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https://www.readbyqxmd.com/read/28968211/h2o2-sensing-through-electrochemically-deposited-thionine-coated-ito-thin-film
#1
P Singh, S Srivastava, S K Singh
Progression and initiation of different diseases including pulmonary diseases, alzheimer's and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in detoxifying reactive oxygen species including hydrogen peroxide (H2O2) that is generated in response to various stimuli and has important role in cell activation & bio-signaling processes. Herein, we developed hydrogen peroxide electrochemical sensor based on horseradish peroxidase (HRP) entrapped polymerized thionine (PTH) film...
July 31, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28956154/sources-of-interference-in-cross-modal-action-response-selection-crosstalk-and-general-dual-execution-costs
#2
Aleks Pieczykolan, Lynn Huestegge
Performing several actions simultaneously usually yields interference, which is commonly explained by referring to theoretical concepts such as crosstalk and structural limitations associated with response selection. While most research focuses on dual-task scenarios (involving two independent tasks), we here study the role of response selection and crosstalk for the control of cross-modal response compounds (saccades and manual responses) triggered by a single stimulus. In two experiments, participants performed single responses and spatially compatible versus incompatible dual-response compounds (crosstalk manipulation) in conditions with or without response selection requirements (i...
September 27, 2017: Psychological Research
https://www.readbyqxmd.com/read/28926026/conceptual-models-underlying-economic-analysis-of-animal-health-and-welfare-with-the-inclusion-of-three-components-people-products-and-resources
#3
D A Hennessy
Infectious animal diseases can spill across farm boundaries, so effective management requires coordinated responses. Costs and benefits from the management of infectious diseases are such that those who make the decisions have weak incentives to act, the levels of goods and services produced from animal agriculture are probably smaller than is socially optimal and resources are likely wasted. This work provides an overview of the existing literature on conceptual economic models in animal disease management, paying particular attention to inadequate incentives to make the required biosecurity efforts...
April 2017: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28894554/exploring-the-adaptive-experiences-of-children-with-parents-of-myocardial-infarction-a-qualitative-study
#4
Tahere Hashemifard, Ali Akbar Vaezi, Seyed Saeed Mazloomy, Tahere Kamalikhah, Mehdi Khankolabi, Abbas Andishmand, Mohammad Hossein Baghianimoghadam
BACKGROUND: Cardiovascular diseases are the world's leading cause of mortality. These diseases are rooted in an unhealthy lifestyle. In order to confront this subject, it is essential to identify several risk factors that contribute to heart disease (HD) in people with different attitudes, values, beliefs, expectations and motivations. This study was therefore an attempt to explain the adaptive experiences of children whose parents were involved in myocardial infarction since they were more likely subjected to get the so-called disease...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28832876/addiction-potential-of-cigarettes-with-reduced-nicotine-content-in-populations-with-psychiatric-disorders-and-other-vulnerabilities-to-tobacco-addiction
#5
RANDOMIZED CONTROLLED TRIAL
Stephen T Higgins, Sarah H Heil, Stacey C Sigmon, Jennifer W Tidey, Diann E Gaalema, John R Hughes, Maxine L Stitzer, Hanna Durand, Janice Y Bunn, Jeff S Priest, Christopher A Arger, Mollie E Miller, Cecilia L Bergeria, Danielle R Davis, Joanna M Streck, Derek D Reed, Joan M Skelly, Lauren Tursi
Importance: A national policy is under consideration to reduce the nicotine content of cigarettes to lower nicotine addiction potential in the United States. Objective: To examine how smokers with psychiatric disorders and other vulnerabilities to tobacco addiction respond to cigarettes with reduced nicotine content. Design, Setting, and Participants: A multisite, double-blind, within-participant assessment of acute response to research cigarettes with nicotine content ranging from levels below a hypothesized addiction threshold to those representative of commercial cigarettes (0...
October 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28749603/protection-motivation-theory-in-predicting-intention-to-receive-cervical-cancer-screening-in-rural-chinese-women
#6
Yang Bai, Qing Liu, Xinguang Chen, Yanduo Gao, Huiyun Gong, Xiaodong Tan, Min Zhang, Jiyu Tuo, Yuling Zhang, Qunying Xiang, Fenghua Deng, Guiling Liu
OBJECTIVE: Despite the significance of cervical cancer screening, motivating more women to participate remains a challenge in resource-limited settings. In this study, we tested the protection motivation theory (PMT) in predicting screening intentions. METHODS: Participants were women from Wufeng, a typical rural county in China. Participants (n=3000) with no cervical cancer history were recruited from 10 randomly selected villages. As mediating variables, six PMT constructs (Perceived Risk, Fear Arousal, Perceived Severity, Response Efficacy, Response Cost and Self-Efficacy) were measured using the standardized questionnaire...
July 27, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28747679/gambling-like-behavior-in-pigeons-jackpot-signals-promote-maladaptive-risky-choice
#7
Aaron P Smith, Joshua S Beckmann, Thomas R Zentall
Individuals often face choices that have uncertain outcomes and have important consequences. As a model of this environment, laboratory experiments often offer a choice between an uncertain, large reward that varies in its probability of delivery against a certain but smaller reward as a measure of an individual's risk aversion. An important factor generally lacking from these procedures are gambling related cues that may moderate risk preferences. The present experiment offered pigeons choices between unreliable and certain rewards but, for the Signaled group on winning choices, presented a 'jackpot' signal prior to reward delivery...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28737025/-influence-of-initial-protocolized-treatment-with-steroids-in-length-of-stay-and-costs-of-community-acquired-pneumonia
#8
J Gómez Gómez, J L Gómez Torres, A Hernández Torres, J A García Córdoba, M Canteras Jordana
OBJECTIVE: The aim of the study was to analyze the impact of steroid treatment in patients with community acquired pneumonia (CAP), both in length of stay and economical cost of admission at a clinical university hospital. METHODS: Prospective study of admitted patients with the diagnosis of CAP, both in Internal Medicine and Infectious diseases department. The study was conducted from January to march 2015; patients receiving steroids from diagnosis to end of antibiotic treatment were classified as group I; otherwise, they were considered in group II...
July 24, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28716966/hierarchically-organized-medial-frontal-cortex-basal-ganglia-loops-selectively-control-task-and-response-selection
#9
Franziska M Korb, Jiefeng Jiang, Joseph A King, Tobias Egner
Adaptive behavior requires context-sensitive configuration of task-sets that specify time-varying stimulus-response mappings. Intriguingly, response time costs associated with changing task-sets and motor responses are known to be strongly interactive: switch costs at the task level are small in the presence of a response-switch but large when accompanied by a response-repetition, and vice versa for response-switch costs. The reasons behind this well known interdependence between task- and response-level control processes are currently not well understood...
August 16, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28469437/predicting-adherence-to-aromatase-inhibitor-therapy-among-breast-cancer-survivors-an-application-of-the-protection-motivation-theory
#10
Monita Karmakar, Sharrel L Pinto, Timothy R Jordan, Iman Mohamed, Monica Holiday-Goodman
The purpose of this observational study was to determine if the Protection Motivation Theory could predict and explain adherence to aromatase inhibitor (AI) therapy among breast cancer survivors. Purposive sampling was used to identify 288 survivors who had been prescribed AI therapy. A valid and reliable survey was mailed to survivors. A total of 145 survivors completed the survey. The Morisky scale was used to measure adherence to AI. The survivors reported a mean score of 6.84 (±0.66) on the scale. Nearly 4 in 10 survivors (38%) were non-adherent...
2017: Breast Cancer: Basic and Clinical Research
https://www.readbyqxmd.com/read/28467688/effectiveness-and-cost-of-hepatitis-c-virus-cryoglobulinaemia-vasculitis-treatment-from-interferon-based-to-direct-acting-antivirals-era
#11
Patrice Cacoub, Mathieu Vautier, Anne Claire Desbois, Antoine Lafuma, David Saadoun
BACKGROUND: The net benefits of new hepatitis C virus (HCV) direct-acting antiviral drugs (DAA) in patients with cryoglobulinaemia vasculitis (CryoVas) are unknown. OBJECTIVE: To analyse the effectiveness and cost of all treatments used for HCV-CryoVas in the DAA vs pre-DAA era. METHODS: A chart review of all HCV-CryoVas patients who received antivirals from 1993 to 2016 in a tertiary centre was performed. Treatment effectiveness was analysed for clinical, immunological and virological responses...
May 3, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28439249/cross-modal-action-complexity-action-and-rule-related-memory-retrieval-in-dual-response-control
#12
Aleks Pieczykolan, Lynn Huestegge
Normally, we do not act within a single effector system only, but rather coordinate actions across several output modules (cross-modal action). Such cross-modal action demands can vary substantially with respect to their complexity in terms of the number of task-relevant response combinations and to-be-retrieved stimulus-response (S-R) mapping rules. In the present study, we study the impact of these two types of cross-modal action complexity on dual-response costs (i.e., performance differences between single- and dual-action demands)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28131395/an-expensive-adult-measles-outbreak-and-response-in-office-buildings-during-the-era-of-accelerated-measles-elimination-beijing-china
#13
Rui Ma, Li Lu, Luodan Suo, Xiaomei Li, Fan Yang, Tao Zhou, Lijun Zhai, Hongwei Bai, Xinghuo Pang
BACKGROUND: Few measles outbreaks among adults are reported in China, and outbreak response costs are seldom documented. We report an adult measles outbreak and response in 4 linked office buildings in Beijing and its associated costs. METHOD: The World Health Organization measles case definitions were used to determine suspected and confirmed measles cases. Surveillance data were used to describe the outbreak, and records and interviews of response staff were used to describe the response...
February 22, 2017: Vaccine
https://www.readbyqxmd.com/read/27986195/interchangeability-between-pneumococcal-conjugate-vaccines-a-systematic-review-and-meta-analysis
#14
REVIEW
Agustín Ciapponi, Alison Lee, Ariel Bardach, Demián Glujovsky, Lucila Rey-Ares, María Luisa Cafferata, Pilar Valanzasca, Sebastián García Martí
OBJECTIVES: To assess the efficacy, cost-effectiveness, immunogenicity, and safety related to the interchangeability between pneumococcal conjugate vaccines (PCVs) and vaccination schedules in pediatric population. METHODS: Systematic searches were conducted in December 2010 and April 2015 for economic evaluations in MEDLINE, EMBASE, LILACS, and Cochrane Central Register of Controlled Trials. Web sites and databases from medical societies, experts, and associations related to the topic, proceedings or congressional annals, and doctoral theses were also searched...
December 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27960067/do-patients-and-oncologists-discuss-the-cost-of-cancer-treatment-an-observational-study-of-clinical-interactions-between-african-american-patients-and-their-oncologists
#15
Lauren M Hamel, Louis A Penner, Susan Eggly, Robert Chapman, Justin F Klamerus, Michael S Simon, Sarah C E Stanton, Terrance L Albrecht
PURPOSE: Financial toxicity negatively affects patients with cancer, especially racial/ethnic minorities. Patient-oncologist discussions about treatment-related costs may reduce financial toxicity by factoring costs into treatment decisions. This study investigated the frequency and nature of cost discussions during clinical interactions between African American patients and oncologists and examined whether cost discussions were affected by patient sociodemographic characteristics and social support, a known buffer to perceived financial stress...
March 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27912857/homelessness-and-aging-the-contradictory-ordering-of-house-and-home
#16
Amanda Grenier, Rachel Barken, Colleen McGrath
The concepts of 'house' and 'home' are compelling and contradictory. They are compelling because they elicit the desired sentiments of permanence, feeling 'at home', and maintaining continuity in one's life. At the same time, they can be experienced as contradictory where organizational practices and the socio-cultural imperatives of individual responsibility, cost containment, and rationed services are concerned. Where 'house' tends to evoke a sense of permanent stability, 'home' is regarded as the ideal living environment and site of care for older people...
December 2016: Journal of Aging Studies
https://www.readbyqxmd.com/read/27590294/reducing-costs-while-enhancing-quality-of-care-in-ms
#17
Ilya Kister, John R Corboy
The rapid escalation in prices of disease-modifying therapies (DMTs) for multiple sclerosis (MS) over the past decade has resulted in a dramatic overall increase in the costs of MS-related care. In this article, we outline various approaches whereby neurologists can contribute to responsible cost containment while maintaining, and even enhancing, the quality of MS care. The premise of the article is that clinicians are uniquely positioned to introduce innovative management strategies that are both medically sound and cost-efficient...
October 11, 2016: Neurology
https://www.readbyqxmd.com/read/27550866/stimulus-driven-reorienting-impairs-executive-control-of-attention-evidence-for-a-common-bottleneck-in-anterior-insula
#18
Fynn-Mathis Trautwein, Tania Singer, Philipp Kanske
A classical model of human attention holds that independent neural networks realize stimulus-driven reorienting and executive control of attention. Questioning full independence, the two functions do, however, engage overlapping networks with activations in cingulo-opercular regions such as anterior insula (AI) and a reverse pattern of activation (stimulus-driven reorienting), and deactivation (executive control) in temporoparietal junction (TPJ). To test for independent versus shared neural mechanisms underlying stimulus-driven and executive control of attention, we used fMRI and a task that isolates individual from concurrent demands in both functions...
August 22, 2016: Cerebral Cortex
https://www.readbyqxmd.com/read/27544888/judged-effectiveness-of-threat-and-coping-appraisal-anti-speeding-messages
#19
Rachel L Cathcart, A Ian Glendon
PURPOSE: Using a young driver sample, this experimental study sought to identify which combinations of threat-appraisal (TA) and coping-appraisal (CA) messages derived from protection motivation theory (PMT) participants would judge as most effective for themselves, and for other drivers. METHOD: The criterion variable was reported intention to drive within a signed speed limit. All possible TA/CA combinations of 18 previously highly-rated anti-speeding messages were presented both simultaneously and sequentially...
November 2016: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27529090/women-s-preferences-for-contralateral-prophylactic-mastectomy-an-investigation-using-protection-motivation-theory
#20
Stephanie Tesson, Imogen Richards, David Porter, Kelly-Anne Phillips, Nicole Rankin, Toni Musiello, Michelle Marven, Phyllis Butow
OBJECTIVE: Most women diagnosed with unilateral breast cancer without BRCA1 or BRCA2 mutations are at low risk of contralateral breast cancer. Contralateral Prophylactic Mastectomy (CPM) decreases the relative risk of contralateral breast cancer, but may not increase life expectancy; yet international uptake is increasing. This study applied protection motivation theory (PMT) to determine factors associated with women's intentions to undergo CPM. METHODS: Three hundred eighty-eight women previously diagnosed with unilateral breast cancer and of negative or unknown BRCA1 or BRCA2 status were recruited from an advocacy group's research database...
May 2016: Patient Education and Counseling
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