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Primary cardiac Rhabdomyosarcoma

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https://www.readbyqxmd.com/read/27510683/pleomorphic-rhabdomyosarcoma-of-the-left-atrium-mimicking-myxoma
#1
Tanvi Aggarwal, Surbhi Goyal, Sufian Zaheer
Primary rhabdomyosarcoma (RMS) of the heart is a rare malignant tumor which has poor prognosis and survival despite surgery and adjuvant chemotherapy. The preoperative diagnosis is often difficult in view of nonspecific clinicoradiological findings. This report describes a case of a 60-year-old woman who was clinically diagnosed as left atrial myxoma. A diagnosis of pleomorphic RMS was made on histopathology after excision. Our case discusses the clinicopathological features and treatment options of cardiac RMS emphasizing the fact that histopathology and immunohistochemistry are essential to confirm the diagnosis of such an aggressive malignant tumor...
July 2016: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/27355140/recurrent-left-atrial-botyroid-rhabdomyosarcoma
#2
Günseli Abay, Cemal Kocaaslan, Rafet Günay, Meryem Doğan, Mahmut Murat Demirtaş
Primary heart tumors are extremely rare and their frequency ranges from approximately 0.01-0.3% in autopsy series. Nearly one quarter of all primary cardiac tumors are malignant tumors such as sarcoma. Rhabdomyosarcoma is the second most common malignant primary tumor of the heart following angiosarcoma.Primary cardiac tumors present with one or more of the symptoms of the classic triad: cardiac symptoms and signs resulting from intracardiac obstruction; signs of systemic embolization; and systemic or constitutional symptoms...
2016: Heart Surgery Forum
https://www.readbyqxmd.com/read/27344282/primary-cardiac-tumors-in-infants-and-children-surgical-strategy-and-long-term-outcome
#3
Eva Maria Delmo Walter, Mariano Francisco Javier, Frank Sander, Bernd Hartmann, Axel Ekkernkamp, Roland Hetzer
BACKGROUND: Primary cardiac tumors in infants and children are extremely rare; hence, there is very little literature available, and most knowledge is based on collections of case reports. This report is a comprehensive review of our 26-year experience with primary cardiac tumors in children with emphasis on surgical indications, strategies, and long-term outcome. METHODS: Between 1986 and 2012, 47 children (mean age 5.9 ± 2.4 months; range, 1 day to 17 years) underwent either subtotal or total resection of cardiac tumors (rhabdomyoma, 13; fibroma, 12; teratoma, 9; myxoma, 8; hemangioma, 2; rhabdomyosarcoma, 1; non-Hodgkin's lymphoma, 1; lymphangioma, 1)...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26690949/primary-rhabdomyosarcoma-of-the-diaphragm-with-cardiac-invasion
#4
Daniel Rodríguez Sánchez, Guillermo Carbonell López del Castillo, Águeda Bas Bernal, Gema Ruíz García, Nicolás Ortega López
No abstract text is available yet for this article.
March 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/26665113/intracardiac-metastatic-rhabdomyosarcoma
#5
Tae Ho Kim, Kiick Sung, Wook Sung Kim, Young Tak Lee, Pyo Won Park, Dong Seop Jeong
A 70-year-old man who visited Samsung Medical Center reported experiencing palpitation for 2 weeks. He had undergone excision of a mass in the right buttock due to rhabdomyosarcoma 7 years prior to this visit. Transesophageal echocardiography showed a pedunculated mass in the left ventricle, which was thought to be a vegetation of infective endocarditis, metastasis of the primary tumor, or thrombus. He underwent removal of the cardiac tumor, and the pathologic report was metastatic rhabdomyosarcoma. Thus, here, we report a rare case of metastatic rhabdomyosarcoma in the left ventricle...
December 2015: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26157957/acute-liver-failure-due-to-budd-chiari-syndrome-in-the-setting-of-cardiac-synovial-sarcoma
#6
Jonathan G Stine, Kelly Newton, Ajeet G Vinayak
Primary malignant tumors of the heart, specifically cardiac sarcomas, are rare and mainly diagnosed at autopsy. Acute Budd-Chiari syndrome is a recognized cause of acute liver failure and has been associated with several rare cardiac tumors: atrial myxoma, caval rhabdomyosarcoma, and primary cardiac adenocarcinoma. We present the first case of a fatal, highly differentiated cardiac synovial sarcoma that presented as acute liver failure from Budd-Chiari syndrome.
April 2015: ACG Case Reports Journal
https://www.readbyqxmd.com/read/25334726/a-malignant-cause-of-bilateral-pedal-edema
#7
Aasim Afzal, Jamil Alsahhar, Adam Mora
Cancer Student/Resident Case Report Posters IIISESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Primary sarcomas of the great vessels are rare. Presented is a case of an undifferentiated intimal sarcoma of the inferior vena cava (IVC) with extension to the right atrium, adrenal, and renal veins.CASE PRESENTATION: A 52-year-old woman presented with a one month history of fatigue, dyspnea and bilateral lower extremity edema. She was not in distress and hemodynamically stable...
October 1, 2014: Chest
https://www.readbyqxmd.com/read/24717305/cardiac-tumors-diagnosis-and-surgical-treatment
#8
REVIEW
Andreas Hoffmeier, Jürgen R Sindermann, Hans H Scheld, Sven Martens
BACKGROUND: Primary tumors of the heart are rare even in major cardiac surgery centers. Because of the low case numbers, there is an insufficient evidence base to determine the optimal treatment, particularly for malignant tumors. METHOD: The authors review the pertinent literature retrieved by a selective PubMed search on the terms "cardiac tumor," "heart tumor," "cardiac myxoma," and "cardiac sarcoma." They also present operative techniques and their own long-term results in 181 patients with cardiac tumors...
March 21, 2014: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/24314252/-primary-cardiac-embryonal-rhabdomyosarcoma-report-of-a-case
#9
Liang Guo, Zhen-yu Wang, Ya-bin Zou, Li-rong Bi
No abstract text is available yet for this article.
September 2013: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/23803244/a-case-of-primary-cardiac-rhabdomyosarcoma-with-surgical-removal-and-mitral-valve-repair
#10
Mehmet Yilmaz, Tamer Kehlibar, Ismail Yucesin Arslan, Hale Yaka Yilmaz, Ibrahim Arif Tarhan, Azmi Ozler
Primary cardiac tumors are rare. Nearly 25% of primary cardiac tumors are malignant, with rhabdomyosarcoma being the second most common primary sarcoma. Symptoms are variable, and the clinical presentation depends on the location and propagation of the tumor. Transthoracic and transesophageal echocardiography are preliminary tests in diagnosing the disease. Echocardiographic findings should be supported by other imaging methods. In appropriate cases, surgery combined with chemotherapy and radiotherapy is suggested...
June 2013: Heart Surgery Forum
https://www.readbyqxmd.com/read/23282617/-heart-autotransplantation-for-the-treatment-of-a-rhabdomyosarcoma-of-the-left-ventricle-report-of-one-case
#11
Rafael Selman A, Matías Ubilla S, Juan Espinoza H, Julio Muñoz P
Heart autotransplantation is an exceptional surgical technique used in the treatment of uncontrolled cardiac arrhythmias and primary unresectable cardiac tumors. We report a 28-year-old male with a rhabdomyosarcoma of the left ventricle, localized in the lateral and posterior wall, which involved the mitral valve and circumflex artery. After a complete study ruling out dissemination of the tumor, the patient was operated. Surgical exploration determined the unresectability of the tumor with the heart in situ...
June 2012: Revista Médica de Chile
https://www.readbyqxmd.com/read/23183945/paediatric-genitourinary-cancers-and-late-effects-of-treatment
#12
REVIEW
Karim T Sadak, Michael L Ritchey, Jeffrey S Dome
The most common childhood genitourinary cancers are Wilms tumour, rhabdomyosarcoma and germ cell tumour (GCT). Long-term survival rates for patients with these tumours are generally excellent, ranging from 80% to 100%. However, the high cure rates have highlighted the need to minimize the long-term complications of treatments (referred to as 'late effects'), which can be caused by the three treatment modalities used to treat genitourinary tumours: surgery, chemotherapy and radiation therapy. Serious late effects, such as death, second cancers and tumour recurrence, are uncommon but do occur occasionally...
January 2013: Nature Reviews. Urology
https://www.readbyqxmd.com/read/22792486/primary-cardiac-tumours-a-single-center-41-year-experience
#13
Christina Maria Steger, Thomas Hager, Elfriede Ruttmann
Primary cardiac tumours are extremely rare with the most commonest being left atrial myxomas. In general, surgical resection is indicated, whenever the tumour formation is mobile and embolization can be suspected. Within 17280 patients receiving heart surgery at the Innsbruck Medical University, 78 patients (0.45%) underwent tumourectomy of primary cardiac tumours. The majority of patients (63) suffered from a left or right atrial myxoma, 12 showed a papillary fibroelastoma of the valves at echocardiographical or histological examination, 1 suffered from a hemangioma, 1 from a chemodectoma, and another one from a rhabdomyosarcoma...
2012: ISRN Cardiology
https://www.readbyqxmd.com/read/22078057/spectrum-of-cardiac-tumors-excluding-myxoma-experience-of-a-tertiary-center-with-review-of-the-literature
#14
REVIEW
Narender Kumar, Shipra Agarwal, Arvind Ahuja, Prasenjit Das, Balram Airon, Ruma Ray
The aim of this study was to determine the histological spectrum of operated cardiac tumors, excluding myxoma, at a tertiary center in India. Between 1995 and 2010, we encountered 188 cases of operated cardiac tumors that had been subjected to histopathological examination. Morphological characterization was done by light microscopy along with histochemical stains. Immunohistochemistry using a panel of antibodies, i.e., vimentin, desmin, myogenin, smooth muscle actin (SMA), epithelial membrane antigen (EMA), cytokeratins, factor VIII-related antigen, S100-protein, synaptophysin, chromogranin, Bcl2, MIB-1, leukocyte common antigen (LCA), CD 3, CD20, CD34, and CD 99 (MIC-2) was performed wherever applicable...
December 15, 2011: Pathology, Research and Practice
https://www.readbyqxmd.com/read/21616279/magnetic-resonance-imaging-of-cardiac-tumors-part-2-malignant-tumors-and-tumor-like-conditions
#15
REVIEW
Kiran Randhawa, Arul Ganeshan, Edward T D Hoey
Cardiovascular magnetic resonance imaging (CMRI) is the reference noninvasive imaging technique for assessment and characterization of a suspected cardiac or juxta-cardiac mass. The multiplanar assessment of anatomy, tissue composition, and functional impact afforded by CMRI allows for early differentiation between a nonneoplastic mass and a tumor mass, be it benign or malignant. Malignant cardiac tumors have a poor prognosis; however, early detection and characterization confer some survival advantage, enabling early instigation of chemotherapy and/or consideration of a surgical debulking procedure...
July 2011: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/20338733/-malignant-primary-cardiac-tumors-in-childhood-and-adolescence
#16
B Fresneau, O Oberlin, L Brugières, D Valteau-Couanet, C Patte
Primary heart tumors are uncommon in children. The majority of them are benign, with only 10% malignant. Among malignant cardiac tumors, sarcoma (rhabdomyosarcoma, angiosarcoma, synovial sarcoma) and lymphoma (Burkitt's lymphoma, large B-cell lymphoma, lymphoblastic lymphoma) predominate. There are few published pediatric series on malignant primary cardiac tumors. We report here 3 observations of primary malignant cardiac tumors, 2 cases of sarcoma (angiosarcoma and synovial sarcoma) and 1 case of Burkitt's lymphoma...
May 2010: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/19830642/-atrial-tumors-in-cardiac-mri
#17
N Kraemer, J C Balzer, F Schoth, M Neizel, H Kuehl, R W Günther, G Krombach
Cardiac magnetic resonance imaging (MRI) is an important tool for the diagnosis of cardiac masses. Various cardiac tumors are predisposed to occurring in atrial structures. The aim of this review article is the description of atrial tumors and their morphological features in MRI. In general, cardiac tumors are rare: approximately 0.001 - 0.03 % in autopsy studies. About 75 % of them are benign. The most common cardiac tumor is the myxoma. They are predisposed to occur in the atria and show a characteristically strong hyperintense signal on T 2-wieghted images in MRI...
November 2009: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/19768306/surgical-treatment-of-primary-cardiac-rhabdomyosarcoma
#18
Ricardo de Carvalho Lima, Adriano Mendes, Elson Bezerra, Wilson Oliveira
The authors report a case of a 16-year-old man who presented progressive dyspnea. At that time the diagnosis of rheumatic fever with mitral valve involvement was performed. The bidimensional echocardiogram showed presence of mobile mass inside the left atrium. The tumor presented lobules, projecting into the left ventricle during the diastole and provoking turbulence. The patient underwent surgical resection with postoperative course needing re-operation for mitral valve replacement. Histopathology has proven that such tumor was a primary cardiac rhabdomyosarcoma and the early clinical diagnosis of rheumatic mitral valve disease was very difficult...
April 2009: Revista Brasileira de Cirurgia Cardiovascular
https://www.readbyqxmd.com/read/19760524/two-childhood-malignancies-in-an-elderly-individual-a-case-report-and-discussion
#19
REVIEW
Lohith S Bachegowda, Gayathri Nagaraj, Petros D Grivas, Lingyi Chen, Eugene Choi, Michael Styler
Rhabdomyosarcoma (RMS) is the most common soft-tissue tumor in childhood, but is extremely rare in elderly. We present a rare case of cardiac RMS, which developed 1 year after the diagnosis and management of acute lymphoblastic leukemia in a 68-year-old female. The occurrence of such phenomena is intriguing, especially in an individual without prior history of malignancy at a younger age. Through the review of the existing literature, we attempt to approach the pathogenesis and clinical manifestations of this rare clinical entity...
September 2010: Medical Oncology
https://www.readbyqxmd.com/read/19608082/imprint-cytology-of-primary-cardiac-sarcomas-a-report-of-3-cases
#20
Nobuzo Iwa, Kazuyoshi Masuda, Chikao Yutani, Tadao K Kobayashi
Primary cardiac sarcomas are rare instances and only occasionally documented in the cytologic literature. Usually, the diagnosis of these rare lesions can be made at echocardiography, aspiration biopsy cytology, cardiac biopsy, and open cardiac surgery (intraoperative diagnosis). In this study, cytologic configurations and immunohistochemistry for 3 primary cardiac sarcomas (rhabdomyosarcoma, angiosarcoma, and malignant fibrous histiocytoma) were revealed. In rhabdomyosarcoma (right ventricle), the tumor cells exhibited an anisocytotic spindle-shaped nuclei with hyperchromasia and an obscure cytoplasmic margin...
August 2009: Annals of Diagnostic Pathology
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