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https://www.readbyqxmd.com/read/28436542/intercontinental-telehealth-coaching-of-therapists-to-improve-verbalizations-by-children-with-autism
#1
Ana Barkaia, Trevor F Stokes, Tamar Mikiashvili
This study examined the effects of intercontinental telehealth coaching on the mastery of therapists' skills and improvements in verbalizations by children with autism, testing whether telehealth can be a solution for underserved communities in developing countries such as Georgia-Sakartvelo in Eastern Europe. Three therapists delivering and three children with autism receiving early-intervention services from the nongovernmental organization Children of Georgia in Tbilisi participated. Experimenters provided coaching from Virginia, USA to therapists in Georgia-Sakartvelo...
April 24, 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/28406112/doctors-of-tomorrow-an-innovative-curriculum-connecting-underrepresented-minority-high-school-students-to-medical-school
#2
Jordan Derck, Kate Zahn, Jonathan F Finks, Simanjit Mand, Gurjit Sandhu
BACKGROUND: Racial minorities continue to be underrepresented in medicine (URiM). Increasing provider diversity is an essential component of addressing disparity in health delivery and outcomes. The pool of students URiM that are competitive applicants to medical school is often limited early on by educational inequalities in primary and secondary schooling. A growing body of evidence recognizing the importance of diversifying health professions advances the need for medical schools to develop outreach collaborations with primary and secondary schools to attract URiMs...
September 2016: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/28376709/using-structural-knowledge-in-the-protein-data-bank-to-inform-the-search-for-potential-host-microbe-protein-interactions-in-sequence-space-application-to-mycobacterium-tuberculosis
#3
Gaurang Mahajan, Shekhar C Mande
BACKGROUND: A comprehensive map of the human-M. tuberculosis (MTB) protein interactome would help fill the gaps in our understanding of the disease, and computational prediction can aid and complement experimental studies towards this end. Several sequence-based in silico approaches tap the existing data on experimentally validated protein-protein interactions (PPIs); these PPIs serve as templates from which novel interactions between pathogen and host are inferred. Such comparative approaches typically make use of local sequence alignment, which, in the absence of structural details about the interfaces mediating the template interactions, could lead to incorrect inferences, particularly when multi-domain proteins are involved...
April 4, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28362785/step-scan-differential-fourier-transform-infrared-photoacoustic-spectroscopy-dftir-pas-a-spectral-deconvolution-method-for-weak-absorber-detection-in-the-presence-of-strongly-overlapping-background-absorptions
#4
Lixian Liu, Andreas Mandelis, Huiting Huan, Kirk H Michaelian
The determination of small absorption coefficients of trace gases in the atmosphere constitutes a challenge for analytical air contaminant measurements, especially in the presence of strongly absorbing backgrounds. A step-scan differential Fourier transform infrared photoacoustic spectroscopy (DFTIR-PAS) method was developed to suppress the coherent external noise and spurious photoacoustic (PA) signals caused by strongly absorbing backgrounds. The infrared absorption spectra of acetylene (C<sub>2</sub>H<sub>2</sub>) and local air were used to verify the performance of the step-scan DFTIR-PAS method...
April 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28360387/genetic-structure-of-pseudococcus-microcirculus-hemiptera-pseudococcidae-populations-on-epiphytic-orchids-in-south-florida
#5
J A Zettler, K Adams, B Frederick, A Gutting, N Ingebretsen, A Ragsdale, A Schrey
In 2012, the orchid mealy bug Pseudococcus microcirculus was first detected in situ in North America's more diverse orchid region, the Big Cypress Basin (Collier Co FL). A follow-up survey showed that the mealy bug is more widespread and found on epiphytic orchids in two locations, in both the Fakahatchee Strand State Preserve (sites B and F) and the Florida Panther National Wildlife Refuge (sites M and C). There, we collected mealy bugs (n = 54) from 35 orchid individuals and screened allelic variation at seven microsatellite loci...
March 2017: Journal of Genetics
https://www.readbyqxmd.com/read/28342314/electrochemical-dna-sandwich-biosensor-based-on-enzyme-amplified-microrna-21-detection-and-gold-nanoparticles
#6
Jihane Mandli, Hasna Mohammadi, Aziz Amine
In this work, a novel electrochemical biosensor for miRNA-21 determination, involving a sandwich hybridization assay onto gold nanoparticles modified pencil graphite electrode (PGE) and enzyme signal amplification was reported. The thiol terminated capture probe 1 (SH-P1) was immobilized on the electrode through AuS interaction. In the presence of target miRNA-21, SH-P1 hybridized with the first part of the target, however, the second part hybridizes with a biotinylated probe P2 (B-P2). Then, a streptavidin-conjugated alkaline phosphatase was immobilized by a specific binding of avidin-B-P2...
March 14, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/28330918/metabolic-rate-associates-with-but-does-not-generate-covariation-between-behaviours-in-western-stutter-trilling-crickets-gryllus-integer
#7
Indrikis A Krams, Petri T Niemelä, Giedrius Trakimas, Ronalds Krams, Gordon M Burghardt, Tatjana Krama, Aare Kuusik, Marika Mänd, Markus J Rantala, Raivo Mänd, Jukka Kekäläinen, Ilkka Sirkka, Severi Luoto, Raine Kortet
The causes and consequences of among-individual variation and covariation in behaviours are of substantial interest to behavioural ecology, but the proximate mechanisms underpinning this (co)variation are still unclear. Previous research suggests metabolic rate as a potential proximate mechanism to explain behavioural covariation. We measured the resting metabolic rate (RMR), boldness and exploration in western stutter-trilling crickets, Gryllus integer, selected differentially for short and fast development over two generations...
March 29, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28274575/relation-of-myocardial-contrast-enhanced-t1-mapping-by-cardiac-magnetic-resonance-to-left-ventricular-reverse-remodeling-after-cardiac-resynchronization-therapy-in-patients-with-nonischemic-cardiomyopathy
#8
Ulas Höke, Mand J H Khidir, Rob J van der Geest, Martin J Schalij, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan
Myocardial scar is known to be associated with limited left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse myocardial interstitial fibrosis, as assessed with myocardial T1 mapping cardiac magnetic resonance (CMR), has not been studied in patients with CRT. Therefore, we aimed at evaluating the association between diffuse myocardial interstitial fibrosis, in nonischemic cardiomyopathy patients, and LV reverse remodeling after CRT. A total of 40 patients (61 ± 11 years) with nonischemic cardiomyopathy who underwent CMR before CRT implantation were included...
May 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28249491/new-products
#9
Andreas Mandelis
In order to supplement manufacturers' information, this Department will welcome the submission by our readers of brief communications reporting measurements on the physical properties of materials which supersede earlier data or suggest new research applications.
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28231486/coded-excitation-waveform-engineering-for-high-frame-rate-synthetic-aperture-ultrasound-imaging
#10
Bahman Lashkari, Kaicheng Zhang, Edem Dovlo, Andreas Mandelis
Coded excitation was initially introduced to ultrasound imaging as a method for enhancing the signal-to-noise ratio (SNR). However, this method was also shown to be helpful in conjunction with synthetic aperture transmission for high frame rate imaging. Recently, we introduced two families of mismatched coded excitations based on frequency modulation chirp and combined frequency modulation and Golay code. Here "mismatched" indicates that the coded excitations generate very small cross-correlations among themselves while each has a very strong autocorrelation...
May 2017: Ultrasonics
https://www.readbyqxmd.com/read/28217309/qrs-duration-versus-morphology-and-survival-after-cardiac-resynchronization-therapy
#11
Mand J H Khidir, Victoria Delgado, Nina Ajmone Marsan, Martin J Schalij, Jeroen J Bax
AIMS: The prognostic implications of QRS duration and morphology in heart failure patients treated with cardiac resynchronization therapy (CRT) remains debated. The present evaluation investigated the association between QRS duration (<150 vs. ≥150 ms) and QRS morphology (left bundle brand block [LBBB] vs. non-LBBB) and long-term prognosis of a large cohort of unselected heart failure patients treated with CRT according to contemporary guidelines. METHODS AND RESULTS: Of 973 heart failure patients treated with CRT (mean age 66...
February 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28198891/photoacoustic-resonance-by-spatial-filtering-of-focused-ultrasound-transducers
#12
Dongyel Kang, Bahman Lashkari, Andreas Mandelis
The effect of a spherically focused ultrasound (US) transducer (TD) on photoacoustic (PA) measurements is analytically investigated using the concept of a virtual point detector. The derived analytical results indicate that the limited numerical aperture (NA) of the PA detector takes on the role of spatial filtering of the induced PA waves, which leads to the occurrence of a peak frequency in the PA spectrum. The mathematical description of this phenomenon is similar to the result of resonance peaks of light propagation in dielectrics...
February 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28179138/the-interdigitating-loop-of-the-enolase-superfamily-as-a-specificity-binding-determinant-or-flying-buttress
#13
REVIEW
Stephen L Bearne
BACKGROUND: Enzymes of the enolase superfamily (ENS) are mechanistically diverse, yet share a common partial reaction (abstraction of the α-proton from a carboxylate substrate). While the catalytic machinery responsible for the deprotonation reaction has been conserved, divergent evolution has led to numerous ENS members that catalyze different overall reactions. This rich functional diversity has made the ENS an excellent model system for developing the approaches necessary to validate enzyme function...
February 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28176418/impact-of-qrs-complex-duration-and-morphology-on-left-ventricular-reverse-remodelling-and-left-ventricular-function-improvement-after-cardiac-resynchronization-therapy
#14
Pieter van der Bijl, Mand Khidir, Melissa Leung, Bart Mertens, Nina Ajmone Marsan, Victoria Delgado, Jeroen J Bax
AIMS: To evaluate the impact of the interaction of QRS duration and morphology on left ventricular (LV) reverse remodelling and LV functional improvement in heart failure (HF) patients treated with cardiac resynchronization therapy (CRT). METHODS AND RESULTS: From an ongoing registry of HF patients treated with CRT according to contemporary guidelines, demographic, clinical, electrocardiographic (ECG) and echocardiographic characteristics were analysed. Patients were divided according to QRS duration and morphology: <150 ms vs...
February 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28147683/new-products
#15
Andreas Mandelis
No abstract text is available yet for this article.
January 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28128451/teaching-complex-verbal-operants-to-children-with-autism-and-establishing-generalization-using-the-peak-curriculum
#16
Mark R Dixon, Jacqueline Peach, Jacob H Daar, Cindy Penrod
The present study evaluated the feasibility of the PEAK Relational Training System's Generalization Module (Dixon, 2014b) to teach and establish generalization of autoclitic mands, distorted tacts, and creative path finding in three children diagnosed with autism spectrum disorder. Using a multiple-baseline design across behaviors, each participant was provided with differential reinforcement and a least-to-most prompting hierarchy for correct responses to a subset of stimuli, and responses to other similar stimulus sets were probed for emergent generalization...
January 27, 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/28113418/high-frame-rate-synthetic-aperture-ultrasound-imaging-using-mismatched-coded-excitation-waveform-engineering-a-feasibility-study
#17
Bahman Lashkari, Kaicheng Zhang, Andreas Mandelis
Mismatched coded excitation can be employed to increase the frame rate of synthetic aperture ultrasound imaging. The high auto-correlation and low cross-correlation of the transmitted signals enables the identification and separation of the signal sources at the receiver. Thus, the method provides B-mode imaging with simultaneous transmission from several elements and capability of spatial decoding of the transmitted signals which makes the imaging process equivalent to consecutive transmissions. Each transmission generates its own image and the combination of all the images results in a image with a high lateral resolution...
April 14, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28092684/biallelic-mutations-in-the-3-exonuclease-toe1-cause-pontocerebellar-hypoplasia-and-uncover-a-role-in-snrna-processing
#18
Rea M Lardelli, Ashleigh E Schaffer, Veerle R C Eggens, Maha S Zaki, Stephanie Grainger, Shashank Sathe, Eric L Van Nostrand, Zinayida Schlachetzki, Basak Rosti, Naiara Akizu, Eric Scott, Jennifer L Silhavy, Laura Dean Heckman, Rasim Ozgur Rosti, Esra Dikoglu, Anne Gregor, Alicia Guemez-Gamboa, Damir Musaev, Rohit Mande, Ari Widjaja, Tim L Shaw, Sebastian Markmiller, Isaac Marin-Valencia, Justin H Davies, Linda de Meirleir, Hulya Kayserili, Umut Altunoglu, Mary Louise Freckmann, Linda Warwick, David Chitayat, Susan Blaser, Ahmet Okay Çağlayan, Kaya Bilguvar, Huseyin Per, Christina Fagerberg, Henrik T Christesen, Maria Kibaek, Kimberly A Aldinger, David Manchester, Naomichi Matsumoto, Kazuhiro Muramatsu, Hirotomo Saitsu, Masaaki Shiina, Kazuhiro Ogata, Nicola Foulds, William B Dobyns, Neil C Chi, David Traver, Luigina Spaccini, Stefania Maria Bova, Stacey B Gabriel, Murat Gunel, Enza Maria Valente, Marie-Cecile Nassogne, Eric J Bennett, Gene W Yeo, Frank Baas, Jens Lykke-Andersen, Joseph G Gleeson
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals, consists of 12 Mg(2+)-dependent 3'-end RNases with substrate specificity that is mostly unknown. Pontocerebellar hypoplasia type 7 (PCH7) is a unique recessive syndrome characterized by neurodegeneration and ambiguous genitalia. We studied 12 human families with PCH7, uncovering biallelic, loss-of-function mutations in TOE1, which encodes an unconventional deadenylase...
March 2017: Nature Genetics
https://www.readbyqxmd.com/read/28086870/a-pilot-study-of-a-community-health-agent-led-type-2-diabetes-self-management-program-using-motivational-interviewing-based-approaches-in-a-public-primary-care-center-in-s%C3%A3-o-paulo-brazil
#19
Thais Moura Ribeiro do Valle Nascimento, Ken Resnicow, Marcia Nery, Alexandra Brentani, Elizabeth Kaselitz, Pooja Agrawal, Simanjit Mand, Michele Heisler
BACKGROUND: Rates of noncommunicable diseases (NCDs) such as type 2 diabetes are escalating in low and middle-income countries such as Brazil. Scalable primary care-based interventions are needed to improve self-management and clinical outcomes of adults with diabetes. This pilot study examines the feasibility, acceptability, and outcomes of training community health agents (CHAs) in Motivational Interviewing (MI)-based counseling for patients with poorly controlled diabetes in a primary care center in São Paulo, Brazil...
January 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28040907/new-products
#20
Andreas Mandelis
No abstract text is available yet for this article.
December 2016: Review of Scientific Instruments
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