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https://www.readbyqxmd.com/read/28935012/-combining-3d-ctba-and-3d-vats-single-operation-hole-to-%C3%A2-anatomical-segmentectomy-in-the-treatment-of-non-small-cell-lung-cancer
#1
Xiaowei She, Yunbin Gu, Chun Xu, Xinyu Song, Chang Li, Cheng Ding, Jun Chen, Yongsheng Gong, Jun Zhao
BACKGROUND: China is a high-incidence area of lung cancer, and its morbidity and mortality were the highest in malignant tumors. At present, the popularization of low-dose computed tomography (CT) examination has significantly improved the detection rate of early lung cancer, anatomical segmentectomy is currently widely used early in non-small cell lung cancer (NSCLC) and those who cannot tolerate lobectomy in patients with lung cancer. However, the anatomical structure of segment and its surgical operation is relatively complex, lead to segmentectomy has a high risk and difficulty...
September 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28922533/catalytic-enantioselective-carbopalladation-c-h-functionalization-with-statistical-amplification-of-product-enantiopurity-a-convertible-linker-approach
#2
Shuo Tong, Aurore Limouni, Qian Wang, Mei-Xiang Wang, Jieping Zhu
We demonstrated that combining a catalytic enantioselective reaction with dimerization in a single operation is an efficient way to upgrade the enantiomeric excesses (ee) of the product. Palladium-catalyzed reaction of N-(2-iodophenyl)-N-methyl methacrylamide derivatives with oxadiazole afforded, via a double enantioselective carbopalladation/intermolecular direct heteroarene C-H alkylation cascade, homodimers in good yields with excellent ee. The dimer was subsequently elaborated to the monomer in which the linker (oxadiazole) was incorporated into the target product...
September 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28920679/regioselective-synthesis-of-2-4-5-trisubstituted-oxazoles-and-ketene-aminals-via-hydroamidation-and-iodo-imidation-of-ynamides
#3
Rajendra Kumar Mallick, Baskaran Prabagar, Akhila Kumar Sahoo
A novel and straightforward protocol is demonstrated for the synthesis of highly substituted oxazole from readily accessible ynamides in the presence of ytterbium(III) trifluoromethanesulfonate [Yb(OTf)3], N-iodosuccinimide (NIS), and acetonitrile. Multiple oxazole skeletons in the aryl-periphery are constructed in a single operation for the first time. The hydroamidation and iodo-imidation of ynamides to tri- and tetra-substituted ketene aminals is exemplified. An isotope labeling experiment is used to identify the oxygen source in this transformation...
September 18, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28902514/chemoselective-double-annulation-of-two-different-isocyanides-rapid-access-to-trifluoromethylated-indole-fused-heterocycles
#4
Yuelei Gao, Zhongyan Hu, Jinhuan Dong, Jun Liu, Xianxiu Xu
An unprecedented chemoselective double annulation of α-trifluoromethylated isocyanides with o-acylaryl isocyanides has been developed. This new reaction provides a rapid, efficient, and complete atom-economic strategy for the synthesis of trifluoromethylated oxadiazino[3,2-a]indoles in a single operation from readily available starting materials. Isocyanide insertion into C═O double bonds is disclosed for the first time as indicated by the results of (18)O-labeling experiment. A mechanism for this domino reaction is proposed involving chemoselective heterodimerization of two different isocyanides, followed by indole-2,3-epoxide formation and rearrangement...
September 13, 2017: Organic Letters
https://www.readbyqxmd.com/read/28890785/staged-approach-for-surgical-management-of-a-true-femoral-artery-aneurysm-combined-with-bilateral-iliac-artery-aneurysms
#5
Ahmet Dolapoglu, Serkan Ertugay, Hakan Posacioglu
True femoral artery aneurysm is a rare vascular entity and is often associated with aortic or peripheral aneurysms. Life-threatening complications associated with peripheral arterial aneurysms include rupture, thrombosis, and embolization. In patients with multiple aneurysms, any symptomatic aneurysms should be treated first; in asymptomatic patients, the aneurysms can be repaired either simultaneously in a single operation or serially in a staged procedure. We report a case of concomitant true femoral aneurysm and bilateral iliac artery aneurysms, which were treated with a combination of open surgical and endovascular techniques...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28859892/fistulous-complications-following-radical-cystectomy-for-bladder-cancer-analysis-of-a-large-modern-cohort
#6
Zachary L Smith, Scott C Johnson, Shay Golan, J Riley McGinnis, Gary D Steinberg, Norm D Smith
PURPOSE: Fistula formation is a rare and poorly described complication following radical cystectomy with urinary diversion. We sought to identify patients who experienced any type of fistulous complication and analyze the risk factors for formation as well as management outcomes. MATERIALS AND METHODS: We performed a retrospective review of patients who underwent radical cystectomy for bladder cancer at our institution. Patients who experienced any fistula were identified...
August 28, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28859228/performance-characteristics-of-vibration-controlled-transient-elastography-for-evaluation-of-non-alcoholic-fatty-liver-disease
#7
Raj Vuppalanchi, Mohammad S Siddiqui, Mark L Van Natta, Erin Hallinan, Danielle Brandman, Kris Kowdley, Brent A Neuschwander-Tetri, Rohit Loomba, Srinivas Dasarathy, Manal Abdelmalek, Edward Doo, James A Tonascia, David E Kleiner, Arun J Sanyal, Naga Chalasani
BACKGROUND: Vibration-controlled transient elastography (VCTE) estimates liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) which are noninvasive assessments of hepatic fibrosis and steatosis respectively. However, prior VCTE studies reported high failure rate in patients with non-alcoholic fatty liver disease (NAFLD). AIM: To examine the performance characteristics of Fibroscan 502 Touch with two probes, medium (M+) and extra-large (XL+), in patients with NAFLD in a multicenter setting...
August 31, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28843586/a-single-operator-learning-curve-analysis-for-the-endoscopic-sleeve-gastroplasty
#8
Monica Saumoy, Yecheskel Schneider, Xi Kathy Zhou, Alpana Shukla, Michel Kahaleh, Louis Aronne, Reem Z Sharaiha
BACKGROUND AND AIMS: Endoscopic sleeve gastroplasty (ESG) is a novel, incisionless technique for gastric volume reduction to promote weight loss. Our aim was to describe the learning curve for performing ESG using a prospective case series. METHODS: Using a prospective case series design, we analyzed the first 128 consecutive patients at a tertiary-care academic medical center who underwent ESG performed by a single operator from August 2013 to December 2016. Efficiency (refining performance to decrease procedure time) and mastery (absence of outliers) for performing the ESG was evaluated by using a penalized basis-spline regression and cumulative sum (CUSUM) analysis...
August 23, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28829139/sequential-1-4-and-2-3-annulation-of-prop-2-ynylsulfonium-salts-access-to-hexahydropyrrolo-3-2-b-indoles
#9
Penghao Jia, Qinglong Zhang, Qima Ou, You Huang
A powerful sequential [1 + 4]- and [2 + 3]-annulation has been developed using prop-2-ynylsulfonium salts and sulfonyl-protected o-amino aromatic aldimines, affording a series of hexahydropyrrolo[3,2-b]indoles in high yields. Prop-2-ynylsulfonium salts act as C2 synthons in the reaction, and fused rings containing two five-membered azaheterocycles can be constructed in a single operation with readily accessible starting materials.
August 22, 2017: Organic Letters
https://www.readbyqxmd.com/read/28816312/palladium-catalyzed-tandem-cyclization-sulfonylation-of-homoallenyl-amides-with-sodium-sulfinates
#10
Yimei Wan, Jian Zhang, Yongtao Chen, Lichun Kong, Fang Luo, Gangguo Zhu
A palladium-catalyzed cyclizative sulfonylation of homoallenyl amides using sodium sulfinates as the sulfonylation reagent and PhI(O2CCF3)2 as the oxidant has been realized. The reaction proceeds at room temperature and produces structurally diverse 2-amino-5-sulfonylmethylfurans in good to excellent yields. A Pd(ii)/Pd(iv) catalytic cycle has been proposed for the formation of sulfonylated furans. The concurrent formation of a furan moiety and a C(sp(3))-sulfur bond in a single operation makes it a very attractive method for organic synthesis...
August 30, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28815760/impact-microindentation-consistency-of-serial-measurements-and-alterations-in-patients-with-paget-s-disease-of-the-tibia
#11
Frank Malgo, Neveen A T Hamdy, Socrates E Papapoulos, Natasha M Appelman-Dijkstra
Impact microindentation is a new technique for the in vivo measurement of tissue-level properties of cortical bone in humans. To address issues related to the proper application of IMI in clinical practice and to directly examine cortical bone properties in patients with tibia pathology, we studied 11 subjects without tibia pathology and 9 patients with Paget's disease of the tibia in biochemical remission after bisphosphonate treatment. Serial indentations in the tibiae of both legs were performed in all subjects by a single operator until 10 adequate measurements were obtained in each tibia...
August 16, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28807798/clinically-undetected-retinal-breaks-causing-retinal-detachment-options-for-management
#12
REVIEW
Deepak Gupta, Jared Ching, Paul E Tornambe
The successful detection of retinal breaks is a critical step in rhegmatogenous retinal detachment (RRD) surgery in order to prevent persistent/recurrent RRDs. Not all retinal breaks causing retinal detachments are obvious. Retinal breaks may be obscured due to opacities that are either anterior-segment related, lens related or posterior-segment related. Rules to identify breaks based on sub-retinal fluid (SRF) configuration are more difficult to apply in pseudophakic, aphakic, encircled eyes, and eyes with repeat detachments and those with proliferative vitreoretinopathy (PVR)...
August 11, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28802361/functional-endoscopic-sinus-surgery-improves-the-quality-of-life-in-children-suffering-from-chronic-rhinosinusitis-with-nasal-polyps
#13
Melina Fetta, Nikolaos S Tsilis, John V Segas, Thomas P Nikolopoulos, Petros V Vlastarakos
OBJECTIVE: To evaluate the impact of FESS in children with chronic rhinosinusitis with nasal polyps, regarding their overall postoperative quality-of-life (QoL) and constituent QoL domains. Potential differences between cystic fibrosis (CF) sufferers and non-sufferers, or cases with recurrent sinonasal polyposis versus single-operations were also explored. METHODS: 39 children were studied. The mean patient age was 10.9 years; four children suffered from cystic fibrosis...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28800388/rapid-access-to-nanographenes-and-fused-heteroaromatics-by-palladium-catalyzed-annulative-%C3%AF-extension-reaction-of-unfunctionalized-aromatics-with-diiodobiaryls
#14
Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Efficient and rapid access to nanographenes and π-extended fused heteroaromatics is important in materials science. Herein, we report a palladium-catalyzed efficient one-step annulative π-extension (APEX) reaction of polycyclic aromatic hydrocarbons (PAHs) and heteroaromatics, producing various π-extended aromatics. In the presence of a cationic Pd complex, triflic acid, silver pivalate, and diiodobiaryls, diverse unfunctionalized PAHs and heteroaromatics were directly transformed into larger PAHs, nanographenes, and π-extended fused heteroaromatics in a single step...
August 11, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28782466/current-status-of-renal-artery-angioplasty-and-stenting-for-resistant-hypertension-a-case-series-and-review-of-the-literature
#15
Antonis S Manolis, Antonis A Manolis, Helen Melita
BACKGROUND: Renal artery stenosis (RAS) has a high prevalence in older patients, especially in the context of general atherosclerosis. It is frequently associated with resistant hypertension and impaired renal function and their attendant consequences. The issue whether revascularization via percutaneous renal angioplasty and stenting (PRA/S) can benefit these patients remains unsettled. OBJECTIVE: To present a case series of patients with refractory hypertension and RAS undergoing PRA/S and also to provide an extensive review of the literature on the current status of PRA/S for resistant hypertension...
August 4, 2017: Current Hypertension Reviews
https://www.readbyqxmd.com/read/28777096/beam-projections-and-radiation-exposure-in-transradial-and-transfemoral-approaches-during-coronary-angiography
#16
Ali Tarighatnia, Amirhossien Mohammadalian, Morteza Ghojazade, Leili Pourafkari, Alireza Farajollahi
OBJECTIVE: We aimed to compare the operator and patient radiation exposure in standard projections during elective diagnostic coronary angiography procedures via transradial (TRA) versus transfemoral (TFA) approaches. METHODS: In this analytical cross-sectional study, a total of 202 consecutive patients who were candidates for diagnostic coronary angiography were randomized to undergo the procedure via TFA or TRA approaches (101 in each group). Patients with abnormal Allen test and history of coronary artery bypass surgery, valvular heart disease, and unsuccessful coronary angiography were excluded from the study...
August 2, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28766569/ectopic-hepatocellular-carcinoma-within-a-choledochal-cyst-diagnosed-using-single-operator-digital-cholangioscopy
#17
Nayana E George, Saikiran Raghavapuram, Debdeep Banerjee, Mohammad Al-Shoha, Faysal Fedda, Benjamin Tharian
No abstract text is available yet for this article.
August 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28757333/heterogeneity-of-different-tools-for-detecting-the-prevalence-of-frailty-in-nursing-homes-feasibility-and-meaning-of-different-approaches
#18
N Martínez-Velilla, Pablo Aldaz Herce, Álvaro Casas Herrero, Marta Gutiérrez-Valencia, Mikel López Sáez de Asteasu, Alberto Sola Mateos, Ana Conde Zubillaga, Berta Ibáñez Beroiz, Arkaitz Galbete Jiménez, Mikel Izquierdo
BACKGROUND AND OBJECTIVE: The identification of frail individuals has been recognized as a priority for the effective implementation of healthy aging strategies. Only a limited number of studies have examined frailty in nursing homes, and there is a big heterogeneity in the methods used. The primary objective of this study was to determine the prevalence and feasibility of different frailty screening tools in nursing homes as well as its relationship with multimorbidity and disability...
July 27, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28728944/ultrasound-guided-thoracic-paravertebral-block-cadaveric-study-in-foxes-vulpes-vulpes
#19
Paolo Monticelli, Ian Jones, Jaime Viscasillas
OBJECTIVE: To describe an ultrasound-guided thoracic paravertebral block in canidae. STUDY DESIGN: Prospective, experimental, cadaveric study. ANIMALS: Twelve thawed fox cadavers. METHODS: A 15 MHz linear transducer was used to visualize the paravertebral space at the level of the fifth thoracic vertebrae. Iohexol (300 mg mL(-1)) at 0.2 mL kg(-1) was injected into the right and left paravertebral spaces under ultrasound guidance using a Tuohy needle...
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28721463/exstrophy-bladder-reconstruction-or-diversion-for-the-underprivileged
#20
REVIEW
Yogesh Kumar Sarin, Virender Sekhon
The surgical techniques for management of bladder exstrophy epispadias complex have evolved from staged reconstruction, complete primary repair to radical mobilization. Post-operative complications add to the multiplicity of surgical procedures at each step. The end results are variable with many achieving continence rates of 85-89% only after bladder augmentation and clean intermittent catheterization. The situation is further complicated in resource-poor settings, where illiteracy and poverty are the driving factors for choosing a single operative procedure for creation of low pressure reservoir aiming at upper tract preservation and good primary continence...
July 18, 2017: Indian Journal of Pediatrics
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