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https://www.readbyqxmd.com/read/28088362/molecular-characterization-of-a-novel-orthomyxovirus-from-rainbow-and-steelhead-trout-oncorhynchus-mykiss
#1
William N Batts, Scott E LaPatra, Ryan Katona, Eric Leis, Terry Fei Fan Ng, Marine S O Brieuc, Rachel B Breyta, Maureen K Purcell, Carla M Conway, Thomas B Waltzek, Eric Delwart, James R Winton
A novel virus, rainbow trout orthomyxovirus (RbtOV), was isolated in 1997 and again in 2000 from commercially-reared rainbow trout (Oncorhynchus mykiss) in Idaho, USA. The virus grew optimally in the CHSE-214 cell line at 15°C producing a diffuse cytopathic effect; however, juvenile rainbow trout exposed to cell culture-grown virus showed no mortality or gross pathology. Electron microscopy of preparations from infected cell cultures revealed the presence of typical orthomyxovirus particles. The complete genome of RbtOV is comprised of eight linear segments of single-stranded, negative-sense RNA having highly conserved 5' and 3'-terminal nucleotide sequences...
January 11, 2017: Virus Research
https://www.readbyqxmd.com/read/28088356/advancing-the-prediction-accuracy-of-protein-protein-interactions-by-utilizing-evolutionary-information-from-position-specific-scoring-matrix-and-ensemble-classifier
#2
Lei Wang, Zhu-Hong You, Shi-Xiong Xia, Feng Liu, Xing Chen, Xin Yan, Yong Zhou
Protein-Protein Interactions (PPIs) are essential to most biological processes and play a critical role in most cellular functions. With the development of high-throughput biological techniques and in silico methods, a large number of PPI data have been generated for various organisms, but many problems remain unsolved. These factors promoted the development of the in silico methods based on machine learning to predict PPIs. In this study, we propose a novel method by combining ensemble Rotation Forest (RF) classifier and Discrete Cosine Transform (DCT) algorithm to predict the interactions among proteins...
January 11, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28088008/instruments-evaluating-the-quality-of-the-clinical-learning-environment-in-nursing-education-a-systematic-review-of-psychometric-properties
#3
REVIEW
Irene Mansutti, Luisa Saiani, Luca Grassetti, Alvisa Palese
BACKGROUND: The clinical learning environment is fundamental to nursing education paths, capable of affecting learning processes and outcomes. Several instruments have been developed in nursing education, aimed at evaluating the quality of the clinical learning environments; however, no systematic review of the psychometric properties and methodological quality of these studies has been performed to date. OBJECTIVES: The aims of the study were: 1) to identify validated instruments evaluating the clinical learning environments in nursing education; 2) to evaluate critically the methodological quality of the psychometric property estimation used; and 3) to compare psychometric properties across the instruments available...
January 4, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28086907/identification-of-the-main-determinants-of-abdominal-aorta-size-a-screening-by-pocket-size-imaging-device
#4
Roberta Esposito, Federica Ilardi, Vincenzo Schiano Lomoriello, Regina Sorrentino, Vincenzo Sellitto, Giuseppe Giugliano, Giovanni Esposito, Bruno Trimarco, Maurizio Galderisi
BACKGROUND: Ultrasound exam as a screening test for abdominal aorta (AA) can visualize the aorta in 99% of patients and has a sensitivity and specificity approaching 100% in screening settings for aortic aneurysm. Pocket Size Imaging Device (PSID) has a potential value as a screening tool, because of its possible use in several clinical settings. Our aim was to assess the impact of demographics and cardiovascular (CV) risk factors on AA size by using PSID in an outpatient screening. METHODS: Consecutive patients, referring for a CV assessment in a 6 months period, were screened...
January 13, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28086814/intestinal-helminth-co-infection-and-associated-factors-among-tuberculosis-patients-in-arba-minch-ethiopia
#5
Getaneh Alemu, Mohammedaman Mama
BACKGROUND: Helminths affect the outcome of tuberculosis by shifting cell mediated immune response to humoral and by total suppression of the host immune system. On the reverse, Mycobacterium infection favors immune escape of helminths. Therefore assessing helminth co-infection rate and predisposing factors in tuberculosis patients is mandatory to set strategies for better case management. METHODS: Facility based cross-sectional study was conducted in Arba Minch to assess the prevalence and associated factors of intestinal helminths among pulmonary tuberculosis patients from January to August, 2016...
January 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28086759/urinary-incontinence-and-its-association-with-functional-physical-and-cognitive-health-among-female-nursing-home-residents-in-switzerland
#6
Lea F Schumpf, Nathan Theill, David A Scheiner, Daniel Fink, Florian Riese, Cornelia Betschart
BACKGROUND: Specific knowledge of urinary incontinence (UI) and its interrelation with physical and cognitive health is essential to working towards prevention of UI and to improving quality of treatment and care. The purpose of this study was to determine the association between UI and the activities of daily living (ADL) hierarchy scale, the cognitive performance scale (CPS) and comorbid conditions. METHODS: The cross-sectional retrospective analysis of 357 nursing homes in Switzerland was based on data of the Minimum Data Set of the Resident Assessment Instrument 2...
January 13, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28081494/a-cockspur-for-the-dss-cells-erythrina-crista-galli-sensitizers
#7
Paula Enciso, Jean-David Decoppet, Michael Grätzel, Michael Wörner, Franco M Cabrerizo, María Fernanda Cerdá
Dye sensitized solar cells were assembled employing a mixture of anthocyanins extracted from red ceibo's flowers. At the literature different extraction procedures are reported to extract anthocyanins from natural products and sensitize the cells. In order to compare them, different methods were followed to set the cells under the same conditions. Assembled cells showed very interesting conversion efficiency values, reaching a 0.73% value for extracts purified using C18 column, in open cells under illumination using a solar light simulator, 1 sun, 1...
January 4, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28080054/bond-dissociation-energies-for-diatomic-molecules-containing-3d-transition-metals-benchmark-scalar-relativistic-coupled-cluster-calculations-for-twenty-molecules
#8
Lan Cheng, Jürgen Gauss, Branko Ruscic, Peter B Armentrout, John F Stanton
Benchmark scalar-relativistic coupled-cluster calculations for dissociation energies of the twenty diatomic molecules containing 3d transition metals in the 3dMLBE20 database (Xu et al., J. Chem. Theory Comput. 2015, 11, 2036) ) are reported. Electron correlation and basis set effects are systematically studied. The agreement between theory and experiment is in general satisfactory. For a subset of sixteen molecules, the standard deviation between computational and experimental values is 9 kJ/mol with the maximum deviation being 15 kJ/mol...
January 12, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28079863/the-modified-patient-enablement-instrument-a-portuguese-cross-cultural-adaptation-validity-and-reliability-study
#9
Mafalda Remelhe, Pedro M Teixeira, Irene Lopes, Luís Silva, Jaime Correia de Sousa
Enabling patients with asthma to obtain the knowledge, confidence and skills they need in order to assume a major role in the management of their disease is cost effective. It should be an integral part of any plan for long-term control of asthma. The modified Patient Enablement Instrument (mPEI) is an easily administered questionnaire that was adapted in the United Kingdom to measure patient enablement in asthma, but its applicability in Portugal is not known. Validity and reliability of questionnaires should be tested before use in settings different from those of the original version...
January 12, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28079798/clinical-and-genetic-factors-associated-with-warfarin-maintenance-dose-in-northern-chinese-patients-with-mechanical-heart-valve-replacement
#10
Rui Liu, Jian Cao, Qian Zhang, Xin-Miao Shi, Xiao-Dong Pan, Ran Dong
The effects of genetic variants on warfarin dosing vary among different ethnic groups, especially in the Chinese population. The objective of this study was to recruit patients through a rigorous experimental design and to perform a comprehensive screen to identify gene polymorphisms that may influence warfarin dosing in northern Han Chinese patients with mechanical heart valve replacement. Consenting patients (n = 183) with a stable warfarin dose were included in this study. Ninety-six single nucleotide polymorphisms (SNPs) in 30 genes involved in warfarin pharmacological pathways were genotyped using the Illumina SNP GoldenGate Assay, and their associations with warfarin dosing were assessed using univariate regression analysis with post hoc comparison using least significant difference analysis...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079705/prescribed-drinking-leads-to-better-cycling-performance-than-ad-libitum-drinking
#11
Costas N Bardis, Stavros A Kavouras, J D Adams, Nickos D Geladas, Demosthenis B Panagiotakos, Labros S Sidossis
: Drinking ad libitum during exercise often leads to dehydration ranging from -1 to -3% of body weight. PURPOSE: To study the effect of a prescribed hydration protocol matching fluid losses on a simulated 30-km criterium-like cycling performance in the heat (31.6±0.5 °C). METHOD: Ten elite, heat-acclimatized, male endurance cyclists (30±5 y, 76.5±7.2 kg, 1.81±0.07 m, VO2peak: 61.3±5.2 ml[BULLET OPERATOR]min[BULLET OPERATOR]kg, body fat: 10...
January 10, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28079200/a-molecular-dynamics-study-of-the-interaction-of-water-with-the-external-surface-of-silicalite-1
#12
Konstantin S Smirnov
The interaction of water with the hydroxylated (010) surface of silicalite-1 was studied by classical molecular dynamics simulations. Interatomic interactions in the system were described using a set of effective potentials combining well-tested BKS and SPC models. The extended force field is shown to correctly reproduce the structural, energy, and dynamical characteristics of the silica surface OH groups. The interaction of water with the hydrophilic silanols leads to an ordering of H2O molecules in the vicinity of the surface...
January 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28079029/coulomb-matrix-elements-in-multi-orbital-hubbard-models
#13
Jorg Bunemann, Florian Gebhard
Coulomb matrix elements are needed in all studies in solid-state theory that are based on Hubbard-type multi-orbital models. Due to symmetries, the matrix elements are not independent. We determine a set of independent Coulomb parameters for a $d$-shell and an $f$-shell and all point groups with up to $16$ elements ($O_h$, $O$, $T_d$, $T_h$, $D_{6h}$, and $D_{4h}$). Furthermore, we express all other matrix elements as a function of the independent Coulomb parameters. Apart from the solution of the general point-group problem we investigate in detail the spherical approximation and first-order corrections to the spherical approximation...
January 12, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28078845/effect-of-low-energy-light-irradiation-by-light-emitting-diode-on-u937-cells
#14
G Spoto, V De Iuliis, M Petrini, V Flati, J Di Gregorio, D Vitale, M Caruso, V Dadorante, M Ciarmoli, I Robuffo, S Martinotti, E Toniato
Photobiomodulation (PBM) can induce a set of different biological modulators either in vitro or in vivo. Experimental evidence has highlighted the role of light effects on the mechanisms related to inflammation, apoptosis and autophagy. The goal of this project was the evaluation of PBM on U937, an established cell line of histiocytic lymphoma origin. Several aspects of modulation of proinflammatory pathways were analyzed and autophagic and proapoptotic mechanisms related to low laser light exposure of cells were studied...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28078068/efficacy-of-emg-bioimpedance-triggered-functional-electrical-stimulation-on-swallowing-performance
#15
Corinna Schultheiss, Thomas Schauer, Holger Nahrstaedt, Rainer O Seidl, Jehoschua Bieler
In order to support swallowing, the efficacy of functional electrical stimulation for different stimulation settings of the submental musculature has been investigated. The stimulation was administrated at rest and synchronously to voluntary initiated swallows. The onset of a swallow was detected in real-time by a combined electromyography/ bioimpedance measurement at the neck in order to trigger the stimulation. The amplitude and speed of larynx elevation caused by the FES has been assessed by the observed change in bioimpedance whereas a reduction of bioimpedance corresponds to an increase in larynx elevation...
September 15, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28077904/regadenoson-in-myocardial-perfusion-study-first-institutional-experiences-in-bosnia-and-herzegovina
#16
Nermina Beslic, Renata Milardovic, Amera Sadija, Sejla Ceric, Zeljka Raic
INTRODUCTION: Myocardial perfusion imaging (MPI) is widely used in the evaluation of known and suspected coronary artery disease (CAD). Imaging of heart in stress and rest enables the comparison of myocardial uptake of radiotracer in proportion to the needs and coronary flow, which is used for detection of perfusion defects. Exercise stress and pharmacologic agents are used for the stressing purpose. Novel pharmacologic stressor regadenoson is A2A selective adenosine agonist, which selectively binds to the adenosine receptors in coronary arteries causing coronary dilatation...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28077889/differential-diagnosis-of-erythmato-squamous-diseases-using-classification-and-regression-tree
#17
Keivan Maghooli, Mostafa Langarizadeh, Leila Shahmoradi, Mahdi Habibi-Koolaee, Mohamad Jebraeily, Hamid Bouraghi
INTRODUCTION: Differential diagnosis of Erythmato-Squamous Diseases (ESD) is a major challenge in the field of dermatology. The ESD diseases are placed into six different classes. Data mining is the process for detection of hidden patterns. In the case of ESD, data mining help us to predict the diseases. Different algorithms were developed for this purpose. OBJECTIVE: we aimed to use the Classification and Regression Tree (CART) to predict differential diagnosis of ESD...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28077843/orpha-orphic-functions-and-the-orphic-analyst-winnicott-s-regression-to-dependence-in-the-language-of-ferenczi
#18
Hayuta Gurevich
Early developmental trauma is imprinted in the psyche by survival fragmentation and dissociation. Traumatized patients need the analyst to be actively involved and allow for regression to dependence in order to strengthen, create and construct their psychic functioning and structure so that environmental failures will be contained and not rupture continuity of being. I suggest that Ferenczi's and Winnicott's ideas about regression to dependence in analysis are fundamental contributions to these quests, and that Ferenczi set the foundation, which Winnicott further explored and developed...
December 2016: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/28077762/inverse-problems-in-reduced-order-models-of-cardiovascular-haemodynamics-aspects-of-data-assimilation-and-heart-rate-variability
#19
Sanjay Pant, Chiara Corsini, Catriona Baker, Tain-Yen Hsia, Giancarlo Pennati, Irene E Vignon-Clementel
Inverse problems in cardiovascular modelling have become increasingly important to assess each patient individually. These problems entail estimation of patient-specific model parameters from uncertain measurements acquired in the clinic. In recent years, the method of data assimilation, especially the unscented Kalman filter, has gained popularity to address computational efficiency and uncertainty consideration in such problems. This work highlights and presents solutions to several challenges of this method pertinent to models of cardiovascular haemodynamics...
January 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28077692/reference-curves-for-the-australian-canadian-hand-osteoarthritis-index-in-the-middle-aged-dutch-population
#20
Féline P B Kroon, Sofia Ramiro, Patrick Royston, Saskia Le Cessie, Frits R Rosendaal, Margreet Kloppenburg
OBJECTIVE: The aim was to establish reference curves of the Australian/Canadian Hand Osteoarthritis Index (AUSCAN), a widely used questionnaire assessing hand complaints. METHODS: Analyses were performed in a population-based sample, The Netherlands Epidemiology of Obesity study (n = 6671, aged 45-65 years). Factors associated with AUSCAN scores were analysed with ordered logistic regression, because AUSCAN data were zero inflated, dividing AUSCAN into three categories (0 vs 1-5 vs >5)...
January 11, 2017: Rheumatology
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