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https://www.readbyqxmd.com/read/29353438/examination-of-pituitary-adenylate-cyclase-activating-polypeptide-pacap-as-a-potential-biomarker-in-heart-failure-patients
#1
Zsolt Sarszegi, Dora Szabo, Balazs Gaszner, Attila Konyi, Dora Reglodi, Jozsef Nemeth, Beata Lelesz, Beata Polgar, Adel Jungling, Andrea Tamas
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic and multifunctional neuropeptide having neurotrophic, neuroprotective, and general cytoprotective actions in a variety of tissues based on its anti-apoptotic, anti-inflammatory, and antioxidant effects. Several studies have demonstrated its cardioprotective effects in vitro and in various animal models. However, few data are available on the presence of PACAP in human cardiac tissues and its role in the pathomechanism and progression of different cardiac disorders, particularly heart failure...
January 20, 2018: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/29353401/temporal-analysis-of-factors-associated-with-eat-10-in-outpatients-with-oropharyngeal-dysphagia-from-a-tertiary-care-clinic
#2
R S Bartlett, J E Moore, S L Thibeault
Self-perception of disease is increasingly recognized as a determinant of health. The Eating Assessment Tool-10 (EAT-10) is a functional health status questionnaire that measures the symptomatic severity of dysphagia from the patient's perspective. The objective of this work was to identify factors (demographics, clinical variables, swallowing physiology, health-related quality of life) associated with longitudinal change in EAT-10 scores in outpatients with oropharyngeal dysphagia at a multi-disciplinary, tertiary care clinic...
January 20, 2018: Dysphagia
https://www.readbyqxmd.com/read/29353392/a-preliminary-survey-on-prevalence-and-knowledge-about-different-aspects-of-somnambulism-in-buner-district-of-khyber-pakhtunkhwa-pakistan
#3
Wajiha, Zaigham Hasan, Rabia Afridi, Lubna Rahman, Naveeda Akhtar Qureshi, Kausar Saeed, Humera Afridi
PURPOSE: Present study was aimed to investigate the prevalence and knowledge about different aspects of somnambulism in general population of Buner District, KP, Pakistan, during December 2015-November 2016. METHODS: Data was collected through convenient sampling technique which was comprised of structured and detailed questionnaire. Collected data regarding different actions performed by sleepwalkers were adjusted through a weighted variable to generalize results...
January 20, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29353357/heath-risk-among-pesticide-sellers-in-bamenda-cameroon-and-peripheral-areas
#4
Jean Sonchieu, Edouard Nantia Akono, Cheche Tanwi Ngwamitang, Benoït Martin Ngassoum
In Bamenda and peripheral zones, studies have been focused on the effects of pesticides on farmers (pesticide users) while nothing has been done to assess the exposure of sellers to pesticides. This study aimed at evaluating the exposure of pesticide sellers in the same area. Thirty-two questionnaires were administered to 32 pesticide sellers systematically selected, and chi-square was used for statistical analysis. From each shop, a respondent was chosen among the workers according to its daily time spent in the workplace...
January 20, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29353341/field-of-view-normalization-in-multi-site-brain-mri
#5
Yangming Ou, Lilla Zöllei, Xiao Da, Kallirroi Retzepi, Shawn N Murphy, Elizabeth R Gerstner, Bruce R Rosen, P Ellen Grant, Jayashree Kalpathy-Cramer, Randy L Gollub
Multi-site brain MRI analysis is needed in big data neuroimaging studies, but challenging. The challenges lie in almost every analysis step including skull stripping. The diversities in multi-site brain MR images make it difficult to tune parameters specific to subjects or imaging protocols. Alternatively, using constant parameter settings often leads to inaccurate, inconsistent and even failed skull stripping results. One reason is that images scanned at different sites, under different scanners or protocols, and/or by different technicians often have very different fields of view (FOVs)...
January 20, 2018: Neuroinformatics
https://www.readbyqxmd.com/read/29353313/general-solution-of-the-chemical-master-equation-and-modality-of-marginal-distributions-for-hierarchic-first-order-reaction-networks
#6
Matthias Reis, Justus A Kromer, Edda Klipp
Multimodality is a phenomenon which complicates the analysis of statistical data based exclusively on mean and variance. Here, we present criteria for multimodality in hierarchic first-order reaction networks, consisting of catalytic and splitting reactions. Those networks are characterized by independent and dependent subnetworks. First, we prove the general solvability of the Chemical Master Equation (CME) for this type of reaction network and thereby extend the class of solvable CME's. Our general solution is analytical in the sense that it allows for a detailed analysis of its statistical properties...
January 20, 2018: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/29353312/child-labour-and-health-a-systematic-review
#7
REVIEW
Brice Lionel Batomen Kuimi, Oduro Oppong-Nkrumah, Jay Kaufman, Jose Ignacio Nazif-Munoz, Arijit Nandi
OBJECTIVES: This study aimed to synthesise the available knowledge, identify unexplored areas and discuss general limits of the published evidence. We focused on outcomes commonly hypothesised to be affected by child labour: nutritional status, harmful exposures and injuries. METHODS: Four electronic databases (EMBASE, MEDLINE, Scopus, ISI Web of Science) were searched in November 2017. All articles published since 1996, without restrictions on language, were considered for inclusion...
January 20, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29353308/single-stage-autotrophic-nitrogen-removal-process-at-high-loading-rate-granular-reactor-performance-kinetics-and-microbial-characterization
#8
Feiyue Qian, Abebe Temesgen Gebreyesus, Jianfang Wang, Yaoliang Shen, Wenru Liu, Lulin Xie
For the possible highest performance of single-stage combined partial nitritation/anammox (PNA) process, a continuous complete-mix granular reactor was operated at progressively higher nitrogen loading rate. The variations in bacterial community structure of granules were also characterized using high-throughput pyrosequencing, to give a detail insight to the relationship between reactor performance and functional organism abundance within completely autotrophic nitrogen removal system. In 172 days of operation, a superior total nitrogen (TN) removal rate over 3...
January 20, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29353286/predictors-of-thrombocytopenia-after-self-expandable-transcatheter-aortic-valve-replacement-a-single-center-experience-from-china
#9
Qifeng Zhu, Xianbao Liu, Wei He, Yuxin He, Mengyao Tang, Yinghao Sun, Xiaobin Xu, Keda Shi, Huijia Kong, Jubo Jiang, Liangwei Chen, Jie Chen, Po Hu, Qiyuan Xu, Jianan Wang
OBJECTIVES: The importance of thrombocytopenia (TP) has been discussed previously. However, data are still limited, especially on predictors of TP. We sought to investigate predictors of TP after transcatheter aortic valve replacement (TAVR), in particular, clinically significant TP. METHODS: We reviewed a total of 123 consecutive patients undergoing TAVR in our medical center. They were stratified into 3 groups according to the nadir platelet count post-TAVR: no/mild TP, moderate TP, and severe TP...
January 20, 2018: Cardiology
https://www.readbyqxmd.com/read/29353283/association-between-dental-caries-and-bmi-in-children-a-systematic-review-and-meta-analysis
#10
Dongru Chen, Qinghui Zhi, Yan Zhou, Ye Tao, Liping Wu, Huancai Lin
Research on the association between dental caries and body mass index (BMI) in children has shown contradictory results; thus we aimed to examine the association between dental caries and the full range of BMI classes among children. We comprehensively searched PubMed, Embase, and the Cochrane Library for studies published prior to March 2017. Articles comparing dental caries among the full range of BMI classes for children below 18 years of both genders were included. Fourteen studies were eligible for this study...
January 20, 2018: Caries Research
https://www.readbyqxmd.com/read/29353281/the-effectiveness-of-dietary-approaches-to-stop-hypertension-diet-intervention-in-persons-with-arterial-hypertension-and-obesity-a-key-role-of-the-patients-personality-profile
#11
Alicja Kucharska, Mariusz Jaworski, Mariusz Panczyk, Magdalena Pilska, Danuta Gajewska, Joanna Niegowska
BACKGROUND/AIMS: Benefits resulting from weight loss and dietary approaches to stop hypertension (DASH) diet in the treatment of arterial hypertension led to a search for a better therapy that would include psychological factors. The present study aimed to assess the relationship between the personality traits included in the Big Five personality traits and the effectiveness of treatment for weight loss in patients with essential hypertension and excessive body weight. METHODS: The study involved 84 patients with essential hypertension, overweight or obesity, managed by a hypertensiologist...
January 19, 2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29353252/systematic-review-of-general-practice-end-of-life-symptom-control
#12
REVIEW
Geoffrey K Mitchell, Hugh E Senior, Claire L Johnson, Julia Fallon-Ferguson, Briony Williams, Leanne Monterosso, Joel J Rhee, Peta McVey, Matthew P Grant, Michèle Aubin, Harriet Tg Nwachukwu, Patsy M Yates
BACKGROUND: End of life care (EoLC) is a fundamental role of general practice, which will become more important as the population ages. It is essential that general practice's role and performance of at the end of life is understood in order to maximise the skills of the entire workforce. OBJECTIVE: To provide a comprehensive description of the role and performance of general practitioners (GPs) and general practice nurses (GPNs) in EoLC symptom control. METHOD: Systematic literature review of papers from 2000 to 2017 were sought from Medline, PsycINFO, Embase, Joanna Briggs Institute and Cochrane databases...
January 20, 2018: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/29353234/psychiatric-symptoms-in-preclinical-behavioural-variant-frontotemporal-dementia-in-mapt-mutation-carriers
#13
Gayathri Cheran, Hannah Silverman, Masood Manoochehri, Jill Goldman, Seonjoo Lee, Liwen Wu, Sarah Cines, Emer Fallon, Brendan Desmond Kelly, Diana Angelika Olszewska, Judith Heidebrink, Sarah Shair, Stephen Campbell, Henry Paulson, Timothy Lynch, Stephanie Cosentino, Edward D Huey
OBJECTIVE: To characterise psychiatric symptoms in preclinical and early behavioural-variant frontotemporal dementia (bvFTD), a neurodegenerative disorder whose symptoms overlap with and are often mistaken for psychiatric illness. METHODS: The present study reports findings from a systematic, global, prospective evaluation of psychiatric symptoms in 12 preclinical carriers of pathogenic MAPT mutations, not yet meeting bvFTD diagnostic criteria, and 46 familial non-carrier controls...
January 20, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29353226/high-neutrophil-to-lymphocyte-ratios-predict-intracranial-atherosclerosis-in-a-healthy-population
#14
Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Sang Hyuck Kim, Su-Min Jeong
BACKGROUND AND AIMS: Although atherosclerosis has been shown to be an inflammatory disease, intracranial atherosclerosis (ICAS) has not been well addressed. The purpose of this study was to evaluate the relationship between the neutrophil to lymphocyte ratio (NLR) and the presence of ICAS lesions in a generally healthy population. METHODS: A consecutive series of subjects, who voluntarily visited for health check-ups between January 2006 and December 2013, were selected...
January 5, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29353199/applicability-of-kd-for-modelling-dissolved-137cs-concentrations-in-fukushima-river-water-case-study-of-the-upstream-ota-river
#15
Kazuyuki Sakuma, Hideki Tsuji, Seiji Hayashi, Hironori Funaki, Alex Malins, Kazuya Yoshimura, Hiroshi Kurikami, Akihiro Kitamura, Kazuki Iijima, Masaaki Hosomi
A study is presented on the applicability of the distribution coefficient (Kd) absorption/desorption model to simulate dissolved 137Cs concentrations in Fukushima river water. The upstream Ota River basin was simulated using GEneral-purpose Terrestrial Fluid-flow Simulator (GETFLOWS) for the period 1 January 2014 to 31 December 2015. Good agreement was obtained between the simulations and observations on water and suspended sediment fluxes, and on particulate bound 137Cs concentrations under both base and high flow conditions...
January 17, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29353186/addictive-behaviors-social-and-psychosocial-factors-and-electronic-cigarette-use-among-adolescents-a-population-based-study
#16
M Lindström, M Rosvall
OBJECTIVES: The aim was to investigate associations between e-cigarette use and social and psychosocial factors and cigarette smoking, alcohol consumption, and narcotics use among adolescents attending 9th grade in primary school and 2nd grade in secondary school. STUDY DESIGN: Cross-sectional study. METHODS: The public health survey among adolescents in Scania in 2016 includes pupils in grades 9 and 2. The associations between e-cigarette use and lifestyle, social and psychosocial factors, and trust were investigated with logistic regressions...
January 17, 2018: Public Health
https://www.readbyqxmd.com/read/29353177/psychiatric-disorders-and-compliance-with-prenatal-care-a-10-year-retrospective-cohort-compared-to-controls
#17
Joseph Ben-Sheetrit, Liat Huller-Harari, Michal Rasner, Nehemia Magen, Nitsa Nacasch, Paz Toren
BACKGROUND: Inadequate prenatal care has been associated with adverse perinatal outcomes. We sought to compare compliance with prenatal care visits (PCV), oral glucose tolerance test (OGTT) and serum alfa-fetoprotein (aFP) in women with psychiatric disorders (PD) and healthy controls. METHODS: Subjects were 5395 women (1043 PD and 4352 controls), members of Clalit Health Services (Tel-Aviv district, Israel), who gave birth during 2004-2014. We used Generalized Estimating Equations with binary-logistic models, considering consecutive pregnancies as repeated measures with unbalanced design...
January 17, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29353146/case-study-as-a-means-of-evaluating-the-impact-of-early-years-leaders-steps-paths-and-routes
#18
Mark Hadfield, Michael Jopling
The paper argues that case study will need to play an increasingly important role in the evaluation of leadership development programmes as both formal and substantive theories of leadership place greater emphasis upon the role played by organizational context on leaders ability to bring about change. Prolonged engagement within a case study provides researchers with opportunities to capture the dynamics between leaders and their organisational contexts. However, adopting a case study approach is no substitute for inadequate theorization of the link between leadership approaches and leadership effects...
January 8, 2018: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29353134/knowledge-attitudes-and-practices-of-pregnant-women-in-martinique-in-the-immediate-aftermath-of-the-zika-virus-outbreak
#19
J Delet, A Cabié, S Merle, J-L Voluménie, A Monthieux
INTRODUCTION: The WHO and the HCSP recognize the Zika virus as a public health problem of international concern primarily because of the foetal risks. During the epidemic in Martinique, several modifications to the normal obstetrical follow-up were set up and information had to be delivered to pregnant women about these modifications, the attitudes to prevent infection and the signs motivating additional visits. The objective of our work was to evaluate the knowledge, attitudes and practices of pregnant women in Martinique about the risks associated with Zika infection during pregnancy in the immediate aftermath of the epidemic...
January 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29353133/maternal-serum-uric-acid-levels-and-blood-pressure-during-pregnancy-a-community-based-cohort-study
#20
Guoli Zhou, Claudia Holzman, Zhehui Luo, Claire Margerison
OBJECTIVE: Studies find both very low and high serum uric acid (UA) levels are related to oxidative stress and to conditions such as cardiovascular diseases and chronic kidney disease in the general population. Pregnancy studies have focused only on high maternal UA. In present study, we tested whether unusually high and low levels of maternal serum UA are associated with increases in blood pressure (BP) during pregnancy. STUDY DESIGN: The Pregnancy Outcomes and Community Health Study enrolled 3019 pregnant women between their 16th-27th week of pregnancy from 52 clinics in 5 Michigan communities (1998-2004)...
January 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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