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https://www.readbyqxmd.com/read/29164419/rhegmatogenous-retinal-detachment-in-uveitis
#1
Joeri De Hoog, Josianne C Ten Berge, Fahriye Groen, Aniki Rothova
BACKGROUND: Retinal detachment is more common among uveitis patients than in the general population. Here, we aimed to assess the prevalence of rhegmatogenous retinal detachment (RRD) in a uveitis population. METHODS: We retrospectively studied 851 uveitis patients, recording characteristics such as uveitis duration, anatomical location, and cause; RRD occurrence; proliferative vitreoretinopathy (PVR) at presentation; surgical approach; reattachment rate; and initial and final visual acuity (VA)...
November 21, 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29155912/a-novel-sulfonamide-non-classical-carbenoid-a-mechanistic-study-for-the-synthesis-of-enediynes
#2
Theodore O P Hayes, Ben Slater, Richard A J Horan, Marc Radigois, Jonathan D Wilden
Alkynyl sulfonamides undergo sequential 1,4- then 1,2-addition/rearrangement with lithium acetylides to yield enediynes in the absence of any promoters or catalysts. Mechanistic investigations suggest that the reaction proceeds via 1,4-conjugate addition of the nucleophile to the unsaturated system to give a key alkenyl lithium species which is stabilised by an intramolecular coordination effect by a sulfonamide oxygen atom. This species can be considered a vinylidene carbenoid given the carbon atom bears both an anion (as a vinyllithium) and a leaving group (the sulfonamide)...
November 20, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29142543/career-choices-of-medical-doctors-at-graduate-level-a-multicenter-study
#3
Sadaf Zia, Maisam Abbas, Mehreen Sulaiman, Salman Matiullah Sheikh
Objective: To find out the specialty choices being taken by Final year Medical students and graduate Doctors. Method: This is a cross sectional survey study which was conducted over two months from 1(st) November to 31(st) December 2016. Final year students and house job doctors were asked for the filling of Performa, after filling the consent form. A self-developed, anonymous questionnaire was used to conduct the study using close ended type of questions. This was a multi-center study conducted at Dow International Medical College and Jinnah Medical and Dental College...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29137898/antiseptics-commonly-used-in-total-joint-arthroplasty-interact-and-may-form-toxic-products
#4
Sean T Campbell, Lawrence H Goodnough, Chase G Bennett, Nicholas J Giori
BACKGROUND: Multiple antiseptics have been described for use in total joint arthroplasty infection, and the use of multiple antiseptic solutions during a single operation has been described. Our clinical experience is that chlorhexidine (CHX) and Dakin's solution (NaOCl) interact and form a precipitate. The purpose of this study is to determine whether this reaction could be replicated in a laboratory setting, and to determine if other commonly used antiseptics also visibly react when mixed...
November 11, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29137498/core-needle-biopsy-of-thyroid-nodules-outcomes-and-safety-from-a-large-single-center-single-operator-study
#5
Jooae Choe, Jung Hwan Baek, Hye Sun Park, Young Jun Choi, Jeong Hyun Lee
Background There currently remains a debate over the use of core needle biopsy (CNB) or fine needle aspiration (FNA) for diagnosis of thyroid nodules. The major drawbacks of previous CNB studies include heterogeneity of the study population, variable techniques, devices, and operator experience affecting the outcome of the procedure. Purpose To assess the diagnostic performance and safety of CNB of thyroid nodules performed by a single experienced operator in consecutive patients. Material and Methods From January 2012 to December 2012, 538 thyroid nodules that underwent CNB were retrospectively evaluated...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29135800/outcomes-of-pneumatic-retinopexy-performed-by-vitreoretinal-fellows
#6
Parisa Emami-Naeini, Vivian S Vuong, Steven Tran, Lawrence S Morse, Ala Moshiri, Susanna S Park, Glenn Yiu
PURPOSE: To evaluate the anatomical and visual outcomes of patients who underwent pneumatic retinopexy by vitreoretinal fellows. METHODS: We included 198 eyes (198 patients) that underwent pneumatic retinopexy by vitreoretinal fellows at a single academic institution between November 2002 and June 2016. Main outcomes were single-operation success and final anatomical success in retinal reattachment, as well as visual acuity at 3 months and 6 months after treatment...
November 10, 2017: Retina
https://www.readbyqxmd.com/read/29126239/morphometric-analysis-of-the-umbilicus-according-to-age
#7
Nicolas Correia, Laura Jayyosi, Sergiu Chiriac, Yohann Renard, Emilie Raimond, Marie Laurence Poli-Merol, Benoit Chaput, Caroline François
Background: Morphometric and anatomical analyses of the shape and position of the umbilicus have been conducted in adults, but umbilicoplasty in children remains challenging because growth is still occurring. Objectives: The main objective of this study was to evaluate the difference in the position and shape of the umbilicus between childhood and adulthood. The secondary objective was to improve the surgical management of umbilicoplasty in children. Methods: This prospective single-center study focused on the morphometric analysis of the umbilicus in 200 adults and children...
November 8, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29124248/circumcision-incision-orchidopexy-a-novel-technique-for-palpable-low-inguinal-undescended-testis
#8
Michael E Chua, Jan Michael A Silangcruz, Odina Gomez, Jun S Dy, Marcelino L Morales
Given that both orchidopexy and circumcision are commonly done in a single operative setting, we adopted a technique of combined orchidopexy and circumcision using a single circumcision incision. We applied this new technique to boys with palpable, low inguinal cryptorchidism. Here we describe a case series of 7 boys who underwent concurrent orchidopexy via the circumcision site. We present this novel technique and discuss our preliminary outcomes, including the anatomic basis and feasibility. The technique appears to be an alternative for concurrent circumcision and cryptorchid cases with palpable, low inguinal testes...
November 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29124038/intraoperative-radiation-for-breast-cancer-with-intrabeam%C3%A2-factors-associated-with-decreased-operative-times-in-patients-having-iort-for-breast-cancer
#9
Stephanie A Valente, Alicia Fanning, Robyn A Stewart, Sharon Grundfest, Rahul D Tendulkar, Sheen Cherian, Chirag Shah, Chao Tu, Courtney Yanda, Diane Radford, Zahraa Al-Hilli, Stephen R Grobmyer
Introduction: Intraoperative radiation with Intrabeam™ (IORT) for breast cancer is a newer technology recently implemented into the operating room (OR). This procedure requires time and coordination between the surgeon and radiation oncologist, who both perform their treatments in a single operative setting. We evaluated the surgeons at our center, who perform IORT and their OR times to examine changes in OR times following implementation of this new surgical procedure. We hypothesized that IORT is a technique for which timing could be improved with the increasing number of cases performed...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/29117417/repeatability-of-a-commercially-available-adaptive-optics-visual-simulator-and-aberrometer-in-normal-and-keratoconic-eyes
#10
Rohit Shetty, Shruti Kochar, Tushar Grover, Pooja Khamar, Pallak Kusumgar, Kanchan Sainani, Abhijit Sinha Roy
PURPOSE: To evaluate the repeatability of aberration measurement obtained by a Hartmann-Shack aberrometer combined with a visual adaptive optics simulator in normal and keratoconic eyes. METHODS: One hundred fifteen normal eyes and 92 eyes with grade I and II keratoconus, as per the Amsler-Krumeich classification, were included in the study. To evaluate the repeatability, three consecutive measurements of ocular aberrations were obtained by a single operator. Zernike analyses up to the 5th order for a pupil size of 4...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29107445/-apple-far-from-the-tree-comparative-effectiveness-of-fiberoptic-single-operator-cholangiopancreatoscopy-fsocp-and-digital-socp-dsocp
#11
Meir Mizrahi, Tawfik Khoury, Yan Wang, Jonah Cohen, Jennifer Sheridan, Ram Chuttani, Tyler M Berzin, Mandeep S Sawhney, Douglas K Pleskow
BACKGROUND: While the fiberoptic single-operator cholangiopancreatoscopy (FSOCP) system has demonstrated efficacy in the diagnosis and management of pancreaticobiliary diseases, the digital SOCP (DSOCP) appears to provide higher resolution digital imaging, however a comparison of these devices has not been established. The aim of this work was to compare the efficacy of FSOCP and DSOCP in biliary stone disease and indeterminate biliary strictures. METHODS: A retrospective analysis of a prospective cohort was performed in patients undergoing FSOCP or DSOCP demographics included indication, diagnostic yield, procedure time, radiation dose, and complications...
October 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29105882/iron-catalyzed-hydroborylative-cyclization-of-1-6-enynes
#12
Diego J Cardenas, Natalia Cabrera-Lobera, Patricia Rodríguez-Salamanca, Juan Carlos Nieto-Carmona, Elena Buñuel
We report first Fe-catalyzed hydroborylative cyclization reaction. The process provides one C-C and one C-B bond in a single operation and shows a wide scope, allowing the formation of carbo- and heterocycles containing a homoallylic boryl unit that can be further functionalized. The reaction takes place in smooth conditions, with inexpensive catalytic system and full atom economy since HBpin is the borylation agent, in contrast to our previously reported Pd-catalyzed reaction. Both aryl and alkyl substituted alkynes are reactive, revealing a wide reaction scope...
November 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29101555/mivat-the-last-2-years-experience-tips-and-techniques-after-more-than-10-years
#13
C Bellotti, M Giulii Capponi, M Cinquepalmi, G Castagnola, S Marchetta, F Mallozzi, M Pezzatini, A Brescia
BACKGROUND: Minimally invasive video-assisted thyroidectomy (MIVAT) has been introduced into clinical practice by Miccoli in the late 1990s (Miccoli et al., Am J Surg 181(6):567-570, 2001) and it has become a widespread technique used and welcomed worldwide. In this paper, we present our experience of the last 2 years; we also describe tips and techniques derived from over 460 cases performed in the last 10 years by the same surgical team with the same single operator. METHODS: In the last 10 years, we did about 460 MIVAT procedures...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29100213/pose-inspired-shape-synthesis-and-functional-hybrid
#14
Qiang Fu, Xiaowu Chen, Xiaoyu Su, Hongbo Fu
We introduce a shape synthesis approach especially for functional hybrid creation that can be potentially used by a human operator under a certain pose. Shape synthesis by reusing parts in existing models has been an active research topic in recent years. However, how to combine models across different categories to design multi-function objects remains challenging, since there is no natural correspondence between models across different categories. We tackle this problem by introducing a human pose to describe object affordance which establishes a bridge between cross-class objects for composite design...
December 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/29078996/ambulatory-unicompartmental-knee-arthroplasty-short-outcome-of-50-first-cases
#15
N Ruiz, X Buisson, G Filippi, M Roulet, H Robert
INTRODUCTION: The reduction in length of stay (LOS) in orthopaedic surgery has been steady for several years. For the past 3 or 4 years in France, the trend towards outpatient surgery has been growing up, as it is a goal for hospital administration. MATERIALS AND METHODS: This is a prospective, continuous,mono-centric, single operator study on 56 UKAs. Included were all UKAs carried out between January 2014 and December 2015, meeting the following criteria: voluntary patients, supportive family environment, absence of comorbidity (oral anticoagulants, diabetes, obesity), ASA score ≤ 3...
October 24, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29077584/comfort-ocular-dryness-and-equilibrium-water-content-changes-of-daily-disposable-contact-lenses
#16
Eduardo Insua Pereira, Madalena Lira
OBJECTIVES: The objective of this investigation was to evaluate the level of comfort and ocular dryness during wear with six daily disposable contact lenses (DDCL) and also determine the changes in contact lens equilibrium water content (EWC) resulting from their wear. METHODS: In this contralateral open trial, 27 subjects were randomly fitted with six DDCL (stenfilcon A, delefilcon A, nelfilcon A, narafilcon A, nesofilcon A, and omafilcon A). The evaluation of comfort and ocular dryness sensation was recorded by the participants at two moments of the day (11 AM and 5 PM) over a period of 10 days of contact lens wear...
October 26, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29077189/gentle-endodiathermy-of-retinal-vessels-to-mark-paravascular-posterior-retinal-breaks-in-highly-myopic-eyes
#17
Giuseppe D'Amico Ricci, Antonio Pinna, Francesco Boscia, Giancarlo Sborgia, Ermete Giancipoli
PURPOSE: To show a new method to highlight posterior paravascular retinal breaks, responsible for posterior retinal detachment in highly myopic eyes, by gentle endodiathermy on the nearby retinal vessel, in areas of patchy chorioretinal atrophy. METHODS: A standard 25-gauge (25-G) 3-port pars plana vitrectomy with internal limiting membrane (ILM) peeling was performed. A gentle endodiathermy was applied on the vessel close to the retinal break until a clear withe spot became visible...
October 16, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29076738/copper-catalyzed-azidative-multifunctionalization-of-alkynes
#18
Guangfan Zheng, Jiaqiong Sun, Yang Liu, Shengbiao Yang, Yan Li, Haizhu Sun, Qian Zhang
A facile and efficient copper-catalyzed azidative multifunctionalization of alkynes has been developed by using N-fluorobenzenesulfonimide (NFSI) as both nitrogen source and aryl source and trimethylsilyl azide (TMSN3) as azido source. This transformation proceeds under mild conditions, providing a series of α-azido-α-aryl imine in good yields by a single operation starting from a wide range of alkynes. The prepared α-azido-α-aryl imines could be easily converted into 1,5-piperizine-fused 1,2,3-triazoles and azido enamines...
November 8, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29075526/supravalvar-mitral-ring-with-a-parachute-mitral-valve-and-subcoarctation-of-the-aorta-in-a-child-with-hemodynamically-significant-vsd-a-study-of-the-morphology-echocardiographic-diagnostics-and-surgical-therapy
#19
Wojciech Mądry, Maciej A Karolczak, Krzysztof Grabowski
The authors present a case of echocardiographic diagnosis of supravalvar mitral ring (a fibromembranous structure that arose from the atrial surface of the mitral leaflets) in a child with a parachute mitral valve, a ventricular septal defect, and mild narrowing of the aortic isthmus. The supravalvar mitral stenosis is a typical but very infrequently detected element of the complex of anatomical abnormalities located within the left heart and the proximal aorta, called the Shone's complex (syndrome). Diagnosing an additional, hemodynamically significant anatomic defect during echocardiography was possible thanks to the detection of marked mobility limitation of the ring-adjacent part of the mitral valve mural leaflet as well as of an atypical image of turbulence occurring during the inflow from the left atrium to the left ventricle...
September 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29074446/efficacy-and-safety-of-digital-single-operator-cholangioscopy-for-difficult-biliary-stones
#20
Olaya I Brewer Gutierrez, Noor L H Bekkali, Isaac Raijman, Richard Sturgess, Divyesh V Sejpal, Hanaa D Aridi, Stuart Sherman, Raj J Shah, Richard S Kwon, James L Buxbaum, Claudio Zulli, Wahid Wassef, Douglas G Adler, Vladimir Kushnir, Andrew Y Wang, Kumar Krishnan, Vivek Kaul, Demetrios Tzimas, Christopher J DiMaio, Sammy Ho, Bret Petersen, Jong Ho Moon, B Joseph Elmunzer, George J M Webster, Yen-I Chen, Laura K Dwyer, Summant Inamdar, Vanessa B Patrick, Augustin Attwell, Amy Hosmer, Christopher Ko, Attilio Maurano, Avik Sarkar, Linda J Taylor, Martin H Gregory, Daniel S Strand, Ali Raza, Shivangi Kothari, Jessica P Harris, Nikhil A Kumta, Amar Manvar, Mark D Topazian, Yun Nah Lee, Clayton M Spiceland, Majidah A Bukhari, Omid Sanaei, Saowanee Ngamruengphong, Mouen A Khashab
BACKGROUND & AIMS: It is not clear whether digital single-operator cholangioscopy (D-SOC) with electrohydraulic and laser lithotripsy is effective in removal of difficult biliary stones. We investigated the safety and efficacy of D-SOC with electrohydraulic and laser lithotripsy in an international, multicenter study of patients with difficult biliary stones. METHODS: We performed a retrospective analysis of 407 patients (60.4% female; mean age, 64.2 years) who underwent D-SOC for difficult biliary stones at 22 tertiary centers in the United States, United Kingdom, or Korea from February 2015 through December 2016; 306 patients underwent electrohydraulic lithotripsy and 101 (24...
October 24, 2017: Clinical Gastroenterology and Hepatology
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