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https://www.readbyqxmd.com/read/28538437/single-operator-ultrasound-guided-central-venous-catheter-insertion-verifies-proper-tip-placement
#1
Ori Galante, Tzachi Slutsky, Lior Fuchs, Alexander Smoliakov, Yuval Mizrakli, Victor Novack, Evgeni Brotfein, Moti Klein, Amit Frenkel, Leonid Koifman, Yaniv Almog
OBJECTIVES: To evaluate whether a single-operator ultrasound-guided, right-sided, central venous catheter insertion verifies proper placement and shortens time to catheter utilization. DESIGN: Prospective observational study with historical controls. SETTING: Adult ICUs. PATIENTS: Sixty-four consecutive patients undergoing ultrasound-assisted right-sided central venous catheterization compared with 92 serial historic controls who had unassisted central catheter insertion at the same sites...
May 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28534558/-proposing-a-physiological-model-for-emergency-department-operating-principles-classification-of-overcrowding-and-guidelines-for-redesign
#2
M Herrera Carranza, F Aguado Correa, N Padilla Garrido, F López Camacho
The operation of Emergency Departments (ED) is determined by demand, their own organizational structures and the connection to other medical care levels. When these elements are not simultaneous, it hinders patient flow and decreases capacity, making it necessary to employ a systemic approach to the chain of emergency care as a single operational entity. With this theoretical orientation, we suggest a conceptual model similar to the physiological cardiac output, in which the preload is the demand, the contractile or flow pump is the organizational structure, the afterload is the hospital, the pre-ED valve is primary care and outpatient emergencies, and the post-ED valve is the diagnostic support services and the specialist consultants...
April 30, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/28522970/automatic-optimization-of-the-computation-graph-in-the-nengo-neural-network-simulator
#3
Jan Gosmann, Chris Eliasmith
One critical factor limiting the size of neural cognitive models is the time required to simulate such models. To reduce simulation time, specialized hardware is often used. However, such hardware can be costly, not readily available, or require specialized software implementations that are difficult to maintain. Here, we present an algorithm that optimizes the computational graph of the Nengo neural network simulator, allowing simulations to run more quickly on commodity hardware. This is achieved by merging identical operations into single operations and restructuring the accessed data in larger blocks of sequential memory...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28516094/combined-transapical-transcatheter-aortic-valve-replacement-and-thoracic-endovascular-aortic-repair-for-severe-aortic-stenosis-and-arch-aneurysm
#4
Yuanjia Zhu, Eric E Roselli, Jay J Idrees, Samir Kapadia, Lars G Svensson
An 83-year-old male with multiple comorbidities presented with critical aortic stenosis and a saccular aortic arch aneurysm. Through a mini thoracotomy, a balloon expandable transcatheter aortic valve was delivered transapically. A thoracic stent graft was then delivered through the prosthetic valve and deployed in the arch, while a covered stent was deployed in the left common carotid artery. Three-year postoperative computed tomography showed a thrombosed arch aneurysm with decreased size. This case demonstrates the feasibility of using combined transapical transcatheter technologies to treat multicomponent disease in a high-risk patient during a single operation...
October 2016: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/28511237/performance-of-a-fully-disposable-digital-single-operator-cholangiopancreatoscope
#5
Raj J Shah, Isaac Raijman, Brian Brauer, Bora Gumustop, Douglas K Pleskow
Background and study aim Our aim was to evaluate the first use in humans of a new, single-use, digital, single-operator intraductal cholangiopancreatoscopy system (IDCP). Patients and methods Data were collected retrospectively from four US institutions between February 2015 and April 2015. The visual impression of neoplasia or benign findings with IDCP was determined by the performing endoscopist. High grade dysplasia, intraductal papillary mucinous neoplasm, neuroendocrine tumor, and malignancy were categorized as neoplasia...
May 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/28511235/direct-peroral-cholangioscopy-with-a-new-anchoring-technique-using-the-guide-probe-of-kautz-first-clinical-experiences
#6
Frank Lenze, Tobias M Nowacki, Torsten Beyna, Hansjoerg Ullerich
Background and study aims We present the first clinical results of a new tandem technique for direct peroral cholangioscopy using a standard ultraslim upper gastrointestinal endoscope and a guide probe that was originally developed for the non-transendoscopic placement of biliary endoprostheses (guide probe of Kautz; MTW, Wesel, Germany). Patients and methods Twenty direct peroral cholangioscopy procedures were performed with the new anchor-assisted method using the guide probe of Kautz in a single center and were retrospectively analyzed...
May 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/28510742/drug-safety-in-paediatric-anaesthesia
#7
J Kaufmann, A R Wolf, K Becke, M Laschat, F Wappler, T Engelhardt
Life-threatening drug errors are more common in children than in adults. This is likely to be because of their variations in age and weight, combined with the occasional exposure of most anaesthetists to paediatric patients. Drug administration in anaesthesia is mostly undertaken by a single operator and thus represents a potentially greater risk compared with other areas of medicine. This increased risk is believed to be offset by anaesthetists working with only a limited number of drugs on a very frequent and repetitive basis...
May 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28485455/cationic-polycyclization-of-ynamides-building-up-molecular-complexity
#8
Cédric Theunissen, Benoît Métayer, Morgan Lecomte, Nicolas Henry, Hwai-Chien Chan, Guillaume Compain, Phidéline Gérard, Christian Bachmann, Naima Mokhtari, Jérome Marrot, Agnès Martin-Mingot, Sébastien Thibaudeau, Gwilherm Evano
Polycyclization reactions are among the most efficient synthetic tools for the synthesis of complex, polycyclic molecules in a single operation from simple starting materials. We report in this manuscript a full account on the discovery and development of a novel cationic polycyclization from readily available ynamides. Simple activation of these building blocks under acidic conditions enables the generation of highly reactive activated keteniminium ions, which triggers an unprecedented cationic polycyclization yielding highly substituted polycyclic nitrogen heterocycles possessing up to seven fused cycles and three contiguous stereocenters...
May 23, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28467473/users-of-the-main-smartphone-operating-systems-ios-android-differ-only-little-in-personality
#9
Friedrich M Götz, Stefan Stieger, Ulf-Dietrich Reips
The increasingly widespread use of mobile phone applications (apps) as research tools and cost-effective means of vast data collection raises new methodological challenges. In recent years, it has become a common practice for scientists to design apps that run only on a single operating system, thereby excluding large numbers of users who use a different operating system. However, empirical evidence investigating any selection biases that might result thereof is scarce. Henceforth, we conducted two studies drawing from a large multi-national (Study 1; N = 1,081) and a German-speaking sample (Study 2; N = 2,438)...
2017: PloS One
https://www.readbyqxmd.com/read/28464459/accuracy-of-point-of-care-ultrasonography-for-diagnosing-acute-appendicitis-a-systematic-review-and-meta-analysis
#10
Matthew J Fields, Joshua Davis, Carl Alsup, Amanda Bates, Arthur Au, Srikar Adhikari, Isaac Farrell
INTRODUCTION: The use of ultrasonography to diagnose appendicitis has become increasingly common over recent years and is well-established. More recently, point of care ultrasonography (POCUS) has also been studied for the diagnosis of appendicitis, which may also prove a valuable diagnostic tool. The purpose of this study is through systematic review and meta-analysis to identify the test characteristics of POCUS, specifically ultrasonography performed by a non-radiologist physician, in accurately diagnosing acute appendicitis in patients of any age...
May 2, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28451237/a-palladium-catalyzed-synthesis-of-hetero-aryl-substituted-imidazoles-from-aryl-halides-imines-and-carbon-monoxide
#11
Jevgenijs Tjutrins, Bruce A Arndtsen
We describe here a tandem catalytic route to prepare imidazoles in a single operation from aryl iodides, imines and CO. The reaction involves a catalytic carbonylation of aryl halides with imines to form 1,3-dipoles, which undergo spontaneous 1,3-dipolar cycloaddition. Overall, this offers an alternative to coupling reactions to construct the (hetero)aryl-imidazole motif, where variation of the building blocks can allow the synthesis of broad families of imidazoles with independent control of all substituents...
February 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28445200/the-nasal-tip-rotation-flap-for-reconstruction-of-the-lateral-nasal-tip-anterior-ala-and-soft-triangle-the-authors-experience-with-55-patients
#12
Anastasia Benoit, S Tyler Hollmig, Brian C Leach
BACKGROUND: Defects of the lateral nasal tip, anterior ala, and soft triangle subunits lack reconstructive options that are consistently satisfactory. For such defects, the novel anterior-based nasal tip rotation flap provides functional and aesthetic results in a single operative session. OBJECTIVE: To describe the authors' experience with the nasal tip rotation flap, including patient selection and design modifications to enhance aesthetic success. METHODS: An IRB-approved retrospective database review of nasal tip rotation flap repairs was performed at the Medical University of South Carolina and Stanford University Medical Center...
April 24, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28420217/microfluidic-ebg-sensor-based-on-phase-shift-method-realized-using-3d-printing-technology
#13
Vasa Radonić, Slobodan Birgermajer, Goran Kitić
In this article, we propose a novel microfluidic microstrip electromagnetic band gap (EBG) sensor realized using cost-effective 3D printing technology. Microstrip sensor allows monitoring of the fluid properties flowing in the microchannel embedded between the microstrip line and ground plane. The sensor's operating principle is based on the phase-shift method, which allows the characterization at a single operating frequency of 6 GHz. The defected electromagnetic band gap (EBG) structure is realized as a pattern in the microstrip ground plane to improve sensor sensitivity...
April 18, 2017: Sensors
https://www.readbyqxmd.com/read/28417538/synthesis-of-long-oxahelicenes-by-polycyclization-in-a-flow-reactor
#14
Jindřich Nejedlý, Michal Šámal, Jiří Rybáček, Miroslava Tobrmanová, Florence Szydlo, Christophe Coudret, Maria Neumeier, Jaroslav Vacek, Jana Vacek Chocholoušová, Miloš Buděšínský, David Šaman, Lucie Bednárová, Ladislav Sieger, Irena G Stará, Ivo Starý
A series of oxahelicenes composed of ortho/meta-annulated benzene/pyridine and 2H-pyran rings were synthesized on the basis of the cobalt(I)-mediated (or rhodium(I)- or nickel(0)-mediated) double, triple, or quadruple [2+2+2] cycloisomerization of branched aromatic hexa-, nona-, or dodecaynes, thus allowing the construction of 6, 9, or 12 rings in a single operation. The use of a flow reactor was found to be beneficial for the multicyclization reactions. The stereogenic centers present in some of the oligoynes steered the helical folding in such a way that the final oxa[9]-, [13]-, [17]- and [19]helicenes were obtained in both enantiomerically and diastereomerically pure form...
April 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28403110/a-feasibility-study-of-digital-single-operator-cholangioscopy-for-diagnostic-and-therapeutic-procedure-with-videos
#15
Miyuki Imanishi, Takeshi Ogura, Yoshitaka Kurisu, Saori Onda, Wataru Takagi, Atsushi Okuda, Akira Miyano, Mio Amano, Nobu Nishioka, Daisuke Masuda, Kazuhide Higuchi
Recently, the novel SpyGlass DS Direct Visualization system (SPY DS) has become available. This system offers several advantages over the conventional SPYGlass system. This study evaluated the clinical feasibility and efficacy of diagnostic and therapeutic procedures for biliary disorder using SPY DS.In this retrospective study, consecutive patients who had biliary disorder were enrolled between November 2015 and February 2016. All patients could not be diagnosed or treated by standard endoscopic retrograde cholangiopancreatography in our hospital or at another hospital...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28396191/prostate-artery-embolization-via-transradial-or-transulnar-versus-transfemoral-arterial-access-technical%C3%A2-results
#16
Shivank Bhatia, Sardis H Harward, Vishal K Sinha, Govindarajan Narayanan
PURPOSE: To compare safety and feasibility of prostate artery embolization (PAE) via transradial/transulnar access (TR/UA) and transfemoral access (TFA). MATERIALS AND METHODS: A retrospective analysis was conducted for 3 cohorts: the first 32 consecutive PAE procedures performed via TFA (initial TFA, January 2014 to August 2015), the following 32 procedures performed via TFA (advanced TFA, August 2015 to February 2016), and the first 32 procedures performed via TR/UA (February 2016 to July 2016)...
April 7, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28394387/photoredox-catalyzed-oxytrifluoromethylation-of-allenes-stereoselective-synthesis-of-2-trifluoromethylated-allyl-acetates
#17
Ren Tomita, Takashi Koike, Munetaka Akita
We have developed novel oxytrifluoromethylation of aryl-substituted allenes by photoredox catalysis. The present photocatalytic system allows direct and stereoselective synthesis of 2-CF3-allyl acetates bearing tetrasubstituted CF3-alkene scaffolds in a single operation. The obtained CF3-allyl acetates can be applied to further functionalization as CF3-containing building blocks.
April 10, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28389694/utility-of-the-ginza-forceps-for-superficial-phlebectomy-during-endovenous-laser-ablation-of-the-great-saphenous-vein
#18
Takeshi Baba, Takao Ohki, Yuji Kanaoka, Koji Maeda, Kenjirou Kaneko, Masayuki Hara, Kota Shukuzawa, Soichiro Fukushima
PURPOSE: To evaluate the efficiency of using the Ginza forceps (DVx, Tokyo, Japan), which have a long shaft and strong grip, for superficial phlebectomy with the stab avulsion technique, during simultaneous endovenous laser ablation (EVLA) of the great saphenous vein (GSV). METHODS: The subjects were patients treated with EVLA performed by a single operator at one institution. All patients had a GSV diameter of 4-10 mm and an EVLA length of the GSV of >20 cm...
April 7, 2017: Surgery Today
https://www.readbyqxmd.com/read/28381356/blocking-screws-for-alignment-control-in-intramedullary-limb-lengthening
#19
Julian Fürmetz, Stefan Bösl, James Schilling, Florian Wolf, Nikolaus Degen, Peter H Thaller
Simultaneous deformity correction in the frontal and sagittal plane becomes more and more an important part of intramedullary lengthening to avoid further operative procedures. Such as in fracture treatment blocking screws can be used for alignment control if osteotomy is performed in the metaphyseal bone. 31 intramedullary lengthening procedures between 2009 and 2011 were retrospectively analysed for precision of simultaneous deformity correction. The average planned correction to the HKA was 2.4° (0.1°-8...
March 31, 2017: Injury
https://www.readbyqxmd.com/read/28380618/temporal-spatial-inter-and-intra-cow-repeatability-of-thermal-imaging
#20
D T Byrne, D P Berry, H Esmonde, N McHugh
The objective of the present study was to quantify the within- and between-cow, operator, and day variances of various descriptive temperature parameters from different anatomical areas captured using thermal images on Holstein-Friesian cows. Three experiments were undertaken. In Exp. 1, 30 images were captured by a single operator of each of the eye, hoof, and udder from each of 45 cows; in Exp. 2, three different operators captured eye and hoof images from 12 cows; and in Exp. 3, eye and hoof images were captured by a single operator from 8 cows over a 5-d period...
February 2017: Journal of Animal Science
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