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Spirometry and lung function

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https://www.readbyqxmd.com/read/28630566/the-global-lung-function-initiative-2012-equations-are-as-well-suited-as-local-population-derived-equations-to-a-sample-of-healthy-professional-firefighters
#1
Flynn Slattery, Tjard Schermer, Adrian Esterman, Kylie Johnston, Alan Crockett
BACKGROUND AND OBJECTIVE: We aimed to assess the validity of using the Global Lung Function Initiative's (GLI) 2012 equations to interpret lung function data in a healthy workforce of South Australian Metropolitan Fire Service (SAMFS) personnel. METHODS: Spirometry data from 212 healthy, nonsmoking SAMFS firefighters were collected and predicted normal values were calculated using both the GLI and local population derived (Gore) equations for forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and FEV1/FVC...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28629419/effect-of-beta-blockers-on-exacerbation-rate-and-lung-function-in-chronic-obstructive-pulmonary-disease-copd
#2
Sean Duffy, Robert Marron, Helen Voelker, Richard Albert, John Connett, William Bailey, Richard Casaburi, J Allen Cooper, Jeffrey L Curtis, Mark Dransfield, MeiLan K Han, Barry Make, Nathaniel Marchetti, Fernando Martinez, Stephen Lazarus, Dennis Niewoehner, Paul D Scanlon, Frank Sciurba, Steven Scharf, Robert M Reed, George Washko, Prescott Woodruff, Charlene McEvoy, Shawn Aaron, Don Sin, Gerard J Criner
BACKGROUND: Beta-blockers are commonly prescribed for patients with cardiovascular disease. Providers have been wary of treating chronic obstructive pulmonary disease (COPD) patients with beta-blockers due to concern for bronchospasm, but retrospective studies have shown that cardio-selective beta-blockers are safe in COPD and possibly beneficial. However, these benefits may reflect symptom improvements due to the cardiac effects of the medication. The purpose of this study is to evaluate associations between beta-blocker use and both exacerbation rates and longitudinal measures of lung function in two well-characterized COPD cohorts...
June 19, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28629359/forced-expiration-measurements-in-mouse-models-of-obstructive-and-restrictive-lung-diseases
#3
Fien C Devos, André Maaske, Annette Robichaud, Lore Pollaris, Sven Seys, Carolina Aznar Lopez, Erik Verbeken, Matthias Tenbusch, Rik Lories, Benoit Nemery, Peter Hm Hoet, Jeroen Aj Vanoirbeek
BACKGROUND: Pulmonary function measurements are important when studying respiratory disease models. Both resistance and compliance have been used to assess lung function in mice. Yet, it is not always clear how these parameters relate to forced expiration (FE)-related parameters, most commonly used in humans. We aimed to characterize FE measurements in four well-established mouse models of lung diseases. METHOD: Detailed respiratory mechanics and FE measurements were assessed concurrently in Balb/c mice, using the forced oscillation and negative pressure-driven forced expiration techniques, respectively...
June 19, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28619955/pulmonary-artery-to-aorta-ratio-and-risk-of-all-cause-mortality-in-the-general-population-the-rotterdam-study
#4
Natalie Terzikhan, Daniel Bos, Lies Lahousse, Lennard Wolff, Katia M C Verhamme, Maarten J G Leening, Janine F Felix, Henning Gall, Hossein A Ghofrani, Oscar H Franco, M Arfan Ikram, Bruno H Stricker, Aad van der Lugt, Guy Brusselle
A pulmonary artery to aorta ratio (PA:A) >1 is a proxy of pulmonary hypertension. It is not known whether this measure carries prognostic information in the general population and in individuals with chronic obstructive pulmonary disease (COPD).Between 2003 and 2006, 2197 participants from the population-based Rotterdam Study (mean±sd age 69.7±6.7 years; 51.3% female), underwent cardiac computed tomography (CT) scanning with PA:A quantification, defined as the ratio between the diameters of the pulmonary artery and the aorta...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28617349/investigation-of-acute-pulmonary-deficits-associated-with-biomass-fuel-cookstove-emissions-in-rural-bangladesh
#5
Danielle N Medgyesi, Heather A Holmes, Jeff E Angermann
The use of solid biomass fuels in cookstoves has been associated with chronic health impacts that disproportionately affect women worldwide. Solid fuel stoves that use wood, plant matter, and cow dung are commonly used for household cooking in rural Bangladesh. This study investigates the immediate effects of acute elevated cookstove emission exposures on pulmonary function. Pulmonary function was measured with spirometry before and during cooking to assess changes in respiratory function during exposure to cookstove emissions for 15 females ages 18-65...
June 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28613924/spirometry-reference-equations-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#6
Lisa LaVange, Sonia M Davis, John Hankinson, Paul Enright, Rebbecca Wilson, R Graham Barr, Thomas K Aldrich, Ravi Kalhan, Hector Lemus, Ai Ni, Lewis J Smith, Gregory A Talavera
RATIONALE: Accurate reference values for spirometry are important, as the results are used for diagnosing common chronic lung diseases such as asthma and chronic obstructive pulmonary disease, estimating physiological impairment, and predicting all-cause mortality. Reference equations have been established for Mexican Americans but not for other Hispanic/Latino backgrounds. OBJECTIVES: To develop spirometry reference equations for adult Hispanic/Latino background groups in the United States...
June 14, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28612960/physical-activity-and-asthma-control-level-in-children-and-adolescents
#7
Natasha Y Matsunaga, Marina S Oliveira, André M Morcillo, José D Ribeiro, Maria A G O Ribeiro, Adyléia A D C Toro
BACKGROUND AND OBJECTIVE: Physical activity is defined as any bodily movement produced by a muscle contraction with increased energy expenditure. The aim of this study was to assess the physical activity, asthma control level, spirometric measurements and quality of life in children and adolescents with asthma. METHODS: We included all children and adolescents aged 7-17 years who had a diagnosis of atopic asthma and who attended the Pediatric Pulmonology Outpatient Clinic of the State University of Campinas, Brazil...
June 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28611235/improvement-in-exercise-duration-lung-function-and-well-being-in-g551d-cystic-fibrosis-patients-a-double-blind-placebo-controlled-randomised-cross-over-study-with-ivacaftor
#8
Dominic T Keating, Deirdre Edgeworth, Matthew Ellis, Brenda Button, Elyssa Williams, Denise Clark, Audrey Tierney, Stephane Heritier, Anastase Kotsimbos, John Wilson
G551D , a mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, results in impaired chloride channel function in cystic fibrosis (CF) with multiple end-organ manifestations. The effect of ivacaftor, a CFTR-potentiator, on exercise capacity in cystic fibrosis (CF) is unknown. Twenty G551D-CF patients were recruited to a single-centre, double-blind, placebo-controlled, 28-day crossover study of ivacaftor. Variables measured included percentage change from baseline (%Δ) of VO2max (maximal oxygen consumption, primary outcome) during cardiopulmonary exercise testing (CPET), relevant other CPET physiological variables, lung function, BMI, sweat chloride, and disease specific health related quality of life (QOL) measures (CFQ-R and Alfred Wellness (AWEscore))...
June 13, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28609218/lung-function-measures-following-simulated-wildland-firefighter-exposures
#9
Matthew D Ferguson, Erin O Semmens, Emily Weiler, Joe Domitrovich, Mary French, Christopher Migliaccio, Charles Palmer, Charles Dumke, Tony Ward
Across the world, biomass smoke is a major source of air pollution and is linked with a variety of adverse health effects. This is particularly true in the western US where wood smoke from wildland forest fires are a significant source of PM2.5. Wildland firefighters are impacted as they experience elevated PM2.5 concentrations over extended periods of time, often occurring during physical exertion. Various epidemiological studies have investigated wood smoke impacts on human health, including occupational field exposures experienced by wildland firefighters...
June 13, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28608719/home-monitoring-in-cf-to-identify-and-treat-acute-pulmonary-exacerbations-eice-study-results
#10
Noah Lechtzin, Nicole Mayer-Hamblett, Natalie E West, Sarah Allgood, Ellen Wilhelm, Umer Khan, Moira L Aitken, Bonnie W Ramsey, Michael P Boyle, Peter J Mogayzel, Ronald L Gibson, David Orenstein, Carlos Milla, John P Clancy, Veena Antony, Christopher H Goss
RATIONALE: Individuals with cystic fibrosis (CF) suffer frequent acute pulmonary exacerbations, which lead to decreased lung function and reduced quality of life. OBJECTIVES: The goal of this study was to determine if an intervention directed toward early detection of pulmonary exacerbations using home spirometry and symptom monitoring would result in slower decline in lung function compared to controls. METHODS: A multicenter randomized trial at 14 CF centers in subjects ≥14 years...
June 13, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28603413/identifying-the-heterogeneity-of-copd-by-v-p-spect-a-new-tool-for-improving-the-diagnosis-of-parenchymal-defects-and-grading-the-severity-of-small-airways-disease
#11
M Bajc, Y Chen, J Wang, X Y Li, W M Shen, C Z Wang, H Huang, A Lindqvist, X Y He
INTRODUCTION: Airway obstruction and possible concomitant pulmonary diseases in COPD cannot be identified conventionally with any single diagnostic tool. We aimed to diagnose and grade COPD severity and identify pulmonary comorbidities associated with COPD with ventilation/perfusion single-photon emission computed tomography (V/P SPECT) using Technegas as the functional ventilation imaging agent. METHODS: 94 COPD patients (aged 43-86 years, Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages I-IV) were examined with V/P SPECT and spirometry...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28603348/functional-evaluation-of-breath-spirometry-and-body-plethysmography-comparison-in-people-with-cystic-fibrosis
#12
Jorge Hugo Villafañe, Camilo Corbellini, Elena Balestri, Stefania Dall'Ara, Federica Bazzocchi, Lucia Bertozzi
[Purpose] The aim of the present study was to establish up-to-date data regarding the lung function of cystic fibrosis (CF) patients. [Subjects and Methods] Forty-eight patients of both genders, with a diagnosis of CF, were recruited. As a result our sample presented, according to the GOLD criteria, 23 patients with mild lung obstruction (FEV1%pred: 89.86), 16 patients with moderate lung obstruction (FEV1%pred: 56.1) and 9 patients with severe obstruction (FEV1%pred: 32.1). [Results] All patients presented normal total lung capacity followed by an important residual volume increase...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28601355/yogic-breathing-practices-improve-lung-functions-of-competitive-young-swimmers
#13
Chirag Sunil Hakked, Ragavendrasamy Balakrishnan, Manjunath Nandi Krishnamurthy
BACKGROUND: Resistive breathing practices are known to improve endurance and performance in competitive swimmers. However, the effect of Pranayama or Yogic Breathing Practices (YBP) in improving respiratory endurance and performance of competitive swimmers remains un-investigated. OBJECTIVES: To study effects of yogic breathing practices on lung functions of swimmers. MATERIAL AND METHODS: Twenty seven national and international competitive swimmers of the age range 13-20 years, with 8...
June 7, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28598732/pulmonary-function-tests-for-the-radiologist
#14
Hsiang-Jer Tseng, Travis S Henry, Srihari Veeraraghavan, Pardeep K Mittal, Brent P Little
Pulmonary function tests (PFTs) provide important quantitative information about lung function and can be used to elucidate pathologic conditions responsible for respiratory symptoms, assess the severity and course of disease, and evaluate the patient for suitability and timing for lung transplantation. They are typically used in tandem with chest imaging, along with other ancillary data, to arrive at a specific diagnosis. PFTs may provide the radiologist with clues to the diagnosis and grading of a wide variety of pulmonary diseases...
June 9, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28586522/is-sweat-chloride-predictive-of-severity-of-cystic-fibrosis-lung-disease-assessed-by-chest-computed-tomography
#15
Daan Caudri, David Zitter, Inez Bronsveld, Harm Tiddens
BACKGROUND: Cystic Fibrosis (CF) lung disease is characterized by a marked heterogeneity. Sweat chloride-level is a functional marker of the CF Transmembrane Regulator (CFTR) protein and could be an important predictor of later disease severity. METHODS: In this retrospective analysis children from the Rotterdam CF clinic with available sweat chloride level at diagnosis and at least one routine spirometry-controlled volumetric chest CT scan in follow-up were included...
June 6, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28583260/the-case-for-impulse-oscillometry-in-the-management-of-asthma-in-children-and-adults
#16
REVIEW
Stanley P Galant, Hirsh D Komarow, Hye-Won Shin, Salman Siddiqui, Brian J Lipworth
OBJECTIVE: To provide a clinical rationale for including impulse oscillometry (IOS) as a part of standard office-based asthma assessment. DATA SOURCES: PubMed and Google search, limited to English language and human disease, with the keywords IOS and asthma. STUDY SELECTIONS: Articles included in this review were based on the expert opinion and previous publications by the authors. RESULTS: In children, IOS was more useful than spirometry in identifying asthma and uncontrolled asthma and predicting loss of control and exacerbations...
June 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28571133/influence-of-central-obesity-assessed-by-conicity-index-on-lung-age-in-young-adults
#17
Usha Shenoy, Jagadamba
INTRODUCTION: Central obesity is an emerging public health problem in young adults which compromises lung mechanics. Conicity Index (CI) is a simple anthropometric measure to assess central adiposity. The concept of lung age relates to a person's current lung function at which his/her lung function would be considered abnormal in relation to the present actual age. AIM: To determine the effect of central obesity by CI on lung age in young adults. MATERIALS AND METHODS: A total of 319 young adults in the age group 18-25 years were recruited for this cross-sectional observational study...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28570100/serum-matrix-metalloproteinase-7-respiratory-symptoms-and-mortality-in-community-dwelling-adults-the-multi-ethnic-study-of-atherosclerosis
#18
Hilary F Armstrong, Anna J Podolanczuk, R Graham Barr, Elizabeth C Oelsner, Steven M Kawut, Eric A Hoffman, Russell Tracy, Naftali Kaminski, Robyn L McClelland, David J Lederer
RATIONALE: Matrix metalloproteinase-7 (MMP-7) has been implicated in ILD pathobiology and proposed as a diagnostic and prognostic biomarker of IPF. OBJECTIVES: To test associations between serum MMP-7 and lung function, respiratory symptoms, interstitial lung abnormalities (ILA), and all-cause mortality in community-dwelling adults sampled without regard to respiratory symptoms or disease. METHODS: We measured serum MMP-7 in 1,227 participants in the Multi Ethnic Study of Atherosclerosis at basline...
June 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28559469/physiological-requirements-to-perform-the-glittre-activities-of-daily-living-test-by-subjects-with-mild-to-severe-copd
#19
Gérson F Souza, Graciane L Moreira, Andréa Tufanin, Mariana R Gazzotti, Antonio A Castro, José R Jardim, Oliver A Nascimento
BACKGROUND: The Glittre activities of daily living (ADL) test is supposed to evaluate the functional capacity of COPD patients. The physiological requirements of the test and the time taken to perform it by COPD patients in different disease stages are not well known. The objective of this work was to compare the metabolic, ventilatory, and cardiac requirements and the time taken to carry out the Glittre ADL test by COPD subjects with mild, moderate, and severe disease. METHODS: Spirometry, Medical Research Council questionnaire, cardiopulmonary exercise test, and 2 Glittre ADL tests were evaluated in 62 COPD subjects...
May 30, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28554711/scimitar-syndrome-anaesthetic-management-for-pulmonary-resection-of-the-unaffected-lung
#20
B Fernández-Torres, A Fernández-López, M Congregado
Scimitar syndrome is a rare congenital anomaly characterized by anomalous drainage of the right pulmonary veins in the inferior vena cava, frequently associated with right lung and pulmonary artery hypoplasia, dextrocardia and abnormal systemic arterial supply to the lower lobe. Pulmonary resection surgery on healthy lung is exceptional, and there are no published records of it, as far as we know. A man with scimitar syndrome diagnosed with a lung nodule with malignant features in the contralateral lung. This situation implies huge anaesthetic complexity, mainly for intraoperative ventilation...
May 26, 2017: Revista Española de Anestesiología y Reanimación
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