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Spirometry and lung function

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https://www.readbyqxmd.com/read/27907454/menopause-is-associated-with-accelerated-lung-function-decline
#1
Kai Triebner, Bobette Matulonga, Ane Johannessen, Sandra Suske, Bryndís Benediktsdóttir, Pascal Demoly, Shyamali C Dharmage, Karl A Franklin, Judith Garcia Aymerich, José Antonio Gullón Blanco, Joachim Heinrich, Mathias Holm, Debbie Jarvis, Rain Jõgi, Eva Lindberg, Jesús Martínez Moratalla Rovira, Nerea Muniozguren Agirre, Isabelle Pin, Nicole Probst-Hensch, Luca Puggini, Chantal Raherison, José Luis Sánchez-Ramos, Vivi Schlünssen, Jordi Sunyer, Cecilie Svanes, Steinar Hustad, Bénédicte Leynaert, Francisco Gómez Real
RATIONALE: Menopause is associated with changes in sex hormones, which affect immunity, inflammation, and osteoporosis and may impair lung function. Lung function decline has not previously been investigated in relation to menopause. OBJECTIVES: To study whether lung function decline, assessed by forced vital capacity and forced expiratory volume in one second, is accelerated in women who undergo menopause. METHODS: The population-based longitudinal European Community Respiratory Health Survey provided serum samples, spirometry and questionnaire data about respiratory and reproductive health from three study waves (N=1438)...
December 1, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27895274/disease-severity-prediction-by-spirometry-in-adults-with-visceral-leishmaniasis-from-minas-gerais-brazil
#2
Isabel A Maia, Frank S Bezerra, André Luis Pereira de Albuquerque, Heitor F Andrade, Valdir S Amato
Visceral leishmaniasis (VL) is associated with interstitial pneumonitis according to histology and radiology reports. However, studies to address the functional impact on respiratory function in patients are lacking. We assessed pulmonary function using noninvasive spirometry in a cross-sectional study of hospitalized adult VL patients from Minas Gerais, Brazil, without unrelated lung conditions or acute infections. Lung conditions were graded as normal, restrictive, obstructive, or mixed patterns, according to Brazilian consensus standards for spirometry...
November 28, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27894507/do-simple-beside-lung-function-tests-predict-morbidity-after-rib-fractures
#3
Christopher A Butts, John J Brady, Sara Wilhelm, Laura Castor, Alicia Sherwood, Abby McCall, John Patch, Pamela Jones, Vicente Cortes, Adrian W Ong
BACKGROUND: We evaluated if incentive spirometry volume (ISV) and peak expiratory flow rate (PEFR) could predict acute respiratory failure (ARF) in patients with rib fractures. METHODS: Normotensive, co-operative patients were enrolled prospectively. ISV and PEFR were measured on admission, at 24 h and at 48 h by taking the best of three readings each time. The primary outcome, ARF, was defined as requiring invasive or noninvasive positive pressure ventilation...
November 19, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27890986/correlation-of-chest-computed-tomography-findings-with-dyspnea-and-lung-functions-in-post-tubercular-sequelae
#4
Ananya Panda, Ashu Seith Bhalla, Raju Sharma, Anant Mohan, Vishnu Sreenivas, Umasankar Kalaimannan, Ashish Dutt Upadhyay
AIMS: To study the correlation between dyspnea, radiological findings, and pulmonary function tests (PFTs) in patients with sequelae of pulmonary tuberculosis (TB). MATERIALS AND METHODS: Clinical history, chest computed tomography (CT), and PFT of patients with post-TB sequelae were recorded. Dyspnea was graded according to the Modified Medical Research Council (mMRC) scale. CT scans were analyzed for fibrosis, cavitation, bronchiectasis, consolidation, nodules, and aspergilloma...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27888986/relationship-between-birth-weight-maternal-smoking-during-pregnancy-and-childhood-and-adolescent-lung-function-a-path-analysis
#5
Pallavi Balte, Wilfried Karmaus, Graham Roberts, Ramesh Kurukulaaratchy, Frances Mitchell, Hasan Arshad
BACKGROUND: Low birth weight and gestational maternal smoking have been linked with reduced lung function in children in many cross sectional studies. However, these associations have not yet been assessed with repeated measurements of lung function. Our aim was to investigate the effects of birth weight, gestational age, and gestational maternal smoking on lung function in children at age 10 and 18 years. METHODS: In the Isle of Wight birth cohort spirometry was performed at age 10 and 18 years...
December 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27884144/assessment-of-serology-and-spirometry-and-the-combination-of-both-to-complement-microbiological-isolation-for-earlier-detection-of-pseudomonas-aeruginosa-infection-in-children-with-cystic-fibrosis
#6
Ana Kotnik Pirš, Uroš Krivec, Saša Simčič, Katja Seme
BACKGROUND: The aim of this study was to assess whether serology and spirometry and the combination of both can complement culture-based detection for earlier recognition of Pseudomonas aeruginosa infection in children with cystic fibrosis. METHODS: A 4 year longitudinal prospective study that included 67 Slovenian children with cystic fibrosis with a mean age of 10.5 years was conducted. Serology, spirometry and a scoring system combining serology and spirometry were assessed and compared...
November 25, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27882012/individualized-supervised-resistance-training-during-nebulization-in-adults-with-cystic-fibrosis
#7
Ina Shaw, Janine E Kinsey, Roxanne Richards, Brandon S Shaw
BACKGROUND & OBJECTIVE: Since dyspnea limits exercise adherence and intensity in cystic fibrosis (CF) patients, engaging in resistance training (RT), which causes less dyspnea than other exercise modalities, while using nebulizers could not only overcome this barrier, but also enhance long-term adaptations to treatment. The objective of this study was to examine the effects of RT during nebulization on spirometry, anthropometry, chest wall excursion, respiratory muscle strength and health-related quality of life (HRQOL)...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27865240/prediction-equations-for-spirometry-in-adults-in-western-india
#8
Unnati Desai, Jyotsna M Joshi, S K Chhabra, Mujeeb-Ur Rahman
BACKGROUND: Spirometry is an essential investigation in pulmonology. The predicted normal spirometry values depend on various physiological parameters. This study was conducted to collect updated information on pulmonary functions in normal adults from western India. MATERIAL AND METHODS: A prospective observational study was undertaken at a tertiary hospital in Mumbai enrolling healthy subjects, 18-75 years, with ethnic origin from western India. Spirometry measurements were carried out as per ATS/ERS-2005 guidelines using a non-heated Fleish Pneumotachograph spirometer...
July 2016: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/27859629/changes-in-ventilatory-capacity-and-pulmonary-gas-exchange-during-systemic-and-pulmonary-inflammation-in-humans
#9
Jacob P Hartmann, Mathis N Mottelson, Ronan M G Berg, Ronni R Plovsing
The exact mechanism linking the systemic inflammatory response associated with sepsis to changes in lung function remains to be determined. In a human experimental model of inflammation, we investigated how acute systemic and local pulmonary inflammation affects ventilatory capacity and pulmonary gas exchange. Fifteen volunteers received Escherichia coli lipopolysaccharide (LPS) intravenously or endobronchially on two different study days. Blood samples were obtained hourly (t = 0-8 h) and spirometry was performed at baseline and after 8 h...
November 16, 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27856493/genetic-and-environmental-effects-on-telomere-length-and-lung-function-a-twin-study
#10
Elina Sillanpää, Sarianna Sipilä, Timo Törmäkangas, Jaakko Kaprio, Taina Rantanen
BACKGROUND: The purpose of the study was to estimate the heritability of leukocyte telomere length (LTL) and lung function and to examine whether LTL and lung function share genetic or environmental effects in common. METHODS: 386 monozygotic and dizygotic Finnish twin sisters (age 68.4±3.4 years) were included. Relative LTL was determined from peripheral blood DNA by qPCR. Lung function measures of FEV1, FVC, FEV1/FVC, and PEF were derived from spirometry. Genetic modeling was performed with MPlus statistical software...
November 16, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27855687/diagnostic-accuracy-of-methacholine-challenge-tests-assessing-airway-hyperreactivity-in-asthmatic-patients-a-multifunctional-approach
#11
Richard Kraemer, Hans-Jürgen Smith, Thomas Sigrist, Gabi Giger, Roland Keller, Martin Frey
BACKGROUND: There are few studies comparing diagnostic accuracy of different lung function parameters evaluating dose-response characteristics of methacholine (MCH) challenge tests (MCT) as quantitative outcome of airway hyperreactivity (AHR) in asthmatic patients. The aim of this retrospectively analysis of our database (Clinic Barmelweid, Switzerland) was, to assess diagnostic accuracy of several lung function parameters quantitating AHR by dose-response characteristics. METHODS: Changes in effective specific airway conductance (sGeff) as estimate of the degree of bronchial obstruction were compared with concomitantly measured forced expiratory volume in 1 s (FEV1) and forced expiratory flows at 50% forced vital capacity (FEF50)...
November 17, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27853363/effects-of-long-term-bronchodilators-in-bronchiectasis-patients-with-airflow-limitation-based-on-bronchodilator-response-at-baseline
#12
Ho Jung Jeong, Hyun Lee, Keumhee C Carriere, Jung Hoon Kim, Jin-Hyung Han, Beomsu Shin, Byeong-Ho Jeong, Won-Jung Koh, O Jung Kwon, Hye Yun Park
PURPOSE: The association between positive bronchodilator response (BDR) at baseline and the effect of long-term bronchodilator therapy has not been well elucidated in patients with bronchiectasis. The aims of our study were to explore the association between positive BDR at baseline and lung-function improvement following long-term (3-12 months) bronchodilator therapy in bronchiectasis patients with airflow limitation. MATERIALS AND METHODS: The medical records of 166 patients with clinically stable bronchiectasis who underwent baseline pre- and postbronchodilator spirometry and repeated spirometry after 3-12 months of bronchodilator therapy were retrospectively reviewed...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27853036/idiopathic-pulmonary-fibrosis-misdiagnosed-as-sputum-negative-pulmonary-tuberculosis
#13
Muhammad Danasabe Isah, Aminu Abbas, Abdullahi A Abba, Mohammed Umar
Idiopathic pulmonary fibrosis (IPF), also known as cryptogenic fibrosing alveolitis, is one of a spectrum of idiopathic interstitial pneumonia. IPF is an increasingly common condition which poses many diagnostic and therapeutic challenges leading to misdiagnosis and mismanagement. We presented a 55-year-old male textile trader who was initially managed as sputum-negative pulmonary tuberculosis before histology report. He presented to our clinic with Breathlessness and cough of 3 years and 2.5 years, respectively...
October 2016: Annals of African Medicine
https://www.readbyqxmd.com/read/27849230/primary-hypogammaglobulinemia-the-impact-of-early-diagnosis-in-lung-complications
#14
Mayra de Barros Dorna, Cristiane de Jesus Nunes Dos Santos, Ana Paula Beltran Moschione Castro, Luiz Antônio Nunes de Oliveira, Lisa Suzuki, Andrea Langone Ferme, Magda Maria Sales Carneiro-Sampaio, Antonio Carlos Pastorino
Objective: To describe clinical features, tomographic findings and pulmonary function in pediatric patients with primary hypogammaglobulinemia (PH). Method: A retrospective cohort study of children with PH who received intravenous immunoglobulin (IVIG) and prophylactic antibiotics between 2005 and 2010. Epidemiological and clinical features, computed tomography (CT) findings, and spirometric data were compared, assuming a 5% significance level. Results: We evaluated 30 patients with PH...
September 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27849141/eight-year-follow-up-of-airway-hyperresponsiveness-in-patients-with-primary-sj%C3%A3-gren-s-syndrome
#15
Dora Ludviksdottir, Sigridur Th Valtysdottir, Hans Hedenström, Roger Hällgren, Björn Gudbjörnsson
OBJECTIVE: To evaluate in a longitudinal study the influence of airway hyperresponsiveness (AHR) on lung function in patients with primary Sjögren's syndrome (pSS). METHODS: Lung function was studied over an eight-year period in 15 patients who fulfilled the Copenhagen criteria for primary Sjögren's syndrome and who were covered in our earlier published study on AHR in patients with Sjögren's syndrome. Standard spirometry and measurements of lung volumes, diffusing capacity (DLCO), and AHR to methacholine were performed...
November 16, 2016: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/27846350/-pulmonary-function-assessment-in-juvenile-idiopathic-scoliosis-managed-with-posterior-instrumentation-with-a-sublaminar-hook-system
#16
I González-Delgadillo, E Zamudio-Carrera, L V Díaz de León-Morales, A Rodríguez-Pérez
INTRODUCTION: Scoliosis is a spine deformity diagnosed using Cobbs method when the AP X-ray view shows an angulation greater than 10º. Scoliosis exceeding 50º results in restrictive pulmonary alterations. Surgical management improves the angulation and the pulmonary restrictive process. The pre- and post-operative pulmonary function values were compared using spirometry. MATERIAL AND METHODS: 27 patients of both genders, ages 11-15 years, underwent corrective surgery using posterior instrumentation with sublaminar hooks, rods and posterolateral arthrodesis...
March 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27834336/evaluation-of-symptoms-spirometry-in-children-treated-for-asthma
#17
Shobi Anandi, Milind S Tullu, Keya Lahiri
BACKGROUND & OBJECTIVES: Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with treatment in children with newly diagnosed asthma and to compare the changes in the symptom score and spirometric measurements...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27833966/analysis-of-bronchoalveolar-lavage-fluid-in-a-first-romanian-pulmonary-alveolar-proteinosis-cohort
#18
Oana Claudia Deleanu, Ana Maria Zaharie, Aneta Şerbescu, Floarea Mimi NiŢu, Florin Dumitru MihălŢan, Oana Cristina Arghir
The features of bronchoalveolar lavage fluid (BALF) components and the severity of pulmonary alveolar proteinosis (PAP) were analyzed in the first Romanian cohort of patients admitted to "Marius Nasta" Institute of Pneumophtisiology, Bucharest, Romania. A six-year follow-up study based on bronchoalveolar lavage (BAL) data was performed between January 2007 to December 2012. Study cohort consisted in 20 inpatients diagnosed with PAP, based on BALF cytological findings and÷or on histopathological findings. Demographic, medical history, tobacco use, clinical and radiological features, disease progression with or without whole lung lavage (WLL) therapy were collected...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27832236/evaluation-of-pulmonary-function-and-respiratory-symptoms-in-pyrochlore-mine-workers
#19
Ritta de Cássia Canedo Oliveira Borges, José Cerqueira Barros, Fabrício Borges Oliveira, Marisa Andrade Brunherotti, Paulo Roberto Veiga Quemelo
Objective: To identify respiratory symptoms and evaluate lung function in mine workers. Methods: This was a cross-sectional observational study involving production sector workers of a pyrochlore mining company. The subjects completed the British Medical Research Council questionnaire, which is designed to evaluate respiratory symptoms, occupational exposure factors, and smoking status. In addition, they underwent pulmonary function tests with a portable spirometer...
July 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27832235/influence-of-heart-failure-on-resting-lung-volumes-in-patients-with-copd
#20
Aline Soares de Souza, Priscila Abreu Sperandio, Adriana Mazzuco, Maria Clara Alencar, Flávio Ferlin Arbex, Mayron Faria de Oliveira, Denis Eunan O'Donnell, José Alberto Neder
Objective: To evaluate the influence of chronic heart failure (CHF) on resting lung volumes in patients with COPD, i.e., inspiratory fraction-inspiratory capacity (IC)/TLC-and relative inspiratory reserve-[1 - (end-inspiratory lung volume/TLC)]. Methods: This was a prospective study involving 56 patients with COPD-24 (23 males/1 female) with COPD+CHF and 32 (28 males/4 females) with COPD only-who, after careful clinical stabilization, underwent spirometry (with forced and slow maneuvers) and whole-body plethysmography...
July 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
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