...
2017: PloS One
https://www.readbyqxmd.com/read/29140701/the-hydrophobe-challenge-a-joint-experimental-and-computational-study-on-the-host-guest-binding-of-hydrocarbons-to-cucurbiturils-allowing-explicit-evaluation-of-guest-hydration-free-energy-contributions
#5
Khaleel I Assaf, Mara Florea, Jens Antony, Niel M Henriksen, Jian Yin, Andreas Hansen, Zheng-Wang Qu, Rebecca Sure, Dieter Klapstein, Michael K Gilson, Stefan Grimme, Werner M Nau
The host-guest complexation of hydrocarbons (22 guest molecules) with cucurbit[7]uril was investigated in aqueous solution by using the indicator displacement strategy. The binding constants (10(3)-10(9) M(-1)) increased with guest size, pointing to the hydrophobic effect and dispersion interactions as driving forces. The measured affinities provide unique benchmark data for the binding of neutral guest molecules. Consequently, a computational blind challenge, the HYDROPHOBE challenge, was conducted in order to allow a comparison with state-of-the-art computational methods for predicting host-guest affinity constants...
November 15, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29140497/integrating-complementary-and-traditional-practices-in-middle-eastern-supportive-cancer-care
#6
Eran Ben-Arye, Noah Samuels, Michel Daher, Ibrahim Turker, Omar Nimri, Maryam Rassouli, Michael Silbermann
The Middle East is a promising arena in which researchers can explore the interchange between cross-cultural traditional medicine and supportive cancer care, as provided within an integrative oncology setting. Integrative oncology research and clinical practice in this part of the world have been focusing, for the most part, on the use of herbal medicine and mind-body-spiritual modalities, both of which are deeply rooted in traditional medical care. A regional, multinational, and interdisciplinary collaboration is currently being undertaken as part of the academic activities of the Middle-East Research Group in Integrative Oncology (MERGIO)...
November 1, 2017: Journal of the National Cancer Institute. Monographs
https://www.readbyqxmd.com/read/29140254/semiconductor-of-spinons-from-ising-band-insulator-to-orthogonal-band-insulator
#7
Tohid Farajollahpour, Seyed Akbar Jafari
We use ionic Hubbard model to study the effects of strong correlations on a two-dimensional semiconductor. The spectral gap in the limit where on-site interactions are zero is set by the staggered ionic potential, while in the strong interaction limit it is set by the Hubbard U. Combining mean field solutions of the slave spin and slave rotor methods we propose two interesting gapped phases in between: (i) The insulating phase before the Mott phase can be viewed as gapping a non-Fermi liquid state of spinons by the staggered ionic potential...
November 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29140186/acute-effect-of-two-self-myofascial-release-protocols-on-hip-and-ankle-range-of-motion
#8
Amandda de Souza, Cristiano Gomes Sanchotene, Cristiano Moreira da Silva Lopes, Jader Alfredo Beck, Affonso Celso Kulevicz da Silva, Suzana Matheus Pereira, Caroline Ruschel
CONTEXT: Self-myofascial release (SMR) is an intervention popularly used by rehabilitation, fitness, and sports professionals to improve recovery and performance. In SMR, the athlete/patient himself applies pressure to the muscle and fascia, using various tools such as balls, rods, foam rolls and massagers. OBJECTIVE: This study aimed to evaluate the acute effect of two SMR protocols (short- and long-term) of the posterior thigh and calf muscles on hip and ankle range of motion (ROM) in physically active men...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29138687/analysis-of-the-biceps-brachii-muscle-by-varying-the-arm-movement-level-and-load-resistance-band
#9
Nuradebah Burhan, Mohammad 'Afif Kasno, Rozaimi Ghazali, Md Radzai Said, Shahrum Shah Abdullah, Mohd Hafiz Jali
Biceps brachii muscle illness is one of the common physical disabilities that requires rehabilitation exercises in order to build up the strength of the muscle after surgery. It is also important to monitor the condition of the muscle during the rehabilitation exercise through electromyography (EMG) signals. The purpose of this study was to analyse and investigate the selection of the best mother wavelet (MWT) function and depth of the decomposition level in the wavelet denoising EMG signals through the discrete wavelet transform (DWT) method at each decomposition level...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29137766/mild-synthesis-of-a-zn-ii-metal-organic-polymer-and-its-hybrid-with-activated-carbon-application-as-antibacterial-agent-and-in-water-treatment-by-using-sonochemistry-optimization-kinetic-and-isotherm-study
#10
Tahere Taghipour, Gholamreza Karimipour, Mehrorang Ghaedi, Arash Asfaram
In this work, a room temperature and short method (30min) for synthesis of nanosized rod-like metal organic polymer (MOP) has been described. Reaction of 1,4-phenylenedioxy diacetic acid with zinc salt leads to the formation of [Zn(C10H8O6)(H2O)4]n and subsequently was loaded on activated carbon following sonication and structurally characterized by FTIR, SEM, EDX and XRD analysis. The combination of this new composite with sonication was applied for rapid and efficient adsorption of Bromocresol Purple (BCP)...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29137757/improved-crystallization-of-ammonium-sulphate-using-ultrasound-assisted-approach-with-comparison-with-the-conventional-approach
#11
Ashish V Mohod, Parag R Gogate
In chemical processing industries, crystallization is one of the most important operations to obtain solid products with desired purity and characteristics. With distinct processing problems for the conventional approaches for crystallization, research into alternate approaches such as ultrasound assisted crystallization has been on the forefront. The present work deals with comparison of the conventional approach and ultrasound assisted approach for crystallization of ammonium sulphate followed by detailed understanding into the effect of important operating parameters (initial concentration, pH, agitation speed, depth of horn, and cooling approach) on the metastable zone width and average crystal size...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29137753/synthesis-of-nanocomposites-of-iron-oxide-gold-fe3o4-au-loaded-on-activated-carbon-and-their-application-in-water-treatment-by-using-sonochemistry-optimization-study
#12
Saideh Bagheri, Hossein Aghaei, Mehrorang Ghaedi, Arash Asfaram, Majid Monajemi, Ali Akbar Bazrafshan
This paper focuses on the finding best operational conditions using response surface methodology (RSM) for Rhodamine123 (R123) and Disulfine blue (DSB) dyes removal by ultrasound assisted adsorption onto Au-Fe3O4 nanoparticles loaded on activated carbon (Au-Fe3O4 NPs-AC). The influences of variables such as initial R123 (X1) and DSB concentration (X2), pH (X3), adsorbent mass (X4) and sonication time (X5) on their removal were investigated by small central composite design (CCD) under response surface methodology...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29136928/prediction-of-2-ehn-content-in-diesel-biodiesel-blends-using-ftir-and-chemometrics
#13
Dan Vrtiška, Pavel Šimáček
Quantification models based on the processing of FTIR spectra by partial least squares regression (PLS) were created in order to develop a method for the determination of 2-ethylhexyl nitrate (2-EHN) in diesel fuels. The set of standards was prepared using 2-EHN, biodiesel (FAME) and various mineral diesel fuels (2-EHN free). The standards were prepared in the concentration range of 2-EHN of 0-2436mgkg(-1). The set of the standards was divided into the calibration, validation and test sets. While the calibration set was used to build the model, validation set was used in order to optimize the model parameters...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29136906/comparison-of-common-components-analysis-with-principal-components-analysis-and-independent-components-analysis-application-to-spme-gc-ms-volatolomic-signatures
#14
Jihéne Bouhlel, Delphine Jouan-Rimbaud Bouveresse, Said Abouelkaram, Elisabeth Baéza, Catherine Jondreville, Angélique Travel, Jérémy Ratel, Erwan Engel, Douglas N Rutledge
The aim of this work is to compare a novel exploratory chemometrics method, Common Components Analysis (CCA), with Principal Components Analysis (PCA) and Independent Components Analysis (ICA). CCA consists in adapting the multi-block statistical method known as Common Components and Specific Weights Analysis (CCSWA or ComDim) by applying it to a single data matrix, with one variable per block. As an application, the three methods were applied to SPME-GC-MS volatolomic signatures of livers in an attempt to reveal volatile organic compounds (VOCs) markers of chicken exposure to different types of micropollutants...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29136842/application-of-micro-x-ray-fluorescence-and-micro-computed-tomography-to-the-study-of-laser-cleaning-efficiency-on-limestone-monuments-covered-by-black-crusts
#15
Giorgio S Senesi, Ignazio Allegretta, Carlo Porfido, Olga De Pascale, Roberto Terzano
Laser cleaning is widely used to remove black crusts from weathered limestone monuments. The cleaning efficiency is commonly tested using conventional analytical techniques, which do not allow to analyze the same sample before and after the treatment. In this paper, micro computed tomography (μ-CT) and micro X-ray fluorescence spectroscopy (μ-XRF) techniques were used for the first time to evaluate the laser cleaning efficiency on two different encrusted quoins collected from a limestone monument. Analyses were carried out non-destructively on the same portion of the two lithotypes before and after the treatment...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29136822/new-ti-imac-magnetic-polymeric-nanoparticles-for-phosphopeptide-enrichment-from-complex-real-samples
#16
Anna Laura Capriotti, Chiara Cavaliere, Francesca Ferraris, Valentina Gianotti, Michele Laus, Susy Piovesana, Katia Sparnacci, Riccardo Zenezini Chiozzi, Aldo Laganà
The work describes the preparation of a new magnetic phase for batch enrichment of phosphopeptides. The material exploits the advantages of magnetic solid phase extraction and couples them with the most employed approach for phosphopeptide enrichment, i.e. Ti(4+)-IMAC. In order to immobilize Ti(4+) ions on the surface of the magnetite nanoparticles, they were first covered by a silica shell and then modified to expose at the surface bromine containing groups. Glycidyl methacrylate was subsequently polymerized from these groups using the "grafting from" approach by the activator regenerated by electron transfer-atom transfer radical polymerization (ARGET-ATRP) technique...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29136813/isolation-of-236-u-and-239-240-pu-from-seawater-samples-and-its-determination-by-accelerator-mass-spectrometry
#17
Mercedes López-Lora, Elena Chamizo, María Villa-Alfageme, Santiago Hurtado-Bermúdez, Núria Casacuberta, Manuel García-León
In this work we present and evaluate a radiochemical procedure optimised for the analysis of (236)U and (239,240)Pu in seawater samples by Accelerator Mass Spectrometry (AMS). The method is based on Fe(OH)3 co-precipitation of actinides and uses TEVA® and UTEVA® extraction chromatography resins in a simplified way for the final U and Pu purification. In order to improve the performance of the method, the radiochemical yields are analysed in 1 to 10L seawater volumes using alpha spectrometry (AS) and Inductively Coupled Plasma Mass Spectrometry (ICP-MS)...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29136647/katanin-like-2-katnal2-functions-in-multiple-aspects-of-haploid-male-germ-cell-development-in-the-mouse
#18
Jessica E M Dunleavy, Hidenobu Okuda, Anne E O'Connor, D Jo Merriner, Liza O'Donnell, Duangporn Jamsai, Martin Bergmann, Moira K O'Bryan
The katanin microtubule-severing proteins are essential regulators of microtubule dynamics in a diverse range of species. Here we have defined critical roles for the poorly characterised katanin protein KATNAL2 in multiple aspects of spermatogenesis: the initiation of sperm tail growth from the basal body, sperm head shaping via the manchette, acrosome attachment, and ultimately sperm release. We present data suggesting that depending on context, KATNAL2 can partner with the regulatory protein KATNB1 or act autonomously...
November 14, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29136383/a-combined-td-dft-sos-cis-d-study-of-bophy-derivatives-with-potential-application-in-biosensing
#19
Miguel Ponce-Vargas, Cloé Azarias, Denis Jacquemin, Boris Le Guennic
A set of thirteen BOPHY dyes is studied through a hybrid TD-DFT-SOS-CIS(D) approach accounting for solvent effects, in order to shed light onto the structure-property relationships of these recently developed chromophores. In a first step, we calculate the absorption fluorescence crossing points with refined TD-DFT models considering the influences of both vibrational and solvent contributions. We found that the systematic overestimation of the 0-0 energies is effectively reduced by combining PCM-TD-DFT with a scaled opposite spin-configuration interaction singles with a double correction [SOS-CIS(D)]...
November 14, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29136230/high-dose-tl-dosimetry-of-reactor-neutrons
#20
Barbara Obryk, Klaudia Malik, Pawel Bilski, Andrzej Igielski, Jan Dankowski, Arkadiusz Kurowski, Rafal Prokopowicz, Krzysztof Pytel
Radiation dose was measured with set of TL dosimeters during checkout of neutron radiation hardness of the ORTEC preamplifier type 142A in the experiment at the MARIA nuclear reactor at the National Centre for Nuclear Research (NCBJ), Otwock-Świerk, Poland. Different types of LiF-based TL detectors have been used for measurements in order to evaluate neutron and non-neutron components of the radiation field in the reactor channel during exposure and to check their relevancy for dose measurements in the reactor environment...
November 10, 2017: Radiation Protection Dosimetry
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