Brent M Roeder, Xiwei She, Alexander S Dakos, Bryan Moore, Robert T Wicks, Mark R Witcher, Daniel E Couture, Adrian W Laxton, Heidi Munger Clary, Gautam Popli, Charles Liu, Brian Lee, Christianne Heck, George Nune, Hui Gong, Susan Shaw, Vasilis Z Marmarelis, Theodore W Berger, Sam A Deadwyler, Dong Song, Robert E Hampson
OBJECTIVE: Here, we demonstrate the first successful use of static neural stimulation patterns for specific information content. These static patterns were derived by a model that was applied to a subject's own hippocampal spatiotemporal neural codes for memory. APPROACH: We constructed a new model of processes by which the hippocampus encodes specific memory items via spatiotemporal firing of neural ensembles that underlie the successful encoding of targeted content into short-term memory...
2024: Frontiers in Computational Neuroscience