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https://www.readbyqxmd.com/read/28532179/capturing-context-related-change-in-emotional-dynamics-via-fixed-moderated-time-series-analysis
#1
Janne K Adolf, Manuel C Voelkle, Annette Brose, Florian Schmiedek
Much of recent affect research relies on intensive longitudinal studies to assess daily emotional experiences. The resulting data are analyzed with dynamic models to capture regulatory processes involved in emotional functioning. Daily contexts, however, are commonly ignored. This may not only result in biased parameter estimates and wrong conclusions, but also ignores the opportunity to investigate contextual effects on emotional dynamics. With fixed moderated time series analysis, we present an approach that resolves this problem by estimating context-dependent change in dynamic parameters in single-subject time series models...
May 22, 2017: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/28503651/effect-of-play-based-occupational-therapy-on-symptoms-of-hospitalized-children-with-cancer-a-single-subject-study
#2
Ahmad Mohammadi, Afsoon Hassani Mehraban, Shahla A Damavandi
OBJECTIVE: Cancer is one of the four leading causes of death in children. Its courses of diagnosis and treatment can cause physiologic symptoms and psychological distress that secondarily affect children's quality of life and participation in daily activities. The aim of this study was to investigate the effect of play-based occupational therapy on pain, anxiety, and fatigue in hospitalized children with cancer who were receiving chemotherapy. METHODS: Two hospitalized children with acute lymphoblastic leukemia at least 4 months after diagnoses who received two courses of chemotherapy participated in this pilot study...
April 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28498732/early-writing-intervention
#3
Kristen L McMaster, Amy Kunkel, Jaehyun Shin, Pyung-Gang Jung, Erica Lembke
The purpose of this best evidence synthesis was to identify promising interventions that align with a theoretical model of early writing development, targeting three components of early writing: transcription, text generation, and self-regulation. We determined the extent to which these interventions are effective for children who struggle with early writing skills, by calculating effect sizes for group and single-subject designs, and we examined the overall quality of the research. Twenty-five studies met inclusion criteria...
May 1, 2017: Journal of Learning Disabilities
https://www.readbyqxmd.com/read/28496422/systematic-observation-of-an-expert-driver-s-gaze-strategy-an-on-road-case-study
#4
Otto Lappi, Paavo Rinkkala, Jami Pekkanen
In this paper we present and qualitatively analyze an expert driver's gaze behavior in natural driving on a real road, with no specific experimental task or instruction. Previous eye tracking research on naturalistic tasks has revealed recurring patterns of gaze behavior that are surprisingly regular and repeatable. Lappi (2016) identified in the literature seven "qualitative laws of gaze behavior in the wild": recurring patterns that tend to go together, the more so the more naturalistic the setting, all of them expected in extended sequences of fully naturalistic behavior...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28495369/group-level-spatio-temporal-pattern-recovery-in-meg-decoding-using-multi-task-joint-feature-learning
#5
Seyed Mostafa Kia, Fabian Pedregosa, Anna Blumenthal, Andrea Passerini
BACKGROUND: The use of machine learning models to discriminate between patterns of neural activity has become in recent years a standard analysis approach in neuroimaging studies. Whenever these models are linear, the estimated parameters can be visualized in the form of brain maps which can aid in understanding how brain activity in space and time underlies a cognitive function. However, the recovered brain maps often suffer from lack of interpretability, especially in group analysis of multi-subject data...
May 8, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28479342/normalizing-data-from-gaba-edited-mega-press-implementations-at-3-tesla
#6
Ashley D Harris, Nicolaas A J Puts, S Andrea Wijtenburg, Laura M Rowland, Mark Mikkelsen, Peter B Barker, C John Evans, Richard A E Edden
Standardization of results is an important milestone in the maturation of any truly quantitative methodology. For instance, a lack of measurement agreement across imaging platforms limits multisite studies, between-study comparisons based on the literature, and inferences based on and the generalizability of results. In GABA-edited MEGA-PRESS, two key sources of differences between implementations are: differences in editing efficiency of GABA and the degree of co-editing of macromolecules (MM). In this work, GABA editing efficiency κ and MM-co-editing μ constants are determined for three widely used MEGA-PRESS implementations (on the most common MRI platforms; GE, Philips, and Siemens) by phantom experiments...
May 4, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28476663/a-probabilistic-template-of-human-mesopontine-tegmental-nuclei-from-in-vivo-7-t-mri
#7
REVIEW
Marta Bianciardi, Christian Strong, Nicola Toschi, Brian L Edlow, Bruce Fischl, Emery N Brown, Bruce R Rosen, Lawrence L Wald
Mesopontine tegmental nuclei such as the cuneiform, pedunculotegmental, oral pontine reticular, paramedian raphe and caudal linear raphe nuclei, are deep brain structures involved in arousal and motor function. Dysfunction of these nuclei is implicated in the pathogenesis of disorders of consciousness and sleep, as well as in neurodegenerative diseases. However, their localization in conventional neuroimages of living humans is difficult due to limited image sensitivity and contrast, and a stereotaxic probabilistic neuroimaging template of these nuclei in humans does not exist...
May 2, 2017: NeuroImage
https://www.readbyqxmd.com/read/28475253/vi-person-specific-individual-difference-approaches-in-developmental-research
#8
Michael J Rovine, Lawrence L Lo
In this chapter, we demonstrate the way certain common analytic approaches (e.g., polynomial curve modeling, repeated measures ANOVA, latent curve, and other factor models) create individual difference measures based on a common underlying model. After showing that these approaches require only means and covariance (or correlation) matrices to estimate regression coefficients based on a hypothesized model, we describe how to recast these models based on time-series related approaches focusing on single subject time series approaches (e...
June 2017: Monographs of the Society for Research in Child Development
https://www.readbyqxmd.com/read/28461062/analysis-strategies-for-high-resolution-uhf-fmri-data
#9
Jonathan R Polimeni, Ville Renvall, Natalia Zaretskaya, Bruce Fischl
Functional MRI (fMRI) benefits from both increased sensitivity and specificity with increasing magnetic field strength, making it a key application for Ultra-High Field (UHF) MRI scanners. Most UHF-fMRI studies utilize the dramatic increases in sensitivity and specificity to acquire high-resolution data reaching sub-millimeter scales, which enable new classes of experiments to probe the functional organization of the human brain. This review article surveys advanced data analysis strategies developed for high-resolution fMRI at UHF...
April 29, 2017: NeuroImage
https://www.readbyqxmd.com/read/28461058/a-population-mri-brain-template-and-analysis-tools-for-the-macaque
#10
REVIEW
Jakob Seidlitz, Caleb Sponheim, Daniel Glen, Frank Q Ye, Kadharbatcha S Saleem, David A Leopold, Leslie Ungerleider, Adam Messinger
The use of standard anatomical templates is common in human neuroimaging, as it facilitates data analysis and comparison across subjects and studies. For non-human primates, previous in vivo templates have lacked sufficient contrast to reliably validate known anatomical brain regions and have not provided tools for automated single-subject processing. Here we present the "National Institute of Mental Health Macaque Template", or NMT for short. The NMT is a high-resolution in vivo MRI template of the average macaque brain generated from 31 subjects, as well as a neuroimaging tool for improved data analysis and visualization...
April 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/28460270/demonstrating-treatment-efficacy-using-the-single-subject-randomization-design-a-tutorial-and-demonstration
#11
Susan Rvachew, Tanya Matthews
Single case research refers to the broader category of research designs in which each case serves as his or her own control. A single subject randomization design is a specific form in which sessions are randomly allocated to treatment conditions within subjects. Two tutorials on the application of these designs are provided. In the single subject randomized phase design, baseline probes are administered repeatedly during a no-treatment or usual care phase; subsequently probes are administered repeatedly during the treatment phase of the experiment; the starting point for the treatment phase is determined by random selection...
April 22, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28454998/finite-element-analysis-of-the-biomechanical-effects-of-3-posterolateral-corner-reconstruction-techniques-for-the-knee-joint
#12
Kyoung-Tak Kang, Yong-Gon Koh, Juhyun Son, Sung-Jae Kim, Sungryul Choi, Moonki Jung, Sung-Hwan Kim
PURPOSE: To compare the forces exerted on the cruciate ligaments and the contact stresses on the tibiofemoral (TF) and patellofemoral (PF) joints with respect to 3 different tibial- and fibular-based posterolateral corner (PLC) reconstructions under dynamic loading conditions. METHODS: A subject-specific finite element knee model was developed by using 3-dimensional anatomic data from motion captures in gait and squat activities, including in vivo knee joint kinematics and muscle forces for the single subject...
April 25, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28448430/family-dog-assisted-adapted-physical-activity-a-case-study
#13
Amanda Tepfer, Samantha Ross, Megan MacDonald, Monique A R Udell, Craig Ruaux, Wendy Baltzer
Purpose: The aim of this case study was to examine the individual effects of an adapted physical activity, animal-assisted intervention (APA-AAI) with the family dog on motor skills, physical activity, and quality of life of a child with cerebral palsy (CP). Method: This study used an A-B-A single-subject design. The assessment phase (phase A) occurred pre- and post-intervention. This consisted of standardized assessments of motor skills, quality of life questionnaires, physical activity (measured using the GT3X+ accelerometer) and the human-animal bond...
April 27, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28444975/dissociation-between-the-neural-correlates-of-conscious-face-perception-and-visual-attention
#14
Joaquin Navajas, Aleksander W Nitka, Rodrigo Quian Quiroga
Given the higher chance to recognize attended compared to unattended stimuli, the specific neural correlates of these two processes, attention and awareness, tend to be intermingled in experimental designs. In this study, we dissociated the neural correlates of conscious face perception from the effects of visual attention. To do this, we presented faces at the threshold of awareness and manipulated attention through the use of exogenous prestimulus cues. We show that the N170 component, a scalp EEG marker of face perception, was modulated independently by attention and by awareness...
April 26, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28438712/empirical-consideration-of-the-effects-of-acquisition-parameters-and-analysis-model-on-clinically-feasible-q-ball-imaging
#15
Kurt G Schilling, Vishwesh Nath, Justin A Blaber, Prasanna Parvathaneni, Adam W Anderson, Bennett A Landman
Q-ball imaging (QBI) is a popular high angular resolution diffusion imaging (HARDI) technique used to study brain architecture in vivo. Simulation and phantom-based studies suggest that QBI results are affected by the b-value, the number of diffusion weighting directions, and the signal-to-noise ratio (SNR). However, optimal acquisition schemes for QBI in clinical settings are largely undetermined given empirical (observed) imaging considerations. In this study, we acquire a HARDI dataset at five b-values with 11 repetitions on a single subject to investigate the effects of acquisition scheme and subsequent analysis models on the accuracy and precision of measures of tissue composition and fiber orientation derived from clinically feasible QBI at 3T...
April 24, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28432780/single-subject-independent-component-analysis-based-intensity-normalization-in-non-quantitative-multi-modal-structural-mri
#16
Sebastian Papazoglou, Jens Würfel, Friedemann Paul, Alexander U Brandt, Michael Scheel
Non-quantitative MRI is prone to intersubject intensity variation rendering signal intensity level based analyses limited. Here, we propose a method that fuses non-quantitative routine T1-weighted (T1w), T2w, and T2w fluid-saturated inversion recovery sequences using independent component analysis and validate it on age and sex matched healthy controls. The proposed method leads to consistent and independent components with a significantly reduced coefficient-of-variation across subjects, suggesting potential to serve as automatic intensity normalization and thus to enhance the power of intensity based statistical analyses...
April 22, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28410582/metronidazole-for-the-treatment-of-tritrichomonas-foetus-in-bulls
#17
David Love, Virginia R Fajt, Thomas Hairgrove, Meredyth Jones, James A Thompson
BACKGROUND: Tritrichomonas foetus is a sexually transmitted protozoon that causes reproductive failure, among cattle, so disruptive that many western US states have initiated control programs. Current control programs are based on the testing and exclusion of individual bulls. Unfortunately, these programs are utilizing screening tests that are lacking in sensitivity. Blanket treatment of all the exposed bulls and adequate sexual rest for the exposed cows could provide a more viable disease control option...
April 14, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28407310/totally-implantable-hearing-system-five-year-hearing-results
#18
Jack A Shohet, Eric M Kraus, Peter J Catalano, Elizabeth Toh
OBJECTIVES/HYPOTHESIS: 1) To provide long-term hearing outcome measures of a totally implantable hearing system (implant) and compare to the baseline unaided (BLU) and baseline aided (BLA) conditions, and 2) discuss relevant safety measures. STUDY DESIGN: Prospective, nonrandomized, multicenter, single-subject-as-own-control design. METHODS: Fifty-one subjects with mild to severe sensorineural hearing loss were implanted between 2008 and 2009 and enrolled in this postmarket approval study in the setting of private and hospital-based practices...
April 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28402539/associating-resting-state-connectivity-with-trait-impulsivity
#19
Nicholas H Angelides, Jayesh Gupta, Timothy J Vickery
Psychometric research has identified stable traits that predict inter-individual differences in appetitive motivation and approach behavior. Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales have been developed to quantitatively assess these traits. However, neural mechanisms corresponding to the proposed constructs reflected in BIS/BAS are still poorly defined. The ventral striatum (VS) and orbitofrontal cortex (OFC) are implicated in subserving reward-related functions that are also associated with the BAS...
April 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28393373/a-population-based-approach-to-analyzing-pulses-in-time-series-of-hormone-data
#20
K W Horton, N E Carlson, G K Grunwald, M J Mulvahill, A J Polotsky
Studies of reproductive physiology involve rapid sampling protocols that result in time series of hormone concentrations. The signature pattern in these times series is pulses of hormone release. Various statistical models for quantifying the pulsatile release features exist. Currently these models are fitted separately to each individual and the resulting estimates averaged to arrive at post hoc population-level estimates. When the signal-to-noise ratio is small or the time of observation is short (e.g., 6 h), this two-stage estimation approach can fail...
April 9, 2017: Statistics in Medicine
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