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https://www.readbyqxmd.com/read/28241666/iaoos-microlidar-on-buoy-development-and-first-atmospheric-observations-obtained-during-2014-and-2015-arctic-drifts
#1
Vincent Mariage, Jacques Pelon, Frédéric Blouzon, Stéphane Victori, Nicolas Geyskens, Nadir Amarouche, Christine Drezen, Antoine Guillot, Michel Calzas, Magali Garracio, Nicolas Wegmuller, Nathalie Sennéchael, Christine Provost
The in situ tests of first ever autonomous aerosol and cloud backscatter LIDAR (light detection and ranging) systems implemented on buoys for Arctic observations has been achieved in 2015 within the French EQUIPEX IAOOS project. The environmental and operational constraints were met by adopting a concept of a fibered microjoule lidar system using a laser diode. Two systems have been developed with and without polarization analysis capability. A specific optical design was used for polarization discrimination...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28241642/highly-sensitive-miniature-fluidic-flowmeter-based-on-an-fbg-heated-by-co-sup-2-sup-doped-fiber
#2
Zhengyong Liu, Lin Htein, Lun-Kai Cheng, Quincy Martina, Rob Jansen, Hwa-Yaw Tam
In this paper, we present a miniature fluidic flow sensor based on a short fiber Bragg grating inscribed in a single mode fiber and heated by Co<sup>2+</sup>-doped multimode fibers. The proposed flow sensor was employed to measure the flow rates of oil and water, showing good sensitivity of 0.339 nm/(m/s) and 0.578 nm/(m/s) for water and oil, flowing at v = 0.2 m/s. The sensitivity can be increased with higher laser power launched to the Co<sup>2+</sup>-doped multimode fibers. A small flow rate of 0...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28241588/colorimetric-discrimination-for-stokes-polarimetric-imaging
#3
Mingxuan Yu, Hesong Huang, Haofeng Hu, Lan Wu, Hongchen Zhai, Tiegen Liu
Traditional methods of discrimination for Stokes polarimetric imaging use grayscale images, in which the difference of the polarimetric properties is only reflected by the difference of grayscale. In this paper, we propose a method of colorimetric discrimination and classification for Stokes polarimetric imaging by the composed color polarimetric image, in which the objects with different polarization properties can appear in different colors. We show with real-world experiment that compared with the traditional method for the grayscale Stokes scalar image, the method proposed in this paper has a better performance for distinguishing objects with different polarization properties...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28241428/an-automated-micro-total-immunoassay-system-for-measuring-cancer-associated-%C3%AE-2-3-linked-sialyl-n-glycan-carrying-prostate-specific-antigen-may-improve-the-accuracy-of-prostate-cancer-diagnosis
#4
Tomokazu Ishikawa, Tohru Yoneyama, Yuki Tobisawa, Shingo Hatakeyama, Tatsuo Kurosawa, Kenji Nakamura, Shintaro Narita, Koji Mitsuzuka, Wilhelmina Duivenvoorden, Jehonathan H Pinthus, Yasuhiro Hashimoto, Takuya Koie, Tomonori Habuchi, Yoichi Arai, Chikara Ohyama
The low specificity of the prostate-specific antigen (PSA) for early detection of prostate cancer (PCa) is a major issue worldwide. The aim of this study to examine whether the serum PCa-associated α2,3-linked sialyl N-glycan-carrying PSA (S2,3PSA) ratio measured by automated micro-total immunoassay systems (μTAS system) can be applied as a diagnostic marker of PCa. The μTAS system can utilize affinity-based separation involving noncovalent interaction between the immunocomplex of S2,3PSA and Maackia amurensis lectin to simultaneously determine concentrations of free PSA and S2,3PSA...
February 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28241404/hippocampal-neural-activity-reflects-the-economy-of-choices-during-goal-directed-navigation
#5
Valerie L Tryon, Marsha R Penner, Shawn W Heide, Hunter O King, Joshua Larkin, Sheri J Y Mizumori
Distinguishing spatial contexts is likely essential for the well-known role of the hippocampus in episodic memory. We studied whether types of hippocampal neural organization thought to underlie context discrimination is impacted by learned economic considerations of choice behavior. Hippocampal place cells and theta activity were recorded as rats performed a maze-based probability discounting task that involved choosing between a small certain reward or a large probabilistic reward. Different spatial distributions of place fields were observed in response to changes in probability, the outcome of the rats' choice, and whether or not rats were free to make that choice...
February 27, 2017: Hippocampus
https://www.readbyqxmd.com/read/28241401/hippocampal-cortical-contributions-to-strategic-exploration-during-perceptual-discrimination
#6
Joel L Voss, Neal J Cohen
The hippocampus is crucial for long-term memory; its involvement in short-term or immediate expressions of memory is more controversial. Rodent hippocampus has been implicated in an expression of memory that occurs on-line during exploration termed "vicarious trial-and-error" (VTE) behavior. VTE occurs when rodents iteratively explore options during perceptual discrimination or at choice points. It is strategic in that it accelerates learning and improves later memory. VTE has been associated with activity of rodent hippocampal neurons, and lesions of hippocampus disrupt VTE and associated learning and memory advantages...
February 27, 2017: Hippocampus
https://www.readbyqxmd.com/read/28241245/the-burden-of-early-phenotypes-and-the-influence-of-wall-thickness-in-hypertrophic-cardiomyopathy-mutation-carriers-findings-from-the-hcmnet-study
#7
Carolyn Y Ho, Sharlene M Day, Steven D Colan, Mark W Russell, Jeffrey A Towbin, Mark V Sherrid, Charles E Canter, John L Jefferies, Anne M Murphy, Allison L Cirino, Theodore P Abraham, Matthew Taylor, Luisa Mestroni, David A Bluemke, Petr Jarolim, Ling Shi, Lynn A Sleeper, Christine E Seidman, E John Orav
Importance: Sarcomere mutations and left ventricular (LV) hypertrophy (LVH) are cardinal features of hypertrophic cardiomyopathy (HCM). However, little is known about the full spectrum of phenotypic manifestations or how LVH influences disease expression. Objectives: (1) To characterize and assess phenotypic burden in sarcomere mutation carriers (genotype positive [G+]) and (2) to investigate the correlation between LV wall thickness (LVWT) and other disease features in mutation carriers...
February 22, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28241214/assessment-of-the-predictive-validity-of-etiologic-stroke-classification
#8
E Murat Arsava, Johanna Helenius, Ross Avery, Mine H Sorgun, Gyeong-Moon Kim, Octavio M Pontes-Neto, Kwang Yeol Park, Jonathan Rosand, Mark Vangel, Hakan Ay
Importance: The ability of present-day etiologic stroke classification systems to generate subtypes with discrete stroke characteristics is not known. Objective: To test the hypothesis that etiologic stroke subtyping identifies different disease processes that can be recognized through their different clinical courses. Design, Setting, and Participants: We performed a head-to-head evaluation of the ability of the Causative Classification of Stroke (CCS), Trial of Org 10172 in Acute Stroke Treatment (TOAST), and ASCO (A for atherosclerosis, S for small-vessel disease, C for cardiac source, and O for other cause) classification systems to generate etiologic subtypes with different clinical, imaging, and prognostic characteristics in 1816 patients with ischemic stroke...
February 27, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28241132/validation-of-the-german-version-of-the-commitment-to-exercise-scale
#9
Almut Zeeck, Sabine Schlegel, Katrin E Giel, Florian Junne, Christine Kopp, Andreas Joos, Caroline Davis, Armin Hartmann
Pathological forms of exercising are a topic of debate in terms of classification, etiology, and treatment. Validated instruments are a precondition for research in this field. The aim of this study was to validate the German version of the Commitment to Exercise Scale (CES-de). A confirmatory factor analysis was conducted using data from a large community sample (n = 571). In a second study, 100 eating disordered patients, 107 elite athletes and 100 individuals engaged in leisure time sporting activities were compared to assess discriminant validity and psychological correlates...
February 28, 2017: Psychopathology
https://www.readbyqxmd.com/read/28241126/morbidity-after-hemorrhage-in-children-with-untreated-brain-arteriovenous-malformation
#10
Li Ma, Helen Kim, Xiao-Lin Chen, Chun-Xue Wu, Jun Ma, Hua Su, Yuanli Zhao
BACKGROUND: Children with untreated brain arteriovenous malformations (bAVM) are at risk of encountering life-threatening hemorrhage very early in their lives. The primary aim of invasive treatment is to reduce unfavorable outcome associated with a bAVM rupture. A better understanding of the morbidity of bAVM hemorrhage might be helpful for weighing the risks of untreated bAVM and invasive treatment. Our aim was to assess the clinical outcome after bAVM rupture and identify features to predict severe hemorrhage in children...
February 28, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28241044/medico-economic-impact-of-mskcc-non-sentinel-node-prediction-nomogram-for-er-positive-her2-negative-breast-cancers
#11
Hélène Bonsang-Kitzis, Delphine Mouttet-Boizat, Eugénie Guillot, Jean-Guillaume Feron, Virginie Fourchotte, Séverine Alran, Jean-Yves Pierga, Paul Cottu, Florence Lerebours, Denise Stevens, Anne Vincent-Salomon, Brigitte Sigal-Zafrani, François Campana, Roman Rouzier, Fabien Reyal
BACKGROUND: Avoiding axillary lymph node dissection (ALND) for invasive breast cancers with isolated tumor cells or micrometastatic sentinel node biopsy (SNB) could decrease morbidity with minimal clinical significance. PURPOSE: The aim of this study is to simulate the medico-economic impact of the routine use of the MSKCC non-sentinel node (NSN) prediction nomogram for ER+ HER2- breast cancer patients. METHODS: We studied 1036 ER+ HER2- breast cancer patients with a metastatic SNB...
2017: PloS One
https://www.readbyqxmd.com/read/28241029/squamation-and-ecology-of-thelodonts
#12
Humberto G Ferrón, Héctor Botella
Thelodonts are an enigmatic group of Paleozoic jawless vertebrates that have been well studied from taxonomical, biostratigraphic and paleogeographic points of view, although our knowledge of their ecology and mode of life is still scant. Their bodies were covered by micrometric scales whose morphology, histology and the developmental process are extremely similar to those of extant sharks. Based on these similarities and on the well-recognized relationship between squamation and ecology in sharks, here we explore the ecological diversity and lifestyles of thelodonts...
2017: PloS One
https://www.readbyqxmd.com/read/28241028/deploying-a-quantum-annealing-processor-to-detect-tree-cover-in-aerial-imagery-of-california
#13
Edward Boyda, Saikat Basu, Sangram Ganguly, Andrew Michaelis, Supratik Mukhopadhyay, Ramakrishna R Nemani
Quantum annealing is an experimental and potentially breakthrough computational technology for handling hard optimization problems, including problems of computer vision. We present a case study in training a production-scale classifier of tree cover in remote sensing imagery, using early-generation quantum annealing hardware built by D-wave Systems, Inc. Beginning within a known boosting framework, we train decision stumps on texture features and vegetation indices extracted from four-band, one-meter-resolution aerial imagery from the state of California...
2017: PloS One
https://www.readbyqxmd.com/read/28240821/-invited-review-genetic-research-on-alcohol-use-outcomes-in-african-american-populations-a-review-of-the-literature-associated-challenges-and-implications
#14
REVIEW
Danielle M Dick, Peter Barr, Mignonne Guy, Aashir Nasim, Denise Scott
BACKGROUND AND OBJECTIVES: There have been remarkable advances in understanding genetic influences on complex traits; however, individuals of African descent have been underrepresented in genetic research. METHODS: We review the limitations of existing genetic research on alcohol phenotypes in African Americans (AA) including both twin and gene identification studies, possible reasons for underrepresentation of AAs in genetic research, the implications of the lack of racially diverse samples, and special considerations regarding conducting genetic research in AA populations...
February 27, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28240794/phase-contrast-mr-flow-imaging-a-tool-to-determine-hepatic-hemodynamics-in-rats-with-a-healthy-fibrotic-or-cirrhotic-liver
#15
Denise Schaffner, Dominik von Elverfeldt, Peter Deibert, Adhara Lazaro, Irmgard Merfort, Lisa Lutz, Jakob Neubauer, Manfred W Baumstark, Wolfgang Kreisel, Wilfried Reichardt
PURPOSE: To test a magnetic resonance (MR) scanning protocol as a noninvasive tool to determine hepatic hemodynamics and to assess the degree of liver fibrosis in an animal model of liver fibrosis and cirrhosis. MATERIALS AND METHODS: Fifty-four male Wistar rats were studied. Thirty-nine received thioacetamide (TAA) in their drinking water for either 12 or 16 weeks. MR measurements were performed using flow-sensitive 2D phase-contrast MRI and a 9.4T preclinical scanner...
February 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28240742/dna-methylation-mediates-neural-processing-after-odor-learning-in-the-honeybee
#16
Stephanie D Biergans, Charles Claudianos, Judith Reinhard, C Giovanni Galizia
DNA methyltransferases (Dnmts) - epigenetic writers catalyzing the transfer of methyl-groups to cytosine (DNA methylation) - regulate different aspects of memory formation in many animal species. In honeybees, Dnmt activity is required to adjust the specificity of olfactory reward memories and bees' relearning capability. The physiological relevance of Dnmt-mediated DNA methylation in neural networks, however, remains unknown. Here, we investigated how Dnmt activity impacts neuroplasticity in the bees' primary olfactory center, the antennal lobe (AL) an equivalent of the vertebrate olfactory bulb...
February 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28240739/tubular-peroxiredoxin-3-as-a-predictor-of-renal-recovery-from-acute-tubular-necrosis-in-patients-with-chronic-kidney-disease
#17
Chia-Lin Wu, Tzu-Cheng Su, Chia-Chu Chang, Chew-Teng Kor, Chung-Ho Chang, Tao-Hsiang Yang, Ping-Fang Chiu, Der-Cherng Tarng
Peroxiredoxin 3 (PRX3) is a mitochondrial antioxidant that regulates apoptosis in various cancers. However, whether tubular PRX3 predicts recovery of renal function following acute kidney injury (AKI) remains unknown. This retrospective cohort study included 54 hospitalized patients who had AKI with biopsy-proven acute tubular necrosis (ATN). The study endpoint was renal function recovery within 6 months. Of the 54 enrolled patients, 25 (46.3%) had pre-existing chronic kidney disease (CKD) and 33 (61%) recovered renal function...
February 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28240584/type-i-and-iii-collagen-turnover-is-increased-in-axial-spondyloarthritis-and-psoriatic-arthritis-associations-with-disease-activity-and-diagnostic-capacity
#18
Natasja Stæhr Gudmann, Anne Sofie Siebuhr, Anne Friesgaard Christensen, Leif Ejstrup, Grith Lykke Sørensen, Anne Gitte Loft, Morten Asser Karsdal, Anne-Christine Bay-Jensen, Heidi Lausten Munk, Peter Junker
OBJECTIVES: To investigate the turnover of type I and III collagen by neo-epitope markers in patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). METHODS: Patients with PsA (n=101) or axSpA (n=110) and healthy subjects (n=120) were included. Demographic and clinical data were recorded. Markers of type I and III collagen were quantified by RIA (ICTP) or ELISA (C1M and C3M). Non-parametric statistics were applied for intergroup comparisons and correlation studies...
February 24, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28240331/a-multi-responsive-luminescent-sensor-for-organic-small-molecule-pollutants-and-metal-ions-based-on-a-4d-4f-metal-organic-framework
#19
Huili Ma, Lu Wang, Jinghuo Chen, Xuejing Zhang, Liang Wang, Na Xu, Guangming Yang, Peng Cheng
Two silver(i)-lanthanide(iii) heterometallic-organic frameworks (HMOFs) {[Ln3Ag3(BPDC)5(OX)(H2O)7]·7H2O}n (Ln = Tb (1), Gd (2)) have been synthesized via a mixed ligand approach using 2,2'-bipyridine-3,3'-dicarboxylic acid (H2BPDC) and oxalic acid (H2OX) under hydrothermal conditions. Single crystal X-ray diffraction studies showed a (3,4,5)-connected new topology of {3·4(2)·5·6(2)}{3·4(3)·5(2)·6(3)·7}{3·5·6(2)·9·10}{4(2)·5·6(3)}{4(2)·5}{4(2)·6}{4(3)·5·6(2)}{4(3)·6(3)}{4(3)·6(4)·8(2)·10}...
February 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28240292/the-role-of-dorsal-hippocampal-dopamine-d1-type-receptors-in-social-learning-social-interactions-and-food-intake-in-male-and-female-mice
#20
Richard Matta, Angela Nicole Tiessen, Elena Choleris
The neurobiological mechanisms underlying social learning (ie, in which an animals learning is influenced by another) are slowly being unraveled. Previous work with systemic treatments shows that dopamine (DA) D1-type receptors mediate social learning in the social transmission of food preferences (STFP) in mice (Choleris et al, 2011). This study examines the involvement of one brain region underlying this effect. The ventral tegmental area has dopaminergic projections to many limbic structures, including the hippocampus-a site important for social learning in the STFP in rodents...
February 27, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
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