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https://www.readbyqxmd.com/read/28523827/statistical-model-based-hplc-analytical-method-adjustment-strategy-to-adapt-to-different-sets-of-analytes-in-complicated-samples
#1
Binjun Yan, Xue Bai, Yunjie Sheng, Fanzhu Li
INTRODUCTION: On account of the complicated compositions of the products like traditional Chinese medicines (TCMs) and functional foods, it is a common practice to determine different sets of analytes in the same product for different purposes. OBJECTIVE: To efficiently develop the corresponding HPLC methods, a statistical model based analytical method adjustment (SMB-AMA) strategy was proposed. METHODS: In this strategy, the HPLC data acquired with design of experiments methodology were efficiently utilised to build the retention models for all the analytes and interferences shown in the chromatograms with multivariate statistical modelling methods...
May 19, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28509654/clinical-reasoning-embodied-meaning-making-in-physiotherapy
#2
Anoop Chowdhury, Wenche Schrøder Bjorbækmo
This article examines physiotherapists' lived experience of practicing physiotherapy in primary care, focusing on clinical reasoning and decision-making in the case of a patient we call Eva. The material presented derives from a larger study involving two women participants, both with a protracted history of neck and shoulder pain. A total of eight sessions, all of them conducted by the first author, a professional physiotherapist, in his own practice room, were videotaped, after which the first author transcribed the sessions and added reflective notes...
May 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28472050/empirically-characteristic-analysis-of-chaotic-pid-controlling-particle-swarm-optimization
#3
Danping Yan, Yongzhong Lu, Min Zhou, Shiping Chen, David Levy
Since chaos systems generally have the intrinsic properties of sensitivity to initial conditions, topological mixing and density of periodic orbits, they may tactfully use the chaotic ergodic orbits to achieve the global optimum or their better approximation to given cost functions with high probability. During the past decade, they have increasingly received much attention from academic community and industry society throughout the world. To improve the performance of particle swarm optimization (PSO), we herein propose a chaotic proportional integral derivative (PID) controlling PSO algorithm by the hybridization of chaotic logistic dynamics and hierarchical inertia weight...
2017: PloS One
https://www.readbyqxmd.com/read/28394483/corticobulbar-projections-from-distinct-motor-cortical-areas-to-the-reticular-formation-in-macaque-monkeys
#4
Michela Fregosi, Alessandro Contestabile, Adjia Hamadjida, Eric M Rouiller
Corticospinal and corticobulbar descending pathways act in parallel with brainstem systems, such as the reticulospinal tract, to ensure the control of voluntary movements via direct or indirect influences onto spinal motoneurons. The aim of this study was to investigate the corticobulbar projections from distinct motor cortical areas onto different nuclei of the reticular formation. Seven adult macaque monkeys were analysed for the location of corticobulbar axonal boutons, and one monkey for reticulospinal neurons' location...
April 10, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28388222/clinician-guided-assessment-of-personality-using-the-structural-interview-and-the-structured-interview-of-personality-organization-stipo
#5
Susanne Hörz-Sagstetter, Eve Caligor, Emanuele Preti, Barry L Stern, Chiara De Panfilis, John F Clarkin
This article demonstrates the utility of a theory-guided psychodynamic approach to the assessment of personality and personality pathology based on the object relations model developed by Kernberg (1984). We describe a clinical interview, the Structural Interview (SI; Kernberg, 1984), and also a semistructured approach, the Structured Interview of Personality Organization (STIPO; Clarkin, Caligor, Stern, & Kernberg, 2004) based on this theoretical model. Both interviews focus on the assessment of consolidated identity versus identity disturbance, the use of adaptive versus lower level defensive operations, and intact versus loss of reality testing...
April 7, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28278473/optimal-external-wrench-distribution-during-a-multi-contact-sit-to-stand-task
#6
Vincent Bonnet, Christine Azevedo Coste, Thomas Robert, Philippe Fraisse, Gentiane Venture
This study aims at developing and evaluating a new practical method for the real-time estimate of joint torques and external wrenches during multi-contact sit-to-stand task using kinematics data only. The proposed method allows also identifying subject specific body inertial segment parameters that are required to perform inverse dynamics. The identification phase is performed using simple and repeatable motions. Thanks to an accurately identified model the estimate of the total external wrench can be used as an input to solve an under-determined multi-con-tact problem...
March 1, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28272639/recent-advances-in-the-overman-rearrangement-synthesis-of-natural-products-and-valuable-compounds
#7
REVIEW
Rodney A Fernandes, Pullaiah Kattanguru, Sachin P Gholap, Dipali A Chaudhari
In the past decade, the Overman rearrangement, an important C-N bond forming reaction, has been intensely used in the synthesis of natural products, synthetic intermediates, building blocks and valuable compounds. This review documents the reports on this rearrangement reaction since 2005. The reaction has been tactfully used to introduce amine functionality in the synthesis of natural products. It is a one-pot process using the intermediate imidate which upon rearrangement generates the amide that can be hydrolysed to the amine...
March 8, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28243540/retrospective-observation-of-drug-susceptibility-of-candida-strains-in-the-years-1999-2004-and-2015
#8
Cecylia Łukaszuk, Elżbieta Krajewska-Kułak, Wojciech Kułak
INTRODUCTION: There is much literature devoted to the problem of drug resistance and decreased susceptibility of fungi to commonly used antifungals. AIM: To analyze drug susceptibility of Candida albicans and non-Candida albicans strains isolated from the hands of people without any symptoms of disease over a 16-year period. MATERIALS AND METHODS: The study included a total of 1,274 Candida-type strains isolated from the hands of people without any symptoms of disease, including: in 1999, 432 strains; in 2004, 368; and in 2015, 454 strains...
2017: PeerJ
https://www.readbyqxmd.com/read/28239409/iroa-international-register-of-open-abdomen-preliminary-results
#9
Federico Coccolini, Giulia Montori, Marco Ceresoli, Fausto Catena, Rao Ivatury, Michael Sugrue, Massimo Sartelli, Paola Fugazzola, Davide Corbella, Francesco Salvetti, Ionut Negoi, Monica Zese, Savino Occhionorelli, Stefano Maccatrozzo, Sergei Shlyapnikov, Christian Galatioto, Massimo Chiarugi, Zaza Demetrashvili, Daniele Dondossola, Yovcho Yovtchev, Orestis Ioannidis, Giuseppe Novelli, Mirco Nacoti, Desmond Khor, Kenji Inaba, Demetrios Demetriades, Torsten Kaussen, Asri Che Jusoh, Wagih Ghannam, Boris Sakakushev, Ohad Guetta, Agron Dogjani, Stefano Costa, Sandeep Singh, Dimitrios Damaskos, Arda Isik, Kuo-Ching Yuan, Francesco Trotta, Stefano Rausei, Aleix Martinez-Perez, Giovanni Bellanova, Vinicius Cordeiro Fonseca, Fernando Hernández, Athanasios Marinis, Wellington Fernandes, Martha Quiodettis, Miklosh Bala, Andras Vereczkei, Rafael L Curado, Gustavo Pereira Fraga, Bruno M Pereira, Mahir Gachabayov, Guillermo Perez Chagerben, Miguel Leon Arellano, Sefa Ozyazici, Gianluca Costa, Tugan Tezcaner, Luca Ansaloni
BACKGROUND: No definitive data about open abdomen (OA) epidemiology and outcomes exist. The World Society of Emergency Surgery (WSES) and the Panamerican Trauma Society (PTS) promoted the International Register of Open Abdomen (IROA). METHODS: A prospective observational cohort study including patients with an OA treatment. Data were recorded on a web platform (Clinical Registers®) through a dedicated website: www.clinicalregisters.org. RESULTS: Four hundred two patients enrolled...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28211940/instructive-feedback-embedded-within-group-instruction-for-children-diagnosed-with-autism-spectrum-disorder
#10
Justin B Leaf, Joseph H Cihon, Aditt Alcalay, Erin Mitchell, Donna Townley-Cochran, Kevin Miller, Ronald Leaf, Mitchell Taubman, John McEachin
The present study evaluated the effects of instructive feedback embedded within a group discrete trial teaching to teach tact relations to nine children diagnosed with autism spectrum disorder using a nonconcurrent multiple-baseline design. Dependent variables included correct responses for: primary targets (directly taught), secondary targets (taught via instructive feedback), primary observational targets (directly taught to other members of the group), and secondary observational targets (taught via instructive feedback provided to other members of the group)...
April 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/28187519/development-of-a-novel-alginate-polyvinyl-alcohol-hydroxyapatite-hydrogel-for-3d-bioprinting-bone-tissue-engineered-scaffolds
#11
Stephanie T Bendtsen, Sean P Quinnell, Mei Wei
Three-dimensional printed biomaterials used as personalized tissue substitutes have the ability to promote and enhance regeneration in areas of defected tissue. The challenge with 3D printing for bone tissue engineering remains the selection of a material with optimal rheological properties for printing in addition to biocompatibility and capacity for uniform cell incorporation. Hydrogel biomaterials may provide sufficient printability to allow cell encapsulation and bioprinting of scaffolds with uniform cell distribution...
May 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28145862/vegf-mediated-signaling-in-oral-cancer
#12
REVIEW
X Lin, S Khalid, M Z Qureshi, R Attar, I Yaylim, I Ucak, A Yaqub, S Fayyaz, A A Farooqi, M Ismail
Increasingly it is being realized that oral cancer arises from genetic/epigenetic mutations, dysregulations of spatio-temporally controlled signal transduction cascades and loss of apoptosis. Epidemiological studies have provided a stronger association between tobacco use (chewed and smoked) and oral cancer. Nevertheless, alcohol has also gained attention as a significant risk factor, having a multiplicative synergistic cancer promoting effect with tobacco. Vascular Endothelial Growth Factor (VEGF) mediated signaling has gained limelight because of its instrumental role in endothelial cell proliferation, survival, invasion, migration, chemotaxis of bone marrow (BM)-derived progenitor cells, vasodilation and vascular permeability...
December 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28128451/teaching-complex-verbal-operants-to-children-with-autism-and-establishing-generalization-using-the-peak-curriculum
#13
Mark R Dixon, Jacqueline Peach, Jacob H Daar, Cindy Penrod
The present study evaluated the feasibility of the PEAK Relational Training System's Generalization Module (Dixon, 2014b) to teach and establish generalization of autoclitic mands, distorted tacts, and creative path finding in three children diagnosed with autism spectrum disorder. Using a multiple-baseline design across behaviors, each participant was provided with differential reinforcement and a least-to-most prompting hierarchy for correct responses to a subset of stimuli, and responses to other similar stimulus sets were probed for emergent generalization...
January 27, 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/28101892/an-assessment-of-differential-reinforcement-procedures-for-learners-with-autism-spectrum-disorder
#14
Kate A Johnson, Jason C Vladescu, Tiffany Kodak, Tina M Sidener
Differential reinforcement procedures may promote unprompted correct responding, resulting in a quicker transfer of stimulus control than nondifferential reinforcement. Recent studies that have compared reinforcement arrangements have found that the most effective arrangement may differ across participants. The current study conducted an assessment of differential reinforcement arrangements (i.e., quality, schedule, and magnitude) and nondifferential reinforcement to identify the most effective arrangement for each participant...
January 19, 2017: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/28064477/fast-optimization-of-limgmnox-la2o3-catalysts-for-the-oxidative-coupling-of-methane
#15
Zhinian Li, Lei He, Shenliang Wang, Wuzhong Yi, Shihui Zou, Liping Xiao, Jie Fan
The development of efficient catalyst for oxidative coupling of methane (OCM) reaction represents a grand challenge in direct conversion of methane into other useful products. Here, we reported that a newly developed combinatorial approach can be used for ultrafast optimization of La2O3-based multicomponent metal oxide catalysts in OCM reaction. This new approach integrated inkjet printing assisted synthesis (IJP-A) with multidimensional group testing strategy (m-GT) tactfully takes the place of conventionally high-throughput synthesis-and-screen experiment...
January 9, 2017: ACS Combinatorial Science
https://www.readbyqxmd.com/read/28024393/boron-precursor-dependent-evolution-of-differently-emitting-carbon-dots
#16
Jayasmita Jana, Mainak Ganguly, Kuttay R S Chandrakumar, Gowravaram Mohan Rao, Tarasankar Pal
Attention has been directed toward electron-deficient boron doping in carbon dots (CDs) with the expectation of revealing new photophysical aspects in accordance with varying amounts of boron content. It has been emphatically shown that boron uptake in CDs varies with different boron precursors evolving altered emissive CDs. Boron doping in CDs causes definite surface defect due to the generation of electron-deficient states. Modified hydrothermal treatment of a mixture of ascorbic acid (AA) and different boron precursor compounds (borax/boric acid/sodium borate/sodium borohydride) produces different kinds of boron-doped CDs (BCDs)...
January 6, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28003154/antipsychotics-influence-toll-like-receptor-tlr-expression-and-its-relationship-with-cognitive-functions-in-schizophrenia
#17
Szabolcs Kéri, Csilla Szabó, Oguz Kelemen
Increasing evidence suggests that altered immune functions are related to the pathophysiology of schizophrenia. Relatively little information is available on Toll-like receptors (TLRs), which are implicated in the recognition of molecular patterns associated with pathogens and internal cellular damage signals. By using immunophenotyping and flow cytometry, we investigated TLRs in CD14+ monocytes, CD4+CD25+Foxp3+ regulatory T cells (Treg), and CD3+CD4+CD25+ activated T cells (Tact) in 35 drug-naïve patients with schizophrenia before and after an 8-week period of antipsychotic treatment with risperidone or olanzapine...
December 19, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27986738/african-american-patients-with-cancer-talking-about-clinical-trials-tact-with-oncologists-during-consultations-evaluating-the-efficacy-of-tailored-health-messages-in-a-randomised-controlled-trial-the-tact-study-protocol
#18
R F Brown, R Davis, M Wilson Genderson, S Grant, D Cadet, M Lessard, J Alpert, J Ward, G Ginder
INTRODUCTION: Low rates of accrual of African-American (AA) patients with cancer to therapeutic clinical trials (CTs) represent a serious and modifiable racial disparity in healthcare that impedes the development of promising cancer therapies. Suboptimal physician-patient consultation communication is a barrier to the accrual of patients with cancer of any race, but communication difficulties are compounded with AA patients. Providing tailored health messages (THM) to AA patients and their physician about CTs has the potential to improve communication, lower barriers to accrual and ameliorate health disparities...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27903998/survival-benefit-of-hemodiafiltration-compared-with-prolonged-high-flux-hemodialysis
#19
Petar S Djuric, Aleksandar Jankovic, Jovan Popovic, Jelena Tosic Dragovic, Ana Bulatovic, Zivka Djuric, Milos Mitrovic, Nada Dimkovic
INTRODUCTION:  Patients on dialysis have a high rate of death, mainly of cardiovascular cause. Nephrologists are actively looking for ways to improve patients' outcomes, and alternative dialysis strategies, such as long conventional hemodialysis and hemodiafiltration, are currently being investigated. The aim of this study was to compare anemia, nutrition, inflammation, mineral metabolism, and 3-year survival rates between patients treated with hemodiafiltration and prolonged high-flux hemodialysis (HFH)...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27893901/the-lived-experience-of-nursing-faculty-in-a-dedicated-education-unit
#20
Deborah A DeMeester
BACKGROUND: The dedicated education unit (DEU) was developed as an innovation to increase enrollment capacity and secure stable clinical placement sites in units that provide an optimal learning environment. The purpose of this multisite study was to describe, interpret, and offer insight into the meanings of the lived experiences of nursing faculty who had transitioned to teaching in a DEU. METHOD: Semistructured private interviews were conducted using an interpretive phenomenological approach...
December 1, 2016: Journal of Nursing Education
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