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https://www.readbyqxmd.com/read/28437764/the-use-of-lithium-for-the-treatment-of-bipolar-disorder-recommendations-from-clinical-practice-guidelines
#1
Gin S Malhi, Danielle Gessler, Tim Outhred
BACKGROUND: Lithium is an effective mood stabilizer that is used principally for the management of bipolar disorder (BD). Its administration is complex and often requires sophisticated management and assiduous monitoring. When considering the use of lithium therapy for bipolar disorder, clinicians are advised to refer to recommendations outlined in clinical practice guidelines (CPGs); but because of varying emphases placed by different international CPGs, recommendations addressing the practical use of lithium lack consistency...
March 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28437177/periodontal-derived-mesenchymal-cell-sheets-promote-periodontal-regeneration-in-inflammatory-microenvironment
#2
Shujuan Guo, Jian Kang, Baohui Ji, Weihua Guo, Yi Ding, Yafei Wu, Weidong Tian
In this study, we investigated the periodontal regenerative potential of dental follicle cell (DFC) sheets and periodontal ligament cell (PDLC) sheets in the simulating inflammatory microenvironment of periodontitis, in order to confirm their regenerative potential for clinical application and explain the possible mechanism. The biological characteristics of DFC sheets and PDLC sheets were explored in lipopolysaccharid from Porphyromonas gingivalis (P. gingivalis LPS) induced inflammation microenvironment in vitro, then cell sheets were transplanted into canine periodontal defects with experimental periodontitis in situ for three months...
February 14, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28433034/direct-1-h-nmr-evidence-of-spin-rotation-coupling-as-a-source-of-para-%C3%A2-ortho-h2-conversion-in-diamagnetic-solvents
#3
Camilla Terenzi, Sabine Bouguet-Bonnet, Daniel Canet
At ambient temperature, conversion from 100% enriched para-hydrogen (p-H2; singlet state) to ortho-hydrogen (o-H2; triplet state) leads necessarily to the thermodynamic equilibrium proportions: 75% of o-H2 and 25% of p-H2. When p-H2 is dissolved in a diamagnetic organic solvent, conversion is very slow and can be considered as arising from nuclear spin relaxation phenomena. A first relaxation mechanism, specific to the singlet state and involving a combination of auto-correlation and cross correlation spectral densities, can be retained: randomly fluctuating magnetic fields due to inter-molecular dipolar interactions...
April 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28429158/food-insecurity-substance-use-and-sexual-transmission-risk-behavior-among-people-living-with-hiv-a-daily-level-analysis
#4
Jennifer A Pellowski, Tania B Huedo-Medina, Seth C Kalichman
People living with HIV in poverty have limited tangible and mental resources coupled with competing demands for these resources. Competing demands require individuals to make choices that may be beneficial to them in the short term but not in the long term. Past research has shown that food insecurity is related to sexual risk behaviors among people living with HIV. Individuals who are food insecure may sell sex in order to obtain food or lack of food may lead to a depletion of mental resources to negotiate safe sex...
April 20, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28428167/developing-a-patient-centered-mhealth-app-a-tool-for-adolescents-with-type-1-diabetes-and-their-parents
#5
Bree E Holtz, Katharine M Murray, Denise D Hershey, Julie K Dunneback, Shelia R Cotten, Amanda J Holmstrom, Arpita Vyas, Molly K Kaiser, Michael A Wood
BACKGROUND: Type 1 diabetes (T1D) afflicts approximately 154,000 people under 20 years of age. Three-quarters of adolescents are not achieving glycosylated hemoglobin (HbA1c) targets, which leads to negative health outcomes. Mobile health (mHealth), the use of technology in health, has been used successfully to improve health in many chronic conditions, including diabetes. OBJECTIVE: The purpose of this study was to use patient-centered research methods to inform and improve the design and functionality of our T1D app, MyT1DHero, and to provide insight for others who are designing a health app for adolescents and parents...
April 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28425206/considering-tangible-benefit-for-interdependent-donors-extending-a-risk-benefit-framework-in-donor-selection
#6
Sarah E Van Pilsum Rasmussen, Macey L Henderson, Jeffrey Kahn, Dorry Segev
From its infancy, live donor transplantation has operated within a framework of acceptable risk to donors. Such a framework presumes that risks of living donation are experienced by the donor while all benefits are realized by the recipient, creating an inequitable distribution that demands minimization of donor risk. We suggest that this risk-tolerance framework ignores tangible benefits to donor. A previously proposed framework more fully considers potential benefits to the donor and argues that risks and benefits must be balanced...
April 20, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28422298/bridging-type-2-diabetes-and-alzheimer-s-disease-assembling-the-puzzle-pieces-in-the-quest-for-the-molecules-with-therapeutic-and-preventive-potential
#7
REVIEW
Ana Marta de Matos, Maria Paula de Macedo, Amélia Pilar Rauter
Type 2 diabetes (T2D) and Alzheimer's disease (AD) are two age-related amyloid diseases that affect millions of people worldwide. Broadly supported by epidemiological data, the higher incidence of AD among type 2 diabetic patients led to the recognition of T2D as a tangible risk factor for the development of AD. Indeed, there is now growing evidence on brain structural and functional abnormalities arising from brain insulin resistance and deficiency, ultimately highlighting the need for new approaches capable of preventing the development of AD in type 2 diabetic patients...
April 19, 2017: Medicinal Research Reviews
https://www.readbyqxmd.com/read/28419714/young-people-s-beliefs-about-the-risk-of-bowel-cancer-and-its-link-with-physical-activity
#8
Katie V Newby, Chloe Cook, Susanne F Meisel, Thomas L Webb, Bernadette Fisher, Abi Fisher
OBJECTIVES: The primary objective was to explore young people's risk appraisals of bowel cancer, including whether they had a coherent understanding of the protective effects of physical activity (PA). A secondary objective was to examine whether the illness risk representations (IRRs) framework could be used to understand beliefs underlying bowel cancer risk appraisals. DESIGN: Qualitative. METHODS: Framework analysis of semi-structured interviews with 19 people aged 14-17 years...
April 17, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28419011/establishing-a-dedicated-difficult-vascular-access-team-in-the-emergency-department-a-needs-assessment
#9
Madeleine Whalen, Barbara Maliszewski, Diana-Lyn Baptiste
Peripheral vascular access is one of the most common procedures performed in emergency departments across the United States. Successful venipuncture is critical in providing timely diagnosis and treatments for patients. The aim of this article is to describe a needs assessment performed in a level-one academic emergency department to establish the need for a dedicated team for patients with difficult vascular access. Results from this assessment suggest that difficult vascular access represents tangible threats to patient safety and increased use of resources...
May 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28411922/postoperative-surveillance-for-renal-cell-carcinoma
#10
REVIEW
Suzanne B Merrill
Postoperative surveillance is an integral part of renal cell carcinoma (RCC) care. However, evidence supporting the practice is lacking. RCC guidelines offer disparate recommendations leading to variation in care. Recently, the effectiveness of guidelines has been questioned and a debate has ignited over whether current protocols merit optimization. Guidelines show limitations in RCC risk assessment, protocol stratification, and definition of duration of follow-up. Alternative strategies have addressed some of these limitations, but further analysis is warranted...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28410808/questioning-the-differences-between-general-public-vs-patient-based-preferences-towards-eq-5d-5l-defined-hypothetical-health-states
#11
Marko Ogorevc, Nika Murovec, Natacha Bolanos Fernandez, Valentina Prevolnik Rupel
The purpose of this article is to explore whether any differences exist between the general population and patient based preferences towards EQ-5D-5L defined hypothetical health states. The article discusses the role of adaptation and self-interest in valuing health states and it also contributes rigorous empirical evidence to the scientific debate on the differences between the patient and general population preferences towards hypothetical health states. Patient preferences were elicited in 2015 with the EQ-5D-5L questionnaire using time trade-off and discrete choice experiment design and compared to the Spanish general population preferences, which were elicited using identical methods...
March 28, 2017: Health Policy
https://www.readbyqxmd.com/read/28407460/depressive-symptoms-and-their-interactions-with-emotions-and-personality-traits-over-time-interaction-networks-in-a-psychiatric-clinic
#12
Laura N Semino, Josef Marksteiner, Gernot Brauchle, Erik Danay
Objective: Associations between depression, personality traits, and emotions are complex and reciprocal. The aim of this study is to explore these interactions in dynamical networks and in a linear way over time depending on the severity of depression. Methods: Participants included 110 patients with depressive symptoms (DSM-5 criteria) who were recruited between October 2015 and February 2016 during their inpatient stay in a general psychiatric hospital in Hall in Tyrol, Austria...
April 13, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28407260/the-value-of-nursing-care-a-concept-analysis
#13
Tracey K Dick, Patricia A Patrician, Lori A Loan
AIM: To report an analysis of the concept of value of nursing care. BACKGROUND: Value-based health care delivery and reimbursement models are focused on value as a product of quality and cost. Nursing care provides tangible and intangible contributions to patient and organizational outcomes. The nursing profession must be able to proactively and effectively communicate the value of nursing care. DESIGN: Concept analysis. DATA SOURCES: Thirty-five separate sources were chosen from database searches of CINAHL Complete and ABI/INFORM Complete...
April 13, 2017: Nursing Forum
https://www.readbyqxmd.com/read/28399883/role-of-self-efficacy-and-social-support-in-short-term-recovery-after-total-hip-replacement-a-prospective-cohort-study
#14
Espen Andreas Brembo, Heidi Kapstad, Sandra Van Dulmen, Hilde Eide
BACKGROUND: Despite the overall success of total hip replacement (THR) in patients with symptomatic osteoarthritis (OA), up to one-quarter of patients report suboptimal recovery. The aim of this study was to determine whether social support and general self-efficacy predict variability in short-term recovery in a Norwegian cohort. METHODS: We performed secondary analysis of a prospective multicenter study of 223 patients who underwent THR for OA in 2003-2004. The total score of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at 3 months after surgery was used as the recovery variable...
April 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28394157/mental-illness-disclosure-decision-making
#15
Rohini Pahwa, Anthony Fulginiti, John S Brekke, Eric Rice
Disclosure related to mental illness has been linked to various positive outcomes, including better mental health. However, many individuals with serious mental illness (SMI) continue to practice non-disclosure. Even though disclosure inherently occurs within the context of one's social relationships, research has generally conceptualized mental illness disclosure as an individual level phenomenon and neglected to consider preferences concerning to whom an individual discloses and the factors that influence this decision...
April 10, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28391197/virtual-character-animation-based-on-affordable-motion-capture-and-reconfigurable-tangible-interfaces
#16
Fabrizio Lamberti, Gianluca Paravati, Valentina Gatteschi, Alberto Cannavo, Paolo Montuschi
Software for computer animation is generally characterized by a steep learning curve, due to the entanglement of both sophisticated techniques and interaction methods required to control 3D geometries. This paper proposes a tool designed to support computer animation production processes by leveraging the affordances offered by articulated tangible user interfaces and motion capture retargeting solutions. To this aim, orientations of an instrumented prop are recorded together with animator's motion in the 3D space and used to quickly pose characters in the virtual environment...
April 3, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28388456/women-s-experiences-of-labour-and-birth-when-having-a-termination-of-pregnancy-for-fetal-abnormality-in-the-second-trimester-of-pregnancy-a-qualitative-meta-synthesis
#17
Kay Jones, Kathleen Baird, Jenny Fenwick
OBJECTIVE: to explore women's experiences of labour and birth in the context of a termination of pregnancy for fetal abnormality in the second trimester of pregnancy. DESIGN: meta-synthesis of 10 qualitative studies which included the experiences of 581 women. Data analysis was informed by van Manen's four lifeworld existentials (lived body, lived space, lived time and lived human relationships) and focused only on women's experiences of their labour and birth when terminating a pregnancy in the second trimester for fetal abnormality...
March 28, 2017: Midwifery
https://www.readbyqxmd.com/read/28385912/translating-concerns-into-action-a-detailed-qualitative-evaluation-of-an-interdisciplinary-intervention-on-medical-wards
#18
Samuel Pannick, Stephanie Archer, Maximillian J Johnston, Iain Beveridge, Susannah Jane Long, Thanos Athanasiou, Nick Sevdalis
OBJECTIVES: To understand how frontline reports of day-to-day care failings might be better translated into improvement. DESIGN: Qualitative evaluation of an interdisciplinary team intervention capitalising on the frontline experience of care delivery. Prospective clinical team surveillance (PCTS) involved structured interdisciplinary briefings to capture challenges in care delivery, facilitated organisational escalation of the issues they identified, and feedback...
April 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28384216/three-dimensional-reconstruction-of-highly-complex-microscopic-samples-using-scanning-electron-microscopy-and-optical-flow-estimation
#19
Ahmadreza Baghaie, Ahmad Pahlavan Tafti, Heather A Owen, Roshan M D'Souza, Zeyun Yu
Scanning Electron Microscope (SEM) as one of the major research and industrial equipment for imaging of micro-scale samples and surfaces has gained extensive attention from its emerge. However, the acquired micrographs still remain two-dimensional (2D). In the current work a novel and highly accurate approach is proposed to recover the hidden third-dimension by use of multi-view image acquisition of the microscopic samples combined with pre/post-processing steps including sparse feature-based stereo rectification, nonlocal-based optical flow estimation for dense matching and finally depth estimation...
2017: PloS One
https://www.readbyqxmd.com/read/28377836/scientific-publication-performance-of-turkish-anaesthesia-clinics-in-high-impact-factor-international-journals-between-2005-and-2014-a-bibliometric-analysis
#20
Hüseyin Oğuz Yılmaz, Rovnat Babazade, Oğuz Alp Turan, Betül Babazade, Onur Koyuncu, Alparslan Turan
OBJECTIVE: International scientific publication productivity is a tangible indicator for the accuracy of scientific policies. The quality of scientific publications is not increasing despite the fast increase in the publication count in Turkey. The international publication activities of Turkish anaesthesia clinics have not been previously explored. Thus, we aimed to evaluate the high quality scientific productivity of Turkish anesthesia clinics within the last 10 years. METHODS: We searched for studies conducted by anaesthesiologists in Turkey within the last 10 years and published in journals listed under the medical subject categories of anaesthesiology and critical care using 'Thomson Reuters InCites' and PubMed databases...
February 2017: Turkish Journal of Anaesthesiology and Reanimation
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