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https://www.readbyqxmd.com/read/28337148/on-the-estimation-accuracy-of-the-3d-body-center-of-mass-trajectory-during-human-locomotion-inverse-vs-forward-dynamics
#1
Gaspare Pavei, Elena Seminati, Dario Cazzola, Alberto E Minetti
The dynamics of body center of mass (BCoM) 3D trajectory during locomotion is crucial to the mechanical understanding of the different gaits. Forward Dynamics (FD) obtains BCoM motion from ground reaction forces while Inverse Dynamics (ID) estimates BCoM position and speed from motion capture of body segments. These two techniques are widely used by the literature on the estimation of BCoM. Despite the specific pros and cons of both methods, FD is less biased and considered as the golden standard, while ID estimates strongly depend on the segmental model adopted to schematically represent the moving body...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28330464/spectral-temporal-eeg-dynamics-of-speech-discrimination-processing-in-infants-during-sleep
#2
Phillip M Gilley, Kristin Uhler, Kaylee Watson, Christine Yoshinaga-Itano
BACKGROUND: Oddball paradigms are frequently used to study auditory discrimination by comparing event-related potential (ERP) responses from a standard, high probability sound and to a deviant, low probability sound. Previous research has established that such paradigms, such as the mismatch response or mismatch negativity, are useful for examining auditory processes in young children and infants across various sleep and attention states. The extent to which oddball ERP responses may reflect subtle discrimination effects, such as speech discrimination, is largely unknown, especially in infants that have not yet acquired speech and language...
March 22, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28317719/effect-of-a-multiple-freeze-thaw-process-on-structural-and-foaming-properties-of-individual-egg-white-proteins
#3
Xiang Duan, Junyi Li, Qinjun Zhang, Tong Zhao, Mei Li, Xueming Xu, Xuebo Liu
In this study, major albumen proteins (ovalbumin, ovomucoid, ovotransferrin, lysozyme and ovomucin) were singly subjected to a multiple freeze-thaw process, and the resulting changes in structural characteristics and foamability were investigated. Structural changes of proteins occurred during the process, regarding by sulfhydryl-disulfide interchange and exposure of hydrophobic groups. The differential scanning calorimetry and scanning electron microscopy showed that these albumen proteins underwent denaturation, dissociation and possibly aggregation...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28293468/a-method-for-independent-component-graph-analysis-of-resting-state-fmri
#4
Demetrius Ribeiro de Paula, Erik Ziegler, Pubuditha M Abeyasinghe, Tushar K Das, Carlo Cavaliere, Marco Aiello, Lizette Heine, Carol di Perri, Athena Demertzi, Quentin Noirhomme, Vanessa Charland-Verville, Audrey Vanhaudenhuyse, Johan Stender, Francisco Gomez, Jean-Flory L Tshibanda, Steven Laureys, Adrian M Owen, Andrea Soddu
INTRODUCTION: Independent component analysis (ICA) has been extensively used for reducing task-free BOLD fMRI recordings into spatial maps and their associated time-courses. The spatially identified independent components can be considered as intrinsic connectivity networks (ICNs) of non-contiguous regions. To date, the spatial patterns of the networks have been analyzed with techniques developed for volumetric data. OBJECTIVE: Here, we detail a graph building technique that allows these ICNs to be analyzed with graph theory...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28287369/analyzing-the-effects-of-different-signs-to-increase-the-availability-of-designated-van-accessible-parking-spaces
#5
E Zhang, Glen W White
Often, designated van accessible parking spaces are occupied by non-ramp or lift equipped vehicles (NRLEV) with accessible parking permits. This causes inconvenience, safety concerns, and reduced availability of parking spaces for ramp or lift equipped vehicles (RLEV). The researchers conducted a single subject design study with two settings to examine a differential comparison between the standard van sign versus intervention signs (pictorial representation of a ramp-equipped van plus messages) to determine which is more effective to signal NRLEV users not to park in designated van accessible spaces...
April 2017: Journal of Prevention & Intervention in the Community
https://www.readbyqxmd.com/read/28270790/consistently-showing-your-best-side-intra-individual-consistency-in-selfie-pose-orientation
#6
Annukka K Lindell
Painted and photographic portraits of others show an asymmetric bias: people favor their left cheek. Both experimental and database studies confirm that the left cheek bias extends to selfies. To date all such selfie studies have been cross-sectional; whether individual selfie-takers tend to consistently favor the same pose orientation, or switch between multiple poses, remains to be determined. The present study thus examined intra-individual consistency in selfie pose orientations. Two hundred selfie-taking participants (100 male and 100 female) were identified by searching #selfie on Instagram...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28252520/therapeutic-effects-of-horseback-riding-interventions-a-systematic-review-and-meta-analysis
#7
Alexandra Stergiou, Meropi Tzoufi, Evangelia Ntzani, Dimitrios Varvarousis, Alexandros Beris, Avraam Ploumis
OBJECTIVE: Equine-assisted therapies, such as therapeutic riding and hippotherapy, are believed to have positive physical and emotional effects in individuals with neuromotor, developmental, and physical disabilities. The purpose of this review was to determine whether therapeutic riding and hippotherapy improve balance, motor function, gait, muscle symmetry, pelvic movement, psychosocial parameters, and the patients' overall quality of life. DESIGN: In this study, a literature search was conducted on MEDLINE, CINAHL, MBASE, SportDiscus, Cochrane Database of Systematic Reviews, Cochrane Controlled Trials Register, PEDro, DARE, Google Scholar, and Dissertation Abstracts...
March 1, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28249758/gaussian-process-based-independent-analysis-for-temporal-source-separation-in-fmri
#8
Ditte Høvenhoff Hald, Ricardo Henao, Ole Winther
Functional Magnetic Resonance Imaging (fMRI) gives us a unique insight into the processes of the brain, and opens up for analyzing the functional activation patterns of the underlying sources. Task-inferred supervised learning with restrictive assumptions in the regression set-up, restricts the exploratory nature of the analysis. Fully unsupervised independent component analysis (ICA) algorithms, on the other hand, can struggle to detect clear classifiable components on single-subject data. We attribute this shortcoming to inadequate modeling of the fMRI source signals by failing to incorporate its temporal nature...
February 27, 2017: NeuroImage
https://www.readbyqxmd.com/read/28248612/health-related-quality-of-life-outcomes-following-adult-cochlear-implantation-a-prospective-cohort-study
#9
Douglas P Sladen, Ann Peterson, Matt Schmitt, Amy Olund, Katherine Teece, Brittany Dowling, Melissa DeJong, Alyce Breneman, Charles W Beatty, Matthew L Carlson, Brian A Neff, Becky Hughes-Borst, Colin L Driscoll
INTRODUCTION: The benefits of cochlear implantation extend beyond improved speech recognition and into overall health-related quality of life (HRQoL). Several measures of HRQoL, categorized as generic or disease specific, have been used in the cochlear implant literature. The clinical utility of generic HRQoL measures have been reported to be variable by previous investigators. The degree to which HRQoL correlates to speech perception is largely unknown. METHODS: A prospective single-subject design at a large tertiary care center...
March 1, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28244178/evaluation-of-an-optimized-18-f-fluoro-deoxy-glucose-positron-emission-tomography-voxel-wise-method-to-early-support-differential-diagnosis-in-atypical-parkinsonian-disorders
#10
S P Caminiti, P Alongi, L Majno, M A Volontè, C Cerami, L Gianolli, G Comi, D Perani
BACKGROUND AND PURPOSE: Atypical Parkinsonian disorders (APD) frequently overlap in clinical presentations, making the differential diagnosis challenging in the early stages. The present study aimed to evaluate the accuracy of the [(18) F]fluoro-deoxy-glucose positron emission tomography Statistical Parametric Mapping (SPM) optimized procedure in supporting the early and differential diagnosis of APD. METHODS: Seventy patients with possible APD were retrospectively included from a large clinical cohort...
February 28, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28243574/5-year-imaging-sequelae-of-concussive-blast-injury-and-relation-to-early-clinical-outcome
#11
Christine L Mac Donald, Jason Barber, Jalal Andre, Nicole Evans, Chris Panks, Samantha Sun, Kody Zalewski, R Elizabeth Sanders, Nancy Temkin
Current imaging diagnostic techniques are often insensitive to the underlying pathological changes following mild traumatic brain injury (TBI) or concussion so much so that the explicit definition of these uncomplicated mild brain injuries includes the absence of radiological findings. In the US military, this is complicated by the natural tendency of service members to down play symptoms for fear of removal from their unit particularly in combat making it challenging for clinicians to definitively diagnose and determine course of treatment...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28236099/a-meta-analysis-of-single-subject-research-on-behavioral-momentum-to-enhance-success-in-students-with-autism
#12
Richard J Cowan, Leah Abel, Lindsay Candel
We conducted a meta-analysis of single-subject research studies investigating the effectiveness of antecedent strategies grounded in behavioral momentum for improving compliance and on-task performance for students with autism. First, we assessed the research rigor of those studies meeting our inclusionary criteria. Next, in order to apply a universal metric to help determine the effectiveness of this category of antecedent strategies investigated via single-subject research methods, we calculated effect sizes via omnibus improvement rate differences (IRDs)...
February 24, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28230599/a-targeted-next-generation-genetic-sequencing-study-on-tetralogy-of-fallot-combined-with-cleft-lip-and-palate
#13
Lin Liu, Haisong Bu, Yifeng Yang, Zhiping Tan, Fei Zhang, Shijun Hu, Tianli Zhao
BACKGROUND: Congenital heart disease (CHD), plus cleft lip and palate (CLP) are currently the most common types of structural malformation in infants. Many genes have been investigated for their involvement in CHD with CLP. Targeted next-generation sequencing can analyze large amounts of genetic information rapidly, and thus address this question. METHODS: The authors designed a targeted, next-generation sequencing gene panel for 455 genes previously implicated in CHD or CLP...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28229348/brief-report-using-ipads-for-self-monitoring-of-students-with-autism
#14
Joy F Xin, Mary E Sheppard, Michelle Brown
This study examined the effect of using an iPad for students with autism spectrum disorder (ASD) on self-monitoring their behaviors in class. Four students with ASD were taught on-task behaviors by watching self-modeled video saved in the application "Choiceworks" on their iPads, and collected data on their own behaviors. A single subject research design with ABAB phases was used. Student behaviors were observed using interval recording and behavioral occurrences were compared across phases. Results showed that the participating students' on-task behaviors (e...
February 22, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28224606/single-subject-research-designs-in-pediatric-rehabilitation-a-valuable-step-towards-knowledge-translation
#15
REVIEW
Lynne Romeiser-Logan, Rebecca Slaughter, Robbin Hickman
Knowledge translation may be particularly challenging in pediatric rehabilitation, where study findings are often ambiguous owing to low statistical power or inconsistent responses to intervention. Disconnection between research protocols and clinical practicality, as well as variability of responsiveness in heterogeneous pediatric populations, may further impede integration of research findings into everyday practice. Use of single-subject research designs (SSRDs) may bridge the gap between research and practice, with robust design options that better identify and preserve patterns of responsiveness to specific interventions and offer protocols that are more readily implemented in practice settings than can be done in traditional randomized controlled trials...
February 22, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28210066/effects-of-interactive-metronome-training-on-postural-stability-and-upper-extremity-function-in-parkinson-s-disease-a-case-study
#16
Arim Kim, Hye-Sun Lee, Chiang-Soon Song
[Purpose] The purpose of this study was to examine the effects of interactive metronome training on the postural stability and upper extremity function of an individual with Parkinson's disease. [Subject and Methods] The participant of this case study was a 75-year-old female with Parkinson's disease diagnosed 7 years prior. This study was a single-subject research with an A-B-A design. She received IM training during the treatment phase (B phase) for 40 minutes per session. She was assessed pretest and posttest using the Berg balance scale and Wolf motor function test, and at baseline and the treatment phase using the measured box-and-block test and a Tetrax system...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28188914/connectivity-based-parcellation-reveals-distinct-cortico-striatal-connectivity-fingerprints-in-autism-spectrum-disorder
#17
Joshua H Balsters, Dante Mantini, Nicole Wenderoth
Autism Spectrum Disorder (ASD) has been associated with abnormal synaptic development causing a breakdown in functional connectivity. However, when measured at the macro scale using resting state fMRI, these alterations are subtle and often difficult to detect due to the large heterogeneity of the pathology. Recently, we outlined a novel approach for generating robust biomarkers of resting state functional magnetic resonance imaging (RS-fMRI) using connectivity based parcellation of gross morphological structures to improve single-subject reproducibility and generate more robust connectivity fingerprints...
February 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/28185628/use-of-bedside-abdominal-ultrasound-to-confirm-intestinal-motility-in-neonates-with-gastroschisis-a-feasibility-study
#18
Lori A Gurien, Deidre L Wyrick, Melvin S Dassinger, Jeffrey M Burford, Steven C Mehl, Marie E Saylors, Samuel D Smith
BACKGROUND: Optimal timing to begin feeds in neonates with gastroschisis remains unclear. We examined if bedside abdominal ultrasound for intestinal motility is a feasible tool to detect return of bowel function in neonates with gastroschisis. METHODS: Neonates born with uncomplicated gastroschisis who underwent closure received daily ultrasound exams. Full motility was defined as peristalsis seen in all quadrants. Average length of time between abdominal wall closure and start of enteral feeds, full ultrasound motility, and clinical characteristics was compared using Student's t-tests...
January 26, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28183990/human-dosimetry-of-the-nmda-receptor-ligand-11-c-gmom
#19
Jasper van der Aart, Thalia F van der Doef, Paul Horstman, Marc C Huisman, Robert C Schuit, Arthur van Lingen, Albert D Windhorst, Bart N M van Berckel, Adriaan A Lammertsma
The methylguanadine derivative [(11)C]GMOM has been used successfully to quantify N-methyl-D-aspartate (NMDA) receptor binding in humans. The purpose of the present study was to estimate the [(11)C]GMOM radiation dose in healthy humans. Methods: Following [(11)C]GMOM injection, three female and two male subjects underwent 10 consecutive whole body PET scans in approximately 77 minutes. 7 source organs were defined manually, scaled to a gender specific reference, and residence times were calculated for input into OLINDA/EXM software...
February 9, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28179553/mouth-and-voice-a-relationship-between-visual-and-auditory-preference-in-the-human-superior-temporal-sulcus
#20
Lin L Zhu, Michael S Beauchamp
Cortex in and around the human posterior superior temporal sulcus (pSTS) is known to be critical for speech perception. The pSTS responds to both the visual modality (especially biological motion) and the auditory modality (especially human voices). Using fMRI in single subjects with no spatial smoothing, we show that visual and auditory selectivity are linked. Regions of the pSTS were identified that preferred visually presented moving mouths (presented in isolation or as part of a whole face) or moving eyes...
March 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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