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Jyothi Embekkat Kaviyil, Raju Ravikumar
BACKGROUND: Tuberculous meningitis (TBM) is a condition that is caused by Mycobacterium tuberculosis complex and is difficult to diagnose due to the nonspecificity of the presentations. The study analyzed the different modes of diagnosis available in a developing country set up over a period of five years to understand the diagnostic values of the current conventional and automated methods of diagnosis of TBM among the patients suspected with chronic meningitis. METHODS: A total of 10,281 cerebrospinal fluid samples (CSF) were collected from suspected chronic meningitis patients, of which 790 samples were from individuals who had clinically suspected TBM...
July 2017: Indian Journal of Tuberculosis
Kirtilaxmi K Benachinmardi, R Ravikumar, B Indiradevi
INTRODUCTION: Biofilms are the source of persistent infections of many pathogenic microbes. They are responsible for nosocomial infection and also associated with many surgical conditions including indwelling medical devices such as ventriculoperitoneal shunt. A significant problem encountered in shunt procedures is obstruction followed by infection, with infection rate ranging from 2% to 27%, often with poor outcome. MATERIALS AND METHODS: This study was conducted in the Department of Neuromicrobiology at a tertiary neuroinstitute for 6 months from July 1 to December 31, 2014...
July 2017: Journal of Neurosciences in Rural Practice
Akepati Chandramuki, Neelam Khanna, Elena Shashkina, Natalia Kurepina, Barun Mathema, Barry N Kreiswirth, Manjunatha M Venkataswamy
AIMS: Specific genotypes of Mycobacterium tuberculosis (MTB) have been reported to cause outbreaks of pulmonary tuberculosis (TB) in geographical areas that are endemic to TB. However, since there is little epidemiological evidence on the association of particular genotypes that cause tuberculous meningitis (TBM), we sought to investigate the association of specific MTB strains with infection of the central nervous system (CNS). MATERIALS AND METHODS: We carried out a genetic characterisation of 89 MTB isolates from TBM patients at a Southern Indian tertiary neurocare centre and compared the genotypes with strains of pulmonary TB isolated from Indian immigrants in New York City...
April 2017: Indian Journal of Medical Microbiology
Kavitha Kumar, Prashant Giribhattanavar, Nagarathna Chandrashekar, Shripad Patil
Drug resistance has increased the difficulties in control of tuberculosis infection. The present study evaluated the clinical and laboratory features among tuberculous meningitis (TBM) patients and the drug susceptibility of Mycobacterium tuberculosis (M.tb) isolated from CSF. Out of 698 CSF samples, 176 (25.21%) were M.tb culture positive. Among the clinical signs and symptoms, fever, headache and altered sensorium were found to be statistically significant (P<0.05). ELISA was a better predictor of disease and found to be statistically significant (P<0...
December 2016: Diagnostic Microbiology and Infectious Disease
Daniel J Morgan, Lisa Pineles, Michelle Shardell, Atlisa Young, Katherine Ellingson, John A Jernigan, Hannah R Day, Kerri A Thom, Anthony D Harris, Eli N Perencevich
BACKGROUND: Hand hygiene is considered a critical factor in the prevention of health care-associated infections, and there have been many studies on ways to measure hand hygiene compliance. OBJECTIVE: Our objective was to evaluate the utility of estimating hand hygiene compliance using automated count technology versus direct human observation before and after a feedback intervention. We used a before and after quasi-experimental study over 30 weeks, in the setting of one 12-bed neurocare intensive care unit (NCICU) and one 15-bed cardiac intensive care unit (CCU) in a university, tertiary care hospital...
December 2012: American Journal of Infection Control
R Mani, S Pradhan, S Nagarathna, R Wasiulla, A Chandramuki
PURPOSE: Ten years retrospective study to evaluate the bacteriological spectrum of community acquired acute bacterial meningitis (CAABM). METHODS: Cerebrospinal fluid (CSF) samples from 385 clinically suspected cases of pyogenic meningitis were processed for cell counts, cytospin Gram stain, culture, antigen detection by latex agglutination (LAT) and antibiotic susceptibility test. Eighteen of these CSF samples were also subjected to a polymerase chain reaction (PCR) assay for detection of pneumococcal DNA...
April 2007: Indian Journal of Medical Microbiology
Gádor Cantón, David I Levy, Juan C Lasheras
BACKGROUND AND PURPOSE: The purpose of this study was to measure the changes in the intraaneurysmal fluid pressure and parent vessel flow characteristics resulting from packing the aneurysmal sac with hydrogel-coated coils. METHODS: Platinum coils coated with an expansible hydrogel were used to embolize a silicone model of the basilar tip aneurysm. The intraaneurysmal fluid pressure was measured with a NeuroCare Camino Pressure Micro-Probe at various packing ratios...
April 2005: AJNR. American Journal of Neuroradiology
C Loftus
The author has developed a new silicone carotid artery shunt (Loftus carotid endarterectomy shunt, Integra NeuroCare, Plainsboro, New Jersey) which offers several advantages over previously available commercial products. It is designed as an indwelling 15 cm (short) shunt, without an external loop. The silicone material makes for simple insertion and the ends are beveled and tapered to minimize dislodgement of any atheromatous material. At its proximal end a built-up bulb has been placed to facilitate securing by a Rummel tourniquet...
July 2000: Neurological Research
M B Kosier, P Minkler
The Ommaya reservoir (NeuroCare Group, Pleasant Prairie, WI) is an implanted ventricular device that permits delivery of drugs directly into the central nervous system (CNS). It is used in the management of patients whose cancer has invaded or may potentially invade the CNS; for pain management; for treatment of CNS infection; for monitoring of CNS pressure; and for cerebrospinal fluid sampling. Nursing care related to the Ommaya reservoir includes assessing patients, providing patient and family education, and, in some situations, accessing the device...
April 1999: Clinical Journal of Oncology Nursing
M Baker
The role of the voluntary sector is discussed from the standpoint of the Parkinson's Disease Society (PDS). The Society's Welfare Service is committed to listening to the needs of people with PD and their carers. One example of the "pump-priming" process is the Neurocare Project. Models of good practice should benefit increasing numbers of patients and carers throughout the country. Another form of "pump-priming" is the developing cooperation of charities, including the PDS, in "Neuro-Concern". However, charities must expect to be "pit props" to some extent...
March 1992: Journal of Neurology, Neurosurgery, and Psychiatry
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