keyword
MENU ▼
Read by QxMD icon Read
search

Dro

keyword
https://www.readbyqxmd.com/read/28732067/thromboembolic-adverse-event-study-of-combined-estrogen-progestin-preparations-using-japanese-adverse-drug-event-report-database
#1
Shiori Hasegawa, Toshinobu Matsui, Yuuki Hane, Junko Abe, Haruna Hatahira, Yumi Motooka, Sayaka Sasaoka, Akiho Fukuda, Misa Naganuma, Kouseki Hirade, Yukiko Takahashi, Yasutomi Kinosada, Mitsuhiro Nakamura
Combined estrogen-progestin preparations (CEPs) are associated with thromboembolic (TE) side effects. The aim of this study was to evaluate the incidence of TE using the Japanese Adverse Drug Event Report (JADER) database. Adverse events recorded from April 2004 to November 2014 in the JADER database were obtained from the Pharmaceuticals and Medical Devices Agency (PMDA) website (www.pmda.go.jp). We calculated the reporting odds ratios (RORs) of suspected CEPs, analyzed the time-to-onset profile, and assessed the hazard type using Weibull shape parameter (WSP)...
2017: PloS One
https://www.readbyqxmd.com/read/28718308/ulnar-shortening-versus-distal-radius-corrective-osteotomy-in-the-management-of-ulnar-impaction-after-distal-radius-malunion
#2
William R Aibinder, Ali Izadpanah, Bassem T Elhassan
BACKGROUND: Distal radius malunions lead to functional deficits. This study compares isolated ulnar shortening osteotomy (USO) to distal radius osteotomy (DRO) for the treatment of ulnar impaction syndrome following distal radius malunion. METHODS: We retrospectively reviewed 11 patients with extra-articular distal radius malunions treated for ulnar impaction with isolated USO. This group was compared to a 1:1 age- and sex-matched cohort treated with isolated DRO for the same indication...
January 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28639254/use-of-a-digital-phantom-developed-by-qiba-for-harmonizing-suvs-obtained-from-the-state-of-the-art-spect-ct-systems-a-multicenter-study
#3
Tadaki Nakahara, Hiromitsu Daisaki, Yasushi Yamamoto, Takashi Iimori, Kazuyuki Miyagawa, Tomoya Okamoto, Yoshiki Owaki, Nobuhiro Yada, Koichi Sawada, Ryotaro Tokorodani, Masahiro Jinzaki
BACKGROUND: Although quantitative analysis using standardized uptake value (SUV) becomes realistic in clinical single-photon emission computed tomography/computed tomography (SPECT/CT) imaging, reconstruction parameter settings can deliver different quantitative results among different SPECT/CT systems. This study aims to propose a use of the digital reference object (DRO), which is a National Electrical Manufacturers Association (NEMA) phantom-like object developed by the Quantitative Imaging Biomarker Alliance (QIBA) fluorodeoxyglucose-positron emission tomography technical committee, for the purpose of harmonizing SUVs in Tc-99m SPECT/CT imaging...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28598213/characterization-and-degradation-potential-of-diesel-degrading-bacterial-strains-for-application-in-bioremediation
#4
María Balseiro-Romero, Panagiotis Gkorezis, Petra S Kidd, Jonathan Van Hamme, Nele Weyens, Carmen Monterroso, Jaco Vangronsveld
Bioremediation of polluted soils is a promising technique with low environmental impact, which uses soil organisms to degrade soil contaminants. In this study, 19 bacterial strains isolated from a diesel-contaminated soil were screened for diesel-degrading potential, biosurfactant production, and biofilm formation abilities, all desirable characteristics when selecting strains for re-inoculation into hydrocarbon-contaminated soils. Diesel degradation rates were determined in vitro in minimal medium with diesel as the sole carbon source...
June 9, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28584878/a-population-based-digital-reference-object-dro-for-optimizing-dynamic-susceptibility-contrast-dsc-mri-methods-for-clinical-trials
#5
Natenael B Semmineh, Ashley M Stokes, Laura C Bell, Jerrold L Boxerman, C Chad Quarles
The standardization and broad-scale integration of dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) have been confounded by a lack of consensus on DSC-MRI methodology for preventing potential relative cerebral blood volume inaccuracies, including the choice of acquisition protocols and postprocessing algorithms. Therefore, we developed a digital reference object (DRO), using physiological and kinetic parameters derived from in vivo data, unique voxel-wise 3-dimensional tissue structures, and a validated MRI signal computational approach, aimed at validating image acquisition and analysis methods for accurately measuring relative cerebral blood volume in glioblastomas...
March 2017: Tomography: a Journal for Imaging Research
https://www.readbyqxmd.com/read/28544938/sex-steroids-and-metabolic-responses-in-mussels-mytilus-galloprovincialis-exposed-to-drospirenone
#6
Tiziana Cappello, Denise Fernandes, Maria Maisano, Andrea Casano, Marta Bonastre, Maria João Bebianno, Angela Mauceri, Salvatore Fasulo, Cinta Porte
Drospirenone (DRO) is a synthetic progestin derived from 17α-spironolactone with a pharmacological mechanism of action similar to progesterone. Despite its wide use as pharmaceutical and consequent continuous release into the aquatic environment, DRO effects have been poorly investigated on aquatic biota. In order to unravel the toxicity mechanisms of DRO, mussels Mytilus galloprovincialis were exposed for 7 days to different concentrations of DRO, namely 20ng/L (Low; L), 200ng/L (Medium; M), 2000ng/L (High; H) and 10μg/L (Super High; SH) nominal doses...
May 22, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28505233/addition-of-droperidol-to-prophylactic-ondansetron-and-dexamethasone-in-children-at-high-risk-for-postoperative-vomiting-a-randomized-controlled-double-blind-study
#7
N Bourdaud, C François, O Jacqmarcq, M-L Guye, J Jean, C Studer, C Engrand-Donal, J-M Devys, F Boutin, E Guyot, N Bouazza, J-M Treluyer, G A Orliaguet
Background: : The combination of dexamethasone (DEX), ondansetron (OND) and droperidol (DRO) is efficacious in preventing postoperative nausea and vomiting in adults, but has not been well assessed in children. Methods: : Children undergoing elective surgery under general anaesthesia and considered at high risk for postoperative vomiting (POV) were randomly assigned to receive a combination of DEX, OND and placebo (Group A) or a combination of DEX, OND and DRO (Group B)...
June 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28471198/-can-we-observe-ethnic-difference-in-basic-blood-tests-single-institution-data-from-cancer-prevention-programme-in-the-czech-republic
#8
M Řiháček, D Valík, R Vyzula, L Zdražilová Dubská
BACKGROUND: Laboratory tests are standard part of a routine check-up of current medical status and an important tool in diagnostic workup, in planning or evaluation of treatment, and disease monitoring. To reduce misdiagnosis, accurate reference intervals reflecting age, sex, ethnicity and other relevant clinical parameters must be established. We aimed to explore ethnic difference in basic blood parameters relevant for the Czech Republic. PATIENTS AND METHODS: The study was performed analyzing blood tests from 13,126 individuals in cancer prevention program...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28471197/-circulating-myeloid-suppressor-cells-and-their-role-in-tumour-immunology
#9
K Pilatova, E Budinská, B Bensciková, R Nenutil, R Šefr, L Fedorová, B Hanáková, V Brychtová, L Zdražilová Dubská
BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are heterogenic population of multipotent progenitors of myeloid lineage. For their immunosuppressive effect, MDSC are responsible for tumour escape from the host immune surveillance. Furthermore, MDSCs support tumour by promotion of angiogenesis and metastasis. Membrane markers of human MDSCs are myeloid markers CD11b and CD13, these cells are HLA-Drlow/- and expression of CD15 or CD14 differentiate them into granulocytic (Gr-MDSCs) and monocytic (Mo-MDSCs), resp...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28406522/inhibition-of-polyglutamine-aggregation-by-similar-huntingtin-n-terminal-sequences-prospective-molecules-for-preclinical-evaluation-in-huntington-s-disease
#10
Gunasekhar Burra, Ashwani Kumar Thakur
The mutant huntingtin protein (mHtt) fragments with expanded polyglutamine sequence forms microscopically visible aggregates in neurons, a hallmark of Huntington's disease (HD). The aggregation process and aggregates are possible targets of therapeutic intervention in HD. Due to lack of treatment and cure, the patients die within 15-20 years after the disease onset. Therefore, discovering therapeutic molecules that may either inhibit the aggregation mechanism or downregulate the toxic effects of mhtt are highly needed...
April 12, 2017: Biopolymers
https://www.readbyqxmd.com/read/28365524/pancreas-and-liver-uptake-of-new-radiolabeled-incretins-glp-1-and-exendin-4-in-models-of-diet-induced-and-diet-restricted-obesity
#11
Daniele Seo, Bluma Linkowski Faintuch, Erica Aparecida de Oliveira, Joel Faintuch
INTRODUCTION: Radiolabeled GLP-1 and its analog Exendin-4, have been employed in diabetes and insulinoma. No protocol in conventional Diet-Induced Obesity (DIO), and Diet-Restricted Obesity (DRO), has been identified. Aiming to assess pancreatic beta cell uptake in DIO and DRO, a protocol was designed. METHODS: GLP-1-βAla-HYNIC and HYNIC-βAla-Exendin-4 were labeled with technetium-99m. Four Swiss mouse models were adopted: Controls (C), Alloxan Diabetes Controls (ADC), DIO and DRO...
June 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28298676/dehulling-and-microwave-pretreatment-effects-on-the-physicochemical-composition-and-antioxidant-capacity-of-virgin-rapeseed-oil
#12
Agnieszka Rękas, Aleksander Siger, Małgorzata Wroniak, Iwona Ścibisz, Dorota Derewiaka, Andrzej Anders
The effect of microwave heating (800 W) of whole and dehulled rapeseeds for 2 to 8 min was investigated in order to evaluate the impact of dehulling in conjunction with microwaving on the nutritional value, antioxidant activity and physicochemical properties of virgin rapeseed oil. Control oil produced from dehulled seeds (DRO) had higher amounts of bioactive compounds, such as tocochromanols and phytosterols, lower content of pigments, and higher content of primary and secondary oxidation products compared to oil pressed from whole seeds (WRO)...
March 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28192671/electron-deficient-dihydroindaceno-dithiophene-regioisomers-for-n-type-organic-field-effect-transistors
#13
Jean-David Peltier, Benoît Heinrich, Bertrand Donnio, Joëlle Rault-Berthelot, Emmanuel Jacques, Cyril Poriel
In this work, we wish to report the first member of a new family of organic semiconductors constructed on a meta dihydroindacenodithiophene core, that is, 2,2'-(2,8-dihexyl-4,6-dihydro-s-indaceno[1,2-b:7,6-b']dithiophene-4,6-diylidene)dimalononitrile (called meta-IDT(═C(CN)2)2). The properties of this molecule were studied in detail through a structure-properties relationship study with its regioisomer, that is, 2,2'-(2,7-dihexyl-4,9-dihydro-s-indaceno[1,2-b:5,6-b']dithiophene-4,9-diylidene)dimalononitrile (para-IDT(═C(CN)2)2) (see isomer structures in blue in Chart 2)...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28185463/-lymphoedema-following-regional-lymph-node-surgery-for-breast-cancer
#14
P Vrtělová, O Coufal, V Fait, L Gabrielová, O Zapletal
BACKGROUND: The treatment of breast cancer is based on the multimodal principle and surgery of regional lymph nodes is an inseparable part of this. Indication criteria are changing constantly folowing advances in other modalities. It is necessary to consider not only the diagnostic or therapeutic benefit but also to take into account adverse effects. Previous studies have demonstrated that axillary dissection (ALND) is burdened by a high frequency of chronic lymphoedema of the arm or chest wall; however, a considerable percentage of patients may also suffer from lymphoedema after sentinel lymph node biopsy (SLNB)...
December 0: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/27740509/distributed-robust-optimization-in-networked-system
#15
Shengnan Wang, Chunguang Li
In this paper, we consider a distributed robust optimization (DRO) problem, where multiple agents in a networked system cooperatively minimize a global convex objective function with respect to a global variable under the global constraints. The objective function can be represented by a sum of local objective functions. The global constraints contain some uncertain parameters which are partially known, and can be characterized by some inequality constraints. After problem transformation, we adopt the Lagrangian primal-dual method to solve this problem...
October 11, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27739580/establishing-motion-control-in-children-with-autism-and-intellectual-disability-applications-for-anatomical-and-functional-mri
#16
Alison D Cox, Javier Virues-Ortega, Flavia Julio, Toby L Martin
Excessive motion makes magnetic resonance imaging (MRI) extremely challenging among children with autism spectrum disorder (ASD). The medical risks of sedation establish the need for behavioral interventions to promote motion control among children with ASD undergoing MRI scans. We present a series of experiments aimed at establishing both tolerance of the MRI environment and a level of motion control that would be compatible with a successful MRI. During Study 1, we evaluated the effects of prompting and contingent reinforcement on compliance with a sequence of successive approximations to an MRI using a mock MRI...
January 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/27734468/comparing-fixed-amount-and-progressive-amount-dro-schedules-for-tic-suppression-in-youth-with-chronic-tic-disorders
#17
Matthew R Capriotti, Jennifer E Turkel, Rachel A Johnson, Flint M Espil, Douglas W Woods
Chronic tic disorders (CTDs) involve motor and/or vocal tics that often cause substantial distress and impairment. Differential reinforcement of other behavior (DRO) schedules of reinforcement produce robust, but incomplete, reductions in tic frequency in youth with CTDs; however, a more robust reduction may be needed to affect durable clinical change. Standard, fixed-amount DRO schedules have not commonly yielded such reductions, so we evaluated a novel, progressive-amount DRO schedule, based on its ability to facilitate sustained abstinence from functionally similar behaviors...
January 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/27707594/the-positive-impact-of-radiologic-imaging-on-high-stage-cutaneous-squamous-cell-carcinoma-management
#18
Emily Stamell Ruiz, Pritesh S Karia, Frederick C Morgan, Chrysalyne D Schmults
BACKGROUND: There is limited evidence on the utility of radiologic imaging for prognostic staging of cutaneous squamous cell carcinoma (CSCC). OBJECTIVE: Review utilization of radiologic imaging of high-stage CSCCs to evaluate whether imaging impacted management and outcomes. METHODS: Tumors classified as Brigham and Women's Hospital (BWH) tumor (T) stage T2B or T3 over a 13-year period were reviewed to identify whether imaging was performed and whether results affected treatment...
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27626237/life-cycle-of-petroleum-biodegradation-metabolite-plumes-and-implications-for-risk-management-at-fuel-release-sites
#19
Dawn A Zemo, Kirk T O'Reilly, Rachel E Mohler, Renae I Magaw, Catalina Espino Devine, Sungwoo Ahn, Asheesh K Tiwary
This paper summarizes the results of a 5-y research study of the nature and toxicity of petroleum biodegradation metabolites in groundwater at fuel release sites that are quantified as diesel-range "Total Petroleum Hydrocarbons" (TPH; also known as TPHd, diesel-range organics (DRO), etc.), unless a silica gel cleanup (SGC) step is used on the sample extract prior to the TPH analysis. This issue is important for site risk management in regulatory jurisdictions that use TPH as a metric; the presence of these metabolites may preclude site closure even if all other factors can be considered "low-risk...
July 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/27622130/differential-reinforcement-of-other-behaviour-for-the-reduction-of-severe-nail-biting
#20
Louise Heffernan, Danielle Lyons
The effects of differential reinforcement of other behaviour (DRO) were investigated for the treatment of severe self-injurious nail biting in an individual diagnosed with autism. A functional behaviour assessment (FBA) identified that the behaviour was maintained by automatic reinforcement. Following the implementation of the DRO procedure and access to reinforcing stimuli that were believed to provide similar sensory feedback to that of the self-injurious nail biting, the results indicate that the nail biting was successfully reduced and maintained at near zero levels...
September 2016: Behavior Analysis in Practice
keyword
keyword
112594
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"