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https://www.readbyqxmd.com/read/28339588/mri-features-predict-survival-and-molecular-markers-in-diffuse-lower-grade-gliomas
#1
Hao Zhou, Martin Vallières, Harrison X Bai, Chang Su, Haiyun Tang, Derek Oldridge, Zishu Zhang, Bo Xiao, Weihua Liao, Yongguang Tao, Jianhua Zhou, Paul Zhang, Li Yang
Background.: Previous studies have shown that MR imaging features can be used to predict survival and molecular profile of glioblastoma. However, no study of a similar type has been performed on lower-grade gliomas (LGGs). Methods.: Presurgical MRIs of 165 patients with diffuse low- and intermediate-grade gliomas (histological grades II and III) were scored according to the Visually Accessible Rembrandt Images (VASARI) annotations. Radiomic models using automated texture analysis and VASARI features were built to predict isocitrate dehydrogenase 1 (IDH1) mutation, 1p/19q codeletion status, histological grade, and tumor progression...
January 24, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28336681/accuracy-and-reliability-of-stroke-diagnosis-in-the-pediatric-emergency-department
#2
Mark T Mackay, Adriana Yock-Corrales, Leonid Churilov, Paul Monagle, Geoffrey A Donnan, Franz E Babl
BACKGROUND AND PURPOSE: Access to acute stroke interventions in the emergency department (ED) relies on correct clinical diagnosis. Our aims were to determine the accuracy and reliability of pediatric ED physician diagnosis of childhood stroke and other conditions presenting with brain attack symptoms. METHODS: Prospective study of consecutive children aged 1 month to 18 years presenting to the ED from June 2009 to December 2010 with focal neurological deficits...
March 23, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28331325/a-chinese-version-of-the-psychotic-symptom-rating-scales-psychometric-properties-in-recent-onset-and-chronic-psychosis
#3
Wai-Tong Chien, Isabella Yuet-Ming Lee, Li-Qun Wang
The purpose of this study was to test the reliability, validity, and factor structure of a Chinese version of the Psychotic Symptom Rating Scale (PSYRATS) in 198 and 202 adult patients with recent-onset and chronic psychosis, respectively. The PSYRATS has been translated into different language versions and has been validated for clinical and research use mainly in chronic psychotic patients but not in recent-onset psychosis patients or in Chinese populations. The psychometric analysis of the translated Chinese version included assessment of its content validity, semantic equivalence, interrater and test-retest reliability, reproducibility, sensitivity to changes in psychotic symptoms, internal consistency, concurrent validity (compared to a valid psychotic symptom scale), and factor structure...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28329819/development-of-a-physical-environmental-observational-tool-for-dining-environments-in-long-term-care-settings
#4
Habib Chaudhury, Heather Keller, Kaylen Pfisterer, Lillian Hung
Purpose: This paper presents the first standardized physical environmental assessment tool titled Dining Environment Audit Protocol (DEAP) specifically designed for dining spaces in care homes and reports the results of its psychometric properties. Items rated include: adequacy of lighting, glare, personal control, clutter, staff supervision support, restraint use, and seating arrangement option for social interaction. Two scales summarize the prior items and rate the overall homelikeness and functionality of the space...
February 20, 2017: Gerontologist
https://www.readbyqxmd.com/read/28325712/enlight-a-comprehensive-quality-and-therapeutic-potential-evaluation-tool-for-mobile-and-web-based-ehealth-interventions
#5
Amit Baumel, Keren Faber, Nandita Mathur, John M Kane, Fred Muench
BACKGROUND: Studies of criteria-based assessment tools have demonstrated the feasibility of objectively evaluating eHealth interventions independent of empirical testing. However, current tools have not included some quality constructs associated with intervention outcome, such as persuasive design, behavior change, or therapeutic alliance. In addition, the generalizability of such tools has not been explicitly examined. OBJECTIVE: The aim is to introduce the development and further analysis of the Enlight suite of measures, developed to incorporate the aforementioned concepts and address generalizability aspects...
March 21, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28323659/stimulus-induced-rhythmic-periodic-or-ictal-discharges-in-coma-incidence-and-interrater-reliability-of-continuous-eeg-after-a-standard-stimulation-protocol-a-prospective-study
#6
Khalid A Alsherbini, Joao Mc-OʼNeil Plancher, David M Ficker, Brandon P Foreman, Opeolu M Adeoye, Jun Ying, Michael D Privitera
PURPOSE: Stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs) are often seen during continuous electroencephalographic (cEEG) monitoring in coma. Given their uncertain clinical significance, our prospective study evaluated incidence of SIRPIDs in comatose patients in the neuroscience intensive care unit (NSICU) who underwent a standard stimulation protocol and defined interreader reliability for cEEG. METHODS: Of 146 patients prospectively screened who underwent cEEG during a 6-month period, 53 patients were included and 93 patients were excluded...
March 17, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28319261/comparative-measurement-of-collagen-bundle-orientation-by-fourier-analysis-and-semiquantitative-evaluation-reliability-and-agreement-in-masson-s-trichrome-picrosirius-red-and-confocal-microscopy-techniques
#7
V Marcos-Garcés, M Harvat, P Molina Aguilar, A Ferrández Izquierdo, A Ruiz-Saurí
Measurement of collagen bundle orientation in histopathological samples is a widely used and useful technique in many research and clinical scenarios. Fourier analysis is the preferred method for performing this measurement, but the most appropriate staining and microscopy technique remains unclear. Some authors advocate the use of Haematoxylin-Eosin (H&E) and confocal microscopy, but there are no studies comparing this technique with other classical collagen stainings. In our study, 46 human skin samples were collected, processed for histological analysis and stained with Masson's trichrome, Picrosirius red and H&E...
March 20, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28314524/development-of-the-japanese-version-of-the-psychosocial-assessment-of-candidates-for-transplantation-in-allogeneic-hematopoietic-stem-cell-transplantation
#8
Saki Harashima, Ryo Yoneda, Takeshi Horie, Mami Kayano, Yosei Fujioka, Fumihiko Nakamura, Mineo Kurokawa, Kazuhiro Yoshiuchi
BACKGROUND: The Psychosocial Assessment of Candidates for Transplantation (PACT) is a validated instrument for evaluating psychosocial risk factors in transplant candidates. OBJECTIVES: This study examined reliability and validity of the Japanese version of the PACT (J-PACT). METHODS: PACT is a clinician-rated scale consisting of an initial rating, 8 subscales, and a final rating. J-PACT was developed through a translation and back-translation procedure...
January 19, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28306487/effects-of-various-factors-on-doppler-ultrasonographic-measurements-of-radial-and-coccygeal-arterial-blood-pressure-in-privately-owned-conscious-cats
#9
Jacqueline C Whittemore, Michael R Nystrom, Dianne I Mawby
OBJECTIVE To assess the effects of age, body condition score (BCS), and muscle condition score (MCS) on radial and coccygeal systolic arterial blood pressure (SAP) in cats. DESIGN Prospective randomized trial. ANIMALS 66 privately owned cats enrolled between May and December 2010. PROCEDURES BCS and MCS of cats were assessed by 2 investigators; SAP was measured via Doppler ultrasonic flow detector, with cats positioned in right lateral or sternal recumbency for measurements at the radial or coccygeal artery, respectively, with order of site randomized...
April 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28299882/systolic-ejection-click-versus-split-first-heart-sound-are-our-ears-deceiving-us
#10
Natalie M Hoeting, Courtney E McCracken, Michael McConnell, Denver Sallee, Glen J Iannucci, Matthew E Oster
OBJECTIVE: Bicuspid aortic valve (BAV) disease is associated with potential lifetime complications, but auscultation of a BAV click is commonly missed or mistaken for a benign split first heart sound. Our objective was to determine whether pediatric cardiologists could reliably distinguish between BAV clicks and benign split first heart sounds. DESIGN: Quality evaluation project using de-identified recordings from an outpatient pediatric cardiology clinic. OUTCOME MEASURES: Twenty-one cardiologists listened to five de-identified recordings of pediatric heart sounds (three with BAV clicks, two with mitral components of benign split first heart sounds) and indicated whether they believed each recording was a BAV or split first heart sound...
March 16, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28299554/comparison-of-different-techniques-for-removal-of-calcium-hydroxide-from-straight-root-canals-an-in-vitro-study
#11
Anne-Kathrin Pabel, Michael Hülsmann
To compare four different techniques for removal of calcium hydroxide from straight root canals. The present study used the design suggested by Lee et al. (Int Endod J 37:607-612, 32) and van der Sluis et al. (Int Endod J 40:52-57, 17). One-hundred and ten extracted human teeth with straight root canals were prepared to ISO-size 50 and split longitudinally. Two lateral grooves were prepared, filled with calcium hydroxide and the root halves reassembled in a muffle. Calcium hydroxide was removed using one of five techniques: (1) passive ultrasonic irrigation, (2) hydrodynamic irrigation using RinsEndo(®), (3) sonic irrigation using the EndoActivator(®), (4) motor-driven plastic brush (CanalBrush™), and (5) manual irrigation with a syringe as the control group...
March 15, 2017: Odontology
https://www.readbyqxmd.com/read/28299404/an-intra-and-interrater-reliability-and-agreement-study-of-vaginal-resting-pressure-pelvic-floor-muscle-strength-and-muscular-endurance-using-a-manometer
#12
Merete Kolberg Tennfjord, Marie Ellström Engh, Kari Bø
INTRODUCTION AND HYPOTHESIS: Manometry is commonly used to assess pelvic floor muscle (PFM) function. Aims of the study were to assess intra- and interrater reliability and agreement of vaginal resting pressure, PFM strength, and muscular endurance using a high-precision pressure transducer. METHODS: A convenient sample of 23 women was included. The participants were tested twice by two examiners on day 1 and retested after 1 week by one examiner. Vaginal resting pressure, PFM strength, and muscular endurance were measured by manometer (Camtech AS)...
March 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28299240/validation-of-the-total-visual-acuity-extraction-algorithm-tova-for-automated-extraction-of-visual-acuity-data-from-free-text-unstructured-clinical-records
#13
Douglas M Baughman, Grace L Su, Irena Tsui, Cecilia S Lee, Aaron Y Lee
PURPOSE: With increasing volumes of electronic health record data, algorithm-driven extraction may aid manual extraction. Visual acuity often is extracted manually in vision research. The total visual acuity extraction algorithm (TOVA) is presented and validated for automated extraction of visual acuity from free text, unstructured clinical notes. METHODS: Consecutive inpatient ophthalmology notes over an 8-year period from the University of Washington healthcare system in Seattle, WA were used for validation of TOVA...
March 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28298265/supervised-machine-learning-algorithms-can-classify-open-text-feedback-of-doctor-performance-with-human-level-accuracy
#14
Chris Gibbons, Suzanne Richards, Jose Maria Valderas, John Campbell
BACKGROUND: Machine learning techniques may be an effective and efficient way to classify open-text reports on doctor's activity for the purposes of quality assurance, safety, and continuing professional development. OBJECTIVE: The objective of the study was to evaluate the accuracy of machine learning algorithms trained to classify open-text reports of doctor performance and to assess the potential for classifications to identify significant differences in doctors' professional performance in the United Kingdom...
March 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28293099/a-comparison-of-colorimetric-assessment-of-vaginal-ph-with-nugent-score-for-the-detection-of-bacterial-vaginosis
#15
Matthew K Hoffman, Mrutyunjaya B Bellad, Umesh S Charantimath, Avinash Kavi, Jyoti M Nagmoti, Mahantesh B Nagmoti, Ashalata A Mallapur, Geetanjali M Katageri, Umesh Y Ramadurg, Sheshidhar G Bannale, Amit P Revankar, M S Ganachari, Richard J Derman, Shivaprasad S Goudar
Background. A Nugent score > 7 has been defined as the gold standard for the diagnosis for bacterial vaginosis (BV), though it is resource intensive and impractical as point of care testing. We sought to determine if colorimetric assessment of vaginal pH can accurately predict the occurrence of BV. Methods. We performed a planned subanalysis of 1,216 pregnant women between 13 0/7 and 19 6/7 weeks who underwent vaginal examination as part of a randomized controlled trial. Using a standardized technique, specimens were obtained for colorimetric assessment and two separate slides for Gram staining...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28291801/early-diagnosis-of-mild-cognitive-impairment-and-mild-dementia-through-basic-and-instrumental-activities-of-daily-living-development-of-a-new-evaluation-tool
#16
Elise Cornelis, Ellen Gorus, Ingo Beyer, Ivan Bautmans, Patricia De Vriendt
BACKGROUND: Assessment of activities of daily living (ADL) is paramount to determine impairment in everyday functioning and to ensure accurate early diagnosis of neurocognitive disorders. Unfortunately, most common ADL tools are limited in their use in a diagnostic process. This study developed a new evaluation by adopting the items of the Katz Index (basic [b-] ADL) and Lawton Scale (instrumental [i-] ADL), defining them with the terminology of the International Classification of Human Functioning, Disability and Health (ICF), adding the scoring system of the ICF, and adding the possibility to identify underlying causes of limitations in ADL...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28291407/an-assessment-of-the-most-reliable-method-to-estimate-the-sagittal-alignment-of-the-cervical-spine-analysis-of-a-prospective-cohort-of-138-cases
#17
Roland D Donk, Michael G Fehlings, Wim I M Verhagen, Hisse Arnts, Hans Groenewoud, André L M Verbeek, Ronald H M A Bartels
OBJECTIVE Although there is increasing recognition of the importance of cervical spinal sagittal balance, there is a lack of consensus as to the optimal method to accurately assess the cervical sagittal alignment. Cervical alignment is important for surgical decision making. Sagittal balance of the cervical spine is generally assessed using one of two methods; namely, measuring the angle between C-2 and C-7, and drawing a line between C-2 and C-7. Here, the best method to assess sagittal alignment of the cervical spine is investigated...
March 3, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28290234/preliminary-validation-study-of-the-russian-birmingham-cognitive-screen
#18
E Kuzmina, G W Humphreys, M J Riddoch, A A Skvortsov, B S Weekes
INTRODUCTION: The Birmingham Cognitive Screen (BCoS) is designed for use with individuals who have acquired language impairment following stroke. Our goal was to develop a Russian version of the BCoS (Rus-BCoS) by translating the battery following cultural and linguistic adaptations and establishing preliminary data on its psychometric properties. METHOD: Fifty patients with left-hemisphere stroke were recruited, of whom 98% were diagnosed with mild to moderate aphasia...
March 14, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28286594/locking-it-down-the-privacy-and-security-of-mobile-medication-apps
#19
Kelly Grindrod, Jonathan Boersema, Khrystine Waked, Vivian Smith, Jilan Yang, Catherine Gebotys
OBJECTIVE: To explore the privacy and security of free medication applications (apps) available to Canadian consumers. METHODS: The authors searched the Canadian iTunes store for iOS apps and the Canadian Google Play store for Android apps related to medication use and management. Using an Apple iPad Air 2 and a Google Nexus 7 tablet, 2 reviewers generated a list of apps that met the following inclusion criteria: free, available in English, intended for consumer use and related to medication management...
January 2017: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/28280769/development-and-reliability-of-the-basic-skill-assessment-tool-for-adolescents-with-autism-spectrum-disorder
#20
Maethisa Pongsaksri, Suchitporn Lersilp, Sumana Suchart
The purpose of this study was to improve upon the first version of the basic work skills assessment tool for adolescents with autism spectrum disorder (ASD) and examine interrater and intrarater reliability using Intraclass Correlation Coefficient (ICC). The modified tool includes 2 components: (1) three tasks measuring work abilities and work attitudes and (2) a form to record the number of verbal and nonverbal prompts. 26 participants were selected by purposive sampling and divided into 3 groups-group 1 (10 subjects, aged 11-13 years), group 2 (10, aged 14-16 years), and group 3 (6, aged 17-19 years)...
2017: TheScientificWorldJournal
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