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high frequency ultrasound

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https://www.readbyqxmd.com/read/29782294/the-value-of-high-frequency-20-mhz-ultrasonography-for-preoperative-measurement-of-cutaneous-melanoma-thickness
#1
Andrea Kozárová, Marek Kozár, Ingrid Tonhajzerová, Táňa Pappová, Eva Minariková
High-frequency ultrasonography has become an important diagnostic tool in dermatovenerology. It is used for assessment of the cutaneous layers in diverse benign and malignant skin lesions and diseases. Herein we present the practical value of preoperative measurement of cutaneous melanoma thickness, the explanation of the possible reasons for different sonographic and histologic Breslow thickness, and the practical importance of high-frequency 20 MHz ultrasonography in preoperative measurements of cutaneous melanoma thickness...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781990/fetal-mouse-cardiovascular-imaging-using-a-high-frequency-ultrasound-30-45mhz-system
#2
Marlin Touma
Congenital heart defects (CHDs) are the most common cause of childhood morbidity and early mortality. Prenatal detection of the underlying molecular mechanisms of CHDs is crucial for inventing new preventive and therapeutic strategies. Mutant mouse models are powerful tools to discover new mechanisms and environmental stress modifiers that drive cardiac development and their potential alteration in CHDs. However, efforts to establish the causality of these putative contributors have been limited to histological and molecular studies in non-survival animal experiments, in which monitoring the key physiological and hemodynamic parameters is often absent...
May 5, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781183/a-comparison-of-1-and-3-2-mhz-low-intensity-pulsed-ultrasound-on-osteogenesis-on-porous-titanium-alloy-scaffolds-an-in-vitro-and-in-vivo-study
#3
Lifang Feng, Xiaohan Liu, Hongjuan Cao, Limei Qin, Wentao Hou, Lin Wu
OBJECTIVES: Low-intensity pulsed ultrasound (LIPUS) combined with porous scaffolds can be used as a new therapy to treat bone defect repair. The aim of this study was to evaluate the effects of 1 and 3.2 MHz LIPUS on osteogenesis on porous Ti64 alloy scaffolds for both in vitro and in vivo studies. METHODS: Scaffolds were randomly divided into the high-frequency ultrasound group, low-frequency ultrasound group, and control group. Mouse pre-osteoblast cells were cultured with porous Ti-6Al-4V scaffolds in vitro to evaluate cell proliferation and differentiation...
May 21, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29774894/value-of-diffusion-weighted-imaging-for-monitoring-tissue-change-during-magnetic-resonance-guided-high-intensity-focused-ultrasound-therapy-in-bone-applications-an-ex-vivo-study
#4
Sharon L Giles, Jessica M Winfield, David J Collins, Ian Rivens, John Civale, Gail R Ter Haar, Nandita M deSouza
Background: Magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) can palliate metastatic bone pain by periosteal neurolysis. We investigated the value of diffusion-weighted imaging (DWI) for monitoring soft tissue changes adjacent to bone during MR-guided HIFU. We evaluated the repeatability of the apparent diffusion coefficient (ADC) measurement, the temporal evolution of ADC change after sonication, and its relationship with thermal parameters. Methods: Ex-vivo experiments in lamb legs ( n = 8) were performed on a Sonalleve MR-guided HIFU system...
2018: European radiology experimental
https://www.readbyqxmd.com/read/29774074/placenta-specific-drug-delivery-by-trophoblast-targeted-nanoparticles-in-mice
#5
Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li, Jie Chen, Tianxia Xiao, Balamurali K Ambati, Lintao Cai, Qing Yang, Nihar R Nayak, Jian Zhang, Xiujun Fan
Rationale: The availability of therapeutics to treat pregnancy complications is severely lacking, mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium falciparum- infected erythrocytes (IEs) accumulate in the placenta by adhering to chondroitin sulfate A (CSA) on the surfaces of trophoblasts. Based on this principle, we have developed a method for targeted delivery of payloads to the placenta using a synthetic placental CSA-binding peptide (plCSA-BP) derived from VAR2CSA, a CSA-binding protein expressed on IEs...
2018: Theranostics
https://www.readbyqxmd.com/read/29770302/percutaneous-microwave-thermosphere-ablation-of-pancreatic-tumours
#6
Anna Maria Ierardi, Pierpaolo Biondetti, Andrea Coppola, Enrico Maria Fumarola, Alberto Magenta Biasina, Salvatore Alessio Angileri, Gianpaolo Carrafiello
Background: In oncologic field, thermo-ablative procedures have spread more and more. Percutaneous microwave ablation (MWA) showed same benefits and some advantages over radiofrequency ablation (RFA). To date, a disadvantage of both was the not totally predictable size and shape of ablation volume. The aim of this study was to assess feasibility and safety of MWA in nonresectable pancreatic head cancer using a new technology of MW with high power (100 W) and frequency of 2,450 MH. Methods: Five patients with pancreatic head cancer treated with percutaneous MWA under ultrasound guidance were retrospectively reviewed...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29762755/obstructive-sleep-apnea-during-rem-sleep-is-associated-with-early-signs-of-atherosclerosis-in-women
#7
Mirjam Ljunggren, Eva Lindberg, Karl A Franklin, Patrik Öhagen, Marita Larsson, Jenny Theorell-Haglöw, Tord Naessén
Study Objectives: While obstructive sleep apnea (OSA) is associated with overall cardiovascular disease and mortality, the association with atherosclerotic cardiovascular disease is less clear, especially in women. Recently, it has been suggested that OSA during REM sleep, associated with long apneas and deep desaturations, could have severe cardio-metabolic consequences. The aim of this study was to investigate whether OSA during REM sleep is associated with early signs of atherosclerosis in a population-based sample of women...
May 14, 2018: Sleep
https://www.readbyqxmd.com/read/29761991/-study-of-neuronal-spike-frequency-adaptation-with-transcranial-magneto-acoustical-stimulation
#8
Yi Yuan, Na Pang, Yudong Chen, Hongbao Sun, Xiaoli Li
Transcranial magneto-acoustical stimulation (TMAS), utilizing focused ultrasound and a magnetostatic field to generate an electric current in tissue fluid to regulate the activities of neurons, has high spatial resolution and penetration depth. The neuronal spike-frequency adaptation plays an important role in the treatment of neural information. In this paper, we study the effects of ultrasonic intensity, magnetostatic field intensity and ultrasonic frequency on the neuronal spike-frequency adaptation based on the Ermentrout neuron model...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29758547/ultrasound-assisted-gene-and-photodynamic-synergistic-therapy-with-multifunctional-foxa1-sirna-loaded-porphyrin-microbubbles-for-enhancing-therapeutic-efficacy-for-breast-cancer
#9
Ranran Zhao, Xiaolong Liang, Bo Zhao, Min Chen, Renfa Liu, Sujuan Sun, Xiuli Yue, Shumin Wang
To improve the non-invasive therapeutic efficacy for ER positive breast cancer (ER+ BC), we fabricated a multifunctional FOXA1 loaded porphyrin microbubble to combine photodynamic therapy (PDT) and gene therapy of FOXA1 knockdown (KD) with ultrasound targeted microbubble destruction (UTMD) technology under the guidance of contrast enhanced ultrasound (CEUS). Cationic porphyrin microbubbles (CpMBs) were firstly fabricated from a porphyrin grafted lipid with two cationic amino groups (PGL-NH2) and fluorocarbon inert gas of C3 F8 ...
May 3, 2018: Biomaterials
https://www.readbyqxmd.com/read/29752922/a-non-inferiority-randomized-controlled-trial-to-compare-transabdominal-and-transvaginal-sonography-for-eligibility-assessment-prior-to-medical-abortion
#10
Annie Fu, Caitlin E Weber, Emma Gilmore, Anne R Davis, Gregory Hirsch, Carolyn L Westhoff
OBJECTIVES: To compare transabdominal sonography (TAS) to transvaginal sonography (TVS) in medical abortion eligibility assessment; specifically to measure how often clinicians chose to order additional testing for eligibility assessment following TAS and TVS, and to look for differences by patient and clinician characteristics. Also, to compare patient acceptability between the two modalities. STUDY DESIGN: This pragmatic multi-site randomized non-inferiority trial compared TAS to TVS at 10 New York City and New Jersey health centers that provide medical abortion...
May 9, 2018: Contraception
https://www.readbyqxmd.com/read/29752231/temporal-neuromodulation-of-retinal-ganglion-cells-by-low-frequency-focused-ultrasound-stimulation
#11
Qiuju Jiang, Guofeng Li, Huixia Zhao, Wenlong Sheng, Lan Yue, Min Su, Shijun Weng, Leanne Lai-Hang Chan, Qifa Zhou, Mark S Humayun, Weibao Qiu, Hairong Zheng
Significant progress has been made recently in treating neurological blindness using implantable visual prostheses. However, implantable medical devices are highly invasive and subject to many safety, efficacy, and cost issues. The discovery that ultrasound (US) may be useful as a noninvasive neuromodulation tool has aroused great interest in the field of acoustic retinal prostheses (ARPs). We have investigated the responsiveness of rat retinal ganglion cells (RGCs) to low-frequency focused US stimulation (LFUS) at 2...
May 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29750046/improvement-of-dermal-parameters-in-aged-skin-after-oral-use-of-a-nutrient-supplement
#12
Flávia Alvim Sant'Anna Addor, Juliana Cotta Vieira, Camila Sirieiro Abreu Melo
Purpose: Skin aging is a progressive and degenerative process caused by a decrease in the physiological functions of the skin tissue. In addition, environmental factors as well as concomitant diseases and lifestyle (nutrition, sedentary lifestyle, smoking, etc) negatively impact the aging process. An association between oral administration of collagen peptides combined with vitamin C and extracts of Hibiscus sabdariffa and Aristotelia chilensis (Delphynol® ) (Eximia Firmalize Age complex® ) on dermal thickness was studied and the improvement in aging signs was evaluated...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29739516/high-rate-treatment-of-hospital-wastewater-using-activated-sludge-process-induced-by-high-frequency-ultrasound
#13
Nasim Karami, Parviz Mohammadi, Aliakbar Zinatizadeh, Farzaneh Falahi, Nasrin Aghamohammadi
The biomass concentration of conventional activated sludge (CAS) process due to low sludge sedimentation in clarifiers is limited to 3000 mg/L. In this study, high-frequency ultrasound wave (1.8 MHz) was applied to enhance the CAS process performance using high Mixed Liquor Suspended Solid (MLSS) concentration. The study conducted using a pilot scale CAS bioreactor (with and without ultrasound) and their performance for treating a hospital wastewater were compared. Experimental conditions were designed based on a Central Composite Design (CCD)...
September 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29739309/performance-evaluation-of-adaptive-imaging-based-on-multiphase-apodization-with-cross-correlation-a-pilot-study-in-abdominal-ultrasound
#14
Junseob Shin, Yu Chen, Harshawn Malhi, Frank Chen, Jesse Yen
Degradation of image contrast caused by phase aberration, off-axis clutter, and reverberation clutter remains one of the most important problems in abdominal ultrasound imaging. Multiphase apodization with cross-correlation (MPAX) is a novel beamforming technique that enhances ultrasound image contrast by adaptively suppressing unwanted acoustic clutter. MPAX employs multiple pairs of complementary sinusoidal phase apodizations to intentionally introduce grating lobes that can be used to derive a weighting matrix, which mostly preserves the on-axis signals from tissue but reduces acoustic clutter contributions when multiplied with the beamformed radio-frequency (RF) signals...
May 1, 2018: Ultrasonic Imaging
https://www.readbyqxmd.com/read/29738919/feasibility-of-low-frequency-ultrasound-imaging-using-pulse-compressed-parametric-ultrasound
#15
Hideyuki Nomura, Hideo Adachi, Tomoo Kamakura
When using high-frequency (HF) ultrasound in sonography, attenuation due to the viscosity of the medium limits the available imaging depth, and strong reflection and scattering from hard tissue, such as bone, render biological diagnosis very difficult. In order to resolve these problems, the feasibility of low-frequency (LF) parametric ultrasound imaging with high directivity was explored in the present study. A pulse compression technique was applied to chirp-modulated parametric ultrasound waves in the frequency band of 100-500 kHz generated from modulated primary ultrasound waves with a center frequency of 2...
April 23, 2018: Ultrasonics
https://www.readbyqxmd.com/read/29734682/partial-discharge-ultrasound-detection-using-the-sagnac-interferometer-system
#16
Yu Wang, Xiaomin Li, Yan Gao, Hongjuan Zhang, Dong Wang, Baoquan Jin
Partial discharge detection is crucial for electrical cable safety evaluation. The ultrasonic signals frequently generated in the partial discharge process contains important characteristic information. However, traditional ultrasonic transducers are easily subject to strong electromagnetic interference in environments with high voltages and strong magnetic fields. In order to overcome this problem, an optical fiber Sagnac interferometer system is proposed for partial discharge ultrasound detection. Optical fiber sensing and time-frequency analysis of the ultrasonic signals excited by the piezoelectric ultrasonic transducer is realized for the first time...
May 4, 2018: Sensors
https://www.readbyqxmd.com/read/29733282/color-and-vector-flow-imaging-in-parallel-ultrasound-with-sub-nyquist-sampling
#17
Craig Madiena, Julia Faurie, Jonathan Poree, Damien Garcia
RF acquisition with a high-performance multichannel ultrasound system generates massive data sets in short periods of time, especially in "ultrafast" ultrasound when digital receive beamforming is required. Sampling at a rate four times the carrier frequency is the standard procedure since this rule complies with the Nyquist-Shannon sampling theorem and simplifies quadrature sampling. Bandpass sampling (or undersampling) outputs a bandpass signal at a rate lower than the maximal frequency without harmful aliasing...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29733278/design-and-characterization-of-an-acoustically-and-structurally-matched-3-d-printed-model-for-transcranial-ultrasound-imaging
#18
Chen Bai, Meiling Ji, Ayache Bouakaz, Yujin Zong, Mingxi Wan
For investigating human transcranial ultrasound imaging (TUI) through the temporal bone, an intact human skull is needed. Since it is complex and expensive to obtain one, it requires that experiments are performed without excision or abrasion of the skull. Besides, to mimic blood circulation for the vessel target, cellulose tubes generally fit the vessel simulation with straight linear features. These issues, which limit experimental studies, can be overcome by designing a 3-D-printed skull model with acoustic and dimensional properties that match a real skull and a vessel model with curve and bifurcation...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29732596/ultrasound-guided-posterior-antebrachial-cutaneous-nerve-block-technical-description-and-block-distribution-in-healthy-volunteers
#19
John J Finneran, NavParkash Sandhu
The posterior antebrachial cutaneous nerve branches from the radial nerve proximal to the elbow and supplies sensation to the posterior aspect of the forearm. With a high-frequency linear transducer, the posterior antebrachial cutaneous nerve was identified in 8 healthy volunteers. Under aseptic conditions and with an ultrasound-guided in-plane technique, 1% lidocaine was injected circumferentially around the nerve. In each participant, the block was successful, and neither incidental blocks of other nerves nor any other complications were observed...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29731939/innovative-one-step-melanoma-surgical-approach-osms-not-a-myth-it-s-a-reality-case-related-analysis-of-a-patient-with-a-perfect-clinical-outcome-reported-from-the-bulgarian-society-for-dermatologic-surgery-bulsds
#20
Georgi Tchernev, Svetoslav Chernin, Ilia Lozev, Torello Lotti, Konstantin Stavrov, Ivanka Temelkova, Ivan Pidakev
BACKGROUND: With the newly described one step melanoma surgical approach, some patient groups could be successfully treated within one surgical session. Depending on the tumour thickness (measured preoperatively) at a later stage (also depending on the ultrasound findings of the locoregional lymph nodes) the respective surgical intervention is planned with the respective field of surgical safety (one-stage melanoma surgery with or without removal of lymph nodes). The innovations could make to some extent some of the already existing algorithms more difficult (due to the introduction of a high-frequency ultrasound to determine the tumor thickness preoperatively as an absolute prerequisite for dermosurgical centres), but it would also lead with absolute certainty to better or least optimal results regarding the prognosis, the side effects and the financial factor also...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
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