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https://www.readbyqxmd.com/read/28340131/interobserver-variability-in-histologic-evaluation-of-liver-fibrosis-using-categorical-and-quantitative-scores
#1
Michael Pavlides, Jacqueline Birks, Eve Fryer, David Delaney, Nikita Sarania, Rajarshi Banerjee, Stefan Neubauer, Eleanor Barnes, Kenneth A Fleming, Lai Mun Wang
Objectives: The aim of the study was to investigate the interobserver agreement for categorical and quantitative scores of liver fibrosis. Methods: Sixty-five consecutive biopsy specimens from patients with mixed liver disease etiologies were assessed by three pathologists using the Ishak and nonalcoholic steatohepatitis Clinical Research Network (NASH CRN) scoring systems, and the fibrosis area (collagen proportionate area [CPA]) was estimated by visual inspection (visual-CPA)...
March 15, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28339886/optimal-method-of-measuring-the-t-peak-to-t-end-interval-for-risk-stratification-in-primary-prevention
#2
Todd M Rosenthal, Daniel Masvidal, Freddy M Abi Samra, Michael L Bernard, Sammy Khatib, Glenn M Polin, Paul A Rogers, Joel Q Xue, Daniel P Morin
Aims: Several published investigations demonstrated that a longer T-peak to T-end interval (Tpe) implies increased risk for ventricular tachyarrhythmia (VT/VF) and mortality. Tpe has been measured using diverse methods. We aimed to determine the optimal Tpe measurement method for screening purposes. Methods and results: We evaluated 305 patients with LVEF ≤ 35% and an implantable cardioverter-defibrillator implanted for primary prevention. Tpe was measured using seven different methods described in the literature, including six manual methods and the automated algorithm '12SL', and was corrected for heart rate...
February 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339289/the-role-of-delineation-education-programs-for-improving-interobserver-variability-in-target-volume-delineation-in-gastric-cancer
#3
Cem Onal, Mustafa Cengiz, Ozan Cem Guler, Yemliha Dolek, Serdar Ozkok
OBJECTIVE: To assess whether delineation courses for radiation oncologists improve interobserver variability in target volume delineation for postoperative gastric cancer radiotherapy planning. METHODS: Twenty-nine radiation oncologists delineated target volumes in a gastric cancer patient. An experienced radiation oncologist lectured about delineation based on contouring atlas and delineation recommendations. After course, the radiation oncologists provided delineation for the same patient blind to the previous delineation...
March 24, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28334616/comparison-of-mri-grading-for-cervical-neural-foraminal-stenosis-based-on-axial-and-oblique-sagittal-images-concordance-and-reliability-study
#4
Wooil Kim, Kyung-Sik Ahn, Chang Ho Kang, Woo Young Kang, Kyung-Sook Yang
The aim of this study was to assess the concordance between magnetic resonance imaging (MRI) grading for cervical neural foraminal stenosis (CNFS) based on axial and oblique sagittal images and evaluate the reliability of each grading plane. CNFS was graded at C2-3 to C7-T1 levels based on axial and oblique sagittal images separately by three radiologists. The concordance between CNFS grading based on axial and oblique sagittal images was strong for all three observers (Kendall's W=0.80, 0.79, and 0.82), despite the tendency of higher grading with oblique sagittal images...
March 15, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28334560/development-and-preliminary-testing-of-the-coordination-process-error-reporting-tool-cpert-a-prospective-clinical-surveillance-mechanism-for-teamwork-errors-in-the-pediatric-cardiac-icu
#5
Katherine E Bates, Judy A Shea, Geoffrey L Bird, Cynthia Field, Deipanjan Nandi, Robert E Shaddy, Joshua P Metlay
BACKGROUND: Patient safety reporting systems (PSRSs) may not detect teamwork or coordination process errors that affect all dimensions of quality defined by the Institute of Medicine. This study aimed to develop and observe the performance of a novel tool, the Coordination Process Error Reporting Tool (CPERT), as a prospective clinical surveillance mechanism for teamwork errors in the pediatric cardiac ICU. METHODS: Providers and parents used the qualitative nominal group technique to identify coordination process error examples...
December 2016: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28334054/lateral-cephalometric-analysis-for-treatment-planning-in-orthodontics-based-on-mri-compared-with-radiographs-a-feasibility-study-in-children-and-adolescents
#6
Alexander Heil, Eduardo Lazo Gonzalez, Tim Hilgenfeld, Philipp Kickingereder, Martin Bendszus, Sabine Heiland, Ann-Kathrin Ozga, Andreas Sommer, Christopher J Lux, Sebastian Zingler
OBJECTIVE: The objective of this prospective study was to evaluate whether magnetic resonance imaging (MRI) is equivalent to lateral cephalometric radiographs (LCR, "gold standard") in cephalometric analysis. METHODS: The applied MRI technique was optimized for short scanning time, high resolution, high contrast and geometric accuracy. Prior to orthodontic treatment, 20 patients (mean age ± SD, 13.95 years ± 5.34) received MRI and LCR. MRI datasets were postprocessed into lateral cephalograms...
2017: PloS One
https://www.readbyqxmd.com/read/28333782/the-normal-adult-human-internal-auditory-canal-a-volumetric-multidetector-computed-tomography-study
#7
Fahad Essbaiheen, Tarek Hegazi, Lorne Rosenbloom
OBJECTIVE: The purpose of this study was to demonstrate that volumetric analysis of multidetector computed tomography (CT) images can be used to calculate the volume of the adult human internal auditory canal (IAC) reproducibly, and to describe the range of normal IAC volumes in the adult population with subgroup analysis of sex, age, and laterality. BACKGROUND: Previous studies of the IAC have typically used measurements in two dimensions or by using casts of cadavers to measure IAC volumes...
March 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28333020/-18-f-choline-positron-emission-tomography-computed-tomography-and-multiparametric-magnetic-resonance-imaging-for-the-detection-of-early-local-recurrence-of-prostate-cancer-initially-treated-by-radiation-therapy-comparison-with-systematic-3-dimensional-transperineal
#8
Salim Kanoun, Paul Walker, Jean-Marc Vrigneaud, Edouard Depardon, Vincent Barbier, Olivier Humbert, Morgan Moulin, Gilles Créhange, Luc Cormier, Romaric Loffroy, François Brunotte, Alexandre Cochet
PURPOSE: To compare the diagnostic performance of (18)F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT), multiparametric prostate magnetic resonance imaging (mpMRI), and a combination of both techniques for the detection of local recurrence of prostate cancer initially treated by radiation therapy. METHODS AND MATERIALS: This was a retrospective, single-institution study of 32 patients with suspected prostate cancer recurrence who underwent both FCH-PET/CT and 3T mpMRI within 3 months of one another for the detection of recurrence...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28332866/comparing-cone-beam-computed-tomography-with-periapical-radiography-for-assessing-root-canal-obturation-in-vivo-using-microsurgical-findings-as-validation
#9
Dongzhe Song, Lan Zhang, Wei Zhou, Qinghua Zheng, Xingyu Duan, Xuedong Zhou, Dingming Huang
OBJECTIVES: The aim of this study was to verify whether there is a difference in the in vivo performance characteristics of CBCT and periapical radiography (PR) in assessing the apical extension of root canal obturation (RCO) and to evaluate the ability of CBCT in void detection using microsurgical findings as validation. METHODS: This study included 323 tooth roots that required surgical treatment and for which pre-existing periapical radiographs and CBCT images were available...
March 23, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28331942/contrast-enhanced-ultrasound-for-differentiating-benign-from-malignant-solid-small-renal-masses-comparison-with-contrast-enhanced-ct
#10
Shu-Ping Wei, Chao-Li Xu, Qing Zhang, Qi-Rui Zhang, Yan-E Zhao, Peng-Fei Huang, Ying-Dong Xie, Chang-Sheng Zhou, Fu-Li Tian, Bin Yang
PURPOSE: The study aimed to compare the diagnostic efficiency of contrast-enhanced ultrasound (CEUS) with that of contrast-enhanced computed tomography (CECT) in the evaluation of benign and malignant small renal masses (SRMs) (<4 cm) confirmed by pathology. METHODS: A total of 118 patients with 118 renal masses smaller than 4 cm diagnosed by both CEUS and CECT were enrolled in this study, including 25 benign lesions and 93 malignant lesions. All lesions were confirmed by histopathologic diagnosis after surgical resection...
March 22, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28329276/demonstration-of-infective-endocarditis-by-cardiac-ct-and-transoesophageal-echocardiography-comparison-with-intra-operative-findings
#11
Hyun Jung Koo, Dong Hyun Yang, Joon-Won Kang, Joo Yeon Lee, Dae-Hee Kim, Jong-Min Song, Duk-Hyun Kang, Jae-Kwan Song, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae-Won Lee, Tae-Hwan Lim
Aims: We aimed to compare imaging findings of infective endocarditis between computed tomography (CT) and transoesophageal echocardiography (TEE) using surgical inspection as a reference standard. Methods and results: Forty-nine patients (aged 54 ± 17 years, 69% men) who underwent pre-operative CT and TEE for infective endocarditis were included. Twelve of these patients had prosthetic valve endocarditis. Imaging findings of infective endocarditis were classified as vegetation, leaflet perforation, abscess/pseudoaneurysm, and paravalvular leakage...
February 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28327193/longitudinal-evaluation-of-aortic-hemodynamics-in-marfan-syndrome-new-insights-from-a-4d-flow-cardiovascular-magnetic-resonance-multi-year-follow-up-study
#12
Julia Geiger, Daniel Hirtler, Kristina Gottfried, Ozair Rahman, Emilie Bollache, Alex J Barker, Michael Markl, Brigitte Stiller
BACKGROUND: The aim of this 4D flow cardiovascular magnetic resonance (CMR) follow-up study was to investigate longitudinal changes in aortic hemodynamics in adolescent patients with Marfan syndrome (MFS). METHODS: 4D flow CMR for the assessment of in-vivo 3D blood flow with full coverage of the thoracic aorta was performed twice (baseline scan t1/follow-up scan t2) in 19 adolescent MFS patients (age at t1: 12.7 ± 3.6 years, t2: 16.2 ± 4.3 years) with a mean follow-up duration of 3...
March 22, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28325390/patterns-of-distribution-of-giant-congenital-melanocytic-nevi-gcmn-the-6b-rule
#13
Vanessa P Martins da Silva, Ashfaq Marghoob, Ramon Pigem, Cristina Carrera, Paula Aguilera, Joan A Puig-Butillé, Susana Puig, Josep Malvehy
BACKGROUND: Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN). OBJECTIVE: We sought to describe patterns of distribution of GCMN and propose a classification scheme. METHODS: Photographic records of patients with GCMN from the Hospital Clinic of Barcelona were analyzed and a classification based on observed GCMN distribution patterns was created. The classification was independently applied by 8 observers to cases found in the literature...
April 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28323693/assessment-of-vertebral-curves-using-the-manual-post-it-technique
#14
Brian P Gladnick, Joseph J Schreiber, Chad R Ishmael, Benjamin T Bjerke-Kroll, Matthew E Cunningham
STUDY DESIGN: A prospective study of a new technique. OBJECTIVE: The aims of this study were to report a manual technique for measuring vertebral curves on digital spine radiographs, and to assess the agreement of this technique with that of digital software for measuring vertebral curves. SUMMARY OF BACKGROUND DATA: Modern picture archiving and communication systems (PACS) typically include software for evaluating radiographic measurements...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323691/mri-may-serve-as-a-valid-alternative-to-standing-radiography-in-evaluating-the-sagittal-alignment-of-the-upper-thoracic-spine
#15
Fei Wang, Xu Sun, Saihu Mao, Zhen Liu, Jun Qiao, Feng Zhu, Zezhang Zhu, Tao Pan, Ling Chen, Qinghua Zhao, Yong Qiu
STUDY DESIGN: This study is of a retrospective radiographic design. OBJECTIVE: The objective of the study was to compare supine magnetic resonance images (MRI) with standing x-ray scanning in the evaluation of the sagittal alignment of the upper thoracic spine. SUMMARY OF BACKGROUND DATA: X-ray films have been reported to be inaccurate in evaluating the proximal thoracic sagittal alignment because of poor visibility of the upper thoracic region...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28322774/development-and-reliability-of-the-new-endoscopic-virtual-chromoendoscopy-score-the-picasso-score-paddington-international-virtual-chromoendoscopy-score-in-ulcerative-colitis
#16
Marietta Iacucci, Marco Daperno, Mark Lazarev, Razvan Arsenascu, Gian Eugenio Tontini, Oluseyi Akinola, Xianyong Sean Gui, Vincenzo Villanacci, Martin Goetz, Mark Lowerison, Brendan Cord Lethebe, Maurizio Vecchi, Helmut Neumann, Subrata Ghosh, Raf Bisschops, Ralf Kiesslich
INTRODUCTION: Endoscopic inflammation and healing are important therapeutic endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual chromoendoscopy (EVC) score that could reflect the full spectrum of mucosal and vascular changes including mucosal healing in UC. METHODS: Eight participants reviewed a 60-minute training module outlining the three different i-SCAN modes demonstrating the entire spectrum of inflammatory mucosal and vascular changes in UC...
March 16, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28319275/mrf-ann-a-machine-learning-approach-for-automated-er-scoring-of-breast-cancer-immunohistochemical-images
#17
T Mungle, S Tewary, D K DAS, I Arun, B Basak, S Agarwal, R Ahmed, S Chatterjee, C Chakraborty
Molecular pathology, especially immunohistochemistry, plays an important role in evaluating hormone receptor status along with diagnosis of breast cancer. Time-consumption and inter-/intraobserver variability are major hindrances for evaluating the receptor score. In view of this, the paper proposes an automated Allred Scoring methodology for estrogen receptor (ER). White balancing is used to normalize the colour image taking into consideration colour variation during staining in different labs. Markov random field model with expectation-maximization optimization is employed to segment the ER cells...
March 20, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28306635/ocular-fundus-photography-with-a-smartphone-device-in-acute-hypertension
#18
M Lorenza Muiesan, Massimo Salvetti, Anna Paini, Michela Riviera, Clara Pintossi, Fabio Bertacchini, Efrem Colonetti, Claudia Agabiti-Rosei, Maurizio Poli, Francesco Semeraro, Enrico Agabiti-Rosei, Andrea Russo
BACKGROUND: The ocular fundus examination is infrequently and poorly performed in the emergency department (ED) clinical settings, placing patients at risk for missed diagnosis of hypertensive emergencies. The aim of this study was to investigate the feasibility of the ocular fundus photography with a smartphone small optical device in an ED setting and to compare it with a traditional ocular fundus examination. METHODS: The study included 52 consecutive patients (mean age 69 ± 16 years, 50% women) presenting to a hospital ED with an acute increase in blood pressure (SBP > 180 and/or DBP > 100 mmHg)...
March 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28306208/evaluation-of-myocardial-microcirculation-using-intravoxel-incoherent-motion-imaging
#19
Anna Mou, Chen Zhang, Mengying Li, Fengqiang Jin, Qingwei Song, Ailian Liu, Zhiyong Li
PURPOSE: To explore whether cardiac magnetic resonance-intravoxel incoherent motion imaging (MR-IVIM) is feasible for the clinical evaluation of myocardial microcirculation. MATERIALS AND METHODS: The study included 30 patients (with hypertrophic cardiomyopathy, diabetes mellitus, hypertension, or combined diabetes and hypertension) and 34 healthy volunteers. MR-IVIM with a maximum gradient strength of 50 mT/m was performed on the left ventricular short axis (apex, middle, and base), using multiple b values (0-500 s/mm(2) ) on a 3...
March 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28304105/ultrasound-elastography-of-the-neonatal-brain-preliminary-study
#20
Hyun Gi Kim, Moon Sung Park, Jung-Dong Lee, Seon Young Park
OBJECTIVES: To determine the ultrasound elasticity of the brain in neonates METHODS: Strain elastography was performed in 21 healthy neonates (mean gestational age [GA], 34 weeks; range, 28-40 weeks). Elastographic scores were assigned to the following structures on a 5-point color scale (1-5): ventricle, periventricular white matter, caudate, subcortical, cortical gray matter, and subdural space. Three elastographic images were evaluated in each patient, and median elastographic scores were calculated...
March 17, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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