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Spirometry and lung function

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https://www.readbyqxmd.com/read/28930491/fetal-and-infant-growth-patterns-and-risk-of-lower-lung-function-and-asthma-the-generation-r-study
#1
Herman T den Dekker, Vincent W V Jaddoe, Irwin K Reiss, Johan C de Jongste, Liesbeth Duijts
BACKGROUND: Children with lower birth weight are at increased risk of asthma symptoms. We examined associations of fetal and infant growth with childhood lung function and asthma. METHODS: This study was embedded in a population-based prospective cohort study among 5,635children. Growth was estimated by repeated ultrasounds in 2nd and 3th trimester, and measured at birth and at 3, 6 and 12 months. At age 10 years, spirometry was performed and asthma was assessed by parental questionnaire...
September 20, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28928190/interdisciplinary-model-of-care-radicals-for-early-detection-and-management-of-chronic-obstructive-pulmonary-disease-copd-in-australian-primary-care-study-protocol-for-a-cluster-randomised-controlled-trial
#2
Jenifer Liang, Michael J Abramson, Nicholas Zwar, Grant Russell, Anne E Holland, Billie Bonevski, Ajay Mahal, Benjamin van Hecke, Kirsten Phillips, Paula Eustace, Eldho Paul, Kate Petrie, Sally Wilson, Johnson George
INTRODUCTION: Up to half of all smokers develop clinically significant chronic obstructive pulmonary disease (COPD). Gaps exist in the implementation and uptake of evidence-based guidelines for managing COPD in primary care. We describe the methodology of a cluster randomised controlled trial (cRCT) evaluating the efficacy and cost-effectiveness of an interdisciplinary model of care aimed at reducing the burden of smoking and COPD in Australian primary care settings. METHODS AND ANALYSIS: A cRCT is being undertaken to evaluate an interdisciplinary model of care (RADICALS - Review of Airway Dysfunction and Interdisciplinary Community-based care of Adult Long-term Smokers)...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28913990/association-between-sensitization-to-mold-and-impaired-pulmonary-function-in-children-with-asthma
#3
Jung Hye Byeon, Soohyun Ri, Oyuntulga Amarsaikhan, Eunji Kim, So Hyun Ahn, Ic Sun Choi, Hyung Jin Kim, SungChul Seo, Wonsuck Yoon, Young Yoo
PURPOSE: Recent data indicate that sensitization to mold contributes to the severity and persistence of asthma. In this study, we investigated the relationships between sensitization to mold and lung function parameters in children with asthma. METHODS: We retrospectively reviewed clinical data from 551 asthmatic subjects. We selected subjects who met clinical diagnostic criteria of asthma. Their spirometry, methacholine challenge tests, and measurements of blood eosinophils, serum IgE, eosinophil cationic protein (ECP) and fractional exhaled nitric oxide (FeNO) results were included...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28906034/small-airway-disease-a-different-phenotype-of-early-stage-copd-associated-with-biomass-smoke-exposure
#4
Dongxing Zhao, Yumin Zhou, Changbin Jiang, Zhuxiang Zhao, Fang He, Pixin Ran
BACKGROUND AND OBJECTIVE: Chronic exposure to biomass smoke (BS) can significantly compromise pulmonary function and lead to chronic obstructive pulmonary disease (COPD). To determine whether BS exposure induces a unique phenotype of COPD from an early stage, with different physiopathological features compared with COPD associated with smoking (cigarette-smoke (CS) COPD), we assessed the physiopathology of early COPD associated with BS exposure (BS COPD) by incorporating spirometry, high-resolution computed tomography (HRCT) imaging, bronchoscopy and pathological examinations...
September 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28902960/the-prognostic-significance-of-lung-function-in-stable-heart-failure-outpatients
#5
Louis Lind Plesner, Morten Dalsgaard, Morten Schou, Lars Køber, Jørgen Vestbo, Erik Kjøller, Kasper Iversen
BACKGROUND: This study investigated the impact on all-cause mortality of airflow limitation indicative of chronic obstructive pulmonary disease or restrictive spirometry pattern (RSP) in a stable systolic heart failure population. HYPOTHESIS: Decreased lung function indicates poor survival in heart failure. METHODS: Inclusion criteria: NYHA class II-IV and left ventricular ejection fraction (LVEF) < 45%. Prognosis was assessed with multivariate Cox proportional hazards models...
September 13, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28902919/factors-associated-with-pulmonary-impairment-in-hiv-infected-south-african-adults
#6
Akshay N Gupte, Michelle L Wong, Reginah Msandiwa, Grace L Barnes, Jonathan Golub, Richard E Chaisson, Christopher J Hoffmann, Neil A Martinson
BACKGROUND: HIV-infected individuals have increased risk of developing obstructive lung disease (OLD). Studies from developed countries report high viral load, low CD4 counts, and anti-retroviral therapy (ART) to be associated with OLD; but these findings may not be generalizable to populations in resource-limited settings. METHODS: We conducted a prospective cohort study of lung function in 730 HIV-infected black South African adults. Pre-bronchodilator spirometry was performed at enrollment and repeated annually for three years...
2017: PloS One
https://www.readbyqxmd.com/read/28893868/official-ers-technical-standards-global-lung-function-initiative-reference-values-for-the-carbon-monoxide-transfer-factor-for-caucasians
#7
Sanja Stanojevic, Brian L Graham, Brendan G Cooper, Bruce R Thompson, Kim W Carter, Richard W Francis, Graham L Hall
There are numerous reference equations available for the single-breath transfer factor of the lung for carbon monoxide (T LCO); however, it is not always clear which reference set should be used in clinical practice. The aim of the study was to develop the Global Lung Function Initiative (GLI) all-age reference values for T LCOData from 19 centres in 14 countries were collected to define T LCO reference values. Similar to the GLI spirometry project, reference values were derived using the LMS (lambda, mu, sigma) method and the GAMLSS (generalised additive models for location, scale and shape) programme in R...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28886594/elemental-sulfur-use-and-associations-with-pediatric-lung-function-and-respiratory-symptoms-in-an-agricultural-community-california-usa
#8
Rachel Raanan, Robert B Gunier, John R Balmes, Alyssa J Beltran, Kim G Harley, Asa Bradman, Brenda Eskenazi
BACKGROUND: Elemental sulfur, "the oldest of all pesticides," is the most heavily used agricultural pesticide in California and Europe. Sulfur is considered relatively safe and is used in both conventional and organic farming systems. Adverse respiratory effects have been reported in applicators and animals, but the effect on residential populations, and especially on children living in proximity to fields treated with elemental sulfur, is not known. OBJECTIVES: We evaluated associations between residential proximity to elemental sulfur applications and respiratory symptoms and spirometry of children living in an agricultural community...
August 10, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28886252/total-airway-count-on-computed-tomography-and-the-risk-of-copd-progression-findings-from-a-population-based-study
#9
Miranda Kirby, Naoya Tanabe, Wan C Tan, Guohai Zhou, Ma'en Obeidat, Cameron J Hague, Jonathon Leipsic, Jean Bourbeau, Don D Sin, James C Hogg, Harvey O Coxson
RATIONALE: Studies of excised lungs show that significant airway attrition in the 'quiet' zone occurs early in chronic obstructive pulmonary disease (COPD). OBJECTIVES: To determine if the total number of airways quantified in vivo using computed tomography (CT) reflects early airway-related disease changes and is associated with lung-function decline independent of emphysema in COPD. METHODS: Participants in the multi-centre, population-based, longitudinal CanCOLD study underwent inspiratory/expiratory CT at visit-1; spirometry was performed at four visits over 6-years...
September 8, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28878482/effects-of-high-intensity-aerobic-exercise-on-treadmill-on-maximum-expiratory-lung-capacity-of-elderly-women
#10
Joonsung Park, Dongwook Han
[Purpose] The aim of this study was to examine whether a systematic high intensity aerobic exercise on treadmill was effective in improving pulmonary function. [Subjects and Methods] The subjects of this study were 22 healthy elderly women over 65 years of age who were attending the Senior Welfare Center and Social Welfare Center programs in B city. For the pulmonary function test, a spirometry (Pony FX, COSMED Inc., Italy) was used. The item for measurement of pulmonary function in elderly women was maximum-effort expiratory spirogram (MES)...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28877261/myelodysplastic-syndrome-patients-present-more-severe-respiratory-muscle-impairment-and-reduced-forced-vital-capacity-is-disordered-inflammatory-signaling-the-culprit
#11
Bruno Memória Okubo, Anacélia Gomes de Matos, Howard Lopes Ribeiro Junior, Daniela de Paula Borges, Roberta Taiane Germano de Oliveira, Marilena Facundo de Castro, Manoel Ricardo Alves Martins, Romélia Pinheiro Gonçalves, Pedro Felipe Carvalhedo Bruin, Ronald Feitosa Pinheiro, Silvia Maria Meira Magalhães
BACKGROUND/OBJECTIVES: The ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated with adverse outcomes. Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies with increasing incidence with age and characterized by anemia and other cytopenias. The main objectives of this study were to evaluate respiratory muscle strength and lung function in elderly patients with anemia, compare data between myelodysplastic syndromes and non-clonal anemias and evaluate the influence of serum IL-8 level and NF-kB activity on deteriorate pulmonary function in this specific population...
2017: PloS One
https://www.readbyqxmd.com/read/28874609/modified-medical-research-council-dyspnea-scale-in-gold-classification-better-reflects-physical-activities-of-daily-living
#12
Anelise B Munari, Aline A Gulart, Karoliny Dos Santos, Raysa S Venâncio, Manuela Karloh, Anamaria F Mayer
BACKGROUND: In multidimensional Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification, the choice of the symptom assessment instrument (modified Medical Research Council dyspnea scale [mMRC] or COPD assessment test [CAT]) can lead to a different distribution of patients in each quadrant. Considering that physical activities of daily living (PADL) is an important functional outcome in COPD, the objective of this study was to determine which symptom assessment instrument is more strongly associated with and differentiates better the PADL of patients with COPD...
September 5, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28872938/laps-or-lengths-the-effects-of-different-exercise-programmes-on-asthma-control-in-children
#13
C Carew, Dw Cox
INTRODUCTION: Exercise training has been shown in numerous studies to improve lung function and asthma control in children with asthma. Swimming has been shown to be of benefit in children with asthma, but which form of exercise is better for asthmatics has not been determined to date. The aim of this study was to examine if swimming improved lung function and asthma symptoms in asthmatic children when compared with different forms of exercise and a control group. METHODS: Subjects with asthma were randomly assigned to either one of three different exercise training groups (swimming, football and basketball) or a control group...
September 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28871617/what-is-expected-in-lung-function-after-lung-transplantation-due-to-end-stage-pulmonary-silicosis
#14
Luzielio Alves Sidney, Guilherme Watte, Pedro Augusto Reck Dos Santos, Sadi Marcelo Schio, Spencer Marcelo Camargo, Fabíola Adélia Perin, Bruno Hochhegger, Jose Carlos Felicetti, Jose de Jesus Peixoto Camargo, Jose da Silva Moreira
In the present study, we aimed to determine the impact of lung transplantation (LTx) on pulmonary function tests (PFTs) and survival among patients with end-stage silicosis. We included patients with end-stange silicosis on the wait list for LTx, between January 1989 and July 2015 (N=26). Sixteen of these patients received LTx; 10 were eligible, but did not undergo LTx (non-LTx) during the study period. Retrospective information on PFTs (spirometry [volumes and flows], 6-minute walking test [6MWT], and DLCO) was retrieved from patients' medical charts, including baseline information for all patients, and follow-up information for the LTx...
September 4, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28871575/inert-gas-washout-background-and-application-in-various-lung-diseases
#15
Jakob Usemann, Sophie Yammine, Florian Singer, Philipp Latzin
Multiple breath inert gas washout (MBW) is a lung function technique to measure ventilation inhomogeneity. The technique was developed more than 60 years ago, but not much used for many decades. Technical improvements, easy protocols and higher sensitivity compared with standard lung function tests in some disease groups have led to a recent renaissance of MBW. The lung clearance index (LCI) is a common measure derived from MBW tests, and offers information on lung pathology complementary to that from conventional lung function tests such as spirometry...
September 5, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28871078/impact-of-forced-expiratory-volume-in-1-second-fev1-and-6-minute-walking-distance-at-3-6-and-12-months-and-annually-on-survival-and-occurrence-of-bronchiolitis-obliterans-syndrome-bos-after-lung-transplantation
#16
Mohammed Fakhro, Richard Ingemansson, Lars Algotsson, Sandra Lindstedt
BACKGROUND Development of bronchiolitis obliterans syndrome (BOS) is a great limitation for patient survival in lung transplantation (LTx). A curative treatment for BOS is still missing, and in terminal stages re-transplantation (Re-LTx) is the only salvation. It is possible to slow the progress of BOS if it is detected at an early stage. This might be possible by assessing pulmonary function pattern. MATERIAL AND METHODS Between 1990 and 2014, 278 patients underwent LTx at Skåne University Hospital, Sweden...
September 5, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28862922/adherence-to-dietary-approaches-to-stop-hypertension-dash-dietary-pattern-in-relation-to-chronic-obstructive-pulmonary-disease-copd-a-case-control-study
#17
Mohammad Emami Ardestani, Shokouh Onvani, Ahmad Esmailzadeh, Awat Feizi, Leila Azadbakht
OBJECTIVE: This case-control study was designed to investigate the association between adherences to the Dietary Approaches to Stop Hypertension (DASH) diet in patients with chronic obstructive pulmonary disease (COPD) in comparison to subjects without COPD. DESIGN: This is a case-control study. Usual dietary intake was assessed using a validated food frequency questionnaire. Lung function was evaluated with spirometry testing, and one of the researchers inquired about other respiratory symptoms, including chronic cough, sputum, and breathlessness...
September 1, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28862879/chronic-obstructive-pulmonary-disease-in-hispanics-a-9-year-update
#18
Alejandro Díaz, Bartolomé Celli, Juan C Celedón
Hispanics are the largest minority in the U.S., now encompassing 56.6 million people. A Hispanic or Latino is an individual whose ancestry can be traced to Spain or territories previously under Spanish control. The Hispanic population in the U.S. and Latin America is very diverse for country of origin, nativity, and racial ancestry. Over the last nine years, our knowledge of COPD in Hispanics has improved, due to a better understanding of differences in COPD burden and risk factors across Hispanic subgroups, development of subgroup-specific spirometry reference equations, genetic studies, and better knowledge of barriers and needs in the diagnosis and management of COPD in the Hispanic population...
September 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28862396/association-between-lung-function-physical-activity-level-and-postural-evaluation-variables-in-adult-patients-with-cystic-fibrosis
#19
Inaê Angélica Cherobin, Paulo de Tarso Roth Dalcin, Bruna Ziegler
INTRODUCTION: With the evolution of the cystic fibrosis (CF) disease, the decline of lung function associated with metabolic disorders and malnutrition, causes alterations in respiratory mechanics, musculoskeletal disorders and thoracic deformities, bringing injury to the individual's quality of life. OBJECTIVE: To verify the association between lung function, physical activity level and postural evaluation variables in adults with CF. METHODS: All patients underwent clinical evaluation and spirometry...
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28860744/ischemic-ecg-abnormalities-are-associated-with-an-increased-risk-for-death-among-subjects-with-copd-also-among-those-without-known-heart-disease
#20
Ulf Nilsson, Anders Blomberg, Bengt Johansson, Helena Backman, Berne Eriksson, Anne Lindberg
ABSTRACT PRESENTATION: An abstract, including parts of the results, has been presented at an oral session at the European Respiratory Society International Conference, London, UK, September 2016. BACKGROUND: Cardiovascular comorbidity contributes to increased mortality among subjects with COPD. However, the prognostic value of ECG abnormalities in COPD has rarely been studied in population-based surveys. AIM: To assess the impact of ischemic ECG abnormalities (I-ECG) on mortality among individuals with COPD, compared to subjects with normal lung function (NLF), in a population-based study...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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