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Contouring guideline

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https://www.readbyqxmd.com/read/29786462/multi-institutional-study-of-the-variability-in-target-delineation-for-six-targets-commonly-treated-with-radiosurgery
#1
Helena Sandström, Hidefumi Jokura, Caroline Chung, Iuliana Toma-Dasu
BACKGROUND: Although accurate delineation of the target is a key factor of success in radiosurgery there are no consensus guidelines for target contouring. AIM: The aim of the present study was therefore to quantify the variability in target delineation and discuss the potential clinical implications, for six targets regarded as common in stereotactic radiosurgery. MATERIAL AND METHODS: Twelve Gamma Knife centers participated in the study by contouring the targets and organs at risks and performing the treatment plans...
May 22, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29761663/a-prospective-pilot-study-on-early-toxicity-from-a-simultaneously-integrated-boost-technique-for-canine-sinonasal-tumours-using-image-guided-intensity-modulated-radiation-therapy
#2
A Soukup, V Meier, S Pot, K Voelter, C Rohrer Bley
In order to overcome the common local treatment failure of canine sinonasal tumours, integrated boost techniques were tried in the cobalt/orthovoltage era, but dismissed because of unacceptable early (acute) toxicity. Intriguingly, a recent calculation study of a simultaneously integrated boost (SIB) technique for sinonasal irradiation using intensity-modulated radiation therapy (IMRT) predicted theoretical feasibility. In this prospective pilot study we applied a commonly used protocol of 10 × 4.2 Gy to the planning target volume (PTV) with a 20%-SIB dose to the gross tumour volume (GTV)...
May 14, 2018: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29745269/biophysical-and-photobiological-basics-of-water-filtered-infrared-a-hyperthermia-of-superficial-tumors
#3
Peter Vaupel, Helmut Piazena, Werner Müller, Markus Notter
Thermography-controlled, water-filtered infrared-A (wIRA) is a novel, effective and approved heating technique listed in the ESHO quality assurance guidelines for superficial hyperthermia clinical trials (2017). In order to assess the special features and the potential of wIRA-hyperthermia (wIRA-HT), detailed and updated information about its physical and photobiological background is presented. wIRA allows for (a) application of high irradiances without skin pain and acute grade 2-4 skin toxicities, (b) prolonged, therapeutically relevant exposure times using high irradiances (150-200 mW/cm2 ) and (c) faster and deeper heat extension within tissues...
May 10, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29731160/contouring-of-prostate-tumors-on-multiparametric-mri-evaluation-of-clinical-delineations-in-a-multicenter-radiotherapy-trial
#4
Marcel A van Schie, Cuong V Dinh, Petra J van Houdt, Floris J Pos, Stijn W T J P Heijmink, Linda G W Kerkmeijer, Alexis N T J Kotte, Raymond Oyen, Karin Haustermans, Uulke A van der Heide
PURPOSE: To date no guidelines are available for contouring prostate cancer inside the gland, as visible on multiparametric (mp-) MRI. We assessed inter-institutional differences in interpretation of mp-MRI in the multicenter phase III FLAME trial. METHODS: We analyzed clinical delineations on mp-MRI and clinical characteristics from 260 patients across three institutes. We performed a logistic regression analysis to examine each institute's weighting of T2w, ADC and Ktrans intensity maps in the delineation of the cancer...
May 3, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29724416/acr-appropriateness-criteria-%C3%A2-breast-implant-evaluation
#5
Ana P Lourenco, Linda Moy, Paul Baron, Aarati D Didwania, Roberta M diFlorio, Samantha L Heller, Anna I Holbrook, Alana A Lewin, Tejas S Mehta, Bethany L Niell, Priscilla J Slanetz, Ashley R Stuckey, Daymen S Tuscano, Nina S Vincoff, Susan P Weinstein, Mary S Newell
Breast implant imaging varies depending on patient age, implant type, and symptoms. For asymptomatic patients (any age, any implant), imaging is not recommended. Rupture of saline implants is often clinically evident, as the saline is resorbed and there is a change in breast contour. With saline implants and equivocal clinical findings, ultrasound (US) is the examination of choice for patients less than 30 years of age, either mammography/digital breast tomosynthesis or US may be used for those 30 to 39 years of age, and mammography/digital breast tomosynthesis is used for those 40 years and older...
May 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29657889/pre-operative-versus-post-operative-radiosurgery-for-brain-metastasis-effects-on-treatment-volume-and-inter-observer-variability
#6
B A Vellayappan, J Doody, E Vandervoort, J Szanto, J Sinclair, J M Caudrelier, S Malone
Purpose/Objectives: Compared to post-operative whole brain radiotherapy, resection cavity radiosurgery reduces impact on neuro-cognitive function and improves quality-of-life. However, coverage of the operative tract, in addition to tumour bed, may lead to large treatment volumes and inter-observer variability. We hypothesized that pre-operative radiosurgery reduces target volume size and inter-observer variability compared to post-operative radiosurgery. Materials/Methods: We identified 10 consecutive patients, with solitary brain metastasis, treated with post-operative cavity radiosurgery...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29596574/efficacy-and-safety-of-autologous-fat-transfer-in-facial-reconstructive-surgery-a-systematic-review-and-meta-analysis
#7
Todor K Krastev, Jip Beugels, Juliette Hommes, Andrzej Piatkowski, Irene Mathijssen, Rene van der Hulst
Importance: The use of autologous fat transfer (AFT) or lipofilling for correcting contour deformities is seen as one of the major breakthroughs in reconstructive plastic surgery. Its applications in facial reconstructive surgery have been of particular interest owing to the prospect of achieving autologous reconstruction by a minimally invasive approach. However, its unpredictability and variable degree of resorption have limited its utility and much skepticism still exists regarding its efficacy...
March 29, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29594251/the-embrace-ii-study-the-outcome-and-prospect-of-two-decades-of-evolution-within-the-gec-estro-gyn-working-group-and-the-embrace-studies
#8
REVIEW
Richard Pötter, Kari Tanderup, Christian Kirisits, Astrid de Leeuw, Kathrin Kirchheiner, Remi Nout, Li Tee Tan, Christine Haie-Meder, Umesh Mahantshetty, Barbara Segedin, Peter Hoskin, Kjersti Bruheim, Bhavana Rai, Fleur Huang, Erik Van Limbergen, Max Schmid, Nicole Nesvacil, Alina Sturdza, Lars Fokdal, Nina Boje Kibsgaard Jensen, Dietmar Georg, Marianne Assenholt, Yvette Seppenwoolde, Christel Nomden, Israel Fortin, Supriya Chopra, Uulke van der Heide, Tamara Rumpold, Jacob Christian Lindegaard, Ina Jürgenliemk-Schulz
The publication of the GEC-ESTRO recommendations one decade ago was a significant step forward for reaching international consensus on adaptive target definition and dose reporting in image guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer. Since then, IGABT has been spreading, particularly in Europe, North America and Asia, and the guidelines have proved their broad acceptance and applicability in clinical practice. However, a unified approach to volume contouring and reporting does not imply a unified administration of treatment, and currently both external beam radiotherapy (EBRT) and IGABT are delivered using a large variety of techniques and prescription/fractionation schedules...
February 2018: Clinical and translational radiation oncology
https://www.readbyqxmd.com/read/29580932/postradiation-hypothyroidism-in-head-and-neck-cancers-a-department-of-veterans-affairs-single-institution-case-control-dosimetry-study
#9
Alexander J Lin, Juying Zhang, Jennie Cho-Lim, Warren Inouye, Steve P Lee
We performed a case-control study to characterize the dose-volume relationship and other variables leading to hypothyroidism after head and neck (H&N) cancer radiation therapy (RT) in a homogenous Veterans Affairs (VA) population. All records of patients receiving RT for various H&N cancers at a single VA medical center between 2007 and 2013 (n = 143) were screened for post-RT thyroid stimulating hormone (TSH) levels (n = 77). The thyroid gland was contoured on each slice of the planning computed tomography scan when available (hypothyroid: n = 18; euthyroid > 2 years: n = 16), and dose-volume histograms based on physical dose and biologically equivalent dose (BED) were compared systematically to find the significant dose-volume thresholds that distinguish the patients who developed clinical hypothyroidism...
March 23, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29545124/radiation-therapy-for-the-whole-breast-executive-summary-of-an-american-society-for-radiation-oncology-astro-evidence-based-guideline
#10
Benjamin D Smith, Jennifer R Bellon, Rachel Blitzblau, Gary Freedman, Bruce Haffty, Carol Hahn, Francine Halberg, Karen Hoffman, Kathleen Horst, Jean Moran, Caroline Patton, Jane Perlmutter, Laura Warren, Timothy Whelan, Jean L Wright, Reshma Jagsi
INTRODUCTION: The purpose of this guideline is to offer recommendations on fractionation for whole breast irradiation (WBI) with or without a tumor bed boost and guidance on treatment planning and delivery. METHODS AND MATERIALS: The American Society for Radiation Oncology (ASTRO) convened a task force to address 5 key questions focused on dose-fractionation for WBI, indications and dose-fractionation for tumor bed boost, and treatment planning techniques for WBI and tumor bed boost...
May 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29523410/an-atlas-to-aid-delineation-of-para-aortic-lymph-node-region-in-cervical-cancer-design-and-validation-of-contouring-guidelines
#11
Lorna G Keenan, Kathy Rock, Aini Azmi, Osama Salib, Charles Gillham, Orla McArdle
INTRODUCTION: Previous studies have investigated the anatomical distribution of para-aortic lymph nodes (PAN) in patients with cervical cancer. However, an atlas for accurate clinical target volume (CTV) delineation has yet to be defined. The purpose of this study was to design and verify a computerized tomography (CT) atlas to provide guidance for contouring the PAN CTV in patients with cervical cancer. MATERIALS AND METHODS: This prospective study included 21 cervical cancer patients (design cohort) with 39 pathological PAN identified on (18)F-FDG PET-CT...
March 6, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29503095/plastic-surgery-in-bariatric-patients-a-nationwide-study-of-17-000-patients-on-the-national-administrative-database
#12
Andrea Lazzati, Sandrine Katsahian, David Maladry, Emma Gerard, Sonia Gaucher
BACKGROUND: Bariatric patients are often candidates for plastic surgery. However, the rate of postbariatric procedures is not known. OBJECTIVES: The aim of this study was to analyze the rate of plastic surgery, and factors related to surgery, in bariatric patients. SETTING: University hospital, France. METHODS: This was a cohort study based on administrative data. All adult patients who received bariatric surgery in France between 2007 and 2013 were included to estimate the rate of plastic surgery and related predictive factors...
January 12, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29496327/the-influence-of-limbal-and-scleral-shape-on-scleral-lens-design
#13
REVIEW
Daddi Fadel
PURPOSE: To summarize the research findings on the ocular surface profile, to provide a definition and a classification of the corneoscleral shape, and to offer guidelines in selecting scleral lens design. METHODS: The definition of rotational symmetry and rotational asymmetry was inquired and PubMed searches were conducted. RESULTS: The better understanding of the scleral contact lens comportment on the eye and the introduction of new diagnostic instruments to measure the anterior ocular surface have led to improve comprehension of corneoscleral contour formulating new scleral lens designs...
February 26, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29496279/estro-acrop-consensus-guideline-on-ct-and-mri-based-target-volume-delineation-for-primary-radiation-therapy-of-localized-prostate-cancer
#14
Carl Salembier, Geert Villeirs, Berardino De Bari, Peter Hoskin, Bradley R Pieters, Marco Van Vulpen, Vincent Khoo, Ann Henry, Alberto Bossi, Gert De Meerleer, Valérie Fonteyne
BACKGROUND AND PURPOSE: Delineation of clinical target volumes (CTVs) remains a weak link in radiation therapy (RT), and large inter-observer variation is seen. Guidelines for target and organs at risk delineation for prostate cancer in the primary setting are scarce. The aim was to develop a delineation guideline obtained by consensus between a broad European group of radiation oncologists. MATERIAL AND METHODS: An ESTRO contouring consensus panel consisting of leading radiation oncologists and one radiologist with known subspecialty expertise in prostate cancer was asked to delineate the prostate, seminal vesicles and rectum on co-registered CT and MRI scans...
April 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29487771/machine-specific-magnetic-resonance-imaging-quality-control-procedures-for-stereotactic-radiosurgery-treatment-planning
#15
Ali Fatemi, Somayeh Taghizadeh, Claus Chunli Yang, Madhava R Kanakamedala, Bart Morris, Srinivasan Vijayakumar
Purpose Magnetic resonance (MR) images are necessary for accurate contouring of intracranial targets, determination of gross target volume and evaluation of organs at risk during stereotactic radiosurgery (SRS) treatment planning procedures. Many centers use magnetic resonance imaging (MRI) simulators or regular diagnostic MRI machines for SRS treatment planning; while both types of machine require two stages of quality control (QC), both machine- and patient-specific, before use for SRS, no accepted guidelines for such QC currently exist...
December 18, 2017: Curēus
https://www.readbyqxmd.com/read/29485068/delineation-of-neck-clinical-target-volume-specific-to-nasopharyngeal-carcinoma-based-on-lymph-node-distribution-and-the-international-consensus-guidelines
#16
Li Lin, Yao Lu, Xiao-Ju Wang, Hui Chen, Sha Yu, Jiao Tian, Guan-Qun Zhou, Lu-Lu Zhang, Zhen-Yu Qi, Jiang Hu, Jun Ma, Ying Sun
PURPOSE: To establish the regional lymph node (LN) distribution probability map and draw the neck clinical target volume specific to nasopharyngeal carcinoma (NPC). METHODS AND MATERIALS: One thousand patients with pathologically proven NPC were enrolled from January 2010 to December 2011. The center point of the LNs with a minimal axial diameter of ≥4 mm was marked on a single treatment planning computed tomography scan. The neck LN levels I to X using the 2013 updated international consensus guidelines were also contoured...
March 15, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29484714/implant-placement-in-the-esthetic-area-criteria-for-positioning-single-and-multiple-implants
#17
REVIEW
Tiziano Testori, Tommaso Weinstein, Fabio Scutellà, Hom-Lay Wang, Giovanni Zucchelli
Patient expectations from implant treatment have changed over the years and esthetics plays an important role in defining what is now called success of rehabilitation. Of the many factors that influence the outcome of the rehabilitation, the two main ones are the bone and soft-tissue deficiencies at the intended implant site. Many surgical approaches are described in terms of timing of implant placement and management of regenerative procedures. The aim of this article is to discuss the different implant placement alternatives in the esthetic area, in particular: (i) the timing of implant placement/regenerative procedures/skeletal growth/altered passive eruption; (ii) the correct three-dimensional position of the fixture between the cuspids and in the premolar area; (iii) multiple missing teeth in the esthetic area with single tooth/pontic or cantilevered options/prosthetic compensation; (iv) placement of implants into infected sites; and (v) the influence of abutment and crown morphology on implant position...
June 2018: Periodontology 2000
https://www.readbyqxmd.com/read/29395757/standardized-model-of-porcine-resuscitation-using-a-custom-made-resuscitation-board-results-in-optimal-hemodynamic-management
#18
Jakob Wollborn, Eva Ruetten, Bjoern Schlueter, Joerg Haberstroh, Ulrich Goebel, Martin A Schick
AIM: Standardized modeling of cardiac arrest and cardiopulmonary resuscitation (CPR) is crucial to evaluate new treatment options. Experimental porcine models are ideal, closely mimicking human-like physiology. However, anteroposterior chest diameter differs significantly, being larger in pigs and thus poses a challenge to achieve adequate perfusion pressures and consequently hemodynamics during CPR, which are commonly achieved during human resuscitation. The aim was to prove that standardized resuscitation is feasible and renders adequate hemodynamics and perfusion in pigs, using a specifically designed resuscitation board for a pneumatic chest compression device...
January 22, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29364284/guidelines-and-experience-using-imaging-biomarker-explorer-ibex-for-radiomics
#19
Rachel B Ger, Carlos E Cardenas, Brian M Anderson, Jinzhong Yang, Dennis S Mackin, Lifei Zhang, Laurence E Court
Imaging Biomarker Explorer (IBEX) is an open-source tool for medical imaging radiomics work. The purpose of this paper is to describe how to use IBEX's graphical user interface (GUI) and to demonstrate how IBEX calculated features have been used in clinical studies. IBEX allows for the import of DICOM images with DICOM radiation therapy structure files or Pinnacle files. Once the images are imported, IBEX has tools within the Data Selection GUI to manipulate the viewing of the images, measure voxel values and distances, and create and edit contours...
January 8, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29297232/dosimetric-quantification-of-the-incidental-irradiation-of-the-true-deep-ano-inguinal-lymphatic-drainage-of-anal-cancer-patients-not-described-in-conventional-contouring-guidelines
#20
Hendrik Dapper, Gregor Habl, Christoph Hirche, Stefan Münch, Markus Oechsner, Michael Mayinger, Christina Sauter, Stephanie E Combs, Daniel Habermehl
INTRODUCTION: The ano-inguinal lymphatic drainage (AILD) is located in the subcutaneous adipose tissue of the proximal medial thigh. Findings from fluorescence methods give us new information about anatomical conditions of the AILD. Current contouring guidelines do not advise the inclusion of the 'true' AILD into the clinical target volume (CTV). Aim of this work was the retrospective analysis of the incidental dose to the AILD in an anal cancer (AC) patient cohort who underwent definitive chemoradiation (CRT) therapy with Volumetric Arc Therapy - Intensity Modulated Radiation Therapy (VMAT-IMRT)...
January 3, 2018: Acta Oncologica
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