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Pelvic inflammatory disease treatment

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https://www.readbyqxmd.com/read/29686882/pyosalpinges-after-hysterosalpingography-in-a-patient-with-lower-genital-tract-infection-and-managed-by-laparoscopic-surgery-in-a-resource-low-tertiary-hospital-case-report-and-literature-review
#1
Thomas Obinchemti Egbe, Fidelia Mbi Kobenge, Metogo Mbengono Junette Arlette, Eugene Belley-Priso
Background: Pyosalpinges (a complication of pelvic inflammatory disease) is infection of the fallopian tubes and the morbidity associated with it has major health implications. We are reporting a case of pyosalpinges diagnosed after hysterosalpingography and managed by laparoscopic surgery at the Douala General Hospital, Cameroon. Case presentation: A 29-year-old single woman, an assistant nurse of the Douala tribe in Cameroon. She is G1P0010 and came to our attention because of secondary infertility of three years duration...
2018: Fertility Research and Practice
https://www.readbyqxmd.com/read/29681986/anti-inflammatory-effect-of-feiyangchangweiyan-capsule-on-rat-pelvic-inflammatory-disease-through-jnk-nf-%C3%AE%C2%BA-b-pathway
#2
Yao Li, Yang Liu, Qian Yang, Zhihui Shi, Yanhua Xie, Siwang Wang
Objectives: In this study, we aimed to illustrate the preventive effect and possible mechanisms of Feiyangchangweiyan capsule (FYCWYC) on rat pelvic inflammatory disease (PID) model. Methods: To construct the rat PID model, upper genital tract was infected by multipathogen, and then drugs were orally administered for 8 days. The histological examination, immunohistochemical analysis, and ELISA were carried out. Furthermore, Western blotting was used to analyze the expression of Akt, MAPKs, NF- κ B p65, and I κ B- α in uterus...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29680200/biological-feasibility-and-importance-of-a-gonorrhea-vaccine-for-global-public-health
#3
Leah R Vincent, Ann E Jerse
There is a growing public health interest in controlling sexually transmitted infections (STIs) through vaccination due to increasing recognition of the global disease burden of STIs and the role of STIs in women's reproductive health, adverse pregnancy outcomes, and the health and well-being of neonates. Neisseria gonorrhoeae has historically challenged vaccine development through the expression of phase and antigenically variable surface molecules and its capacity to cause repeated infections without inducing protective immunity...
April 18, 2018: Vaccine
https://www.readbyqxmd.com/read/29679814/prediction-of-recurrent-ectopic-pregnancy-a-five-year-follow-up-cohort-study
#4
Mohamed Ellaithy, Mufareh Asiri, Ahmed Rateb, Ahmed Altraigey, Khaled Abdallah
OBJECTIVE: To evaluate the value of different clinical risk factors in the prediction of recurrent ectopic pregnancies (REP). STUDY DESIGN: This cohort study was carried out at a tertiary-care maternity hospital in Saudi Arabia, between January 2010 and June 2017. All women with a primary ectopic pregnancy (EP) were consecutively recruited, thoroughly assessed and followed up for a minimum duration of five-years (5.6 ± 0.61 years) to diagnose the nature and location of the subsequent pregnancies...
April 10, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29617576/current-understanding-on-pharmacokinetics-clinical-efficacy-and-safety-of-progestins-for-treating-pain-associated-to-endometriosis
#5
Fabio Barra, Carolina Scala, Simone Ferrero
Introduction Endometriosis is a chronic estrogen and progestogen responsive inflammatory disease associated with pain symptoms and infertility. The medical therapy of endometriosis aims to induce decidualization within the hormonally dependent ectopic endometrium, and it is often administered to ameliorate women' pain symptoms or to prevent post-surgical disease recurrence. A variety of progestins have been used in monotherapy for the medical management of women with endometriosis. Areas covered This review aims to offer the reader a complete overview of pharmacokinetic (PK) and clinical efficacy of progestins for the treatment of endometriosis...
April 4, 2018: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/29595670/acupuncture-for-chronic-pelvic-inflammatory-disease-a-systematic-review-protocol
#6
Ying Cheng, Youcai Yuan, Yuhao Jin, Na Xu, Taipin Guo
BACKGROUND: Chronic pelvic inflammation disease (PID) is a difficult-to-treat gynecological disorder with complex etiologies. Acupuncture has been applied widely for treating chronic pelvic inflammation or chronic pelvic pain symptoms in China. The aim of this review is to undertake a systematic review to estimate the effectiveness and safety of acupuncture on chronic PID. METHODS: A literature search will be conducted electronically with date up to October 2018 in MEDLINE, Cochrane Library, EBASE, and CNKI databases, using combination subject terms of chronic pelvic pain (or chronic pelvic inflammation, and chronic pelvic pain symptoms, etc...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29587664/management-and-obstetric-outcomes-of-17-heterotopic-interstitial-pregnancies
#7
Yuan Jiang, Jie Chen, Huaijun Zhou, Mingming Zheng, Ke Han, Jingxian Ling, Xianghong Zhu, Xiaoqiu Tang, Rong Li, Ying Hong
BACKGROUND: Heterotopic interstitial pregnancy is a rare variant of heterotopic pregnancies, and it poses challenges in treating the heterotopic pregnancy and preserving the intrauterine pregnancy. However, there is no clear consensus regarding the optimal management. The aim of this study was to investigate the pregnancy outcomes of women diagnosed with heterotopic interstitial pregnancy. METHODS: A total of 17 women diagnosed with heterotopic interstitial pregnancy between July 2010 and December 2015 were included...
March 27, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29575959/pharmacological-management-of-interstitial-cystitis-bladder-pain-syndrome-and-the-role-cyclosporine-and-other-immunomodulating-drugs-play
#8
Teruyuki Ogawa, Osamu Ishizuka, Tomohiro Ueda, Pradeep Tyagi, Michael B Chancellor, Naoki Yoshimura
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a symptomatic disorder characterized by pelvic pain and urinary frequency. Immunological responses are considered as one of the possible etiologies of IC/BPS. In this review, we focused on emerging targets, especially on those modulating immunological mechanisms for the treatments of IC/BPS. Area covered: This review was based on the literature search of PubMed/MEDLINE, for which key words following bladder pain syndrome, interstitial cystitis, and/or cyclosporine A (CyA) were used...
April 9, 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29523046/serum-procalcitonin-levels-together-with-clinical-features-and-inflammatory-markers-in-women-with-tubo-ovarian-abscess-for-discriminating-requirements-for-surgery-for-full-recovery
#9
Kenan Karaca, Enis Ozkaya, Meryem Kurek Eken, Ilgi Uygun, Sule Yıldırım Kopuk, Murat Alpay
Tubo-ovarian abscess (TOA) coexists in 15% of cases with pelvic inflammatory disease. Medical treatment is the first line of approach in women with TOA, however, 25% of cases fail to respond to antibiotics, therefore, these cases need to undergo surgical intervention. We aimed to determine factors leading to failure of medical treatment in women diagnosed with TOA. According to our results among 144 women, 27 cases required surgical intervention for full recovery. None of the demographic, sonographic or laboratory findings, including procalcitonin level, had significant predictive value for the failure of medical treatment in women with TOA...
March 9, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29510963/-conventional-analgesics-and-non-pharmacological-multidisciplinary-therapeutic-treatment-in-endometriosis-cngof-has-endometriosis-guidelines
#10
J-M Wattier
A major symptom of endometriosis is pelvic pain with a wide range of intensity, rhythm, type, and expression, without clearly established relationship between pain and the disease. Endometriosis-associated pain has physical, psychological/behavioral and social consequences with a significant impact on patient quality-of-life in relation with the biopsychosocial model of chronic pain. Pain assessment in all of its dimensions, as well as assessing the consequences of pain is therefore a crucial part of therapeutic management...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29483122/aminomethyl-spectinomycins-as-therapeutics-for-drug-resistant-gonorrhea-and-chlamydial-co-infections
#11
Michelle M Butler, Samanthi L Waidyarachchi, Kristie L Connolly, Ann E Jerse, Weirui Chai, Richard E Lee, Stephan A Kohlhoff, Dean L Shinabarger, Terry L Bowlin
Bacterial sexually transmitted infections are widespread and common, with Neisseria gonorrhoeae (gonorrhea) and Chlamydia trachomatis (chlamydia) being the two most frequent causes. If left untreated, both infections can cause pelvic inflammatory disease, infertility, ectopic pregnancy and other sequelae. The recommended treatment for gonorrhea is ceftriaxone plus azithromycin (to empirically treat chlamydial co-infections). Antibiotic resistance to all existing therapies has developed in gonorrheal infections...
February 26, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29465704/gonococcal-and-chlamydial-cases-of-pelvic-inflammatory-disease-at-2-canadian-sexually-transmitted-infection-clinics-2004-to-2014-a-retrospective-cross-sectional-review
#12
Justin Z Chen, Jennifer Gratrix, Petra Smyczek, Penny Parker, Ron Read, Ameeta E Singh
One hundred thirteen patients with gonococcal and chlamydial pelvic inflammatory disease were reviewed at 2 Canadian sexually transmitted infection clinics. Most patients (81%) with pelvic inflammatory disease were diagnosed as having chlamydia alone. Three treatment failures were seen in patients treated with ofloxacin.
April 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29450875/-coexistence-of-polymyalgia-rheumatica-with-ankylosing-spondylitis-a-case-report
#13
Ali Aydeniz, Mazlum Serdar Akaltun, Ali Gür, Savaş Gürsoy
Ankylosing spondylitis is a chronic inflammatory disease that affects the spine and peripheral joints. Polymyalgia rheumatica is an inflammatory disease characterized by aching and prolonged morning stiffness mainly in the shoulder and pelvic girdles. Many other diseases may mimic polymyalgia rheumatica, and thus differential diagnosis is predominantly required. A wide variety of diseases, including spondyloarthropathies, may present polymyalgia-like symptoms, and two diseases rarely coexist. We present a case of a 54-year-old man who had been followed-up for ankylosing spondylitis and presented with pain in the shoulder and pelvic girdles, restricted movement, and morning stiffness for 2 months...
January 2018: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29404418/intravaginal-administration-of-interleukin-12-during-genital-gonococcal-infection-in-mice-induces-immunity-to-heterologous-strains-of-neisseria-gonorrhoeae
#14
Yingru Liu, Julianny Perez, Laura A Hammer, Heather C Gallagher, Magdia De Jesus, Nejat K Egilmez, Michael W Russell
It has previously been shown that genital tract infection with Neisseria gonorrhoeae in mice does not induce a state of protective immunity against reinfection but instead suppresses the development of adaptive immune responses against N. gonorrhoeae dependent on transforming growth factor beta (TGF-β) and interleukin 10 (IL-10). Intravaginal administration during gonococcal infection of IL-12 encapsulated in biodegradable microspheres (IL-12/ms) reverses the immunosuppression and promotes the production of gamma interferon (IFN-γ) and of specific antibodies in serum and genital secretions and accelerates clearance of the infection...
January 2018: MSphere
https://www.readbyqxmd.com/read/29383896/-effect-of-acupuncture-on-inflammatory-cytokines-in-patients-with-acute-pelvic-inflammatory-disease
#15
Dan Wu, Li-Yan Guo, Pei-Si Lu
OBJECTIVE: To observe the effect of acupuncture on inflammatory indices and symptoms in patients with acute pelvic inflammatory disease, and investigate its mechanism. METHODS: Seventy-nine patients with acute pelvic inflammatory disease were randomly assigned to a control group ( n =37) given conventional treatment and an observation group ( n =42) given conventional treatment and acupuncture therapy. In the observation group, acupionts of Zhongji(CV 3), Guanyuan(CV 4), Zigong(EX-CA 1), Zusanli(ST 36), Sanyinjiao(SP 6), etc...
January 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29382460/management-of-iatrogenic-urorectal-fistulae-in-men-with-pelvic-cancer
#16
Francisco E Martins, Natália M Martins, Luís Campos Pinheiro, Luís Ferraz, Luís Xambre, Tomé M Lopes
INTRODUCTION: Urorectal fistula (URF) is a devastating complication of pelvic cancer treatments and a surgical challenge for the reconstructive surgeon. We report a series of male patients with URF resulting from pelvic cancer treatments, specifically prostate (PCa), bladder (BCa), and rectal cancer (RCa), and explore the differences and impact on outcomes between purely surgical and non-surgical treatment modalities. METHODS: Between October 2008 and June 2015, 15 male patients, aged 59-78 years (mean 67), with URF induced by pelvic cancer treatments were identified in our institutions...
September 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29369931/identifying-acute-cervicitis-in-an-era-of-less-frequent-routine-gynecologic-examinations
#17
Margaret Allen
Acute inflammation of the uterine cervix can lead to serious problems such as pelvic inflammatory disease (PID), endometritis, and complications of pregnancy and childbirth. As intervals for routine gynecologic screening examinations lengthen, cervical infections, especially if asymptomatic, may be missed. Annual wellness examinations and other patient visits outside routine gynecologic cancer screening visits should include brief evaluation with sexual risk assessment and a gynecologic examination if indicated...
February 2018: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29369919/actinomycotic-endometritis
#18
Andres G Chiesa-Vottero
Seven cases of actinomycotic endometritis were identified among 28,906 endometrial biopsies performed in the last 10 yr. The patients' ages ranged from 44 to 85 yr old. An intrauterine device was in place from 7 to 44 yr. The reasons to perform the biopsies included abnormal uterine bleeding, malodor, prolapse, pelvic inflammatory disease, and suspicion of metastatic uterine sarcoma. Definitive identification of Actinomyces israelii by culture was obtained in 1 case only. Gram, Gomori methenamine silver, and Fite stains were useful in the differential diagnosis with pseudoactinomycotic granules, Nocardia, fungi, and other bacteria...
April 19, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29320327/atypical-sites-of-deeply-infiltrative-endometriosis-clinical-characteristics-and-imaging-findings
#19
Luciana P Chamié, Duarte Miguel Ferreira Rodrigues Ribeiro, Dario A Tiferes, Augusto Cesar de Macedo Neto, Paulo C Serafini
Endometriosis is defined as the presence of endometrial tissue that is located outside the uterine cavity and associated with fibrosis and inflammatory reaction. It is a polymorphic and multifocal disease with no known cure or preventive mechanisms. Patients may be asymptomatic or may experience chronic pelvic pain, dysmenorrhea, dyspareunia, or infertility. The pelvic cavity is the most common location for endometriotic implants, which usually affect the retrocervical space, ovaries, vagina, rectosigmoid colon, bladder dome, and round ligaments...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29295593/structural-and-immunological-characterization-of-novel-recombinant-momp-based-chlamydial-antigens
#20
Guillermo Madico, Olga Gursky, Jeff Fairman, Paola Massari
Chlamydia is the most common cause of bacterial sexually transmitted infections worldwide. While infections resolve with antibiotic treatment, this is often neglected in women due to frequent asymptomatic infections, leading to disease progression and severe sequelae (pelvic inflammatory disease, ectopic pregnancy, infertility). Development of a vaccine against Chlamydia is crucial. Whole organism-based vaccines have short-lived activity, serovar/subgroup-specific immunity and can cause adverse reactions in vaccinated subjects...
December 25, 2017: Vaccines
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