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Spirometry and lung function

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https://www.readbyqxmd.com/read/28432861/spirometry-and-volumetric-capnography-in-lung-function-assessment-of-obese-and-normal-weight-individuals-without-asthma
#1
Mariana S Ferreira, Roberto T Mendes, Fernando A L Marson, Mariana P Zambon, Maria A R G M Antonio, Ilma A Paschoal, Adyléia A D C Toro, Silvana D Severino, Maria A G O Ribeiro, José D Ribeiro
OBJECTIVE: To analyze and compare lung function of obese and healthy, normal-weight children and adolescents, without asthma, through spirometry and volumetric capnography. METHODS: Cross-sectional study including 77 subjects (38 obese) aged 5-17 years. All subjects underwent spirometry and volumetric capnography. The evaluations were repeated in obese subjects after the use of a bronchodilator. RESULTS: At the spirometry assessment, obese individuals, when compared with the control group, showed lower values of forced expiratory volume in the first second by forced vital capacity (FEV1/FVC) and expiratory flows at 75% and between 25 and 75% of the FVC (p<0...
April 19, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28432267/assessment-of-lung-function-in-a-large-cohort-of-patients-with-acromegaly
#2
Sylvere Störmann, Bodo Gutt, Josefine Roemmler-Zehrer, Martin Bidlingmaier, Rudolf Maria Huber, Jochen Schopohl, Matthias Angstwurm
OBJECTIVE: Acromegaly is associated with increased mortality due to respiratory disease. To date, lung function in patients with acromegaly has only been assessed in small studies, with contradicting results. We assessed lung function parameters in a large cohort of patients with acromegaly. DESIGN: Lung function of acromegaly patients was prospectively assessed using spirometry, blood gas analysis and body plethysmography. Biochemical indicators of acromegaly were assessed through measurement of growth hormone and IGF-I levels...
April 21, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28431499/asthma-copd-overlap-syndrome-acos-in-primary-care-of-four-latin-america-countries-the-puma-study
#3
Maria Montes de Oca, Maria Victorina Lopez Varela, Maria E Laucho-Contreras, Alejandro Casas, Eduardo Schiavi, Juan Carlos Mora
BACKGROUND: Asthma-COPD overlap syndrome (ACOS) prevalence varies depending on the studied population and definition criteria. The prevalence and clinical characteristics of ACOS in an at-risk COPD primary care population from Latin America was assessed. METHODS: Patients ≥40 years, current/ex-smokers and/or exposed to biomass, attending routine primary care visits completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) < 0...
April 21, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28430622/serious-adverse-events-of-cell-therapy-for-respiratory-diseases-a-systematic-review-and-meta-analysis
#4
REVIEW
Runzhen Zhao, Zhenlei Su, Jing Wu, Hong-Long Ji
BACKGROUND: Cell therapy holds the most promising for acute and chronic deleterious respiratory diseases. However, the safety and tolerance for lung disorders are controversy. METHODS: We undertook a systematic review and meta-analyses of all 23 clinical studies of cell therapy. The outcomes were odds ratio (OR), risk difference (RD), Peto OR, relative risk, and mean difference of serious adverse events. RESULTS: 342 systemic infusions and 57 bronchial instillations (204 recipients) of cells were analyzed for acute respiratory distress syndrome (ARDS), bronchopulmonary dysplasia, pulmonary arterial hypertension, silicosis, sarcoidosis, extensively drug-resistant tuberculosis, chronic obstructive pulmonary diseases (COPD), and idiopathic pulmonary fibrosis...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28425826/lung-function-and-prevalence-of-respiratory-symptoms-in-norwegian-crab-processing-workers
#5
Marte R Thomassen, Lisbeth Aasmoe, Berit E Bang, Tonje Braaten
BACKGROUND: Seafood processing workers have an increased risk of developing occupational asthma. This has not been studied among Norwegian crab processing workers, nor has the respiratory health of exposed workers been compared to a control group. OBJECTIVES: Assessing the impact of working in the crab processing industry on workers' respiratory health. DESIGN: A cross-sectional study of the respiratory health in two types of crab processing workers compared to a control group...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28418337/a-simple-measure-to-assess-hyperinflation-and-air-trapping-1-forced-expiratory-volume-in-three-second-forced-vital-capacity
#6
Sermin Börekçi, Tunçalp Demir, Aslı Görek Dilektaşlı, Melahat Uygun, Nurhayat Yıldırım
BACKGROUND: Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC) may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. AIMS: To investigate the associations of 1-FEV3/FVC with the spirometric measures and lung volumes that assess small airways dysfunction and reflects hyperinflation and air trapping. STUDY DESIGN: Retrospective cross-sectional study...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28416951/spirometry-and-bronchodilator-test
#7
REVIEW
Yun Su Sim, Ji-Hyun Lee, Won-Yeon Lee, Dong In Suh, Yeon-Mok Oh, Jong-Seo Yoon, Jin Hwa Lee, Jae Hwa Cho, Cheol Seok Kwon, Jung Hyun Chang
Spirometry is a physiological test for assessing the functional aspect of the lungs using an objective indicator to measure the maximum amount of air that a patient can inhale and exhale. Acceptable spirometry testing needs to be conducted three times by an acceptable and reproducible method for determining forced vital capacity (FVC). Until the results of three tests meet the criteria of reproducibility, the test should be repeated up to eight times. Interpretation of spirometry should be clear, concise, and informative...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28415034/validation-of-a-new-mortality-risk-prediction-model-for-people-65-years-and-older-in-northwest-russia-the-crystal-risk-score
#8
Anna Turusheva, Elena Frolova, Vaes Bert, Eralda Hegendoerfer, Jean-Marie Degryse
BACKGROUND: Prediction models help to make decisions about further management in clinical practice. This study aims to develop a mortality risk score based on previously identified risk predictors and to perform internal and external validations. METHODS: In a population-based prospective cohort study of 611 community-dwelling individuals aged 65+ in St. Petersburg (Russia), all-cause mortality risks over 2.5 years follow-up were determined based on the results obtained from anthropometry, medical history, physical performance tests, spirometry and laboratory tests...
March 29, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28411113/restrictive-spirometry-pattern-is-associated-with-increased-arterial-stiffness-in-men-and-women
#9
I-Hsuan Wu, Zih-Jie Sun, Feng-Hwa Lu, Yi-Ching Yang, Chieh-Ying Chou, Chih-Jen Chang, Jin-Shang Wu
BACKGROUND: There is growing evidence that pulmonary function impairment has been found to be related to cardiovascular events and death. Some studies showed that the level of forced vital capacity (FVC) was negatively related to arterial stiffness, but most studies were confined to males and none of them examined the association of the presence of restrictive spirometry pattern with arterial stiffness. Therefore, this study aimed to investigate the association of restrictive spirometry pattern with arterial stiffness by gender...
April 11, 2017: Chest
https://www.readbyqxmd.com/read/28409283/body-composition-and-lung-function-in-children-with-cystic-fibrosis-and-meconium-ileus
#10
Artemis Doulgeraki, Argyri Petrocheilou, Glykeria Petrocheilou, George Chrousos, Stavros-Eleftherios Doudounakis, Athanasios G Kaditis
The aim of this study was to explore whether history of meconium ileus (MI) at birth in children and adolescents with cystic fibrosis (CF) adversely affects body composition and lung function in later life. Data of children and adolescents with CF who underwent spirometry and DXA as part of their routine care were analyzed. Associations between MI (explanatory variable) and areal bone mineral density (total body less head-TBLH aBMD), lean tissue mass (LTM), and fat mass (FM) (outcomes) were assessed using general linear models...
April 13, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28409004/effect-of-%C3%AE-blockade-on-lung-function-exercise-performance-and-dynamic-hyperinflation-in-people-with-arterial-vascular-disease-with-and-without-copd
#11
Angela Key, Matthew Parry, Malcolm A West, Rebecca Asher, Sandy Jack, Nick Duffy, Francesco Torella, Paul P Walker
INTRODUCTION: β Blockers are important treatment for ischaemic heart disease and heart failure; however, there has long been concern about their use in people with chronic obstructive pulmonary disease (COPD) due to fear of symptomatic worsening of breathlessness. Despite growing evidence of safety and efficacy, they remain underused. We examined the effect of β-blockade on lung function, exercise performance and dynamic hyperinflation in a group of vascular surgical patients, a high proportion of who were expected to have COPD...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28408655/military-small-arms-fire-in-association-with-acute-decrements-in-lung-function
#12
Anne Katrine Borander, Øyvind Albert Voie, Kjetil Longva, Tor Erik Danielsen, Svein Grahnstedt, Leiv Sandvik, Johny Kongerud, Liv Ingunn Bjoner Sikkeland
OBJECTIVE: After introduction of unleaded ammunition, Norwegian Armed Forces received reports of acute respiratory symptoms in soldiers after exposure to fumes from firing the standard weapon, HK416. The aim of the present study was to examine lung function before and after exposure to fumes from HK416 in a double-blinded standardised study design using three different types of ammunition. METHODS: Fifty-four healthy, non-smoking male volunteers (19-62 years) fired the weapons for 60 min with either leaded, unleaded or 'modified' unleaded ammunition...
April 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28404791/the-effect-of-organic-dust-exposure-on-long-term-change-in-lung-function-a-systematic-review-and-meta-analysis
#13
REVIEW
Anneli Cs Bolund, Martin R Miller, Torben Sigsgaard, Vivi Schlünssen
Lung function is a predictor of morbidity and mortality, and the chronic nature of lung function decline allows for preventive initiatives. Proinflammatory constituents of organic dust are considered a possible cause of compromised respiratory health. The aim of this systematic review was to reveal the impact of organic dust exposure on long-term change in lung function. The literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria...
April 12, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28403885/lung-structure-and-function-similarities-between-primary-ciliary-dyskinesia-and-mild-cystic-fibrosis-a-pilot-study
#14
Marco Maglione, Silvia Montella, Carmine Mollica, Vincenzo Carnovale, Paola Iacotucci, Fabiola De Gregorio, Antonella Tosco, Mariarosaria Cervasio, Valeria Raia, Francesca Santamaria
BACKGROUND: Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are increasingly compared. There are no chest magnetic resonance imaging (MRI) comparative studies of PCD and CF. We assessed clinical, functional, microbiological and MRI findings in PCD and mild CF patients in order to evaluate different expression of lung disease. METHODS: Twenty PCD (15.1 years) and 20 CF subjects with mild respiratory impairment (16 years, 70% with pancreatic insufficiency) underwent MRI, spirometry, and sputum cultures when clinically stable...
April 12, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28403098/the-effects-of-body-mass-index-on-spirometry-tests-among-adults-in-xi-an-china
#15
Shengyu Wang, Xiuzhen Sun, Te-Chun Hsia, Xiaobo Lin, Manxiang Li
Obese people have higher risk of respiratory symptoms. The relationship between obesity and lung function varies with age, race, and geographical region. The objective of this study is to examine the effects of body mass index on spirometric tests among adults in Xi'an city.This is a cross-sectional study. Pulmonary function testing was conducted on participants recruited from Xi'an, China between July and August 2012. Force expiratory volume in first second (FEV1), force vital capacity (FVC), FEV1/FVC, peak expiratory flow (PEF), and forced expiratory flow at 25-75% (FEF25-75) were measured by portable Spirometer...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28399675/evaluating-the-appropriateness-of-hospital-doctors-requests-for-pulmonary-function-tests-beyond-basic-spirometry-results-from-a-prospective-observational-study
#16
Krishna Bajee Sriram, Zoe Fountain, Jessica Hockenhull, Debbie Zagami
OBJECTIVES: Hospitalists request 'complete' pulmonary function tests (PFTs), typically comprising of spirometry, diffusion capacity of the lung for carbon monoxide (DLCO) and absolute lung volumes (ALVs), the results of which assist in the management of patients with respiratory disorders. Recently, concerns have been raised about over-requesting of 'complete' PFTs, but there is a paucity of information on the proportion of requests that can be considered clinically inappropriate. This study prospectively evaluated the 'complete' PFTs requested in a hospital service and assessed the impact of medical review of the requests...
April 19, 2017: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/28397992/mucoactive-agents-for-chronic-non-cystic-fibrosis-lung-disease-a-systematic-review-and-meta-analysis
#17
REVIEW
Benjamin J Tarrant, Caitlin Le Maitre, Lorena Romero, Ranjana Steward, Brenda M Button, Bruce R Thompson, Anne E Holland
Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. The effect of mannitol, recombinant human deoxyribonuclease/dornase alfa (rhDNase) and hypertonic saline (HS) or normal saline (NS) are not well described in chronic lung conditions other than cystic fibrosis (CF). The aim of this review was to determine the benefit and safety of inhaled mucoactive agents outside of CF. We searched Medline, Embase, CINAHL and CENTRAL for randomized controlled trials investigating the effects of mucoactive agents on lung function, adverse events (AEs), health-related quality of life (HRQOL), hospitalization, length of stay, exacerbations, sputum clearance and inflammation...
April 11, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28391173/the-impact-of-ambient-air-pollution-on-the-human-blood-metabolome
#18
J J Vlaanderen, N A Janssen, G Hoek, P Keski-Rahkonen, D K Barupal, F R Cassee, I Gosens, M Strak, M Steenhof, Q Lan, B Brunekreef, A Scalbert, R C H Vermeulen
BACKGROUND: Biological perturbations caused by air pollution might be reflected in the compounds present in blood originating from air pollutants and endogenous metabolites influenced by air pollution (defined here as part of the blood metabolome). We aimed to assess the perturbation of the blood metabolome in response to short term exposure to air pollution. METHODS: We exposed 31 healthy volunteers to ambient air pollution for 5h. We measured exposure to particulate matter, particle number concentrations, absorbance, elemental/organic carbon, trace metals, secondary inorganic components, endotoxin content, gaseous pollutants, and particulate matter oxidative potential...
April 5, 2017: Environmental Research
https://www.readbyqxmd.com/read/28386756/effects-of-a-physical-activity-program-on-cardiorespiratory-fitness-and-pulmonary-function-in-obese-women-after-bariatric-surgery-a-pilot-study
#19
Tatiana Onofre, Renata Carlos, Nicole Oliver, Amanda Felismino, Davi Fialho, Renata Corte, Eliane Pereira da Silva, Eudes Godoy, Selma Bruno
BACKGROUND: In severely obese individuals, reducing body weight induced by bariatric surgery is able to promote a reduction in comorbidities and improve respiratory symptoms. However, cardiorespiratory fitness (CRF) reflected by peak oxygen uptake (VO2peak) may not improve in individuals who remain sedentary post-surgery. The objective of this study was to evaluate the effects of a physical training program on CRF and pulmonary function in obese women after bariatric surgery, and to compare them to a control group...
April 7, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28384908/cardiac-effect-of-interstitial-lung-disease-correlated-with-spirometry-and-six-minute-walk-test
#20
Mitali Bharat Agrawal, Nilkanth Tukaram Awad
INTRODUCTION: The cardiac effect of different pulmonary functions, six minute walk distance, arterial blood gases and saturation in Interstitial Lung Disease (ILD) is not much known. So this study, a tertiary care hospital experience that entails to know the various factors in Pulmonary Hypertension (PH) mentioned above causing PH and their correlation with PH. AIM: To study the correlation of PH in patients with ILD with spirometry and six minute walk test (6MWT)...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
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