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Spirometry and lung function

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https://www.readbyqxmd.com/read/28100545/chronic-effects-of-air-pollution-on-lung-function-after-lung-transplantation-in-the-systems-prediction-of-chronic-lung-allograft-dysfunction-sysclad-study
#1
Meriem Benmerad, Rémy Slama, Karine Botturi, Johanna Claustre, Antoine Roux, Edouard Sage, Martine Reynaud-Gaubert, Carine Gomez, Romain Kessler, Olivier Brugière, Jean-François Mornex, Sacha Mussot, Marcel Dahan, Véronique Boussaud, Isabelle Danner-Boucher, Claire Dromer, Christiane Knoop, Annick Auffray, Johanna Lepeule, Laure Malherbe, Frederik Meleux, Laurent Nicod, Antoine Magnan, Christophe Pison, Valérie Siroux
An irreversible loss in lung function limits the long-term success in lung transplantation. We evaluated the role of chronic exposure to ambient air pollution on lung function levels in lung transplant recipients (LTRs).The lung function of 520 LTRs from the Cohort in Lung Transplantation (COLT) study was measured every 6 months. The levels of air pollutants (nitrogen dioxide (NO2), particulate matter with an aerodynamic cut-off diameter of x µm (PMx) and ozone (O3)) at the patients' home address were averaged in the 12 months before each spirometry test...
January 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28094013/pulmonary-outcome-of-esophageal-atresia-patients-and-its-potential-causes-in-early-childhood
#2
René Dittrich, Philippe Stock, Karin Rothe, Petra Degenhardt
INTRODUCTION: The aim of this study was to illustrate the pulmonary long term outcome of patients with repaired esophageal atresia and to further examine causes and correlations that might have led to this outcome. METHODS: Twenty-seven of 62 possible patients (43%) aged 5-20years, with repaired esophageal atresia were recruited. Body plethysmography and spirometry were performed to evaluate lung function, and the Bruce protocol treadmill exercise test to assess physical fitness...
January 3, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28087053/six-minute-walk-test-results-predict-risk-of-hospitalization-for-youths-with-cystic-fibrosis-a-5-year-follow-up-study
#3
Márcio V F Donadio, João P Heinzmann-Filho, Fernanda M Vendrusculo, Patrícia X H Frasson, Paulo J C Marostica
OBJECTIVE: To evaluate the association of 6-minute walk test (6MWT) and other variables (anthropometry, chronic Pseudomonas aeroginosa colonization, pulmonary function, and respiratory muscle strength) with the risk of hospitalization for pulmonary exacerbation in children and adolescents with cystic fibrosis (CF). STUDY DESIGN: Cohort study that included patients with CF aged 6-18 years. All participants underwent spirometry, manovacuometry, and 6MWT during the 5-year follow-up...
January 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28077140/indacaterol-and-glycopyrronium-versus-indacaterol-on-body-plethysmography-measurements-in-copd-a-randomised-controlled-study
#4
Joerg Salomon, Daiana Stolz, Guido Domenighetti, Jean-Georges Frey, Alexander J Turk, Andrea Azzola, Thomas Sigrist, Jean-William Fitting, Ulrich Schmidt, Thomas Geiser, Corinne Wild, Konstantinos Kostikas, Andreas Clemens, Martin Brutsche
BACKGROUND: Dual bronchodilator therapy is recommended for symptomatic patients with chronic obstructive pulmonary disease (COPD). There are limited data on effects of a combination of two long-acting bronchodilators on lung function including body plethysmography. METHODS: This multicentre, randomised, double-blind, single-dose, cross-over, placebo-controlled study evaluated efficacy and safety of the free combination of indacaterol maleate (IND) and glycopyrronium bromide (GLY) versus IND alone on spirometric and body plethysmography parameters, including inspiratory capacity (IC), forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), total lung capacity (TLC) and airway resistance (Raw) in moderate-to-severe COPD patients...
January 11, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28076945/effect-of-body-mass-index-on-pulmonary-function-in-children
#5
G Liyanage, B D Jayamanne, M Aaqiff, D Sriwardhana
Introduction: The relationship between obesity or overweight and pulmonary functions has not been investigated in Sri Lankan children previously. Therefore, we aimed to study the effects of obesity/overweight on dynamic lung functions in healthy school children in Sri Lanka. Methods: HASH(0x575eb70) Results: Of 275 children 55 (20%) were ‘obese/ overweight’. BMI has no significant relationship to any of the pulmonary function parameters...
30, 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28061834/prevalence-of-airflow-obstruction-in-patients-with-stable-systolic-heart-failure
#6
Morten Dalsgaard, Louis Lind Plesner, Morten Schou, Erik Kjøller, Jørgen Vestbo, Kasper Iversen
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an important differential diagnosis in heart failure (HF). However, routine use of spirometry in outpatient HF clinics is not implemented. The aim of the present study was to determine the prevalence of both airflow obstruction and non obstructive lung function impairment in patients with HF and to examine the effect of optimal medical treatment for HF on lung function parameters. METHODS: Consecutive patients with HF (ejection fraction (EF) < 45%) and New York Heart Association (NYHA) functional class II-IV at 10 different outpatient heart failure clinics were examined with spirometry at their first visit and after optimal medical treatment for HF was achieved...
January 6, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28057838/temporal-evolution-of-thoracocentesis-induced-changes-in-spirometry-and-respiratory-muscle-pressures
#7
Stylianos A Michaelides, George D Bablekos, Antonis Analitis, George Ionas, Petros Bakakos, Konstantinos A Charalabopoulos
BACKGROUND: Several studies investigated the effects of thoracocentesis on aspects of respiratory function without generally ensuring absence of coexistent lung pathology or homogeneity in initial size of the effusion. METHODS: We studied 90 patients aged 61.6±15.9 years (mean±SD) separated into a group A with small-sized or medium-sized effusion (A=56 patients) and a group B with large and massive one (B=34 patients). There was no significant lung lesion or cardiovascular pathology...
January 5, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28055281/effects-of-bronchoscopy-on-lung-function-in-asthmatics
#8
Christina Bellinger, Eugene R Bleecker, Stephen P Peters, Rodolfo M Pascual, Jeffrey Krings, Regina V Smith, Annette Hasties, Wendy C Moore
BACKGROUND: To better understand changes in pulmonary physiology related to asthma severity following bronchoscopy, we performed scheduled pre- and post-procedure spirometry on all subjects undergoing bronchoscopy in our research program. METHODS: Control subjects and asthma subjects of all severity were recruited for bronchoscopy. On the day of bronchoscopy, subjects underwent spirometry when they arrived, after pre-bronchoscopy treatment with albuterol and then up to three sets within two hours following completion of the bronchoscopy...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28053971/gold-criteria-overestimate-airflow-limitation-in-one-third-of-cases-in-the-general-finnish-population
#9
Annette Kainu, Kirsi Timonen, Ari Lindqvist, Päivi Piirilä
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) diagnostic criteria for chronic obstructive pulmonary disease (COPD) use a fixed threshold of forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio (<0.70) in post-bronchodilation spirometry to indicate disease, which has been shown to underestimate and overestimate disease prevalence in younger and older adults, respectively, whilst criteria based on reference values have better accuracy. Differences in reference values have limited their use in international studies...
October 2016: ERJ Open Research
https://www.readbyqxmd.com/read/28053968/electromagnetic-inductance-plethysmography-is-well-suited-to-measure-tidal-breathing-in-infants
#10
Mariann H L Bentsen, Morten Eriksen, Merete S Olsen, Trond Markestad, Thomas Halvorsen
Reliable, accurate and noninvasive methods for measuring lung function in infants are desirable. Electromagnetic inductance plethysmography has been used to perform infant spirometry and VoluSense Pediatrics (VSP) (VoluSense, Bergen, Norway) represents an updated version of this technique. We aimed to examine its accuracy compared to a validated system measuring airflow via a facemask using an ultrasonic flowmeter. We tested 30 infants with postmenstrual ages between 36 to 43 weeks and weights from 2.3 to 4...
October 2016: ERJ Open Research
https://www.readbyqxmd.com/read/28052294/comparison-of-three-screening-questionnaires-for-chronic-obstructive-pulmonary-disease-in-the-primary-care
#11
Dionisios Spyratos, Anna-Bettina Haidich, Diamantis Chloros, Dionisia Michalopoulou, Lazaros Sichletidis
BACKGROUND: Even though the diagnosis of chronic obstructive pulmonary disease (COPD) is easy and based mainly on spirometry and symptoms, the prevalence of underdiagnosis is extremely high. The use of simple screening tools (e.g., questionnaires, hand-held spirometers) has been proved to be a simple method for case finding of COPD. Nevertheless the most appropriate target group of the general population has not been specified yet. OBJECTIVES: The aim of the present study was to compare 3 screening questionnaires among smokers aged >40 years in the primary care setting...
January 5, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28051194/respiratory-symptoms-and-lung-function-among-greek-cotton-industry-workers-a-cross-sectional-study
#12
Ioannis D Anyfantis, Georgios Rachiotis, Cristos Hadjichristodoulou, Konstantinos I Gourgoulianis
BACKGROUND: Workers in cotton industry are occupationally exposed to various dust-related hazards. The nature of these agents and the respective exposure levels depend on the cotton industry specific sector. These exposures could be associated with respiratory symptoms and changes in lung function parameters. OBJECTIVE: To evaluate associations between occupational exposure and respiratory function as well as reported symptoms in several groups of workers at different stages of the cotton industry in a vertical approach that covers all the major sectors-from cotton ginning to weaving and fabric production...
January 2017: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28046566/we-ab-202-08-feasibility-of-single-inhalation-single-energy-xenon-ct-for-high-resolution-imaging-of-regional-lung-ventilation-in-humans
#13
D Pinkham, M Negahdar, E Schueler, T Yamamoto, M Diehn, E Mittra, B Loo, P Maxim
PURPOSE: To demonstrate the efficacy of a novel functional lung imaging method that utilizes single-inhalation, single-energy xenon CT (Xe-CT) lung ventilation scans, and to compare it against the current clinical standard, ventilation single-photon emission CT (V-SPECT). METHODS: In an IRB-approved clinical study, 14 patients undergoing thoracic radiotherapy received two successive single inhalation, single energy (80keV) CT images of the entire lung using 100% oxygen and a 70%/30% xenon-oxygen mixture...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044005/biomechanical-ct-metrics-are-associated-with-patient-outcomes-in-copd
#14
Sandeep Bodduluri, Surya P Bhatt, Eric A Hoffman, John D Newell, Carlos H Martinez, Mark T Dransfield, Meilan K Han, Joseph M Reinhardt
BACKGROUND: Traditional metrics of lung disease such as those derived from spirometry and static single-volume CT images are used to explain respiratory morbidity in patients with COPD, but are insufficient. We hypothesised that the mean Jacobian determinant, a measure of local lung expansion and contraction with respiration, would contribute independently to clinically relevant functional outcomes. METHODS: We applied image registration techniques to paired inspiratory-expiratory CT scans and derived the Jacobian determinant of the deformation field between the two lung volumes to map local volume change with respiration...
January 2, 2017: Thorax
https://www.readbyqxmd.com/read/28032549/size-capacity-mismatch-in-the-lung-a-novel-predictor-for-complications-after-lung-cancer-surgery
#15
Junichi Murakami, Kazuhiro Ueda, Masataro Hayashi, Taiga Kobayashi, Yoshie Kunihiro, Kimikazu Hamano
BACKGROUND: The aim of the present study was to make a combined pulmonary functional and anatomical assessment using spirometry and computed tomography (CT) to clarify the best predictor for cardiopulmonary complications after thoracoscopic major lung resection for cancer. METHODS: We retrospectively reviewed our prospective database of 304 patients undergoing thoracoscopic major lung resection for cancer. The total lung volume (TLV) was measured preoperatively using deep-inspiratory CT by summing the voxels representing -600 to -1024 Hounsfield units...
August 19, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/28029468/-usefulness-of-the-fev1-fev6-ratio-to-detect-the-prevalence-of-lung-obstruction-in-hospitalised-patients-with-multiple-morbidities
#16
María Vanesa Lorenzo Hernández, Sergi Yun, Eva Acosta, Pere Almagro
BACKGROUND: The prevalence of lung obstruction increases with age and the presence of comorbidities. Although a complete spirometry is necessary to confirm the diagnosis, this may be impractical in elderly patients with cognitive impairment or functional dependence. Recently, the use of portable devices using the FEV1/FEV6 ratio have shown to be useful for assessing the presence of lung obstruction, with greater ease of use, but its usefulness has not been established in the elderly population with multiple morbidities...
October 28, 2016: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28005431/lung-development-and-aging
#17
Andrew Bush
The onset of chronic obstructive pulmonary disease (COPD) can arise either from failure to attain the normal spirometric plateau or from an accelerated decline in lung function. Despite reports from numerous big cohorts, no single adult life factor, including smoking, accounts for this accelerated decline. By contrast, five childhood risk factors (maternal and paternal asthma, maternal smoking, childhood asthma and respiratory infections) are strongly associated with an accelerated rate of lung function decline and COPD...
December 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28004642/linearity-of-electrical-impedance-tomography-during-maximum-effort-breathing-and-forced-expiration-maneuvers
#18
Chuong Ngo, Steffen Leonhardt, Tony Zhang, Markus Lüken, Berno Misgeld, Thomas Vollmer, Klaus Tenbrock, Sylvia Lehmann
Electrical impedance tomography (EIT) provides global and regional information about ventilation by means of relative changes in electrical impedance measured with electrodes placed around the thorax. In combination with lung function tests, e.g. spirometry and body plethysmography, regional information about lung ventilation can be achieved. Impedance changes strictly correlate with lung volume during tidal breathing and mechanical ventilation. Initial studies presumed a correlation also during forced expiration maneuvers...
January 2017: Physiological Measurement
https://www.readbyqxmd.com/read/27994453/drop-in-lung-function-during-asthma-and-copd-exacerbations-can-it-be-assessed-without-spirometry
#19
Hasse Melbye, Salwan Al-Ani, Mark Spigt
BACKGROUND: When assessing patients with exacerbation of asthma or COPD, it may be useful to know the drop in forced expiratory volume in 1 second (FEV1) compared with stable state, in particular when considering treatment with oral corticosteroids. The objective of the study was to identify indicators of drop in FEV1 during exacerbations. METHODS: In this prospective multicenter study from primary care, patients diagnosed with asthma or COPD were examined at stable state and during exacerbations the following year...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27982344/early-open-lung-ventilation-improves-clinical-outcomes-in-patients-with-left-cardiac-dysfunction-undergoing-off-pump-coronary-artery-bypass-a-randomized-controlled-trial
#20
Douglas W Bolzan, Walter José Gomes, Isadora S Rocco, Marcela Viceconte, Mara L S Nasrala, Hayanne O Pauletti, Rita Simone L Moreira, Nelson A Hossne, Ross Arena, Solange Guizilini
Objective: To compare pulmonary function, functional capacity and clinical outcomes amongst three groups of patients with left ventricular dysfunction following off-pump coronary artery bypass, namely: 1) conventional mechanical ventilation (CMV); 2) late open lung strategy (L-OLS); and 3) early open lung strategy (E-OLS). Methods: Sixty-one patients were randomized into 3 groups: 1) CMV (n=21); 2) L-OLS (n=20) initiated after intensive care unit arrival; and 3) E-OLS (n=20) initiated after intubation...
September 2016: Brazilian Journal of Cardiovascular Surgery
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